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Mammalian Genetic Models with Minimal or Complex Phenotypes

Mice Deficient for the Wild-Type p53-Induced Phosphatase Gene (Wip1) Exhibit Defects in Reproductive Organs, Immune Function, and Cell Cycle Control

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Pages 1094-1105 | Received 08 Aug 2001, Accepted 12 Nov 2001, Published online: 28 Mar 2023

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Lu Shi, Qianchuan Tian, Chang Feng, Peng Zhang & Yong Zhao. (2020) The biological function and the regulatory roles of wild-type p53-induced phosphatase 1 in immune system. International Reviews of Immunology 39:6, pages 280-291.
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Libor Macurek, Jan Benada, Erik Müllers, Vincentius A. Halim, Kateřina Krejčíková, Kamila Burdová, Sona Pecháčková, Zdeněk Hodný, Arne Lindqvist, René H. Medema & Jiri Bartek. (2013) Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis. Cell Cycle 12:2, pages 251-262.
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Matthew Fletcher Jones & Ashish Lal. (2012) MicroRNAs, wild-type and mutant p53: More questions than answers. RNA Biology 9:6, pages 781-791.
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Chamutal Bornstein, Ran Brosh, Alina Molchadsky, Shalom Madar, Ira Kogan-Sakin, Ido Goldstein, Deepavali Chakravarti, Elsa R. Flores, Naomi Goldfinger, Rachel Sarig & Varda Rotter. (2011) SPATA18, a Spermatogenesis-Associated Gene, Is a Novel Transcriptional Target of p53 and p63. Molecular and Cellular Biology 31:8, pages 1679-1689.
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Su Zhou, Yueyue Xi, Yingying Chen, Fangfang Fu, Wei Yan, Milu Li, Yaling Wu, Aiyue Luo, Ya Li & Shixuan Wang. (2022) Low WIP1 Expression Accelerates Ovarian Aging by Promoting Follicular Atresia and Primordial Follicle Activation. Cells 11:23, pages 3920.
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Yuuki Kozakai, Rui Kamada, Yuhei Kiyota, Fumihiko Yoshimura, Keiji Tanino & Kazuyasu Sakaguchi. (2014) Inhibition of C-terminal truncated PPM1D enhances the effect of doxorubicin on cell viability in human colorectal carcinoma cell line. Bioorganic & Medicinal Chemistry Letters 24:24, pages 5593-5596.
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Jeong Hyeon Park, Tracy K. Hale, Rebecca Jane Smith & Tian Yang. (2014) PPM1B depletion induces premature senescence in human IMR-90 fibroblasts. Mechanisms of Ageing and Development 138, pages 45-52.
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