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DNA Dynamics and Chromosome Structure

p53 Binding Protein 53BP1 Is Required for DNA Damage Responses and Tumor Suppression in Mice

Irene M. Ward1 Departments of Oncology
,
Kay Minn1 Departments of Oncology
,
Jan van Deursen2 Pediatric and Adolescent Medicine, Mayo Clinic and Foundation, Rochester, Minnesota55905
&
Junjie Chen1 Departments of OncologyCorrespondence[email protected]
Pages 2556-2563 | Received 19 Nov 2002, Accepted 07 Jan 2003, Published online: 27 Mar 2023

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Cynthia L. Innes, Jill E. Hesse, Abigail J. Morales, Beth A. Helmink, Shepherd H. Schurman, Barry P. Sleckman & Richard S. Paules. (2020) DNA damage responses in murine Pre-B cells with genetic deficiencies in damage response genes. Cell Cycle 19:1, pages 67-83.
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Philip A. Knobel, Rimma Belotserkovskaya, Yaron Galanty, Christine K. Schmidt, Stephen P. Jackson & Travis H. Stracker. (2014) USP28 Is Recruited to Sites of DNA Damage by the Tandem BRCT Domains of 53BP1 but Plays a Minor Role in Double-Strand Break Metabolism. Molecular and Cellular Biology 34:11, pages 2062-2074.
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Monica Croke, Martin A Neumann, David A Grotsky, Ray Kreienkamp, Sree C Yaddanapudi & Susana Gonzalo. (2013) Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells. Cell Cycle 12:23, pages 3629-3639.
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Yi-Bo Luo, Jun-Yu Ma, Qing-Hua Zhang, Fei Lin, Zhong-Wei Wang, Lin Huang, Heide Schatten & Qing-Yuan Sun. (2013) MBTD1 is associated with Pr-Set7 to stabilize H4K20me1 in mouse oocyte meiotic maturation. Cell Cycle 12:7, pages 1142-1150.
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Benjamin Orsburn, Beatriz Escudero, Mansi Prakash, Silvia Gesheva, Guosheng Liu, David L. Huso & Sonia Franco. (2010) Differential Requirement for H2AX and 53BP1 in Organismal Development and Genome Maintenance in the Absence of Poly(ADP)ribosyl Polymerase 1. Molecular and Cellular Biology 30:10, pages 2341-2352.
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Francesco Marchetti, Matthew A. Coleman, Irene M. Jones & Andrew J. Wyrobek. (2006) Candidate protein biodosimeters of human exposure to ionizing radiation. International Journal of Radiation Biology 82:9, pages 605-639.
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Irene M. Ward, Simone Difilippantonio, Kay Minn, Melissa D. Mueller, Julian R. Molina, Xiaochun Yu, Craig S. Frisk, Thomas Ried, Andre Nussenzweig & Junjie Chen. (2005) 53BP1 Cooperates with p53 and Functions as a Haploinsufficient Tumor Suppressor in Mice. Molecular and Cellular Biology 25:22, pages 10079-10086.
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David J. Adams, Louise van der Weyden, Fanni V. Gergely, Mark J. Arends, Bee Ling Ng, David Tannahill, Roland Kanaar, Andrea Markus, Brian J. Morris & Allan Bradley. (2005) BRCTx Is a Novel, Highly Conserved RAD18-Interacting Protein. Molecular and Cellular Biology 25:2, pages 779-788.
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