40
Views
144
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Interaction between the Product of the Breast Cancer Susceptibility Gene BRCA2 and DSS1, a Protein Functionally Conserved from Yeast to Mammals

, , , , &
Pages 4633-4642 | Received 26 Mar 1999, Accepted 05 Apr 1999, Published online: 28 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Marius Boulos Faza, Stefan Kemmler & Vikram Govind Panse. (2010) Sem1. Nucleus 1:1, pages 12-17.
Read now
Derek J. Richard, Emma Bolderson & Kum Kum Khanna. (2009) Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis. Critical Reviews in Biochemistry and Molecular Biology 44:2-3, pages 98-116.
Read now
Julie S. Martin, Nicole Winkelmann, Mark I. R. Petalcorin, Michael J. McIlwraith & Simon J. Boulton. (2005) RAD-51-Dependent and -Independent Roles of a Caenorhabditis elegans BRCA2-Related Protein during DNA Double-Strand Break Repair. Molecular and Cellular Biology 25:8, pages 3127-3139.
Read now
Milorad Kojic, Qingwen Zhou, Michael Lisby & William K. Holloman. (2005) Brh2-Dss1 Interplay Enables Properly Controlled Recombination in Ustilago maydis. Molecular and Cellular Biology 25:7, pages 2547-2557.
Read now
Huimei Lu, Xu Guo, Xiangbing Meng, Jingmei Liu, Chris Allen, Justin Wray, Jac A. Nickoloff & Zhiyuan Shen. (2005) The BRCA2-Interacting Protein BCCIP Functions in RAD51 and BRCA2 Focus Formation and Homologous Recombinational Repair. Molecular and Cellular Biology 25:5, pages 1949-1957.
Read now
Shinobu Tsuzuki, Masayuki Towatari, Hidehiko Saito & Tariq Enver. (2000) Potentiation of GATA-2 Activity through Interactions with the Promyelocytic Leukemia Protein (PML) and the t(15;17)-Generated PML-Retinoic Acid Receptor α Oncoprotein. Molecular and Cellular Biology 20:17, pages 6276-6286.
Read now

Articles from other publishers (138)

Poonam Roshan, Sahiti Kuppa, Jenna R. Mattice, Vikas Kaushik, Rahul Chadda, Nilisha Pokhrel, Brunda R. Tumala, Aparna Biswas, Brian Bothner, Edwin Antony & Sofia Origanti. (2023) An Aurora B-RPA signaling axis secures chromosome segregation fidelity. Nature Communications 14:1.
Crossref
Ivana Nikolić, Jelena Samardžić, Strahinja Stevanović, Jovanka Miljuš-Đukić, Mira Milisavljević & Gordana Timotijević. (2023) CRISPR/Cas9-Targeted Disruption of Two Highly Homologous Arabidopsis thaliana DSS1 Genes with Roles in Development and the Oxidative Stress Response. International Journal of Molecular Sciences 24:3, pages 2442.
Crossref
Piero R. Bianco. (2022) OB-fold Families of Genome Guardians: A Universal Theme Constructed From the Small β-barrel Building Block. Frontiers in Molecular Biosciences 9.
Crossref
Kei-Ichiro Ishiguro. (2022) Sexually Dimorphic Properties in Meiotic Chromosome. Sexual Development, pages 1-11.
Crossref
Cécile Le Page, Setor Amuzu, Kurosh Rahimi, Walter Gotlieb, Jiannis Ragoussis & Patricia N. Tonin. (2021) Lessons learned from understanding chemotherapy resistance in epithelial tubo-ovarian carcinoma from BRCA1and BRCA2mutation carriers. Seminars in Cancer Biology 77, pages 110-126.
Crossref
Angelina Zheleva, Lola P. Camino, Nuria Fernández-Fernández, María García-Rubio, Peter Askjaer, Tatiana García-Muse & Andrés Aguilera. (2021) THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans . Journal of Cell Science 134:20.
Crossref
Sarah F. Ruidiaz, Jesper E. Dreier, Rasmus Hartmann‐Petersen & Birthe B. Kragelund. (2021) The disordered PCI ‐binding human proteins CSNAP and DSS1 have diverged in structure and function . Protein Science 30:10, pages 2069-2082.
Crossref
Hang Phuong Le, Wolf-Dietrich Heyer & Jie Liu. (2021) Guardians of the Genome: BRCA2 and Its Partners. Genes 12:8, pages 1229.
Crossref
Paul R. Andreassen, Joonbae Seo, Constanze Wiek & Helmut Hanenberg. (2021) Understanding BRCA2 Function as a Tumor Suppressor Based on Domain-Specific Activities in DNA Damage Responses. Genes 12:7, pages 1034.
Crossref
Ivana P. Nikolić, Sofija B. Nešić, Jelena T. Samardžić & Gordana S. Timotijević. (2021) Intrinsically disordered protein AtDSS1(V) participates in plant defense response to oxidative stress. Protoplasma 258:4, pages 779-792.
Crossref
Judit Jimenez-Sainz & Ryan B. Jensen. (2021) Imprecise Medicine: BRCA2 Variants of Uncertain Significance (VUS), the Challenges and Benefits to Integrate a Functional Assay Workflow with Clinical Decision Rules. Genes 12:5, pages 780.
Crossref
Ruifeng Fu, Chong Wang, Hongyu Shen, Jie Zhang, James D. Higgins & Wanqi Liang. (2020) Rice OsBRCA2 Is Required for DNA Double-Strand Break Repair in Meiotic Cells. Frontiers in Plant Science 11.
Crossref
Mayanka Awasthi, Kumari Sushmita, Manish Singh Kaushik, Peeyush Ranjan & Suneel Kateriya. (2020) Novel Modular Rhodopsins from Green Algae Hold Great Potential for Cellular Optogenetic Modulation Across the Biological Model Systems. Life 10:11, pages 259.
Crossref
Ajinkya S. KawalePatrick Sung. (2020) Mechanism and significance of chromosome damage repair by homologous recombination. Essays in Biochemistry 64:5, pages 779-790.
Crossref
Hang Phuong Le, Xiaoyan Ma, Jorge Vaquero, Megan Brinkmeyer, Fei Guo, Wolf-Dietrich Heyer & Jie Liu. (2020) DSS1 and ssDNA regulate oligomerization of BRCA2. Nucleic Acids Research 48:14, pages 7818-7833.
Crossref
Anup Kumar Singh & Xiaochun Yu. (2020) Tissue-Specific Carcinogens as Soil to Seed BRCA1/2-Mutant Hereditary Cancers. Trends in Cancer 6:7, pages 559-568.
Crossref
Kazumasa Takemoto, Naoki Tani, Yuki Takada-Horisawa, Sayoko Fujimura, Nobuhiro Tanno, Mariko Yamane, Kaho Okamura, Michihiko Sugimoto, Kimi Araki & Kei-ichiro Ishiguro. (2020) Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination. Cell Reports 31:8, pages 107686.
Crossref
Weixing ZhaoClaudia Wiese, Youngho KwonRobert Hromas & Patrick Sung. (2019) The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination. Annual Review of Biochemistry 88:1, pages 221-245.
Crossref
Eugenia Fraile-Bethencourt, Alberto Valenzuela-Palomo, Beatriz Díez-Gómez, María José Caloca, Susana Gómez-Barrero & Eladio A. Velasco. (2019) Minigene Splicing Assays Identify 12 Spliceogenic Variants of BRCA2 Exons 14 and 15. Frontiers in Genetics 10.
Crossref
Alberto Vicens & David Posada. (2018) Selective Pressures on Human Cancer Genes along the Evolution of Mammals. Genes 9:12, pages 582.
Crossref
Signe M. Schenstrøm, Caio A. Rebula, Michael H. Tatham, Ruth Hendus-Altenburger, Isabelle Jourdain, Ronald T. Hay, Birthe B. Kragelund & Rasmus Hartmann-Petersen. (2018) Expanded Interactome of the Intrinsically Disordered Protein Dss1. Cell Reports 25:4, pages 862-870.
Crossref
Eugenia Fraile-Bethencourt, Alberto Valenzuela-Palomo, Beatriz Díez-Gómez, Alberto Acedo & Eladio A. Velasco. (2018) Identification of Eight Spliceogenic Variants in BRCA2 Exon 16 by Minigene Assays. Frontiers in Genetics 9.
Crossref
Miriam Kolog Gulko, Gabriele Heinrich, Carina Gross, Blagovesta Popova, Oliver Valerius, Piotr Neumann, Ralf Ficner & Gerhard H. Braus. (2018) Sem1 links proteasome stability and specificity to multicellular development. PLOS Genetics 14:2, pages e1007141.
Crossref
S. Korolev. (2017) Advances in structural studies of recombination mediator proteins. Biophysical Chemistry 225, pages 27-37.
Crossref
Benjamin Rengstl, Sooji Kim, Claudia Döring, Christian Weiser, Julia Bein, Katrin Bankov, Marco Herling, Sebastian Newrzela, Martin-Leo Hansmann & Sylvia Hartmann. (2017) Small and big Hodgkin-Reed-Sternberg cells of Hodgkin lymphoma cell lines L-428 and L-1236 lack consistent differences in gene expression profiles and are capable to reconstitute each other. PLOS ONE 12:5, pages e0177378.
Crossref
Sanne R. Martens-de Kemp, Arjen Brink, Ida H. van der Meulen, Renée X. de Menezes, Dennis E. te Beest, C. René Leemans, Victor W. van Beusechem, Boudewijn J.M. Braakhuis & Ruud H. Brakenhoff. (2017) The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics. Molecular Cancer Therapeutics 16:3, pages 540-550.
Crossref
Mario Venza, Maria Visalli, Teresa Catalano, Concetta Beninati, Diana Teti & Isabella Venza. (2017) DSS1 promoter hypomethylation and overexpression predict poor prognosis in melanoma and squamous cell carcinoma patients. Human Pathology 60, pages 137-146.
Crossref
Jose Maria Carvajal-Gonzalez, Sonia Mulero-Navarro, Michael Smith & Marek Mlodzik. (2016) A Novel Frizzled-Based Screening Tool Identifies Genetic Modifiers of Planar Cell Polarity in Drosophila Wings . G3 Genes|Genomes|Genetics 6:12, pages 3963-3973.
Crossref
Olga Levin-Kravets, Neta Tanner, Noa Shohat, Ilan Attali, Tal Keren-Kaplan, Anna Shusterman, Shay Artzi, Alexander Varvak, Yael Reshef, Xiaojing Shi, Ori Zucker, Tamir Baram, Corine Katina, Inbar Pilzer, Shay Ben-Aroya & Gali Prag. (2016) A bacterial genetic selection system for ubiquitylation cascade discovery. Nature Methods 13:11, pages 945-952.
Crossref
Amélie Fradet-Turcotte, Justine Sitz, Damien Grapton & Alexandre Orthwein. (2016) BRCA2 functions: from DNA repair to replication fork stabilization. Endocrine-Related Cancer 23:10, pages T1-T17.
Crossref
Birthe B. Kragelund, Signe M. Schenstrøm, Caio A. Rebula, Vikram Govind Panse & Rasmus Hartmann-Petersen. (2016) DSS1/Sem1, a Multifunctional and Intrinsically Disordered Protein. Trends in Biochemical Sciences 41:5, pages 446-459.
Crossref
Pounami Samadder, Rakesh Aithal, Ondrej Belan & Lumir Krejci. (2016) Cancer TARGETases: DSB repair as a pharmacological target. Pharmacology & Therapeutics 161, pages 111-131.
Crossref
N. Sakaguchi & K. Maeda. 2016. 135 186 .
Feng Zhang, Jiazhong Shi, Chunjing Bian & Xiaochun Yu. (2015) Poly(ADP-Ribose) Mediates the BRCA2-Dependent Early DNA Damage Response. Cell Reports 13:4, pages 678-689.
Crossref
Weixing Zhao, Sivaraja Vaithiyalingam, Joseph San Filippo, David G. Maranon, Judit Jimenez-Sainz, Gerald V. Fontenay, Youngho Kwon, Stanley G. Leung, Lucy Lu, Ryan B. Jensen, Walter J. Chazin, Claudia Wiese & Patrick Sung. (2015) Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry. Molecular Cell 59:2, pages 176-187.
Crossref
Sembulingam Tamilzhalagan, Muthulakshmi Muthuswami, Jayaprakash Periasamy, Ming Hui Lee, Sun Young Rha, Patrick Tan & Kumaresan Ganesan. (2015) Upregulated, 7q21–22 amplicon candidate gene SHFM1 confers oncogenic advantage by suppressing p53 function in gastric cancer. Cellular Signalling 27:6, pages 1075-1086.
Crossref
Julie Lecarpentier, Catherine Noguès, Emmanuelle Mouret-Fourme, Bruno Buecher, Marion Gauthier-Villars, Dominique Stoppa-Lyonnet, Valérie Bonadona, Jean-Pierre Fricker, Pascaline Berthet, Olivier Caron, Isabelle Coupier, Pascal Pujol, Laurence Faivre, Paul Gesta, François Eisinger, Véronique Mari, Laurence Gladieff, Alain Lortholary, Elisabeth Luporsi, Dominique Leroux, Laurence Venat-Bouvet, Christine M. Maugard, Chrystelle Colas, Julie Tinat, Christine Lasset & Nadine Andrieu. (2015) Breast Cancer Risk Associated with Estrogen Exposure and Truncating Mutation Location in BRCA1/2 Carriers . Cancer Epidemiology, Biomarkers & Prevention 24:4, pages 698-707.
Crossref
Chantal Stoepker, Atiq Faramarz, Martin A. Rooimans, Saskia E. van Mil, Jesper A. Balk, Eunike Velleuer, Najim Ameziane, Hein te Riele & Johan P. de Winter. (2015) DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity. DNA Repair 26, pages 54-64.
Crossref
Jacqueline H. Barlow & André Nussenzweig. (2014) Replication initiation and genome instability: a crossroads for DNA and RNA synthesis. Cellular and Molecular Life Sciences 71:23, pages 4545-4559.
Crossref
Nicoletta Guaragnella, Ersilia Marra, Alvaro Galli, Loredana Moro & Sergio Giannattasio. (2014) Silencing of BRCA2 decreases anoikis and its heterologous expression sensitizes yeast cells to acetic acid-induced programmed cell death. Apoptosis 19:9, pages 1330-1341.
Crossref
Nicoletta Guaragnella, Vanessa Palermo, Alvaro Galli, Loredana Moro, Cristina Mazzoni & Sergio Giannattasio. (2014) The expanding role of yeast in cancer research and diagnosis: insights into the function of the oncosuppressors p53 and BRCA1/2. FEMS Yeast Research 14:1, pages 2-16.
Crossref
Robert J. TomkoJr.Jr. & Mark Hochstrasser. (2014) The Intrinsically Disordered Sem1 Protein Functions as a Molecular Tether during Proteasome Lid Biogenesis. Molecular Cell 53:3, pages 433-443.
Crossref
Cheng-Xin Gong. (2014) DSSylation, a novel guide for protein degradation?. Protein & Cell 5:2, pages 91-93.
Crossref
Yinghao Zhang, Fang-Mei Chang, Jianjun Huang, Jacob J. Junco, Shivani K. Maffi, Hannah I. Pridgen, Gabriel Catano, Hong Dang, Xiang Ding, Fuquan Yang, Dae Joon Kim, Thomas J. Slaga, Rongqiao He & Sung-Jen Wei. (2014) DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells. Protein & Cell 5:2, pages 124-140.
Crossref
Sandra Bonache, Sara Gutierrez-Enriquez, Anna Tenés, Miriam Masas, Judith Balmaña & Orland Diez. (2013) Mutation analysis of the BCCIP gene for breast cancer susceptibility in breast/ovarian cancer families. Gynecologic Oncology 131:2, pages 460-463.
Crossref
Anand D Jeyasekharan, Yang Liu, Hiroyoshi Hattori, Venkat Pisupati, Asta Bjork Jonsdottir, Eeson Rajendra, Miyoung Lee, Elayanambi Sundaramoorthy, Simon Schlachter, Clemens F Kaminski, Yaara Ofir-Rosenfeld, Ko Sato, Jane Savill, Nabieh Ayoub & Ashok R Venkitaraman. (2013) A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization. Nature Structural & Molecular Biology 20:10, pages 1191-1198.
Crossref
Vihandha O. Wickramasinghe, Jane M. Savill, Sreenivas Chavali, Asta B. Jonsdottir, Eeson Rajendra, Tamara Grüner, Ronald A. Laskey, M. Madan Babu & Ashok R. Venkitaraman. (2013) Human Inositol Polyphosphate Multikinase Regulates Transcript-Selective Nuclear mRNA Export to Preserve Genome Integrity. Molecular Cell 51:6, pages 737-750.
Crossref
Claire Concannon & Robert S. Lahue. (2013) The 26S proteasome drives trinucleotide repeat expansions. Nucleic Acids Research 41:12, pages 6098-6108.
Crossref
Stefan Bohn, Eri Sakata, Florian Beck, Ganesh R. Pathare, Jérôme Schnitger, Istvan Nágy, Wolfgang Baumeister & Friedrich Förster. (2013) Localization of the regulatory particle subunit Sem1 in the 26S proteasome. Biochemical and Biophysical Research Communications 435:2, pages 250-254.
Crossref
Jason D. Russell, Mark Scalf, Adam J. Book, Daniel T. Ladror, Richard D. Vierstra, Lloyd M. Smith & Joshua J. Coon. (2013) Characterization and Quantification of Intact 26S Proteasome Proteins by Real-Time Measurement of Intrinsic Fluorescence Prior to Top-down Mass Spectrometry. PLoS ONE 8:3, pages e58157.
Crossref
Sandra Bonache, Miguel de la Hoya, Sara Gutierrez-Enriquez, Anna Tenés, Miriam Masas, Judith Balmaña & Orland Diez. (2013) Mutation analysis of the SHFM1 gene in breast/ovarian cancer families. Journal of Cancer Research and Clinical Oncology 139:3, pages 529-532.
Crossref
Yen-Ying Ma, Hao Lin, Fang-Mei Chang, Ting-Chang Chang, Tiffany Trieu, Hannah I. Pridgen, Yinghao Zhang, Jianjun Huang, Karina Patiño-Guzman, Nabih Diab, Angelica Cantu, Thomas J. Slaga & Sung-Jen Wei. (2013) Identification of the deleted in split hand/split foot 1 protein as a novel biomarker for human cervical cancer. Carcinogenesis 34:1, pages 68-78.
Crossref
James S. Fraser, John D. Gross & Nevan J. Krogan. (2013) From Systems to Structure: Bridging Networks and Mechanism. Molecular Cell 49:2, pages 222-231.
Crossref
Larry H. Thompson. (2012) Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography. Mutation Research/Reviews in Mutation Research 751:2, pages 158-246.
Crossref
Paul Warrener, Sammy Kim, Sybil M. G. Williams, Matthew Biery, Marcia Gordon, Carlo Toniatti, Michele A. Cleary, Peter S. Linsley & Michael Carleton. (2012) Synthetic lethality of PARP inhibition in BRCA-network disrupted tumor cells is associated with interferon pathway activation and enhanced by interferon-γ. Apoptosis 17:7, pages 691-701.
Crossref
Avgi Tsolou, Glyn Nelson, Varvara Trachana, Niki Chondrogianni, Gabriele Saretzki, Thomas von Zglinicki & Efstathios S. Gonos. (2012) The 19S proteasome subunit Rpn7 stabilizes DNA damage foci upon genotoxic insult. IUBMB Life 64:5, pages 432-442.
Crossref
Rachel Brough, Ilirjana Bajrami, Radost Vatcheva, Rachael Natrajan, Jorge S Reis-Filho, Christopher J Lord & Alan Ashworth. (2012) APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer. The EMBO Journal 31:5, pages 1160-1176.
Crossref
Ravindra Amunugama & Richard Fishel. 2012. Mechanisms of DNA Repair. Mechanisms of DNA Repair 155 206 .
Nicolas Siaud, Maria A. Barbera, Akinori Egashira, Isabel Lam, Nicole Christ, Katharina Schlacher, Bing Xia & Maria Jasin. (2011) Plasticity of BRCA2 Function in Homologous Recombination: Genetic Interactions of the PALB2 and DNA Binding Domains. PLoS Genetics 7:12, pages e1002409.
Crossref
Julie Lecarpentier, Catherine Noguès, Emmanuelle Mouret-Fourme, Dominique Stoppa-Lyonnet, Christine Lasset, Olivier Caron, Jean-Pierre Fricker, Laurence Gladieff, Laurence Faivre, Hagay Sobol, Paul Gesta, Marc Frenay, Elisabeth Luporsi, Isabelle Coupier, Rosette Lidereau & Nadine Andrieu. (2011) Variation in breast cancer risk with mutation position, smoking, alcohol, and chest X-ray history, in the French National BRCA1/2 carrier cohort (GENEPSO). Breast Cancer Research and Treatment 130:3, pages 927-938.
Crossref
Santosh Kesari, Sunil J Advani, Joshua D Lawson, Kristopher T Kahle, Kimberly Ng, Bob Carter & Clark C Chen. (2011) DNA damage response and repair: insights into strategies for radiation sensitization of gliomas. Future Oncology 7:11, pages 1335-1346.
Crossref
William K Holloman. (2011) Unraveling the mechanism of BRCA2 in homologous recombination. Nature Structural & Molecular Biology 18:7, pages 748-754.
Crossref
Mack HallIIIIII, Smita Misra, Minu Chaudhuri & Gautam Chaudhuri. (2011) Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei. Microbial Pathogenesis 50:5, pages 252-262.
Crossref
K. Somyajit, S. Subramanya & G. Nagaraju. (2010) RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer. Carcinogenesis 31:12, pages 2031-2038.
Crossref
Jie Liu, Tammy Doty, Bryan Gibson & Wolf-Dietrich Heyer. (2010) Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA. Nature Structural & Molecular Biology 17:10, pages 1260-1262.
Crossref
Elizabeth M. Kass & Maria Jasin. (2010) Collaboration and competition between DNA double-strand break repair pathways. FEBS Letters 584:17, pages 3703-3708.
Crossref
Orland Diez, Sara Gutiérrez-Enríquez, Miriam Masas, Anna Tenés, Carme Yagüe, Angels Arcusa & Gemma Llort. (2010) Identification of a new complex deleterious mutation in exon 18 of the BRCA2 gene in a hereditary male/female breast cancer family. Breast Cancer Research and Treatment 123:2, pages 587-590.
Crossref
Lynn Bedford, Simon Paine, Paul W. Sheppard, R. John Mayer & Jeroen Roelofs. (2010) Assembly, structure, and function of the 26S proteasome. Trends in Cell Biology 20:7, pages 391-401.
Crossref
Meredith E. Jackrel, Aitziber L. Cortajarena, Tina Y. Liu & Lynne Regan. (2010) Screening Libraries To Identify Proteins with Desired Binding Activities Using a Split-GFP Reassembly Assay. ACS Chemical Biology 5:6, pages 553-562.
Crossref
Aitziber L. Cortajarena, Tina Y. Liu, Mark Hochstrasser & Lynne Regan. (2010) Designed Proteins To Modulate Cellular Networks. ACS Chemical Biology 5:6, pages 545-552.
Crossref
Mario Venza, Teresa Catalano, Maria Visalli, Isabella Venza, Maria Lentini, Maria Cristina Curia, Renato Mariani-Costantini & Diana Teti. (2010) Association of the DSS1 c.143G>A Polymorphism with Skin Squamous Cell Carcinoma. Journal of Investigative Dermatology 130:6, pages 1719-1725.
Crossref
Akira Motegi, Yasuhiro Murakawa & Shunichi Takeda. (2009) The vital link between the ubiquitin–proteasome pathway and DNA repair: Impact on cancer therapy. Cancer Letters 283:1, pages 1-9.
Crossref
Edward James, Maeve G. Waldron-Lynch & Muhammad Wasif Saif. (2009) Prolonged survival in a patient with BRCA2 associated metastatic pancreatic cancer after exposure to camptothecin: a case report and review of literature. Anti-Cancer Drugs 20:7, pages 634-638.
Crossref
Leontina Di Cecco, Erika Melissari, Veronica Mariotti, Caterina Iofrida, Alvaro Galli, Lucia Guidugli, Grazia Lombardi, Maria Adelaide Caligo, Paola Iacopetti & Silvia Pellegrini. (2009) Characterisation of gene expression profiles of yeast cells expressing BRCA1 missense variants. European Journal of Cancer 45:12, pages 2187-2196.
Crossref
Marius Boulos Faza, Stefan Kemmler, Sonia Jimeno, Cristina González-Aguilera, Andrés Aguilera, Ed Hurt & Vikram Govind Panse. (2009) Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery. Journal of Cell Biology 184:6, pages 833-846.
Crossref
Nir Yosef, Lior Ungar, Einat Zalckvar, Adi Kimchi, Martin Kupiec, Eytan Ruppin & Roded Sharan. (2009) Toward accurate reconstruction of functional protein networks. Molecular Systems Biology 5:1.
Crossref
Kienan Savage & D. Paul Harkin. 2009. The DNA Damage Response: Implications on Cancer Formation and Treatment. The DNA Damage Response: Implications on Cancer Formation and Treatment 415 443 .
Sylvie Mazoyer. 2010. The Role of Genetics in Breast and Reproductive Cancers. The Role of Genetics in Breast and Reproductive Cancers 93 105 .
Johanna Pispa, Susanna Palmén, Carina I Holmberg & Jussi Jäntti. (2008) C. elegans dss-1is functionally conserved and required for oogenesis and larval growth. BMC Developmental Biology 8:1.
Crossref
Sung-Jen Wei, Jason G. Williams, Hong Dang, Thomas A. Darden, Bryan L. Betz, Margaret M. Humble, Fang-Mei Chang, Carol S. Trempus, Katina Johnson, Ronald E. Cannon & Raymond W. Tennant. (2008) Identification of a Specific Motif of the DSS1 Protein Required for Proteasome Interaction and p53 Protein Degradation. Journal of Molecular Biology 383:3, pages 693-712.
Crossref
Joseph San FilippoPatrick SungHannah Klein. (2008) Mechanism of Eukaryotic Homologous Recombination. Annual Review of Biochemistry 77:1, pages 229-257.
Crossref
Justin Wray, Jingmei Liu, Jac A. Nickoloff & Zhiyuan Shen. (2008) Distinct RAD51 Associations with RAD52 and BCCIP in Response to DNA Damage and Replication Stress. Cancer Research 68:8, pages 2699-2707.
Crossref
Rachel KarchinMukesh AgarwalAndrej SaliFergus CouchMary S. Beattie. (2008) Classifying Variants of Undetermined Significance in BRCA2 with Protein Likelihood Ratios. Cancer Informatics 6, pages CIN.S618.
Crossref
Michael SY Huen & Junjie Chen. (2007) The DNA damage response pathways: at the crossroad of protein modifications. Cell Research 18:1, pages 8-16.
Crossref
Rachel Brough, Debbie Wei, Sophie Leulier, Christopher J. Lord, Yikang S. Rong & Alan Ashworth. (2008) Functional analysis of Drosophila melanogaster BRCA2 in DNA repair. DNA Repair 7:1, pages 10-19.
Crossref
Taro Mannen, Tomoko Andoh & Tokio Tani. (2008) Dss1 associating with the proteasome functions in selective nuclear mRNA export in yeast. Biochemical and Biophysical Research Communications 365:4, pages 664-671.
Crossref
K Gudmundsdottir, C J Lord & A Ashworth. (2007) The proteasome is involved in determining differential utilization of double-strand break repair pathways. Oncogene 26:54, pages 7601-7606.
Crossref
Justyna McIntyre, Hanna Baranowska, Adrianna Skoneczna, Agnieszka Halas & Ewa Sledziewska-Gojska. (2007) The spectrum of spontaneous mutations caused by deficiency in proteasome maturase Ump1 in Saccharomyces cerevisiae. Current Genetics 52:5-6, pages 221-228.
Crossref
Ninghui Mao, Qingwen Zhou, Milorad Kojic, José Pérez-Martín & William K. Holloman. (2007) Ortholog of BRCA2-interacting protein BCCIP controls morphogenetic responses during DNA replication stress in Ustilago maydis. DNA Repair 6:11, pages 1651-1660.
Crossref
Peter J. McKinnonKeith W. Caldecott. (2007) DNA Strand Break Repair and Human Genetic Disease. Annual Review of Genomics and Human Genetics 8:1, pages 37-55.
Crossref
Céline Jacquemont & Toshiyasu Taniguchi. (2007) Proteasome Function Is Required for DNA Damage Response and Fanconi Anemia Pathway Activation. Cancer Research 67:15, pages 7395-7405.
Crossref
Ganesh Nagaraju & Ralph Scully. (2007) Minding the gap: The underground functions of BRCA1 and BRCA2 at stalled replication forks. DNA Repair 6:7, pages 1018-1031.
Crossref
Tatiana Garcia-Muse & Simon J. Boulton. (2007) Meiotic recombination in Caenorhabditis elegans. Chromosome Research 15:5, pages 607-621.
Crossref
Kirsi Syrjäkoski, Jussi Jäntti, Anne Kallioniemi & Ritva Karhu. (2007) Mutations in the BRCA2 interacting DSS1 are not a risk factor for male breast cancer. International Journal of Cancer 120:2, pages 444-446.
Crossref
Nicole Christ, Mary Ellen Moynahan & Maria Jasin. 2007. Molecular Genetics of Recombination. Molecular Genetics of Recombination 363 380 .
S.J. Boulton. (2006) Cellular functions of the BRCA tumour-suppressor proteins. Biochemical Society Transactions 34:5, pages 633-645.
Crossref
Patrick Sung & Hannah Klein. (2006) Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nature Reviews Molecular Cell Biology 7:10, pages 739-750.
Crossref
K Gudmundsdottir & A Ashworth. (2006) The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. Oncogene 25:43, pages 5864-5874.
Crossref
Mark I.R. Petalcorin, Jane Sandall, Dale B. Wigley & Simon J. Boulton. (2006) CeBRC-2 Stimulates D-loop Formation by RAD-51 and Promotes DNA Single-strand Annealing. Journal of Molecular Biology 361:2, pages 231-242.
Crossref
Bing Xia, Qing Sheng, Koji Nakanishi, Akihiro Ohashi, Jianmin Wu, Nicole Christ, Xinggang Liu, Maria Jasin, Fergus J. Couch & David M. Livingston. (2006) Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2. Molecular Cell 22:6, pages 719-729.
Crossref
Joseph San Filippo, Peter Chi, Michael G. Sehorn, Julia Etchin, Lumir Krejci & Patrick Sung. (2006) Recombination Mediator and Rad51 Targeting Activities of a Human BRCA2 Polypeptide. Journal of Biological Chemistry 281:17, pages 11649-11657.
Crossref
Eloïse Dray, Nicolas Siaud, Emeline Dubois & Marie-Pascale Doutriaux. (2006) Interaction between Arabidopsis Brca2 and Its Partners Rad51, Dmc1, and Dss1. Plant Physiology 140:3, pages 1059-1069.
Crossref
J Li, C Zou, Y Bai, D E Wazer, V Band & Q Gao. (2005) DSS1 is required for the stability of BRCA2. Oncogene 25:8, pages 1186-1194.
Crossref
Lyne JosséMargaret E. HarleyIsabel M. S. PiresDavid A. Hughes. (2005) Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis. Biochemical Journal 393:1, pages 303-309.
Crossref
Adayabalam S. BalajeeKatrin Gudmundsdottir, Emily Witt & Alan Ashworth. 2006. DNA Repair and Human Disease. DNA Repair and Human Disease 47 60 .
Christopher D. Houle, Shyamal D. Peddada, Kimberly A. McAllister, Toni Ward, Jason Malphurs, William D. Gersch & Barbara J. Davis. (2005) Mutant Brca2/p53 mice exhibit altered radiation responses in the developing mammary gland. Experimental and Toxicologic Pathology 57:2, pages 105-115.
Crossref
David Baillat, Mohamed-Ali Hakimi, Anders M. Näär, Ali Shilatifard, Neil Cooch & Ramin Shiekhattar. (2005) Integrator, a Multiprotein Mediator of Small Nuclear RNA Processing, Associates with the C-Terminal Repeat of RNA Polymerase II. Cell 123:2, pages 265-276.
Crossref
Anjan G Thakurta, Ganesh Gopal, Jin Ho Yoon, Libor Kozak & Ravi Dhar. (2005) Homolog of BRCA2-interacting Dss1p and Uap56p link Mlo3p and Rae1p for mRNA export in fission yeast. The EMBO Journal 24:14, pages 2512-2523.
Crossref
YEHIAM SALTS, IRINA SOBOLEV, INNA CHMELNITSKY, SARA SHABTAI & RIVKA BARG. (2005) Genomic structure and expression of Lestd1, a seven-transmembrane-domain protein- encoding gene specifically expressed in tomato pollen. Israel Journal of Plant Sciences 53:2, pages 79-88.
Crossref
Xin-xia Tian, Deepak Rai, Jun Li, Chaozhong Zou, Yujie Bai, David Wazer, Vimla Band & Qingshen Gao. (2005) BRCA2 Suppresses Cell Proliferation via Stabilizing MAGE-D1. Cancer Research 65:11, pages 4747-4753.
Crossref
Patrick Sung. (2005) Mediating repair. Nature Structural & Molecular Biology 12:3, pages 213-214.
Crossref
Frederick J. Bowring, P. Jane Yeadon & David E.A. Catcheside. 2005. Genes and Genomics. Genes and Genomics 1 32 .
Minoru Funakoshi, Xia Li, Irina Velichutina, Mark Hochstrasser & Hideki Kobayashi. (2004) Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability. Journal of Cell Science 117:26, pages 6447-6454.
Crossref
Nevan J. Krogan, Mandy H.Y. Lam, Jeffrey Fillingham, Michael-Christopher Keogh, Marinella Gebbia, Joyce Li, Nira Datta, Gerard Cagney, Stephen Buratowski, Andrew Emili & Jack F. Greenblatt. (2004) Proteasome Involvement in the Repair of DNA Double-Strand Breaks. Molecular Cell 16:6, pages 1027-1034.
Crossref
. (2016) Aspen Cancer Conference Fellows. Toxicologic Pathology 32:6, pages 749-761.
Crossref
Katrin Gudmundsdottir, Christopher J Lord, Emily Witt, Andrew N J Tutt & Alan Ashworth. (2004) DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells. EMBO reports 5:10, pages 989-993.
Crossref
Mahmud K.K. Shivji & Ashok R. Venkitaraman. (2004) DNA recombination, chromosomal stability and carcinogenesis: insights into the role of BRCA2. DNA Repair 3:8-9, pages 835-843.
Crossref
Takayuki Sone, Yasushi Saeki, Akio Toh-e & Hideyoshi Yokosawa. (2004) Sem1p Is a Novel Subunit of the 26 S Proteasome from Saccharomyces cerevisiae. Journal of Biological Chemistry 279:27, pages 28807-28816.
Crossref
Sung-Jen Wei, Carol S. Trempus, Robin C. Ali, Laura A. Hansen & Raymond W. Tennant. (2004) 12-O-Tetradecanoylphorbol-13-acetate and UV Radiation-induced Nucleoside Diphosphate Protein Kinase B Mediates Neoplastic Transformation of Epidermal Cells. Journal of Biological Chemistry 279:7, pages 5993-6004.
Crossref
Nan Hu, Chaoyu Wang, Xiao-You Han, Li-Ji He, Ze-Zhong Tang, Carol Giffen, Michael R Emmert-Buck, Alisa M Goldstein & Philip R Taylor. (2003) Evaluation of BRCA2 in the genetic susceptibility of familial esophageal cancer. Oncogene 23:3, pages 852-858.
Crossref
Milorad Kojic, Haijuan Yang, Corwin F. Kostrub, Nikola P. Pavletich & William K. Holloman. (2003) The BRCA2-Interacting Protein DSS1 Is Vital for DNA Repair, Recombination, and Genome Stability in Ustilago maydis. Molecular Cell 12:4, pages 1043-1049.
Crossref
Horng-Ru Lin, Nicholas S.Y. Ting, Jun Qin & Wen-Hwa Lee. (2003) M Phase-specific Phosphorylation of BRCA2 by Polo-like Kinase 1 Correlates with the Dissociation of the BRCA2-P/CAF Complex. Journal of Biological Chemistry 278:38, pages 35979-35987.
Crossref
Thomas Lo, Luca Pellegrini, Ashok R. Venkitaraman & Tom L. Blundell. (2003) Sequence fingerprints in BRCA2 and RAD51: implications for DNA repair and cancer. DNA Repair 2:9, pages 1015-1028.
Crossref
Mirka Reinman, Jussi Jäntti, Kaija Alfthan, Sirkka Keränen, Hans Söderlund & Kristiina Takkinen. (2003) Functional inactivation of the conserved Sem1p in yeast by intrabodies. Yeast 20:12, pages 1071-1084.
Crossref
Stephen C. West. (2003) Molecular views of recombination proteins and their control. Nature Reviews Molecular Cell Biology 4:6, pages 435-445.
Crossref
Greg Donoho, Mark A. Brenneman, Tracy X. Cui, Dorit Donoviel, Hannes Vogel, Edwin H. Goodwin, David J. Chen & Paul Hasty. (2003) Deletion ofBrca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice. Genes, Chromosomes and Cancer 36:4, pages 317-331.
Crossref
Simona Agata, Arcangela De Nicolo, Luigi Chieco-Bianchi, Emma D'Andrea, Chiara Menin & Marco Montagna. (2003) The BRCA2 sequence variant IVS19+1G→A leads to an aberrant transcript lacking exon 19. Cancer Genetics and Cytogenetics 141:2, pages 175-176.
Crossref
Sung-Jen Wei, Carol S. Trempus, Ronald E. Cannon, Carl D. Bortner & Raymond W. Tennant. (2003) Identification of Dss1 as a 12-O-Tetradecanoylphorbol-13-acetate-responsive Gene Expressed in Keratinocyte Progenitor Cells, with Possible Involvement in Early Skin Tumorigenesis. Journal of Biological Chemistry 278:3, pages 1758-1768.
Crossref
Maria Jasin. (2002) Homologous repair of DNA damage and tumorigenesis:the BRCA connection. Oncogene 21:58, pages 8981-8993.
Crossref
H Vidarsson, E.K Mikaelsdottir, T Rafnar, D Bertwistle, A Ashworth, J.E Eyfjord & S Valgeirsdottir. (2002) BRCA1 and BRCA2 bind Stat5a and suppress its transcriptional activity. FEBS Letters 532:1-2, pages 247-252.
Crossref
Andrew Tutt & Alan Ashworth. (2002) The relationship between the roles of BRCA genes in DNA repair and cancer predisposition. Trends in Molecular Medicine 8:12, pages 571-576.
Crossref
Larry H Thompson & David Schild. (2002) Recombinational DNA repair and human disease. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 509:1-2, pages 49-78.
Crossref
Haijuan YangPhilip D. Jeffrey, Julie MillerElspeth Kinnucan, Yutong SunNicolas H. Thomä, Ning ZhengPhang-Lang ChenWen-Hwa LeeNikola P. Pavletich. (2002) BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure. Science 297:5588, pages 1837-1848.
Crossref
Minoru Takata, Seiji Tachiiri, Akira Fujimori, Larry H Thompson, Yoshio Miki, Masahiro Hiraoka, Shunichi Takeda & Mitsuyoshi Yamazoe. (2002) Conserved domains in the chicken homologue of BRCA2. Oncogene 21:7, pages 1130-1134.
Crossref
Ingrid A. Hedenfalk, Markus Ringnér, Jeffrey M. Trent & Ake Borg. 2002. 1 34 .
Yuan Yuan & Zhiyuan Shen. (2001) Interaction with BRCA2 Suggests a Role for Filamin-1 (hsFLNa) in DNA Damage Response. Journal of Biological Chemistry 276:51, pages 48318-48324.
Crossref
Åke Borg. (2001) Molecular and pathological characterization of inherited breast cancer. Seminars in Cancer Biology 11:5, pages 375-385.
Crossref
Lei Zheng, Shang Li, Thomas G Boyer & Wen-Hwa Lee. (2000) Lessons learned from BRCA1 and BRCA2. Oncogene 19:53, pages 6159-6175.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.