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Research Article

The Level of Intracellular Glutathione Is a Key Regulator for the Induction of Stress-Activated Signal Transduction Pathways Including Jun N-Terminal Protein Kinases and p38 Kinase by Alkylating Agents

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Pages 4792-4800 | Received 02 Dec 1996, Accepted 28 Apr 1997, Published online: 29 Mar 2023

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Crossref
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Ross B Mikkelsen & Peter Wardman. (2003) Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms. Oncogene 22:37, pages 5734-5754.
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Danyelle M. Townsend, Kenneth D. Tew & Haim Tapiero. (2003) The importance of glutathione in human disease. Biomedicine & Pharmacotherapy 57:3-4, pages 145-155.
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Ke-Qing Zhu. (2003) Involvement of ATM/ATR-p38 MAPK cascade in MNNG induced G1-S arrest. World Journal of Gastroenterology 9:9, pages 2073.
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Crossref
Diana M. Toivola, Qin Zhou, Luc S. English & M. Bishr Omary. (2002) Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells. Molecular Biology of the Cell 13:6, pages 1857-1870.
Crossref
Teresa A. Doggett, John T. Swarthout, Stephen C. JefcoatJr.Jr., Dagmar Wilhelm, Andreas Dieckmann, Peter Angel & Nicola C. Partridge. (2002) Parathyroid Hormone Inhibits c-Jun N-Terminal Kinase Activity in Rat Osteoblastic Cells by a Protein Kinase A-Dependent Pathway. Endocrinology 143:5, pages 1880-1888.
Crossref
Subramaniam Jayanthi, Michael T. McCoy, Bruce Ladenheim & Jean Lud Cadet. (2002) Methamphetamine Causes Coordinate Regulation of Src, Cas, Crk, and the Jun N-Terminal Kinase–Jun Pathway. Molecular Pharmacology 61:5, pages 1124-1131.
Crossref
Yousin Suh. (2002) Cell signaling in aging and apoptosis. Mechanisms of Ageing and Development 123:8, pages 881-890.
Crossref
Nam-On Ku, M. Bishr Omary & Salman Azhar. (2002) Keratin 8 Phosphorylation by p38 Kinase Regulates Cellular Keratin Filament Reorganization. Journal of Biological Chemistry 277:13, pages 10775-10782.
Crossref
Maria Enrica Fracasso, Luigi Perbellini, Silvia Soldà, Giorgio Talamini & Paola Franceschetti. (2002) Lead induced DNA strand breaks in lymphocytes of exposed workers: role of reactive oxygen species and protein kinase C. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 515:1-2, pages 159-169.
Crossref
Öztürk Özdemir, Hüseyin Eray Bulut, Mehmet Korkmaz, Reyhan E&gcaron;ilmez & Atilla Atalay. (2002) Treatment of Ethylnitrosourea Induced Lymphocyte Hyperproliferation by DNA Hypomethylation in the Rat Colon.. CYTOLOGIA 67:2, pages 139-144.
Crossref
Wulf Dröge. (2002) Free Radicals in the Physiological Control of Cell Function. Physiological Reviews 82:1, pages 47-95.
Crossref
Tertia D. Purves & David R. Tomlinson. 2002. Neurobiology of Diabetic Neuropathy. Neurobiology of Diabetic Neuropathy 83 114 .
Irfan Rahman, Peter S. Gilmour, Luis Albert Jimenez & William MacNee. 2002. Oxygen/Nitrogen Radicals: Cell Injury and Disease. Oxygen/Nitrogen Radicals: Cell Injury and Disease 239 248 .
Ashok Gupta, Brent Butts, Kevin A. Kwei, Katerina Dvorakova, Steven P. Stratton, Margaret M. Briehl & G.Tim Bowden. (2001) Attenuation of catalase activity in the malignant phenotype plays a functional role in an in vitro model for tumor progression. Cancer Letters 173:2, pages 115-125.
Crossref
Audrey P. Gasch, Mingxia Huang, Sandra Metzner, David Botstein, Stephen J. Elledge & Patrick O. Brown. (2001) Genomic Expression Responses to DNA-damaging Agents and the Regulatory Role of the Yeast ATR Homolog Mec1p. Molecular Biology of the Cell 12:10, pages 2987-3003.
Crossref
Yoon-Ju Han, Young-Guen Kwon, Hun-Taeg Chung, Sung-Ki Lee, Richard L. Simmons, Timothy R. Billiar & Young-Myeong Kim. (2001) Antioxidant Enzymes Suppress Nitric Oxide Production through the Inhibition of NF-κB Activation: Role of H2O2 and Nitric Oxide in Inducible Nitric Oxide Synthase Expression in Macrophages. Nitric Oxide 5:5, pages 504-513.
Crossref
Maribel Parra, Mercè Jardı́, Magdalena Koziczak, Yoshikuni Nagamine & Pura Muñoz-Cánoves. (2001) p53 Phosphorylation at Serine 15 Is Required for Transcriptional Induction of the Plasminogen Activator Inhibitor-1 (PAI-1) Gene by the Alkylating AgentN-Methyl-N′-nitro-N-nitrosoguanidine. Journal of Biological Chemistry 276:39, pages 36303-36310.
Crossref
D.Margriet Ouwens, Daniel S. Gomes de Mesquita, Jeroen Dekker & J.Antonie Maassen. (2001) Hyperosmotic stress activates the insulin receptor in CHO cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1540:2, pages 97-106.
Crossref
Jun Yang & Penelope J. Duerksen-Hughes. (2001) Activation of a p53-independent, Sphingolipid-mediated Cytolytic Pathway in p53-negative Mouse Fibroblast Cells Treated with N-Methyl-N-nitro-N-nitrosoguanidine. Journal of Biological Chemistry 276:29, pages 27129-27135.
Crossref
Robert C. Cumming, Jeff Lightfoot, Kristin Beard, Hagop Youssoufian, Peter J. O'Brien & Manuel Buchwald. (2001) Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1. Nature Medicine 7:7, pages 814-820.
Crossref
Alexander Meves, Sibylle N. Stock, Astrid Beyerle, Mark R. Pittelkow & Dominik Peus. (2001) H2O2 mediates oxidative stress-induced epidermal growth factor receptor phosphorylation. Toxicology Letters 122:3, pages 205-214.
Crossref
Guliang Wang, Yingnian Yu, Xingruo Chen & Haiyang Xie. (2001) Low concentration N-methyl-N′-nitro-N-nitrosoguanidine activates DNA polymerase-β expression via cyclic-AMP-protein kinase A-cAMP response element binding protein pathway. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 478:1-2, pages 177-184.
Crossref
Ebba U. Kurz, Susan P.C. Cole & Roger G. Deeley. (2001) Identification of DNA–Protein Interactions in the 5′ Flanking and 5′ Untranslated Regions of the Human Multidrug Resistance Protein (MRP1) Gene: Evaluation of a Putative Antioxidant Response Element/AP-1 Binding Site. Biochemical and Biophysical Research Communications 285:4, pages 981-990.
Crossref
Corinne Aubel, Stéphanie Dehez, Hervé Chabanon, Catherine Seva, Marc Ferrara & Patrick Brachet. (2001) Activation of c-Jun N-terminal kinase 1 (JNK-1) after amino acid deficiency in HeLa cells. Cellular Signalling 13:6, pages 417-423.
Crossref
Valerie M Hudson. (2001) Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation. Free Radical Biology and Medicine 30:12, pages 1440-1461.
Crossref
Christine L Hammond, Thomas K Lee & Nazzareno Ballatori. (2001) Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes. Journal of Hepatology 34:6, pages 946-954.
Crossref
Lijiang Shen & Alex Sevanian. (2001) OxLDL induces macrophage γ-GCS-HS protein expression: a role for oxLDL-associated lipid hydroperoxide in GSH synthesis. Journal of Lipid Research 42:5, pages 813-823.
Crossref
Yi-Rong Chen, Anju Shrivastava & Tse-Hua Tan. (2001) Down-regulation of the c-Jun N-terminal kinase (JNK) phosphatase M3/6 and activation of JNK by hydrogen peroxide and pyrrolidine dithiocarbamate. Oncogene 20:3, pages 367-374.
Crossref
S. Hashimoto, Y. Gon, K. Matsumoto, I. Takeshita, T. Machino & T. Horie. (2001) Intracellular glutathione regulates tumour necrosis factor-α-induced p38 MAP kinase activation and RANTES production by human bronchial epithelial cells. Clinical & Experimental Allergy 31:1, pages 144-151.
Crossref
S. Hashimoto, Y. Gon, K. Matsumoto, I. Takeshita, T. Machino & T. Horie. (2001) Intracellular glutathione regulates tumour necrosis factor-alpha-induced p38 MAP kinase activation and RANTES production by human bronchial epithelial cells. Clinical <html_ent glyph="@amp;" ascii="&"/> Experimental Allergy 31:1, pages 144-151.
Crossref
Shu Hashimoto, Yasuhiro Gon, Ken Matsumoto, Ikuko Takeshita & Takashi Horie. (2001) N-acetylcysteine attenuates TNF-α-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells. British Journal of Pharmacology 132:1, pages 270-276.
Crossref
Hasem Habelhah & Ze'ev Ronai. 2001. Protein Adaptations and Signal Transduction. Protein Adaptations and Signal Transduction 253 262 .
Ke Xu & Paul J Thornalley. (2001) Involvement of glutathione metabolism in the cytotoxicity of the phenethyl isothiocyanate and its cysteine conjugate to human leukaemia cells in vitro11Abbreviations: BSO, l-buthionine sulphoximine; DNP-SG, S-2,4-dinitrophenylglutathione; DTT, dithiothreitol; GST, glutathione S-transferase; HL60, human leukaemia 60; JNK1, c-Jun N-terminal kinase 1; ML-1, human myeloblastic leukaemia-1; PEITC, phenethyl isothiocyanate; PETC, N-phenethylthiocarbamoyl; PETC-Cys, S-(N-phenethylthiocarbamoyl)cysteine; PETC-SG, S-(N-phenethylthiocarbamoyl)glutathione; and Z-VAD-fmk, N-benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone.. Biochemical Pharmacology 61:2, pages 165-177.
Crossref
Theo van Laar, Theo Schouten, Alex J. van der Eb & Carrol Terleth. (2001) Induction of the SAPK activatorMIG-6 by the alkylating agent methyl methanesulfonate. Molecular Carcinogenesis 31:2, pages 63-67.
Crossref
Yannick Morel, Xavier Coumoul, Antoine Nalpas & Robert Barouki. (2000) Nuclear Factor I/CCAAT Box Transcription Factor trans -Activating Domain Is a Negative Sensor of Cellular Stress . Molecular Pharmacology 58:6, pages 1239-1246.
Crossref
Michael M. Awad, Herve Enslen, Joan M. Boylan, Roger J. Davis & Philip A. Gruppuso. (2000) Growth Regulation via p38 Mitogen-activated Protein Kinase in Developing Liver. Journal of Biological Chemistry 275:49, pages 38716-38721.
Crossref
W. Jia & J. Zhang. (2000) Water stress-induced abscisic acid accumulation in relation to reducing agents and sulfhydryl modifiers in maize plant. Plant, Cell and Environment 23:12, pages 1389-1395.
Crossref
Wei Cui, Eugenia M. Yazlovitskaya, Matthew S. Mayo, Jill C. Pelling & Diane L. Persons. (2000) Cisplatin-induced response of c-jun N-terminal kinase 1 and extracellular signal-regulated protein kinases 1 and 2 in a series of cisplatin-resistant ovarian carcinoma cell lines. Molecular Carcinogenesis 29:4, pages 219-228.
Crossref
Jeonghyeon Park & Alice Y.-C. Liu. (2000) Pervanadate induces the hyperphosphorylation but not the activation of human heat shock factor 1. Journal of Cellular Physiology 185:3, pages 348-357.
Crossref
Marie-Jeanne Pillaire, Angel R. Nebreda & Jean-Marie Darbon. (2000) Cisplatin and UV Radiation Induce Activation of the Stress-Activated Protein Kinase p38γ in Human Melanoma Cells. Biochemical and Biophysical Research Communications 278:3, pages 724-728.
Crossref
Hideaki Kondo, Satoko Mori, Hirofumi Takino, Hiroshi Kijima, Hironori Yamasaki, Masako Ozaki, Iida Tetsuya, Yoshishige Urata, Takahiro Abe, Yasunori Sera, Kenji Yamakawa, Eiji Kawasaki, Yoshihiko Yamaguchi, Takahito Kondo & Katsumi Eguchi. (2000) Attenuation of Expression of γ-Glutamylcysteine Synthetase by Ribozyme Transfection Enhance Insulin Secretion by Pancreatic β Cell Line, MIN6. Biochemical and Biophysical Research Communications 278:1, pages 236-240.
Crossref
Steffen P. Hehner, Raoul Breitkreutz, George Shubinsky, Heike Unsoeld, Klaus Schulze-Osthoff, M. Lienhard Schmitz & Wulf Dröge. (2000) Enhancement of T Cell Receptor Signaling by a Mild Oxidative Shift in the Intracellular Thiol Pool. The Journal of Immunology 165:8, pages 4319-4328.
Crossref
Irfan Rahman. (2000) Regulation of nuclear factor-κB, activator protein-1, and glutathione levels by tumor necrosis factor-α and dexamethasone in alveolar epithelial cells. Biochemical Pharmacology 60:8, pages 1041-1049.
Crossref
Geetha M. Habib, Zheng-zheng Shi, Ching-nan Ou, Geeta Kala, Subbarao V. Kala & Michael W. Lieberman. (2000) Altered Gene Expression in the Liver ofγ-Glutamyl Transpeptidase–Deficient Mice. Hepatology 32:3, pages 556-562.
Crossref
Maribel ParraFrederic Lluı́sFrancesc MirallesCarme CaellesPura Muñoz-Cánoves. (2000) The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG. Blood 96:4, pages 1415-1424.
Crossref
Maribel ParraFrederic Lluı́sFrancesc MirallesCarme CaellesPura Muñoz-Cánoves. (2000) The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG. Blood 96:4, pages 1415-1424.
Crossref
Shawn B. Bratton, Serrine S. Lau & Terrence J. Monks. (2000) The Putative Benzene Metabolite 2,3,5-Tris(glutathion- S -yl)hydroquinone Depletes Glutathione, Stimulates Sphingomyelin Turnover, and Induces Apoptosis in HL-60 Cells . Chemical Research in Toxicology 13:7, pages 550-556.
Crossref
Philip E. Mirkes, Kathleen L. Wilson & Leanne M. Cornel. (2000) Teratogen-induced activation of ERK, JNK, and p38 MAP kinases in early postimplantation murine embryos. Teratology 62:1, pages 14-25.
Crossref
Michele Mietus-Snyder, Maya S. Gowri & Robert E. Pitas. (2000) Class A Scavenger Receptor Up-regulation in Smooth Muscle Cells by Oxidized Low Density Lipoprotein. Journal of Biological Chemistry 275:23, pages 17661-17670.
Crossref
Chew-Wun Wu, Anna F.-Y. Li, Chin-Wen Chi, Chen Lung Huang, King-Han Shen, Wing-Yiu Liu & Wen-chang Lin. (2000) Human Gastric Cancer Kinase Profile and Prognostic Significance of MKK4 Kinase. The American Journal of Pathology 156:6, pages 2007-2015.
Crossref
Irfan Rahman & William MacNee. (2000) Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. Free Radical Biology and Medicine 28:9, pages 1405-1420.
Crossref
Rong Yu, Sandhya Mandlekar, Tse-Hua Tan & A.-N.Tony Kong. (2000) Activation of p38 and c-Jun N-terminal Kinase Pathways and Induction of Apoptosis by Chelerythrine Do Not Require Inhibition of Protein Kinase C. Journal of Biological Chemistry 275:13, pages 9612-9619.
Crossref
Judy L. BoltonMichael A. TrushTrevor M. PenningGlenn DryhurstTerrence J. Monks. (2000) Role of Quinones in Toxicology. Chemical Research in Toxicology 13:3, pages 135-160.
Crossref
Helen L Reeves, Clare L Dack, Matthew Peak, Alastair D Burt & Christopher P Day. (2000) Stress-activated protein kinases in the activation of rat hepatic stellate cells in culture. Journal of Hepatology 32:3, pages 465-472.
Crossref
Guillermo Fernández, Maria-Pau Mena, Anna Arnau, Olga Sánchez, Maria Soley & Ignasi Ramírez. (2000) Immobilization stress induces c-Fos accumulation in liver. Cell Stress & Chaperones 5:4, pages 306.
Crossref
Irfan Rahman. (1999) Inflammation and the Regulation of Glutathione Level in Lung Epithelial Cells. Antioxidants & Redox Signaling 1:4, pages 425-447.
Crossref
Ashok Gupta, Sabine F. Rosenberger & G. Tim Bowden. (1999) Increased ROS levels contribute to elevated transcription factor and MAP kinase activities in malignantly progressed mouse keratinocyte cell lines. Carcinogenesis 20:11, pages 2063-2073.
Crossref
Victor Adler, Zhimin Yin, Kenneth D Tew & Ze'ev Ronai. (1999) Role of redox potential and reactive oxygen species in stress signaling. Oncogene 18:45, pages 6104-6111.
Crossref
Vincent Castagné & Peter G.H. Clarke. (1999) Inhibitors of mitogen-activated protein kinases protect axotomized developing neurons. Brain Research 842:1, pages 215-219.
Crossref
Jung-Mi Kim, Jung-Dae Kim, Rina Yu, Byung-Sam Kim, Mi-Kyung Shin & In-Seob Han. (1999) Effects of capsaicin on induction of c-jun proto-oncogene expression in Fisher-344 rats by N-methyl-N′-nitro-N-nitrosoguanidine. Cancer Letters 142:2, pages 155-160.
Crossref
Sunil K Manna, M Tien Kuo & Bharat B Aggarwal. (1999) Overexpression of γ-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1. Oncogene 18:30, pages 4371-4382.
Crossref
Anne Bouloumié, Takeshi Marumo, Max Lafontan & Rudi Busse. (1999) Leptin induces oxidative stress in human endothelial cells. The FASEB Journal 13:10, pages 1231-1238.
Crossref
Kenneth D. Tew & Ze’ev Ronai. (1999) GST function in drug and stress response. Drug Resistance Updates 2:3, pages 143-147.
Crossref
Dominik Peus, Remus A. Vasa, Astrid Beyerle, Alexander Meves, Carsten Krautmacher & Mark R. Pittelkow. (1999) UVB Activates ERK1/2 and p38 Signaling Pathways via Reactive Oxygen Species in Cultured Keratinocytes. Journal of Investigative Dermatology 112:5, pages 751-756.
Crossref
Shu Hashimoto, Ken Matsumoto, Yasuhiro Gon, Sachiko Furuichi, Shuichiro Maruoka, Ikuko Takeshita, Kiichi Hirota, Junji Yodoi & Takashi Horie. (1999) Thioredoxin Negatively Regulates p38 MAP Kinase Activation and IL-6 Production by Tumor Necrosis Factor-α. Biochemical and Biophysical Research Communications 258:2, pages 443-447.
Crossref
Timothy P. DaltonHoward G. ShertzerAlvaro Puga. (1999) REGULATION OF GENE EXPRESSION BY REACTIVE OXYGEN. Annual Review of Pharmacology and Toxicology 39:1, pages 67-101.
Crossref
Toshinari Minamoto, Masayoshi Mai & Ze'ev Ronai. (1999) Environmental factors as regulators and effectors of multistep carcinogenesis. Carcinogenesis 20:4, pages 519-527.
Crossref
Naı̈ma Chikhi, Nathalie Holic, Georges Guellaen & Yannick Laperche. (1999) Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 122:4, pages 367-380.
Crossref
E.J Patten & M.J DeLong. (1999) Temporal Effects of the Detoxification Enzyme Inducer, Benzyl Isothiocyanate: Activation of c-Jun N-terminal Kinase Prior to the Transcription Factors AP-1 and NFκB. Biochemical and Biophysical Research Communications 257:1, pages 149-155.
Crossref
Pramod Pandey, Shalom Avraham, Andrew Place, Vijay Kumar, Pradip K. Majumder, Keding Cheng, Atsuko Nakazawa, Satya Saxena & Surender Kharbanda. (1999) Bcl-xL Blocks Activation of Related Adhesion Focal Tyrosine Kinase/Proline-rich Tyrosine Kinase 2 and Stress-activated Protein Kinase/c-Jun N-terminal Protein Kinase in the Cellular Response to Methylmethane Sulfonate. Journal of Biological Chemistry 274:13, pages 8618-8623.
Crossref
Axel Behrens, Maria Sibilia & Erwin F. Wagner. (1999) Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nature Genetics 21:3, pages 326-329.
Crossref
Ingrid Herr, Dagmar Wilhelm, Thomas B�hler, Peter Angel & Klaus-Michael Debatin. (1999) JNK/SAPK activity is not sufficient for anticancer therapy-induced apoptosis involving CD95-L, TRAIL and TNF-?. International Journal of Cancer 80:3, pages 417-424.
Crossref
B. Kaina, S. Haas, S. Grösch, T. Grombacher, J. Dosch, T. Biswas, I. Boldogh, S. Mitra & G. Fritz. 1999. Fundamentals for the Assessment of Risks from Environmental Radiation. Fundamentals for the Assessment of Risks from Environmental Radiation 289 300 .
Deming Wang, Xin Yu & Peter Brecher. (1998) Nitric Oxide and N-Acetylcysteine Inhibit the Activation of Mitogen-activated Protein Kinases by Angiotensin II in Rat Cardiac Fibroblasts. Journal of Biological Chemistry 273:49, pages 33027-33034.
Crossref
Yong J. Lee & Peter M. Corry. (1998) Metabolic Oxidative Stress-induced HSP70 Gene Expression Is Mediated through SAPK Pathway. Journal of Biological Chemistry 273:45, pages 29857-29863.
Crossref
Chandan K Sen. (1998) Redox Signaling and the Emerging Therapeutic Potential of Thiol Antioxidants. Biochemical Pharmacology 55:11, pages 1747-1758.
Crossref
Toren Finkel. (1998) Oxygen radicals and signaling. Current Opinion in Cell Biology 10:2, pages 248-253.
Crossref
Y Tony Ip & Roger J Davis. (1998) Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development. Current Opinion in Cell Biology 10:2, pages 205-219.
Crossref

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