229
Views
109
CrossRef citations to date
0
Altmetric
Minireview

The Capable ABL: What Is Its Biological Function?

Pages 1188-1197 | Published online: 20 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Adnan Erol. (2022) Genotoxicity-Stimulated and CYLD-Driven Malignant Transformation. Cancer Management and Research 14, pages 2339-2356.
Read now
Neel H. Shah, Jeanine F. Amacher, Laura M. Nocka & John Kuriyan. (2018) The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases. Critical Reviews in Biochemistry and Molecular Biology 53:5, pages 535-563.
Read now
Chi-Chiang Tu & Jean Y. J. Wang. (2016) EnABLing microprocessor for apoptosis . Molecular & Cellular Oncology 3:2.
Read now

Articles from other publishers (105)

Zhenzhou Huang & Yanjie Tan. (2023) The Potential of Cylindromatosis (CYLD) as a Therapeutic Target in Oxidative Stress-Associated Pathologies: A Comprehensive Evaluation. International Journal of Molecular Sciences 24:9, pages 8368.
Crossref
Pallab Dutta & Neelanjana Sengupta. (2022) Efficient Interrogation of the Kinetic Barriers Demarcating Catalytic States of a Tyrosine Kinase with Optimal Physical Descriptors and Mixture Models. ChemPhysChem 24:6.
Crossref
Louise Thines, Zhigang Li & David B. Sacks. (2023) IQGAP1 Is a Phosphotyrosine-Regulated Scaffold for SH2-Containing Proteins. Cells 12:3, pages 483.
Crossref
América Chandía-Cristi, Nicolás Stuardo, Cristian Trejos, Nancy Leal, Daniela Urrutia, Francisca C. Bronfman & Alejandra Álvarez Rojas. (2023) c-Abl Tyrosine Kinase Is Required for BDNF-Induced Dendritic Branching and Growth. International Journal of Molecular Sciences 24:3, pages 1944.
Crossref
Rabiatul Basria S. M. N. Mydin, Alam Mahboob, Srimala Sreekantan, Khairul Arifah Saharudin, Ekhlas Qaid Qazem, Roshasnorlyza Hazan & Mustafa Fadzil Farid Wajidi. (2023) Mechano‐cytoskeleton remodeling mechanism and molecular docking studies on nanosurface technology: Titania nanotube arrays. Biotechnology and Applied Biochemistry.
Crossref
Yildiz Koca, Linh T. Vuong, Jaskirat Singh, Edward Giniger & Marek Mlodzik. (2022) Notch-dependent Abl signaling regulates cell motility during ommatidial rotation in Drosophila. Cell Reports 41:10, pages 111788.
Crossref
Zichao Yang, Yangcheng Ai, Shanhe Wan, Zilong Yang, Honghao Li, Zhonghuang Li, Chunhui Huang, Lishun Zhang, Mingxia Li, Jiajie Zhang & Tingting Zhang. (2022) Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect. Bioorganic & Medicinal Chemistry 74, pages 117069.
Crossref
Alexander Rudich, Ramiro Garzon & Adrienne Dorrance. (2022) Non-Coding RNAs Are Implicit in Chronic Myeloid Leukemia Therapy Resistance. International Journal of Molecular Sciences 23:20, pages 12271.
Crossref
Li Luo, Panpan Jiang, Qianglin Chen, Jiang Chang, Yukai Jing, Xi Luo, Heng Gu, Yanmei Huang, Ran Chen, Ju Liu, Danqing Kang, Qi Liu, Yi Wang, Guofeng Fang, Yingzi Zhu, Fei Guan, Jiahui Lei, Lu Yang, Chaohong Liu & Xin Dai. (2022) Abelson tyrosine kinase controls BCR signalling and B‐cell differentiation by promoting B‐cell metabolism . Immunology 167:2, pages 181-196.
Crossref
Peixin Jiang, Suni Tang, Hogan Hudgins, Tate Smalligan, Xue Zhou, Anuja Kamat, Janaki Dharmarpandi, Tarek Naguib, Xinli Liu & Zonghan Dai. (2022) The Abl/Abi signaling links WAVE regulatory complex to Cbl E3 ubiquitin ligase and is essential for breast cancer cell metastasis. Neoplasia 32, pages 100819.
Crossref
Allison B. Coffin, Emily Dale, Emilee Doppenberg, Forrest Fearington, Tamasen Hayward, Jordan Hill & Olivia Molano. (2022) Putative COVID-19 therapies imatinib, lopinavir, ritonavir, and ivermectin cause hair cell damage: A targeted screen in the zebrafish lateral line. Frontiers in Cellular Neuroscience 16.
Crossref
Sitong Sun, Manshu Wang, Yu Yuan, Shuo Wang, Haoran Ding, Chenrui Liang, Xiaomeng Li, Simiao Fan & Yubo Li. (2022) A new strategy for the rapid identification and validation of direct toxicity targets of psoralen-induced hepatotoxicity. Toxicology Letters 363, pages 11-26.
Crossref
William Bachman, Rupalatha Maddala, Ayon Chakraborty, Camelia Eldawy, Nikolai P. Skiba & Ponugoti V. Rao. (2022) Glucocorticoids Preferentially Influence Expression of Nucleoskeletal Actin Network and Cell Adhesive Proteins in Human Trabecular Meshwork Cells. Frontiers in Cell and Developmental Biology 10.
Crossref
Daisuke Miyamoto, Kenji Takeuchi, Kazuyasu Chihara, Shigeharu Fujieda & Kiyonao Sada. (2022) Protein tyrosine kinase Abl promotes hepatitis C virus particle assembly via interaction with viral substrate activator NS5A. Journal of Biological Chemistry 298:4, pages 101804.
Crossref
Guang-Fei Wang, Qincai Dong, Yu Bai, Jing Gu, Qingping Tao, Junjie Yue, Rui Zhou, Xiayang Niu, Lin Zhu, Caiwei Song, Tong Zheng, Di Wang, Yanwen Jin, Hainan Liu, Cheng Cao & Xuan Liu. (2022) c-Abl kinase-mediated phosphorylation of γ-tubulin promotes γ-tubulin ring complexes assembly and microtubule nucleation. Journal of Biological Chemistry 298:4, pages 101778.
Crossref
Tamara Marín, Andrés E. Dulcey, Fabián Campos, Catalina de la Fuente, Mariana Acuña, Juan Castro, Claudio Pinto, María José Yañez, Cristian Cortez, David W. McGrath, Pablo J. Sáez, Kirill Gorshkov, Wei Zheng, Noel Southall, Maria Carmo-Fonseca, Juan Marugán, Alejandra R. Alvarez & Silvana Zanlungo. (2022) c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease. Frontiers in Cell and Developmental Biology 10.
Crossref
Vidhi Malik, Navaneethan Radhakrishnan, Sunil C. Kaul, Renu Wadhwa & Durai Sundar. (2022) Computational Identification of BCR-ABL Oncogenic Signaling as a Candidate Target of Withaferin A and Withanone. Biomolecules 12:2, pages 212.
Crossref
Bryan K. Chan, Eileen Seward, Michael Lainchbury, Thomas F. Brewer, Le An, Toby Blench, Matthew W. Cartwright, Grace Ka Yan Chan, Edna F. Choo, Jason Drummond, Richard L. Elliott, Emanuela Gancia, Lewis Gazzard, Baihua Hu, Graham E. Jones, Xifeng Luo, Andrew Madin, Sushant Malhotra, John G. Moffat, Jodie Pang, Laurent Salphati, Christopher J. Sneeringer, Craig E. Stivala, Binqing Wei, Weiru Wang, Ping Wu & Timothy P. Heffron. (2021) Discovery of Spiro-azaindoline Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1). ACS Medicinal Chemistry Letters 13:1, pages 84-91.
Crossref
Milton H. Werner & C. Warren Olanow. (2021) Parkinson's Disease Modification Through Abl Kinase Inhibition: An Opportunity. Movement Disorders 37:1, pages 6-15.
Crossref
Hyojung Kim, Jeong-Yong Shin, Areum Jo, Ji Hun Kim, Sangwook Park, Jeong-Yun Choi, Ho Chul Kang, Valina L Dawson, Ted M Dawson, Joo-Ho Shin & Yunjong Lee. (2021) Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegeneration. Brain 144:12, pages 3674-3691.
Crossref
Naofumi Mukaida, Yamato Tanabe & Tomohisa Baba. (2021) Cancer non-stem cells as a potent regulator of tumor microenvironment: a lesson from chronic myeloid leukemia. Molecular Biomedicine 2:1.
Crossref
Hanieh Mojtahedi, Niloufar Yazdanpanah & Nima Rezaei. (2021) Chronic myeloid leukemia stem cells: targeting therapeutic implications. Stem Cell Research & Therapy 12:1.
Crossref
Jillian Hattaway Luttman, Ashley Colemon, Benjamin Mayro & Ann Marie Pendergast. (2021) Role of the ABL tyrosine kinases in the epithelial–mesenchymal transition and the metastatic cascade. Cell Communication and Signaling 19:1.
Crossref
Fiona C. Rodrigues, Gangadhar Hari, K. S. R. Pai, Akhil Suresh, Usha Y. Nayak, N. V. Anilkumar & Goutam Thakur. (2021) Molecular modeling piloted analysis for semicarbazone derivative of curcumin as a potent Abl-kinase inhibitor targeting colon cancer. 3 Biotech 11:12.
Crossref
Qi Bian, Joshua C. Anderson, Xian Wen Zhang, Zhi Qiang Huang, Kerstin Ebefors, Jenny Nyström, Stacy Hall, Lea Novak, Bruce A. Julian, Christopher D. Willey & Jan Novak. (2021) Mesangioproliferative Kidney Diseases and Platelet-Derived Growth Factor–Mediated AXL Phosphorylation. Kidney Medicine 3:6, pages 1003-1013.e1.
Crossref
Adrián González-Martín, Tomás Moyano, Daniela A. Gutiérrez, Franciso J. Carvajal, Waldo Cerpa, Jonathan G. Hanley, Rodrigo A. Gutiérrez & Alejandra R. Álvarez. (2021) c-Abl regulates a synaptic plasticity-related transcriptional program involved in memory and learning. Progress in Neurobiology 205, pages 102122.
Crossref
Philipe Oliveira Fernandes, Diego Magno Martins, Aline de Souza Bozzi, João Paulo A. Martins, Adolfo Henrique de Moraes & Vinícius Gonçalves Maltarollo. (2021) Molecular insights on ABL kinase activation using tree-based machine learning models and molecular docking. Molecular Diversity 25:3, pages 1301-1314.
Crossref
Min-Hye Kim, Gi-Eun Yang, Mi-So Jeong, Jeong-Yeon Mun, Sang-Yeop Lee, Jong-Kil Nam, Yung Hyun Choi, Tae Nam Kim & Sun-Hee Leem. (2021) VNTR polymorphism in the breakpoint region of ABL1 and susceptibility to bladder cancer. BMC Medical Genomics 14:1.
Crossref
Albina Ibrayeva, Maxwell Bay, Elbert Pu, David J. Jörg, Lei Peng, Heechul Jun, Naibo Zhang, Daniel Aaron, Congrui Lin, Galen Resler, Axel Hidalgo, Mi-Hyeon Jang, Benjamin D. Simons & Michael A. Bonaguidi. (2021) Early stem cell aging in the mature brain. Cell Stem Cell 28:5, pages 955-966.e7.
Crossref
M.J. Yañez, F. Campos, T. Marín, A.D. Klein, A.H. Futerman, A.R. Alvarez & S. Zanlungo. (2021) c-Abl activates RIPK3 signaling in Gaucher disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1867:5, pages 166089.
Crossref
Hyewon Lee, Igor Novitzky Basso & Dennis Dong Hwan Kim. (2021) Target spectrum of the BCR-ABL tyrosine kinase inhibitors in chronic myeloid leukemia. International Journal of Hematology 113:5, pages 632-641.
Crossref
Claudio Cerchione, Franco Locatelli & Giovanni Martinelli. (2021) Dasatinib in the Management of Pediatric Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia. Frontiers in Oncology 11.
Crossref
Fabián Montecino, Natalia González, Natasha Blanco, Manuel J. Ramírez, Adrián González-Martín, Alejandra R. Alvarez & Hugo Olguín. (2021) c-Abl Kinase Is Required for Satellite Cell Function Through Pax7 Regulation. Frontiers in Cell and Developmental Biology 9.
Crossref
Miguel Mendivil-Perez, Carlos Velez-Pardo, Gloria E. David-Yepes, Javier E. Fox & Marlene Jimenez-Del-Rio. (2020) TPEN exerts selective anti-leukemic efficacy in ex vivo drug-resistant childhood acute leukemia. BioMetals 34:1, pages 49-66.
Crossref
Meghan C. Gage & Thimmasettappa Thippeswamy. (2021) Inhibitors of Src Family Kinases, Inducible Nitric Oxide Synthase, and NADPH Oxidase as Potential CNS Drug Targets for Neurological Diseases. CNS Drugs 35:1, pages 1-20.
Crossref
Masilamani Elizabeth Sobhia, G. Siva Kumar, Antara Mallick, Harmanpreet Singh, Kranthi Kumar, Meenakshi Chaurasiya, Monica Singh, Narendra Gera, Sindhuja Deverakonda & Vinay Baghel. (2020) Computational and Biological Investigations on Abl1 Tyrosine Kinase: A Review. Current Drug Targets 22:1, pages 38-51.
Crossref
Han Sian Joshua Cheong, Mark Nona, Samantha Barbara Guerra & Mark Francis VanBerkum. (2020) The first quarter of the C-terminal domain of Abelson regulates the WAVE regulatory complex and Enabled in axon guidance. Neural Development 15:1.
Crossref
Casey A. Pollard, Michael P. Morran & Andrea L. Nestor-Kalinoski. (2020) The COVID-19 pandemic: a global health crisis. Physiological Genomics 52:11, pages 549-557.
Crossref
Pablo S. Contreras, Pablo J. Tapia, Lila González-Hódar, Ivana Peluso, Chiara Soldati, Gennaro Napolitano, Maria Matarese, Macarena Las Heras, Cristian Valls, Alexis Martinez, Elisa Balboa, Juan Castro, Nancy Leal, Frances M. Platt, Andrzej Sobota, Dominic Winter, Andrés D. Klein, Diego L. Medina, Andrea Ballabio, Alejandra R. Alvarez & Silvana Zanlungo. (2020) c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder. iScience 23:11, pages 101691.
Crossref
Peng Zeng & Alvin Schmaier. (2020) Ponatinib and other CML Tyrosine Kinase Inhibitors in Thrombosis. International Journal of Molecular Sciences 21:18, pages 6556.
Crossref
Guo Yu, Jie Fu, Ana Romo, Baojie Li & Huijuan Liu. (2020) Abl1 deletion in gut stem cells suppresses p53 induction and promotes colitis-associated tumor formation . Journal of Molecular Cell Biology 12:9, pages 738-740.
Crossref
Tina R. Lewis, Jesse Smith, Kallie Griffin, Stephanie Aguiar, Kristen F. Rueb, Natalie Holmberg-Douglas, Ellen M. Sampson, Skylar Tomasetti, Sofia Rodriguez, David L. Stachura & Carolynn C. Arpin. (2020) NHD2-15, a novel antagonist of Growth Factor Receptor-Bound Protein-2 (GRB2), inhibits leukemic proliferation. PLOS ONE 15:8, pages e0236839.
Crossref
Wei Wang, Mingqi Li, Suriyan Ponnusamy, Yayun Chi, Jingyan Xue, Beshoy Fahmy, Meiyun Fan, Gustavo A. Miranda-Carboni, Ramesh Narayanan, Jiong Wu & Zhao-Hui Wu. (2020) ABL1-dependent OTULIN phosphorylation promotes genotoxic Wnt/β-catenin activation to enhance drug resistance in breast cancers. Nature Communications 11:1.
Crossref
Zhengwei Yan, Karthigayan Shanmugasundaram, Dongwen Ma, Jiayu Luo, Shiwen Luo & Hai Rao. (2020) The N-terminal domain of the non-receptor tyrosine kinase ABL confers protein instability and suppresses tumorigenesis. Journal of Biological Chemistry 295:27, pages 9069-9075.
Crossref
Ran Friedman & Sinisa Bjelic. (2020) Simulations Studies of Protein Kinases that are Molecular Targets in Cancer. Israel Journal of Chemistry 60:7, pages 667-680.
Crossref
Abdulaziz B. Hamid & Ruben C. Petreaca. (2020) Secondary Resistant Mutations to Small Molecule Inhibitors in Cancer Cells. Cancers 12:4, pages 927.
Crossref
Hélène Losson, Michael Schnekenburger, Mario Dicato & Marc Diederich. (2020) HDAC6—An Emerging Target Against Chronic Myeloid Leukemia?. Cancers 12:2, pages 318.
Crossref
Sun H. Park & Yusuke Shiozawa. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 273 280 .
Halil I. Ciftci, Nilüfer Bayrak, Hatice Yıldırım, Mahmut Yıldız, Mohamed O. Radwan, Masami Otsuka, Mikako Fujita & Amaç F. Tuyun. (2019) Discovery and structure–activity relationship of plastoquinone analogs as anticancer agents against chronic myelogenous leukemia cells. Archiv der Pharmazie 352:12, pages 1900170.
Crossref
Daniela A. Gutierrez, Lina M. Vargas, América Chandia-Cristi, Catalina de la Fuente, Nancy Leal & Alejandra R. Alvarez. (2019) c-Abl Deficiency Provides Synaptic Resiliency Against Aβ-Oligomers. Frontiers in Cellular Neuroscience 13.
Crossref
A. Golonko, H. Lewandowska, R. Świsłocka, U.T. Jasińska, W. Priebe & W. Lewandowski. (2019) Curcumin as tyrosine kinase inhibitor in cancer treatment. European Journal of Medicinal Chemistry 181, pages 111512.
Crossref
Xin Chen, Giuseppe Gumina & Kristopher G. Virga. (2019) Recent Advances in Drug Repurposing for Parkinson’s Disease. Current Medicinal Chemistry 26:28, pages 5340-5362.
Crossref
Yunjie Lu, Fangqiao Lv, Ming Kong, Xuyang Chen, Yunfei Duan, Xuemin Chen, Donglin Sun, Mingming Fang & Yong Xu. (2019) A cAbl-MRTF-A Feedback Loop Contributes to Hepatic Stellate Cell Activation. Frontiers in Cell and Developmental Biology 7.
Crossref
Nikolai Mugue, Nadezhda Terekhanova, Sergey Afanasyev & Aleksei Krasnov. (2019) Transcriptome sequencing of hybrid bester sturgeon: Responses to poly (I:C) in the context of comparative immunogenomics. Fish & Shellfish Immunology 93, pages 888-894.
Crossref
Ameer Ali Bohio, Aman Sattout, Ruoxi Wang, Ke Wang, Rajiv Kumar Sah, Xiaolan Guo, Xianlu Zeng, Yueshuang Ke, Istvan Boldogh & Xueqing Ba. (2019) c-Abl–Mediated Tyrosine Phosphorylation of PARP1 Is Crucial for Expression of Proinflammatory Genes. The Journal of Immunology 203:6, pages 1521-1531.
Crossref
Mrityunjay Sarkar, Aurpan Majumder & Sanjay Dhar Roy. (2019) A Nonlinear Multivariate Approach to Identify Differentially Coexpressed Pathways. A Nonlinear Multivariate Approach to Identify Differentially Coexpressed Pathways.
Masashi Nishikawa, Shun Nakano, Hiromu Nakao, Katsuya Sato, Tsuyoshi Sugiyama, Yukihiro Akao, Hitoshi Nagaoka, Hisashi Yamakawa, Takahiro Nagase & Hiroshi Ueda. (2019) The interaction between PLEKHG2 and ABL1 suppresses cell growth via the NF-κB signaling pathway in HEK293 cells. Cellular Signalling 61, pages 93-107.
Crossref
Groves B. Dixon & Carly D. Kenkel. (2019) Molecular convergence and positive selection associated with the evolution of symbiont transmission mode in stony corals. Proceedings of the Royal Society B: Biological Sciences 286:1901, pages 20190111.
Crossref
Markel Olabarria, Silvia Pasini, Carlo Corona, Pablo Robador, Cheng Song, Hardik Patel & Roger Lefort. (2019) Dysfunction of the ubiquitin ligase E3A Ube3A/E6-AP contributes to synaptic pathology in Alzheimer’s disease. Communications Biology 2:1.
Crossref
Wen-bo Ren, Xiao-jing Xia, Jing Huang, Wen-fei Guo, Yan-yi Che, Ting-hao Huang & Lian-cheng Lei. (2019) Interferon-γ regulates cell malignant growth via the c-Abl/HDAC2 signaling pathway in mammary epithelial cellsγ 干扰素通过c-Abl/HDAC2 信号通路调节乳腺上 皮细胞恶性生长. Journal of Zhejiang University-SCIENCE B 20:1, pages 39-48.
Crossref
Ryuzaburo Yuki, Takashi Tatewaki, Noritaka Yamaguchi, Kazumasa Aoyama, Takuya Honda, Sho Kubota, Mariko Morii, Ichiro Manabe, Takahisa Kuga, Takeshi Tomonaga & Naoto Yamaguchi. (2018) Desuppression of TGF-β signaling via nuclear c-Abl-mediated phosphorylation of TIF1γ/TRIM33 at Tyr-524, -610, and -1048. Oncogene 38:5, pages 637-655.
Crossref
Chunyan He, Rina Plattner, Vivek Rangnekar, Binhua Zhou, Chunming Liu, Rachel L. Stewart, Bin Huang, Chi Wang & Thomas C. Tucker. (2018) Potential protein markers for breast cancer recurrence: a retrospective cohort study. Cancer Causes & Control 30:1, pages 41-51.
Crossref
Qinlian Jiao, Lei Bi, Yidan Ren, Shuliang Song, Qin Wang & Yun-shan Wang. (2018) Advances in studies of tyrosine kinase inhibitors and their acquired resistance. Molecular Cancer 17:1.
Crossref
Wagner Ricardo Montor, Andrei Ronaldo Oliveira Silva Escar Salas & Fabiana Henriques Machado de Melo. (2018) Receptor tyrosine kinases and downstream pathways as druggable targets for cancer treatment: the current arsenal of inhibitors. Molecular Cancer 17:1.
Crossref
Simona Soverini, Manuela Mancini, Luana Bavaro, Michele Cavo & Giovanni Martinelli. (2018) Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy. Molecular Cancer 17:1.
Crossref
Yu Zhou, Yukio Yamamura, Masatoshi Ogawa, Ryosuke Tsuji, Koichiro Tsuchiya, Jiro Kasahara & Satoshi Goto. (2018) c-Abl Inhibition Exerts Symptomatic Antiparkinsonian Effects Through a Striatal Postsynaptic Mechanism. Frontiers in Pharmacology 9.
Crossref
Rakshamani Tripathi, Zulong Liu & Rina Plattner. (2018) Enabling Tumor Growth and Progression: Recent Progress in Unraveling the Functions of ABL Kinases in Solid Tumor Cells. Current Pharmacology Reports 4:5, pages 367-379.
Crossref
Shubhra Rastogi, Amini Hwang, Josolyn Chan & Jean Y. J. Wang. (2018) Extracellular vesicles transfer nuclear Abl-dependent and radiation-induced miR-34c into unirradiated cells to cause bystander effects. Molecular Biology of the Cell 29:18, pages 2228-2242.
Crossref
Susan I. Daraiseh, Ari Kassardjian, Karen E. Alexander, Raed Rizkallah & Myra M. Hurt. (2018) c-Abl phosphorylation of Yin Yang 1's conserved tyrosine 254 in the spacer region modulates its transcriptional activity. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1865:9, pages 1173-1186.
Crossref
Kathryn A. Schiel. (2018) A new etiologic model for Alzheimers Disease. Medical Hypotheses 111, pages 27-35.
Crossref
Jiaoyue Long, Guoning Liao, Yinna Wang & Dale D. Tang. (2018) Specific protein 1, c-Abl, and ERK1/2 form a regulatory loop. Journal of Cell Science.
Crossref
Anna V. Leopold, Konstantin G. Chernov & Vladislav V. Verkhusha. (2018) Optogenetically controlled protein kinases for regulation of cellular signaling. Chemical Society Reviews 47:7, pages 2454-2484.
Crossref
Han S. J. Cheong & Mark F. A. VanBerkum. (2017) Long disordered regions of the C-terminal domain of Abelson tyrosine kinase have specific and additive functions in regulation and axon localization. PLOS ONE 12:12, pages e0189338.
Crossref
Banyuhay P. Serrano, Hannah S. Szydlo, Dominique Alfandari & Jeanne A. Hardy. (2017) Active site–adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9. Journal of Biological Chemistry 292:52, pages 21352-21365.
Crossref
Limin Wang, Dawei Wang, Bowen Xing, Ying-cai Tan, Jianyun Huang, Bingqian Liu, Viktoriya Syrovatkina, Cedric Espenel, Geri Kreitzer, Lin Guo, J. Jillian Zhang & Xin-Yun Huang. (2017) G-Protein Gα13 Functions with Abl Kinase to Regulate Actin Cytoskeletal Reorganization. Journal of Molecular Biology 429:24, pages 3836-3849.
Crossref
Saurav Brahmachari, Senthilkumar S. Karuppagounder, Preston Ge, Saebom Lee, Valina L. Dawson, Ted M. Dawson & Han Seok Ko. (2017) c-Abl and Parkinson’s Disease: Mechanisms and Therapeutic Potential. Journal of Parkinson's Disease 7:4, pages 589-601.
Crossref
Hiroshi Nishi, Kazuhiro Furuhashi, Xavier Cullere, Gurpanna Saggu, Mark J. Miller, Yunfeng Chen, Florencia Rosetti, Samantha L. Hamilton, Lihua Yang, Spencer P. Pittman, Jiexi Liao, Jan M. Herter, Jeffrey C. Berry, Daniel J. DeAngelo, Cheng Zhu, George C. Tsokos & Tanya N. Mayadas. (2017) Neutrophil FcγRIIA promotes IgG-mediated glomerular neutrophil capture via Abl/Src kinases. Journal of Clinical Investigation 127:10, pages 3810-3826.
Crossref
Jimok Yoon, Sang Bum Kim, Giasuddin Ahmed, Jerry W. Shay & Jonathan R. Terman. (2017) Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling. Developmental Cell 42:2, pages 117-129.e8.
Crossref
Chevaun D Morrison, Jenny C Chang, Ruth A Keri & William P Schiemann. (2017) Mutant p53 dictates the oncogenic activity of c-Abl in triple-negative breast cancers. Cell Death & Disease 8:6, pages e2899-e2899.
Crossref
Alessandro Fantin, Anastasia Lampropoulou, Valentina Senatore, James T. Brash, Claudia Prahst, Clemens A. Lange, Sidath E. Liyanage, Claudio Raimondi, James W. Bainbridge, Hellmut G. Augustin & Christiana Ruhrberg. (2017) VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation. Journal of Experimental Medicine 214:4, pages 1049-1064.
Crossref
Shuhei Morita, S. Armando Villalta, Hannah C. Feldman, Ames C. Register, Wendy Rosenthal, Ingeborg T. Hoffmann-Petersen, Morvarid Mehdizadeh, Rajarshi Ghosh, Likun Wang, Kevin Colon-Negron, Rosa Meza-Acevedo, Bradley J. Backes, Dustin J. Maly, Jeffrey A. Bluestone & Feroz R. Papa. (2017) Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes. Cell Metabolism 25:4, pages 883-897.e8.
Crossref
Giuseppe Tridente. 2017. Adverse Events and Oncotargeted Kinase Inhibitors. Adverse Events and Oncotargeted Kinase Inhibitors 695 705 .
Giuseppe Tridente. 2017. Adverse Events and Oncotargeted Kinase Inhibitors. Adverse Events and Oncotargeted Kinase Inhibitors 641 693 .
Christine M. Morris & Suzanne M. Benjes. 2017. Encyclopedia of Cancer. Encyclopedia of Cancer 460 472 .
Gajanan Sathe, Sneha M. Pinto, Nazia Syed, Vishalakshi Nanjappa, Hitendra S. Solanki, Santosh Renuse, Sandip Chavan, Aafaque Ahmad Khan, Arun H. Patil, Raja Sekhar Nirujogi, Bipin Nair, Premendu Prakash Mathur, T. S. Keshava Prasad, Harsha Gowda & Aditi Chatterjee. (2016) Phosphotyrosine profiling of curcumin-induced signaling. Clinical Proteomics 13:1.
Crossref
Fabienne Lamballe, Sara Toscano, Filippo Conti, Maria Arechederra, Nathalie Baeza, Dominique Figarella-Branger, Françoise Helmbacher & Flavio Maina. (2016) Coordination of signalling networks and tumorigenic properties by ABL in glioblastoma cells. Oncotarget 7:46, pages 74747-74767.
Crossref
Tianhe Huang, Fuling Zhou, Feng Wang-Johanning, Kejun Nan & Yongchang Wei. (2016) Depression accelerates the development of gastric cancer through reactive oxygen species-activated ABL1 (Review). Oncology Reports 36:5, pages 2435-2443.
Crossref
Lisbell D. Estrada, David Chamorro, María José Yañez, Marcelo Gonzalez, Nancy Leal, Rommy von Bernhardi, Andrés E. Dulcey, Juan Marugan, Marc Ferrer, Claudio Soto, Silvana Zanlungo, Nibaldo C. Inestrosa & Alejandra R. Alvarez. (2016) Reduction of Blood Amyloid-β Oligomers in Alzheimer’s Disease Transgenic Mice by c-Abl Kinase Inhibition. Journal of Alzheimer's Disease 54:3, pages 1193-1205.
Crossref
Arnau Sebé-Pedrós, Marcia Ivonne Peña, Salvador Capella-Gutiérrez, Meritxell Antó, Toni Gabaldón, Iñaki Ruiz-Trillo & Eduard Sabidó. (2016) High-Throughput Proteomics Reveals the Unicellular Roots of Animal Phosphosignaling and Cell Differentiation. Developmental Cell 39:2, pages 186-197.
Crossref
Fernando Pagan, Michaeline Hebron, Ellen H. Valadez, Yasar Torres-Yaghi, Xu Huang, Reversa R. Mills, Barbara M. Wilmarth, Hellen Howard, Connell Dunn, Alexis Carlson, Abigail Lawler, Sean L. Rogers, Ramsey A. Falconer, Jaeil Ahn, Zhaoxia Li & Charbel Moussa. (2016) Nilotinib Effects in Parkinson’s disease and Dementia with Lewy bodies. Journal of Parkinson's Disease 6:3, pages 503-517.
Crossref
Amy R Dwyer, Kellie A Mouchemore, James H Steer, Andrew J Sunderland, Natalia G Sampaio, Eloise L Greenland, David A Joyce & Fiona J Pixley. (2016) Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration. Journal of Leukocyte Biology 100:1, pages 163-175.
Crossref
Yashodhara DasguptaMateusz KoptyraGrazyna HoserKanchan KantekureDarshan RoyBarbara GornickaMargaret Nieborowska-SkorskaElisabeth Bolton-GillespieSabine Cerny-ReitererMarkus MüschenPeter ValentMariusz A. WasikChristine RichardsonOliver HantschelHeiko van der Kuip, Tomasz Stoklosa & Tomasz Skorski. (2016) Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases. Blood 127:17, pages 2131-2143.
Crossref
Leena Ylösmäki, Riku Fagerlund, Inka Kuisma, Ilkka Julkunen & Kalle Saksela. (2016) Nuclear Translocation of Crk Adaptor Proteins by the Influenza A Virus NS1 Protein. Viruses 8:4, pages 101.
Crossref
Dario Palmieri, Mario Scarpa, Anna Tessari, Rexhep Uka, Foued Amari, Cindy Lee, Timothy Richmond, Claudia Foray, Tyler Sheetz, Ashley Braddom, Christin E. Burd, Jeffrey D. Parvin, Thomas Ludwig, Carlo M. Croce & Vincenzo Coppola. (2016) Ran Binding Protein 9 (RanBP9) is a novel mediator of cellular DNA damage response in lung cancer cells. Oncotarget 7:14, pages 18371-18383.
Crossref
Mohammad B. HossainRehnuma ShifatDavid G. JohnsonMark T. Bedford, Konrad R. GabrusiewiczNahir Cortes-SantiagoXuemei Luo, Zhimin LuRavesanker Ezhilarasan, Erik P. SulmanHong JiangShawn S. C. LiFrederick F. LangJessica TylerMien-Chie HungJuan FueyoCandelaria Gomez-Manzano. (2016) TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1. Science Advances 2:4.
Crossref
Lauren Caldemeyer, Michael Dugan, John Edwards & Luke Akard. (2016) Long-Term Side Effects of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia. Current Hematologic Malignancy Reports 11:2, pages 71-79.
Crossref
Elizabeth M. Selwan, Brendan T. Finicle, Seong M. Kim & Aimee L. Edinger. (2016) Attacking the supply wagons to starve cancer cells to death. FEBS Letters 590:7, pages 885-907.
Crossref
Emmy D. G. Fleuren, Luxi Zhang, Jianmin Wu & Roger J. Daly. (2016) The kinome 'at large' in cancer. Nature Reviews Cancer 16:2, pages 83-98.
Crossref
Adil R. Sarhan, Trushar R. Patel, Alana R. Cowell, Michael G. Tomlinson, Carina Hellberg, John K. Heath, Debbie L. Cunningham & Neil A. Hotchin. (2016) LAR protein tyrosine phosphatase regulates focal adhesions via CDK1. Journal of Cell Science.
Crossref
Aaditya Khatri, Jun Wang & Ann Marie Pendergast. (2016) Multifunctional Abl kinases in health and disease. Journal of Cell Science 129:1, pages 9-16.
Crossref
Lauren E. Tebay, Holly Robertson, Stephen T. Durant, Steven R. Vitale, Trevor M. Penning, Albena T. Dinkova-Kostova & John D. Hayes. (2015) Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease. Free Radical Biology and Medicine 88, pages 108-146.
Crossref
Chi-Chiang TuYan ZhongLouis NguyenAaron TsaiPriya SrideviWoan-Yuh TarnJean Y. J. Wang. (2015) The kinase ABL phosphorylates the microprocessor subunit DGCR8 to stimulate primary microRNA processing in response to DNA damage. Science Signaling 8:383.
Crossref
Byung Hak Ha, Mark Adam Simpson, Anthony J. Koleske & Titus J. Boggon. (2015) Structure of the ABL2/ARG kinase in complex with dasatinib. Acta Crystallographica Section F Structural Biology Communications 71:4, pages 443-448.
Crossref
Christine M. Morris & Suzanne M. Benjes. 2014. Encyclopedia of Cancer. Encyclopedia of Cancer 1 14 .
Stefania Gonfloni. (2014) Defying c-Abl signaling circuits through small allosteric compounds. Frontiers in Genetics 5.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.