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Susanne Bacher, Hilda Stekman, Carla M. Farah, Annika Karger, Michael Kracht & M. Lienhard Schmitz. (2021) MEKK1-Dependent Activation of the CRL4 Complex Is Important for DNA Damage-Induced Degradation of p21 and DDB2 and Cell Survival. Molecular and Cellular Biology 41:10.
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Azfar Jamal, Manickavinayaham Swarnalatha, Sarwat Sultana, Prashant Joshi, Subrat K. Panda & Vijay Kumar. (2015) The G1 phase E3 ubiquitin ligase TRUSS that gets deregulated in human cancers is a novel substrate of the S-phase E3 ubiquitin ligase Skp2. Cell Cycle 14:16, pages 2688-2700.
Read now
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Chunhua Han, Gulzar Wani, Ran Zhao, Jiang Qian, Nidhi Sharma, Jinshan He, Qianzheng Zhu, Qi-En Wang & Altaf A Wani. (2015) Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repair. Cell Cycle 14:7, pages 1103-1115.
Read now
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Ornella Cazzalini, Paola Perucca, Roberto Mocchi, Sabrina Sommatis, Ennio Prosperi & Lucia Anna Stivala. (2014) DDB2 association with PCNA is required for its degradation after UV-induced DNA damage. Cell Cycle 13:2, pages 240-248.
Read now
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Tarek Abbas, Mignon Keaton & Anindya Dutta. (2013) Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2. Cell Cycle 12:14, pages 2175-2182.
Read now
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Ling Zhang, Abigail Lubin, Hua Chen, Zhongyi Sun & Feng Gong. (2012) The deubiquitinating protein USP24 interacts with DDB2 and regulates DDB2 stability. Cell Cycle 11:23, pages 4378-4384.
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Zhen Shen & Supriya G. Prasanth. (2012) Orc2 protects ORCA from ubiquitin-mediated degradation. Cell Cycle 11:19, pages 3578-3589.
Read now
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Yiyi Yan, Xiaoshan Zhang & Randy J. Legerski. (2011) Artemis interacts with the Cul4A-DDB1DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27. Cell Cycle 10:23, pages 4098-4109.
Read now
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Sergey Alekseev, Martijn S. Luijsterburg, Alex Pines, Bart Geverts, Pierre-Olivier Mari, Giuseppina Giglia-Mari, Hannes Lans, Adriaan B. Houtsmuller, Leon H. F. Mullenders, Jan H. J. Hoeijmakers & Wim Vermeulen. (2008) Cellular Concentrations of DDB2 Regulate Dynamic Binding of DDB1 at UV-Induced DNA Damage. Molecular and Cellular Biology 28:24, pages 7402-7413.
Read now
Read now
Tanya Stoyanova, Taewon Yoon, Dragana Kopanja, Margalit B. Mokyr & Pradip Raychaudhuri. (2008) The Xeroderma Pigmentosum Group E Gene Product DDB2 Activates Nucleotide Excision Repair by Regulating the Level of p21Waf1/Cip1. Molecular and Cellular Biology 28:1, pages 177-187.
Read now
Read now
Courtney A. Lovejoy, Kimberli Lock, Ashwini Yenamandra & David Cortez. (2006) DDB1 Maintains Genome Integrity through Regulation of Cdt1. Molecular and Cellular Biology 26:21, pages 7977-7990.
Read now
Read now
Tanya Bondar, Anna Kalinina, Lyne Khair, Dragana Kopanja, Alo Nag, Srilata Bagchi & Pradip Raychaudhuri. (2006) Cul4A and DDB1 Associate with Skp2 To Target p27Kip1 for Proteolysis Involving the COP9 Signalosome. Molecular and Cellular Biology 26:7, pages 2531-2539.
Read now
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Gülnihal Kulaksız, Joyce T. Reardon & Aziz Sancar. (2005) Xeroderma Pigmentosum Complementation Group E Protein (XPE/DDB2): Purification of Various Complexes of XPE and Analyses of Their Damaged DNA Binding and Putative DNA Repair Properties. Molecular and Cellular Biology 25:22, pages 9784-9792.
Read now
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Toshiki Itoh, Cristin O'Shea & Stuart Linn. (2003) Impaired Regulation of Tumor Suppressor p53 Caused by Mutations in the Xeroderma Pigmentosum DDB2 Gene: Mutual Regulatory Interactions between p48 and p53. Molecular and Cellular Biology 23:21, pages 7540-7553.
Read now
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Binghui Li, Joseph C. Ruiz & Kristin T. Chun. (2002) CUL-4A Is Critical for Early Embryonic Development. Molecular and Cellular Biology 22:14, pages 4997-5005.
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Articles from other publishers (109)
Martin Grønbæk-Thygesen, Caroline Kampmeyer, Kay Hofmann & Rasmus Hartmann-Petersen. (2023) The moonlighting of RAD23 in DNA repair and protein degradation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1866:2, pages 194925.
Crossref
Crossref
Ning Bao, Jiguang Han & Huimin Zhou. (2022) A protein with broad functions: damage-specific DNA-binding protein 2. Molecular Biology Reports 49:12, pages 12181-12192.
Crossref
Crossref
Neha Jaiswal, Deeptashree Nandi, Pradeep Singh Cheema & Alo Nag. (2022) The anaphase-promoting complex/cyclosome co-activator, Cdh1, is a novel target of human papillomavirus 16 E7 oncoprotein in cervical oncogenesis. Carcinogenesis 43:10, pages 988-1001.
Crossref
Crossref
J. Sweet‐Jones, A. A. Yurchenko, A. V. Igoshin, N. S. Yudin, M. T. Swain & D. M. Larkin. (2020) Resequencing and signatures of selection scan in two Siberian native sheep breeds point to candidate genetic variants for adaptation and economically important traits. Animal Genetics 52:1, pages 126-131.
Crossref
Crossref
Pengbo Zhou & Fan Yan. 2020. Cullin-RING Ligases and Protein Neddylation. Cullin-RING Ligases and Protein Neddylation
225
239
.
Pauline Gilson, Guillaume Drouot, Andréa Witz, Jean-Louis Merlin, Philippe Becuwe & Alexandre Harlé. (2019) Emerging Roles of DDB2 in Cancer. International Journal of Molecular Sciences 20:20, pages 5168.
Crossref
Crossref
Akira Motegi, Mitsuko Masutani, Ken-ichi Yoshioka & Tadayoshi Bessho. (2019) Aberrations in DNA repair pathways in cancer and therapeutic significances. Seminars in Cancer Biology 58, pages 29-46.
Crossref
Crossref
F. Kobaisi, N. Fayyad, H. R. Rezvani, M. Fayyad-Kazan, E. Sulpice, B. Badran, H. Fayyad-Kazan, X. Gidrol & W. Rachidi. (2019) Signaling Pathways, Chemical and Biological Modulators of Nucleotide Excision Repair: The Faithful Shield against UV Genotoxicity. Oxidative Medicine and Cellular Longevity 2019, pages 1-18.
Crossref
Crossref
Tsai-Chun Lai & Meng-Chun Hu. (2019) Regulation of liver receptor homologue-1 by DDB2 E3 ligase activity is critical for hepatic glucose metabolism. Scientific Reports 9:1.
Crossref
Crossref
Ji Cheng, Jianping Guo, Brian J. North, Kaixiong Tao, Pengbo Zhou & Wenyi Wei. (2019) The emerging role for Cullin 4 family of E3 ligases in tumorigenesis. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1871:1, pages 138-159.
Crossref
Crossref
Prashant V. Bommi, Sriram Ravindran, Pradip Raychaudhuri & Srilata Bagchi. (2018) DDB2 regulates Epithelial-to-Mesenchymal Transition (EMT) in Oral/Head and Neck Squamous Cell Carcinoma. Oncotarget 9:78, pages 34708-34718.
Crossref
Crossref
Rince John, Yama Atri, Vaibhav Chand, Neha Jaiswal, Kritika Raj & Alo Nag. (2017) Cell cycle-dependent regulation of cytoglobin by Skp2. FEBS Letters 591:21, pages 3507-3522.
Crossref
Crossref
Chunhua Han, Ran Zhao, John Kroger, Jinshan He, Gulzar Wani, Qi-En WangAltaf A Wani. (2017) UV radiation-induced SUMOylation of DDB2 regulates nucleotide excision repair. Carcinogenesis 38:10, pages 976-985.
Crossref
Crossref
Qianzheng Zhu & Altaf A. Wani. (2017) Nucleotide Excision Repair: Finely Tuned Molecular Orchestra of Early Pre-incision Events. Photochemistry and Photobiology 93:1, pages 166-177.
Crossref
Crossref
Jeong-Min Park & Tae-Hong Kang. (2016) Transcriptional and Posttranslational Regulation of Nucleotide Excision Repair: The Guardian of the Genome against Ultraviolet Radiation. International Journal of Molecular Sciences 17:11, pages 1840.
Crossref
Crossref
Juan Li, Sheng Qin, Huanjun Yu, Jing Zhang, Na Liu, Ye Yu, Chengxiang Hou & Muwang Li. (2016) Comparative Transcriptome Analysis Reveals Different Silk Yields of Two Silkworm Strains. PLOS ONE 11:5, pages e0155329.
Crossref
Crossref
Peter Rüthemann, Chiara Balbo Pogliano & Hanspeter Naegeli. (2016) Global-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo Modifiers. Frontiers in Genetics 7.
Crossref
Crossref
Marjo-Riitta Puumalainen, Peter Rüthemann, Jun-Hyun Min & Hanspeter Naegeli. (2015) Xeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulation. Cellular and Molecular Life Sciences 73:3, pages 547-566.
Crossref
Crossref
Matthew J. Keuss, Yann Thomas, Robin Mcarthur, Nicola T. Wood, Axel Knebel & Thimo Kurz. (2016) Characterisation of the mammalian family of DCN-type NEDD8 E3 ligases. Journal of Cell Science.
Crossref
Crossref
Gondichatnahalli M. Lingaraju, Kerstin Böhm, Julius Rabl, Simone Cavadini, Eric S. Fischer, Susanne A. Kassube & Nicolas H. Thomä. 2016. DNA Replication, Recombination, and Repair. DNA Replication, Recombination, and Repair
211
232
.
Jeffrey Hannah & Pengbo Zhou. (2015) Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B. Gene 573:1, pages 33-45.
Crossref
Crossref
Loes van Cuijk, Gijsbert J. van Belle, Yasemin Turkyilmaz, Sara L. Poulsen, Roel C. Janssens, Arjan F. Theil, Mariangela Sabatella, Hannes Lans, Niels Mailand, Adriaan B. Houtsmuller, Wim Vermeulen & Jurgen A. Marteijn. (2015) SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair. Nature Communications 6:1.
Crossref
Crossref
Lanyang Gao, Shuzhang Yang, Yunye Zhu, Junfang Zhang, Ming Zhuo, Ming Miao, Xiaofeng Tang, Yongsheng Liu & Songhu Wang. (2015) The tomato DDI2, a PCNA ortholog, associating with DDB1-CUL4 complex is required for UV-damaged DNA repair and plant tolerance to UV stress. Plant Science 235, pages 101-110.
Crossref
Crossref
Sergey Alekseev & Frédéric Coin. (2015) Orchestral maneuvers at the damaged sites in nucleotide excision repair. Cellular and Molecular Life Sciences 72:11, pages 2177-2186.
Crossref
Crossref
Bruno César Feltes & Diego Bonatto. (2015) Overview of xeroderma pigmentosum proteins architecture, mutations and post-translational modifications. Mutation Research/Reviews in Mutation Research 763, pages 306-320.
Crossref
Crossref
Rince John, Vaibhav Chand, Sankalpa Chakraborty, Neha Jaiswal & Alo Nag. (2014) DNA damage induced activation of Cygb stabilizes p53 and mediates G1 arrest. DNA Repair 24, pages 107-112.
Crossref
Crossref
Marjo-Riitta Puumalainen, Davor Lessel, Peter Rüthemann, Nina Kaczmarek, Karin Bachmann, Kristijan Ramadan & Hanspeter Naegeli. (2014) Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity. Nature Communications 5:1.
Crossref
Crossref
Puneet Sharma & Alo Nag. (2014) CUL4A ubiquitin ligase: a promising drug target for cancer and other human diseases. Open Biology 4:2, pages 130217.
Crossref
Crossref
Shuhei Kotoshiba, Lakshmi Gopinathan, Elisabeth Pfeiffenberger, Anisa Rahim, Leah A. Vardy, Keiko Nakayama, Keiichi I. Nakayama & Philipp Kaldis. (2014) p27 is regulated independently of Skp2 in the absence of Cdk2. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:2, pages 436-445.
Crossref
Crossref
Alessio Colantoni, Valerio Bianchi, Pier Federico Gherardini, Gianpaolo Scalia Tomba, Gabriele Ausiello, Manuela Helmer-Citterich & Fabrizio Ferrè. (2013) Alternative splicing tends to avoid partial removals of protein-protein interaction sites. BMC Genomics 14:1.
Crossref
Crossref
Maasa Tsuge, Yusuke Masuda, Hidenori Kaneoka, Shunsuke Kidani, Katsuhide Miyake & Shinji Iijima. (2013) SUMOylation of damaged DNA-binding protein DDB2. Biochemical and Biophysical Research Communications 438:1, pages 26-31.
Crossref
Crossref
Nilotpal Roy, Prashant V. Bommi, Uppoor G. Bhat, Shaumick Bhattacharjee, Indira Elangovan, Jing Li, Krushna C. Patra, Dragana Kopanja, Adam Blunier, Richard Benya, Srilata Bagchi & Pradip Raychaudhuri. (2013) DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer. Cancer Research 73:12, pages 3771-3782.
Crossref
Crossref
Tarek Abbas, Adam C. Mueller, Etsuko Shibata, Mignon Keaton, Mario Rossi & Anindya Dutta. (2013) CRL1-FBXO11 Promotes Cdt2 Ubiquitylation and Degradation and Regulates Pr-Set7/Set8-Mediated Cellular Migration. Molecular Cell 49:6, pages 1147-1158.
Crossref
Crossref
Jason Lehman & Lindsey Mayo. (2012) Integration of DNA Damage and Repair with Murine Double-Minute 2 (Mdm2) in Tumorigenesis. International Journal of Molecular Sciences 13:12, pages 16373-16386.
Crossref
Crossref
Joanne I. YehArthur S. Levine, Shoucheng DuUnmesh ChinteHarshad Ghodke, Hong Wang, Haibin ShiChing L. Hsieh, James F. ConwayBennett Van Houten & Vesna Rapić-Otrin. (2012) Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proceedings of the National Academy of Sciences 109:41.
Crossref
Crossref
Nilotpal Roy, Srilata Bagchi & Pradip Raychaudhuri. (2012) Damaged DNA Binding Protein 2 in Reactive Oxygen Species (ROS) Regulation and Premature Senescence. International Journal of Molecular Sciences 13:9, pages 11012-11026.
Crossref
Crossref
N. Sjakste, K. Bielskiene, L. Bagdoniene, D. Labeikyte, A. Gutcaits, Y. Vassetzky & T. Sjakste. (2012) Tightly bound to DNA proteins: Possible universal substrates for intranuclear processes. Gene 492:1, pages 54-64.
Crossref
Crossref
John J. Turchi & Steve M. Patrick. 2012. DNA Repair in Cancer Therapy. DNA Repair in Cancer Therapy
109
117
.
Jia Fei, Nina Kaczmarek, Andreas Luch, Andreas Glas, Thomas Carell & Hanspeter Naegeli. (2011) Regulation of Nucleotide Excision Repair by UV-DDB: Prioritization of Damage Recognition to Internucleosomal DNA. PLoS Biology 9:10, pages e1001183.
Crossref
Crossref
Andrea Scrima, Eric S. Fischer, Gondichatnahalli M. Lingaraju, Kerstin Böhm, Simone Cavadini & Nicolas H. Thomä. (2011) Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best!. FEBS Letters 585:18, pages 2818-2825.
Crossref
Crossref
Xiaoli LUO, Xiangli NIU, Weizao HUANG & Yongsheng LIU. (2011) Expression Characteristics and Functional Analysis of <I>DDB1</I> Gene in <I>Oryza sativa</I>*. Chinese Journal of Appplied Environmental Biology 17:1, pages 1-6.
Crossref
Crossref
Enric Castells, Jean Molinier, Giovanna Benvenuto, Clara Bourbousse, Gerald Zabulon, Antoine Zalc, Stefano Cazzaniga, Pascal Genschik, Fredy Barneche & Chris Bowler. (2011)
The conserved factor DE-ETIOLATED 1 cooperates with CUL4-DDB1
DDB2
to maintain genome integrity upon UV stress
. The EMBO Journal 30:6, pages 1162-1172.
Crossref
Crossref
Ian R. Watson, Meredith S. Irwin & Michael Ohh. (2011) NEDD8 Pathways in Cancer, Sine Quibus Non. Cancer Cell 19:2, pages 168-176.
Crossref
Crossref
Kristi L. Jones, Ling Zhang, Kenneth L. Seldeen & Feng Gong. (2010) Detection of bulky DNA lesions: DDB2 at the interface of chromatin and DNA repair in eukaryotes. IUBMB Life 62:11, pages 803-811.
Crossref
Crossref
N. Sjakste, L. Bagdoniene, A. Gutcaits, D. Labeikyte, K. Bielskiene, I. Trapina, I. Muiznieks, Y. Vassetzky & T. Sjakste. (2010) Proteins tightly bound to DNA: New data and old problems. Biochemistry (Moscow) 75:10, pages 1240-1251.
Crossref
Crossref
Aziz Sancar, Laura A. Lindsey-Boltz, Tae-Hong Kang, Joyce T. Reardon, Jin Hyup Lee & Nuri Ozturk. (2010) Circadian clock control of the cellular response to DNA damage. FEBS Letters 584:12, pages 2618-2625.
Crossref
Crossref
Ti Li, Eva I Robert, Pieter C van Breugel, Michel Strubin & Ning Zheng. (2009) A promiscuous α-helical motif anchors viral hijackers and substrate receptors to the CUL4–DDB1 ubiquitin ligase machinery. Nature Structural & Molecular Biology 17:1, pages 105-111.
Crossref
Crossref
Sarah Jackson & Yue Xiong. (2009) CRL4s: the CUL4-RING E3 ubiquitin ligases. Trends in Biochemical Sciences 34:11, pages 562-570.
Crossref
Crossref
D Kopanja, T Stoyanova, M N Okur, E Huang, S Bagchi & P Raychaudhuri. (2009) Proliferation defects and genome instability in cells lacking Cul4A. Oncogene 28:26, pages 2456-2465.
Crossref
Crossref
Liren Liu, Sharrell Lee, Jianxuan Zhang, Sara B. Peters, Jeffrey Hannah, Yue Zhang, Yan Yin, Andrew Koff, Liang Ma & Pengbo Zhou. (2009) CUL4A Abrogation Augments DNA Damage Response and Protection against Skin Carcinogenesis. Molecular Cell 34:4, pages 451-460.
Crossref
Crossref
Ulrike Camenisch & Hanspeter Naegeli. 2009. Molecular, Clinical and Environmental Toxicology. Molecular, Clinical and Environmental Toxicology
111
150
.
Drew Bennett & Toshiki Itoh. 2009. Molecular Mechanisms of Xeroderma Pigmentosum. Molecular Mechanisms of Xeroderma Pigmentosum
57
64
.
Qun Zhao, Bassant M. Barakat, Song Qin, Alo Ray, Mohamed A. El-Mahdy, Gulzar Wani, El-Shaimaa Arafa, Safita N. Mir, Qi-En Wang & Altaf A. Wani. (2008) The p38 Mitogen-activated Protein Kinase Augments Nucleotide Excision Repair by Mediating DDB2 Degradation and Chromatin Relaxation. Journal of Biological Chemistry 283:47, pages 32553-32561.
Crossref
Crossref
David L. WaningBinghui LiNan JiaYahaira Naaldijk, W. Scott GoebelHarm HogenEsch & Kristin T. Chun. (2008) Cul4A is required for hematopoietic cell viability and its deficiency leads to apoptosis. Blood 112:2, pages 320-329.
Crossref
Crossref
Jean Molinier, Esther Lechner, Eva Dumbliauskas & Pascal Genschik. (2008) Regulation and Role of Arabidopsis CUL4-DDB1A-DDB2 in Maintaining Genome Integrity upon UV Stress. PLoS Genetics 4:6, pages e1000093.
Crossref
Crossref
Zilal Kattan, Sophie Marchal, Emilie Brunner, Carole Ramacci, Agnès Leroux, Jean Louis Merlin, Lionel Domenjoud, Michel Dauça & Philippe Becuwe. (2008) Damaged DNA Binding Protein 2 Plays a Role in Breast Cancer Cell Growth. PLoS ONE 3:4, pages e2002.
Crossref
Crossref
Olivier Maillard, Ulrike Camenisch, Krastan B. Blagoev & Hanspeter Naegeli. (2008) Versatile protection from mutagenic DNA lesions conferred by bipartite recognition in nucleotide excision repair. Mutation Research/Reviews in Mutation Research 658:3, pages 271-286.
Crossref
Crossref
Joel Fernandes Lima, Iran Malavazi, Márcia Eliana da Silva Ferreira, Marcela Savoldi, André Oliveira MotaJrJr, José Luiz Capellaro, Maria Helena de Souza Goldman & Gustavo Henrique Goldman. (2007) Functional characterization of the putative Aspergillus nidulans DNA damage binding protein homologue DdbA. Molecular Genetics and Genomics 279:3, pages 239-253.
Crossref
Crossref
Martijn S. Luijsterburg, Joachim Goedhart, Jill Moser, Hanneke Kool, Bart Geverts, Adriaan B. Houtsmuller, Leon H. F. Mullenders, Wim Vermeulen & Roel van Driel. (2007) Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC. Journal of Cell Science 120:15, pages 2706-2716.
Crossref
Crossref
Qi-En Wang, Mette Prætorius-Ibba, Qianzheng Zhu, Mohamed A. El-Mahdy, Gulzar Wani, Qun Zhao, Song Qin, Srinivas Patnaik & Altaf A. Wani. (2007) Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair. Nucleic Acids Research 35:16, pages 5338-5350.
Crossref
Crossref
Rebecca A. Bish & Michael P. Myers. (2007) Werner Helicase-interacting Protein 1 Binds Polyubiquitin via Its Zinc Finger Domain. Journal of Biological Chemistry 282:32, pages 23184-23193.
Crossref
Crossref
S Prost, P Lu, H Caldwell & D Harrison. (2006) E2F regulates DDB2: consequences for DNA repair in Rb-deficient cells. Oncogene 26:24, pages 3572-3581.
Crossref
Crossref
Pei-hsin Hsu, Philip C. Hanawalt & Thierry Nouspikel. (2007) Nucleotide excision repair phenotype of human acute myeloid leukemia cell lines at various stages of differentiation. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 614:1-2, pages 3-15.
Crossref
Crossref
Stephane Angers, Ti Li, Xianhua Yi, Michael J. MacCoss, Randall T. Moon & Ning Zheng. (2006) Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery. Nature 443:7111, pages 590-593.
Crossref
Crossref
Jinyou Li, Qi-En Wang, Qianzheng Zhu, Mohamed A. El-Mahdy, Gulzar Wani, Mette Prætorius-Ibba & Altaf A. Wani. (2006) DNA Damage Binding Protein Component DDB1 Participates in Nucleotide Excision Repair through DDB2 DNA-binding and Cullin 4A Ubiquitin Ligase Activity. Cancer Research 66:17, pages 8590-8597.
Crossref
Crossref
Binghui LiNan JiaReuben KapurKristin T. Chun. (2006) Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis. Blood 107:11, pages 4291-4299.
Crossref
Crossref
Mohamed A. El-Mahdy, Qianzheng Zhu, Qi-en Wang, Gulzar Wani, Mette Prætorius-Ibba & Altaf A. Wani. (2006) Cullin 4A-mediated Proteolysis of DDB2 Protein at DNA Damage Sites Regulates in Vivo Lesion Recognition by XPC. Journal of Biological Chemistry 281:19, pages 13404-13411.
Crossref
Crossref
Xiaoai Chen, Jianxuan Zhang, Jennifer Lee, Patrick S. Lin, James M. Ford, Ning Zheng & Pengbo Zhou. (2006) A Kinase-Independent Function of c-Abl in Promoting Proteolytic Destruction of Damaged DNA Binding Proteins. Molecular Cell 22:4, pages 489-499.
Crossref
Crossref
Maria G. Kapetanaki, Jennifer Guerrero-Santoro, Dawn C. Bisi, Ching L. Hsieh, Vesna Rapić-Otrin & Arthur S. Levine. (2006)
The DDB1-CUL4A
DDB2
ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites
. Proceedings of the National Academy of Sciences 103:8, pages 2588-2593.
Crossref
Crossref
Ludovic C. J. Gillet & Orlando D. Schärer. (2005) Molecular Mechanisms of Mammalian Global Genome Nucleotide Excision Repair. Chemical Reviews 106:2, pages 253-276.
Crossref
Crossref
Katharine S. Richardson & Wayne Zundel. (2005) The Emerging Role of the COP9 Signalosome in Cancer. Molecular Cancer Research 3:12, pages 645-653.
Crossref
Crossref
Errol C. Friedberg, Graham C. Walker, Wolfram Siede, Richard D. Wood, Roger A. Schultz & Tom Ellenberger. 2005. DNA Repair and Mutagenesis. DNA Repair and Mutagenesis
267
315
.
Dennis H. Oh & Kelvin Yeh. (2005) Differentiating human keratinocytes are deficient in p53 but retain global nucleotide excision repair following ultraviolet radiation. DNA Repair 4:10, pages 1149-1159.
Crossref
Crossref
Christina M. Ulane, Alex Kentsis, Cristian D. Cruz, Jean-Patrick Parisien, Kristi L. Schneider & Curt M. Horvath. (2005) Composition and Assembly of STAT-Targeting Ubiquitin Ligase Complexes: Paramyxovirus V Protein Carboxyl Terminus Is an Oligomerization Domain. Journal of Virology 79:16, pages 10180-10189.
Crossref
Crossref
Peter J. Horn, Jean-Noël Bastie & Craig L. Peterson. (2005) A Rik1-associated, cullin-dependent E3 ubiquitin ligase is essential for heterochromatin formation. Genes & Development 19:14, pages 1705-1714.
Crossref
Crossref
Jill Moser, Marcel Volker, Hanneke Kool, Sergei Alekseev, Harry Vrieling, Akira Yasui, Albert A. van Zeeland & Leon H.F. Mullenders. (2005) The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions. DNA Repair 4:5, pages 571-582.
Crossref
Crossref
Noriyuki Matsuda, Keiko Azuma, Masafumi Saijo, Shun-ichiro Iemura, Yusaku Hioki, Tohru Natsume, Tomoki Chiba, Kiyoji Tanaka & Keiji Tanaka. (2005) DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex. DNA Repair 4:5, pages 537-545.
Crossref
Crossref
Taewon Yoon, Amit Chakrabortty, Roberta Franks, Ted Valli, Hiroaki Kiyokawa & Pradip Raychaudhuri. (2004) Tumor-prone phenotype of the DDB2-deficient mice. Oncogene 24:3, pages 469-478.
Crossref
Crossref
Alo Nag, Srilata Bagchi & Pradip Raychaudhuri. (2004) Cul4A Physically Associates with MDM2 and Participates in the Proteolysis of p53. Cancer Research 64:22, pages 8152-8155.
Crossref
Crossref
Timothy D. Donaldson, Maher A. Noureddine, Patrick J. Reynolds, William Bradford & Robert J. Duronio. (2004)
Targeted Disruption of
Drosophila
Roc1b Reveals Functional Differences in the Roc Subunit of Cullin-dependent E3 Ubiquitin Ligases
. Molecular Biology of the Cell 15:11, pages 4892-4903.
Crossref
Crossref
Ramiro Dip, Ulrike Camenisch & Hanspeter Naegeli. (2004) Mechanisms of DNA damage recognition and strand discrimination in human nucleotide excision repair. DNA Repair 3:11, pages 1409-1423.
Crossref
Crossref
Andrew R. Willems, Michael Schwab & Mike Tyers. (2004) A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1695:1-3, pages 133-170.
Crossref
Crossref
Jian Hu, Chad M. McCall, Tomohiko Ohta & Yue Xiong. (2004) Targeted ubiquitination of CDT1 by the DDB1–CUL4A–ROC1 ligase in response to DNA damage. Nature Cell Biology 6:10, pages 1003-1009.
Crossref
Crossref
Yuki Yanagawa, James A. Sullivan, Setsuko Komatsu, Giuliana Gusmaroli, Genki Suzuki, Jianning Yin, Toyotaka Ishibashi, Yusuke Saijo, Vicente Rubio, Seisuke Kimura, Jian Wang & Xing Wang Deng. (2004)
Arabidopsis
COP10 forms a complex with DDB1 and DET1 in vivo and enhances the activity of ubiquitin conjugating enzymes
. Genes & Development 18:17, pages 2172-2181.
Crossref
Crossref
Curt M. Horvath. (2004) Silencing STATs: lessons from paramyxovirus interferon evasion. Cytokine & Growth Factor Reviews 15:2-3, pages 117-127.
Crossref
Crossref
Daniele Guardavaccaro & Michele Pagano. (2004) Oncogenic aberrations of cullin-dependent ubiquitin ligases. Oncogene 23:11, pages 2037-2049.
Crossref
Crossref
Tomohiko Ohta & Mamoru Fukuda. (2004) Ubiquitin and breast cancer. Oncogene 23:11, pages 2079-2088.
Crossref
Crossref
Tanya Bondar, Aleksandr Ponomarev & Pradip Raychaudhuri. (2004) Ddb1 Is Required for the Proteolysis of the Schizosaccharomyces pombe Replication Inhibitor Spd1 during S Phase and after DNA Damage. Journal of Biological Chemistry 279:11, pages 9937-9943.
Crossref
Crossref
Ingrid E. WertzKaren M. O'RourkeZemin ZhangDavid DornanDavid ArnottRaymond J. DeshaiesVishva M. Dixit. (2004) Human De-Etiolated-1 Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase. Science 303:5662, pages 1371-1374.
Crossref
Crossref
Toshiki Itoh, Dragana Cado, Ryoichi Kamide & Stuart Linn. (2004) DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen. Proceedings of the National Academy of Sciences 101:7, pages 2052-2057.
Crossref
Crossref
Susan L. Holbeck & Edward A. Sausville. 2004. Proteasome Inhibitors in Cancer Therapy. Proteasome Inhibitors in Cancer Therapy
99
107
.
Yoshito Nagano, Hiroshi Yamashita, Tetsuya Takahashi, Shosei Kishida, Takeshi Nakamura, Eizo Iseki, Nobutaka Hattori, Yoshikuni Mizuno, Akira Kikuchi & Masayasu Matsumoto. (2003) Siah-1 Facilitates Ubiquitination and Degradation of Synphilin-1. Journal of Biological Chemistry 278:51, pages 51504-51514.
Crossref
Crossref
Birgitte Ø. Wittschieben & Richard D. Wood. (2003) DDB complexities. DNA Repair 2:9, pages 1065-1069.
Crossref
Crossref
Maureen E. Fitch, Irina V. Cross, Stephanie J. Turner, Shanthi Adimoolam, Cindy X. Lin, Kevin G. Williams & James M. Ford. (2003) The DDB2 nucleotide excision repair gene product p48 enhances global genomic repair in p53 deficient human fibroblasts. DNA Repair 2:7, pages 819-826.
Crossref
Crossref
Olivier Leupin, Séverine Bontron & Michel Strubin. (2003) Hepatitis B Virus X Protein and Simian Virus 5 V Protein Exhibit Similar UV-DDB1 Binding Properties To Mediate Distinct Activities. Journal of Virology 77:11, pages 6274-6283.
Crossref
Crossref
Cong Liu, Kelly A. Powell, Kirsten Mundt, LeJung Wu, Antony M. Carr & Thomas Caspari. (2003) Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms. Genes & Development 17:9, pages 1130-1140.
Crossref
Crossref
Regina Groisman, Jolanta Polanowska, Isao Kuraoka, Jun-ichi Sawada, Masafumi Saijo, Ronny Drapkin, Alexei F. Kisselev, Kiyoji Tanaka & Yoshihiro Nakatani. (2003) The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage. Cell 113:3, pages 357-367.
Crossref
Crossref
Ji-Won Hwang, Kyoeng-Woo Min, Taka-aki Tamura & Jong-Bok Yoon. (2003) TIP120A associates with unneddylated cullin 1 and regulates its neddylation. FEBS Letters 541:1-3, pages 102-108.
Crossref
Crossref
Toyotaka Ishibashi, Seisuke Kimura, Taichi Yamamoto, Tomoyuki Furukawa, Kei-ichi Takata, Yukinobu Uchiyama, Junji Hashimoto & Kengo Sakaguchi. (2003) Rice UV-damaged DNA binding protein homologues are most abundant in proliferating tissues. Gene 308, pages 79-87.
Crossref
Crossref
Binghui LiFeng-Chun YangD. Wade ClappKristin T. Chun. (2003) Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle. Blood 101:5, pages 1769-1776.
Crossref
Crossref
DongTao Fu, Mitsuo Wakasugi, Yasuhito Ishigaki, Osamu Nikaido & Tsukasa Matsunaga. (2003) cDNA Cloning of the Chicken DDB1 Gene Encoding the p127 Subunit of Damaged DNA-binding Protein. Genes & Genetic Systems 78:2, pages 169-177.
Crossref
Crossref
Christina M. Ulane & Curt M. Horvath. (2002) Paramyxoviruses SV5 and HPIV2 Assemble STAT Protein Ubiquitin Ligase Complexes from Cellular Components. Virology 304:2, pages 160-166.
Crossref
Crossref
J. Andrejeva, E. Poole, D. F. Young, S. Goodbourn & R. E. Randall. (2002) The p127 Subunit (DDB1) of the UV-DNA Damage Repair Binding Protein Is Essential for the Targeted Degradation of STAT1 by the V Protein of the Paramyxovirus Simian Virus 5. Journal of Virology 76:22, pages 11379-11386.
Crossref
Crossref
Francesca Zolezzi, Jill Fuss, Satoru Uzawa & Stuart Linn. (2002) Characterization of a Schizosaccharomyces pombeStrain Deleted for a Sequence Homologue of the Human Damaged DNA Binding 1 (DDB1) Gene. Journal of Biological Chemistry 277:43, pages 41183-41191.
Crossref
Crossref
Séverine Bontron, Nathalie Lin-Marq & Michel Strubin. (2002) Hepatitis B Virus X Protein Associated with UV-DDB1 Induces Cell Death in the Nucleus and Is Functionally Antagonized by UV-DDB2. Journal of Biological Chemistry 277:41, pages 38847-38854.
Crossref
Crossref
Ya-Juan Zheng, Tetsushi Furukawa, Takehiko Ogura, Kimitaka Tajimi & Nobuya Inagaki. (2002) M Phase-specific Expression and Phosphorylation-dependent Ubiquitination of the ClC-2 Channel. Journal of Biological Chemistry 277:35, pages 32268-32273.
Crossref
Crossref
Jean Tang & Gilbert Chu. (2002) Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein. DNA Repair 1:8, pages 601-616.
Crossref
Crossref
Françoise Bergametti, Delphine Sitterlin & Catherine Transy. (2002) Turnover of Hepatitis B Virus X Protein Is Regulated by Damaged DNA-Binding Complex. Journal of Virology 76:13, pages 6495-6501.
Crossref
Crossref
Jean-Patrick Parisien, Joe F. Lau, Jason J. Rodriguez, Christina M. Ulane & Curt M. Horvath. (2002) Selective STAT Protein Degradation Induced by Paramyxoviruses Requires both STAT1 and STAT2 but Is Independent of Alpha/Beta Interferon Signal Transduction. Journal of Virology 76:9, pages 4190-4198.
Crossref
Crossref