36
Views
65
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Interleukin-3 Stimulation of mcl-1 Gene Transcription Involves Activation of the PU.1 Transcription Factor through a p38 Mitogen-Activated Protein Kinase-Dependent Pathway

, &
Pages 1896-1909 | Received 02 Aug 2002, Accepted 13 Dec 2002, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Adelaide IJ Young, Paul Timpson, David Gallego-Ortega, Christopher J. Ormandy & Samantha R. Oakes. (2018) Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion. Cell Adhesion & Migration 12:6, pages 513-523.
Read now
Hsuan Liu, Hsien-Wei Peng, Yi-Sheng Cheng, Hanna S. Yuan & Hsin-Fang Yang-Yen. (2005) Stabilization and Enhancement of the Antiapoptotic Activity of Mcl-1 by TCTP. Molecular and Cellular Biology 25:8, pages 3117-3126.
Read now

Articles from other publishers (63)

Shujing Li, Wanping Guo & Huijian Wu. (2021) The role of post-translational modifications in the regulation of MCL1. Cellular Signalling 81, pages 109933.
Crossref
Y. B. Balzhanova & V. G. Savchenko. (2020) The role of interleukin-3 and its receptor in acute leukemia pathogenesis. Russian journal of hematology and transfusiology 65:3, pages 335-350.
Crossref
Gemma L. Kelly & Andreas Strasser. (2020) Toward Targeting Antiapoptotic MCL-1 for Cancer Therapy. Annual Review of Cancer Biology 4:1, pages 299-313.
Crossref
Anna Kawiak, Anna Domachowska, Aleksandra Krolicka, Monika Smolarska & Ewa Lojkowska. (2019) 3-Chloroplumbagin Induces Cell Death in Breast Cancer Cells Through MAPK-Mediated Mcl-1 Inhibition. Frontiers in Pharmacology 10.
Crossref
Robert Ferguson, Alexi Archambault, Danny Simpson, Leah Morales, Vylyny Chat, Esther Kazlow, Rebecca Lax, Garrett Yoon, Una Moran, Richard Shapiro, Anna Pavlick, David Polsky, Iman Osman & Tomas Kirchhoff. (2019) Immunomodulatory germline variation associated with the development of multiple primary melanoma (MPM). Scientific Reports 9:1.
Crossref
Alyssa Carey, David K. EdwardsVV, Christopher A. Eide, Laura Newell, Elie Traer, Bruno C. Medeiros, Daniel A. Pollyea, Michael W. Deininger, Robert H. Collins, Jeffrey W. Tyner, Brian J. Druker, Grover C. Bagby, Shannon K. McWeeney & Anupriya Agarwal. (2017) Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia. Cell Reports 18:13, pages 3204-3218.
Crossref
J Cui & W J Placzek. (2016) PTBP1 modulation of MCL1 expression regulates cellular apoptosis induced by antitubulin chemotherapeutics. Cell Death & Differentiation 23:10, pages 1681-1690.
Crossref
Jiyun Lee, Soyeon Lim, Byeong-Wook Song, Min-Ji Cha, Onju Ham, Se-Yeon Lee, Changyoun Lee, Jun-Hee Park, Yoonjin Bae, Hyang-Hee Seo, Minji Seung, Eunhyun Choi & Ki-Chul Hwang. (2015) MicroRNA-29b Inhibits Migration and Proliferation of Vascular Smooth Muscle Cells in Neointimal Formation. Journal of Cellular Biochemistry 116:4, pages 598-608.
Crossref
Haidan Liu, Jinfu Yang, Yunchang Yuan, Zhenkun Xia, Mingjiu Chen, Li Xie, Xiaolong Ma, Jian Wang, Sufeng Ouyang, Qin Wu, Fenglei Yu, Xinmin Zhou, Yifeng Yang, Ya Cao, Jianguo Hu & Bangliang Yin. (2014) Regulation of Mcl-1 by constitutive activation of NF-kappaB contributes to cell viability in human esophageal squamous cell carcinoma cells. BMC Cancer 14:1.
Crossref
Boet van Riel & Frank Rosenbauer. (2014) Epigenetic control of hematopoiesis: the PU.1 chromatin connection. Biological Chemistry 395:11, pages 1265-1274.
Crossref
Akira Yoshida, Miyuki Ookura, Kouichi Zokumasu & Takanori Ueda. (2014) Gö6976, a FLT3 kinase inhibitor, exerts potent cytotoxic activity against acute leukemia via inhibition of survivin and MCL-1. Biochemical Pharmacology 90:1, pages 16-24.
Crossref
Tanapat Palaga, Siriluk Ratanabunyong, Thitiporn Pattarakankul, Naunpun Sangphech, Wipawee Wongchana, Yukihiro Hadae & Patipark Kueanjinda. (2013) Notch signaling regulates expression of Mcl-1 and apoptosis in PPD-treated macrophages. Cellular & Molecular Immunology 10:5, pages 444-452.
Crossref
Jeong-Eun Kwon, Bu-Yeon Kim, Seo-Young Kwak, In-Hwa Bae & Young-Hoon Han. (2013) Ionizing radiation-inducible microRNA miR-193a-3p induces apoptosis by directly targeting Mcl-1. Apoptosis 18:7, pages 896-909.
Crossref
Katrin M Jaedicke, Ashleigh Roythorne, Kay Padget, Stephen Todryk, Philip M Preshaw & John J Taylor. (2013) Leptin up-regulates TLR2 in human monocytes. Journal of Leukocyte Biology 93:4, pages 561-571.
Crossref
Kuen-Feng Chen, Hui-Ling Chen, Chung-Wai Shiau, Chun-Yu Liu, Pei-Yi Chu, Wei-Tien Tai, Kimihisa Ichikawa, Pei-Jer Chen & Ann-Lii Cheng. (2013) Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody. British Journal of Pharmacology 168:3, pages 658-672.
Crossref
L Dong, C C Jiang, R F Thorne, A Croft, F Yang, H Liu, C E de Bock, P Hersey & X D Zhang. (2011) Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress. Oncogene 30:34, pages 3716-3726.
Crossref
Ellen V. Rothenberg. (2011) T Cell Lineage Commitment: Identity and Renunciation. The Journal of Immunology 186:12, pages 6649-6655.
Crossref
Jere W. McBride & David H. Walker. (2011) Molecular and cellular pathobiology of Ehrlichia infection: targets for new therapeutics and immunomodulation strategies . Expert Reviews in Molecular Medicine 13.
Crossref
Yen-Chun Pan, Chien-Feng Li, Chiung-Yuan Ko, Min-Hsiung Pan, Pei-Jung Chen, Joseph T. Tseng, Wen-Chun Wu, Wen-Chang Chang, A-Mei Huang, Esta Sterneck & Ju-Ming Wang. (2010) CEBPD Reverses RB/E2F1-Mediated Gene Repression and Participates in HMDB-Induced Apoptosis of Cancer Cells. Clinical Cancer Research 16:23, pages 5770-5780.
Crossref
Chi-Ruei Huang & Hsin-Fang Yang-Yen. (2010) The fast-mobility isoform of mouse Mcl-1 is a mitochondrial matrix-localized protein with attenuated anti-apoptotic activity. FEBS Letters 584:15, pages 3323-3330.
Crossref
J K Son, S Varadarajan & S B Bratton. (2010) TRAIL-activated stress kinases suppress apoptosis through transcriptional upregulation of MCL-1. Cell Death & Differentiation 17:8, pages 1288-1301.
Crossref
Luke W. Thomas, Connie Lam & Steven W. Edwards. (2010) Mcl-1; the molecular regulation of protein function. FEBS Letters 584:14, pages 2981-2989.
Crossref
Martin Schwickart, XiaoDong Huang, Jennie R. Lill, Jinfeng Liu, Ronald Ferrando, Dorothy M. French, Heather Maecker, Karen O’Rourke, Fernando Bazan, Jeffrey Eastham-Anderson, Peng Yue, David Dornan, David C. S. Huang & Vishva M. Dixit. (2009) Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival. Nature 463:7277, pages 103-107.
Crossref
Céline Charlot, Hélène Dubois-Pot, Tsvetan Serchov, Yves Tourrette & Bohdan Wasylyk. 2010. Transcription Factors. Transcription Factors 3 30 .
Lenka Stixová, Jiřina Procházková, Karel Souček, Jiřina Hofmanová & Alois Kozubík. (2009) 5-Lipoxygenase inhibitors potentiate 1α,25-dihydroxyvitamin D3-induced monocytic differentiation by activating p38 MAPK pathway. Molecular and Cellular Biochemistry 330:1-2, pages 229-238.
Crossref
Amani Mankaï, Virginie Buhé, Mariam Hammadi, Pierre Youinou, Ibtissem Ghedira, Christian Berthou & Anne Bordron. (2009) Improvement of Rituximab Efficiency in Chronic Lymphocytic Leukemia by CpG-Mediated Upregulation of CD20 Expression Independently of PU.1. Annals of the New York Academy of Sciences 1173:1, pages 721-728.
Crossref
Myungsoo Joo, Minjae Kwon, Yong-Jig Cho, Ningning Hu, Tetyana V. Pedchenko, Ruxana T. Sadikot, Timothy S. Blackwell & John W. Christman. (2009) Lipopolysaccharide-dependent interaction between PU.1 and cJun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophages. American Journal of Physiology-Lung Cellular and Molecular Physiology 296:5, pages L771-L779.
Crossref
Chia-Yu Yang, Nai-Hui Lin, Jan-Mou Lee, Ching-Yu Huang, Hsiang-Ju Min, Jeffrey Jong-Young Yen, Nan-Shih Liao & Hsin-Fang Yang-Yen. (2009) Promoter Knock-In Mutations Reveal a Role of Mcl-1 in Thymocyte-Positive Selection and Tissue or Cell Lineage-Specific Regulation of Mcl-1 Expression. The Journal of Immunology 182:5, pages 2959-2968.
Crossref
Jian Cui, Ning Zhu, Qingyang Wang, Ming Yu, Jiannan Feng, Yan Li, Jiyan Zhang & Beifen Shen. (2009) p38 MAPK contributes to CD54 expression and the enhancement of phagocytic activity during macrophage development. Cellular Immunology 256:1-2, pages 6-11.
Crossref
Chen Chen Jiang, Keryn Lucas, Kelly A. Avery-Kiejda, Margaret Wade, Charles E. deBock, Rick F. Thorne, John Allen, Peter Hersey & Xu Dong Zhang. (2008) Up-regulation of Mcl-1 Is Critical for Survival of Human Melanoma Cells upon Endoplasmic Reticulum Stress. Cancer Research 68:16, pages 6708-6717.
Crossref
Dharmalingam Subramaniam, Gopalan Natarajan, Satish Ramalingam, Ilangovan Ramachandran, Randal May, Lurdes Queimado, Courtney W. Houchen & Shrikant Anant. (2008) Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2. American Journal of Physiology-Gastrointestinal and Liver Physiology 294:4, pages G1025-G1032.
Crossref
Anser C. Azim, Xuerong Wang, Gye Young Park, Ruxana T. Sadikot, Hongmei Cao, Biji Mathew, Michael Atchison, Richard B. van Breemen, Myungsoo Joo & John W. Christman. (2007) NF-κB-Inducing Kinase Regulates Cyclooxygenase 2 Gene Expression in Macrophages by Phosphorylation of PU.1. The Journal of Immunology 179:11, pages 7868-7875.
Crossref
Osvaldo Martinez, Charalampos Valmas & Christopher F. Basler. (2007) Ebola virus-like particle-induced activation of NF-κB and Erk signaling in human dendritic cells requires the glycoprotein mucin domain. Virology 364:2, pages 342-354.
Crossref
Shogo Kobayashi, Sun-Hee Lee, Xue W. Meng, Justin L. Mott, Steven F. Bronk, Nathan W. Werneburg, Ruth W. Craig, Scott H. Kaufmann & Gregory J. Gores. (2007) Serine 64 Phosphorylation Enhances the Antiapoptotic Function of Mcl-1. Journal of Biological Chemistry 282:25, pages 18407-18417.
Crossref
V. G. Tyazhelova. (2007) The role of the interaction between signaling protein domains and of the complexes of signaling proteins in apoptosis initiation. Biology Bulletin 34:2, pages 99-109.
Crossref
Leah DiMascio, Carlijn Voermans, Mweia Uqoezwa, Andrew Duncan, Danhong Lu, Judy Wu, Uma Sankar & Tannishtha Reya. (2007) Identification of Adiponectin as a Novel Hemopoietic Stem Cell Growth Factor. The Journal of Immunology 178:6, pages 3511-3520.
Crossref
Julie A. Vrana, Emily S. Cleaveland, Alan Eastman & Ruth W. Craig. (2006) Inducer-and cell type-specific regulation of antiapoptotic MCL1 in myeloid leukemia and multiple myeloma cells exposed to differentiation-inducing or microtubule-disrupting agents. Apoptosis 11:8, pages 1275-1288.
Crossref
S. A. Gross, J. H. Zheng, A. T. Le, P. J. Kerzic & R. D. Irons. (2006) PU.1 phosphorylation correlates with hydroquinone-induced alterations in myeloid differentiation and cytokine-dependent clonogenic response in human CD34+ hematopoietic progenitor cells. Cell Biology and Toxicology 22:4, pages 229-241.
Crossref
Michael D. Liang, Yue Zhang, Daniel McDevit, Sylvia Marecki & Barbara S. Nikolajczyk. (2006) The Interleukin-1β Gene Is Transcribed from a Poised Promoter Architecture in Monocytes. Journal of Biological Chemistry 281:14, pages 9227-9237.
Crossref
Hsin-Fang Yang-Yen. (2006) Mcl-1: a highly regulated cell death and survival controller. Journal of Biomedical Science 13:2, pages 201-204.
Crossref
S. Roy Himes, David P. Sester, Timothy Ravasi, Stephen L. Cronau, Tedjo Sasmono & David A. Hume. (2006) The JNK Are Important for Development and Survival of Macrophages. The Journal of Immunology 176:4, pages 2219-2228.
Crossref
Leonhard X. HeinzBarbara PlatzerPeter M. ReisnerAlmut JörglSabine TaschnerFlorian GöbelHerbert Strobl. (2006) Differential involvement of PU.1 and Id2 downstream of TGF-β1 during Langerhans-cell commitment. Blood 107:4, pages 1445-1453.
Crossref
Mark F van Delft & David CS Huang. (2006) How the Bcl-2 family of proteins interact to regulate apoptosis. Cell Research 16:2, pages 203-213.
Crossref
Jeffrey Jong‐Young Yen & Hsin‐Fang Yang‐Yen. 2006. Interleukins. Interleukins 147 163 .
Yuka KannoBen-Zion LeviTomohiko TamuraKeiko Ozato. (2005) Immune Cell-Specific Amplification of Interferon Signaling by the IRF-4/8-PU.1 Complex. Journal of Interferon & Cytokine Research 25:12, pages 770-779.
Crossref
Michelle B. Miranda, Hong Xu, James A. Torchia & Daniel E. Johnson. (2005) Cytokine-induced myeloid differentiation is dependent on activation of the MEK/ERK pathway. Leukemia Research 29:11, pages 1293-1306.
Crossref
Mohamed Rahmani, Eric Maynard Davis, Cheryl Bauer, Paul Dent & Steven Grant. (2005) Apoptosis Induced by the Kinase Inhibitor BAY 43-9006 in Human Leukemia Cells Involves Down-regulation of Mcl-1 through Inhibition of Translation. Journal of Biological Chemistry 280:42, pages 35217-35227.
Crossref
Fumiko Kihara-Negishi, Mitsuhiro Suzuki, Toshiyuki Yamada, Takuya Sakurai & Tsuneyuki Oikawa. (2005) Impaired repressor activity and biological functions of PU.1 in MEL cells induced by mutations in the acetylation motifs within the ETS domain. Biochemical and Biophysical Research Communications 335:2, pages 477-484.
Crossref
Yung-Luen Yu, Yun-Jung Chiang, Yu-Chun Chen, Michael Papetti, Chiun-Gung Juo, Arthur I. Skoultchi & Jeffrey J.Y. Yen. (2005) MAPK-mediated Phosphorylation of GATA-1 Promotes Bcl-X Expression and Cell Survival. Journal of Biological Chemistry 280:33, pages 29533-29542.
Crossref
Ju-Ming Wang, Joseph T. Tseng & Wen-Chang Chang. (2005) Induction of Human NF-IL6β by Epidermal Growth Factor Is Mediated through the p38 Signaling Pathway and cAMP Response Element-binding Protein Activation in A431 Cells. Molecular Biology of the Cell 16:7, pages 3365-3376.
Crossref
Karl J. AichbergerMatthias MayerhoferMaria-Theresa KrauthHans SkvaraStefan FlorianKaroline SonneckCahit AkgulSophia DerdakWinfried F. PicklVolker WacheckEdgar SelzerBrett P. MoniaRichard MorigglPeter ValentChristian Sillaber. (2005) Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides. Blood 105:8, pages 3303-3311.
Crossref
Ellen V. RothenbergTom Taghon. (2005) MOLECULAR GENETICS OF T CELL DEVELOPMENT. Annual Review of Immunology 23:1, pages 601-649.
Crossref
Christopher J. Dionne, Kevin Y. Tse, Angela H. Weiss, Christopher B. Franco, David L. Wiest, Michele K. Anderson & Ellen V. Rothenberg. (2005) Subversion of T lineage commitment by PU.1 in a clonal cell line system. Developmental Biology 280:2, pages 448-466.
Crossref
Hualin Zhong, Akiko Takeda, Reza Nazari, Helen Shio, Günter Blobel & Nabeel R. Yaseen. (2005) Carrier-independent Nuclear Import of the Transcription Factor PU.1 via RanGTP-stimulated Binding to Nup153. Journal of Biological Chemistry 280:11, pages 10675-10682.
Crossref
Tina L. Tootle & Ilaria Rebay. (2005) Post-translational modifications influence transcription factor activity: A view from the ETS superfamily. BioEssays 27:3, pages 285-298.
Crossref
Jennifer K Warner, Jean C Y Wang, Kristin J Hope, Liqing Jin & John E Dick. (2004) Concepts of human leukemic development. Oncogene 23:43, pages 7164-7177.
Crossref
Jeffrey J. Presneill, Koh Nakata, Yoshikazu Inoue & John F. Seymour. (2004) Pulmonary alveolar proteinosis. Clinics in Chest Medicine 25:3, pages 593-613.
Crossref
Chiharu Nishiyama, Nobutaka Masuoka, Makoto Nishiyama, Tomonobu Ito, Hisakazu Yamane, Ko Okumura & Hideoki Ogawa. (2004) Evidence against requirement of Ser41 and Ser45 for function of PU.1 - Molecular cloning of rat PU.1. FEBS Letters 572:1-3, pages 57-64.
Crossref
Myungsoo Joo, Gye Young Park, Jeffrey G. Wright, Timothy S. Blackwell, Michael L. Atchison & John W. Christman. (2004) Transcriptional Regulation of the Cyclooxygenase-2 Gene in Macrophages by PU.1. Journal of Biological Chemistry 279:8, pages 6658-6665.
Crossref
Mingqun Lin & Yasuko Rikihisa. (2004) Ehrlichia chaffeensis downregulates surface Toll-like receptors 2/4, CD14 and transcription factors PU.1 and inhibits lipopolysaccharide activation of NF-κB, ERK 1/2 and p38 MAPK in host monocytes . Cellular Microbiology 6:2, pages 175-186.
Crossref
U Testa, R Riccioni, D Diverio, A Rossini, F Lo Coco & C Peschle. (2003) Interleukin-3 receptor in acute leukemia. Leukemia 18:2, pages 219-226.
Crossref
Satoshi Hirose, Hirofumi Nishizumi & Hitoshi Sakano. (2003) Pub, a novel PU.1 binding protein, regulates the transcriptional activity of PU.1. Biochemical and Biophysical Research Communications 311:2, pages 351-360.
Crossref
Shen-Hsi Yang, Andrew D. Sharrocks & Alan J. Whitmarsh. (2003) Transcriptional regulation by the MAP kinase signaling cascades. Gene 320, pages 3-21.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.