Citations (55)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Jakub M. Swiercz, Thomas Worzfeld & Stefan Offermanns. (2009) Semaphorin 4D Signaling Requires the Recruitment of Phospholipase Cγ into the Plexin-B1 Receptor Complex. Molecular and Cellular Biology 29:23, pages 6321-6334.
Read now
Read now
Neil P. Jones & Matilda Katan. (2007) Role of Phospholipase Cγ1 in Cell Spreading Requires Association with a β-Pix/GIT1-Containing Complex, Leading to Activation of Cdc42 and Rac1. Molecular and Cellular Biology 27:16, pages 5790-5805.
Read now
Read now
Karen DeBell, Laurie Graham, Ilona Reischl, Carmen Serrano, Ezio Bonvini & Barbara Rellahan. (2007) Intramolecular Regulation of Phospholipase C-γ1 by Its C-Terminal Src Homology 2 Domain. Molecular and Cellular Biology 27:3, pages 854-863.
Read now
Read now
Brenda J. Irvin, Brandi L. Williams, Allan E. Nilson, Hannah O. Maynor & Robert T. Abraham. (2000) Pleiotropic Contributions of Phospholipase C-γ1 (PLC-γ1) to T-Cell Antigen Receptor-Mediated Signaling: Reconstitution Studies of a PLC-γ1-Deficient Jurkat T-Cell Line. Molecular and Cellular Biology 20:24, pages 9149-9161.
Read now
Read now
Karen E. DeBell, Bogdan A. Stoica, Maria-Concetta Verí, Angela Di Baldassarre, Sebastiano Miscia, Laurie J. Graham, Barbara L. Rellahan, Masamichi Ishiai, Tomohiro Kurosaki & Ezio Bonvini. (1999) Functional Independence and Interdependence of the Src Homology Domains of Phospholipase C-γ1 in B-Cell Receptor Signal Transduction. Molecular and Cellular Biology 19:11, pages 7388-7398.
Read now
Read now
Articles from other publishers (50)
Edhriz Siraliev-Perez, Jordan TB Stariha, Reece M Hoffmann, Brenda RS Temple, Qisheng Zhang, Nicole Hajicek, Meredith L Jenkins, John E Burke & John Sondek. (2022) Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes. eLife 11.
Crossref
Crossref
Beatriz C. Moraes, Helder V. Ribeiro-Filho, Allan P. Roldão, Elaine F. Toniolo, Gustavo P. B. Carretero, Germán G. Sgro, Fernanda A. H. Batista, Damian E. Berardi, Victoria R. S. Oliveira, Rebeka TomasinFelipe M. Vieceli, Dimitrius T. Pramio, Alexandre B. Cardoso, Ana C. M. Figueira, Shaker C. Farah, Lakshmi A. Devi, Camila S. Dale, Paulo S. L. de Oliveira & Deborah Schechtman. (2022) Structural analysis of TrkA mutations in patients with congenital insensitivity to pain reveals PLCγ as an analgesic drug target. Science Signaling 15:731.
Crossref
Crossref
Dongying Chen & Michael Simons. (2021) Emerging roles of PLCγ1 in endothelial biology. Science Signaling 14:694.
Crossref
Crossref
Naira Samarina, George Ssebyatika, Tanvi Tikla, Ja-Yun Waldmann, Bizunesh Abere, Vittoria Nanna, Michelangelo Marasco, Teresa Carlomagno, Thomas Krey & Thomas F. Schulz. (2021) Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation. PLOS Pathogens 17:6, pages e1009635.
Crossref
Crossref
Timothy Travers, William K. Kanagy, Rachael A. Mansbach, Elton Jhamba, Cedric Cleyrat, Byron Goldstein, Diane S. Lidke, Bridget S. Wilson & S. Gnanakaran. (2019) Combinatorial diversity of Syk recruitment driven by its multivalent engagement with FcεRIγ. Molecular Biology of the Cell 30:17, pages 2331-2347.
Crossref
Crossref
Karthik Tiruthani, Adam Mischler, Shoeb Ahmed, Jessica Mahinthakumar, Jason M. Haugh & Balaji M. Rao. (2019) Design and evaluation of engineered protein biosensors for live-cell imaging of EGFR phosphorylation. Science Signaling 12:584.
Crossref
Crossref
Marissa A. McKercher, Xiaoyang Guan, Zhongping Tan & Deborah S. Wuttke. (2017) Multimodal Recognition of Diverse Peptides by the C-Terminal SH2 Domain of Phospholipase C-γ1 Protein. Biochemistry 56:16, pages 2225-2237.
Crossref
Crossref
Tom D. Bunney & Matilda Katan. (2011) PLC regulation: emerging pictures for molecular mechanisms. Trends in Biochemical Sciences 36:2, pages 88-96.
Crossref
Crossref
John E. Ladbury & Stefan T. Arold. 2011. Biothermodynamics, Part C. Biothermodynamics, Part C
147
183
.
Gregor Neumayr, Tibor Rudas & Othmar Steinhauser. (2010) Global and local Voronoi analysis of solvation shells of proteins. The Journal of Chemical Physics 133:8, pages 084108.
Crossref
Crossref
Cornelia E. Crooke, Ambra Pozzi & Graham F. Carpenter. (2009) PLC-γ1 regulates fibronectin assembly and cell aggregation. Experimental Cell Research 315:13, pages 2207-2214.
Crossref
Crossref
Susanne Müller & Stefan Knapp. (2009) Out of the Box Binding Determines Specificity of SH2 Domain Interaction. Structure 17:8, pages 1040-1041.
Crossref
Crossref
Jae Hyun Bae, Erin Denise Lew, Satoru Yuzawa, Francisco Tomé, Irit Lax & Joseph Schlessinger. (2009) The Selectivity of Receptor Tyrosine Kinase Signaling Is Controlled by a Secondary SH2 Domain Binding Site. Cell 138:3, pages 514-524.
Crossref
Crossref
L.D. Covassin, A.F. Siekmann, M.C. Kacergis, E. Laver, J.C. Moore, J.A. Villefranc, B.M. Weinstein & N.D. Lawson. (2009) A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development. Developmental Biology 329:2, pages 212-226.
Crossref
Crossref
H. Yagisawa. 2009. Handbook of Neurochemistry and Molecular Neurobiology. Handbook of Neurochemistry and Molecular Neurobiology
269
296
.
Washa Liu, Katja Zscheppang, Sandy Murray, Heber C. Nielsen & Christiane E.L. Dammann. (2007) The ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cells. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1772:7, pages 737-747.
Crossref
Crossref
Yaohong Wang, Alok Tomar, Sudeep P. George & Seema Khurana. (2007)
Obligatory role for phospholipase C-γ
1
in villin-induced epithelial cell migration
. American Journal of Physiology-Cell Physiology 292:5, pages C1775-C1786.
Crossref
Crossref
T. Rudas, C. Schröder, S. Boresch & O. Steinhauser. (2006) Simulation studies of the protein-water interface. II. Properties at the mesoscopic resolution. The Journal of Chemical Physics 124:23.
Crossref
Crossref
C. Schröder, T. Rudas, S. Boresch & O. Steinhauser. (2006) Simulation studies of the protein-water interface. I. Properties at the molecular resolution. The Journal of Chemical Physics 124:23.
Crossref
Crossref
Hong-Jun Liao, Josué de los Santos & Graham Carpenter. (2006) Contrasting role of phospholipase C-γ1 in the expression of immediate early genes induced by epidermal or platelet-derived growth factors. Experimental Cell Research 312:6, pages 807-816.
Crossref
Crossref
Helena Frecker, Snezana Munk, Hong Wang & Catharine Whiteside. (2005)
Mesangial cell-reduced Ca
2+
signaling in high glucose is due to inactivation of phospholipase C-β
3
by protein kinase C
. American Journal of Physiology-Renal Physiology 289:5, pages F1078-F1087.
Crossref
Crossref
Lu Deng, C. Alejandro Velikovsky, Chittoor P. Swaminathan, Sangwoo Cho & Roy A. Mariuzza. (2005) Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cγ1. Journal of Molecular Biology 352:1, pages 1-10.
Crossref
Crossref
Simone Radtke, Serge Haan, Angela Jörissen, Heike M. Hermanns, Sandra Diefenbach, Tanya Smyczek, Hildegard Schmitz-VandeLeur, Peter C. Heinrich, Iris Behrmann & Claude Haan. (2005) The Jak1 SH2 Domain Does Not Fulfill a Classical SH2 Function in Jak/STATSignaling but Plays a Structural Role for Receptor Interaction andUp-regulation of Receptor SurfaceExpression. Journal of Biological Chemistry 280:27, pages 25760-25768.
Crossref
Crossref
Xia Liu & Keqiang Ye. (2005) Src homology domains in phospholipase C-gamma1 mediate its anti-apoptotic action through regulating the enzymatic activity. Journal of Neurochemistry 93:4, pages 892-898.
Crossref
Crossref
Benoit Poulin, Fujio Sekiya & Sue Goo Rhee. (2005) Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-γ1. Proceedings of the National Academy of Sciences 102:12, pages 4276-4281.
Crossref
Crossref
Denis Tvorogov, Xue-Jie Wang, Roy Zent & Graham Carpenter. (2005) Integrin-dependent PLC-γ1 phosphorylation mediates fibronectin-dependent adhesion. Journal of Cell Science 118:3, pages 601-610.
Crossref
Crossref
Fujio Sekiya, Benoit Poulin, Yeun Ju Kim & Sue Goo Rhee. (2004) Mechanism of Tyrosine Phosphorylation and Activation of Phospholipase C-γ1. Journal of Biological Chemistry 279:31, pages 32181-32190.
Crossref
Crossref
Michel Bernier, Hua-Jun He, Yong-Kook Kwon & Hyeung-Jin Jang. 2004.
221
247
.
Yong-Kook Kwon, Hyeung-Jin Jang, Sutapa Kole, Hua-Jun He & Michel Bernier. (2003) Role of the pleckstrin homology domain of PLCγ1 in its interaction with the insulin receptor. Journal of Cell Biology 163:2, pages 375-384.
Crossref
Crossref
Tetsuya Yamamoto, Taro Yumioka, Yuichi Sekine, Noriko Sato, Mayu Minoguchi, Akihiko Yoshimura & Tadashi Matsuda. (2003) Regulation of FcεRI-mediated signaling by an adaptor protein STAP-2/BSK in rat basophilic leukemia RBL-2H3 cells. Biochemical and Biophysical Research Communications 306:3, pages 767-773.
Crossref
Crossref
Jay Jie Liu, Deborah S Hartman & James Robert Bostwick. (2003) An immobilized metal ion affinity adsorption and scintillation proximity assay for receptor-stimulated phosphoinositide hydrolysis. Analytical Biochemistry 318:1, pages 91-99.
Crossref
Crossref
Ezio Bonvini, Karen E DeBell, Maria-Concetta Verı́, Laurie Graham, Bogdan Stoica, Jorge Laborda, M.Javad Aman, Angela DiBaldassarre, Sebastiano Miscia & Barbara L Rellahan. (2003) On the mechanism coupling phospholipase Cγ1 to the B- and T-cell antigen receptors. Advances in Enzyme Regulation 43:1, pages 245-269.
Crossref
Crossref
Rosana D. Meyer, Catharina Latz & Nader Rahimi. (2003) Recruitment and Activation of Phospholipase Cγ1 by Vascular Endothelial Growth Factor Receptor-2 Are Required for Tubulogenesis and Differentiation of Endothelial Cells. Journal of Biological Chemistry 278:18, pages 16347-16355.
Crossref
Crossref
Martina Schmidt, Paschal A Oude Weernink, Frank vom Dorp, Matthias B Stope & Karl H Jakobs. 2003. Lipobiology. Lipobiology
431
450
.
Suhas A. Kotecha & John F. MacDonald. 2003.
51
106
.
Denis Tvorogov & Graham Carpenter. (2002) EGF-Dependent Association of Phospholipase C-γ1 with c-Cbl. Experimental Cell Research 277:1, pages 86-94.
Crossref
Crossref
Ansuman Chattopadhyay & Graham Carpenter. (2002) PLC-γ1 is required for IGF-I protection from cell death induced by loss of extracellular matrix adhesion. Journal of Cell Science 115:10, pages 2233-2239.
Crossref
Crossref
Jens Eichhorn, Ayse G. Kayali, Laura Resor, Darrell A. Austin, David W. Rose & Nicholas J. G. Webster. (2002) PLC-γ1 Enzyme Activity Is Required for Insulin-Induced DNA Synthesis. Endocrinology 143:2, pages 655-664.
Crossref
Crossref
Jonathan I Wilde & Steve P Watson. (2001) Regulation of phospholipase C γ isoforms in haematopoietic cells. Cellular Signalling 13:10, pages 691-701.
Crossref
Crossref
Xian-Tao Wang, Karen D. McCullough, Xue-Jie Wang, Graham Carpenter & Nikki J. Holbrook. (2001) Oxidative Stress-induced Phospholipase C-γ1 Activation Enhances Cell Survival. Journal of Biological Chemistry 276:30, pages 28364-28371.
Crossref
Crossref
Xue-Jie Wang, Hong-Jun Liao, Ansuman Chattopadhyay & Graham Carpenter. (2001) EGF-Dependent Translocation of Green Fluorescent Protein-Tagged PLC-γ1 to the Plasma Membrane and Endosomes. Experimental Cell Research 267:1, pages 28-36.
Crossref
Crossref
Sue Goo Rhee. (2001) Regulation of Phosphoinositide-Specific Phospholipase C. Annual Review of Biochemistry 70:1, pages 281-312.
Crossref
Crossref
Miho Matsuda, Hugh F. Paterson, Rosie Rodriguez, Amanda C. Fensome, Moira V. Ellis, Karl Swann & Matilda Katan. (2001) Real Time Fluorescence Imaging of Plcγ Translocation and Its Interaction with the Epidermal Growth Factor Receptor. Journal of Cell Biology 153:3, pages 599-612.
Crossref
Crossref
Hong-Jun Liao, Qun-Sheng Ji & Graham Carpenter. (2001) Phospholipase C-γ1 Is Required for the Induction of Immediate Early Genes by Platelet-derived Growth Factor. Journal of Biological Chemistry 276:12, pages 8627-8630.
Crossref
Crossref
Rebecca L. Rich & David G. Myszka. (2000) Survey of the 1999 surface plasmon resonance biosensor literature. Journal of Molecular Recognition 13:6, pages 388-407.
Crossref
Crossref
W.H. Kinsey & S.S. Shen. (2000) Role of the Fyn Kinase in Calcium Release during Fertilization of the Sea Urchin Egg. Developmental Biology 225:1, pages 253-264.
Crossref
Crossref
Qun-sheng Ji & Graham Carpenter. (2000) Role of basal calcium in the EGF activation of MAP kinases. Oncogene 19:14, pages 1853-1856.
Crossref
Crossref
Benoit Poulin, Fujio Sekiya & Sue Goo Rhee. (2000) Differential Roles of the Src Homology 2 Domains of Phospholipase C-γ1 (PLC-γ1) in Platelet-derived Growth Factor-induced Activation of PLC-γ1 in Intact Cells. Journal of Biological Chemistry 275:9, pages 6411-6416.
Crossref
Crossref
Shiou-Ru Tzeng, Ming-Tao Pai, Chih-Wei Wu, Jya-Wei Cheng, Feng-Di T. Lung, Peter P. Roller, Benfang Lei, Chih-Jen Wei, Shiao-Chun Tu, Shi-Han Chen & Wen-Jue Soong. (2000) Stability and peptide binding specificity of Btk SH2 domain: Molecular basis for X-linked agammaglobulinemia. Protein Science 9:12, pages 2377-2385.
Crossref
Crossref
Graham Carpenter & Qun-sheng Ji. (1999) Phospholipase C-γ as a Signal-Transducing Element. Experimental Cell Research 253:1, pages 15-24.
Crossref
Crossref