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Molecular and Cellular Biology Volume 20, 2000 - Issue 17
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DNA Dynamics and Chromosome Structure

Functional Studies on the Candidate ATPase Domains of Saccharomyces cerevisiae MutLα

Phuoc T. TranDepartment of Molecular and Medical Genetics, Oregon Health Sciences University, Portland, Oregon97201
&
R. Michael LiskayDepartment of Molecular and Medical Genetics, Oregon Health Sciences University, Portland, Oregon97201Correspondence[email protected]
Pages 6390-6398 | Received 21 Mar 2000, Accepted 07 Jun 2000, Published online: 28 Mar 2023

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Nicholas J. Brideau, Heather Coker, Anne-Valerie Gendrel, C. Alistair Siebert, Karel Bezstarosti, Jeroen Demmers, Raymond A. Poot, Tatyana B. Nesterova & Neil Brockdorff. (2015) Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome. Molecular and Cellular Biology 35:23, pages 4053-4068.
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Claudine Dherin, Emeric Gueneau, Mathilde Francin, Marcela Nunez, Simona Miron, Sascha Emilie Liberti, Lene Juel Rasmussen, Sophie Zinn-Justin, Bernard Gilquin, Jean-Baptiste Charbonnier & Serge Boiteux. (2009) Characterization of a Highly Conserved Binding Site of Mlh1 Required for Exonuclease I-Dependent Mismatch Repair. Molecular and Cellular Biology 29:3, pages 907-918.
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Naz Erdeniz, Sandra Dudley, Regan Gealy, Sue Jinks-Robertson & R. Michael Liskay. (2005) Novel PMS1 Alleles Preferentially Affect the Repair of Primer Strand Loops during DNA Replication. Molecular and Cellular Biology 25:21, pages 9221-9231.
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Xiaosheng Wu, Jeffrey L. Platt & Marilia Cascalho. (2003) Dimerization of MLH1 and PMS2 Limits Nuclear Localization of MutLα. Molecular and Cellular Biology 23:9, pages 3320-3328.
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Juan Lucas Argueso, Amanda Wraith Kijas, Sumeet Sarin, Julie Heck, Marc Waase & Eric Alani. (2003) Systematic Mutagenesis of the Saccharomyces cerevisiae MLH1 Gene Reveals Distinct Roles for Mlh1p in Meiotic Crossing Over and in Vegetative and Meiotic Mismatch Repair. Molecular and Cellular Biology 23:3, pages 873-886.
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Neelam S. Amin, My-Nga Nguyen, Scott Oh & Richard D. Kolodner. (2001) exo1-Dependent Mutator Mutations: Model System for Studying Functional Interactions in Mismatch Repair. Molecular and Cellular Biology 21:15, pages 5142-5155.
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Christopher M Furman, Ting-Yi Wang, Qiuye Zhao, Kumar Yugandhar, Haiyuan Yu & Eric Alani. (2021) Handcuffing intrinsically disordered regions in Mlh1–Pms1 disrupts mismatch repair. Nucleic Acids Research 49:16, pages 9327-9341.
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Gianno Pannafino & Eric Alani. (2021) Coordinated and Independent Roles for MLH Subunits in DNA Repair. Cells 10:4, pages 948.
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Kira C. BradfordHunter WilkinsPengyu HaoZimeng M. Li, Bangchen Wang, Dan BurkeDong WuAustin E. SmithLogan SpallerChunwei DuJacob W. GauerEdward ChanPeggy HsiehKeith R. WeningerDorothy A. Erie. (2020) Dynamic human MutSα–MutLα complexes compact mismatched DNA. Proceedings of the National Academy of Sciences 117:28, pages 16302-16312.
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Kazuo Tamura. 2020. Lynch Syndrome. Lynch Syndrome 1 20 .
Kazuo Tamura, Motohide Kaneda, Mashu Futagawa, Miho Takeshita, Sanghyuk Kim, Mina Nakama, Norihito Kawashita & Junko Tatsumi-Miyajima. (2019) Genetic and genomic basis of the mismatch repair system involved in Lynch syndrome. International Journal of Clinical Oncology 24:9, pages 999-1011.
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Yoori Kim, Christopher M Furman, Carol M Manhart, Eric Alani & Ilya J Finkelstein. (2018) Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex. Nucleic Acids Research.
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Corentin Claeys Bouuaert & Scott Keeney. (2017) Distinct DNA-binding surfaces in the ATPase and linker domains of MutLγ determine its substrate specificities and exert separable functions in meiotic recombination and mismatch repair. PLOS Genetics 13:5, pages e1006722.
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Andrew H. Lee & David A. Fidock. (2016) Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites. PLOS ONE 11:4, pages e0154166.
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Lyudmila Y. Kadyrova & Farid A. Kadyrov. (2016) Endonuclease activities of MutLα and its homologs in DNA mismatch repair. DNA Repair 38, pages 42-49.
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Monica C. Pillon, Vignesh M. P. Babu, Justin R. Randall, Jiudou Cai, Lyle A. Simmons, Mark D. Sutton & Alba Guarné. (2015) The sliding clamp tethers the endonuclease domain of MutL to DNA. Nucleic Acids Research 43:22, pages 10746-10759.
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Catherine E. Smith, Nikki Bowen, William J. GrahamVV, Eva M. Goellner, Anjana Srivatsan & Richard D. Kolodner. (2015) Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System. Journal of Biological Chemistry 290:35, pages 21580-21590.
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Michał Banasik & Paweł Sachadyn. (2014) Conserved motifs of MutL proteins. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 769, pages 69-79.
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Monica C. Pillon, Michelle Dubinsky, Randal N. Johnston, Shu-Lin Liu & Alba Guarné. (2013) Characterization of the defects in the ATP lid of E. coli MutL that cause transient hypermutability. DNA Repair 12:10, pages 864-869.
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