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Molecular and Cellular Biology Volume 23, 2003 - Issue 22
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Mammalian Genetic Models with Minimal or Complex Phenotypes

EphA3 Null Mutants Do Not Demonstrate Motor Axon Guidance Defects

Ashish Vaidya1 Stem Cell Biology and Regenerative Medicine and Biotherapeutics Research Groups, Robarts Research Institute;2 Department of Physiology and Pharmacology, University of Western Ontario, London, OntarioN6A 5K8, Canada
,
Anna Pniak1 Stem Cell Biology and Regenerative Medicine and Biotherapeutics Research Groups, Robarts Research Institute;2 Department of Physiology and Pharmacology, University of Western Ontario, London, OntarioN6A 5K8, Canada
,
Greg Lemke3 Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, La Jolla, California
&
Arthur Brown1 Stem Cell Biology and Regenerative Medicine and Biotherapeutics Research Groups, Robarts Research Institute;2 Department of Physiology and Pharmacology, University of Western Ontario, London, OntarioN6A 5K8, CanadaCorrespondence[email protected]
Pages 8092-8098 | Received 18 Nov 2002, Accepted 24 Feb 2003, Published online: 27 Mar 2023

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Jenni Lahtela, Laura B. Corson, Annabrita Hemmes, Matthew J. Brauer, Sonja Koopal, James Lee, Thomas L. Hunsaker, Peter K. Jackson & Emmy W. Verschuren. (2013) A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Cell Cycle 12:4, pages 625-634.
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Niamh Keane, Ciara Freeman, Ronan Swords & Francis J Giles. (2012) EPHA3 as a novel therapeutic target in the hematological malignancies. Expert Review of Hematology 5:3, pages 325-340.
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Articles from other publishers (14)

Adriana C. Pliego Zamora, Hansini Ranasinghe, Jessica E. Lisle, Chun Ki Ng, Stephen Huang, Racheal Wadlow, Andrew M. Scott, Andrew W. Boyd & Christopher I. Slape. (2021) Cell-Extrinsic Differentiation Block Mediated by EphA3 in Pre-Leukaemic Thymus Contributes to Disease Progression. Cancers 13:15, pages 3858.
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Míriam Javier-Torrent, Sergi Marco, Daniel Rocandio, Maria Pons-Vizcarra, Peter W Janes, Martin Lackmann, Joaquim Egea & Carlos A Saura. (2019) Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA. eLife 8.
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Elena Andretta, Fernando Cartón-García, Águeda Martínez-Barriocanal, Priscila Guimarães de Marcondes, Lizbeth M. Jimenez-Flores, Irati Macaya, Sarah Bazzocco, Josipa Bilic, Paulo Rodrigues, Rocio Nieto, Stefania Landolfi, Santiago Ramon y Cajal, Simo Schwartz, Arthur Brown, Higinio Dopeso & Diego Arango. (2017) Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer. Scientific Reports 7:1.
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Jenni LahtelaBarun PradhanKatja NärhiAnnabrita HemmesMerja SärkiojaPanu E. KovanenArthur Brown & Emmy W. Verschuren. (2015) The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis . Disease Models & Mechanisms.
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Martin Holcmann, Nicole Amberg, Barbara Drobits, Elisabeth Glitzner, Karin Komposch, Jonathan Robson, Fabio Savarese, Sriram Srivatsa, Gabriel Stulnig & Maria Sibilia. 2015. Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease. Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease 279 438 .
Puja Agrawal, Michael Wang, Seungil Kim, Ace E. Lewis & Jeffrey O. Bush. (2014) Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate . Developmental Dynamics 243:11, pages 1470-1476.
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Leann H. Brennaman, Xuying Zhang, Hanjun Guan, Jason W. Triplett, Arthur Brown, Galina P. Demyanenko, Paul B. Manis, Lynn Landmesser & Patricia F. Maness. (2013) Polysialylated NCAM and EphrinA/EphA Regulate Synaptic Development of GABAergic Interneurons in Prefrontal Cortex. Cerebral Cortex 23:1, pages 162-177.
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Liang Wang, Rüdiger Klein, Binhai Zheng & Till Marquardt. (2011) Anatomical Coupling of Sensory and Motor Nerve Trajectory via Axon Tracking. Neuron 71:2, pages 263-277.
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Katerina V. Savelieva, Indrani Rajan, Kevin B. Baker, Peter Vogel, Wendy Jarman, Margaret Allen & Thomas H. Lanthorn. (2008) Learning and memory impairment in Eph receptor A6 knockout mice. Neuroscience Letters 438:2, pages 205-209.
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Benjamin W. GallardaDario BonanomiDaniel MüllerArthur BrownWilliam A. AlaynickShane E. AndrewsGreg LemkeSamuel L. PfaffTill Marquardt. (2008) Segregation of Axial Motor and Sensory Pathways via Heterotypic Trans-Axonal Signaling. Science 320:5873, pages 233-236.
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Lesley J. Stephen, Amy L. Fawkes, Adam Verhoeve, Greg Lemke & Arthur Brown. (2007) A critical role for the EphA3 receptor tyrosine kinase in heart development. Developmental Biology 302:1, pages 66-79.
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Michael Reber, Robert Hindges & Greg Lemke. 2007. Axon Growth and Guidance. Axon Growth and Guidance 32 49 .
Margarita Irizarry-RamírezChristopher A. WillsonLillian Cruz-OrengoJohnny FigueroaIxane VelázquezHope JonesRoy D. FosterScott R. WhittemoreJorge D. Miranda. (2005) Upregulation of EphA3 Receptor after Spinal Cord Injury. Journal of Neurotrauma 22:8, pages 929-935.
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John Cobb & Denis Duboule. (2005) Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia. Development 132:13, pages 3055-3067.
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