Citations (61)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (7)
Sharon Soucek, Yi Zeng, Deepti L. Bellur, Megan Bergkessel, Kevin J. Morris, Qiudong Deng, Duc Duong, Nicholas T. Seyfried, Christine Guthrie, Jonathan P. Staley, Milo B. Fasken & Anita H. Corbett. (2016) Evolutionarily Conserved Polyadenosine RNA Binding Protein Nab2 Cooperates with Splicing Machinery To Regulate the Fate of Pre-mRNA. Molecular and Cellular Biology 36:21, pages 2697-2714.
Read now
Read now
Maliheh Movassat, Tara L. Crabb, Anke Busch, Chengguo Yao, Derrick J. Reynolds, Yongsheng Shi & Klemens J. Hertel. (2016) Coupling between alternative polyadenylation and alternative splicing is limited to terminal introns. RNA Biology 13:7, pages 646-655.
Read now
Read now
Frank Rigo & Harold G. Martinson. (2008) Functional Coupling of Last-Intron Splicing and 3′-End Processing to Transcription In Vitro: the Poly(A) Signal Couples to Splicing before Committing to Cleavage. Molecular and Cellular Biology 28:2, pages 849-862.
Read now
Read now
Chunxiao Wu & James C. Alwine. (2004) Secondary Structure as a Functional Feature in the Downstream Region of Mammalian Polyadenylation Signals. Molecular and Cellular Biology 24:7, pages 2789-2796.
Read now
Read now
Charles Cooke & James C. Alwine. (2002) Characterization of Specific Protein-RNA Complexes Associated with the Coupling of Polyadenylation and Last-Intron Removal. Molecular and Cellular Biology 22:13, pages 4579-4586.
Read now
Read now
S. A. Beckley, P. Liu, M. L. Stover, S. I. Gunderson, A. C. Lichtler & D. W. Rowe. (2001) Reduction of Target Gene Expression by a Modified U1 snRNA. Molecular and Cellular Biology 21:8, pages 2815-2825.
Read now
Read now
Holly Hans & James C. Alwine. (2000) Functionally Significant Secondary Structure of the Simian Virus 40 Late Polyadenylation Signal. Molecular and Cellular Biology 20:8, pages 2926-2932.
Read now
Read now
Articles from other publishers (54)
Michael Tellier, Justyna Zaborowska, Jonathan Neve, Takayuki Nojima, Svenja Hester, Marjorie Fournier, Andre Furger & Shona Murphy. (2022)
CDK9
and
PP2A
regulate
RNA
polymerase
II
transcription termination and coupled
RNA
maturation
. EMBO reports 23:10.
Crossref
Crossref
Elena Sánchez-Escabias, José A. Guerrero-Martínez & José C. Reyes. (2022) Co-transcriptional splicing efficiency is a gene-specific feature that can be regulated by TGFβ. Communications Biology 5:1.
Crossref
Crossref
Jun Cao, Sunil K. Verma, Elizabeth Jaworski, Stephanie Mohan, Chloe K. Nagasawa, Kempaiah Rayavara, Amanda Sooter, Sierra N. Miller, Richard J. Holcomb, Mason J. Powell, Ping Ji, Nathan D. Elrod, Eda Yildirim, Eric J. Wagner, Vsevolod Popov, Nisha J. Garg, Andrew L. Routh & Muge N. Kuyumcu-Martinez. (2021) RBFOX2 is critical for maintaining alternative polyadenylation patterns and mitochondrial health in rat myoblasts. Cell Reports 37:5, pages 109910.
Crossref
Crossref
Seyed-Fakhreddin Torabi, Suzanne J. DeGregorio & Joan A. Steitz. (2021) tRNA-like leader-trailer interaction promotes 3′-end maturation of MALAT1. RNA 27:10, pages 1140-1147.
Crossref
Crossref
Yekaterina V. Makeyeva, Masaki Shirayama & Craig C. Mello. (2021) Cues from mRNA splicing prevent default Argonaute silencing in C. elegans. Developmental Cell 56:18, pages 2636-2648.e4.
Crossref
Crossref
Kirsten A. Reimer, Claudia A. Mimoso, Karen Adelman & Karla M. Neugebauer. (2021) Co-transcriptional splicing regulates 3′ end cleavage during mammalian erythropoiesis. Molecular Cell 81:5, pages 998-1012.e7.
Crossref
Crossref
Tara Alpert, Korinna Straube, Fernando Carrillo Oesterreich, Lydia Herzel & Karla M. Neugebauer. (2020) Widespread Transcriptional Readthrough Caused by Nab2 Depletion Leads to Chimeric Transcripts with Retained Introns. Cell Reports 33:4, pages 108324.
Crossref
Crossref
Michael Tellier, Isabella Maudlin & Shona Murphy. (2020) Transcription and splicing: A two‐way street. WIREs RNA 11:5.
Crossref
Crossref
Seyed Yahya Anvar, Guy Allard, Elizabeth Tseng, Gloria M. Sheynkman, Eleonora de Klerk, Martijn Vermaat, Raymund H. Yin, Hans E. Johansson, Yavuz Ariyurek, Johan T. den Dunnen, Stephen W. Turner & Peter A. C. ‘t Hoen. (2018) Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing. Genome Biology 19:1.
Crossref
Crossref
Lydia Herzel, Diana S. M. Ottoz, Tara Alpert & Karla M. Neugebauer. (2017) Splicing and transcription touch base: co-transcriptional spliceosome assembly and function. Nature Reviews Molecular Cell Biology 18:10, pages 637-650.
Crossref
Crossref
Daisuke Kaida. (2016) The reciprocal regulation between splicing and 3′‐end processing. WIREs RNA 7:4, pages 499-511.
Crossref
Crossref
Olufemi O. Fasina, Yanming Dong & David J. Pintel. (2016) NP1 Protein of the Bocaparvovirus Minute Virus of Canines Controls Access to the Viral Capsid Genes via Its Role in RNA Processing. Journal of Virology 90:4, pages 1718-1728.
Crossref
Crossref
Daniel P. Morris, Beilei Lei, Lawrence D. Longo, Karol Bomsztyk, Debra A. Schwinn & Gregory A. Michelotti. (2015) Temporal Dissection of Rate Limiting Transcriptional Events Using Pol II ChIP and RNA Analysis of Adrenergic Stress Gene Activation. PLOS ONE 10:8, pages e0134442.
Crossref
Crossref
Francesco Catania & Michael Lynch. (2013) A simple model to explain evolutionary trends of eukaryotic gene architecture and expression. BioEssays 35:6, pages 561-570.
Crossref
Crossref
Kamel Jabbari. 2001. eLS. eLS.
Irina Evsyukova, Shelton S. Bradrick, Simon G. Gregory & Mariano A. Garcia-Blanco. (2013) Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6. RNA 19:1, pages 103-115.
Crossref
Crossref
Yevgenia L. Khodor, Jerome S. Menet, Michael Tolan & Michael Rosbash. (2012)
Cotranscriptional splicing efficiency differs dramatically between
Drosophila
and mouse
. RNA 18:12, pages 2174-2186.
Crossref
Crossref
Kristine Potter, Nicole Cremona, Sham Sunder & Jo Ann Wise. (2012) A dominant role for meiosis-specific 3′ RNA processing in controlling expression of a fission yeast cyclin gene. RNA 18:7, pages 1408-1420.
Crossref
Crossref
Brian P. Cusack, Peter F. Arndt, Laurent Duret & Hugues Roest Crollius. (2011) Preventing Dangerous Nonsense: Selection for Robustness to Transcriptional Error in Human Genes. PLoS Genetics 7:10, pages e1002276.
Crossref
Crossref
Amy Pandya‐Jones. (2011) Pre‐mRNA splicing during transcription in the mammalian system. WIREs RNA 2:5, pages 700-717.
Crossref
Crossref
Harold G. Martinson. (2011) An active role for splicing in 3′-end formation. Wiley Interdisciplinary Reviews: RNA 2:4, pages 459-470.
Crossref
Crossref
Alexander E. Smith, Constantinos Chronis, Manolis Christodoulakis, Stephen J. Orr, Nicholas C. Lea, Natalie A. Twine, Akshay Bhinge, Ghulam J. Mufti & N. Shaun B. Thomas. (2009)
Epigenetics of human T cells during the G
0
→G
1
transition
. Genome Research 19:8, pages 1325-1337.
Crossref
Crossref
David S McPheeters, Nicole Cremona, Sham Sunder, Huei-Mei Chen, Nicole Averbeck, Janet Leatherwood & Jo Ann Wise. (2009) A complex gene regulatory mechanism that operates at the nexus of multiple RNA processing decisions. Nature Structural & Molecular Biology 16:3, pages 255-264.
Crossref
Crossref
Kamel Jabbari & Edda Rayko. 2001. eLS. eLS.
Jenny Blechingberg, Søren Lykke-Andersen, Torben Heick Jensen, Arne Lund Jørgensen & Anders Lade Nielsen. (2007) Regulatory mechanisms for 3′-end alternative splicing and polyadenylation of the Glial Fibrillary Acidic Protein, GFAP, transcript. Nucleic Acids Research 35:22, pages 7636-7650.
Crossref
Crossref
Martin C. Frith, Piero Carninci, Chikatoshi Kai, Jun Kawai, Timothy L. Bailey, Yoshihide Hayashizaki & John S. Mattick. (2007) Splicing bypasses 3′ end formation signals to allow complex gene architectures. Gene 403:1-2, pages 188-193.
Crossref
Crossref
Nicole L. Maciolek & Mark T. McNally. (2007) Serine/Arginine-Rich Proteins Contribute to Negative Regulator of Splicing Element-Stimulated Polyadenylation in Rous Sarcoma Virus. Journal of Virology 81:20, pages 11208-11217.
Crossref
Crossref
Scott A. Akker, Shivani Misra, Shazad Aslam, Emma L. Morgan, Philip J. Smith, Bernard Khoo & Shern L. Chew. (2007) Pre-Spliceosomal Binding of U1 Small Nuclear Ribonucleoprotein (RNP) and Heterogenous Nuclear RNP E1 Is Associated with Suppression of a Growth Hormone Receptor Pseudoexon. Molecular Endocrinology 21:10, pages 2529-2540.
Crossref
Crossref
Jianming Qiu, Fang Cheng & David Pintel. (2007) Distance-Dependent Processing of Adeno-Associated Virus Type 5 RNA Is Controlled by 5′ Exon Definition. Journal of Virology 81:15, pages 7974-7984.
Crossref
Crossref
Bin Tian, Zhenhua Pan & Ju Youn Lee. (2007) Widespread mRNA polyadenylation events in introns indicate dynamic interplay between polyadenylation and splicing. Genome Research 17:2, pages 156-165.
Crossref
Crossref
Hui Zhu, Hua-Lin Zhou, Robert A. Hasman & Hua Lou. (2007) Hu Proteins Regulate Polyadenylation by Blocking Sites Containing U-rich Sequences. Journal of Biological Chemistry 282:4, pages 2203-2210.
Crossref
Crossref
Lawrence A. Chasin. 2007. Alternative Splicing in the Postgenomic Era. Alternative Splicing in the Postgenomic Era
85
106
.
N Ivanova, A Löfgren, I Tournev, R Rousev, A Andreeva, A Jordanova, V Georgieva, T Deconinck, V Timmerman, I Kremensky, P De Jonghe & V Mitev. (2006) Spastin gene mutations in Bulgarian patients with hereditary spastic paraplegia. Clinical Genetics 70:6, pages 490-495.
Crossref
Crossref
Stefania Millevoi, Clarisse Loulergue, Sabine Dettwiler, Sarah Zeïneb Karaa, Walter Keller, Michael Antoniou & Stéphan Vagner. (2006) An interaction between U2AF 65 and CF Im links the splicing and 3′ end processing machineries. The EMBO Journal 25:20, pages 4854-4864.
Crossref
Crossref
Andrea Kyburz, Arno Friedlein, Hanno Langen & Walter Keller. (2006) Direct Interactions between Subunits of CPSF and the U2 snRNP Contribute to the Coupling of Pre-mRNA 3′ End Processing and Splicing. Molecular Cell 23:2, pages 195-205.
Crossref
Crossref
Serkan A. AlkanKathleen MartincicChristine Milcarek. (2005) The hnRNPs F and H2 bind to similar sequences to influence gene expression. Biochemical Journal 393:1, pages 361-371.
Crossref
Crossref
Frank Rigo, Amir Kazerouninia, Anita Nag & Harold G. Martinson. (2005) The RNA Tether from the Poly(A) Signal to the Polymerase Mediates Coupling of Transcription to Cleavage and Polyadenylation. Molecular Cell 20:5, pages 733-745.
Crossref
Crossref
Margaret Rush, Xiaomin Zhao & Stefan Schwartz. (2005) A Splicing Enhancer in the E4 Coding Region of Human Papillomavirus Type 16 Is Required for Early mRNA Splicing and Polyadenylation as Well as Inhibition of Premature Late Gene Expression. Journal of Virology 79:18, pages 12002-12015.
Crossref
Crossref
A Carson, Z Wang, X Xiao & S A Khan. (2005) A DNA recombination-based approach to eliminate papillomavirus infection. Gene Therapy 12:6, pages 534-540.
Crossref
Crossref
Nadine Puget, Melodie Knowlton & Ralph Scully. (2005) Molecular analysis of sister chromatid recombination in mammalian cells. DNA Repair 4:2, pages 149-161.
Crossref
Crossref
Sita Awasthi, Jennifer A. Isler & James C. Alwine. (2004) Analysis of Splice Variants of the Immediate-Early 1 Region of Human Cytomegalovirus. Journal of Virology 78:15, pages 8191-8200.
Crossref
Crossref
T. Rauch & Ibolya Kiss. (2003) How to find the real one. Acta Biologica Hungarica 54:3-4, pages 219-231.
Crossref
Crossref
SITA AWASTHI & JAMES C. ALWINE. (2003) Association of polyadenylation cleavage factor I with U1 snRNP. RNA 9:11, pages 1400-1409.
Crossref
Crossref
Véronique Noé, Simon MacKenzie & Carlos J. Ciudad. (2003) An Intron Is Required for Dihydrofolate Reductase Protein Stability. Journal of Biological Chemistry 278:40, pages 38292-38300.
Crossref
Crossref
C M Stover, N J Lynch, M R Dahl, S Hanson, M Takahashi, M Frankenberger, L Ziegler-Heitbrock, I Eperon, S Thiel & W J Schwaeble. (2003) Murine serine proteases MASP-1 and MASP-3, components of the lectin pathway activation complex of complement, are encoded by a single structural gene. Genes & Immunity 4:5, pages 374-384.
Crossref
Crossref
Mariacristina Chioda, Ragnhild Eskeland & Eric M. Thompson. (2002) Histone Gene Complement, Variant Expression, and mRNA Processing in a Urochordate Oikopleura dioica that Undergoes Extensive Polyploidization. Molecular Biology and Evolution 19:12, pages 2247-2260.
Crossref
Crossref
Christopher T. O'Sullivan, Tatjana S. Polony, Robert E. Paca & Karen L. Beemon. (2002) Rous Sarcoma Virus Negative Regulator of Splicing Selectively Suppresses src mRNA Splicing and Promotes Polyadenylation. Virology 302:2, pages 405-412.
Crossref
Crossref
Stefania Millevoi, Finola Geraghty, Bernadine Idowu, Jennifer L Y Tam, Michael Antoniou & Stéphan Vagner. (2002) A novel function for the U2AF 65 splicing factor in promoting pre‐mRNA 3′‐end processing. EMBO reports 3:9, pages 869-874.
Crossref
Crossref
Kenneth James Howe. (2002) RNA polymerase II conducts a symphony of pre-mRNA processing activities. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1577:2, pages 308-324.
Crossref
Crossref
L.M. Houdebine, J. Attal & J.L. Vilotte. 2002. Transgenic Animal Technology. Transgenic Animal Technology
419
458
.
M. I. Zarudnaya. (2001) mRNA polyadenylation. 1. 3'-end formation of vertebrates' mRNAs. Biopolymers and Cell 17:2, pages 93-108.
Crossref
Crossref
Magnus Molin & Göran Akusjärvi. (2000) Overexpression of Essential Splicing Factor ASF/SF2 Blocks the Temporal Shift in Adenovirus Pre-mRNA Splicing and Reduces Virus Progeny Formation. Journal of Virology 74:19, pages 9002-9009.
Crossref
Crossref
Kimberly S. Ellison, Stephen A. Rice, Robert Verity & James R. Smiley. (2000) Processing of α-Globin and ICP0 mRNA in Cells Infected with Herpes Simplex Virus Type 1 ICP27 Mutants. Journal of Virology 74:16, pages 7307-7319.
Crossref
Crossref
Peter Cheung, Kimberly S. Ellison, Robert Verity & James R. Smiley. (2000) Herpes Simplex Virus ICP27 Induces Cytoplasmic Accumulation of Unspliced Polyadenylated α-Globin Pre-mRNA in Infected HeLa Cells. Journal of Virology 74:6, pages 2913-2919.
Crossref
Crossref