Citations (153)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (10)
Apala Pal, Pritam Kumar Ghosh & Saumitra Das. (2023) The “LINC” between Δ40p53-miRNA Axis in the Regulation of Cellular Homeostasis. Molecular and Cellular Biology 43:7, pages 335-353.
Read now
Read now
Aanchal Katoch, Sachin Kumar Tripathi, Apala Pal & Saumitra Das. (2021) Regulation of miR-186-YY1 axis by the p53 translational isoform ∆40p53: implications in cell proliferation. Cell Cycle 20:5-6, pages 561-574.
Read now
Read now
Liam Hayman, Wajeeh Raza Chaudhry, Victor V. Revin, Nikolai Zhelev & Jean-Christophe Bourdon. (2019) What is the potential of p53 isoforms as a predictive biomarker in the treatment of cancer?. Expert Review of Molecular Diagnostics 19:2, pages 149-159.
Read now
Read now
Sylvanie Surget, Marie P Khoury & Jean-Christophe Bourdon. (2014) Uncovering the role of p53 splice variants in human malignancy: a clinical perspective. OncoTargets and Therapy 7, pages 57-68.
Read now
Read now
Agnieszka Górska, Leszek Błaszczyk, Mariola Dutkiewicz & Jerzy Ciesiołka. (2013) Length variants of the 5′ untranslated region of p53 mRNA and their impact on the efficiency of translation initiation of p53 and its N-truncated isoform ΔNp53. RNA Biology 10:11, pages 1726-1740.
Read now
Read now
Jianhua Hu & Xuming He. (2012) Searching for Alternative Splicing With a Joint Model on Probe Measurability and Expression Intensities. Journal of the American Statistical Association 107:499, pages 935-945.
Read now
Read now
Jianhua Hu, Xuming He, Gilbert J. Cote & Ralf Krahe. (2009) Singular Value Decomposition–Based Alternative Splicing Detection. Journal of the American Statistical Association 104:487, pages 944-953.
Read now
Read now
Alberto Valbuena, Francisco M. Vega, Sandra Blanco & Pedro A. Lazo. (2006) p53 Downregulates Its Activating Vaccinia-Related Kinase 1, Forming a New Autoregulatory Loop. Molecular and Cellular Biology 26:13, pages 4782-4793.
Read now
Read now
Øystein Bruserud, Camilla Stapnes, Karl Johan Tronstad, Anita Ryningen, Nina Ånensen & Bjørn Tore Gjertsen. (2006) Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML. Expert Opinion on Therapeutic Targets 10:1, pages 51-68.
Read now
Read now
Kelly Lynn Harms & Xinbin Chen. (2005) The C Terminus of p53 Family Proteins Is a Cell Fate Determinant. Molecular and Cellular Biology 25:5, pages 2014-2030.
Read now
Read now
Articles from other publishers (143)
Meiyu Qu, Qiangqiang He, Jiahao Luo, Tingyu Shen, Ruibo Gao, Yana Xu, Chengyun Xu, Muhammad Qasim Barkat, Ling-Hui Zeng & Ximei Wu. (2023) Sonic hedgehog signaling: Alternative splicing and pathogenic role in medulloblastoma. Genes & Diseases 10:5, pages 2013-2028.
Crossref
Crossref
Luiza Steffens Reinhardt, Kira Groen, Cheryl Newton & Kelly A. Avery-Kiejda. (2023) The role of truncated p53 isoforms in the DNA damage response. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1878:3, pages 188882.
Crossref
Crossref
Mevan Jacksi, Eva Schad, László Buday & Agnes Tantos. (2023) Absence of Scaffold Protein Tks4 Disrupts Several Signaling Pathways in Colon Cancer Cells. International Journal of Molecular Sciences 24:2, pages 1310.
Crossref
Crossref
Luiza Steffens Reinhardt, Xiajie Zhang, Kira Groen, Brianna C. Morten, Geoffry N. De Iuliis, Antony W. Braithwaite, Jean-Christophe Bourdon & Kelly A. Avery-Kiejda. (2022) Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage. Cell Death & Disease 13:10.
Crossref
Crossref
Joanna Szpotkowska, Kamil Szpotkowski & Jerzy Ciesiołka. (2022) Structural Characteristics of the 5′-Terminal Region of Mouse p53 mRNA and Identification of Proteins That Bind to This mRNA Region. International Journal of Molecular Sciences 23:17, pages 9709.
Crossref
Crossref
Muyang Li, Fredrick Philantrope, Alexandra Diot, Jean-Christophe Bourdon & Patricia Thompson. (2022) A Novel Role of SMG1 in Cholesterol Homeostasis That Depends Partially on p53 Alternative Splicing. Cancers 14:13, pages 3255.
Crossref
Crossref
Liuqun Zhao & Suparna Sanyal. (2022) p53 Isoforms as Cancer Biomarkers and Therapeutic Targets. Cancers 14:13, pages 3145.
Crossref
Crossref
Luiza Steffens Reinhardt, Kira Groen, Brianna C. Morten, Jean-Christophe Bourdon & Kelly A. Avery-Kiejda. (2022) Cytoplasmic p53β Isoforms Are Associated with Worse Disease-Free Survival in Breast Cancer. International Journal of Molecular Sciences 23:12, pages 6670.
Crossref
Crossref
Verónica Antonio-Véjar, Elizabeth Ortiz-Sánchez, Pedro Rosendo-Chalma, Carlos C. Patiño-Morales, Miriam C. Guido-Jiménez, Eduardo Alvarado-Ortiz, Greco Hernández & Alejandro García-Carrancá. (2022) New insights into the interactions of HPV-16 E6*I and E6*II with p53 isoforms and induction of apoptosis in cancer-derived cell lines. Pathology - Research and Practice 234, pages 153890.
Crossref
Crossref
Ying Liu, Guangwei Ma, Zenghong Gao, Jian Li, Jin Wang, Xiangping Zhu, Ruowu Ma, Jiawen Yang, Yiting Zhou, Kaishun Hu, Yin Zhang & Yabin Guo. (2022) Global chromosome rearrangement induced by CRISPR-Cas9 reshapes the genome and transcriptome of human cells. Nucleic Acids Research 50:6, pages 3456-3474.
Crossref
Crossref
Xiajie Zhang, Kira Groen, Brianna C. Morten, Luiza Steffens Reinhardt, Hamish G. Campbell, Antony W. Braithwaite, Jean‐Christophe Bourdon & Kelly A. Avery‐Kiejda. (2021) Effect of p53 and its N‐terminally truncated isoform, Δ40p53, on breast cancer migration and invasion. Molecular Oncology 16:2, pages 447-465.
Crossref
Crossref
Sushil K. Jaiswal, Sonam Raj & Melvin L. DePamphilis. (2021) Developmental Acquisition of p53 Functions. Genes 12:11, pages 1675.
Crossref
Crossref
Stephen Among James, Hui San Ong, Ranjeev Hari & Asif M. Khan. (2021) A systematic bioinformatics approach for large-scale identification and characterization of host-pathogen shared sequences. BMC Genomics 22:S3.
Crossref
Crossref
Yan SunAmbroise Manceau, Lisa FrydmanLucie CappuccioDavid Neves, Valeria BassoHong WangJoanna FombonneCarine MaissePatrick MehlenAndrea Paradisi. (2021) Δ40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity. Proceedings of the National Academy of Sciences 118:36.
Crossref
Crossref
Brittany Lynn Angarola & Olga Anczuków. (2021) Splicing alterations in healthy aging and disease. WIREs RNA 12:4.
Crossref
Crossref
Anđela Horvat, Ana Tadijan, Ignacija Vlašić & Neda Slade. (2021) p53/p73 Protein Network in Colorectal Cancer and Other Human Malignancies. Cancers 13:12, pages 2885.
Crossref
Crossref
Annette Lasham, Nicholas Knowlton, Sunali Y. Mehta, Antony W. Braithwaite & Cristin G. Print. (2021) Breast Cancer Patient Prognosis Is Determined by the Interplay between TP53 Mutation and Alternative Transcript Expression: Insights from TP53 Long Amplicon Digital PCR Assays. Cancers 13:7, pages 1531.
Crossref
Crossref
Anne H. Moxley & David Reisman. (2020) Context is key: Understanding the regulation, functional control, and activities of the p53 tumour suppressor. Cell Biochemistry and Function 39:2, pages 235-247.
Crossref
Crossref
Jolanda Magri, Alessandro Gasparetto, Laura Conti, Enzo Calautti, Chiara Cossu, Roberto Ruiu, Giuseppina Barutello & Federica Cavallo. (2021) Tumor-Associated Antigen xCT and Mutant-p53 as Molecular Targets for New Combinatorial Antitumor Strategies. Cells 10:1, pages 108.
Crossref
Crossref
Brehima Diakite, Yaya Kassogue, Guimogo Dolo, Oumar Kassogue, Mamadou Lassine Keita, Brian Joyce, Erin Neuschler, Jun Wang, Jonah Musa, Cheick Bougari Traore, Bakarou Kamate, Etienne Dembele, Sellama Nadifi, Mercy Isichei, Jane L. Holl, Robert Murphy, Seydou Doumbia, Lifang Hou & Mamoudou Maiga. (2020) Association of PIN3 16-bp duplication polymorphism of TP53 with breast cancer risk in Mali and a meta-analysis. BMC Medical Genetics 21:1.
Crossref
Crossref
Surinder M. Soond, Maria V. Kozhevnikova, Paul A. Townsend & Andrey A. ZamyatninJr.Jr.. (2020) Integrative p53, micro-RNA and Cathepsin Protease Co-Regulatory Expression Networks in Cancer. Cancers 12:11, pages 3454.
Crossref
Crossref
Luiza Steffens Reinhardt, Xiajie Zhang, Anna Wawruszak, Kira Groen, Geoffry N. De Iuliis & Kelly A. Avery-Kiejda. (2020) Good Cop, Bad Cop: Defining the Roles of Δ40p53 in Cancer and Aging. Cancers 12:6, pages 1659.
Crossref
Crossref
Shan-Ju Yeh, Shuo-Wei Chen & Bor-Sen Chen. (2020) Investigation of the Genome-Wide Genetic and Epigenetic Networks for Drug Discovery Based on Systems Biology Approaches in Colorectal Cancer. Frontiers in Genetics 11.
Crossref
Crossref
Aleli Campbell, Jonathon E. Mohl, Denisse A. Gutierrez, Armando Varela-Ramirez & Thomas Boland. (2020) Thermal Bioprinting Causes Ample Alterations of Expression of LUCAT1, IL6, CCL26, and NRN1L Genes and Massive Phosphorylation of Critical Oncogenic Drug Resistance Pathways in Breast Cancer Cells. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Crossref
Leïla T. S. Fusée, Mónica Marín, Robin Fåhraeus & Ignacio López. (2020) Alternative Mechanisms of p53 Action During the Unfolded Protein Response. Cancers 12:2, pages 401.
Crossref
Crossref
Shiori Suzuki, Shuichi Tsutsumi, Yu Chen, Chikako Ozeki, Atsushi Okabe, Tatsuya Kawase, Hiroyuki Aburatani & Rieko Ohki. (2020) Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain. Cancer Science 111:2, pages 451-466.
Crossref
Crossref
Ruizhi Wang, Md. Faruk Hossain, Jovan Mirkovic, Samuel Sabzanov & Matteo Ruggiu. 2020. Immune Mediators in Cancer. Immune Mediators in Cancer
241
258
.
Otília Porubiaková, Natália Bohálová, Alberto Inga, Natália Vadovičová, Jan Coufal, Miroslav Fojta & Václav Brázda. (2019) The Influence of Quadruplex Structure in Proximity to P53 Target Sequences on the Transactivation Potential of P53 Alpha Isoforms. International Journal of Molecular Sciences 21:1, pages 127.
Crossref
Crossref
Kaori Fujita. (2019) p53 Isoforms in Cellular Senescence- and Ageing-Associated Biological and Physiological Functions. International Journal of Molecular Sciences 20:23, pages 6023.
Crossref
Crossref
Natalia Bartys, Ryszard Kierzek & Jolanta Lisowiec-Wachnicka. (2019) The regulation properties of RNA secondary structure in alternative splicing. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862:11-12, pages 194401.
Crossref
Crossref
Alice O. Coomer, Fiona Black, Alastair Greystoke, Jennifer Munkley & David J. Elliott. (2019) Alternative splicing in lung cancer. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862:11-12, pages 194388.
Crossref
Crossref
S. N. Naryzhny & O. K. Legina. (2019) Structural-Functional Diversity of p53 Proteoforms. Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry 13:4, pages 293-307.
Crossref
Crossref
Marijana Knezović Florijan, Petar Ozretić, Maro Bujak, Laura Pezzè, Yari Ciribilli, Željko Kaštelan, Neda Slade & Tvrtko Hudolin. (2019) The role of p53 isoforms’ expression and p53 mutation status in renal cell cancer prognosis. Urologic Oncology: Seminars and Original Investigations 37:9, pages 578.e1-578.e10.
Crossref
Crossref
Zhenping Chen, Paul J. Boor, Celeste C. Finnerty, David N. Herndon & Thomas Albrecht. (2019) Calpain-mediated cleavage of p53 in human cytomegalovirus-infected lung fibroblasts. FASEB BioAdvances 1:3, pages 151-166.
Crossref
Crossref
Sebastian Brachtendorf, Ruth Anna Wanger, Kerstin Birod, Dominique Thomas, Sandra Trautmann, Marthe-Susanna Wegner, Dominik C. Fuhrmann, Bernhard Brüne, Gerd Geisslinger & Sabine Grösch. (2018) Chemosensitivity of human colon cancer cells is influenced by a p53-dependent enhancement of ceramide synthase 5 and induction of autophagy. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1863:10, pages 1214-1227.
Crossref
Crossref
Baochen Zhu, Wantong Zhang, Yang Lu, Shaonan Hu, Rui Gao, Zongxi Sun, Xiaonan Chen, Junming Ma, Shuang Guo, Shouying Du & Pengyue Li. (2018) Network pharmacology-based identification of protective mechanism of Panax Notoginseng Saponins on aspirin induced gastrointestinal injury. Biomedicine & Pharmacotherapy 105, pages 159-166.
Crossref
Crossref
Yixia Wang, Yanchao Han, Pengfei Xu, Shihui Ding, Guangyuan Li, Hongbin Jin, Yaping Meng, Anming Meng & Shunji Jia. (2018) prpf4 is essential for cell survival and posterior lateral line primordium migration in zebrafish. Journal of Genetics and Genomics 45:8, pages 443-453.
Crossref
Crossref
Haiyang Zhang, Yong Zhao, Peng Sun, Miaoqing Zhao, Zhenhui Su, Xunbo Jin & Wei Song. (2018) p53β: a new prognostic marker for patients with clear-cell renal cell carcinoma from 5.3 years of median follow-up. Carcinogenesis 39:3, pages 368-374.
Crossref
Crossref
Hilla Solomon, Bastian Bräuning, Irit Fainer, Gili Ben-Nissan, Stav Rabani, Naomi Goldfinger, Oren Moscovitz, Zippora Shakked, Varda Rotter & Michal Sharon. (2017) Post-translational regulation of p53 function through 20S proteasome-mediated cleavage. Cell Death & Differentiation 24:12, pages 2187-2198.
Crossref
Crossref
Huizhi Guo, Xiaozhe Fu, Qiang Lin, Lihui Liu, Hongru Liang, Zhibin Huang, Ningqiu Li & Jianguo Su. (2017) Mandarin fish p53: Genomic structure, alternatively spliced variant and its mRNA expression after virus challenge. Fish & Shellfish Immunology 70, pages 536-544.
Crossref
Crossref
Mathieu Deschênes & Benoit Chabot. (2017) The emerging role of alternative splicing in senescence and aging. Aging Cell 16:5, pages 918-933.
Crossref
Crossref
Ignacio López, Anne-Sophie Tournillon, Rodrigo Prado Martins, Konstantinos Karakostis, Laurence Malbert-Colas, Karin Nylander & Robin Fåhraeus. (2017) p53-mediated suppression of BiP triggers BIK-induced apoptosis during prolonged endoplasmic reticulum stress. Cell Death & Differentiation 24:10, pages 1717-1729.
Crossref
Crossref
Yunjin Zang, Ying Shi, Kai Liu, Luxin Qiao, Xianghua Guo & Dexi Chen. (2017) Δ40p53 is involved in the inactivation of autophagy and contributes to inhibition of cell death in HCT116-Δ40p53 cells. Oncotarget 8:8, pages 12754-12763.
Crossref
Crossref
Kai Liu, Yunjin Zang, Xianghua Guo, Feili Wei, Jiming Yin, Lijun Pang & Dexi Chen. (2017) The Δ133p53 Isoform Reduces Wtp53-induced Stimulation of DNA Pol γ Activity in the Presence and Absence of D4T. Aging and disease 8:2, pages 228.
Crossref
Crossref
Wei Zhao, Katherine A. Hoadley, Joel S. Parker & Charles M. Perou. (2016) Identification of mRNA isoform switching in breast cancer. BMC Genomics 17:1.
Crossref
Crossref
Brianna C. Morten, Rodney J. Scott & Kelly A. Avery-Kiejda. (2016) Comparison of the QuantiGene 2.0 Assay and Real-Time RT-PCR in the Detection of p53 Isoform mRNA Expression in Formalin-Fixed Paraffin-Embedded Tissues- A Preliminary Study. PLOS ONE 11:11, pages e0165930.
Crossref
Crossref
Arnold J. Levine, Anna M. Puzio-Kuter, Chang S. Chan & Pierre Hainaut. (2016) The Role of the p53 Protein in Stem-Cell Biology and Epigenetic Regulation. Cold Spring Harbor Perspectives in Medicine 6:9, pages a026153.
Crossref
Crossref
Rasheena Edmondson, Audrey F. Adcock & Liju Yang. (2016) Influence of Matrices on 3D-Cultured Prostate Cancer Cells' Drug Response and Expression of Drug-Action Associated Proteins. PLOS ONE 11:6, pages e0158116.
Crossref
Crossref
Huey-Huey Chua, Chiun-Sheng Huang, Pei-Lun Weng & Te-Huei Yeh. (2016) TSGΔ154-1054 splice variant increases TSG101 oncogenicity by inhibiting its E3-ligase-mediated proteasomal degradation. Oncotarget 7:7, pages 8240-8252.
Crossref
Crossref
Brianna C. Morten, Michelle W. Wong-Brown, Rodney J. Scott & Kelly A. Avery-Kiejda. (2016)
The presence of the intron 3 16 bp duplication polymorphism of
p53
(rs17878362) in breast cancer is associated with a low Δ40p53:p53 ratio and better outcome
. Carcinogenesis 37:1, pages 81-86.
Crossref
Crossref
B Zhang, M Rotelli, M Dixon & B R Calvi. (2015) The function of Drosophila p53 isoforms in apoptosis. Cell Death & Differentiation 22:12, pages 2058-2067.
Crossref
Crossref
Beng Hooi PhangRashidah OthmanGaelle BougeardRen Hui ChiaThierry FrebourgChoong Leong TangPeh Yean CheahKanaga Sabapathy. (2015) Amino-terminal p53 mutations lead to expression of apoptosis proficient p47 and prognosticate better survival, but predispose to tumorigenesis. Proceedings of the National Academy of Sciences 112:46.
Crossref
Crossref
Mi Li, Mariana Pehar, Yan Liu, Anita Bhattacharyya, Su-Chun Zhang, Kenneth J. O'Riordan, Corinna Burger, Luciano D'Adamio & Luigi Puglielli. (2015) The amyloid precursor protein (APP) intracellular domain regulates translation of p44, a short isoform of p53, through an IRES-dependent mechanism. Neurobiology of Aging 36:10, pages 2725-2736.
Crossref
Crossref
Naoya Tatsumi, Nozomi Hojo, Hiroyuki Sakamoto, Rena Inaba, Nahoko Moriguchi, Keiko Matsuno, Mari Fukuda, Akihide Matsumura, Seiji Hayashi, Soyoko Morimoto, Jun Nakata, Fumihiro Fujiki, Sumiyuki Nishida, Hiroko Nakajima, Akihiro Tsuboi, Yoshihiro Oka, Naoki Hosen, Haruo Sugiyama & Yusuke Oji. (2015) Identification of a Novel C-Terminal Truncated WT1 Isoform with Antagonistic Effects against Major WT1 Isoforms. PLOS ONE 10:6, pages e0130578.
Crossref
Crossref
J Chen & W A Weiss. (2014) Alternative splicing in cancer: implications for biology and therapy. Oncogene 34:1, pages 1-14.
Crossref
Crossref
Effat Behravan & Mitra Asgharian Rezaee. 2015. Basic and Clinical Toxicology of Mustard Compounds. Basic and Clinical Toxicology of Mustard Compounds
317
347
.
James Yi-Hsin Chan, Ying-Chuan Chen, Shu-Ting Liu, Wei-Yuan Chou, Ching-Liang Ho & Shih-Ming Huang. (2014) Characterization of a new mouse p53 variant: loss-of-function and gain-of-function. Journal of Biomedical Science 21:1.
Crossref
Crossref
L. Perriaud, V. Marcel, C. Sagne, V. Favaudon, A. Guedin, A. De Rache, C. Guetta, F. Hamon, M.-P. Teulade-Fichou, P. Hainaut, J.-L. Mergny & J. Hall. (2014) Impact of G-quadruplex structures and intronic polymorphisms rs17878362 and rs1642785 on basal and ionizing radiation-induced expression of alternative p53 transcripts. Carcinogenesis 35:12, pages 2706-2715.
Crossref
Crossref
Yuen Ngan Fan, Daniel Meley, Barry Pizer & Violaine Sée. (2014) Mir-34a Mimics Are Potential Therapeutic Agents for p53-Mutated and Chemo-Resistant Brain Tumour Cells. PLoS ONE 9:9, pages e108514.
Crossref
Crossref
Mariana Pehar, Mi Hee Ko, Mi Li, Heidi Scrable & Luigi Puglielli. (2014) P44, the ‘longevity‐assurance’ isoform of P53, regulates tau phosphorylation and is activated in an age‐dependent fashion. Aging Cell 13:3, pages 449-456.
Crossref
Crossref
Thierry Soussi, Bernard Leroy & Peter E.M. Taschner. (2014)
Recommendations for Analyzing and Reporting
TP53
Gene Variants in the High-Throughput Sequencing Era
. Human Mutation 35:6, pages 766-778.
Crossref
Crossref
C. Sagne, V. Marcel, M. Bota, G. Martel-Planche, A. Nobrega, E. I. Palmero, L. Perriaud, M. Boniol, S. Vagner, D. G. Cox, C. S. Chan, J.-L. Mergny, M. Olivier, P. Ashton-Prolla, J. Hall, P. Hainaut & M. I. Achatz. (2013) Age at cancer onset in germline TP53 mutation carriers: association with polymorphisms in predicted G-quadruplex structures. Carcinogenesis 35:4, pages 807-815.
Crossref
Crossref
Kelly A. Avery-Kiejda, Brianna Morten, Michelle W. Wong-Brown, Andrea Mathe & Rodney J. Scott. (2014) The relative mRNA expression of p53 isoforms in breast cancer is associated with clinical features and outcome. Carcinogenesis 35:3, pages 586-596.
Crossref
Crossref
Rie Takahashi, Svetomir N. Markovic & Heidi J. Scrable. (2014) Dominant Effects of Δ40p53 on p53 Function and Melanoma Cell Fate. Journal of Investigative Dermatology 134:3, pages 791-800.
Crossref
Crossref
Zorka Milićević, Vladan Bajić, Lada Živković, Jelena Kasapović, Uroš Andjelković & Biljana Spremo-Potparević. (2014) Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells. The Scientific World Journal 2014, pages 1-10.
Crossref
Crossref
Hind Hafsi, Daniela Santos-Silva, Stéphanie Courtois-Cox & Pierre Hainaut. (2013) Effects of Δ40p53, an isoform of p53 lacking the N-terminus, on transactivation capacity of the tumor suppressor protein p53. BMC Cancer 13:1.
Crossref
Crossref
R Takahashi, C Giannini, J N Sarkaria, M Schroeder, J Rogers, D Mastroeni & H Scrable. (2012) p53 isoform profiling in glioblastoma and injured brain. Oncogene 32:26, pages 3165-3174.
Crossref
Crossref
Jeyanthy Eswaran, Anelia Horvath, Sucheta Godbole, Sirigiri Divijendra Reddy, Prakriti Mudvari, Kazufumi Ohshiro, Dinesh Cyanam, Sujit Nair, Suzanne A. W. Fuqua, Kornelia Polyak, Liliana D. Florea & Rakesh Kumar. (2013) RNA sequencing of cancer reveals novel splicing alterations. Scientific Reports 3:1.
Crossref
Crossref
A. Zoric, A. Horvat & N. Slade. (2012) Differential effects of diverse p53 isoforms on TAp73 transcriptional activity and apoptosis. Carcinogenesis 34:3, pages 522-529.
Crossref
Crossref
C Sagne, V Marcel, A Amadou, P Hainaut, M Olivier & J Hall. (2013) A meta-analysis of cancer risk associated with the TP53 intron 3 duplication polymorphism (rs17878362): geographic and tumor-specific effects. Cell Death & Disease 4:2, pages e492-e492.
Crossref
Crossref
Frédérique Végran, Magali Rebucci, Sandy Chevrier, Muriel Cadouot, Romain Boidot & Sarab Lizard-Nacol. (2013) Only Missense Mutations Affecting the DNA Binding Domain of P53 Influence Outcomes in Patients with Breast Carcinoma. PLoS ONE 8:1, pages e55103.
Crossref
Crossref
Yingjuan Qian & Xinbin Chen. 2013. Cell Senescence. Cell Senescence
37
61
.
Marie P. Khoury, Virginie Marcel, Kenneth Fernandes, Alexandra Diot, David P. Lane & Jean-Christophe Bourdon. 2013. p53 Protocols. p53 Protocols
1
14
.
Diana Vetter, Michal Cohen-Naftaly, Augusto Villanueva, Youngmin A. Lee, Peri Kocabayoglu, Rebekka Hannivoort, Goutham Narla, Josep M. Llovet, Swan N. Thung & Scott L. Friedman. (2012) Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing. Hepatology 56:4, pages 1361-1370.
Crossref
Crossref
Min Yang, Jack Wu, Si-hung Wu, An-ding Bi & D. Joshua Liao. (2012) Splicing of mouse p53 pre-mRNA does not always follow the “first come, first served” principle and may be influenced by cisplatin treatment and serum starvation. Molecular Biology Reports 39:9, pages 9247-9256.
Crossref
Crossref
Setsuko K Chambers & Jesse D Martinez. (2012) The significance of p53 isoform expression in serous ovarian cancer. Future Oncology 8:6, pages 683-686.
Crossref
Crossref
Emanuela Zaharieva, J. Kevin Chipman & Matthias Soller. (2012) Alternative splicing interference by xenobiotics. Toxicology 296:1-3, pages 1-12.
Crossref
Crossref
Zijun Y. Xu-MonetteL. Jeffrey MedeirosYong LiRobert Z. Orlowski, Michael Andreeff, Carlos E. Bueso-RamosTimothy C. Greiner, Timothy J. McDonnellKen H. Young. (2012) Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies. Blood 119:16, pages 3668-3683.
Crossref
Crossref
W Ma, Y Lin, W Xuan, P L Iversen, L J Smith & S Benchimol. (2011) Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs. Oncogene 31:8, pages 1024-1033.
Crossref
Crossref
V Marcel, M-L Dichtel-Danjoy, C Sagne, H Hafsi, D Ma, S Ortiz-Cuaran, M Olivier, J Hall, B Mollereau, P Hainaut & J-C Bourdon. (2011) Biological functions of p53 isoforms through evolution: lessons from animal and cellular models. Cell Death & Differentiation 18:12, pages 1815-1824.
Crossref
Crossref
Elianna M. Amin, Sebastian Oltean, Jing Hua, Melissa V.R. Gammons, Maryam Hamdollah-Zadeh, Gavin I. Welsh, Man-Kim Cheung, Lan Ni, Satoru Kase, Emma S. Rennel, Kirsty E. Symonds, Dawid G. Nowak, Brigitte Royer-Pokora, Moin A. Saleem, Masatoshi Hagiwara, Valérie A. Schumacher, Steven J. Harper, David R. Hinton, David O. Bates & Michael R. Ladomery. (2011) WT1 Mutants Reveal SRPK1 to Be a Downstream Angiogenesis Target by Altering VEGF Splicing. Cancer Cell 20:6, pages 768-780.
Crossref
Crossref
G Hofstetter, A Berger, E Schuster, A Wolf, G Hager, I Vergote, I Cadron, J Sehouli, E I Braicu, S Mahner, P Speiser, C Marth, A G Zeimet, H Ulmer, R Zeillinger & N Concin. (2011) Δ133p53 is an independent prognostic marker in p53 mutant advanced serous ovarian cancer. British Journal of Cancer 105:10, pages 1593-1599.
Crossref
Crossref
Hind HafsiPierre Hainaut. (2011) Redox Control and Interplay Between p53 Isoforms: Roles in the Regulation of Basal p53 Levels, Cell Fate, and Senescence. Antioxidants & Redox Signaling 15:6, pages 1655-1667.
Crossref
Crossref
Naoko Okumura, Hitomi Yoshida, Yasuko Kitagishi, Yuri Nishimura & Satoru Matsuda. (2011) Alternative splicings on p53, BRCA1 and PTEN genes involved in breast cancer. Biochemical and Biophysical Research Communications 413:3, pages 395-399.
Crossref
Crossref
Leszek Błaszczyk & Jerzy Ciesiołka. (2011) Secondary Structure and the Role in Translation Initiation of the 5′-Terminal Region of p53 mRNA. Biochemistry 50:33, pages 7080-7092.
Crossref
Crossref
Kyung-Sun Heo, Hakjoo Lee, Patrizia Nigro, Tamlyn Thomas, Nhat-Tu Le, Eugene Chang, Carolyn McClain, Cynthia A. Reinhart-King, Michael R. King, Bradford C. Berk, Keigi Fujiwara, Chang-Hoon Woo & Jun-ichi Abe. (2011) PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation. Journal of Cell Biology 193:5, pages 867-884.
Crossref
Crossref
Tania L. SlatterNoelyn HungHamish Campbell, Carina Rubio, Reena Mehta, Prudence RenshawGail WilliamsMichelle Wilson, Afra Engelmann, Aaron JeffsJanice A. RoydsMargaret A. Baird & Antony W. Braithwaite. (2011) Hyperproliferation, cancer, and inflammation in mice expressing a Δ133p53-like isoform. Blood 117:19, pages 5166-5177.
Crossref
Crossref
J P M Melis, E M Hoogervorst, C T M van Oostrom, E Zwart, T M Breit, J L A Pennings, A de Vries & H van Steeg. (2010) Genotoxic exposure: novel cause of selection for a functional ΔN-p53 isoform. Oncogene 30:15, pages 1764-1772.
Crossref
Crossref
Charlotte Hinault, Dan Kawamori, Chong Wee Liew, Bernhard Maier, Jiang Hu, Susanna R. Keller, Raghavendra G. Mirmira, Heidi Scrable & Rohit N. Kulkarni. (2011) Δ40 Isoform of p53 Controls β-Cell Proliferation and Glucose Homeostasis in Mice. Diabetes 60:4, pages 1210-1222.
Crossref
Crossref
Jin Woo Choi, Dae Gyu Kim, Al-Eum Lee, Hye Rim Kim, Jin Young Lee, Nam Hoon Kwon, Young Kee Shin, Soon-Kyung Hwang, Seung-Hee Chang, Myung-Haing Cho, Yoon-La Choi, Jhingook Kim, Seung Hyun Oh, Bora Kim, Soo-Youl Kim, Hyo-Sung Jeon, Jae Yong Park, Hyunseok Peter Kang, Bum Joon Park, Jung Min Han & Sunghoon Kim. (2011) Cancer-Associated Splicing Variant of Tumor Suppressor AIMP2/p38: Pathological Implication in Tumorigenesis. PLoS Genetics 7:3, pages e1001351.
Crossref
Crossref
Virginie Marcel, Phong L.T. Tran, Charlotte Sagne, Ghyslaine Martel-Planche, Laurence Vaslin, Marie-Paule Teulade-Fichou, Janet Hall, Jean-Louis Mergny, Pierre Hainaut & Eric Van Dyck. (2011) G-quadruplex structures in TP53 intron 3: role in alternative splicing and in production of p53 mRNA isoforms. Carcinogenesis 32:3, pages 271-278.
Crossref
Crossref
A. E. Vilgelm, A. I. Zaika & V. S. Prassolov. (2011) Coordinated interaction of multifunctional members of the p53 family determines many key processes in multicellular organisms. Molecular Biology 45:1, pages 156-171.
Crossref
Crossref
A. O. Zheltukhin & P. M. Chumakov. (2011) Constitutive and induced functions of the p53 gene. Biochemistry (Moscow) 75:13, pages 1692-1721.
Crossref
Crossref
Erica Ungewitter & Heidi Scrable. (2010) Δ40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs. Genes & Development 24:21, pages 2408-2419.
Crossref
Crossref
V Olivares-Illana & R Fåhraeus. (2010) p53 isoforms gain functions. Oncogene 29:37, pages 5113-5119.
Crossref
Crossref
V Marcel, V Vijayakumar, L Fernández-Cuesta, H Hafsi, C Sagne, A Hautefeuille, M Olivier & P Hainaut. (2010) p53 regulates the transcription of its Δ133p53 isoform through specific response elements contained within the TP53 P2 internal promoter. Oncogene 29:18, pages 2691-2700.
Crossref
Crossref
Mariana Pehar, Kenneth J. O’Riordan, Melissa Burns-Cusato, Matthew E. Andrzejewski, Carlos Gil del Alcazar, Corinna Burger, Heidi Scrable & Luigi Puglielli. (2010) Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death. Aging Cell 9:2, pages 174-190.
Crossref
Crossref
Karima Bourougaa, Nadia Naski, Cedric Boularan, Coraline Mlynarczyk, Marco M. Candeias, Stefano Marullo & Robin Fåhraeus. (2010) Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47. Molecular Cell 38:1, pages 78-88.
Crossref
Crossref
Ilaria Bellini, Letizia Pitto, Maria G. Marini, Loredana Porcu, Paolo Moi, Sonia Garritano, Laura Boldrini, Giuseppe Rainaldi, Gabriella Fontanini, Massimo Chiarugi, Roberto Barale, Federica Gemignani & Stefano Landi. (2010) ΔN133p53 expression levels in relation to haplotypes of the TP53 internal promoter region. Human Mutation 31:4, pages 456-465.
Crossref
Crossref
Alice Machado-Silva, Stéphane Perrier & Jean-Christophe Bourdon. (2010) p53 family members in cancer diagnosis and treatment. Seminars in Cancer Biology 20:1, pages 57-62.
Crossref
Crossref
Monica Hollstein & Pierre Hainaut. (2010)
Massively regulated genes: the example of
TP53
. The Journal of Pathology 220:2, pages 164-173.
Crossref
Crossref
Jun ChenJinrong Peng. (2009) p53 Isoform Δ113p53 in Zebrafish. Zebrafish 6:4, pages 389-395.
Crossref
Crossref
Konstantinos Lefkimmiatis, Mariano Francesco Caratozzolo, Paola Merlo, Anna Maria D'Erchia, Beatriz Navarro, Massimo Levrero, Elisabetta Sbisa'Apollonia Tullo. (2009) p73 and p63 Sustain Cellular Growth by Transcriptional Activation of Cell Cycle Progression Genes. Cancer Research 69:22, pages 8563-8571.
Crossref
Crossref
Pierre Hainaut & Klas G Wiman. (2009) 30 years and a long way into p53 research. The Lancet Oncology 10:9, pages 913-919.
Crossref
Crossref
R Grover, M M Candeias, R Fåhraeus & S Das. (2009) p53 and little brother p53/47: linking IRES activities with protein functions. Oncogene 28:30, pages 2766-2772.
Crossref
Crossref
Anirban Ghosh, Hemalatha Kuppusamy & Linda M. Pilarski. (2009) Aberrant Splice Variants of HAS1 (Hyaluronan Synthase 1) Multimerize with and Modulate Normally Spliced HAS1 Protein. Journal of Biological Chemistry 284:28, pages 18840-18850.
Crossref
Crossref
Janet Hall, Virginie Marcel, Celeste Bolin, Marie Fernet, Laurence Tartier, Laurence Vaslin & Pierre Hainaut. (2009) The associations of sequence variants in DNA-repair and cell-cycle genes with cancer risk: genotype–phenotype correlations. Biochemical Society Transactions 37:3, pages 527-533.
Crossref
Crossref
Sol Kim, Jungwoon Lee, Ja Young Kim, Bobae Lim, Eung-Kyun Shin, Yong-Mahn Han, Sung-Su Kim, Jin-Ho Song & Jungho Kim. (2009)
Mutation in the DNA-binding domain of the
EWS-Oct-4
oncogene results in dominant negative activity that interferes with EWS-Oct-4-mediated transactivation
. International Journal of Cancer 124:10, pages 2312-2322.
Crossref
Crossref
Aldona Kasprzak, Agnieszka Adamek, Wiesława Przybyszewska, Arkadiusz Czajka, Karolina Olejniczak, Jacek Juszczyk, Wiesława Biczysko & Maciej Zabel. (2009) p53 immunocytochemistry and TP53 gene mutations in patients with chronic hepatitis C virus (HCV) infection.. Folia Histochemica et Cytobiologica 47:1.
Crossref
Crossref
T. I. Pospelova, M. I. Voyevoda, Ye. N. Voropayeva, V. A. Belyavskaya, I. B. Kovynev & O. V. Berezina. (2008) Value of constitutional polymorphisms gene <i>р53</i> at patients with non-Hodgkin’s lymphomas. Bulletin of Siberian Medicine 7, pages 56-63.
Crossref
Crossref
Jennifer M. Rosenbluth & Jennifer A. Pietenpol. (2008) The jury is in: p73 is a tumor suppressor after all: Figure 1.. Genes & Development 22:19, pages 2591-2595.
Crossref
Crossref
Christopher A. Pettigrew, Nicola Wayte, Ania Wronski, Paul K. Lovelock, Amanda B. Spurdle & Melissa A. Brown. (2007) Colocalisation of predicted exonic splicing enhancers in BRCA2 with reported sequence variants. Breast Cancer Research and Treatment 110:2, pages 227-234.
Crossref
Crossref
Roman Hrstka, Darren J. Powell, Veronika Kvardova, Eva Roubalova, Karima Bourougaa, Marco M. Candeias, Petr Sova, Frantisek Zak, Robin Fåhraeus & Borivoj Vojtesek. (2008) The novel platinum(IV) complex LA-12 induces p53 and p53/47 responses that differ from the related drug, cisplatin. Anti-Cancer Drugs 19:4, pages 369-379.
Crossref
Crossref
Kelly A. Avery-Kiejda, Xu Dong Zhang, Luke J. Adams, Rodney J. Scott, Borivoj Vojtesek, David P. Lane & Peter Hersey. (2008) Small Molecular Weight Variants of p53 Are Expressed in Human Melanoma Cells and Are Induced by the DNA-Damaging Agent Cisplatin. Clinical Cancer Research 14:6, pages 1659-1668.
Crossref
Crossref
Roberta Malaguarnera, Veronica Vella, Giuseppe Pandini, Mariangela Sanfilippo, Vincenzo Pezzino, Riccardo Vigneri & Francesco Frasca. (2008) TAp73α Increases p53 Tumor Suppressor Activity in Thyroid Cancer Cells via the Inhibition of Mdm2-Mediated Degradation. Molecular Cancer Research 6:1, pages 64-77.
Crossref
Crossref
Roya Khosravi-Far & Eileen WhitePeter Hersey, Xu Dong Zhang & Nizar Mhaidat. 2008. Programmed Cell Death in Cancer Progression and Therapy. Programmed Cell Death in Cancer Progression and Therapy
105
126
.
Jean-Christophe Bourdon & David P. Lane. 2005. The Cancer Handbook. The Cancer Handbook.
Gerald Schmid, Matthias P. Kramer, Margarita Maurer, Stefanie Wandl & Józefa Węsierska-Gądek. (2007) Cellular and organismal ageing: Role of the p53 tumor suppressor protein in the induction of transient and terminal senescence. Journal of Cellular Biochemistry 101:6, pages 1355-1369.
Crossref
Crossref
Pierre Hainaut. 2009. Genes and Common Diseases. Genes and Common Diseases
233
244
.
J-C Bourdon. (2007) p53 and its isoforms in cancer. British Journal of Cancer 97:3, pages 277-282.
Crossref
Crossref
S Camus, S Menéndez, C F Cheok, L F Stevenson, S Laín & D P Lane. (2007) Ubiquitin-independent degradation of p53 mediated by high-risk human papillomavirus protein E6. Oncogene 26:28, pages 4059-4070.
Crossref
Crossref
Wan Mui Chan & Randy Y.C. Poon. (2007) The p53 Isoform Δp53 Lacks Intrinsic Transcriptional Activity and Reveals the Critical Role of Nuclear Import in Dominant-Negative Activity. Cancer Research 67:5, pages 1959-1969.
Crossref
Crossref
Linda Boldrup, Jean-Christophe Bourdon, Philip J. Coates, Björn Sjöström & Karin Nylander. (2007) Expression of p53 isoforms in squamous cell carcinoma of the head and neck. European Journal of Cancer 43:3, pages 617-623.
Crossref
Crossref
Bettina Couderc, Marie Penary, Mustapha Tohfe, Anne Pradines, Antoine Casteignau, Danièle Berg & Gilles Favre. (2006) Reversible inactivation of the transcriptional function of P53 protein by farnesylation. BMC Biotechnology 6:1.
Crossref
Crossref
Andrej Nikoshkov & Yasmin L. Hurd. (2006) p53 splice variants generated by atypical mRNA processing confer complexity of p53 transcripts in the human brain. Biochemical and Biophysical Research Communications 351:2, pages 383-386.
Crossref
Crossref
M M Candeias, D J Powell, E Roubalova, S Apcher, K Bourougaa, B Vojtesek, H Bruzzoni-Giovanelli & R Fåhraeus. (2006) Expression of p53 and p53/47 are controlled by alternative mechanisms of messenger RNA translation initiation. Oncogene 25:52, pages 6936-6947.
Crossref
Crossref
Ian R. Watson & Meredith S. Irwin. (2006) Ubiquitin and Ubiquitin-Like Modifications of the p53 Family. Neoplasia 8:8, pages 655-666.
Crossref
Crossref
Michihiro Takagi, Kazuhiko Ohashi, Toshifumi Morimura, Chihiro Sugimoto & Misao Onuma. (2006) The presence of the p53 transcripts with truncated open reading frames in Marek's disease tumor-derived cell lines. Leukemia Research 30:8, pages 987-992.
Crossref
Crossref
Nina Anensen, Anne Margrete Oyan, Jean-Christophe Bourdon, Karl Henning Kalland, Oystein Bruserud & Bjorn Tore Gjertsen. (2006) A Distinct p53 Protein Isoform Signature Reflects the Onset of Induction Chemotherapy for Acute Myeloid Leukemia. Clinical Cancer Research 12:13, pages 3985-3992.
Crossref
Crossref
F Murray-Zmijewski, D P Lane & J-C Bourdon. (2006) p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress. Cell Death & Differentiation 13:6, pages 962-972.
Crossref
Crossref
Francesco Frasca, Alessandra Rustighi, Roberta Malaguarnera, Sandro Altamura, Paolo Vigneri, Giannino Del Sal, Vincenzo Giancotti, Vincenzo Pezzino, Riccardo Vigneri & Guidalberto Manfioletti. (2006) HMGA1 Inhibits the Function of p53 Family Members in Thyroid Cancer Cells. Cancer Research 66:6, pages 2980-2989.
Crossref
Crossref
Cécile Delettre, Victor J. Yuste, Rana S. Moubarak, Marlène Bras, Jeanne-Claire Lesbordes-Brion, Stéphane Petres, Jacques Bellalou & Santos A. Susin. (2006) AIFsh, a Novel Apoptosis-inducing Factor (AIF) Pro-apoptotic Isoform with Potential Pathological Relevance in Human Cancer. Journal of Biological Chemistry 281:10, pages 6413-6427.
Crossref
Crossref
Michihiro TAKAGI, Tamami TAKEDA, Yuki ASADA, Chihiro SUGIMOTO, Misao ONUMA & Kazuhiko OHASHI. (2006) The Presence of a Short Form of p53 in Chicken Lymphoblastoid Cell Lines during Apoptosis. Journal of Veterinary Medical Science 68:6, pages 561-566.
Crossref
Crossref
Christopher Pettigrew, Nicola Wayte, Paul K Lovelock, Sean V Tavtigian, Georgia Chenevix-Trench, Amanda B Spurdle & Melissa A Brown. (2005) Evolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1gene with missense sequence changes and in-frame deletions, but not polymorphisms. Breast Cancer Research 7:6.
Crossref
Crossref
Alea A. Mills. (2005)
p53
: link to the past, bridge to the future
. Genes & Development 19:18, pages 2091-2099.
Crossref
Crossref
Jean-Christophe Bourdon, Kenneth Fernandes, Fiona Murray-Zmijewski, Geng Liu, Alexandra Diot, Dimitris P. Xirodimas, Mark K. Saville & David P. Lane. (2005) p53 isoforms can regulate p53 transcriptional activity. Genes & Development 19:18, pages 2122-2137.
Crossref
Crossref
Carolyn Cao, Eric T. Shinohara, Kenneth J. Niermann, Edwin F. Donnelly, Xinping Chen, Dennis E. Hallahan & Bo Lu. (2005) Murine double minute 2 as a therapeutic target for radiation sensitization of lung cancer. Molecular Cancer Therapeutics 4:8, pages 1137-1145.
Crossref
Crossref
Deborah Stewart, Anirban Ghosh & Greg Matlashewski. (2005) Involvement of Nuclear Export in Human Papillomavirus Type 18 E6-Mediated Ubiquitination and Degradation of p53. Journal of Virology 79:14, pages 8773-8783.
Crossref
Crossref
Christian Schwerk & Klaus Schulze-Osthoff. (2005) Regulation of Apoptosis by Alternative Pre-mRNA Splicing. Molecular Cell 19:1, pages 1-13.
Crossref
Crossref
Gabor Rohaly, Jan Chemnitz, Silke Dehde, Alejandro Mena Nunez, Jochen Heukeshoven, Wolfgang Deppert & Irena Dornreiter. (2005) A Novel Human p53 Isoform Is an Essential Element of the ATR-Intra-S Phase Checkpoint. Cell 122:1, pages 21-32.
Crossref
Crossref
Kurt W. Kohn & Yves Pommier. (2005) Molecular interaction map of the p53 and Mdm2 logic elements, which control the Off–On switch of p53 in response to DNA damage. Biochemical and Biophysical Research Communications 331:3, pages 816-827.
Crossref
Crossref
Heidi Scrable, Tsutomu Sasaki & Bernhard Maier. (2005) ΔNp53 or p44: priming the p53 pump. The International Journal of Biochemistry & Cell Biology 37:5, pages 913-919.
Crossref
Crossref
Philip J Coates, Sally A Lorimore & Eric G Wright. (2005) Cell and tissue responses to genotoxic stress. The Journal of Pathology 205:2, pages 221-235.
Crossref
Crossref