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Cell Growth and Development

p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes

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Pages 7285-7290 | Received 27 Feb 2003, Accepted 09 Jul 2003, Published online: 27 Mar 2023

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Sharon Brookes, Sladjana Gagrica, Elaine Sanij, Janice Rowe, Fiona J Gregory, Eiji Hara & Gordon Peters. (2015) Evidence for a CDK4-dependent checkpoint in a conditional model of cellular senescence. Cell Cycle 14:8, pages 1164-1173.
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Sabine Paternot, Bianca Colleoni, Xavier Bisteau & Pierre P Roger. (2014) The CDK4/CDK6 inhibitor PD0332991 paradoxically stabilizes activated cyclin D3-CDK4/6 complexes. Cell Cycle 13:18, pages 2879-2888.
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Antonio Cerqueira, Alberto Martín, Catherine E. Symonds, Junko Odajima, Pierre Dubus, Mariano Barbacid & David Santamaría. (2014) Genetic Characterization of the Role of the Cip/Kip Family of Proteins as Cyclin-Dependent Kinase Inhibitors and Assembly Factors. Molecular and Cellular Biology 34:8, pages 1452-1459.
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Laurence Bockstaele, Xavier Bisteau, Sabine Paternot & Pierre P. Roger. (2009) Differential Regulation of Cyclin-Dependent Kinase 4 (CDK4) and CDK6, Evidence that CDK4 Might Not Be Activated by CDK7, and Design of a CDK6 Activating Mutation. Molecular and Cellular Biology 29:15, pages 4188-4200.
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Arpita Ray, Melissa K. James, Stéphane Larochelle, Robert P. Fisher & Stacy W. Blain. (2009) p27Kip1 Inhibits Cyclin D-Cyclin-Dependent Kinase 4 by Two Independent Modes. Molecular and Cellular Biology 29:4, pages 986-999.
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Michelle D. Larrea, Jiyong Liang, Thiago Da Silva, Feng Hong, Shan H. Shao, Kathy Han, D. Dumont & Joyce M. Slingerland. (2008) Phosphorylation of p27Kip1 Regulates Assembly and Activation of Cyclin D1-Cdk4. Molecular and Cellular Biology 28:20, pages 6462-6472.
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Melissa K. James, Arpita Ray, Dina Leznova & Stacy W. Blain. (2008) Differential Modification of p27Kip1 Controls Its Cyclin D-cdk4 Inhibitory Activity. Molecular and Cellular Biology 28:1, pages 498-510.
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Laurence Bockstaele, Hugues Kooken, Frederick Libert, Sabine Paternot, Jacques E. Dumont, Yvan de Launoit, Pierre P. Roger & Katia Coulonval. (2006) Regulated Activating Thr172 Phosphorylation of Cyclin-Dependent Kinase 4(CDK4): Its Relationship with Cyclins and CDK “Inhibitors”. Molecular and Cellular Biology 26:13, pages 5070-5085.
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Xin-Hai Pei, Feng Bai, Tateki Tsutsui, Hiroaki Kiyokawa & Yue Xiong. (2004) Genetic Evidence for Functional Dependency of p18 on Cdk4. Molecular and Cellular Biology 24:15, pages 6653-6664.
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