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Molecular and Cellular Biology Volume 20, 2000 - Issue 15
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DNA Dynamics and Chromosome Structure

Stimulation of Mitotic Recombination Events by High Levels of RNA Polymerase II Transcription in Yeast

Dean Saxe1 Graduate Program in Genetics and Molecular Biology
,
Abhijit Datta2 Graduate Program in Biochemistry and Molecular Biology
&
Sue Jinks-Robertson1 Graduate Program in Genetics and Molecular Biology;2 Graduate Program in Biochemistry and Molecular Biology;3 Department of Biology, Emory University, Atlanta, Georgia30322Correspondence[email protected]
Pages 5404-5414 | Received 28 Feb 2000, Accepted 09 May 2000, Published online: 28 Mar 2023

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Ezra Schildkraut, Cheryl A. Miller & Jac A. Nickoloff. (2006) Transcription of a Donor Enhances Its Use during Double-Strand Break-Induced Gene Conversion in Human Cells. Molecular and Cellular Biology 26:8, pages 3098-3105.
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Sevinc Ercan, Joseph C. Reese, Jerry L. Workman & Robert T. Simpson. (2005) Yeast Recombination Enhancer Is Stimulated by Transcription Activation. Molecular and Cellular Biology 25:18, pages 7976-7987.
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Malcolm J. Lippert, Jennifer A. Freedman, Melissa A. Barber & Sue Jinks-Robertson. (2004) Identification of a Distinctive Mutation Spectrum Associated with High Levels of Transcription in Yeast. Molecular and Cellular Biology 24:11, pages 4801-4809.
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Sebastián Chávez, Marı́a Garcı́a-Rubio, Félix Prado & Andrés Aguilera. (2001) Hpr1 Is Preferentially Required for Transcription of Either Long or G+C-Rich DNA Sequences in Saccharomyces cerevisiae. Molecular and Cellular Biology 21:20, pages 7054-7064.
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Hobert Wai, Katsuki Johzuka, Loan Vu, Kristilyn Eliason, Takehiko Kobayashi, Takashi Horiuchi & Masayasu Nomura. (2001) Yeast RNA Polymerase I Enhancer Is Dispensable for Transcription of the Chromosomal rRNA Gene and Cell Growth, and Its Apparent Transcription Enhancement from Ectopic Promoters Requires Fob1 Protein. Molecular and Cellular Biology 21:16, pages 5541-5553.
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Articles from other publishers (30)

Ryo Sakasai, Mayu Isono, Mitsuo Wakasugi, Mitsumasa Hashimoto, Yumi Sunatani, Tadashi Matsui, Atsushi Shibata, Tsukasa Matsunaga & Kuniyoshi Iwabuchi. (2017) Aquarius is required for proper CtIP expression and homologous recombination repair. Scientific Reports 7:1.
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Walter W. Steiner, Chelsea L. Recor & Bethany M. Zakrzewski. (2016) Unique properties of multiple tandem copies of the M26 recombination hotspot in mitosis and meiosis in Schizosaccharomyces pombe. Gene 593:1, pages 185-192.
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Puja Yadav, Norah Owiti & Nayun Kim. (2016) The role of topoisomerase I in suppressing genome instability associated with a highly transcribed guanine-rich sequence is not restricted to preventing RNA:DNA hybrid accumulation. Nucleic Acids Research 44:2, pages 718-729.
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Lorraine S Symington, Rodney Rothstein & Michael Lisby. (2014) Mechanisms and Regulation of Mitotic Recombination in Saccharomyces cerevisiae . Genetics 198:3, pages 795-835.
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Hélène Gaillard, Emilia Herrera-Moyano & Andrés Aguilera. (2013) Transcription-Associated Genome Instability. Chemical Reviews 113:11, pages 8638-8661.
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Nayun Kim & Sue Jinks-Robertson. (2012) Transcription as a source of genome instability. Nature Reviews Genetics 13:3, pages 204-214.
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Lamia Wahba, Jeremy D. Amon, Douglas Koshland & Milena Vuica-Ross. (2011) RNase H and Multiple RNA Biogenesis Factors Cooperate to Prevent RNA:DNA Hybrids from Generating Genome Instability. Molecular Cell 44:6, pages 978-988.
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José F. Ruiz, Belén Gómez-González & Andrés Aguilera. (2011) AID Induces Double-Strand Breaks at Immunoglobulin Switch Regions and c-MYC Causing Chromosomal Translocations in Yeast THO Mutants. PLoS Genetics 7:2, pages e1002009.
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Belén Gómez-González, José F. Ruiz & Andrés Aguilera. 2011. DNA Recombination. DNA Recombination 151 172 .
Ozan Aygün & Jesper Q. Svejstrup. (2010) RECQL5 helicase: Connections to DNA recombination and RNA polymerase II transcription. DNA Repair 9:3, pages 345-353.
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P. Gottipati & T. Helleday. (2009) Transcription-associated recombination in eukaryotes: link between transcription, replication and recombination. Mutagenesis 24:3, pages 203-210.
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Michelle Hanna, Lindsay G. Ball, Amy H. Tong, Charles Boone & Wei Xiao. (2007) Pol32 is required for Polζ-dependent translesion synthesis and prevents double-strand breaks at the replication fork. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 625:1-2, pages 164-176.
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Peter J. I. van de Vondervoort, Sandra M. J. Langeveld, Jaap Visser, Noël N. M. E. van Peij, Herman J. Pel, Cees A. M. J. J. van den Hondel & Arthur F. J. Ram. (2007) Identification of a mitotic recombination hotspot on chromosome III of the asexual fungus Aspergillus niger and its possible correlation elevated basal transcription. Current Genetics 52:3-4, pages 107-114.
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Marcin Filipecki & Stefan Malepszy. (2006) Unintended consequences of plant transformation: A molecular insight. Journal of Applied Genetics 47:4, pages 277-286.
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Errol C. Friedberg, Graham C. Walker, Wolfram Siede, Richard D. Wood, Roger A. Schultz & Tom Ellenberger. 2005. DNA Repair and Mutagenesis. DNA Repair and Mutagenesis 663 710 .
Saumyadipta Pyne, Steven Skiena & Bruce Futcher. (2005) Copy Correction and Concerted Evolution in the Conservation of Yeast Genes. Genetics 170:4, pages 1501-1513.
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Laura L. Sharkey, Wei-li Liao, Anup K. Ghosh & William A. Fonzi. (2005) Flanking direct repeats of hisG alter URA3 marker expression at the HWP1 locus of Candida albicans. Microbiology 151:4, pages 1061-1071.
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Félix Prado & Andrés Aguilera. (2005) Impairment of replication fork progression mediates RNA polII transcription-associated recombination. The EMBO Journal 24:6, pages 1267-1276.
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Jennifer A. Freedman & Sue Jinks-Robertson. (2004) Effects of mismatch repair and Hpr1 on transcription-stimulated mitotic recombination in the yeast Saccharomyces cerevisiae. DNA Repair 3:11, pages 1437-1446.
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Lance D. Langston & Lorraine S. Symington. (2004) Gene targeting in yeast is initiated by two independent strand invasions. Proceedings of the National Academy of Sciences 101:43, pages 15392-15397.
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K. Gjuracic, E. Pivetta & C. V. Bruschi. (2004) Targeted DNA integration within different functional gene domains in yeast reveals ORF sequences as recombinational cold-spots. Molecular Genetics and Genomics 271:4, pages 437-446.
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Nikolas Nikolaidis & Masatoshi Nei. (2004) Concerted and Nonconcerted Evolution of the Hsp70 Gene Superfamily in Two Sibling Species of Nematodes. Molecular Biology and Evolution 21:3, pages 498-505.
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M García-Rubio, P Huertas, S González-Barrera & A Aguilera. (2003) Recombinogenic Effects of DNA-Damaging Agents Are Synergistically Increased by Transcription in Saccharomyces cerevisiae : New Insights Into Transcription-Associated Recombination . Genetics 165:2, pages 457-466.
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Yasushi Takeuchi, Takashi Horiuchi & Takehiko Kobayashi. (2003) Transcription-dependent recombination and the role of fork collision in yeast rDNA. Genes & Development 17:12, pages 1497-1506.
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Sergio González-Barrera, María García-Rubio & Andrés Aguilera. (2002) Transcription and Double-Strand Breaks Induce Similar Mitotic Recombination Events in Saccharomyces cerevisiae . Genetics 162:2, pages 603-614.
Crossref
Jennifer A Freedman & Sue Jinks-Robertson. (2002) Genetic Requirements for Spontaneous and Transcription-Stimulated Mitotic Recombination in Saccharomyces cerevisiae . Genetics 162:1, pages 15-27.
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Jan M. Lucht, Brigitte Mauch-Mani, Henry-York Steiner, Jean-Pierre Metraux, John Ryals & Barbara Hohn. (2002) Pathogen stress increases somatic recombination frequency in Arabidopsis. Nature Genetics 30:3, pages 311-314.
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Andrés Aguilera. (2002) The connection between transcription and genomic instability. The EMBO Journal 21:3, pages 195-201.
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Francisco Malagón & Andrés Aguilera. (2001) Yeast spt6-140 Mutation, Affecting Chromatin and Transcription, Preferentially Increases Recombination in Which Rad51p-Mediated Strand Exchange Is Dispensable . Genetics 158:2, pages 597-611.
Crossref
. (2000) Current Awareness. Yeast 16:15, pages 1449-1456.
Crossref

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