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Research Article

Unlocking the Secrets Behind Secondary Metabolism: A Review of Aspergillus flavus from Pathogenicity to Functional Genomics

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Pages 423-459 | Published online: 08 Nov 2003

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Rania Jebali, Samir Abbès, Jalila Ben Salah-Abbès, Ridha Ben Younes, Zohra Haous & Ridha Oueslati. (2015) Ability of Lactobacillus plantarum MON03 to mitigate aflatoxins (B1 and M1) immunotoxicities in mice. Journal of Immunotoxicology 12:3, pages 290-299.
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Shaikhul Islam, Abdul Mannan Akanda, Farjana Sultana & Md. Motaher Hossain. (2014) Chilli rhizosphere fungus Aspergillus spp. PPA1 promotes vegetative growth of cucumber (Cucumis sativus) plants upon root colonisation. Archives of Phytopathology and Plant Protection 47:10, pages 1231-1238.
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Samir Abbès, Jalila Ben Salah-Abbès, Yousra Bouraoui, Sarra Oueslati & Ridha Oueslati. (2012) Natural occurrence of aflatoxins (B1 and M1) in feed, plasma and raw milk of lactating dairy cows in Beja, Tunisia, using ELISA. Food Additives & Contaminants: Part B 5:1, pages 11-15.
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KRN Reddy, B Salleh, B Saad, HK Abbas, CA Abel & WT Shier. (2010) An overview of mycotoxin contamination in foods and its implications for human health. Toxin Reviews 29:1, pages 3-26.
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Antonio Gallo & Francesco Masoero. (2010) In vitro models to evaluate the capacity of different sequestering agents to adsorb aflatoxins. Italian Journal of Animal Science 9:1.
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Antonio Gallo & Francesco Masoero. (2010) In vitro models to evaluate the capacity of different sequestering agents to adsorb aflatoxins. Italian Journal of Animal Science 9:1.
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A. Gallo, F. Masoero, T. Bertuzzi, G. Piva & A. Pietri. (2010) Effect of the inclusion of adsorbents on aflatoxin B1 quantification in animal feedstuffs. Food Additives & Contaminants: Part A 27:1, pages 54-63.
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Hassan Korbekandi, Siavash Iravani & Sajjad Abbasi. (2009) Production of nanoparticles using organisms. Critical Reviews in Biotechnology 29:4, pages 279-306.
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Meng Luo, Robert L. Brown, Zhi-Yuan Chen & Thomas E. Cleveland. (2009) Host genes involved in the interaction between Aspergillus flavus and maize. Toxin Reviews 28:2-3, pages 118-128.
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HK Abbas, JR Wilkinson, RM Zablotowicz, C Accinelli, CA Abel, HA Bruns & MA Weaver. (2009) Ecology of Aspergillus flavus, regulation of aflatoxin production, and management strategies to reduce aflatoxin contamination of corn. Toxin Reviews 28:2-3, pages 142-153.
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Articles from other publishers (36)

Geromy G. Moore, Subbaiah Chalivendra, Brian M. Mack, Matthew K. Gilbert, Jeffrey W. Cary & Kanniah Rajasekaran. (2023) Microbiota of maize kernels as influenced by Aspergillus flavus infection in susceptible and resistant inbreds. Frontiers in Microbiology 14.
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Lina Castano-Duque, Edwin Winzeler, Joshua M. Blackstock, Cheng Liu, Noemi Vergopolan, Marlous Focker, Kristin Barnett, Phillip Ray Owens, H. J. van der Fels-Klerx, Martha M. Vaughan & Kanniah Rajasekaran. (2023) Dynamic geospatial modeling of mycotoxin contamination of corn in Illinois: unveiling critical factors and predictive insights with machine learning. Frontiers in Microbiology 14.
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Khaoula Boudjaber, Yamina Ben Miri, Amina Benabdallah, Nada Bennia, Chaima Hamadi, Boudjema Soumati, Djamel Djenane & Jesus Simal-Gandara. (2023) Evaluation of Antifungal and anti-aflatoxin B1 efficacy of some crude extracts of Chamaerops humilis L. against Aspergillus flavus isolated from peanuts (Arachis hypogea L.). Food Control 152, pages 109858.
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Muwen He, Yao Jin, Mingming Liu, Guanrong Yang, Rongqing Zhou, Jinsong Zhao & Chongde Wu. (2023) Metaproteomic investigation of enzyme profile in daqu used for the production of Nongxiangxing baijiu. International Journal of Food Microbiology 400, pages 110250.
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Cesar A. Arreguin-Perez, Estefan Miranda-Miranda, Jorge Luis Folch-Mallol & Raquel Cossío-Bayúgar. (2023) Identification of Virulence Factors in Entomopathogenic Aspergillus flavus Isolated from Naturally Infected Rhipicephalus microplus. Microorganisms 11:8, pages 2107.
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Cameron K. Tebbi. (2023) Mycoviruses in Fungi: Carcinogenesis of Fungal Agents May Not Always Be Mycotoxin Related. Journal of Fungi 9:3, pages 368.
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Marilyn L. Warburton, Dan Jeffers, Jessie Spencer Smith, Carlos Scapim, Renan Uhdre, Adam Thrash & William Paul Williams. (2022) Comparative Analysis of Multiple GWAS Results Identifies Metabolic Pathways Associated with Resistance to A. flavus Infection and Aflatoxin Accumulation in Maize. Toxins 14:11, pages 738.
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Jane Marian Luis, Ignazio Carbone, Brian M. Mack, Matthew D. Lebar, Jeffrey W. Cary, Matthew K. Gilbert, Deepak Bhatnagar, Carol-Carter Wientjes, Gary A. Payne, Geromy G. Moore, Yaken Obaydeh Ameen & Peter S. Ojiambo. (2022) Development of sexual structures influences metabolomic and transcriptomic profiles in Aspergillus flavus. Fungal Biology 126:3, pages 187-200.
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S. K. Bera, Kirti Rani, J. H. Kamdar, M. K. Pandey, H. Desmae, C. C. Holbrook, M. D. Burow, N. Manivannan, R. S. Bhat, Mital D. Jasani, Satarupa S. Bera, Anand M. Badigannavar, G. Sunkad, Graeme C. Wright, P. Janila & R. K. Varshney. 2022. Genomic Designing for Biotic Stress Resistant Oilseed Crops. Genomic Designing for Biotic Stress Resistant Oilseed Crops 137 214 .
Connel Ching'anda, Joseph Atehnkeng, Ranajit Bandyopadhyay, Kenneth A. Callicott, Marc J. Orbach, Hillary L. Mehl & Peter J. Cotty. (2021) Temperature Influences on Interactions Among Aflatoxigenic Species of Aspergillus Section Flavi During Maize Colonization. Frontiers in Fungal Biology 2.
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Thibault Nordey, Simon Boniface Boni, Mawufe Komi Agbodzavu, Robert Mwashimaha, Nickson Mlowe, Srinivasan Ramasamy & Emilie Deletre. (2021) Comparison of biological methods to control Aphis fabae Scopoli (Hemiptera: Aphididae) on kalanchoe crops in East Africa. Crop Protection 142, pages 105520.
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Ran Xu, Niel A. Karrow, Umesh K. Shandilya, Lv-hui Sun & Haruki Kitazawa. (2020) In-Vitro Cell Culture for Efficient Assessment of Mycotoxin Exposure, Toxicity and Risk Mitigation. Toxins 12:3, pages 146.
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Roua Rejeb, Gunther Antonissen, Marthe De Boevre, Christ’l Detavernier, Mario Van de Velde, Sarah De Saeger, Richard Ducatelle, Madiha Hadj Ayed & Achraf Ghorbal. (2019) Calcination Enhances the Aflatoxin and Zearalenone Binding Efficiency of a Tunisian Clay. Toxins 11:10, pages 602.
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Kayla K. Pennerman, Guohua Yin, Joan W. Bennett & Sui-Sheng T. Hua. (2019) Aspergillus flavus NRRL 35739, a Poor Biocontrol Agent, May Have Increased Relative Expression of Stress Response Genes. Journal of Fungi 5:2, pages 53.
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Xiaomei Shu, David P. LivingstonIIIIII, Charles P. Woloshuk & Gary A. Payne. (2017) Comparative Histological and Transcriptional Analysis of Maize Kernels Infected with Aspergillus flavus and Fusarium verticillioides. Frontiers in Plant Science 8.
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Walid Korani, Ye Chu, Corley Holbrook, Josh Clevenger & Peggy Ozias-Akins. (2017) Genotypic Regulation of Aflatoxin Accumulation but Not Aspergillus Fungal Growth upon Post-Harvest Infection of Peanut (Arachis hypogaea L.) Seeds. Toxins 9:7, pages 218.
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Gary A. Payne. 2016. Peanuts. Peanuts 347 361 .
Max Schubert, Marcel Houdelet, Karl-Heinz Kogel, Rainer Fischer, Stefan Schillberg & Greta Nölke. (2015) Thanatin confers partial resistance against aflatoxigenic fungi in maize (Zea mays). Transgenic Research 24:5, pages 885-895.
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Cesare Accinelli, Hamed K. Abbas, Alberto Vicari & W. Thomas Shier. (2014) Aflatoxin contamination of corn under different agro-environmental conditions and biocontrol applications. Crop Protection 63, pages 9-14.
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Andrea L. Dolezal, Xiaomei Shu, Gregory R. OBrian, Dahlia M. Nielsen, Charles P. Woloshuk, Rebecca S. Boston & Gary A. Payne. (2014) Aspergillus flavus infection induces transcriptional and physical changes in developing maize kernels. Frontiers in Microbiology 5.
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Geromy G. Moore, Jacalyn L. Elliott, Rakhi Singh, Bruce W. Horn, Joe W. Dorner, Eric A. Stone, Sofia N. Chulze, German G. Barros, Manjunath K. Naik, Graeme C. Wright, Kerstin Hell & Ignazio Carbone. (2013) Sexuality Generates Diversity in the Aflatoxin Gene Cluster: Evidence on a Global Scale. PLoS Pathogens 9:8, pages e1003574.
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Cesare Accinelli, Mariangela Mencarelli, M. Ludovica Saccà, Alberto Vicari & Hamed K. Abbas. (2012) Managing and monitoring of Aspergillus flavus in corn using bioplastic-based formulations. Crop Protection 32, pages 30-35.
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Yen-Ting Chen, Mei-Ju Lin, Ching-Hui Yang & Wen-Hsiung Ko. (2011) Characterization of a fungistatic substance produced by Aspergillus flavus isolated from soil and its significance in nature. New Biotechnology 28:6, pages 679-683.
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A. McDaniel, W.E. Holmes, K.L. Armbrust, D.L. Sparks & A. E. Brown. (2011) Effect of Matrix Clean-Up for Aflatoxin Analysis in Corn and Dried Distillers Grains. Natural Resources 02:04, pages 250-257.
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F. Wu, D. Bhatnagar, T. Bui-Klimke, I. Carbone, R. Hellmich, G. Munkvold, P. Paul, G. Payne & E. Takle. (2011) Climate change impacts on mycotoxin risks in US maize. World Mycotoxin Journal 4:1, pages 79-93.
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Gary A. Payne, D. Ryan Georgianna, Jiujiang Yu, Ken Ehrlich, Greg Obrian & Deepak Bhatnagar. 2010. Genomes of Foodborne and Waterborne Pathogens. Genomes of Foodborne and Waterborne Pathogens 259 270 .
Sigal Horowitz Brown, James B. Scott, Jeyanthi Bhaheetharan, William C. Sharpee, Lane Milde, Richard A. Wilson & Nancy P. Keller. (2009) Oxygenase Coordination Is Required for Morphological Transition and the Host–Fungus Interaction of Aspergillus flavus . Molecular Plant-Microbe Interactions® 22:7, pages 882-894.
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F. Masoero, A. Gallo, D. Diaz, G. Piva & M. Moschini. (2009) Effects of the procedure of inclusion of a sequestering agent in the total mixed ration on proportional aflatoxin M1 excretion into milk of lactating dairy cows. Animal Feed Science and Technology 150:1-2, pages 34-45.
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M. Weaver, R. Hoagland, C. Boyette & R. Zablotowicz. (2009) Macrocyclic trichothecene production and sporulation by a biological control strain of Myrothecium verrucaria is regulated by cultural conditions . World Mycotoxin Journal 2:1, pages 35-43.
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M. Moschini, A. Gallo, G. Piva & F. Masoero. (2008) The effects of rumen fluid on the in vitro aflatoxin binding capacity of different sequestering agents and in vivo release of the sequestered toxin. Animal Feed Science and Technology 147:4, pages 292-309.
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Nevcihan Gursoy, Bulent Sarac, Nedim Durmus, Ahmet Parlak, Sahin Yildirim, Tijen Kaya & Ihsan Bagcivan. (2008) Changes in spontaneous contractions of rat ileum by aflatoxin in vitro. Food and Chemical Toxicology 46:6, pages 2124-2127.
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MAREN A. KLICH. (2007) Aspergillus flavus: the major producer of aflatoxin. Molecular Plant Pathology 8:6, pages 713-722.
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Maren A. Klich. (2007) Environmental and developmental factors influencing aflatoxin production by Aspergillus flavus and Aspergillus parasiticus. Mycoscience 48:2, pages 71-80.
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W. Thomas Shier, Yanbin Lao, Terry W.J. Steele & Hamed K. Abbas. (2005) Yellow pigments used in rapid identification of aflatoxin-producing Aspergillus strains are anthraquinones associated with the aflatoxin biosynthetic pathway. Bioorganic Chemistry 33:6, pages 426-438.
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