Advanced search
Publication Cover
Molecular and Cellular Biology Volume 20, 2000 - Issue 23
Submit an article Journal homepage
21
Views
82
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Repression of c-myc Is Necessary but Not Sufficient for Terminal Differentiation of B Lymphocytes In Vitro

Kuo-I Lin1 Department of Microbiology
,
Yi Lin1 Department of Microbiology
&
Kathryn Calame1 Department of Microbiology;2 Department of Biochemistry & Molecular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York10032Correspondence[email protected]
Pages 8684-8695 | Received 25 May 2000, Accepted 04 Sep 2000, Published online: 28 Mar 2023

Citations (82)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Annalisa D’Avola, Katarina Kluckova, Andrew J Finch & John C Riches. (2023) Spotlight on New Therapeutic Opportunities for MYC-Driven Cancers. OncoTargets and Therapy 16, pages 371-383.
Read now
Marc A. J. Morgan, Arne W. Mould, Li Li, Elizabeth J. Robertson & Elizabeth K. Bikoff. (2012) Alternative Splicing Regulates Prdm1/Blimp-1 DNA Binding Activities and Corepressor Interactions. Molecular and Cellular Biology 32:17, pages 3403-3413.
Read now
Kuo-I Lin, Cristina Angelin-Duclos, Tracy C. Kuo & Kathryn Calame. (2002) Blimp-1-Dependent Repression of Pax-5 Is Required for Differentiation of B Cells to Immunoglobulin M-Secreting Plasma Cells. Molecular and Cellular Biology 22:13, pages 4771-4780.
Read now

Articles from other publishers (79)

Anna Bajnok, Timea Serény-Litvai, Viktória Temesfői, Jasper Nörenberg, Róbert Herczeg, Ambrus Kaposi, Timea Berki & Emese Mezosi. (2023) An Optimized Flow Cytometric Method to Demonstrate the Differentiation Stage-Dependent Ca2+ Flux Responses of Peripheral Human B Cells. International Journal of Molecular Sciences 24:10, pages 9107.
Crossref
Casper Marsman, Niels JM Verstegen, Marij Streutker, Tineke Jorritsma, Louis Boon, Anja ten Brinke & S. Marieke van Ham. (2022) Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells. European Journal of Immunology 52:10, pages 1662-1675.
Crossref
Joel Finney & Garnett Kelsoe. (2021) Continuous Culture of Mouse Primary B Lymphocytes by Forced Expression of Bach2 . The Journal of Immunology 207:5, pages 1478-1492.
Crossref
Doan C. Nguyen, Meixue Duan, Mohammad Ali, Ariel Ley, Ignacio Sanz & F. Eun‐Hyung Lee. (2021) Plasma cell survival: The intrinsic drivers, migratory signals, and extrinsic regulators. Immunological Reviews 303:1, pages 138-153.
Crossref
So Hee Kim, Bokyung Kim, Jung Hak Kim, Dong-Hoon Kim, Seung Hoon Lee, Dong-Seok Lee & Hong J. Lee. (2021) L-myc Gene Expression in Canine Fetal Fibroblasts Promotes Self-Renewal Capacity but Not Tumor Formation. Cells 10:8, pages 1980.
Crossref
Qing Han, Rui Han, Xueli Lai, Jiule Wang, Yingtong Hu, Xiaochun Luo, Anxing Li, Zequan Mo, Yanwei Li & Xueming Dan. (2021) Sequence characteristics and expression profiles of Pax-5 and Blimp-1 in Epinephelus coioides following parasite infection and bacterial vaccination. Aquaculture Reports 20, pages 100725.
Crossref
Tyler J. RippergerDeepta Bhattacharya. (2021) Transcriptional and Metabolic Control of Memory B Cells and Plasma Cells. Annual Review of Immunology 39:1, pages 345-368.
Crossref
B. Zhai, C. Hou, R. Xu, Y. Fang, N. Ma, C. Xing, X. Wang, H. Xiao, G. Chen, G. Han & R. Wang. (2020) Gm6377 suppressed SP 2/0 xenograft tumor by down-regulating Myc transcription. Clinical and Translational Oncology 22:9, pages 1463-1471.
Crossref
Amol Tandon, Jana Birkenhagen, Deepthi Nagalla, Stefan Kölker & Sven Wolfgang Sauer. (2020) ADP-dependent glucokinase as a novel onco-target for haematological malignancies. Scientific Reports 10:1.
Crossref
Rui Guo, Chang Jiang, Yuchen Zhang, Apurva Govande, Stephen J. Trudeau, Fang Chen, Christopher J. Fry, Rishi Puri, Emma Wolinsky, Molly Schineller, Thomas C. Frost, Makda Gebre, Bo Zhao, Lisa Giulino-Roth, John G. Doench, Mingxiang Teng & Benjamin E. Gewurz. (2020) MYC Controls the Epstein-Barr Virus Lytic Switch. Molecular Cell 78:4, pages 653-669.e8.
Crossref
Wolfgang Schuh, Dirk Mielenz & Hans-Martin Jäck. 2020. 57 107 .
Xue Wang, Gui-liang Hao, Bo-ya Wang, Chen-chen Gao, Yue-xiu Wang, Li-sheng Li & Jing-dong Xu. (2019) Function and dysfunction of plasma cells in intestine. Cell & Bioscience 9:1.
Crossref
Simon N Willis & Stephen L Nutt. (2019) New players in the gene regulatory network controlling late B cell differentiation. Current Opinion in Immunology 58, pages 68-74.
Crossref
Koushik Roy, Simon Mitchell, Yi Liu, Sho Ohta, Yu-sheng Lin, Marie Oliver Metzig, Stephen L. Nutt & Alexander Hoffmann. (2019) A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation. Immunity 50:3, pages 616-628.e6.
Crossref
Francis O. Enane, Yogen Saunthararajah & Murray Korc. (2018) Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells. Cell Death & Disease 9:9.
Crossref
Alessandro Agnarelli, Tim Chevassut & Erika J. Mancini. (2018) IRF4 in multiple myeloma—Biology, disease and therapeutic target. Leukemia Research 72, pages 52-58.
Crossref
Natalie A. Roberts, Brian D. Adams, Nicholas I. McCarthy, Reuben M. Tooze, Sonia M. Parnell, Graham Anderson, Susan M. Kaech & Valerie Horsley. (2017) Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity. The Journal of Immunology 199:4, pages 1250-1260.
Crossref
Yuan Xiao Zhu, Chang-Xin Shi, Laura A. Bruins, Patrick Jedlowski, Xuewei Wang, K. Martin Kortüm, Moulun Luo, Jonathan M. Ahmann, Esteban Braggio & A. Keith Stewart. (2017) Loss of FAM46C Promotes Cell Survival in Myeloma . Cancer Research 77:16, pages 4317-4327.
Crossref
Yijie Ma, Michael J. Walsh, Katharina Bernhardt, Camille W. Ashbaugh, Stephen J. Trudeau, Isabelle Y. Ashbaugh, Sizun Jiang, Chang Jiang, Bo Zhao, David E. Root, John G. Doench & Benjamin E. Gewurz. (2017) CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors. Cell Host & Microbe 21:5, pages 580-591.e7.
Crossref
Inge Wolf, Corinne Bouquet, Friederike Naumann & Fritz Melchers. (2017) Generation of precursor, immature, and mature murine B1-cell lines from c-myc/bcl-xL-overexpressing pre-BI cells. European Journal of Immunology 47:5, pages 911-920.
Crossref
Olga Zaytseva & Leonie Quinn. (2017) Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling. Genes 8:4, pages 118.
Crossref
Van Trung ChuRobin GrafTristan WirtzTimm WeberJeremy FavretXun LiKerstin PetschNgoc Tung TranMichael H. SiewekeClaudia BerekRalf Kühn & Klaus Rajewsky. (2016) Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line. Proceedings of the National Academy of Sciences 113:44, pages 12514-12519.
Crossref
Y.-H. Yu & K.-I. Lin. 2016. 61 99 .
Stephen L. Nutt, Philip D. Hodgkin, David M. Tarlinton & Lynn M. Corcoran. (2015) The generation of antibody-secreting plasma cells. Nature Reviews Immunology 15:3, pages 160-171.
Crossref
Mona K. Saadeldin, Heba Shawer, Ahmed Mostafa, Neemat M. Kassem, Asma Amleh & Rania Siam. (2015) New genetic variants of LATS1 detected in urinary bladder and colon cancer. Frontiers in Genetics 5.
Crossref
Ghada Mohamed, Katerina Vrzalikova, Fathima Zumla Cader, Martina Vockerodt, Eszter Nagy, Patrik Flodr, Lee-Fah Yap, Arjan Diepstra, Philip M. Kluin, Stefano Rosati & Paul Murray. (2014) Epstein–Barr virus, the germinal centre and the development of Hodgkin’s lymphoma. Journal of General Virology 95:9, pages 1861-1869.
Crossref
Peng Dong, Manoj V. Maddali, Jaydeep K. Srimani, François Thélot, Joseph R. Nevins, Bernard Mathey-Prevot & Lingchong You. (2014) Division of labour between Myc and G1 cyclins in cell cycle commitment and pace control. Nature Communications 5:1.
Crossref
David Fernández, Maitane Ortiz, Lorena Rodríguez, Arancha García, Dolores Martinez & Ignacio Moreno de Alborán. (2013) The Proto-Oncogene c- myc Regulates Antibody Secretion and Ig Class Switch Recombination . The Journal of Immunology 190:12, pages 6135-6144.
Crossref
Katerina Vrzalikova, Ciaran Bernard John Woodman & Paul Gerard Murray. (2012) BLIMP1α, the master regulator of plasma cell differentiation is a tumor supressor gene in B cell lymphomas. Biomedical Papers 156:1, pages 1-6.
Crossref
Lars Fischer, Michael Hummel, Agnieszka Korfel, Dido Lenze, Korrina Joehrens & Eckhard Thiel. (2011) Differential micro-RNA expression in primary CNS and nodal diffuse large B-cell lymphomas. Neuro-Oncology 13:10, pages 1090-1098.
Crossref
Stephen L. Nutt, Nadine Taubenheim, Jhagvaral Hasbold, Lynn M. Corcoran & Philip D. Hodgkin. (2011) The genetic network controlling plasma cell differentiation. Seminars in Immunology 23:5, pages 341-349.
Crossref
Katerina VrzalikovaMartina VockerodtSarah LeonardAndrew BellWenbin WeiAlexandra Schrader, Kenneth L. Wright, Dieter Kube, Martin RoweCiaran B. WoodmanPaul G. Murray. (2011) Down-regulation of BLIMP1α by the EBV oncogene, LMP-1, disrupts the plasma cell differentiation program and prevents viral replication in B cells: implications for the pathogenesis of EBV-associated B-cell lymphomas. Blood 117:22, pages 5907-5917.
Crossref
T S Lewis, R S McCormick, I J Stone, K Emmerton, B Mbow, J Miyamoto, J G Drachman, I S Grewal & C-L Law. (2011) Proapoptotic signaling activity of the anti-CD40 monoclonal antibody dacetuzumab circumvents multiple oncogenic transformation events and chemosensitizes NHL cells. Leukemia 25:6, pages 1007-1016.
Crossref
Kimiko Katoh, Yoshihiro Omori, Akishi Onishi, Shigeru Sato, Mineo Kondo & Takahisa Furukawa. (2010) Blimp1 Suppresses Chx10 Expression in Differentiating Retinal Photoreceptor Precursors to Ensure Proper Photoreceptor Development . The Journal of Neuroscience 30:19, pages 6515-6526.
Crossref
Chunyang Lien, Chee-Mun Fang, David HusoFerenc Livak, Runqing Lu & Paula M. Pitha. (2010) Critical role of IRF-5 in regulation of B-cell differentiation. Proceedings of the National Academy of Sciences 107:10, pages 4664-4668.
Crossref
Shane Crotty, Robert J Johnston & Stephen P Schoenberger. (2010) Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nature Immunology 11:2, pages 114-120.
Crossref
Denise A. Birkholz, Eugenia C. Olesnicky Killian, Kathleen M. George & Kristin Bruk Artinger. (2009) Prdm1a is necessary for posterior pharyngeal arch development in zebrafish . Developmental Dynamics 238:10, pages 2575-2587.
Crossref
Shinu A. John & Lee Ann Garrett-Sinha. (2009) Blimp1: A conserved transcriptional repressor critical for differentiation of many tissues. Experimental Cell Research 315:7, pages 1077-1084.
Crossref
Chih-Ming Tsai, Yi-Kai Chiu, Tsui-Ling Hsu, I-Ying Lin, Shie-Liang Hsieh & Kuo-I Lin. (2008) Galectin-1 Promotes Immunoglobulin Production during Plasma Cell Differentiation. The Journal of Immunology 181:7, pages 4570-4579.
Crossref
Gislâine MartinsKathryn Calame. (2008) Regulation and Functions of Blimp-1 in T and B Lymphocytes. Annual Review of Immunology 26:1, pages 133-169.
Crossref
Stephen L. Nutt, Axel Kallies & Gabrielle T. Belz. (2007) Blimp-1 Connects the Intrinsic and Extrinsic Regulation of T Cell Homeostasis. Journal of Clinical Immunology 28:2, pages 97-106.
Crossref
Inken Wierstra & Jürgen Alves. 2008. 113 333 .
Fan-Ru Lin, Hui-Kai Kuo, Hsia-Yuan Ying, Fu-Hung Yang & Kuo-I Lin. (2007) Induction of Apoptosis in Plasma Cells by B Lymphocyte–Induced Maturation Protein-1 Knockdown. Cancer Research 67:24, pages 11914-11923.
Crossref
Xia Zhou, Hua Jiang & Jian Hou. (2007) Coordination of upregulated XBP-1 and downregulated c-myc during myeloma cell differentiation induced by 2-methoxyestradiol. Leukemia Research 31:9, pages 1259-1265.
Crossref
Axel Kallies & Stephen L Nutt. (2007) Terminal differentiation of lymphocytes depends on Blimp-1. Current Opinion in Immunology 19:2, pages 156-162.
Crossref
Dapeng Gong & Thomas R. Malek. (2007) Cytokine-Dependent Blimp-1 Expression in Activated T Cells Inhibits IL-2 Production. The Journal of Immunology 178:1, pages 242-252.
Crossref
Natalie Strudwick & Martin Schröder. 2007. Systems Biology. Systems Biology 69 155 .
David Savitsky, Luisa Cimmino, Tracy Kuo, Gislâine A. Martins & Kathryn Calame. 2007. Mechanisms of Lymphocyte Activation and Immune Regulation XI. Mechanisms of Lymphocyte Activation and Immune Regulation XI 9 30 .
Danijela Konforte & Christopher J. Paige. (2006) Identification of Cellular Intermediates and Molecular Pathways Induced by IL-21 in Human B Cells. The Journal of Immunology 177:12, pages 8381-8392.
Crossref
Valerie Horsley, Dónal O'Carroll, Reuben Tooze, Yasuhide Ohinata, Mitinori Saitou, Tetyana Obukhanych, Michel Nussenzweig, Alexander Tarakhovsky & Elaine Fuchs. (2006) Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland. Cell 126:3, pages 597-609.
Crossref
Wayne TamMario GomezAmy ChadburnJoong W. LeeWing C. ChanDaniel M. Knowles. (2006) Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas. Blood 107:10, pages 4090-4100.
Crossref
Arthur L. Shaffer, George Wright, Liming Yang, John Powell, Vu Ngo, Laurence Lamy, Lloyd T. Lam, R. Eric Davis & Louis M. Staudt. (2006) A library of gene expression signatures to illuminate normal and pathological lymphoid biology. Immunological Reviews 210:1, pages 67-85.
Crossref
Patty Zwollo, Suzanne Cole, Erin Bromage & Stephen Kaattari. (2005) B Cell Heterogeneity in the Teleost Kidney: Evidence for a Maturation Gradient from Anterior to Posterior Kidney. The Journal of Immunology 174:11, pages 6608-6616.
Crossref
Martin SchröderRandal J. Kaufman. (2005) THE MAMMALIAN UNFOLDED PROTEIN RESPONSE. Annual Review of Biochemistry 74:1, pages 739-789.
Crossref
Nicole McNeil, Joong Su Kim, Thomas Ried & Siegfried Janz. (2005) Extraosseous IL-6 transgenic mouse plasmacytoma sometimes lacksMyc-activating chromosomal translocation. Genes, Chromosomes and Cancer 43:2, pages 137-146.
Crossref
Kristen Johnson, Miriam Shapiro-Shelef, Chainarong Tunyaplin & Kathryn Calame. (2005) Regulatory events in early and late B-cell differentiation. Molecular Immunology 42:7, pages 749-761.
Crossref
Miriam Shapiro-Shelef & Kathryn Calame. (2005) Regulation of plasma-cell development. Nature Reviews Immunology 5:3, pages 230-242.
Crossref
Liliana GuedezAntonio MartinezShumei ZhaoAngelica ViveroStefania PittalugaMaryalice Stetler-StevensonMark RaffeldWilliam G. Stetler-Stevenson. (2005) Tissue inhibitor of metalloproteinase 1 (TIMP-1) promotes plasmablastic differentiation of a Burkitt lymphoma cell line: implications in the pathogenesis of plasmacytic/plasmablastic tumors. Blood 105:4, pages 1660-1668.
Crossref
Joseph W Brewer & Linda M Hendershot. (2004) Building an antibody factory: a job for the unfolded protein response. Nature Immunology 6:1, pages 23-29.
Crossref
R. Sciammas & M. M. Davis. 2005. Molecular Analysis of B Lymphocyte Development and Activation. Molecular Analysis of B Lymphocyte Development and Activation 201 224 .
Axel Kallies, Jhagvaral Hasbold, David M. Tarlinton, Wendy Dietrich, Lynn M. Corcoran, Philip D. Hodgkin & Stephen L. Nutt. (2004) Plasma Cell Ontogeny Defined by Quantitative Changes in Blimp-1 Expression. Journal of Experimental Medicine 200:8, pages 967-977.
Crossref
Chainarong Tunyaplin, A. L. Shaffer, Cristina D. Angelin-Duclos, Xin Yu, Louis M. Staudt & Kathryn L. Calame. (2004) Direct Repression of prdm1 by Bcl-6 Inhibits Plasmacytic Differentiation . The Journal of Immunology 173:2, pages 1158-1165.
Crossref
Martin Schröder, Robert Clark, Chuan Yin Liu & Randal J Kaufman. (2004) The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase. The EMBO Journal 23:11, pages 2281-2292.
Crossref
Karin Tarte, Michel Jourdan, Jean Luc Veyrune, Ingolf Berberich, Geneviève Fiol, Nicole Redal, John ShaughnessyJrJr & Bernard Klein. (2004) The Bcl-2 family member Bfl-1/A1 is strongly repressed in normal and malignant plasma cells but is a potent anti-apoptotic factor for myeloma cells. British Journal of Haematology 125:3, pages 373-382.
Crossref
Boris Bartholdy & Patrick Matthias. (2004) Transcriptional control of B cell development and function. Gene 327:1, pages 1-23.
Crossref
Vanitha S. Raman, Rama S. Akondy, Satyajit Rath, Vineeta Bal & Anna George. (2003) Ligation of CD27 on B Cells In Vivo during Primary Immunization Enhances Commitment to Memory B Cell Responses. The Journal of Immunology 171:11, pages 5876-5881.
Crossref
Miriam Shapiro-Shelef, Kuo-I Lin, Louise J McHeyzer-Williams, Jerry Liao, Michael G McHeyzer-Williams & Kathryn Calame. (2003) Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells. Immunity 19:4, pages 607-620.
Crossref
Ian C. M. MacLennan, Kai-Michael Toellner, Adam F. Cunningham, Karine Serre, Daniel M.-Y. Sze, Elina Zúñiga, Matthew C. Cook & Carola G. Vinuesa. (2003) Extrafollicular antibody responses. Immunological Reviews 194:1, pages 8-18.
Crossref
Kuo-I Lin, Chainarong Tunyaplin & Kathryn Calame. (2003) Transcriptional regulatory cascades controlling plasma cell differentiation. Immunological Reviews 194:1, pages 19-28.
Crossref
Karin Tarte, Fenghuang Zhan, John De Vos, Bernard Klein & John ShaughnessyJrJr. (2003) Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation. Blood 102:2, pages 592-600.
Crossref
Gregory H. UnderhillDavid GeorgeEric G. BremerGeoffrey S. Kansas. (2003) Gene expression profiling reveals a highly specialized genetic program of plasma cells. Blood 101:10, pages 4013-4021.
Crossref
Kathryn L. CalameKuo-I LinChainarong Tunyaplin. (2003) Regulatory Mechanisms that Determine the Development and Function of Plasma Cells. Annual Review of Immunology 21:1, pages 205-230.
Crossref
Ildikó Györy, György Fejér, Nilanjan Ghosh, Ed Seto & Kenneth L. Wright. (2003) Identification of a Functionally Impaired Positive Regulatory Domain I Binding Factor 1 Transcription Repressor in Myeloma Cell Lines. The Journal of Immunology 170:6, pages 3125-3133.
Crossref
Cristina Angelin-Duclos, Kristen Johnson, Jerry Liao, Kuo-I Lin & Kathryn Calame. (2002) An interfering form of Blimp-1 increases IgM secreting plasma cells and blocks maturation of peripheral B cells. European Journal of Immunology 32:12, pages 3765-3775.
Crossref
A.L. Shaffer, Kuo-I Lin, Tracy C. Kuo, Xin Yu, Elaine M. Hurt, Andreas Rosenwald, Jena M. Giltnane, Liming Yang, Hong Zhao, Kathryn Calame & Louis M. Staudt. (2002) Blimp-1 Orchestrates Plasma Cell Differentiation by Extinguishing the Mature B Cell Gene Expression Program. Immunity 17:1, pages 51-62.
Crossref
Brian P. O'Connor, Marilia Cascalho & Randolph J. Noelle. (2002) Short-lived and Long-lived Bone Marrow Plasma Cells Are Derived from a Novel Precursor Population. The Journal of Experimental Medicine 195:6, pages 737-745.
Crossref
Kathryn L. Calame. (2001) Plasma cells: finding new light at the end of B cell development. Nature Immunology 2:12, pages 1103-1108.
Crossref
Andreas M. Reimold, Neal N. Iwakoshi, John Manis, Prashanth Vallabhajosyula, Eva Szomolanyi-Tsuda, Ellen M. Gravallese, Daniel Friend, Michael J. Grusby, Frederick Alt & Laurie H. Glimcher. (2001) Plasma cell differentiation requires the transcription factor XBP-1. Nature 412:6844, pages 300-307.
Crossref
Janet F. Piskurich, Kuo -I. Lin, Yi Lin, Ying Wang, Jenny P. -Y. Ting & Kathryn Calame. (2000) BLIMP-1 mediates extinction of major histocompatibility class II transactivator expression in plasma cells. Nature Immunology 1:6, pages 526-532.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.