20
Views
153
CrossRef citations to date
0
Altmetric
Research Article

Antagonism between Nur77 and Glucocorticoid Receptor for Control of Transcription

, , , , , & show all
Pages 5952-5959 | Received 22 May 1997, Accepted 11 Jul 1997, Published online: 29 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (10)

Julia K Gjerstad, Stafford L Lightman & Francesca Spiga. (2018) Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility. Stress 21:5, pages 403-416.
Read now
Sally KY To, Jin-Zhang Zeng & Alice ST Wong. (2012) Nur77: a potential therapeutic target in cancer. Expert Opinion on Therapeutic Targets 16:6, pages 573-585.
Read now
Sung-Soo Park & Eungseok Kim. (2012) Nur77 inhibits TR4-induced PEPCK expression in 3T3-L1 adipocytes. Animal Cells and Systems 16:2, pages 87-94.
Read now
Heike Schäcke, Markus Berger, Thomas G Hansson, Darren McKerrecher & Hartmut Rehwinkel. (2008) Dissociated non-steroidal glucocorticoid receptor modulators: an update on new compounds. Expert Opinion on Therapeutic Patents 18:3, pages 339-352.
Read now
Flávio S. J. de Souza, Andrea M. Santangelo, Viviana Bumaschny, María Elena Avale, James L. Smart, Malcolm J. Low & Marcelo Rubinstein. (2005) Identification of Neuronal Enhancers of the Proopiomelanocortin Gene by Transgenic Mouse Analysis and Phylogenetic Footprinting. Molecular and Cellular Biology 25:8, pages 3076-3086.
Read now
Siva Kumar Kolluri, Nathalie Bruey-Sedano, Xihua Cao, Bingzhen Lin, Feng Lin, Young-Hoon Han, Marcia I. Dawson & Xiao-kun Zhang. (2003) Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells. Molecular and Cellular Biology 23:23, pages 8651-8667.
Read now
Mario Maira, Christine Martens, éric Batsché, Yves Gauthier & Jacques Drouin. (2003) Dimer-Specific Potentiation of NGFI-B (Nur77) Transcriptional Activity by the Protein Kinase A Pathway and AF-1-Dependent Coactivator Recruitment. Molecular and Cellular Biology 23:3, pages 763-776.
Read now
Mario Maira, Christine Martens, Alexandre Philips & Jacques Drouin. (1999) Heterodimerization between Members of the Nur Subfamily of Orphan Nuclear Receptors as a Novel Mechanism for Gene Activation. Molecular and Cellular Biology 19:11, pages 7549-7557.
Read now
Gratien G. Préfontaine, Madeleine E. Lemieux, Ward Giffin, Caroline Schild-Poulter, Louise Pope, Eric LaCasse, Peter Walker & Robert J. G. Haché. (1998) Recruitment of Octamer Transcription Factors to DNA by Glucocorticoid Receptor. Molecular and Cellular Biology 18:6, pages 3416-3430.
Read now
Alexandre Philips, Sylvie Lesage, Rock Gingras, Mario-Hernan Maira, Yves Gauthier, Patrice Hugo & Jacques Drouin. (1997) Novel Dimeric Nur77 Signaling Mechanism in Endocrine and Lymphoid Cells. Molecular and Cellular Biology 17:10, pages 5946-5951.
Read now

Articles from other publishers (143)

Lynnette K Nieman. (2022) Molecular Derangements and the Diagnosis of ACTH-Dependent Cushing’s Syndrome. Endocrine Reviews 43:5, pages 852-877.
Crossref
Daniela Regazzo, Alessandro Mondin, Carla Scaroni, Gianluca Occhi & Mattia Barbot. (2022) The Role of Glucocorticoid Receptor in the Pathophysiology of Pituitary Corticotroph Adenomas. International Journal of Molecular Sciences 23:12, pages 6469.
Crossref
Jacques Drouin & Jonathan Brière. 2022. The Pituitary. The Pituitary 3 26 .
Lindsey S. Gaston & Joseph A. Majzoub. 2022. The Pituitary. The Pituitary 51 89 .
Arno Téblick, Sarah Vander Perre, Lies Pauwels, Sarah Derde, Tim Van Oudenhove, Lies Langouche & Greet Van den Berghe. (2021) The role of pro-opiomelanocortin in the ACTH–cortisol dissociation of sepsis. Critical Care 25:1.
Crossref
Yugong Ho, Peng Hu, Michael T. Peel, Sixing Chen, Pablo G. Camara, Douglas J. Epstein, Hao Wu & Stephen A. Liebhaber. (2020) Single-cell transcriptomic analysis of adult mouse pituitary reveals sexual dimorphism and physiologic demand-induced cellular plasticity. Protein & Cell 11:8, pages 565-583.
Crossref
Dongyun Zhang & Anthony P. Heaney. (2020) Nuclear Receptors as Regulators of Pituitary Corticotroph Pro-Opiomelanocortin Transcription. Cells 9:4, pages 900.
Crossref
Rowan S. Hardy, Karim Raza & Mark S. Cooper. (2020) Therapeutic glucocorticoids: mechanisms of actions in rheumatic diseases. Nature Reviews Rheumatology 16:3, pages 133-144.
Crossref
Denis Ciato & Adriana Albani. (2020) Molecular Mechanisms of Glucocorticoid Resistance in Corticotropinomas: New Developments and Drug Targets. Frontiers in Endocrinology 11.
Crossref
Paul R. Mittelstadt, Matthew D. Taves & Jonathan D. Ashwell. (2019) Glucocorticoids Oppose Thymocyte Negative Selection by Inhibiting Helios and Nur77. The Journal of Immunology 203:8, pages 2163-2170.
Crossref
Swati Srivastava, Nishanth Belugali Nataraj, Arunachalam Sekar, Soma Ghosh, Chamutal Bornstein, Diana Drago-Garcia, Lee Roth, Donatella Romaniello, Ilaria Marrocco, Eyal David, Yuval Gilad, Mattia Lauriola, Ron Rotkopf, Adi Kimchi, Yuya Haga, Yasuo Tsutsumi, Olivier Mirabeau, Didier Surdez, Andrei Zinovyev, Olivier Delattre, Heinrich Kovar, Ido Amit & Yosef Yarden. (2019) ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma. Cell Reports 29:1, pages 104-117.e4.
Crossref
Mirjana Nacka-Aleksić, Ivan Pilipović, Jelena Kotur-Stevuljević, Raisa Petrović, Jelena Sopta & Gordana Leposavić. (2019) Sexual dimorphism in rat thymic involution: a correlation with thymic oxidative status and inflammation. Biogerontology 20:4, pages 545-569.
Crossref
Denis Ciato, Ran Li, Jose Luis Monteserin Garcia, Lilia Papst, Sarah D’Annunzio, Michael Hristov, Maria A. Tichomirowa, Zhanna Belaya, Liudmila Rozhinskaya, Michael Buchfelder, Marily Theodoropoulou, Marcelo Paez-Pereda & Günter Karl Stalla. (2019) Inhibition of Heat Shock Factor 1 Enhances Repressive Molecular Mechanisms on the <b><i>POMC</i></b> Promoter. Neuroendocrinology 109:4, pages 362-373.
Crossref
Erika Harno, Thanuja Gali Ramamoorthy, Anthony P. Coll & Anne White. (2018) POMC: The Physiological Power of Hormone Processing. Physiological Reviews 98:4, pages 2381-2430.
Crossref
Jianhua Chen, Xuemin Jian, Siyu Deng, Zengyi Ma, Xuefei Shou, Yue Shen, Qilin Zhang, Zhijian Song, Zhiqiang Li, Hong Peng, Cheng Peng, Min Chen, Cheng Luo, Dan Zhao, Zhao Ye, Ming Shen, Yichao Zhang, Juan Zhou, Aamir Fahira, Yongfei Wang, Shiqi Li, Zhaoyun Zhang, Hongying Ye, Yiming Li, Jiawei Shen, Hong Chen, Feng Tang, Zhenwei Yao, Zhifeng Shi, Chunjui Chen, Lu Xie, Ye Wang, Chaowei Fu, Ying Mao, Liangfu Zhou, Daming Gao, Hai Yan, Yao Zhao, Chuanxin Huang & Yongyong Shi. (2018) Identification of recurrent USP48 and BRAF mutations in Cushing’s disease. Nature Communications 9:1.
Crossref
Paul R. Mittelstadt, Matthew D. Taves & Jonathan D. Ashwell. (2018) Cutting Edge: De Novo Glucocorticoid Synthesis by Thymic Epithelial Cells Regulates Antigen-Specific Thymocyte Selection. The Journal of Immunology 200:6, pages 1988-1994.
Crossref
Marcelo Rubinstein & Malcolm J. Low. (2017) Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesity. FEBS Letters 591:17, pages 2593-2606.
Crossref
Elisa Bianchi, Samantha Ruberti, Sebastiano Rontauroli, Paola Guglielmelli, Simona Salati, Chiara Rossi, Roberta Zini, Enrico Tagliafico, Alessandro Vannucchi & Rossella Manfredini. (2017) Role of miR-34a-5p in Hematopoietic Progenitor Cells Proliferation and Fate Decision: Novel Insights into the Pathogenesis of Primary Myelofibrosis. International Journal of Molecular Sciences 18:1, pages 145.
Crossref
Carmen L. Soto-Rivera & Joseph A. Majzoub. 2017. The Pituitary. The Pituitary 47 83 .
Jacques Drouin. 2017. The Pituitary. The Pituitary 3 22 .
María Emilia Solano, Megan C. Holmes, Paul R. Mittelstadt, Karen E. Chapman & Eva Tolosa. (2016) Antenatal endogenous and exogenous glucocorticoids and their impact on immune ontogeny and long-term immunity. Seminars in Immunopathology 38:6, pages 739-763.
Crossref
Ioanna Petta, Lien Dejager, Marlies Ballegeer, Sam Lievens, Jan Tavernier, Karolien De Bosscher & Claude Libert. (2016) The Interactome of the Glucocorticoid Receptor and Its Influence on the Actions of Glucocorticoids in Combatting Inflammatory and Infectious Diseases. Microbiology and Molecular Biology Reviews 80:2, pages 495-522.
Crossref
Jacques Drouin. (2016) 60 YEARS OF POMC: Transcriptional and epigenetic regulation of POMC gene expression. Journal of Molecular Endocrinology 56:4, pages T99-T112.
Crossref
David W. Ray. 2016. Endocrinology: Adult and Pediatric. Endocrinology: Adult and Pediatric 2628 2639.e4 .
Erika Harno & Anne White. 2016. Endocrinology: Adult and Pediatric. Endocrinology: Adult and Pediatric 129 146.e5 .
Maureen Keller‐Wood. 2011. Comprehensive Physiology. Comprehensive Physiology 1161 1182 .
Mathias Riebold, Christian Kozany, Lee Freiburger, Michael Sattler, Michael Buchfelder, Felix Hausch, Günter K Stalla & Marcelo Paez-Pereda. (2015) A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease. Nature Medicine 21:3, pages 276-280.
Crossref
Sebastiaan H. Meijsing. 2015. Glucocorticoid Signaling. Glucocorticoid Signaling 59 81 .
Kondababu Kurakula, Duco S. Koenis, Claudia M. van Tiel & Carlie J.M. de Vries. (2014) NR4A nuclear receptors are orphans but not lonesome. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:11, pages 2543-2555.
Crossref
Malgorzata Wojcik, Katarzyna Tyrawa, Anna Kalicka-Kasperczyk, Agata Zygmunt-Gorska & Jerzy B. Starzyk. (2014) Atypical Clinical Presentation of Acth-Dependent Cushing's Syndrome in a Patient Treated with Retinoic Acid. Endocrine Practice 20:7, pages e119-e122.
Crossref
Jean-Christophe Helbling, Amandine M. Minni, Véronique Pallet & Marie-Pierre Moisan. (2014) Stress and glucocorticoid regulation of NR4A genes in mice. Journal of Neuroscience Research 92:7, pages 825-834.
Crossref
Felix Grün. 2014. Endocrine Disrupters. Endocrine Disrupters 277 325 .
Shin Y. Park, Jamie J. Walker, Nicholas W. Johnson, Zidong Zhao, Stafford L. Lightman & Francesca Spiga. (2013) Constant light disrupts the circadian rhythm of steroidogenic proteins in the rat adrenal gland. Molecular and Cellular Endocrinology 371:1-2, pages 114-123.
Crossref
Nan Zhang, Jun-kai Lin, Juan Chen, Xiong-fei Liu, Jia-li Liu, Hao-shu Luo, Yue-qin Li & Sheng Cui. (2013) MicroRNA 375 Mediates the Signaling Pathway of Corticotropin-releasing Factor (CRF) Regulating Pro-opiomelanocortin (POMC) Expression by Targeting Mitogen-activated Protein Kinase 8. Journal of Biological Chemistry 288:15, pages 10361-10373.
Crossref
Kalina DuszkaJuliane G. Bogner-Strauss, Hubert HacklDietmar RiederClaudia Neuhold, Andreas Prokesch, Zlatko TrajanoskiAnne-M. Krogsdam. (2013) Nr4a1 Is Required for Fasting-Induced Down-Regulation of Pparγ2 in White Adipose Tissue. Molecular Endocrinology 27:1, pages 135-149.
Crossref
Vivek P. Patel, Donald B. DeFranco & Charleen T. Chu. (2012) Altered transcription factor trafficking in oxidatively-stressed neuronal cells. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1822:11, pages 1773-1782.
Crossref
Yasuyo Nakajima, Masanobu Yamada, Ryo Taguchi, Nobuyuki Shibusawa, Atsushi Ozawa, Takuya Tomaru, Koshi Hashimoto, Tsugumichi Saito, Takafumi Tsuchiya, Shuichi Okada, Tetsurou Satoh & Masatomo Mori. (2012) NR4A1 (Nur77) Mediates Thyrotropin-Releasing Hormone-Induced Stimulation of Transcription of the Thyrotropin β Gene: Analysis of TRH Knockout Mice. PLoS ONE 7:7, pages e40437.
Crossref
David Langlais, Catherine Couture, Aurélio Balsalobre & Jacques Drouin. (2012) The Stat3/GR Interaction Code: Predictive Value of Direct/Indirect DNA Recruitment for Transcription Outcome. Molecular Cell 47:1, pages 38-49.
Crossref
Ana C. Liberman, Damian Refojo, Maria Antunica-Noguerol, Florian Holsboer & Eduardo Arzt. (2012) Underlying mechanisms of cAMP- and glucocorticoid-mediated inhibition of FasL expression in activation-induced cell death. Molecular Immunology 50:4, pages 220-235.
Crossref
Jeffrey B. Eells, Josiah Wilcots, Scott Sisk & Shirley X. Guo-Ross. (2011) NR4A Gene Expression Is Dynamically Regulated in the Ventral Tegmental Area Dopamine Neurons and Is Related to Expression of Dopamine Neurotransmission Genes. Journal of Molecular Neuroscience 46:3, pages 545-553.
Crossref
Carolina Perez-CastroUlrich RennerMariana R. HaedoGunter K. StallaEduardo Arzt. (2012) Cellular and Molecular Specificity of Pituitary Gland Physiology. Physiological Reviews 92:1, pages 1-38.
Crossref
N. Stroth, Y. Liu, G. Aguilera & L. E. Eiden. (2011) Pituitary Adenylate Cyclase-Activating Polypeptide Controls Stimulus-Transcription Coupling in the Hypothalamic-Pituitary-Adrenal Axis to Mediate Sustained Hormone Secretion During Stress. Journal of Neuroendocrinology 23:10, pages 944-955.
Crossref
Leah B. Goldberg, Paven K. Aujla & Lori T. Raetzman. (2011) Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Developmental Biology 358:1, pages 23-32.
Crossref
Danae Campos-Melo, Gabriel Quiroz, Verónica Noches, Katia Gysling, María Inés Forray & María Estela Andrés. (2011) Repeated Immobilization Stress Increases Nur77 Expression in the Bed Nucleus of the Stria Terminalis. Neurotoxicity Research 20:3, pages 289-300.
Crossref
Nicole A. Datson, Niels Speksnijder, Inge E. M. de Jong, Peter J. Steenbergen, Kenneth Vielsted Christensen, Krzysztof Potempa, Jan Torleif Pedersen, Jan Egebjerg, Pekka Kallunki, Erik B. Nielsen, E. Ronald de Kloet & Michael Didriksen. (2011) Hippocampal CA1 region shows differential regulation of gene expression in mice displaying extremes in behavioral sensitization to amphetamine: relevance for psychosis susceptibility?. Psychopharmacology 217:4, pages 525-538.
Crossref
Lionel Budry, Catherine Couture, Aurélio Balsalobre & Jacques Drouin. (2011) The Ets Factor Etv1 Interacts with Tpit Protein for Pituitary Pro-opiomelanocortin (POMC) Gene Transcription. Journal of Biological Chemistry 286:28, pages 25387-25396.
Crossref
F. Pecori Giraldi, F. Cassarino, L. Pagliardini, V. Asnaghi & F. Cavagnini. (2011) The human POMC gene promoter: Where do we stand?. Journal of Endocrinological Investigation 34:6, pages 454-460.
Crossref
Yuji Tani, Toru Sugiyama, Hajime Izumiyama, Takanobu Yoshimoto, Shozo Yamada & Yukio Hirata. (2011) Differential gene expression profiles of POMC-related enzymes, transcription factors and receptors between non-pituitary and pituitary ACTH-secreting tumors. Endocrine Journal 58:4, pages 297-303.
Crossref
Bjørn O. Strøm, Petra Aden, Gro H. Mathisen, Jon Lømo, Svend Davanger & Ragnhild E. Paulsen. (2010) Transfection of chicken cerebellar granule neurons used to study glucocorticoid receptor regulation by nuclear receptor 4A (NR4A). Journal of Neuroscience Methods 193:1, pages 39-46.
Crossref
Audrey Roussel-Gervais, Steve Bilodeau, Sophie Vallette, France Berthelet, André Lacroix, Dominique Figarella-Branger, Thierry Brue & Jacques Drouin. (2010) Cooperation between Cyclin E and p27Kip1 in Pituitary Tumorigenesis. Molecular Endocrinology 24:9, pages 1835-1845.
Crossref
Yue ZhaoDennis Bruemmer. (2010) NR4A Orphan Nuclear Receptors. Arteriosclerosis, Thrombosis, and Vascular Biology 30:8, pages 1535-1541.
Crossref
He Huang, Lei Zhang, Xiaodong Zhang, Xun Ji, Xiao Ding, Xu Shen, Hualiang Jiang & Hong Liu. (2010) Total Synthesis of Cytosporone B. Chinese Journal of Chemistry 28:6, pages 1041-1043.
Crossref
Robert Newton, Richard Leigh & Mark A. Giembycz. (2010) Pharmacological strategies for improving the efficacy and therapeutic ratio of glucocorticoids in inflammatory lung diseases. Pharmacology & Therapeutics 125:2, pages 286-327.
Crossref
David W. Ray. 2010. Endocrinology. Endocrinology 2787 2800 .
Adam Stevens & Anne White. 2010. Endocrinology. Endocrinology 179 198 .
Neil J. Mckenna & David D. Moore. 2010. Endocrinology. Endocrinology 106 117 .
John Newell-Price. 2011. Cushing's Syndrome. Cushing's Syndrome 21 29 .
Young-Jun Seo, Min-Soo Kwon, Seung-Min Choi, Jin-Koo Lee, Soo-Hyun Park, Jun-Sub Jung, Yun-Beom Sim & Hong-Won Suh. (2009) Possible involvement of the hypothalamic pro-opiomelanocortin gene and β-endorphin expression on acute morphine withdrawal development. Brain Research Bulletin 80:6, pages 359-370.
Crossref
Radu C. Oita, Dawn J. Mazzatti, Fei Ling Lim, Jonathan R. Powell & Brian J. Merry. (2009) Whole-genome microarray analysis identifies up-regulation of Nr4a nuclear receptors in muscle and liver from diet-restricted rats. Mechanisms of Ageing and Development 130:4, pages 240-247.
Crossref
G.L. Hager, D.A. Stavreva & T.C. Voss. 2009. Hormones, Brain and Behavior. Hormones, Brain and Behavior 1329 1366 .
David Langlais, Catherine Couture, Aurélio Balsalobre & Jacques Drouin. (2008) Regulatory Network Analyses Reveal Genome-Wide Potentiation of LIF Signaling by Glucocorticoids and Define an Innate Cell Defense Response. PLoS Genetics 4:10, pages e1000224.
Crossref
Wanius Garcia, Ana Carolina M. Figueira, Mario de Oliveira Neto, Carolina A. de Guzzi, Hilde H. Buzzá, Rodrigo V. Portugal, Marcos R. Calgaro & Igor Polikarpov. (2008) Probing conformational changes in orphan nuclear receptor: The NGFI-B intermediate is a partially unfolded dimer. Biophysical Chemistry 137:2-3, pages 81-87.
Crossref
Heike Schäcke, Khusru Asadullah, Markus Berger & Hartmut Rehwinkel. 2008. Nuclear Receptors as Drug Targets. Nuclear Receptors as Drug Targets 305 323 .
Pierre-Luc Lavoie, Lionel Budry, Aurélio Balsalobre & Jacques Drouin. (2008) Developmental Dependence on NurRE and EboxNeuro for Expression of Pituitary Proopiomelanocortin. Molecular Endocrinology 22:7, pages 1647-1657.
Crossref
Y.-J. Seo, M.-S. Kwon, S.-S. Choi, E.-J. Han, J.-S. Jung, H.-W. Choi, S.-H. Park, J.-E. Jang & H.-W. Suh. (2008) Characterization of the hypothalamic proopiomelanocortin gene and β-endorphin expression in the hypothalamic arcuate nucleus of mice elicited by inflammatory pain. Neuroscience 152:4, pages 1054-1066.
Crossref
Rodolphe Carpentier, Paola Sacchetti, Pascaline Ségard, Bart Staels & Philippe Lefebvre. (2007) The glucocorticoid receptor is a co-regulator of the orphan nuclear receptor Nurr1. Journal of Neurochemistry 0:0, pages 071106220615011-???.
Crossref
J Drouin, S Bilodeau & S Vallette. (2007) Of old and new diseases: genetics of pituitary ACTH excess (Cushing) and deficiency. Clinical Genetics 72:3, pages 175-182.
Crossref
Olivier Kassel & Peter Herrlich. (2007) Crosstalk between the glucocorticoid receptor and other transcription factors: Molecular aspects. Molecular and Cellular Endocrinology 275:1-2, pages 13-29.
Crossref
Heike Schäcke, Markus Berger, Hartmut Rehwinkel & Khusru Asadullah. (2007) Selective glucocorticoid receptor agonists (SEGRAs): Novel ligands with an improved therapeutic index. Molecular and Cellular Endocrinology 275:1-2, pages 109-117.
Crossref
Marcos R. Calgaro, Mario de Oliveira Neto, Ana Carolina M. Figueira, Maria A.M. Santos, Rodrigo V. Portugal, Carolina A. Guzzi, Daniel M. Saidemberg, Lucas Bleicher, Javier Vernal, Pablo Fernandez, Hernán Terenzi, Mario Sergio Palma & Igor Polikarpov. (2007) Orphan nuclear receptor NGFI-B forms dimers with nonclassical interface. Protein Science 16:8, pages 1762-1772.
Crossref
Meng Yao & Robert J. Denver. (2007) Regulation of vertebrate corticotropin-releasing factor genes. General and Comparative Endocrinology 153:1-3, pages 200-216.
Crossref
Xiaoyan Zhu, Anatoli S. Gleiberman & Michael G. Rosenfeld. (2007) Molecular Physiology of Pituitary Development: Signaling and Transcriptional Networks. Physiological Reviews 87:3, pages 933-963.
Crossref
Akio Matsushita, Shigekazu Sasaki, Yumiko Kashiwabara, Koji Nagayama, Kenji Ohba, Hiroyuki Iwaki, Hiroko Misawa, Keiko Ishizuka & Hirotoshi Nakamura. (2007) Essential Role of GATA2 in the Negative Regulation of Thyrotropin β Gene by Thyroid Hormone and Its Receptors. Molecular Endocrinology 21:4, pages 865-884.
Crossref
Rutao Cui, Hans R. Widlund, Erez Feige, Jennifer Y. Lin, Dara L. Wilensky, Viven E. Igras, John D'Orazio, Claire Y. Fung, Carl F. Schanbacher, Scott R. Granter & David E. Fisher. (2007) Central Role of p53 in the Suntan Response and Pathologic Hyperpigmentation. Cell 128:5, pages 853-864.
Crossref
Nuno M.M. PiresThijs W.H. PolsMargreet R. de VriesClaudia M. van TielPeter I. BontaMariska VosE. Karin ArkenboutHans PannekoekJ. Wouter JukemaPaul H.A. QuaxCarlie J.M. de Vries. (2007) Activation of Nuclear Receptor Nur77 by 6-Mercaptopurine Protects Against Neointima Formation. Circulation 115:4, pages 493-500.
Crossref
Olivier Latchoumanin, Vanessa Mynard, Jocelyne Devin-Leclerc, Marie-Annick Dugué, Xavier Bertagna & Maria Grazia Catelli. (2007) Reversal of Glucocorticoids-Dependent Proopiomelanocortin Gene Inhibition by Leukemia Inhibitory Factor. Endocrinology 148:1, pages 422-432.
Crossref
Kathleen A Smoak & John A Cidlowski. 2007. The Hypothalamus-Pituitary-Adrenal Axis. The Hypothalamus-Pituitary-Adrenal Axis 33 53 .
K De Bosscher, W Vanden Berghe & G Haegeman. (2006) Cross-talk between nuclear receptors and nuclear factor κB. Oncogene 25:51, pages 6868-6886.
Crossref
Steve Bilodeau, Sophie Vallette-Kasic, Yves Gauthier, Dominique Figarella-Branger, Thierry Brue, France Berthelet, André Lacroix, Dalia Batista, Constantine Stratakis, Jeanette Hanson, Björn Meij & Jacques Drouin. (2006) Role of Brg1 and HDAC2 in GR trans -repression of the pituitary POMC gene and misexpression in Cushing disease . Genes & Development 20:20, pages 2871-2886.
Crossref
Natalia Novac, Daniela Baus, Anja Dostert & Thorsten Heinzel. (2006) Competition between glucocorticoid receptor and NFκB for control of the human FasL promoter. The FASEB Journal 20:8, pages 1074-1081.
Crossref
Jeffrey B. Eells, Jaime A. Misler & Vera M. Nikodem. (2006) Reduced tyrosine hydroxylase and GTP cyclohydrolase mRNA expression, tyrosine hydroxylase activity, and associated neurochemical alterations in Nurr1-null heterozygous mice. Brain Research Bulletin 70:2, pages 186-195.
Crossref
Sung Yul Kim, Kyou Chan Choi, Min Seok Chang, Myoung Hwan Kim, Sa Yong Kim, Young-Soon Na, Jong Eun Lee, Byung Kwan Jin, Bong-Hee Lee & Ja-Hyun Baik. (2006) The Dopamine D 2 Receptor Regulates the Development of Dopaminergic Neurons via Extracellular Signal-Regulated Kinase and Nurr1 Activation . The Journal of Neuroscience 26:17, pages 4567-4576.
Crossref
L de Léséleuc & F Denis. (2005) Inhibition of apoptosis by Nur77 through NF-κB activity modulation. Cell Death & Differentiation 13:2, pages 293-300.
Crossref
M Messager, C Carrière, X Bertagna & Y de Keyzer. (2006) RT-PCR analysis of corticotroph-associated genes expression in carcinoid tumours in the ectopic-ACTH syndrome. European Journal of Endocrinology 154:1, pages 159-166.
Crossref
Timothy J. Cole. 2006. 269 300 .
Christian S Hinrichs, Douglas C Palmer, Steven A Rosenberg & Nicholas P Restifo. (2005) Glucocorticoids Do Not Inhibit Antitumor Activity of Activated CD8+ T Cells. Journal of Immunotherapy 28:6, pages 517-524.
Crossref
Izabela Kochel, Andrzej Rapak, Ewa Ziolo & Leon Strzadala. (2005) Nur77 nuclear import and its NBRE-binding activity in thymic lymphoma cells are regulated by different mechanisms sensitive to FK506 or HA1004. Biochemical and Biophysical Research Communications 334:4, pages 1102-1106.
Crossref
Flavia Q. Pirih, Tara L. Aghaloo, Olga Bezouglaia, Jeanne M. Nervina & Sotirios Tetradis. (2005) Parathyroid hormone induces the NR4A family of nuclear orphan receptors in vivo. Biochemical and Biophysical Research Communications 332:2, pages 494-503.
Crossref
Christine Martens, Steve Bilodeau, Mario Maira, Yves Gauthier & Jacques Drouin. (2005) Protein-Protein Interactions and Transcriptional Antagonism between the Subfamily of NGFI-B/Nur77 Orphan Nuclear Receptors and Glucocorticoid Receptor. Molecular Endocrinology 19:4, pages 885-897.
Crossref
Eric Batsché, Pandelis Moschopoulos, Julien Desroches, Steve Bilodeau & Jacques Drouin. (2005) Retinoblastoma and the Related Pocket Protein p107 Act as Coactivators of NeuroD1 to Enhance Gene Transcription. Journal of Biological Chemistry 280:16, pages 16088-16095.
Crossref
E. Ronald de Kloet, Mathias Schmidt & Onno C. Meijer. 2005. Handbook of Stress and the Brain - Part 1: The Neurobiology of Stress. Handbook of Stress and the Brain - Part 1: The Neurobiology of Stress 265 294 .
Kirsten-Berit Abel & Joseph A. Majzoub. 2005. Handbook of Stress and the Brain - Part 1: The Neurobiology of Stress. Handbook of Stress and the Brain - Part 1: The Neurobiology of Stress 79 94 .
C. Roumestan, C. Gougat, D. Jaffuel & M. Mathieu. (2004) Les glucocorticoïdes et leur récepteur : mécanismes d'action et conséquences cliniques. La Revue de Médecine Interne 25:9, pages 636-647.
Crossref
MASSIMO U. MARTINO, SALVATORE ALESCI, GEORGE P. CHROUSOS & TOMOSHIGE KINO. (2004) Interaction of the Glucocorticoid Receptor and the Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII): Implications for the Actions of Glucocorticoids on Glucose, Lipoprotein, and Xenobiotic Metabolism. Annals of the New York Academy of Sciences 1024:1, pages 72-85.
Crossref
Myunggon Ko, Jiho Jang, Jeongeun Ahn, Kyuyoung Lee, Heekyoung Chung, Sung H. Jeon & Rho H. Seong. (2004) T Cell Receptor Signaling Inhibits Glucocorticoid-induced Apoptosis by Repressing the SRG3 Expression via Ras Activation. Journal of Biological Chemistry 279:21, pages 21903-21915.
Crossref
Damian Kovalovsky, Marcelo Paez Pereda, Marta Labeur, Ulrich Renner, Florian Holsboer, Günter K Stalla & Eduardo Arzt. (2004) Nur77 induction and activation are necessary for interleukin-1 stimulation of proopiomelanocortin in AtT-20 corticotrophs. FEBS Letters 563:1-3, pages 229-233.
Crossref
Massimo U. De Martino, Nisan Bhattachryya, Salvatore Alesci, Takamasa Ichijo, George P. Chrousos & Tomoshige Kino. (2004) The Glucocorticoid Receptor and the Orphan Nuclear Receptor Chicken Ovalbumin Upstream Promoter-Transcription Factor II Interact with and Mutually Affect Each Other’s Transcriptional Activities: Implications for Intermediary Metabolism. Molecular Endocrinology 18:4, pages 820-833.
Crossref
Maxine K Turney, Wendell E Nicholson & William J Kovacs. (2004) Gene expression phenotyping of an ACTH-producing small cell lung cancer line. Molecular and Cellular Endocrinology 219:1-2, pages 105-113.
Crossref
Katia P. Karalis, Maria Venihaki, Jie Zhao, Lilian E. van Vlerken & Christina Chandras. (2004) NF-κB Participates in the Corticotropin-releasing, Hormone-induced Regulation of the Pituitary Proopiomelanocortin Gene. Journal of Biological Chemistry 279:12, pages 10837-10840.
Crossref
Rula A. Abbud, Robert Kelleher & Shlomo Melmed. (2004) Cell-Specific Pituitary Gene Expression Profiles after Treatment with Leukemia Inhibitory Factor Reveal Novel Modulators for Proopiomelanocortin Expression. Endocrinology 145:2, pages 867-880.
Crossref
Ji-Woong Choi, Sang Chul Park, Gyeong Hoon Kang, Jun O. Liu & Hong-Duk Youn. (2004) Nur77 Activated by Hypoxia-Inducible Factor-1α Overproduces Proopiomelanocortin in von Hippel-Lindau-Mutated Renal Cell Carcinoma. Cancer Research 64:1, pages 35-39.
Crossref
Mario Maira, Catherine Couture, Gwendal Le Martelot, Anne-Marie Pulichino, Steve Bilodeau & Jacques Drouin. (2003) The T-box Factor Tpit Recruits SRC/p160 Co-activators and Mediates Hormone Action. Journal of Biological Chemistry 278:47, pages 46523-46532.
Crossref
Jesse J Savage, Benjamin C Yaden, Parinda Kiratipranon & Simon J Rhodes. (2003) Transcriptional control during mammalian anterior pituitary development. Gene 319, pages 1-19.
Crossref
Karolien De Bosscher, Wim Vanden Berghe & Guy Haegeman. (2003) The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression. Endocrine Reviews 24:4, pages 488-522.
Crossref
Peter Ordentlich, Yingzhuo Yan, Sihong Zhou & Richard A. Heyman. (2003) Identification of the Antineoplastic Agent 6-Mercaptopurine as an Activator of the Orphan Nuclear Hormone Receptor Nurr1. Journal of Biological Chemistry 278:27, pages 24791-24799.
Crossref
Suzanne Crowley. (2003) Inhaled glucocorticoids and adrenal function: an update. Paediatric Respiratory Reviews 4:2, pages 153-161.
Crossref
Min Li-Weber & Peter H. Krammer. (2003) Function and regulation of the CD95 (APO-1/Fas) ligand in the immune system. Seminars in Immunology 15:3, pages 145-157.
Crossref
Tomoshige Kino, Massimo U De Martino, Evangelia Charmandari, Marco Mirani & George P Chrousos. (2003) Tissue glucocorticoid resistance/hypersensitivity syndromes. The Journal of Steroid Biochemistry and Molecular Biology 85:2-5, pages 457-467.
Crossref
Catherine E. Keegan & Sally A. Camper. (2003) Mouse knockout solves endocrine puzzle and promotes new pituitary lineage model. Genes & Development 17:6, pages 677-682.
Crossref
Anne-Marie Pulichino, Sophie Vallette-Kasic, Judy Peih-Ying Tsai, Catherine Couture, Yves Gauthier & Jacques Drouin. (2003) Tpit determines alternate fates during pituitary cell differentiation. Genes & Development 17:6, pages 738-747.
Crossref
Maria Nudi, Éric Batsché & Jacques Drouin. 2003. The Acth Axis: Pathogenesis, Diagnosis and Treatment. The Acth Axis: Pathogenesis, Diagnosis and Treatment 1 27 .
Damián Kovalovsky, Damián Refojo, Ana Clara Liberman, Daniel Hochbaum, Marcelo Paez Pereda, Omar A. Coso, Günter K. Stalla, Florian Holsboer & Eduardo Arzt. (2002) Activation and Induction of NUR77/NURR1 in Corticotrophs by CRH/cAMP: Involvement of Calcium, Protein Kinase A, and MAPK Pathways. Molecular Endocrinology 16:7, pages 1638-1651.
Crossref
Alessandra Gennari, Rob Bleumink, Barbara Viviani, Corrado Lodovico Galli, Marina Marinovich, Raymond Pieters & Emanuela Corsini. (2002) Identification by DNA Macroarray of nur77 as a Gene Induced by Di-n-butyltin Dichloride: Its Role in Organotin-Induced Apoptosis. Toxicology and Applied Pharmacology 181:1, pages 27-31.
Crossref
Felix Beuschlein & Gary D. Hammer. (2002) Ectopic pro-opiomelanocortin syndrome. Endocrinology and Metabolism Clinics of North America 31:1, pages 191-234.
Crossref
Vincent Laudet & Hinrich Gronemeyer. 2002. The Nuclear Receptor FactsBook. The Nuclear Receptor FactsBook 401 410 .
Vincent Laudet & Hinrich Gronemeyer. 2002. The Nuclear Receptor FactsBook. The Nuclear Receptor FactsBook 345 367 .
William J. Kovacs. 2002. Cushing’s Syndrome. Cushing’s Syndrome 185 200 .
Marie-Laure Raffin-Sanson, Yves de Keyzer & Xavier Bertagna. 2002. Cushing’s Syndrome. Cushing’s Syndrome 127 183 .
Yutaka Oki. 2002. Cushing’s Syndrome. Cushing’s Syndrome 1 28 .
Jean Bousquet, Paul van Cauwenberge & Nikolai Khaltaev. (2001) Allergic Rhinitis and Its Impact on Asthma. Journal of Allergy and Clinical Immunology 108:5, pages S147-S334.
Crossref
Marcelo Páez-Pereda, Damian Kovalovsky, Ursula Hopfner, Marily Theodoropoulou, Uberto Pagotto, Eberhard Uhl, Marco Losa, Johanna Stalla, Yvonne Grübler, Cristina Missale, Eduardo Arzt & Günter K. Stalla. (2001) Retinoic acid prevents experimental Cushing syndrome. Journal of Clinical Investigation 108:8, pages 1123-1131.
Crossref
Marcelo Páez-Pereda, Damian Kovalovsky, Ursula Hopfner, Marily Theodoropoulou, Uberto Pagotto, Eberhard Uhl, Marco Losa, Johanna Stalla, Yvonne Grübler, Cristina Missale, Eduardo Arzt & Günter K. Stalla. (2001) Retinoic acid prevents experimental Cushing syndrome. Journal of Clinical Investigation 108:8, pages 1123-1131.
Crossref
D Refojo, AC Liberman, F Holsboer & E Arzt. (2001) Transcription factor‐mediated molecular mechanisms involved in the functional cross‐talk between cytokines and glucocorticoids. Immunology & Cell Biology 79:4, pages 385-394.
Crossref
Jianxiang Liu, Chijen Lin, Anatoli Gleiberman, Kenneth A. Ohgi, Thomas Herman, Hsiang-Po Huang, Ming-Jer Tsai & Michael G. Rosenfeld. (2001) Tbx19 , a tissue-selective regulator of POMC gene expression . Proceedings of the National Academy of Sciences 98:15, pages 8674-8679.
Crossref
Evelyn P. Murphy, Alice McEvoy, Orla M. Conneely, Barry Bresnihan & Oliver FitzGerald. (2001) Involvement of the nuclear orphan receptor NURR1 in the regulation of corticotropin-releasing hormone expression and actions in human inflammatory arthritis. Arthritis & Rheumatism 44:4, pages 782-793.
Crossref
André Lacroix, Nina N′Diaye, Johanne Tremblay & Pavel Hamet. (2001) Ectopic and Abnormal Hormone Receptors in Adrenal Cushing’s Syndrome*. Endocrine Reviews 22:1, pages 75-110.
Crossref
Achille Gravanis & Andrew N. Margioris. 2001. Adrenal Disorders. Adrenal Disorders 59 70 .
Corinne Bousquet, Maria Chiara Zatelli & Shlomo Melmed. (2000) Direct regulation of pituitary proopiomelanocortin by STAT3 provides a novel mechanism for immuno-neuroendocrine interfacing. Journal of Clinical Investigation 106:11, pages 1417-1425.
Crossref
Geneviève Beaudry, Marie-Claire Langlois, Isabelle Weppe, Claude Rouillard & Daniel Lévesque. (2002) Contrasting Patterns and Cellular Specificity of Transcriptional Regulation of the Nuclear Receptor Nerve Growth Factor-Inducible B by Haloperidol and Clozapine in the Rat Forebrain. Journal of Neurochemistry 75:4, pages 1694-1702.
Crossref
Inga-Maj Johansson, Per Wester, Michaela Háková, WeiGang Gu, Jonathan R. Seckl & Tommy Olsson. (2000) Early and delayed induction of immediate early gene expression in a novel focal cerebral ischemia model in the rat. European Journal of Neuroscience 12:10, pages 3615-3625.
Crossref
DANY JAFFUEL, PASCAL DEMOLY, CLAIRE GOUGAT, PATRICK BALAGUER, GISÈLE MAUTINO, PHILIPPE GODARD, JEAN BOUSQUET & MARC MATHIEU. (2000) Transcriptional Potencies of Inhaled Glucocorticoids. American Journal of Respiratory and Critical Care Medicine 162:1, pages 57-63.
Crossref
Jonathan D. AshwellFrank W. M. LuMelanie S. Vacchio. (2000) Glucocorticoids in T Cell Development and Function. Annual Review of Immunology 18:1, pages 309-345.
Crossref
Uma R. Chandran & Donald B. DeFranco. 2000. Gene Engineering in Endocrinology. Gene Engineering in Endocrinology 87 97 .
Jeffrey C Webster & John A Cidlowski. (1999) Mechanisms of Glucocorticoid-receptor-mediated Repression of Gene Expression. Trends in Endocrinology & Metabolism 10:10, pages 396-402.
Crossref
Vincent Giguère. (1999) Orphan Nuclear Receptors: From Gene to Function*. Endocrine Reviews 20:5, pages 689-725.
Crossref
Christophe E. Pierreux, John Stafford, Dominique Demonte, Donald K. Scott, Jean Vandenhaute, Richard M. O’Brien, Daryl K. Granner, Guy G. Rousseau & Frederic P. Lemaigre. (1999) Antiglucocorticoid activity of hepatocyte nuclear factor-6. Proceedings of the National Academy of Sciences 96:16, pages 8961-8966.
Crossref
Jacques J. Tremblay & Robert S. Viger. (1999) Transcription Factor GATA-4 Enhances Müllerian Inhibiting Substance Gene Transcription through a Direct Interaction with the Nuclear Receptor SF-1. Molecular Endocrinology 13:8, pages 1388-1401.
Crossref
Yutaka Ueda, Shuji Bandoh, Jiro Fujita, Makoto Sato, Yasufumi Yamaji & Jiro Takahara. (1999) Expression of Nerve Growth Factor–Induced Clone B Subfamily and Pro-opiomelanocortin Gene in Lung Cancer Cell Lines. American Journal of Respiratory Cell and Molecular Biology 20:6, pages 1319-1325.
Crossref
P. L. M. Dahia & A. B. Grossman. (1999) The Molecular Pathogenesis of Corticotroph Tumors. Endocrine Reviews 20:2, pages 136-155.
Crossref
A. Picon, X. Bertagna & Y. de Keyzer. (1999) Analysis of proopiomelanocortin gene transcription mechanisms in bronchial tumour cells. Molecular and Cellular Endocrinology 147:1-2, pages 93-102.
Crossref
Dark Amsen & Ada M. Kruisbeek. (1998) Thymocyte selection: not by TCR alone. Immunological Reviews 165:1, pages 209-229.
Crossref
Holger M Reichardt, Klaus H Kaestner, Jan Tuckermann, Oliver Kretz, Oliver Wessely, Rudolf Bock, Peter Gass, Wolfgang Schmid, Peter Herrlich, Peter Angel & Günther Schütz. (1998) DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival. Cell 93:4, pages 531-541.
Crossref
Jacques Drouin, Mario Maira & Alexandre Philips. (1998) Novel mechanism of action for Nur77 and antagonism by glucocorticoids: A convergent mechanism for CRH activation and glucocorticoid repression of POMC gene transcription. The Journal of Steroid Biochemistry and Molecular Biology 65:1-6, pages 59-63.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.