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Molecular and Cellular Biology Volume 28, 2008 - Issue 19
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Article

Pax5 and Linker Histone H1 Coordinate DNA Methylation and Histone Modifications in the 3′ Regulatory Region of the Immunoglobulin Heavy Chain Locus

Vincenzo Giambra1 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York10461
,
Sabrina Volpi1 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York10461
,
Alexander V. Emelyanov1 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York10461
,
David Pflugh2 Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut06520
,
Alfred L. M. Bothwell2 Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut06520
,
Paolo Norio1 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York10461
,
Yuhong Fan1 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York10461
,
Zhongliang Ju1 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York10461
,
Arthur I. Skoultchi1 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York10461
,
Richard R. Hardy3 Division of Basic Science, Fox Chase Cancer Center, 333 Cottman Ave., Philadelphia, Pennsylvania19111
,
Domenico Frezza4 Department of Biology Enrico Calef, University of Tor Vergata, Rome, Italy
&
Barbara K. Birshtein1 Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York10461Correspondence[email protected]
 show all
Pages 6123-6133 | Received 12 Feb 2008, Accepted 10 Jul 2008, Published online: 27 Mar 2023

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Yoichi Yamada & Sho Sasaki. (2020) A method for identifying allele-specific hydroxymethylation. Epigenetics 15:3, pages 231-250.
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Fatima-Zohra Braikia, Caroline Conte, Mohamed Moutahir, Yves Denizot, Michel Cogné & Ahmed Amine Khamlichi. (2015) Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element. Molecular and Cellular Biology 35:19, pages 3370-3380.
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Weiguo Han, Miao Shi & Simon D Spivack. (2013) Site-specific methylated reporter constructs for functional analysis of DNA methylation. Epigenetics 8:11, pages 1176-1187.
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Mark N. Cruickshank, Paul Besant & Daniela Ulgiati. (2010) The impact of histone post-translational modifications on developmental gene regulation. Amino Acids 39:5, pages 1087-1105.
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Christelle Vincent-Fabert, Véronique Truffinet, Remi Fiancette, Nadine Cogné, Michel Cogné & Yves Denizot. (2009) Ig Synthesis and Class Switching Do Not Require the Presence of the hs4 Enhancer in the 3′ IgH Regulatory Region. The Journal of Immunology 182:11, pages 6926-6932.
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