Citations (375)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (12)
Amina El Ayadi, Emily S. Stieren, José M. Barral & Darren Boehning. (2013) Ubiquilin-1 and protein quality control in Alzheimer disease. Prion 7:2, pages 164-169.
Read now
Read now
Amanda H. Caster & Richard A. Kahn. (2012) Computational method for calculating fluorescence intensities within three-dimensional structures in cells. Cellular Logistics 2:4, pages 176-188.
Read now
Read now
Matthew J. Smith, W. Rod Hardy, James M. Murphy, Nina Jones & Tony Pawson. (2006) Screening for PTB Domain Binding Partners and Ligand Specificity Using Proteome-Derived NPXY Peptide Arrays. Molecular and Cellular Biology 26:22, pages 8461-8474.
Read now
Read now
Keun-A Chang, Hye-Sun Kim, Tae-Young Ha, Ji-Won Ha, Ki Young Shin, Yun Ha Jeong, Jean-Pyo Lee, Cheol-Hyoung Park, Seonghan Kim, Tae-Kyoung Baik & Yoo-Hun Suh. (2006) Phosphorylation of Amyloid Precursor Protein (APP) at Thr668 Regulates the Nuclear Translocation of the APP Intracellular Domain and Induces Neurodegeneration. Molecular and Cellular Biology 26:11, pages 4327-4338.
Read now
Read now
Annalisa LAMBERTI, Olimpia LONGO, Pompea Del VECCHIO, Nicola ZAMBRANO, Guido BARONE, Tommaso RUSSO & Paolo ARCARI. (2005) Probing the Secondary Structure of a Recombinant Neuronal Adaptor Protein and Its Phosphotyrosine Binding Domains. Bioscience, Biotechnology, and Biochemistry 69:12, pages 2395-2400.
Read now
Read now
Nina Jones, Stephen H. Chen, Celina Sturk, Zubin Master, Jennifer Tran, Robert S. Kerbel & Daniel J. Dumont. (2003) A Unique Autophosphorylation Site on Tie2/Tek Mediates Dok-R Phosphotyrosine Binding Domain Binding and Function. Molecular and Cellular Biology 23:8, pages 2658-2668.
Read now
Read now
S. H. Ong, G. R. Guy, Y. R. Hadari, S. Laks, N. Gotoh, J. Schlessinger & I. Lax. (2000) FRS2 Proteins Recruit Intracellular Signaling Pathways by Binding to Diverse Targets on Fibroblast Growth Factor and Nerve Growth Factor Receptors. Molecular and Cellular Biology 20:3, pages 979-989.
Read now
Read now
Brian W. Howell, Lorene M. Lanier, Ronald Frank, Frank B. Gertler & Jonathan A. Cooper. (1999) The Disabled 1 Phosphotyrosine-Binding Domain Binds to the Internalization Signals of Transmembrane Glycoproteins and to Phospholipids. Molecular and Cellular Biology 19:7, pages 5179-5188.
Read now
Read now
Qingshen Gao, Seetha Srinivasan, Sarah N. Boyer, David E. Wazer & Vimla Band. (1999) The E6 Oncoproteins of High-Risk Papillomaviruses Bind to a Novel Putative GAP Protein, E6TP1, and Target It for Degradation. Molecular and Cellular Biology 19:1, pages 733-744.
Read now
Read now
Ngocdiep Le & Michael A. Simon. (1998) Disabled Is a Putative Adaptor Protein That Functions during Signaling by the Sevenless Receptor Tyrosine Kinase. Molecular and Cellular Biology 18:8, pages 4844-4854.
Read now
Read now
Cheng-ting Chien, Shuwen Wang, Michael Rothenberg, Lily Y. Jan & Yuh Nung Jan. (1998) Numb-Associated Kinase Interacts with the Phosphotyrosine Binding Domain of Numb and Antagonizes the Function of Numb In Vivo. Molecular and Cellular Biology 18:1, pages 598-607.
Read now
Read now
Liangyou Rui, Lawrence S. Mathews, Kikuko Hotta, Thomas A. Gustafson & Christin Carter-Su. (1997) Identification of SH2-Bβ as a Substrate of the Tyrosine Kinase JAK2 Involved in Growth Hormone Signaling. Molecular and Cellular Biology 17:11, pages 6633-6644.
Read now
Read now
Articles from other publishers (363)
Raffaella Barbieri, Mario Nizzari, Ilaria Zanardi, Michael Pusch & Paola Gavazzo. (2023) Voltage-Gated Sodium Channel Dysfunctions in Neurological Disorders. Life 13:5, pages 1191.
Crossref
Crossref
Renato Brandimarti, Elena Irollo & Olimpia Meucci. (2022) The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities. Molecular Neurobiology 60:4, pages 1811-1825.
Crossref
Crossref
Joana Rajão‐Saraiva, Jade Dunot, Aurore Ribera, Mariana Temido‐Ferreira, Joana E. Coelho, Svenja König, Sébastien Moreno, Francisco J. Enguita, Michael Willem, Stefan Kins, Hélène Marie, Luísa V. Lopes & Paula A. Pousinha. (2023) Age‐dependent NMDA receptor function is regulated by the amyloid precursor protein. Aging Cell 22:3.
Crossref
Crossref
Christian R. O. Bartling, Flora Alexopoulou, Sarah Kuschert, Yanni K.-Y. Chin, Xinying Jia, Vita Sereikaite, Dennis Özcelik, Thomas M. Jensen, Palash Jain, Mads M. Nygaard, Kasper Harpsøe, David E. Gloriam, Mehdi Mobli & Kristian Strømgaard. (2023) Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2. Journal of Medicinal Chemistry 66:4, pages 3045-3057.
Crossref
Crossref
Noritaka Tanaka & Takeharu Sakamoto. (2023) Mint3 as a Potential Target for Cooling Down HIF-1α-Mediated Inflammation and Cancer Aggressiveness. Biomedicines 11:2, pages 549.
Crossref
Crossref
Carmela Matrone. (2023) The paradigm of amyloid precursor protein in amyotrophic lateral sclerosis: The potential role of the 682YENPTY687 motif. Computational and Structural Biotechnology Journal 21, pages 923-930.
Crossref
Crossref
Daniela Passarella, Silvia Ciampi, Valentina Di Liberto, Mariachiara Zuccarini, Maurizio Ronci, Alessandro Medoro, Emanuele Foderà, Monica Frinchi, Donatella Mignogna, Claudio Russo & Carola Porcile. (2022) Low-Density Lipoprotein Receptor-Related Protein 8 at the Crossroad between Cancer and Neurodegeneration. International Journal of Molecular Sciences 23:16, pages 8921.
Crossref
Crossref
Grant Pfundstein, Alexander G. Nikonenko & Vladimir Sytnyk. (2022) Amyloid precursor protein (APP) and amyloid β (Aβ) interact with cell adhesion molecules: Implications in Alzheimer’s disease and normal physiology. Frontiers in Cell and Developmental Biology 10.
Crossref
Crossref
Yoonsuk Cho, Han-Gyu Bae, Eitan Okun, Thiruma V. Arumugam & Dong-Gyu Jo. (2022) Physiology and pharmacology of amyloid precursor protein. Pharmacology & Therapeutics 235, pages 108122.
Crossref
Crossref
Rebecca M. C. Gabriele, Emily Abel, Nick C. Fox, Selina Wray & Charles Arber. (2022) Knockdown of Amyloid Precursor Protein: Biological Consequences and Clinical Opportunities. Frontiers in Neuroscience 16.
Crossref
Crossref
Stefan J. Hermans, Tracy L. Nero, Craig J. Morton, Jonathan H. Gooi, Gabriela A. N. Crespi, Nancy C. Hancock, Chen Gao, Kenta Ishii, Jasmina Markulić & Michael W. Parker. (2021) Structural biology of cell surface receptors implicated in Alzheimer’s disease. Biophysical Reviews 14:1, pages 233-255.
Crossref
Crossref
Junyao Xu, Erina Iwabuchi, Yasuhiro Miki, Ayako Kanai, Takanori Ishida & Hironobu Sasano. (2021) FE65 in breast cancer and its clinicopathological significance. Breast Cancer 29:1, pages 144-155.
Crossref
Crossref
Caterina Nardella, Lorenzo Visconti, Francesca Malagrinò, Livia Pagano, Marianna Bufano, Marianna Nalli, Antonio Coluccia, Giuseppe La Regina, Romano Silvestri, Stefano Gianni & Angelo Toto. (2021) Targeting PDZ domains as potential treatment for viral infections, neurodegeneration and cancer. Biology Direct 16:1.
Crossref
Crossref
Xi-Jun Song, He-Yan Zhou, Yu-Ying Sun & Han-Chang Huang. (2021) Phosphorylation and Glycosylation of Amyloid-β Protein Precursor: The Relationship to Trafficking and Cleavage in Alzheimer’s Disease. Journal of Alzheimer's Disease 84:3, pages 937-957.
Crossref
Crossref
Akhil Padarti, Johnathan Abou-Fadel & Jun Zhang. (2021) Resurgence of phosphotyrosine binding domains: Structural and functional properties essential for understanding disease pathogenesis. Biochimica et Biophysica Acta (BBA) - General Subjects 1865:11, pages 129977.
Crossref
Crossref
Vanessa Augustin & Stefan Kins. (2021) Fe65: A Scaffolding Protein of Actin Regulators. Cells 10:7, pages 1599.
Crossref
Crossref
Kaushik Chanda, Sayantan Laha, Raghunath Chatterjee & Debashis Mukhopadhyay. (2021) Amyloid precursor protein intra-cellular domain (AICD), Aβ and their confounding synergistic effects differentially regulate the degradome of cellular models of Alzheimer's disease. Gene Reports 23, pages 101082.
Crossref
Crossref
Christian R. O. Bartling, Thomas M. T. Jensen, Shawna M. Henry, Anna L. Colliander, Vita Sereikaite, Marcella Wenzler, Palash Jain, Hans M. Maric, Kasper Harpsøe, Søren W. Pedersen, Louise S. Clemmensen, Linda M. Haugaard-Kedström, David E. Gloriam, Angela Ho & Kristian Strømgaard. (2021) Targeting the APP-Mint2 Protein–Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid-β Formation. Journal of the American Chemical Society 143:2, pages 891-901.
Crossref
Crossref
Sabine Probst, Maik Krüger, Larissa Kägi, Sarina Thöni, Daniel Schuppli, Roger M. Nitsch & Uwe Konietzko. (2020) Fe65 is the sole family member mediating transcription regulated by the amyloid precursor protein. Journal of Cell Science.
Crossref
Crossref
Gábor M. Mórotz, Elizabeth B. Glennon, Jenny Greig, Dawn H. W. Lau, Nishita Bhembre, Francesca Mattedi, Nadine Muschalik, Wendy Noble, Alessio Vagnoni & Christopher C. J. Miller. (2019) Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer’s disease and regulates axonal transport and processing of the amyloid precursor protein. Acta Neuropathologica Communications 7:1.
Crossref
Crossref
Dennis Dik‐Long Chau, Kristen Wing‐Yu Yung, William Wai‐Lun Chan, Ying An, Yan Hao, Ho‐Yin Edwin Chan, Jacky Chi‐Ki Ngo & Kwok‐Fai Lau. (2019) Attenuation of amyloid‐β generation by atypical protein kinase C‐mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35. The FASEB Journal 33:11, pages 12019-12035.
Crossref
Crossref
Uwe Konietzko, Manuel T. Gersbacher, Jeremy Streuli, Maik Krüger, Sarina Thöni, Stefan Kins & Roger M. Nitsch. (2019) A fluorescent protein-readout for transcriptional activity reveals regulation of APP nuclear signaling by phosphorylation sites. Biological Chemistry 400:9, pages 1191-1203.
Crossref
Crossref
Melike Yuksel & Ozden Tacal. (2019) Trafficking and proteolytic processing of amyloid precursor protein and secretases in Alzheimer's disease development: An up-to-date review. European Journal of Pharmacology 856, pages 172415.
Crossref
Crossref
Lisa Merthan, Amelie Haller, Dietmar R. Thal, Bjoern von Einem & Christine A.F. von Arnim. (2019) The role of PTB domain containing adaptor proteins on PICALM-mediated APP endocytosis and localization. Biochemical Journal 476:14, pages 2093-2109.
Crossref
Crossref
Carmela Matrone, Filomena Iannuzzi & Lucio Annunziato. (2019) The Y682ENPTY687 motif of APP: Progress and insights toward a targeted therapy for Alzheimer’s disease patients. Ageing Research Reviews 52, pages 120-128.
Crossref
Crossref
Nikolaj R. Christensen, Jelena Čalyševa, Eduardo F. A. Fernandes, Susanne Lüchow, Louise S. Clemmensen, Linda M. Haugaard‐Kedström & Kristian Strømgaard. (2019) PDZ Domains as Drug Targets. Advanced Therapeutics, pages 1800143.
Crossref
Crossref
Amy Y. Lin, Shawna Henry, Carsten Reissner, Christian Neupert, Connor Kenny, Markus Missler, Uwe Beffert & Angela Ho. (2019) A rare autism-associated MINT2/APBA2 mutation disrupts neurexin trafficking and synaptic function. Scientific Reports 9:1.
Crossref
Crossref
Jing Zhi A. Tan & Paul A. Gleeson. (2019) The role of membrane trafficking in the processing of amyloid precursor protein and production of amyloid peptides in Alzheimer's disease. Biochimica et Biophysica Acta (BBA) - Biomembranes 1861:4, pages 697-712.
Crossref
Crossref
Jing Zhi A. Tan & Paul A. Gleeson. (2019) The trans-Golgi network is a major site for α-secretase processing of amyloid precursor protein in primary neurons. Journal of Biological Chemistry 294:5, pages 1618-1631.
Crossref
Crossref
Noralyn Basco Mañucat-Tan, Khalil Saadipour, Yan-Jiang Wang, Larisa Bobrovskaya & Xin-Fu Zhou. (2018) Cellular Trafficking of Amyloid Precursor Protein in Amyloidogenesis Physiological and Pathological Significance. Molecular Neurobiology 56:2, pages 812-830.
Crossref
Crossref
Thomas M. T. Jensen, Louise Albertsen, Christian R. O. Bartling, Linda M. Haugaard-Kedström & Kristian Strømgaard. (2018) Probing the Mint2 Protein-Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease. ChemBioChem 19:11, pages 1119-1122.
Crossref
Crossref
Jichao Sun & Subhojit Roy. (2018) The physical approximation of APP and BACE-1: A key event in alzheimer's disease pathogenesis. Developmental Neurobiology 78:3, pages 340-347.
Crossref
Crossref
Christine Salaun, Louise Ritchie, Jennifer Greaves, Trevor J. Bushell & Luke H. Chamberlain. (2017) The C-terminal domain of zDHHC2 contains distinct sorting signals that regulate intracellular localisation in neurons and neuroendocrine cells. Molecular and Cellular Neuroscience 85, pages 235-246.
Crossref
Crossref
Lucas J. Sosa, Alfredo Cáceres, Sebastián Dupraz, Mariana Oksdath, Santiago Quiroga & Alfredo Lorenzo. (2017) The physiological role of the amyloid precursor protein as an adhesion molecule in the developing nervous system. Journal of Neurochemistry 143:1, pages 11-29.
Crossref
Crossref
Jessica Santana & María-Paz Marzolo. (2017) The functions of Reelin in membrane trafficking and cytoskeletal dynamics: implications for neuronal migration, polarization and differentiation. Biochemical Journal 474:18, pages 3137-3165.
Crossref
Crossref
Hassan Bukhari, Annika Glotzbach, Katharina Kolbe, Gregor Leonhardt, Christina Loosse & Thorsten Müller. (2017) Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer’s disease. Progress in Neurobiology 156, pages 189-213.
Crossref
Crossref
Loreto Carvallo, Lillie Lopez, Jorge E. Fajardo, Matias Jaureguiberry-Bravo, Andras Fiser & Joan W. Berman. (2017) HIV-Tat regulates macrophage gene expression in the context of neuroAIDS. PLOS ONE 12:6, pages e0179882.
Crossref
Crossref
Lukas P. Feilen, Kevin Haubrich, Paul Strecker, Sabine Probst, Simone Eggert, Gunter Stier, Irmgard Sinning, Uwe Konietzko, Stefan Kins, Bernd Simon & Klemens Wild. (2017) Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction. Frontiers in Molecular Neuroscience 10.
Crossref
Crossref
Baiping Wang, Hongmei Li, Sena A. Mutlu, Devon A. Bowser, Michael J. Moore, Meng C. Wang & Hui Zheng. (2017) The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance. eneuro 4:3, pages ENEURO.0185-17.2017.
Crossref
Crossref
Suzanne Guénette, Paul Strecker & Stefan Kins. (2017) APP Protein Family Signaling at the Synapse: Insights from Intracellular APP-Binding Proteins. Frontiers in Molecular Neuroscience 10.
Crossref
Crossref
Niina A. Koistinen, Anna K. Edlund, Preeti K. Menon, Elena V. Ivanova, Smaranda Bacanu & Kerstin Iverfeldt. (2017) Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis. PLOS ONE 12:3, pages e0173888.
Crossref
Crossref
Kendra L. Puig, Stephen A. Brose, Xudong Zhou, Mary A. Sens, Gerald F. Combs, Michael D. Jensen, Mikhail Y. Golovko & Colin K. Combs. (2017) Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain. Scientific Reports 7:1.
Crossref
Crossref
Theresa Pohlkamp, Catherine R. Wasser & Joachim Herz. (2017) Functional Roles of the Interaction of APP and Lipoprotein Receptors. Frontiers in Molecular Neuroscience 10.
Crossref
Crossref
Wei Hong Toh, Jing Zhi A. Tan, Khalisah L. Zulkefli, Fiona J. Houghton & Paul A. Gleeson. (2017) Amyloid precursor protein traffics from the Golgi directly to early endosomes in an Arl5b- and AP4-dependent pathway. Traffic 18:3, pages 159-175.
Crossref
Crossref
Catherine R. Wasser & Joachim Herz. (2017) Reelin: Neurodevelopmental Architect and Homeostatic Regulator of Excitatory Synapses. Journal of Biological Chemistry 292:4, pages 1330-1338.
Crossref
Crossref
Rika Motodate, Yuhki Saito, Saori Hata & Toshiharu Suzuki. (2016) Expression and localization of X11 family proteins in neurons. Brain Research 1646, pages 227-234.
Crossref
Crossref
Dolores Del Prete, Richard C. Rice, Anjali M. Rajadhyaksha & Luciano D'Adamio. (2016) Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4CRBN and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Functions and Neurodegeneration. Journal of Biological Chemistry 291:33, pages 17209-17227.
Crossref
Crossref
Christopher J. R. Dunning, Hannah L. Black, Katie L. Andrews, Elizabeth C. Davenport, Michael Conboy, Sangeeta Chawla, Adam A. Dowle, David Ashford, Jerry R. Thomas & Gareth J. O. Evans. (2016) Multisite tyrosine phosphorylation of the N-terminus of Mint1/X11α by Src kinase regulates the trafficking of amyloid precursor protein. Journal of Neurochemistry 137:4, pages 518-527.
Crossref
Crossref
S Kim, Y Sato, P S Mohan, C Peterhoff, A Pensalfini, A Rigoglioso, Y Jiang & R A Nixon. (2015) Evidence that the rab5 effector APPL1 mediates APP-βCTF-induced dysfunction of endosomes in Down syndrome and Alzheimer’s disease. Molecular Psychiatry 21:5, pages 707-716.
Crossref
Crossref
Mei-Chen Liao, Christina R. Muratore, Todd M. Gierahn, Sarah E. Sullivan, Priya Srikanth, Philip L. De Jager, J. Christopher Love & Tracy L. Young-Pearse. (2016) Single-Cell Detection of Secreted Aβ and sAPPα from Human IPSC-Derived Neurons and Astrocytes. The Journal of Neuroscience 36:5, pages 1730-1746.
Crossref
Crossref
Niina A. Koistinen, Smaranda Bacanu & Kerstin Iverfeldt. (2016) Phosphorylation of Fe65 amyloid precursor protein-binding protein in response to neuronal differentiation. Neuroscience Letters 613, pages 54-59.
Crossref
Crossref
Jack O'Sullivan, Emma Comerford, Walid Rachidi, Michael Scott, Nigel M. Hooper & Hilary E.M. McMahon. (2015) The effects of the cellular and infectious prion protein on the neuronal adaptor protein X11α. Biochimica et Biophysica Acta (BBA) - General Subjects 1850:11, pages 2213-2221.
Crossref
Crossref
Paul A. JowseyPeter G. Blain. (2015) Fe65 Ser228 is phosphorylated by ATM/ATR and inhibits Fe65–APP-mediated gene transcription. Biochemical Journal 465:3, pages 413-421.
Crossref
Crossref
Wan Ning Vanessa Chow, Hei Nga Maggie Cheung, Wen Li & Kwok-Fai Lau. (2015) FE65: Roles beyond amyloid precursor protein processing. Cellular and Molecular Biology Letters 20:1.
Crossref
Crossref
Marie Decock, Laetitia El Haylani, Serena Stanga, Ilse Dewachter, Jean-Noël Octave, Steven O. Smith, Stefan N. Constantinescu & Pascal Kienlen-Campard. (2015) Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing. FEBS Open Bio 5:1, pages 763-773.
Crossref
Crossref
Dolores Del Prete, Franco Lombino, Xinran Liu & Luciano D'Adamio. (2014) APP Is Cleaved by Bace1 in Pre-Synaptic Vesicles and Establishes a Pre-Synaptic Interactome, via Its Intracellular Domain, with Molecular Complexes that Regulate Pre-Synaptic Vesicles Functions. PLoS ONE 9:9, pages e108576.
Crossref
Crossref
Ina Coburger, Sandra Hoefgen & Manuel E. Than. (2014) The structural biology of the amyloid precursor protein APP – a complex puzzle reveals its multi-domain architecture. Biological Chemistry 395:5, pages 485-498.
Crossref
Crossref
Sarah E. Sullivan, Gregory M. Dillon, Josefa M. Sullivan & Angela Ho. (2014) Mint Proteins Are Required for Synaptic Activity-dependent Amyloid Precursor Protein (APP) Trafficking and Amyloid β Generation. Journal of Biological Chemistry 289:22, pages 15374-15383.
Crossref
Crossref
Jing Wang, Ke Yan, Zhi-Qiang Wu, Chuan-Yi Zheng, Ru-Xiang Xu, Li-Hua Chen, Zhong-Min Wen, He-Qing Zhao & Quan-Hong Ma. (2014) TDP-43 interaction with the intracellular domain of amyloid precursor protein induces p53-associated apoptosis. Neuroscience Letters 569, pages 131-136.
Crossref
Crossref
Christine Villegas, Virgil Muresan & Zoia Ladescu Muresan. (2014) Dual-tagged amyloid-β precursor protein reveals distinct transport pathways of its N- and C-terminal fragments. Human Molecular Genetics 23:6, pages 1631-1643.
Crossref
Crossref
Fabian M. Nensa, Martin H.D. Neumann, Andreas Schrötter, Andre Przyborski, Thomas Mastalski, Sergej Susdalzew, Christina Looβe, Stefan Helling, Fouzi El Magraoui, Ralf Erdmann, Helmut E. Meyer, Julian Uszkoreit, Martin Eisenacher, Jaehong Suh, Suzanne Y. Guénette, Nelli Röhner, Donat Kögel, Carsten Theiss, Katrin Marcus & Thorsten Müller. (2014) Amyloid Beta A4 Precursor Protein-binding Family B Member 1 (FE65) Interactomics Revealed Synaptic Vesicle Glycoprotein 2A (SV2A) and Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2 (SERCA2) as New Binding Proteins in the Human Brain. Molecular & Cellular Proteomics 13:2, pages 475-488.
Crossref
Crossref
Hei Nga Maggie Cheung, Charlotte Dunbar, Gábor M. Mórotz, Wai Hang Cheng, Ho Yin Edwin Chan, Christopher C. J. Miller & Kwok‐Fai Lau. (2013) FE65 interacts with ADP‐ribosylation factor 6 to promote neurite outgrowth. The FASEB Journal 28:1, pages 337-349.
Crossref
Crossref
Jingjing Wang, Chunyan Shan, Wenyuan Cao, Chen Zhang, Junlin Teng & Jianguo Chen. (2013) SCG10 promotes non-amyloidogenic processing of amyloid precursor protein by facilitating its trafficking to the cell surface. Human Molecular Genetics 22:24, pages 4888-4900.
Crossref
Crossref
Stefano Musardo, Claudia Saraceno, Silvia Pelucchi & Elena Marcello. (2013) Trafficking in neurons: Searching for new targets for Alzheimer's disease future therapies. European Journal of Pharmacology 719:1-3, pages 84-106.
Crossref
Crossref
Amanda H. Caster & Richard A. Kahn. (2013) Recruitment of the Mint3 Adaptor Is Necessary for Export of the Amyloid Precursor Protein (APP) from the Golgi Complex. Journal of Biological Chemistry 288:40, pages 28567-28580.
Crossref
Crossref
Jayalal L.P. Merlin. (2013) Electrophysiological Functions of Intracellular Amyloid β in Specific for Cultured Human Neurones and its Impairment Properties. Journal of the Chosun Natural Science 6:3, pages 143-150.
Crossref
Crossref
Pamela Farfán, Jiyeon Lee, Jorge Larios, Pablo Sotelo, Guojun Bu & María-Paz Marzolo. (2013) A Sorting Nexin 17-Binding Domain Within the LRP1 Cytoplasmic Tail Mediates Receptor Recycling Through the Basolateral Sorting Endosome. Traffic 14:7, pages 823-838.
Crossref
Crossref
Anika Thyrock, Edith Ossendorf, Martin Stehling, Mark Kail, Tanja Kurtz, Gottfried Pohlentz, Dieter Waschbüsch, Simone Eggert, Etienne Formstecher, Johannes Müthing, Klaus Dreisewerd, Stefan Kins, Bruno Goud & Angelika Barnekow. (2013) A New Mint1 Isoform, but Not the Conventional Mint1, Interacts with the Small GTPase Rab6. PLoS ONE 8:5, pages e64149.
Crossref
Crossref
Miao Yang, Balaji Virassamy, Swarna Lekha Vijayaraj, Yoon Lim, Khalil Saadipour, Yan-Jiang Wang, Yan-Chuang Han, Jin-Hua Zhong, Carlos R. Morales & Xin-Fu Zhou. (2013) The Intracellular Domain of Sortilin Interacts with Amyloid Precursor Protein and Regulates Its Lysosomal and Lipid Raft Trafficking. PLoS ONE 8:5, pages e63049.
Crossref
Crossref
Garrett G. Gross, G. Mohiddin Lone, Lok Kwan Leung, Volker Hartenstein & Ming Guo. (2013)
X11/Mint
Genes Control Polarized Localization of Axonal Membrane Proteins
in Vivo
. The Journal of Neuroscience 33:19, pages 8575-8586.
Crossref
Crossref
Amanda H. Caster, Elizabeth Sztul & Richard A. Kahn. (2013) A Role for Cargo in Arf-dependent Adaptor Recruitment. Journal of Biological Chemistry 288:21, pages 14788-14804.
Crossref
Crossref
Anke Wahler, Anja-Silke Beyer, Ilona E. Keller, Cathrin Schnack, Björn von Einem, Christian Pröpper, Tobias M. Boeckers, Ithan D. PeltanDudley K. StricklandBradley T. HymanChristine A. F. von Arnim. (2013) Engulfment adaptor phosphotyrosine-binding-domain-containing 1 (GULP1) is a nucleocytoplasmic shuttling protein and is transactivationally active together with low-density lipoprotein receptor-related protein 1 (LRP1). Biochemical Journal 450:2, pages 333-343.
Crossref
Crossref
Sonya B Dumanis, Kelly A Chamberlain, Yoo Jin Sohn, Young Jin Lee, Suzanne Y Guénette, Toshiharu Suzuki, Paul M Mathews, Daniel TS Pak, G William Rebeck, Yoo-hun Suh, Hee-Sae Park & Hyang-Sook Hoe. (2012) FE65 as a link between VLDLR and APP to regulate their trafficking and processing. Molecular Neurodegeneration 7:1.
Crossref
Crossref
Byungkyu Park, Wook Lee & Kyungsook Han. (2012) Modeling the interactions of Alzheimer-related genes from the whole brain microarray data and diffusion tensor images of human brain. BMC Bioinformatics 13:S7.
Crossref
Crossref
Han Zhang, Yun-wu Zhang, Yaomin Chen, Xiumei Huang, Fangfang Zhou, Weiwei Wang, Bo Xian, Xian Zhang, Eliezer Masliah, Quan Chen, Jing-Dong J. Han, Guojun Bu, John C. Reed, Francesca-Fang Liao, Ye-Guang Chen & Huaxi Xu. (2012) Appoptosin is a Novel Pro-Apoptotic Protein and Mediates Cell Death in Neurodegeneration. The Journal of Neuroscience 32:44, pages 15565-15576.
Crossref
Crossref
Bernhard M. Kohli, Delphine Pflieger, Lukas N. Mueller, Giovanni Carbonetti, Ruedi Aebersold, Roger M. Nitsch & Uwe Konietzko. (2012) Interactome of the Amyloid Precursor Protein APP in Brain Reveals a Protein Network Involved in Synaptic Vesicle Turnover and a Close Association with Synaptotagmin-1. Journal of Proteome Research 11:8, pages 4075-4090.
Crossref
Crossref
Arunabha Chakrabarti & Debashis Mukhopadhyay. (2012) Novel Adaptors of Amyloid Precursor Protein Intracellular Domain and Their Functional Implications. Genomics, Proteomics & Bioinformatics 10:4, pages 208-216.
Crossref
Crossref
Fangfang Zhou, Kai Gong, Bo Song, Tuo Ma, Theo van Laar, Yandao Gong & Long Zhang. (2012) The APP intracellular domain (AICD) inhibits Wnt signalling and promotes neurite outgrowth. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:8, pages 1233-1241.
Crossref
Crossref
A. Vagnoni, M. S. Perkinton, E. H. Gray, P. T. Francis, W. Noble & C. C. J. Miller. (2012) Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates A production. Human Molecular Genetics 21:13, pages 2845-2854.
Crossref
Crossref
Wan Ning Vanessa Chow, Hon Wing Luk, Ho Yin Edwin Chan & Kwok-Fai Lau. (2012) Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65. Biochemical Journal 443:3, pages 681-689.
Crossref
Crossref
Anja-Silke Beyer, Bjoern von Einem, Daniel Schwanzar, Ilona E. Keller, Anke Hellrung, Dietmar R. Thal, Martin Ingelsson, Alexandra Makarova, Meihua Deng, Ekta S. Chhabra, Christian Pröpper, Tobias M. Böckers, Bradley T. Hyman & Christine A.F. von Arnim. (2012) Engulfment adapter PTB domain containing 1 interacts with and affects processing of the amyloid-β precursor protein. Neurobiology of Aging 33:4, pages 732-743.
Crossref
Crossref
Collin Y. Ewald & Chris Li. (2011) Caenorhabditis elegans as a model organism to study APP function. Experimental Brain Research 217:3-4, pages 397-411.
Crossref
Crossref
Timo Wagner & Claus U. Pietrzik. (2011) The role of lipoprotein receptors on the physiological function of APP. Experimental Brain Research 217:3-4, pages 377-387.
Crossref
Crossref
Maria F. MatosYibin Xu, Irina Dulubova, Zbyszek Otwinowski, John M. Richardson, Diana R. Tomchick, Josep Rizo & Angela Ho. (2012) Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing. Proceedings of the National Academy of Sciences 109:10, pages 3802-3807.
Crossref
Crossref
Caroline Beckett, Natalia N. Nalivaeva, Nikolai D. Belyaev & Anthony J. Turner. (2012) Nuclear signalling by membrane protein intracellular domains: The AICD enigma. Cellular Signalling 24:2, pages 402-409.
Crossref
Crossref
Daniel A. Bórquez & Christian González-Billault. (2012) The Amyloid Precursor Protein Intracellular Domain-Fe65 Multiprotein Complexes: A Challenge to the Amyloid Hypothesis for Alzheimer's Disease?. International Journal of Alzheimer's Disease 2012, pages 1-10.
Crossref
Crossref
Mario Nizzari, Stefano Thellung, Alessandro Corsaro, Valentina Villa, Aldo Pagano, Carola Porcile, Claudio Russo & Tullio Florio. (2012) Neurodegeneration in Alzheimer Disease: Role of Amyloid Precursor Protein and Presenilin 1 Intracellular Signaling. Journal of Toxicology 2012, pages 1-13.
Crossref
Crossref
Han Zhang, Qilin Ma, Yun‐wu Zhang & Huaxi Xu. (2011) Proteolytic processing of Alzheimer’s β‐amyloid precursor protein. Journal of Neurochemistry 120:s1, pages 9-21.
Crossref
Crossref
Raphaëlle Pardossi‐Piquard & Frédéric Checler. (2011) The physiology of the β‐amyloid precursor protein intracellular domain AICD. Journal of Neurochemistry 120:s1, pages 109-124.
Crossref
Crossref
Su Ling Leong, Kevin J. Barnham, Gerd Multhaup & Roberto Cappai. 2011. Encyclopedia of Inorganic and Bioinorganic Chemistry. Encyclopedia of Inorganic and Bioinorganic Chemistry.
Sara Catarina Domingues, Ana Gabriela Henriques, Margarida Fardilha, Edgar F. da Cruz e Silva & Odete A.B. da Cruz e Silva. (2011) Identification and characterization of a neuronal enriched novel transcript encoding the previously described p60Fe65 isoform. Journal of Neurochemistry 119:5, pages 1086-1098.
Crossref
Crossref
S. Sakura Minami, Hyang-Sook Hoe & G. William Rebeck. (2011) Fyn kinase regulates the association between amyloid precursor protein and Dab1 by promoting their localization to detergent-resistant membranes. Journal of Neurochemistry 118:5, pages 879-890.
Crossref
Crossref
Fangfang Zhou, Kai Gong, Theo van Laar, Yandao Gong & Long Zhang. (2011) Wnt/β-catenin signal pathway stabilizes APP intracellular domain (AICD) and promotes its transcriptional activity. Biochemical and Biophysical Research Communications 412:1, pages 68-73.
Crossref
Crossref
Richard J. O'Brien & Philip C. Wong. (2011) Amyloid Precursor Protein Processing and Alzheimer's Disease. Annual Review of Neuroscience 34:1, pages 185-204.
Crossref
Crossref
Melinda M. Mulvihill, Miklos Guttman & Elizabeth A. Komives. (2011) Protein Interactions among Fe65, the Low-Density Lipoprotein Receptor-Related Protein, and the Amyloid Precursor Protein. Biochemistry 50:28, pages 6208-6216.
Crossref
Crossref
Candy Yan Hao, Michael S. PerkintonWilliam Wai-Lun Chan, Ho Yin Edwin Chan, Christopher C. J. MillerKwok-Fai Lau. (2011) GULP1 is a novel APP-interacting protein that alters APP processing. Biochemical Journal 436:3, pages 631-639.
Crossref
Crossref
Ling-Ling Yao, Xue-Yuan Liu, Ji-Yang Jin, Bei-Bei Tao, Yu-Juan Chen, Yong-Chun Yu, Wei-Hong Bian, Jing Yu, Jing Huang & Yong-Gang Wang. (2010) Expression and ultrastructural localization of Mint2 in the spinal cord of rats. Molecular Biology Reports 38:1, pages 667-673.
Crossref
Crossref
Gennaro Schettini, Stefano Govoni, Marco Racchi & Guido Rodriguez. (2010) Phosphorylation of APP-CTF-AICD domains and interaction with adaptor proteins: signal transduction and/or transcriptional role - relevance for Alzheimer pathology. Journal of Neurochemistry 115:6, pages 1299-1308.
Crossref
Crossref
Susan A. Austin & Colin K. Combs. (2010) Amyloid precursor protein mediates monocyte adhesion in AD tissue and apoE−/− mice. Neurobiology of Aging 31:11, pages 1854-1866.
Crossref
Crossref
Oh Yeun Kwon, Kyounghee Hwang, Jeom-A Kim, Kwangmyung Kim, Ick Chan Kwon, Hyun Kyu Song & Hyesung Jeon. (2010) Dab1 binds to Fe65 and diminishes the effect of Fe65 or LRP1 on APP processing. Journal of Cellular Biochemistry 111:2, pages 508-519.
Crossref
Crossref
Kwok-Fai Lau, Michael S. Perkinton, Lilia Rodriguez, Declan M. McLoughlin & Christopher C.J. Miller. (2010) An X11α/FSBP complex represses transcription of the GSK3β gene promoter. NeuroReport 21:11, pages 761-766.
Crossref
Crossref
Xin Tong, Diana Zitserman, Ilya Serebriiskii, Mark Andrake, Roland Dunbrack & Fabrice Roegiers. (2010) Numb Independently Antagonizes Sanpodo Membrane Targeting and Notch Signaling in Drosophila Sensory Organ Precursor Cells. Molecular Biology of the Cell 21:5, pages 802-810.
Crossref
Crossref
S. Sakura Minami, You Me Sung, Sonya B. Dumanis, Seong Hwan Chi, Mark P. Burns, Eun-Jung Ann, Toshiharu Suzuki, R. Scott Turner, Hee-Sae Park, Daniel T. S. Pak, G. William Rebeck & Hyang-Sook Hoe. (2009) The cytoplasmic adaptor protein X11α and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement. The FASEB Journal 24:1, pages 58-69.
Crossref
Crossref
Hidekuni Yamakawa, Sosuke Yagishita, Eugene Futai & Shoichi Ishiura. (2010) β-Secretase Inhibitor Potency Is Decreased by Aberrant β-Cleavage Location of the “Swedish Mutant” Amyloid Precursor Protein. Journal of Biological Chemistry 285:3, pages 1634-1642.
Crossref
Crossref
Katsuhisa Kawai, Shin-ya Kitamura, Koji Maehira, Jun-ichi Seike & Hitoshi Yagisawa. (2010) START-GAP1/DLC1 is localized in focal adhesions through interaction with the PTB domain of tensin2. Advances in Enzyme Regulation 50:1, pages 202-215.
Crossref
Crossref
Amanda Caster & Richard A. Kahn. 2010. Handbook of Cell Signaling. Handbook of Cell Signaling
1803
1812
.
Robert Tamayev, Dawang Zhou & Luciano D'Adamio. (2009) The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains. Molecular Neurodegeneration 4:1.
Crossref
Crossref
Susan A. Austin, Mary A. Sens & Colin K. Combs. (2009) Amyloid Precursor Protein Mediates a Tyrosine Kinase-Dependent Activation Response in Endothelial Cells. The Journal of Neuroscience 29:46, pages 14451-14462.
Crossref
Crossref
Virgil MuresanZoia Muresan. (2009) Is abnormal axonal transport a cause, a contributing factor or a consequence of the neuronal pathology in Alzheimer’s disease?. Future Neurology 4:6, pages 761-773.
Crossref
Crossref
K. Laky, W. Annaert & B. J. Fowlkes. (2009) Amyloid precursor family proteins are expressed by thymic and lymph node stromal cells but are not required for lymphocyte development. International Immunology 21:10, pages 1163-1174.
Crossref
Crossref
Yan Wang, Ming Zhang, Changjong Moon, Qubai Hu, Baiping Wang, George Martin, Zhongsheng Sun & Hongbing Wang. (2009) The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation. Learning & Memory 16:9, pages 537-544.
Crossref
Crossref
Jun-Feng Hou, Jia Cui, Long-Chuan Yu & Yan Zhang. (2009) Intracellular amyloid induces impairments on electrophysiological properties of cultured human neurons. Neuroscience Letters 462:3, pages 294-299.
Crossref
Crossref
Kristin T. Jacobsen & Kerstin Iverfeldt. (2009) Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors. Cellular and Molecular Life Sciences 66:14, pages 2299-2318.
Crossref
Crossref
Gideon M. Shaked, Stephanie Chauv, Kiren Ubhi, Lawrence A. Hansen & Eliezer Masliah. (2009) Interactions between the amyloid precursor protein C-terminal domain and G proteins mediate calcium dysregulation and amyloid β toxicity in Alzheimer’s disease. FEBS Journal 276:10, pages 2736-2751.
Crossref
Crossref
Yong Zhang, Yong-Gang Wang, Qi Zhang, Xiu-Jie Liu, Xuan Liu, Li Jiao, Wei Zhu, Zhao-Huan Zhang, Xiao-Lin Zhao & Cheng He. (2009) Interaction of Mint2 with TrkA Is Involved in Regulation of Nerve Growth Factor-induced Neurite Outgrowth. Journal of Biological Chemistry 284:18, pages 12469-12479.
Crossref
Crossref
Yun Liu, Yun-wu Zhang, Xin Wang, Han Zhang, Xiaoqing You, Francesca-Fang Liao & Huaxi Xu. (2009) Intracellular Trafficking of Presenilin 1 Is Regulated by β-Amyloid Precursor Protein and Phospholipase D1. Journal of Biological Chemistry 284:18, pages 12145-12152.
Crossref
Crossref
Maria-Paz Marzolo & Guojun Bu. (2009) Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease. Seminars in Cell & Developmental Biology 20:2, pages 191-200.
Crossref
Crossref
Maria Stante, Giuseppina Minopoli, Fabiana Passaro, Maddalena RaiaLuigi Del Vecchio & Tommaso Russo. (2009) Fe65 is required for Tip60-directed histone H4 acetylation at DNA strand breaks. Proceedings of the National Academy of Sciences 106:13, pages 5093-5098.
Crossref
Crossref
Virgil Muresan, Nicholas H. Varvel, Bruce T. Lamb & Zoia Muresan. (2009) The Cleavage Products of Amyloid-β Precursor Protein Are Sorted to Distinct Carrier Vesicles That Are Independently Transported within Neurites. The Journal of Neuroscience 29:11, pages 3565-3578.
Crossref
Crossref
Eun Jeoung LeeSunghee HyunJaesun ChunSung Hwa ShinSang Sun Kang. (2009) Ubiquitylation of Fe65 adaptor protein by neuronal precursor cell expressed developmentally down regulated 4-2 (Nedd4-2) via the WW domain interaction with Fe65. Experimental and Molecular Medicine 41:8, pages 555.
Crossref
Crossref
Ken-ichi Takayama, Shuichi Tsutsumi, Takashi Suzuki, Kuniko Horie-Inoue, Kazuhiro Ikeda, Kiyofumi Kaneshiro, Tetsuya Fujimura, Jinpei Kumagai, Tomohiko Urano, Yoshiyuki Sakaki, Katsuhiko Shirahige, Hironobu Sasano, Satoru Takahashi, Tadaichi Kitamura, Yasuyoshi Ouchi, Hiroyuki Aburatani & Satoshi Inoue. (2009) Amyloid Precursor Protein Is a Primary Androgen Target Gene That Promotes Prostate Cancer Growth. Cancer Research 69:1, pages 137-142.
Crossref
Crossref
Angelika Barnekow, Anika Thyrock & Daniel Kessler. 2009.
235
274
.
Nava SegevNaveen Nagarajan, Kenneth L. Custer & Sandra Bajjalieh. 2009. Trafficking Inside Cells. Trafficking Inside Cells
84
102
.
Angela Ho, Xinran Liu & Thomas C. Südhof. (2008) Deletion of Mint Proteins Decreases Amyloid Production in Transgenic Mouse Models of Alzheimer's Disease. The Journal of Neuroscience 28:53, pages 14392-14400.
Crossref
Crossref
Kwok-Fai Lau, Wing-Man Chan, Michael S. Perkinton, Elizabeth L. Tudor, Raymond C.C. Chang, H.-Y. Edwin Chan, Declan M. McLoughlin & Christopher C.J. Miller. (2008) Dexras1 Interacts with FE65 to Regulate FE65-Amyloid Precursor Protein-dependent Transcription. Journal of Biological Chemistry 283:50, pages 34728-34737.
Crossref
Crossref
Francesco Napolitano, Fulvio D’Angelo, Marida Bimonte, Valeria Perrina, Chiara D’Ambrosio, Andrea Scaloni, Tommaso Russo & Nicola Zambrano. (2008) A Differential Proteomic Approach Reveals an Evolutionary Conserved Regulation of Nme Proteins by Fe65 in C. elegans and Mouse. Neurochemical Research 33:12, pages 2547-2555.
Crossref
Crossref
Hua Li, Seizo Koshiba, Fumiaki Hayashi, Naoya Tochio, Tadashi Tomizawa, Takuma Kasai, Takashi Yabuki, Yoko Motoda, Takushi Harada, Satoru Watanabe, Makoto Inoue, Yoshihide Hayashizaki, Akiko Tanaka, Takanori Kigawa & Shigeyuki Yokoyama. (2008) Structure of the C-terminal Phosphotyrosine Interaction Domain of Fe65L1 Complexed with the Cytoplasmic Tail of Amyloid Precursor Protein Reveals a Novel Peptide Binding Mode. Journal of Biological Chemistry 283:40, pages 27165-27178.
Crossref
Crossref
Hyang-Sook Hoe & George William Rebeck. (2008) Functional interactions of APP with the apoE receptor family. Journal of Neurochemistry 106:6, pages 2263-2271.
Crossref
Crossref
Jens Radzimanowski, Stéphanie Ravaud, Sabine Schlesinger, Joachim Koch, Konrad Beyreuther, Irmgard Sinning & Klemens Wild. (2008) Crystal Structure of the Human Fe65-PTB1 Domain. Journal of Biological Chemistry 283:34, pages 23113-23120.
Crossref
Crossref
Thorsten Müller, Helmut E. Meyer, Rupert Egensperger & Katrin Marcus. (2008) The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics—Relevance for Alzheimer's disease. Progress in Neurobiology 85:4, pages 393-406.
Crossref
Crossref
Tadashi Nakaya, Tomoko Kawai & Toshiharu Suzuki. (2008) Regulation of FE65 Nuclear Translocation and Function by Amyloid β-Protein Precursor in Osmotically Stressed Cells. Journal of Biological Chemistry 283:27, pages 19119-19131.
Crossref
Crossref
Garrett G. Gross, R. M. Renny Feldman, Atish Ganguly, Jinhui Wang, Hong Yu & Ming Guo. (2008) Role of X11 and ubiquilin as In Vivo Regulators of the Amyloid Precursor Protein in Drosophila. PLoS ONE 3:6, pages e2495.
Crossref
Crossref
Jiyeon Lee, Claudio Retamal, Loreto Cuitiño, Amy Caruano-Yzermans, Jung-Eun Shin, Peter van Kerkhof, Maria-Paz Marzolo & Guojun Bu. (2008) Adaptor Protein Sorting Nexin 17 Regulates Amyloid Precursor Protein Trafficking and Processing in the Early Endosomes. Journal of Biological Chemistry 283:17, pages 11501-11508.
Crossref
Crossref
Tony Pawson, Gerald D. Gish & Piers Nash. 2008. Protein Science Encyclopedia. Protein Science Encyclopedia.
Ben Margolis & Linton M. Traub. 2008. Protein Science Encyclopedia. Protein Science Encyclopedia.
Declan M. McLoughlin & Christopher C.J. Miller. (2008) The FE65 proteins and Alzheimer's disease. Journal of Neuroscience Research 86:4, pages 744-754.
Crossref
Crossref
Peter Wostyn, Kurt Audenaert & Peter Paul De Deyn. (2008) Alzheimer's disease-related changes in diseases characterized by elevation of intracranial or intraocular pressure. Clinical Neurology and Neurosurgery 110:2, pages 101-109.
Crossref
Crossref
Hyang-Sook Hoe & G. William Rebeck. (2008) Regulated Proteolysis of APP and ApoE Receptors. Molecular Neurobiology 37:1, pages 64-72.
Crossref
Crossref
Punya Shrivastava-Ranjan, Victor Faundez, Guofu Fang, Howard Rees, James J. Lah, Allan I. Levey & Richard A. Kahn. (2008)
Mint3/X11γ Is an ADP-Ribosylation Factor-dependent Adaptor that Regulates the Traffic of the Alzheimer's Precursor Protein from the
Trans
-Golgi Network
. Molecular Biology of the Cell 19:1, pages 51-64.
Crossref
Crossref
Yu Bai, Kelly Markham, Fusheng Chen, Rasanjala Weerasekera, Joel Watts, Patrick Horne, Yosuke Wakutani, Rick Bagshaw, Paul M. Mathews, Paul E. Fraser, David Westaway, Peter St. George-Hyslop & Gerold Schmitt-Ulms. (2008) The in Vivo Brain Interactome of the Amyloid Precursor Protein. Molecular & Cellular Proteomics 7:1, pages 15-34.
Crossref
Crossref
Albéna Pramatarova, Kelian Chen & Brian W. Howell. (2008) A genetic interaction between the APP and Dab1 genes influences brain development. Molecular and Cellular Neuroscience 37:1, pages 178-186.
Crossref
Crossref
Jesse C. Wiley, Elise A. Smith, Mark P. Hudson, Warren C. Ladiges & Mark Bothwell. (2007) Fe65 Stimulates Proteolytic Liberation of the β-Amyloid Precursor Protein Intracellular Domain. Journal of Biological Chemistry 282:46, pages 33313-33325.
Crossref
Crossref
Chitra Venugopal, Miguel A. Pappolla & Kumar Sambamurti. (2007) Insulysin Cleaves the APP Cytoplasmic Fragment at Multiple Sites. Neurochemical Research 32:12, pages 2225-2234.
Crossref
Crossref
Qiang Liu, Celina V. Zerbinatti, Juan Zhang, Hyang-Sook Hoe, Baiping Wang, Sarah L. Cole, Joachim Herz, Louis Muglia & Guojun Bu. (2007) Amyloid Precursor Protein Regulates Brain Apolipoprotein E and Cholesterol Metabolism through Lipoprotein Receptor LRP1. Neuron 56:1, pages 66-78.
Crossref
Crossref
Su Ling Leong, Kevin J. Barnham, Gerd Multhaup & Roberto Cappai. 2006. Handbook of Metalloproteins. Handbook of Metalloproteins.
Yvonne S. Eisele, Matthias Baumann, Bert Klebl, Christina Nordhammer, Mathias Jucker & Ellen Kilger. (2007) Gleevec Increases Levels of the Amyloid Precursor Protein Intracellular Domain and of the Amyloid-β–degrading Enzyme Neprilysin. Molecular Biology of the Cell 18:9, pages 3591-3600.
Crossref
Crossref
Muthuraman Meiyappan, Gabriel Birrane & John A.A. Ladias. (2007) Structural Basis for Polyproline Recognition by the FE65 WW Domain. Journal of Molecular Biology 372:4, pages 970-980.
Crossref
Crossref
Sandra Huysseune, Pascal Kienlen-Campard & Jean-Noël Octave. (2007) Fe65 does not stabilize AICD during activation of transcription in a luciferase assay. Biochemical and Biophysical Research Communications 361:2, pages 317-322.
Crossref
Crossref
Mario Nizzari, Valentina Venezia, Emanuela Repetto, Valentina Caorsi, Raffaella Magrassi, Maria Cristina Gagliani, Pia Carlo, Tullio Florio, Gennaro Schettini, Carlo Tacchetti, Tommaso Russo, Alberto Diaspro & Claudio Russo. (2007) Amyloid Precursor Protein and Presenilin1 Interact with the Adaptor GRB2 and Modulate ERK 1,2 Signaling. Journal of Biological Chemistry 282:18, pages 13833-13844.
Crossref
Crossref
Matthias Gralle & Sérgio T. Ferreira. (2007) Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts. Progress in Neurobiology 82:1, pages 11-32.
Crossref
Crossref
Annat F. Ikin, Shasta L. Sabo, Lorene M. Lanier & Joseph D. Buxbaum. (2007) A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching. Molecular and Cellular Neuroscience 35:1, pages 57-63.
Crossref
Crossref
Rachael L. Neve & Donna L. McPhie. (2007) Dysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1772:4, pages 430-437.
Crossref
Crossref
Loukia Parisiadou & Spiros Efthimiopoulos. (2007) Expression of mDab1 promotes the stability and processing of amyloid precursor protein and this effect is counteracted by X11α. Neurobiology of Aging 28:3, pages 377-388.
Crossref
Crossref
Angela Ho, Wade Morishita, Deniz Atasoy, Xinran Liu, Katsuhiko Tabuchi, Robert E. Hammer, Robert C. Malenka & Thomas C. Südhof. (2006) Genetic Analysis of Mint/X11 Proteins: Essential Presynaptic Functions of a Neuronal Adaptor Protein Family. The Journal of Neuroscience 26:50, pages 13089-13101.
Crossref
Crossref
V. VENEZIA, M. NIZZARI, E. REPETTO, E. VIOLANI, A. CORSARO, S. THELLUNG, V. VILLA, P. CARLO, G. SCHETTINI, T. FLORIO & C. RUSSO. (2006) Amyloid Precursor Protein Modulates ERK-1 and -2 Signaling. Annals of the New York Academy of Sciences 1090:1, pages 455-465.
Crossref
Crossref
Toshinori Ozaki, Yuanyuan Li, Hironobu Kikuchi, Taisuke Tomita, Takeshi Iwatsubo & Akira Nakagawara. (2006) The intracellular domain of the amyloid precursor protein (AICD) enhances the p53-mediated apoptosis. Biochemical and Biophysical Research Communications 351:1, pages 57-63.
Crossref
Crossref
X. Meckler, E. Bertandeau, M. A. McNiven, B. Allinquant & A. Hémar. (2006) The cytosolic domain of APP induces the relocalization of dynamin 3 in hippocampal neurons. European Journal of Neuroscience 24:9, pages 2439-2443.
Crossref
Crossref
Scott A. Small & Sam Gandy. (2006) Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis. Neuron 52:1, pages 15-31.
Crossref
Crossref
Peggy C. Stolt & Hans H. Bock. (2006) Modulation of lipoprotein receptor functions by intracellular adaptor proteins. Cellular Signalling 18:10, pages 1560-1571.
Crossref
Crossref
Bernd Weber, Christian Schaper, Jens Scholz, Berthold Bein, Cornelia Rodde & Peter H. Tonner. (2006) Interaction of the amyloid precursor like protein 1 with the α2A-adrenergic receptor increases agonist-mediated inhibition of adenylate cyclase. Cellular Signalling 18:10, pages 1748-1757.
Crossref
Crossref
Boris Rogelj, Jacqueline C. Mitchell, Christopher C.J. Miller & Declan M. McLoughlin. (2006) The X11/Mint family of adaptor proteins. Brain Research Reviews 52:2, pages 305-315.
Crossref
Crossref
Hyang-Sook Hoe, Laura Ann Magill, Suzanne Guenette, Zhanyan Fu, Stefano Vicini & G. William Rebeck. (2006) FE65 Interaction with the ApoE Receptor ApoEr2. Journal of Biological Chemistry 281:34, pages 24521-24530.
Crossref
Crossref
Rachael L. Neve & Donna L. McPhie. (2006) The cell cycle as a therapeutic target for Alzheimer's disease. Pharmacology & Therapeutics 111:1, pages 99-113.
Crossref
Crossref
Tadashi Nakaya & Toshiharu Suzuki. (2006) Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD. Genes to Cells 11:6, pages 633-645.
Crossref
Crossref
Christopher C.J. Miller, Declan M. McLoughlin, Kwok-Fai Lau, Maria E. Tennant & Boris Rogelj. (2006) The X11 proteins, Aβ production and Alzheimer's disease. Trends in Neurosciences 29:5, pages 280-285.
Crossref
Crossref
C. M. Sondag & C. K. Combs. (2006) Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells. Journal of Neurochemistry 97:2, pages 449-461.
Crossref
Crossref
Zhongcong Xie & Rudolph E. Tanzi. (2006) Alzheimer's disease and post-operative cognitive dysfunction. Experimental Gerontology 41:4, pages 346-359.
Crossref
Crossref
Stephanie Neumann, Susanne Schöbel, Sebastian Jäger, Anna Trautwein, Christian Haass, Claus U. Pietrzik & Stefan F. Lichtenthaler. (2006) Amyloid Precursor-like Protein 1 Influences Endocytosis and Proteolytic Processing of the Amyloid Precursor Protein. Journal of Biological Chemistry 281:11, pages 7583-7594.
Crossref
Crossref
Ting-Yu Chen, Pei-Hsueh Liu, Chi-Tun Ruan, Ling Chiu & Fan-Lu Kung. (2006) The intracellular domain of amyloid precursor protein interacts with flotillin-1, a lipid raft protein. Biochemical and Biophysical Research Communications 342:1, pages 266-272.
Crossref
Crossref
Katleen Dillen & Wim Annaert. 2006.
215
300
.
Zoia Muresan & Virgil Muresan. (2005) Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH2-terminal kinase–interacting protein-1. Journal of Cell Biology 171:4, pages 615-625.
Crossref
Crossref
Kathleen A. Ryan & Sanjay W. Pimplikar. (2005) Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain. Journal of Cell Biology 171:2, pages 327-335.
Crossref
Crossref
Michael Knop, K. Juha Miller, Massimiliano Mazza, DeJiang Feng, Marion Weber, Sirkka Keränen & Jussi Jäntti. (2005) Molecular Interactions Position Mso1p, a Novel PTB Domain Homologue, in the Interface of the Exocyst Complex and the Exocytic SNARE Machinery in Yeast. Molecular Biology of the Cell 16:10, pages 4543-4556.
Crossref
Crossref
Maarten Leyssen, Derya Ayaz, Sébastien S Hébert, Simon Reeve, Bart De Strooper & Bassem A Hassan. (2005) Amyloid precursor protein promotes post-developmental neurite arborization in the Drosophila brain. The EMBO Journal 24:16, pages 2944-2955.
Crossref
Crossref
Jia-Fu Long, Wei Feng, Rui Wang, Ling-Nga Chan, Fanny C F Ip, Jun Xia, Nancy Y Ip & Mingjie Zhang. (2005) Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem. Nature Structural & Molecular Biology 12:8, pages 722-728.
Crossref
Crossref
Kevin M. Patrie. (2005) Identification and characterization of a novel tight junction-associated family of proteins that interacts with a WW domain of MAGI-1. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1745:1, pages 131-144.
Crossref
Crossref
Iskender Teber, Fumiko Nagano, Joachim Kremerskothen, Konstantinos Bilbilis, Bruno Goud & Angelika Barnekow. (2005) Rab6 interacts with the mint3 adaptor protein. Biological Chemistry 386:7, pages 671-677.
Crossref
Crossref
Alberto Lleó, Elaine Waldron, Christine A.F. von Arnim, Lauren Herl, Michele M. Tangredi, Ithan D. Peltan, Dudley K. Strickland, Edward H. Koo, Bradley T. Hyman, Claus U. Pietrzik & Oksana Berezovska. (2005) Low Density Lipoprotein Receptor-related Protein (LRP) Interacts with Presenilin 1 and Is a Competitive Substrate of the Amyloid Precursor Protein (APP) for γ-Secretase. Journal of Biological Chemistry 280:29, pages 27303-27309.
Crossref
Crossref
James Ashley, Mary Packard, Bulent Ataman & Vivian Budnik. (2005) Fasciclin II Signals New Synapse Formation through Amyloid Precursor Protein and the Scaffolding Protein dX11/Mint. The Journal of Neuroscience 25:25, pages 5943-5955.
Crossref
Crossref
Il-Sang Yoon, Claus U. Pietrzik, David E. Kang & Edward H. Koo. (2005) Sequences from the Low Density Lipoprotein Receptor-related Protein (LRP) Cytoplasmic Domain Enhance Amyloid β Protein Production via the β-Secretase Pathway without Altering Amyloid Precursor Protein/LRP Nuclear Signaling. Journal of Biological Chemistry 280:20, pages 20140-20147.
Crossref
Crossref
Megan L. Kerr & David H. Small. (2005) Cytoplasmic domain of the ?-amyloid protein precursor of Alzheimer's disease: Function, regulation of proteolysis, and implications for drug development. Journal of Neuroscience Research 80:2, pages 151-159.
Crossref
Crossref
Zoia Muresan & Virgil Muresan. (2005)
c-Jun NH
2
-Terminal Kinase-Interacting Protein-3 Facilitates Phosphorylation and Controls Localization of Amyloid-β Precursor Protein
. The Journal of Neuroscience 25:15, pages 3741-3751.
Crossref
Crossref
Dominique Santiard-Baron, Dominique Langui, Maryse Delehedde, Benoît Delatour, Brigitte Schombert, Nathalie Touchet, Günter Tremp, Marie-Françoise Paul, Véronique Blanchard, Nicolas Sergeant, André Delacourte, Charles Duyckaerts, Laurent Pradier & Luc Mercken. (2005) Expression of human FE65 in amyloid precursor protein transgenic mice is associated with a reduction in β-amyloid load. Journal of Neurochemistry 93:2, pages 330-338.
Crossref
Crossref
Zhongcong Xie, Donna M. Romano & Rudolph E. Tanzi. (2005) RNA Interference-mediated Silencing of X11α and X11β Attenuates Amyloid β-Protein Levels via Differential Effects on β-Amyloid Precursor Protein Processing. Journal of Biological Chemistry 280:15, pages 15413-15421.
Crossref
Crossref
Claudio Russo, Valentina Venezia, Emanuela Repetto, Mario Nizzari, Elisabetta Violani, Pia Carlo & Gennaro Schettini. (2005) The amyloid precursor protein and its network of interacting proteins: physiological and pathological implications. Brain Research Reviews 48:2, pages 257-264.
Crossref
Crossref
Doreen R. Glodowski, Tricia Wright, Keri Martinowich, Howard Chia-Hao Chang, Douglas Beach & Christopher Rongo. (2005) Distinct LIN-10 Domains Are Required for Its Neuronal Function, Its Epithelial Function, and Its Synaptic Localization. Molecular Biology of the Cell 16:3, pages 1417-1426.
Crossref
Crossref
Christian Hölscher. (2005) Development of Beta-Amyloid-induced Neurodegeneration in Alzheimer's Disease and Novel Neuroprotective Strategies. Reviews in the Neurosciences 16:3.
Crossref
Crossref
Mark T. Uhlik, Brenda Temple, Sompop Bencharit, Adam J. Kimple, David P. Siderovski & Gary L. Johnson. (2005) Structural and Evolutionary Division of Phosphotyrosine Binding (PTB) Domains. Journal of Molecular Biology 345:1, pages 1-20.
Crossref
Crossref
Displaying 200 of 375 citing articles. Use the download link below to view the full list of citing articles.
Download full citations list