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Research Article

Expression and Regulation by Interferon of a Double-Stranded-RNA-Specific Adenosine Deaminase from Human Cells: Evidence for Two Forms of the Deaminase

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Pages 5376-5388 | Received 12 Apr 1995, Accepted 05 Jul 1995, Published online: 30 Mar 2023

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Hanne Poulsen, Jakob Nilsson, Christian K. Damgaard, Jan Egebjerg & Jørgen Kjems. (2001) CRM1 Mediates the Export of ADAR1 through a Nuclear Export Signal within the Z-DNA Binding Domain. Molecular and Cellular Biology 21:22, pages 7862-7871.
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Fang Lai, Chun-Xia Chen, Kenneth C. Carter & Kazuko Nishikura. (1997) Editing of Glutamate Receptor B Subunit Ion Channel RNAs by Four Alternatively Spliced DRADA2 Double-Stranded RNA Adenosine Deaminases. Molecular and Cellular Biology 17:5, pages 2413-2424.
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Sonali Bhakta & Toshifumi Tsukahara. (2020) Artificial RNA Editing with ADAR for Gene Therapy. Current Gene Therapy 20:1, pages 44-54.
Crossref
Isabel C Vallecillo-Viejo, Noa Liscovitch-Brauer, Juan F Diaz Quiroz, Maria F Montiel-Gonzalez, Sonya E Nemes, Kavita J Rangan, Simon R Levinson, Eli Eisenberg & Joshua J C Rosenthal. (2020) Spatially regulated editing of genetic information within a neuron. Nucleic Acids Research 48:8, pages 3999-4012.
Crossref
Xiang Yi Kong, Erik Sebastian Vik, Meh Sameen Nawaz, Natalia Berges, Tuva Børresdatter Dahl, Cathrine Vågbø, Rajikala Suganthan, Filip Segers, Sverre Holm, Ana Quiles-Jiménez, Ida Gregersen, Cathrine Fladeby, Pål Aukrust, Magnar Bjørås, Arne Klungland, Bente Halvorsen & Ingrun Alseth. (2020) Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma. Nucleic Acids Research 48:8, pages 4463-4479.
Crossref
Prajakta Bajad, Florian Ebner, Fabian Amman, Brigitta Szabó, Utkarsh Kapoor, Greeshma Manjali, Alwine Hildebrandt, Michael P Janisiw & Michael F Jantsch. (2020) An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype. Nucleic Acids Research 48:6, pages 3286-3303.
Crossref
Mako Yanai, Shohei Kojima, Madoka Sakai, Ryo Komorizono, Keizo Tomonaga & Akiko Makino. (2020) ADAR2 Is Involved in Self and Nonself Recognition of Borna Disease Virus Genomic RNA in the Nucleus. Journal of Virology 94:6.
Crossref
Zhe Li, Ruofan Qi, Qingde Wang, Hongyu Li, Jijun Hu & Lijun Sun. (2020) Aberrant Overexpression of RNA-Editing Enzyme ADAR1 Promotes the Progression of Endometriosis. Reproductive Sciences 27:2, pages 575-584.
Crossref
Eli Eisenberg. 2020. Evolutionary Biology—A Transdisciplinary Approach. Evolutionary Biology—A Transdisciplinary Approach 79 98 .
Xue Liu, Yu Fu, Jiadong Huang, Meng Wu, Zhenxing Zhang, Rongyao Xu, Ping Zhang, Shouwei Zhao, Laikui Liu & Hongbing Jiang. (2019) ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation. Journal of Experimental & Clinical Cancer Research 38:1.
Crossref
Mamta Jain, Michael F. Jantsch & Konstantin Licht. (2019) The Editor’s I on Disease Development. Trends in Genetics 35:12, pages 903-913.
Crossref
Liat Samuelov & Eli Sprecher. 2019. Harper's Textbook of Pediatric Dermatology. Harper's Textbook of Pediatric Dermatology 1499 1514 .
Natalia Berges, Meh Sameen Nawaz, Tuva Børresdatter Dahl, Lars Hagen, Magnar Bjørås, Jon K. Laerdahl & Ingrun Alseth. (2019) Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform. PLOS ONE 14:11, pages e0225081.
Crossref
Shalom Hillel Roth, Erez Y. Levanon & Eli Eisenberg. (2019) Genome-wide quantification of ADAR adenosine-to-inosine RNA editing activity. Nature Methods 16:11, pages 1131-1138.
Crossref
Ying Li, Matthias Göhl, Ke Ke, Christopher D. Vanderwal & Robert C. Spitale. (2019) Identification of Adenosine-to-Inosine RNA Editing with Acrylonitrile Reagents. Organic Letters 21:19, pages 7948-7951.
Crossref
Peng Wang, Shirong Yu, Jianyong Liu, Dezhi Zhang & Xiaojing Kang. (2019) Seven novel mutations of ADAR in multi‐ethnic pedigrees with dyschromatosis symmetrica hereditaria in China . Molecular Genetics & Genomic Medicine 7:10.
Crossref
Guangyan Liu, Xiancai Ma, Zhe Wang, Kousho Wakae, Yaochang Yuan, Zhangping He, Hironori Yoshiyama, Hisashi Iizasa, Hui Zhang, Mami Matsuda, Ryuichi Sugiyama, Zhiyu Yuan, Masamichi Muramatsu & Linghua Li. (2019) Adenosine deaminase acting on RNA-1 (ADAR1) inhibits hepatitis B virus (HBV) replication by enhancing microRNA-122 processing. Journal of Biological Chemistry 294:38, pages 14043-14054.
Crossref
A. O. Goncharov, A. A. Kliuchnikova, S. S. Nasaev & S. A. Moshkovskii. (2019) RNA Editing by ADAR Adenosine Deaminases: From Molecular Plasticity of Neural Proteins to the Mechanisms of Human Cancer. Biochemistry (Moscow) 84:8, pages 896-904.
Crossref
Alberto Bavelloni, Enrico Focaccia, Manuela Piazzi, Mirco Raffini, Valeriana Cesarini, Sara Tomaselli, Arianna Orsini, Stefano Ratti, Irene Faenza, Lucio Cocco, Angela Gallo & William L. Blalock. (2019) AKT‐dependent phosphorylation of the adenosine deaminases ADAR‐1 and ‐2 inhibits deaminase activity. The FASEB Journal 33:8, pages 9044-9061.
Crossref
Mart M. Lamers, Bernadette G. van den Hoogen & Bart L. Haagmans. (2019) ADAR1: “Editor-in-Chief” of Cytoplasmic Innate Immunity. Frontiers in Immunology 10.
Crossref
Manuela Piazzi, Alberto Bavelloni, Angela Gallo, Irene Faenza & William L. Blalock. (2019) Signal Transduction in Ribosome Biogenesis: A Recipe to Avoid Disaster. International Journal of Molecular Sciences 20:11, pages 2718.
Crossref
Kaori Nozaki, Masataka Nakano, Chika Iwakami, Tatsuki Fukami & Miki Nakajima. (2019) RNA Editing Enzymes Modulate the Expression of Hepatic CYP2B6, CYP2C8, and Other Cytochrome P450 Isoforms. Drug Metabolism and Disposition 47:6, pages 639-647.
Crossref
Alec L. W. Dick, Khen Khermesh, Evan Paul, Fabian Stamp, Erez Y. Levanon & Alon Chen. (2019) Adenosine-to-Inosine RNA Editing Within Corticolimbic Brain Regions Is Regulated in Response to Chronic Social Defeat Stress in Mice. Frontiers in Psychiatry 10.
Crossref
Genghao Chen, Dhruva Katrekar & Prashant Mali. (2019) RNA-Guided Adenosine Deaminases: Advances and Challenges for Therapeutic RNA Editing. Biochemistry 58:15, pages 1947-1957.
Crossref
Guan-Ru Liao, Yeu-Yang Tseng, Ching-Yu Tseng, Fong-Yuan Lin, Yumiko Yamada, Hao-Ping Liu, Chih-Ying Kuan & Wei-Li Hsu. (2019) Adenosine Deaminase Acting on RNA 1 Associates with Orf Virus OV20.0 and Enhances Viral Replication. Journal of Virology 93:7.
Crossref
Lisa E. Dorn, Simon Tual-Chalot, Konstantinos Stellos & Federica Accornero. (2019) RNA epigenetics and cardiovascular diseases. Journal of Molecular and Cellular Cardiology 129, pages 272-280.
Crossref
Shuvojit BanerjeeElona GushoChristina GaughanBeihua DongXiaorong GuElise Holvey-BatesManisha TalukdarYize Li, Susan R. WeissFrank Sicheri, Yogen SaunthararajahGeorge R. StarkRobert H. Silverman. (2019) OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug. Proceedings of the National Academy of Sciences 116:11, pages 5071-5076.
Crossref
Daniel P. Reich & Brenda L. Bass. (2019) Mapping the dsRNA World. Cold Spring Harbor Perspectives in Biology 11:3, pages a035352.
Crossref
Ketty Sinigaglia, Dagmara Wiatrek, Anzer Khan, David Michalik, Nagraj Sambrani, Jiří Sedmík, Dragana Vukić, Mary A. O'Connell & Liam P. Keegan. (2019) ADAR RNA editing in innate immune response phasing, in circadian clocks and in sleep. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862:3, pages 356-369.
Crossref
Kajsa Fritzell, Li-Di Xu, Magdalena Otrocka, Claes Andréasson & Marie Öhman. (2019) Sensitive ADAR editing reporter in cancer cells enables high-throughput screening of small molecule libraries. Nucleic Acids Research 47:4, pages e22-e22.
Crossref
Charles E. Samuel. (2019) Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA–triggered innate immune responses. Journal of Biological Chemistry 294:5, pages 1710-1720.
Crossref
Michihiro Kono & Masashi Akiyama. (2019) Dyschromatosis symmetrica hereditaria and reticulate acropigmentation of Kitamura: An update. Journal of Dermatological Science 93:2, pages 75-81.
Crossref
Paul Vogel & Thorsten Stafforst. (2019) Critical review on engineering deaminases for site-directed RNA editing. Current Opinion in Biotechnology 55, pages 74-80.
Crossref
Jeffrey J. Ishizuka, Robert T. Manguso, Collins K. Cheruiyot, Kevin Bi, Arpit Panda, Arvin Iracheta-Vellve, Brian C. Miller, Peter P. Du, Kathleen B. Yates, Juan Dubrot, Ilana Buchumenski, Dawn E. Comstock, Flavian D. Brown, Austin Ayer, Ian C. Kohnle, Hans W. Pope, Margaret D. Zimmer, Debattama R. Sen, Sarah K. Lane-Reticker, Emily J. Robitschek, Gabriel K. Griffin, Natalie B. Collins, Adrienne H. Long, John G. Doench, David Kozono, Erez Y. Levanon & W. Nicholas Haining. (2018) Loss of ADAR1 in tumours overcomes resistance to immune checkpoint blockade. Nature 565:7737, pages 43-48.
Crossref
Li-Di Xu & Marie Öhman. (2018) ADAR1 Editing and its Role in Cancer. Genes 10:1, pages 12.
Crossref
Hugh S. Gannon, Tao Zou, Michael K. Kiessling, Galen F. Gao, Diana Cai, Peter S. Choi, Alexandru P. Ivan, Ilana Buchumenski, Ashton C. Berger, Jonathan T. Goldstein, Andrew D. Cherniack, Francisca Vazquez, Aviad Tsherniak, Erez Y. Levanon, William C. Hahn & Matthew Meyerson. (2018) Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells. Nature Communications 9:1.
Crossref
Che-Pei Kung, Leonard B. MaggiJr.Jr. & Jason D. Weber. (2018) The Role of RNA Editing in Cancer Development and Metabolic Disorders. Frontiers in Endocrinology 9.
Crossref
Vito Carlo Alberto Caponio, Giuseppe Troiano, Gerardo Botti, Maria Carmela Pedicillo, Lucio Lo Russo, Filiberto Mastrangelo, Domenico Ciavarella, Nunzia Simona Losito, Gabriella Aquino, Riccardo Nocini, Rossella Santoro, Angela Santoro, Lorenzo Lo Muzio & Giuseppe Pannone. (2018) Overexpression of ADAR 1 into the cytoplasm correlates with a better prognosis of patients with oral squamous cells carcinoma . Journal of Oral Pathology & Medicine.
Crossref
Chi-Hua Lee, Yan-Ping Shih, Meng-Ru Ho & Andrew H-J Wang. (2018) The C-terminal D/E-rich domain of MBD3 is a putative Z-DNA mimic that competes for Zα DNA-binding activity. Nucleic Acids Research 46:22, pages 11806-11821.
Crossref
K. Pabbaraju, K. Fonseca, S. Wong, M. W. Koch, J. T. Joseph, G. A. Tipples & R. Tellier. (2018) Genetic characterization of measles virus genotype D6 subacute sclerosing panencephalitis case, Alberta, Canada. Journal of NeuroVirology 24:6, pages 720-729.
Crossref
Christian K. Pfaller, Ryan C. Donohue, Stepan Nersisyan, Leonid Brodsky & Roberto Cattaneo. (2018) Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1p150. PLOS Biology 16:11, pages e2006577.
Crossref
Aikaterini GatsiouNikolaos VlachogiannisFederica Francesca LunellaMarco SachseKonstantinos Stellos. (2018) Adenosine-to-Inosine RNA Editing in Health and Disease. Antioxidants & Redox Signaling 29:9, pages 846-863.
Crossref
Aikaterini GatsiouKonstantinos Stellos. (2018) Dawn of Epitranscriptomic Medicine. Circulation: Genomic and Precision Medicine 11:9.
Crossref
Raghuvaran Shanmugam, Fan Zhang, Harini Srinivasan, John Lalith Charles Richard, Kaiwen I Liu, Xiujun Zhang, Cheok Wei A Woo, Zi Hao M Chua, Jan Paul Buschdorf, Michael J Meaney & Meng How Tan. (2018) SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates. Nucleic Acids Research 46:14, pages 7379-7395.
Crossref
Eli Eisenberg & Erez Y. Levanon. (2018) A-to-I RNA editing — immune protector and transcriptome diversifier. Nature Reviews Genetics 19:8, pages 473-490.
Crossref
Kajsa Fritzell, Li-Di Xu, Jens Lagergren & Marie Öhman. (2018) ADARs and editing: The role of A-to-I RNA modification in cancer progression. Seminars in Cell & Developmental Biology 79, pages 123-130.
Crossref
Lea Shallev, Eli Kopel, Ariel Feiglin, Gil S. Leichner, Dror Avni, Yechezkel Sidi, Eli Eisenberg, Aviv Barzilai, Erez Y. Levanon & Shoshana Greenberger. (2018) Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis. RNA 24:6, pages 828-840.
Crossref
Ianis G. Matsoukas. (2018) Commentary: RNA editing with CRISPR-Cas13. Frontiers in Genetics 9.
Crossref
Roman Radetskyy, Aïcha Daher & Anne Gatignol. (2018) ADAR1 and PKR, interferon stimulated genes with clashing effects on HIV-1 replication. Cytokine & Growth Factor Reviews 40, pages 48-58.
Crossref
Dzwokai Ma, Cyril X. George, Jason L. Nomburg, Christian K. Pfaller, Roberto Cattaneo & Charles E. Samuel. (2018) Upon Infection, Cellular WD Repeat-Containing Protein 5 (WDR5) Localizes to Cytoplasmic Inclusion Bodies and Enhances Measles Virus Replication. Journal of Virology 92:5.
Crossref
Hao Lian, Qin-Hua Wang, Chang-Bin Zhu, Jie Ma & Wei-Lin Jin. (2018) Deciphering the Epitranscriptome in Cancer. Trends in Cancer 4:3, pages 207-221.
Crossref
Elisa Orecchini, Loredana Frassinelli, Silvia Galardi, Silvia Anna Ciafrè & Alessandro Michienzi. (2018) Post-transcriptional regulation of LINE-1 retrotransposition by AID/APOBEC and ADAR deaminases. Chromosome Research 26:1-2, pages 45-59.
Crossref
Alice Filippini, Daniela Bonini, Edoardo Giacopuzzi, Luca La Via, Fabrizio Gangemi, Marina Colombi & Alessandro Barbon. (2018) Differential Enzymatic Activity of Rat ADAR2 Splicing Variants Is Due to Altered Capability to Interact with RNA in the Deaminase Domain. Genes 9:2, pages 79.
Crossref
Zhuang-li TangShuang WangChen TuTian WangCheng-wen MaYan LiuSheng-xiang XiaoXiao-peng Wang. (2018) Eight Novel Mutations of the ADAR1 Gene in Chinese Patients with Dyschromatosis Symmetrica Hereditaria . Genetic Testing and Molecular Biomarkers 22:2, pages 104-108.
Crossref
V. Vongsutilers & P. M. Gannett. (2018) C8-Guanine modifications: effect on Z-DNA formation and its role in cancer. Organic & Biomolecular Chemistry 16:13, pages 2198-2209.
Crossref
Masataka Nakano & Miki Nakajima. (2018) Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics. Pharmacology & Therapeutics 181, pages 13-21.
Crossref
Ileana Lorenzini, Stephen Moore & Rita Sattler. 2018. RNA Metabolism in Neurodegenerative Diseases. RNA Metabolism in Neurodegenerative Diseases 63 83 .
Elisa Lazzari, Phoebe K. Mondala, Nathaniel Delos Santos, Amber C. Miller, Gabriel Pineda, Qingfei Jiang, Heather Leu, Shawn A. Ali, Anusha-Preethi Ganesan, Christina N. Wu, Caitlin Costello, Mark Minden, Raffaella Chiaramonte, A.  Keith Stewart, Leslie A. Crews & Catriona H. M. Jamieson. (2017) Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma. Nature Communications 8:1.
Crossref
Carl R. Walkley & Jin Billy Li. (2017) Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs. Genome Biology 18:1.
Crossref
Eddie Park, Jiguang Guo, Shihao Shen, Levon Demirdjian, Ying Nian Wu, Lan Lin & Yi Xing. (2017) Population and allelic variation of A-to-I RNA editing in human transcriptomes. Genome Biology 18:1.
Crossref
C Rossetti, E Picardi, M Ye, G Camilli, A M D'Erchia, L Cucina, F Locatelli, L Fianchi, L Teofili, G Pesole, A Gallo & R Sorrentino. (2017) RNA editing signature during myeloid leukemia cell differentiation. Leukemia 31:12, pages 2824-2832.
Crossref
Thirunavukkarasu Periyasamy, Joan Tang Xiao Joe & Ming-Wei Lu. (2017) Cloning and expression of Malabar grouper ( Epinephelus malabaricus ) ADAR1 gene in response to immune stimulants and nervous necrosis virus. Fish & Shellfish Immunology 71, pages 116-126.
Crossref
Chen Wang, Jun Zou, Xiangyi Ma, Edward Wang & Guang Peng. (2017) Mechanisms and implications of ADAR-mediated RNA editing in cancer. Cancer Letters 411, pages 27-34.
Crossref
Shuai-Mei Liu, Meng-Xia Ni, Ming-Chao Zhang, Pei-Ran Zhu, Qiu-Yu Wu, Wei-Jun Jiang, Jing Zhang, Wei-Wei Li & Xin-Yi Xia. (2017) A novel missense mutation of $$\textit{ADAR1}$$ ADAR 1 gene in a Chinese family leading to dyschromatosis symmetrica hereditaria and literature review. Journal of Genetics 96:6, pages 1021-1026.
Crossref
Arielle L. Yablonovitch, Patricia Deng, Dionna Jacobson & Jin Billy Li. (2017) The evolution and adaptation of A-to-I RNA editing. PLOS Genetics 13:11, pages e1007064.
Crossref
Konstantin Licht & Michael F. Jantsch. (2017) The Other Face of an Editor: ADAR1 Functions in Editing-Independent Ways. BioEssays 39:11, pages 1700129.
Crossref
Ji-Feng Feng, Sheng Chen & Xun Yang. (2017) Combination of c-reactive protein and squamous cell carcinoma antigen in predicting postoperative prognosis for patients with squamous cell carcinoma of the esophagus. Oncotarget 8:38, pages 63132-63139.
Crossref
Angela Gallo, Dragana Vukic, David Michalík, Mary A. O’Connell & Liam P. Keegan. (2017) ADAR RNA editing in human disease; more to it than meets the I. Human Genetics 136:9, pages 1265-1278.
Crossref
Jonathan M.O. Rawson, Daryl M. Gohl, Sean R. Landman, Megan E. Roth, Morgan E. Meissner, Tara S. Peterson, James S. Hodges, Kenneth B. Beckman & Louis M. Mansky. (2017) Single-Strand Consensus Sequencing Reveals that HIV Type but not Subtype Significantly Impacts Viral Mutation Frequencies and Spectra. Journal of Molecular Biology 429:15, pages 2290-2307.
Crossref
Masayuki Sakurai, Yusuke Shiromoto, Hiromitsu Ota, Chunzi Song, Andrew V Kossenkov, Jayamanna Wickramasinghe, Louise C Showe, Emmanuel Skordalakes, Hsin-Yao Tang, David W Speicher & Kazuko Nishikura. (2017) ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay. Nature Structural & Molecular Biology 24:6, pages 534-543.
Crossref
Nabeel S. Ganem, Noa Ben-Asher & Ayelet T. Lamm. (2017) In cancer, A-to-I RNA editing can be the driver, the passenger, or the mechanic. Drug Resistance Updates 32, pages 16-22.
Crossref
John T. CrowlElizabeth E. GrayKathleen PestalHannah E. VolkmanDaniel B. Stetson. (2017) Intracellular Nucleic Acid Detection in Autoimmunity. Annual Review of Immunology 35:1, pages 313-336.
Crossref
Charles Cho, Seung-Jae Myung & Suhwan Chang. (2017) ADAR1 and MicroRNA; A Hidden Crosstalk in Cancer. International Journal of Molecular Sciences 18:4, pages 799.
Crossref
Yize Li, Shuvojit Banerjee, Stephen A Goldstein, Beihua Dong, Christina Gaughan, Sneha Rath, Jesse Donovan, Alexei Korennykh, Robert H Silverman & Susan R Weiss. (2017) Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line. eLife 6.
Crossref
Nurit Gal-Mark, Lea Shallev, Sahar Sweetat, Michal Barak, Jin Billy Li, Erez Y. Levanon, Eli Eisenberg & Oded Behar. (2017) Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition. Scientific Reports 7:1.
Crossref
Eimile Oakes, Ashley Anderson, Aaron Cohen-Gadol & Heather A. Hundley. (2017) Adenosine Deaminase That Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma. Journal of Biological Chemistry 292:10, pages 4326-4335.
Crossref
Masataka Nakano, Tatsuki Fukami, Saki Gotoh & Miki Nakajima. (2017) A-to-I RNA Editing Up-regulates Human Dihydrofolate Reductase in Breast Cancer. Journal of Biological Chemistry 292:12, pages 4873-4884.
Crossref
Qingde Wang, Xiaoni Li, Ruofan Qi & Timothy Billiar. (2017) RNA Editing, ADAR1, and the Innate Immune Response. Genes 8:1, pages 41.
Crossref
Elisa Orecchini, Margherita Doria, Ambra Antonioni, Silvia Galardi, Silvia Anna Ciafrè, Loredana Frassinelli, Carmine Mancone, Claudia Montaldo, Marco Tripodi & Alessandro Michienzi. (2017) ADAR1 restricts LINE-1 retrotransposition. Nucleic Acids Research 45:1, pages 155-168.
Crossref
Yuru Wang, Yuxuan Zheng & Peter A. Beal. 2017. RNA Modification. RNA Modification 215 268 .
Ning Dou, Shijun Yu, Xiaojuan Ye, Dong Yang, Yandong Li & Yong Gao. (2016) Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling. Oncotarget 7:52, pages 86161-86173.
Crossref
Chunzi Song, Masayuki Sakurai, Yusuke Shiromoto & Kazuko Nishikura. (2016) Functions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human Diseases. Genes 7:12, pages 129.
Crossref
Melanie A. Huntley, Melanie Lou, Leonard D. Goldstein, Michael Lawrence, Gerrit J.P. Dijkgraaf, Joshua S. Kaminker & Robert Gentleman. (2016) Complex regulation of ADAR-mediated RNA-editing across tissues. BMC Genomics 17:1.
Crossref
Ning Dong, Chunsheng Dong & Sidong Xiong. (2016) Janus effects of ADAR1 on CVB3-induced viral myocarditis at different infection stages. International Journal of Cardiology 223, pages 898-905.
Crossref
Brian J. Liddicoat, Jochen C. Hartner, Robert Piskol, Gokul Ramaswami, Alistair M. Chalk, Paul D. Kingsley, Vijay G. Sankaran, Meaghan Wall, Louise E. Purton, Peter H. Seeburg, James Palis, Stuart H. Orkin, Jun Lu, Jin Billy Li & Carl R. Walkley. (2016) Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis. Experimental Hematology 44:10, pages 947-963.
Crossref
Xiancheng Liu, Keyi Huang, Qunhao Hou, Zhicheng Sun, Binhua Wang, Gang Lin, Dongming Li, Yong Liu, Xiaowen Xu & Chengyu Hu. (2016) Identification and characterization of a constitutively expressed Ctenopharyngodon idella ADAR1 splicing isoform (CiADAR1a). Developmental & Comparative Immunology 63, pages 10-17.
Crossref
Jacki E. Heraud-Farlow & Carl R. Walkley. (2016) The role of RNA editing by ADAR1 in prevention of innate immune sensing of self-RNA. Journal of Molecular Medicine 94:10, pages 1095-1102.
Crossref
D Weissmann, S van der Laan, M D Underwood, N Salvetat, L Cavarec, L Vincent, F Molina, J J Mann, V Arango & J F Pujol. (2016) Region-specific alterations of A-to-I RNA editing of serotonin 2c receptor in the cortex of suicides with major depression. Translational Psychiatry 6:8, pages e878-e878.
Crossref
Wei Chen, Dong An, Hong Xu, Xiaoxin Cheng, Shiwei Wang, Weizhi Yu, Deqin Yu, Dan Zhao, Yiping Sun, Wuguo Deng, Yiyuan Tang & Shengming Yin. (2016) Effects of social isolation and re-socialization on cognition and ADAR1 (p110) expression in mice. PeerJ 4, pages e2306.
Crossref
Cyril X. George, Gokul Ramaswami, Jin Billy Li & Charles E. Samuel. (2016) Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses. Journal of Biological Chemistry 291:12, pages 6158-6168.
Crossref
Mansoureh Tajaddod, Michael F. Jantsch & Konstantin Licht. (2015) The dynamic epitranscriptome: A to I editing modulates genetic information. Chromosoma 125:1, pages 51-63.
Crossref
Brian J. Liddicoat, Alistair M. Chalk & Carl R. Walkley. (2015) ADAR1 , inosine and the immune sensing system: distinguishing self from non‐self . WIREs RNA 7:2, pages 157-172.
Crossref
Kiranmai Gumireddy, Anping Li, Andrew V. Kossenkov, Masayuki Sakurai, Jinchun Yan, Yan Li, Hua Xu, Jian Wang, Paul J. Zhang, Lin Zhang, Louise C. Showe, Kazuko Nishikura & Qihong Huang. (2016) The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis. Nature Communications 7:1.
Crossref
Khen Khermesh, Anna Maria D'Erchia, Michal Barak, Anita Annese, Chaim Wachtel, Erez Y. Levanon, Ernesto Picardi & Eli Eisenberg. (2016) Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease. RNA 22:2, pages 290-302.
Crossref
Kazuko Nishikura. (2015) A-to-I editing of coding and non-coding RNAs by ADARs. Nature Reviews Molecular Cell Biology 17:2, pages 83-96.
Crossref
Masataka Nakano, Tatsuki Fukami, Saki Gotoh, Masataka Takamiya, Yasuhiro Aoki & Miki Nakajima. (2016) RNA Editing Modulates Human Hepatic Aryl Hydrocarbon Receptor Expression by Creating MicroRNA Recognition Sequence. Journal of Biological Chemistry 291:2, pages 894-903.
Crossref
Sarah N. Deffit & Heather A. Hundley. (2015) To edit or not to edit: regulation of ADAR editing specificity and efficiency . WIREs RNA 7:1, pages 113-127.
Crossref
Adi Shamay-Ramot, Khen Khermesh, Hagit T. Porath, Michal Barak, Yishay Pinto, Chaim Wachtel, Alona Zilberberg, Tali Lerer-Goldshtein, Sol Efroni, Erez Y. Levanon & Lior Appelbaum. (2015) Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish. PLOS Genetics 11:12, pages e1005702.
Crossref
Cyril X. George & Charles E. Samuel. (2015) STAT2-dependent induction of RNA adenosine deaminase ADAR1 by type I interferon differs between mouse and human cells in the requirement for STAT1. Virology 485, pages 363-370.
Crossref
Elisa Orecchini, Maurizio Federico, Margherita Doria, Claudia Arenaccio, Erica Giuliani, Silvia Anna Ciafrè & Alessandro Michienzi. (2015) The ADAR1 editing enzyme is encapsidated into HIV-1 virions. Virology 485, pages 475-480.
Crossref
Binhua Wang, Yong Liu, Zhicheng Sun, Xiancheng Liu, Yichuan Mi, Dan Liu, Xiaowen Xu, Qunhao Hou, Fang Wang & Chengyu Hu. (2015) A splicing isoform of Ctenopharyngodon idella ADAR1 ( CiADAR1-like ): Genome organization, tissue specific expression and transcriptional regulation. Fish & Shellfish Immunology 47:1, pages 535-544.
Crossref
Bin Yang, Peishan Hu, Xihua Lin, Wei Han, Liyuan Zhu, Xiaochao Tan, Fei Ye, Guanzhou Wang, Fan Wu, Bin Yin, Zhaoshi Bao, Tao Jiang, Jiangang Yuan, Boqin Qiang & Xiaozhong Peng. (2015) PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas. Cellular and Molecular Life Sciences 72:22, pages 4383-4397.
Crossref

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