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Article

The RNA Binding Protein hnRNP Q Modulates the Utilization of Exon 7 in the Survival Motor Neuron 2 (SMN2) Gene

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Pages 6929-6938 | Received 20 Aug 2008, Accepted 03 Sep 2008, Published online: 27 Mar 2023

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Ravindra N. Singh, Joonbae Seo & Natalia N. Singh. (2020) RNA in spinal muscular atrophy: therapeutic implications of targeting. Expert Opinion on Therapeutic Targets 24:8, pages 731-743.
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Přemysl Souček, Kamila Réblová, Michal Kramárek, Lenka Radová, Tereza Grymová, Pavla Hujová, Tatiana Kováčová, Matej Lexa, Lucie Grodecká & Tomáš Freiberger. (2019) High-throughput analysis revealed mutations’ diverging effects on SMN1 exon 7 splicing. RNA Biology 16:10, pages 1364-1376.
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Hung-Hsi Chen, Hsin-I Yu, Wen-Cheng Chiang, Yu-De Lin, Ben-Chang Shia & Woan-Yuh Tarn. (2012) hnRNP Q Regulates Cdc42-Mediated Neuronal Morphogenesis. Molecular and Cellular Biology 32:12, pages 2224-2238.
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Natalia N. Singh & Ravindra N. Singh. (2011) Alternative splicing in spinal muscular atrophy underscores the role of an intron definition model. RNA Biology 8:4, pages 600-606.
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Natalia N. Singh, Joonbae Seo, Eric W. Ottesen, Maria Shishimorova, Dhruva Bhattacharya & Ravindra N. Singh. (2011) TIA1 Prevents Skipping of a Critical Exon Associated with Spinal Muscular Atrophy. Molecular and Cellular Biology 31:5, pages 935-954.
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Natalia N. Singh, Shaine Hoffman, Prabhakara P. Reddi & Ravindra N. Singh. (2021) Spinal muscular atrophy: Broad disease spectrum and sex-specific phenotypes. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867:4, pages 166063.
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Fabrizio Fabbiano, Jessica Corsi, Elena Gurrieri, Caterina Trevisan, Michela Notarangelo & Vito G. D'Agostino. (2020) RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?. Journal of Extracellular Vesicles 10:2.
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Ying Chen, Jingru Chan, Wei Chen, Jianwei Li, Meng Sun, Gayathiri Sathyamoorthy Kannan, Yu-Keung Mok, Yuren Adam Yuan & Chacko Jobichen. (2020) SYNCRIP, a new player in pri-let-7a processing. RNA 26:3, pages 290-305.
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Tae‐Jun Kim, Jae Hun Sung, Jae‐Cheon Shin & Do‐Yeon Kim. (2019) CRISPR/Cas‐mediated Fubp1 silencing disrupts circadian oscillation of Per1 protein via downregulating Syncrip expression. Cell Biology International 44:2, pages 424-432.
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Lauren M. Gittings, Sandrine C. Foti, Bridget C. Benson, Priya Gami-Patel, Adrian M. Isaacs & Tammaryn Lashley. (2019) Heterogeneous nuclear ribonucleoproteins R and Q accumulate in pathological inclusions in FTLD-FUS. Acta Neuropathologica Communications 7:1.
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Hui-Wen Chung, Ju-Chen Weng, Chih-En King, Chih-Fan Chuang, Wei-Yuan Chow & Yen-Chung Chang. (2019) BDNF elevates the axonal levels of hnRNPs Q and R in cultured rat cortical neurons. Molecular and Cellular Neuroscience 98, pages 97-108.
Crossref
Federica Rizzo, Monica Nizzardo, Shikha Vashisht, Erika Molteni, Valentina Melzi, Michela Taiana, Sabrina Salani, Pamela Santonicola, Elia Di Schiavi, Monica Bucchia, Andreina Bordoni, Irene Faravelli, Nereo Bresolin, Giacomo Pietro Comi, Uberto Pozzoli & Stefania Corti. (2019) Key role of SMN/SYNCRIP and RNA-Motif 7 in spinal muscular atrophy: RNA-Seq and motif analysis of human motor neurons. Brain 142:2, pages 276-294.
Crossref
Yaoyao Zou, Siqi Xu, Youjun Xiao, Qian Qiu, Maohua Shi, Jingnan Wang, Liuqin Liang, Zhongping Zhan, Xiuyan Yang, Nancy Olsen, Song Guo Zheng & Hanshi Xu. (2018) Long noncoding RNA LERFS negatively regulates rheumatoid synovial aggression and proliferation. Journal of Clinical Investigation 128:10, pages 4510-4524.
Crossref
Sara Cappelli, Maurizio Romano & Emanuele Buratti. (2018) Systematic Analysis of Gene Expression Profiles Controlled by hnRNP Q and hnRNP R, Two Closely Related Human RNA Binding Proteins Implicated in mRNA Processing Mechanisms. Frontiers in Molecular Biosciences 5.
Crossref
Yu-Chu Wang, Kung-Chao Chang, Bo-Wen Lin, Jenq-Chang Lee, Chien-Hsien Lai, Li-Jyuan Lin, Yun Yen, Chang-Shen Lin, Shiang-Jie Yang, Peng-Chan Lin, Chung-Ta Lee & Liang-Yi Hung. (2018) The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes. Experimental & Molecular Medicine 50:6, pages 1-14.
Crossref
Fruzsina Hobor, Andre Dallmann, Neil J. Ball, Carla Cicchini, Cecilia Battistelli, Roksana W. Ogrodowicz, Evangelos Christodoulou, Stephen R. Martin, Alfredo Castello, Marco Tripodi, Ian A. Taylor & Andres Ramos. (2018) A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets. Nature Communications 9:1.
Crossref
Ravindra N. Singh & Natalia N. Singh. 2018. RNA Metabolism in Neurodegenerative Diseases. RNA Metabolism in Neurodegenerative Diseases 31 61 .
Smita Kulkarni, Veron Ramsuran, Marijana Rucevic, Sukhvinder Singh, Alexandra Lied, Viraj Kulkarni, Colm O’hUigin, Sylvie Le Gall & Mary Carrington. (2017) Posttranscriptional Regulation of HLA-A Protein Expression by Alternative Polyadenylation Signals Involving the RNA-Binding Protein Syncrip. The Journal of Immunology 199:11, pages 3892-3899.
Crossref
Leslie C. Sutherland, Philippe Thibault, Mathieu Durand, Elvy Lapointe, Jose M. Knee, Ariane Beauvais, Irina Kalatskaya, Sarah C. Hunt, Julie J. Loiselle, Justin G. Roy, Sarah J. Tessier, Gustavo Ybazeta, Lincoln Stein, Rashmi Kothary, Roscoe Klinck & Benoit Chabot. (2017) Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA. BMC Molecular Biology 18:1.
Crossref
Ayan Banerjee, Katherine E. Vest, Grace K. Pavlath & Anita H. Corbett. (2017) Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing. Nucleic Acids Research 45:18, pages 10706-10725.
Crossref
Catherine E. Dominguez, David Cunningham & Dawn S. Chandler. (2017) SMN regulation in SMA and in response to stress: new paradigms and therapeutic possibilities. Human Genetics 136:9, pages 1173-1191.
Crossref
Wen-Yo Tu, Julie E. Simpson, J. Robin Highley & Paul R. Heath. (2017) Spinal muscular atrophy: Factors that modulate motor neurone vulnerability. Neurobiology of Disease 102, pages 11-20.
Crossref
Yu-Chia Chen, Jan-Gowth Chang, Ting-Yuan Liu, Yuh-Jyh Jong, Wei-Lin Cheng & Chung-Yee Yuo. (2017) Securinine enhances SMN2 exon 7 inclusion in spinal muscular atrophy cells. Biomedicine & Pharmacotherapy 88, pages 708-714.
Crossref
Ravindra N. Singh, Matthew D. Howell, Eric W. Ottesen & Natalia N. Singh. (2017) Diverse role of survival motor neuron protein. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860:3, pages 299-315.
Crossref
Chien-Hsien Lai, Yu-Chuan Huang, Jenq-Chang Lee, Joseph Ta-Chien Tseng, Kung-Chao Chang, Yen-Ju Chen, Nai-Jhu Ding, Pao-Hsuan Huang, Wen-Chang Chang, Bo-Wen Lin, Ruo-Yu Chen, Yu-Chu Wang, Yi-Chien Lai & Liang-Yi Hung. (2017) Translational upregulation of Aurora-A by hnRNP Q1 contributes to cell proliferation and tumorigenesis in colorectal cancer. Cell Death & Disease 8:1, pages e2555-e2555.
Crossref
Larisa Tratnjek, Marko Živin & Gordana Glavan. (2017) Synaptotagmin 7 and SYNCRIP proteins are ubiquitously expressed in the rat brain and co-localize in Purkinje neurons. Journal of Chemical Neuroanatomy 79, pages 12-21.
Crossref
N.N. Singh, M.D. Howell & R.N. Singh. 2017. Spinal Muscular Atrophy. Spinal Muscular Atrophy 75 97 .
Laura Santangelo, Giorgio Giurato, Carla Cicchini, Claudia Montaldo, Carmine Mancone, Roberta Tarallo, Cecilia Battistelli, Tonino Alonzi, Alessandro Weisz & Marco Tripodi. (2016) The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting. Cell Reports 17:3, pages 799-808.
Crossref
Erkan Y Osman, Charles W WashingtonIIIIII, Kevin A Kaifer, Chiara Mazzasette, Teresa N Patitucci, Kyra M Florea, Madeline E Simon, Chien-Ping Ko, Allison D Ebert & Christian L Lorson. (2016) Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy. Molecular Therapy 24:9, pages 1592-1601.
Crossref
Thomas Geuens, Delphine Bouhy & Vincent Timmerman. (2016) The hnRNP family: insights into their role in health and disease. Human Genetics 135:8, pages 851-867.
Crossref
Joonbae Seo, Natalia N. Singh, Eric W. Ottesen, Senthilkumar Sivanesan, Maria Shishimorova & Ravindra N. Singh. (2016) Oxidative Stress Triggers Body-Wide Skipping of Multiple Exons of the Spinal Muscular Atrophy Gene. PLOS ONE 11:4, pages e0154390.
Crossref
Eric W. Ottesen, Matthew D. Howell, Natalia N. Singh, Joonbae Seo, Elizabeth M. Whitley & Ravindra N. Singh. (2016) Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy. Scientific Reports 6:1.
Crossref
Dairong Feng, Yi Cheng, Yan Meng, Liping Zou, Shangzhi Huang & Jiuyong Xie. (2015) Multiple effects of curcumin on promoting expression of the exon 7-containing SMN2 transcript. Genes & Nutrition 10:6.
Crossref
Vittoria Pagliarini, Laura Pelosi, Maria Blaire Bustamante, Annalisa Nobili, Maria Grazia Berardinelli, Marcello D’Amelio, Antonio Musarò & Claudio Sette. (2015) SAM68 is a physiological regulator of SMN2 splicing in spinal muscular atrophy . Journal of Cell Biology 211:1, pages 77-90.
Crossref
Wei Shen, Rong Yin, Cheng Wang, Meng Zhu, Wen Zhou, Na Qin, Jie Sun, Jia Liu, Jing Dong, Guangfu Jin, Hongxia Ma, Zhibin Hu, Hongbing Shen, Lin Xu & Juncheng Dai. (2015) Polymorphisms in alternative splicing associated genes are associated with lung cancer risk in a Chinese population. Lung Cancer 89:3, pages 238-242.
Crossref
Selena M. Sagan, Jasmin Chahal & Peter Sarnow. (2015) cis-Acting RNA elements in the hepatitis C virus RNA genome. Virus Research 206, pages 90-98.
Crossref
Natalia N. Singh, Brian M. Lee & Ravindra N. Singh. (2015) Splicing regulation in spinal muscular atrophy by an RNA structure formed by long-distance interactions. Annals of the New York Academy of Sciences 1341:1, pages 176-187.
Crossref
Yu-Chia Chen, Jan-Gowth Chang, Yuh-Jyh Jong, Ting-Yuan Liu & Chung-Yee Yuo. (2015) High Expression Level of Tra2-β1 Is Responsible for Increased SMN2 Exon 7 Inclusion in the Testis of SMA Mice. PLOS ONE 10:3, pages e0120721.
Crossref
Matthew J. Walsh, Johnathan Cooper-Knock, Jennifer E. Dodd, Matthew J. Stopford, Simeon R. Mihaylov, Janine Kirby, Pamela J. Shaw & Guillaume M. Hautbergue. (2015) Invited Review: Decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art. Neuropathology and Applied Neurobiology 41:2, pages 109-134.
Crossref
Claribel D. Wee, Mallory A. Havens, Francine M. Jodelka & Michelle L. Hastings. (2014) Targeting SR Proteins Improves SMN Expression in Spinal Muscular Atrophy Cells. PLoS ONE 9:12, pages e115205.
Crossref
Benjamin Dombert, Rajeeve Sivadasan, Christian M. Simon, Sibylle Jablonka & Michael Sendtner. (2014) Presynaptic Localization of Smn and hnRNP R in Axon Terminals of Embryonic and Postnatal Mouse Motoneurons. PLoS ONE 9:10, pages e110846.
Crossref
Suzanne M. McDermott, Lu Yang, James M. Halstead, Russell S. Hamilton, Carine Meignin & Ilan Davis. (2014) Drosophila Syncrip modulates the expression of mRNAs encoding key synaptic proteins required for morphology at the neuromuscular junction . RNA 20:10, pages 1593-1606.
Crossref
Erkan Y. Osman, Madeline R. Miller, Kate L. Robbins, Abby M. Lombardi, Arleigh K. Atkinson, Amanda J. Brehm & Christian L. Lorson. (2014) Morpholino antisense oligonucleotides targeting intronic repressor Element1 improve phenotype in SMA mouse models. Human Molecular Genetics 23:18, pages 4832-4845.
Crossref
Callie P. Wigington, Kathryn R. Williams, Michael P. Meers, Gary J. Bassell & Anita H. Corbett. (2014) Poly(A) RNA ‐binding proteins and polyadenosine RNA : new members and novel functions . WIREs RNA 5:5, pages 601-622.
Crossref
Pádraig J. MulcahyKayleigh IremongerEvangelia KarykaSaúl Herranz-MartínKa-To ShumJanice Kal Van TamMimoun Azzouz. (2014) Gene Therapy: A Promising Approach to Treating Spinal Muscular Atrophy. Human Gene Therapy 25:7, pages 575-586.
Crossref
Sakari Vanharanta, Christina B Marney, Weiping Shu, Manuel Valiente, Yilong Zou, Aldo Mele, Robert B Darnell & Joan Massagué. (2014) Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer. eLife 3.
Crossref
Sunghee Cho, Heegyum Moon, Tiing Jen Loh, Hyun Kyung Oh, Darren Reese Williams, D. Joshua Liao, Jianhua Zhou, Michael R. Green, Xuexiu Zheng & Haihong Shen. (2014) PSF contacts exon 7 of SMN2 pre-mRNA to promote exon 7 inclusion. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1839:6, pages 517-525.
Crossref
Sunghee Cho, Heegyum Moon, Tiing Jen Loh, Huyn Kyung Oh, Sungchan Cho, Hyon E. Choy, Woo Keun Song, Jang-Soo Chun, Xuexiu Zheng & Haihong Shen. (2014) hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1839:4, pages 306-315.
Crossref
Sunghee Cho, Heegyum Moon, Tiing Jen Loh, Hyun Kyung Oh, Hey-Ran Kim, Myung-Geun Shin, D. Joshua Liao, Jianhua Zhou, Xuexiu Zheng & Haihong Shen. (2014) 3′ Splice Site Sequences of Spinal Muscular Atrophy Related SMN2 Pre-mRNA Include Enhancers for Nearby Exons. The Scientific World Journal 2014, pages 1-9.
Crossref
Francesco Danilo Tiziano, Judith Melki & Louise R. Simard. (2013) Solving the puzzle of spinal muscular atrophy: What are the missing pieces?. American Journal of Medical Genetics Part A 161:11, pages 2836-2845.
Crossref
Andrew G.L. Douglas & Matthew J.A. Wood. (2013) Splicing therapy for neuromuscular disease. Molecular and Cellular Neuroscience 56, pages 169-185.
Crossref
Alexandre Chaumet, Sandrine Castella, Laïla Gasmi, Aurélie Fradin, Gilles Clodic, Gérard Bolbach, Robert Poulhe, Philippe Denoulet & Jean-Christophe Larcher. (2013) Proteomic analysis of interleukin enhancer binding factor 3 (Ilf3) and nuclear factor 90 (NF90) interactome. Biochimie 95:6, pages 1146-1157.
Crossref
Yuri V. Svitkin, Akiko Yanagiya, Alexey E. Karetnikov, Tommy Alain, Marc R. Fabian, Arkady Khoutorsky, Sandra Perreault, Ivan Topisirovic & Nahum Sonenberg. (2013) Control of Translation and miRNA-Dependent Repression by a Novel Poly(A) Binding Protein, hnRNP-Q. PLoS Biology 11:5, pages e1001564.
Crossref
Shreeram C. NallarDhananjaya V. Kalvakolanu. (2013) Regulation of snoRNAs in Cancer: Close Encounters with Interferon. Journal of Interferon & Cytokine Research 33:4, pages 189-198.
Crossref
Michael Niepmann. 2013. Hepatitis C Virus: From Molecular Virology to Antiviral Therapy. Hepatitis C Virus: From Molecular Virology to Antiviral Therapy 143 166 .
Monique A Lorson & Christian L Lorson. (2012) SMN-inducing compounds for the treatment of spinal muscular atrophy. Future Medicinal Chemistry 4:16, pages 2067-2084.
Crossref
Thomas O. Crawford, Sergey V. Paushkin, Dione T. Kobayashi, Suzanne J. Forrest, Cynthia L. Joyce, Richard S. Finkel, Petra Kaufmann, Kathryn J. Swoboda, Danilo Tiziano, Rosa Lomastro, Rebecca H. Li, Felicia L. Trachtenberg, Thomas Plasterer & Karen S. Chen. (2012) Evaluation of SMN Protein, Transcript, and Copy Number in the Biomarkers for Spinal Muscular Atrophy (BforSMA) Clinical Study. PLoS ONE 7:4, pages e33572.
Crossref
Lei Xing, Xiaodi Yao, Kathryn R. Williams & Gary J. Bassell. (2012) Negative regulation of RhoA translation and signaling by hnRNP-Q1 affects cellular morphogenesis. Molecular Biology of the Cell 23:8, pages 1500-1509.
Crossref
Do-Yeon Kim, Eunyee Kwak, Sung-Hoon Kim, Kyung-Ha Lee, Kyung-Chul Woo & Kyong-Tai Kim. (2011) hnRNP Q mediates a phase-dependent translation-coupled mRNA decay of mouse Period3. Nucleic Acids Research 39:20, pages 8901-8914.
Crossref
N. Owen, H. Zhou, A. A. Malygin, J. Sangha, L. D. Smith, F. Muntoni & I. C. Eperon. (2011) Design principles for bifunctional targeted oligonucleotide enhancers of splicing. Nucleic Acids Research 39:16, pages 7194-7208.
Crossref
Wen Xie & Robert B. Denman. (2011) Protein Methylation and Stress Granules: Posttranslational Remodeler or Innocent Bystander?. Molecular Biology International 2011, pages 1-14.
Crossref
Francine M. Jodelka, Allison D. Ebert, Dominik M. Duelli & Michelle L. Hastings. (2010) A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Human Molecular Genetics 19:24, pages 4906-4917.
Crossref
Jordan T. Gladman, Thomas W. Bebee, Chris Edwards, Xueyong Wang, Zarife Sahenk, Mark M. Rich & Dawn S. Chandler. (2010) A humanized Smn gene containing the SMN2 nucleotide alteration in exon 7 mimics SMN2 splicing and the SMA disease phenotype. Human Molecular Genetics 19:21, pages 4239-4252.
Crossref
Xiang-Yu Long, Ji-Rui Wang, Thérèse Ouellet, Hélène Rocheleau, Yu-Ming Wei, Zhi-En Pu, Qian-Tao Jiang, Xiu-Jing Lan & You-Liang Zheng. (2010) Genome-wide identification and evaluation of novel internal control genes for Q-PCR based transcript normalization in wheat. Plant Molecular Biology 74:3, pages 307-311.
Crossref
Siew Ping Han, Yue Hang Tang & Ross Smith. (2010) Functional diversity of the hnRNPs: past, present and perspectives. Biochemical Journal 430:3, pages 379-392.
Crossref
Marka van Blitterswijk & John E. Landers. (2010) RNA processing pathways in amyotrophic lateral sclerosis. neurogenetics 11:3, pages 275-290.
Crossref
C. L. Lorson, H. Rindt & M. Shababi. (2010) Spinal muscular atrophy: mechanisms and therapeutic strategies. Human Molecular Genetics 19:R1, pages R111-R118.
Crossref
Simona Pedrotti, Pamela Bielli, Maria Paola Paronetto, Fabiola Ciccosanti, Gian Maria Fimia, Stefan Stamm, James L Manley & Claudio Sette. (2010) The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. The EMBO Journal 29:7, pages 1235-1247.
Crossref
Jordan T. Gladman & Dawn S. Chandler. (2009) Intron 7 conserved sequence elements regulate the splicing of the SMN genes. Human Genetics 126:6, pages 833-841.
Crossref
Michelle L. HastingsJoel BerniacYing Hsiu LiuPaul AbatoFrancine M. JodelkaLea BarthelSujatha KumarCaroline DudleyMark NelsonKelley LarsonJason EdmondsTodd BowserMichael DraperPaul HigginsAdrian R. Krainer. (2009) Tetracyclines That Promote SMN2 Exon 7 Splicing as Therapeutics for Spinal Muscular Atrophy . Science Translational Medicine 1:5.
Crossref
Jennifer L. Kabat, Sergio Barberan-Soler & Alan M. Zahler. (2009) HRP-2, the Caenorhabditis elegans Homolog of Mammalian Heterogeneous Nuclear Ribonucleoproteins Q and R, Is an Alternative Splicing Factor That Binds to UCUAUC Splicing Regulatory Elements. Journal of Biological Chemistry 284:42, pages 28490-28497.
Crossref

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