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Cell Growth and Development

Casein Kinase Iε Modulates the Signaling Specificities of Dishevelled

Feng CongProgram in Cell Biology, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York10021Correspondence[email protected]
,
Liang SchweizerProgram in Cell Biology, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York10021
&
Harold VarmusProgram in Cell Biology, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York10021
Pages 2000-2011 | Received 01 Jul 2003, Accepted 25 Nov 2003, Published online: 27 Mar 2023

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Yanpeng Xiong, Liang Zhou, Zijie Su, Jiaxing Song, Qi Sun, Shan-Shan Liu, Yuqing Xia, Zhongyuan Wang & Desheng Lu. (2019) Longdaysin inhibits Wnt/β-catenin signaling and exhibits antitumor activity against breast cancer. OncoTargets and Therapy 12, pages 993-1005.
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Crossref
Stephanie Grainger & Karl Willert. (2018) Mechanisms of Wnt signaling and control. WIREs Systems Biology and Medicine 10:5.
Crossref
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Crossref
Monica Sharma, Isabel Castro-Piedras, Glenn E. SimmonsJrJr & Kevin Pruitt. (2018) Dishevelled: A masterful conductor of complex Wnt signals. Cellular Signalling 47, pages 52-64.
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Crossref
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Crossref
NaveenKumar Perumal, MadanKumar Perumal, Anbarasu Kannan, Kumar Subramani, Devaraj Halagowder & NiranjaliDevaraj Sivasithamparam. (2017) Morin impedes Yap nuclear translocation and fosters apoptosis through suppression of Wnt/β-catenin and NF-κB signaling in Mst1 overexpressed HepG2 cells. Experimental Cell Research 355:2, pages 124-141.
Crossref
Verena Rauschenberger, Dominic B. Bernkopf, Sabrina Krenn, Kowcee Jalal, Jens Heller, Jürgen Behrens, Marc Gentzel & Alexandra Schambony. (2017) The phosphatase Pgam5 antagonizes Wnt/β-Catenin signaling in embryonic anterior-posterior axis patterning. Development.
Crossref
Fabian H. Jenny & Konrad Basler. (2016) Drosophila DDX3/Belle Exerts Its Function Outside of the Wnt/Wingless Signaling Pathway. PLOS ONE 11:12, pages e0166862.
Crossref
Emma E. Laing, Jonathan D. Johnston, Carla S. Möller-Levet, Giselda Bucca, Colin P. Smith, Derk-Jan Dijk & Simon N. Archer. (2015) Exploiting human and mouse transcriptomic data: Identification of circadian genes and pathways influencing health. BioEssays 37:5, pages 544-556.
Crossref
Cristina-Maria Cruciat. (2014) Casein kinase 1 and Wnt/β-catenin signaling. Current Opinion in Cell Biology 31, pages 46-55.
Crossref
Nobuyuki Shimizu, Shizuka Ishitani, Atsushi Sato, Hiroshi Shibuya & Tohru Ishitani. (2014) Hipk2 and PP1c Cooperate to Maintain Dvl Protein Levels Required for Wnt Signal Transduction. Cell Reports 8:5, pages 1391-1404.
Crossref
Ondřej Bernatík, Kateřina Šedová, Carolin Schille, Ranjani Sri Ganji, Igor Červenka, Lukáš Trantírek, Alexandra Schambony, Zbyněk Zdráhal & Vítězslav Bryja. (2014) Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1ϵ and Frizzled5. Journal of Biological Chemistry 289:34, pages 23520-23533.
Crossref
M Asad, M K Wong, T Z Tan, M Choolani, J Low, S Mori, D Virshup, J P Thiery & R Y-J Huang. (2014) FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway. Cell Death & Disease 5:7, pages e1346-e1346.
Crossref
Alexandra Schambony, Guido J.R. Zaman & Folkert Verkaar. 2014. Wnt Signaling in Development and Disease. Wnt Signaling in Development and Disease 101 112 .
Tony W. Chen, Heather A. Wallace, Yashi Ahmed & Ethan Lee. 2014. Wnt Signaling in Development and Disease. Wnt Signaling in Development and Disease 33 49 .
Vítězslav Bryja & Ondřej Bernatík. 2014. Wnt Signaling in Development and Disease. Wnt Signaling in Development and Disease 207 216 .
J P Dijksterhuis, J Petersen & G Schulte. (2014) WNT/Frizzled signalling: receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3. British Journal of Pharmacology 171:5, pages 1195-1209.
Crossref
Fei Xu, Yan-lin Wang, Jiao-jiao Chang, Si-chen Du, Lei Diao, Nan Jiang, Hui-jun Wang, Duan Ma & Jin Zhang. (2014) Mammalian sterile 20-like kinase 1/2 inhibits the Wnt/β-catenin signalling pathway by directly binding casein kinase 1ε. Biochemical Journal 458:1, pages 159-169.
Crossref
Ekatherina Serysheva, Hebist Berhane, Luca Grumolato, Kubilay Demir, Sophie Balmer, Maxime Bodak, Michael Boutros, Stuart Aaronson, Marek Mlodzik & Andreas Jenny. (2013) Wnk kinases are positive regulators of canonical Wnt/β‐catenin signalling. EMBO reports 14:8, pages 718-725.
Crossref
Eun-Young Shin, Edmond Changkyun Park, Yeonhee Hong & Gun-Hwa Kim. (2013) Protein Kinases Involved in the Regulation of Wnt/β-catenin Signaling. Journal of Life Science 23:7, pages 947-954.
Crossref
Jaskirat Singh & Marek Mlodzik. (2012) Planar cell polarity signaling: coordination of cellular orientation across tissues. Wiley Interdisciplinary Reviews: Developmental Biology 1:4, pages 479-499.
Crossref
Noriko Yokoyama, Nelli G Markova, Hsien-yu Wang & Craig C Malbon. (2012) Assembly of Dishevelled 3-based supermolecular complexes via phosphorylation and Axin. Journal of Molecular Signaling 7, pages 8.
Crossref
Wang A. Yanfeng, Hebist Berhane, Marion Mola, Jaskirat Singh, Andreas Jenny & Marek Mlodzik. (2011) Functional dissection of phosphorylation of Disheveled in Drosophila. Developmental Biology 360:1, pages 132-142.
Crossref
M. B. C. Kilander, C. Halleskog & G. Schulte. (2011) Recombinant WNTs differentially activate β-catenin-dependent and -independent signalling in mouse microglia-like cells. Acta Physiologica 203:3, pages 363-372.
Crossref
Yoshimi Endo Greer & Jeffrey S. Rubin. (2011) Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a–dependent neurite outgrowth. Journal of Cell Biology 192:6, pages 993-1004.
Crossref
Yi-Tong Liu, Qiong-Jie Dan, Jiawei Wang, Yingang Feng, Lei Chen, Juan Liang, Qinxi Li, Sheng-Cai Lin, Zhi-Xin Wang & Jia-Wei Wu. (2011) Molecular Basis of Wnt Activation via the DIX Domain Protein Ccd1. Journal of Biological Chemistry 286:10, pages 8597-8608.
Crossref
Ondrej Bernatik, Ranjani Sri Ganji, Jacomijn P. Dijksterhuis, Peter Konik, Igor Cervenka, Tilman Polonio, Pavel Krejci, Gunnar Schulte & Vitezslav Bryja. (2011) Sequential Activation and Inactivation of Dishevelled in the Wnt/β-Catenin Pathway by Casein Kinases. Journal of Biological Chemistry 286:12, pages 10396-10410.
Crossref
Gunnar Schulte. (2010) International Union of Basic and Clinical Pharmacology. LXXX. The Class Frizzled Receptors. Pharmacological Reviews 62:4, pages 632-667.
Crossref
Jaskirat Singh, Wang A. Yanfeng, Luca Grumolato, Stuart A. Aaronson & Marek Mlodzik. (2010) Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation. Genes & Development 24:19, pages 2157-2168.
Crossref
Gunnar Schulte. 2010. GPCR Molecular Pharmacology and Drug Targeting. GPCR Molecular Pharmacology and Drug Targeting 113 137 .
Florian Witte, Ondrej Bernatik, Katharina Kirchner, Jan Masek, Annika Mahl, Pavel Krejci, Stefan Mundlos, Alexandra Schambony, Vitezslav Bryja & Sigmar Stricker. (2010) Negative regulation of Wnt signaling mediated by CK1‐phosphorylated Dishevelled via Ror2 . The FASEB Journal 24:7, pages 2417-2426.
Crossref
Silvie Foldynová-Trantírková, Petra Sekyrová, Kateřina Tmejová, Eva Brumovská, Ondřej Bernatík, Wulf Blankenfeldt, Pavel Krejčí, Alois Kozubík, Tomáš Doležal, Lukáš Trantírek & Vítězslav Bryja. (2010) Breast cancer-specific mutations in CK1ε inhibit Wnt/β-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration. Breast Cancer Research 12:3.
Crossref
Kimberly R. Holloway, Tara N. Calhoun, Madhurima Saxena, Cheynita F. Metoyer, Ethan F. Kandler, Chantal A. Rivera & Kevin Pruitt. (2010) SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling. Proceedings of the National Academy of Sciences 107:20, pages 9216-9221.
Crossref
Tianhui Hu, Cunxi Li, Zheng Cao, Terence J. Van Raay, Jason G. Smith, Karl Willert, Lila Solnica-Krezel & Robert J. Coffey. (2010) Myristoylated Naked2 Antagonizes Wnt-β-Catenin Activity by Degrading Dishevelled-1 at the Plasma Membrane. Journal of Biological Chemistry 285:18, pages 13561-13568.
Crossref
Gunnar Schulte, Alexandra Schambony & Vítězslav Bryja. (2010) β-arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?. British Journal of Pharmacology 159:5, pages 1051-1058.
Crossref
Dianqing Wu & Weijun Pan. (2010) GSK3: a multifaceted kinase in Wnt signaling. Trends in Biochemical Sciences 35:3, pages 161-168.
Crossref
R van Amerongen, M C Nawijn, J -P Lambooij, N Proost, J Jonkers & A Berns. (2009) Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways. Oncogene 29:1, pages 93-104.
Crossref
Helen McNeill. (2009) Planar Cell Polarity and the Kidney. Journal of the American Society of Nephrology 20:10, pages 2104-2111.
Crossref
Jeffrey D. Axelrod. (2009) Progress and challenges in understanding planar cell polarity signaling. Seminars in Cell & Developmental Biology 20:8, pages 964-971.
Crossref
David D. O'Keefe, Eduardo Gonzalez-Niño, Micheal Burnett, Layne Dylla, Stacey M. Lambeth, Elizabeth Licon, Cassandra Amesoli, Bruce A. Edgar & Jennifer Curtiss. (2009) Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila. Developmental Biology 333:1, pages 143-160.
Crossref
N Bouteille, K Driouch, P El Hage, S Sin, E Formstecher, J Camonis, R Lidereau & F Lallemand. (2009) Inhibition of the Wnt/β-catenin pathway by the WWOX tumor suppressor protein. Oncogene 28:28, pages 2569-2580.
Crossref
Evelyn Teran, Aron D. Branscomb & Joni M. Seeling. (2009) Dpr Acts as a Molecular Switch, Inhibiting Wnt Signaling when Unphosphorylated, but Promoting Wnt Signaling when Phosphorylated by Casein Kinase Iδ/ε. PLoS ONE 4:5, pages e5522.
Crossref
Caroline Lund Dahlberg, Elizabeth Z. Nguyen, David Goodlett & David Kimelman. (2009) Interactions between Casein Kinase Iε (CKIε) and Two Substrates from Disparate Signaling Pathways Reveal Mechanisms for Substrate-Kinase Specificity. PLoS ONE 4:3, pages e4766.
Crossref
RL Bacallao & H McNeill. (2009) Cystic kidney diseases and planar cell polarity signaling. Clinical Genetics 75:2, pages 107-117.
Crossref
Cristina Modak. (2009) Potential of casein kinase I in digestive cancer screening. World Journal of Gastrointestinal Oncology 1:1, pages 26.
Crossref
Joseph H. Sellin, Yu Wang, Pomila Singh & Shahid Umar. (2009) β-Catenin stabilization imparts crypt progenitor phenotype to hyperproliferating colonic epithelia. Experimental Cell Research 315:1, pages 97-109.
Crossref
Esther M. Verheyen & Cara J. Gottardi. (2009) Regulation of Wnt/β-catenin signaling by protein kinases. Developmental Dynamics, pages NA-NA.
Crossref
Yasuhiro Minami, Isao Oishi, Mitsuharu Endo & Michiru Nishita. (2009) Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases. Developmental Dynamics, pages NA-NA.
Crossref
Matias SimonsMarek Mlodzik. (2008) Planar Cell Polarity Signaling: From Fly Development to Human Disease. Annual Review of Genetics 42:1, pages 517-540.
Crossref
Yosuke Funato, Tatsuo Michiue, Takeshi Terabayashi, Akira Yukita, Hiroki Danno, Makoto Asashima & Hiroaki Miki. (2008) Nucleoredoxin regulates the Wnt/planar cell polarity pathway in Xenopus . Genes to Cells 13:9, pages 965-975.
Crossref
Ildiko M. L. Somorjai & Alfonso Martinez-Arias. (2008) Wingless Signalling Alters the Levels, Subcellular Distribution and Dynamics of Armadillo and E-Cadherin in Third Instar Larval Wing Imaginal Discs. PLoS ONE 3:8, pages e2893.
Crossref
Hans A Kestler & Michael Kühl. (2008) From individual Wnt pathways towards a Wnt signalling network. Philosophical Transactions of the Royal Society B: Biological Sciences 363:1495, pages 1333-1347.
Crossref
L Garzia, A D'Angelo, A Amoresano, S K Knauer, C Cirulli, C Campanella, R H Stauber, C Steegborn, A Iolascon & M Zollo. (2007) Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility. Oncogene 27:13, pages 1853-1864.
Crossref
Jun Wu, Andreas Jenny, Ivana Mirkovic & Marek Mlodzik. (2008) Frizzled–Dishevelled signaling specificity outcome can be modulated by Diego in Drosophila. Mechanisms of Development 125:1-2, pages 30-42.
Crossref
Richard G. James, William H. Conrad & Randall T. Moon. 2008. Wnt Signaling. Wnt Signaling 131 144 .
Suk Mei Wang, London Lucien P.J. Ooi & Kam M. Hui. (2007) Identification and Validation of a Novel Gene Signature Associated with the Recurrence of Human Hepatocellular Carcinoma. Clinical Cancer Research 13:21, pages 6275-6283.
Crossref
Thomas Schlange, Yutaka Matsuda, Susanne Lienhard, Alexandre Huber & Nancy E Hynes. (2007) Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation. Breast Cancer Research 9:5.
Crossref
Thomas ForceKathleen WoulfeWalter J. KochRisto Kerkelä. (2007) Molecular Scaffolds Regulate Bidirectional Crosstalk Between Wnt and Classical Seven-Transmembrane Domain Receptor Signaling Pathways. Science's STKE 2007:397.
Crossref
Thomas Schwarz-Romond, Ciara Metcalfe & Mariann Bienz. (2007) Dynamic recruitment of axin by Dishevelled protein assemblies. Journal of Cell Science 120:14, pages 2402-2412.
Crossref
Jennifer D. Leonard & Charles A. Ettensohn. (2007) Analysis of dishevelled localization and function in the early sea urchin embryo. Developmental Biology 306:1, pages 50-65.
Crossref
Raymond Habas & Xi He. (2007) Cell Signaling: Moving to a Wnt-Rap. Current Biology 17:12, pages R474-R477.
Crossref
Ginny G. Farías, Ana S. Vallés, Marcela Colombres, Juan A. Godoy, Enrique M. Toledo, Ronald J. Lukas, Francisco J. Barrantes & Nibaldo C. Inestrosa. (2007) Wnt-7a Induces Presynaptic Colocalization of α7-Nicotinic Acetylcholine Receptors and Adenomatous Polyposis Coli in Hippocampal Neurons. The Journal of Neuroscience 27:20, pages 5313-5325.
Crossref
Marc Flajolet, Gen He, Myriam Heiman, Angie Lin, Angus C. Nairn & Paul Greengard. (2007) Regulation of Alzheimer's disease amyloid-β formation by casein kinase I. Proceedings of the National Academy of Sciences 104:10, pages 4159-4164.
Crossref
Ju Guan, Hui Li, Ana Rogulja, Jeff D. Axelrod & Ken M. Cadigan. (2007) The Drosophila casein kinase Iε/δ Discs overgrown promotes cell survival via activation of DIAP1 expression. Developmental Biology 303:1, pages 16-28.
Crossref
I-Chun Tsai, Margaret Woolf, Deborah W. Neklason, William W. Branford, H. Joseph Yost, Randall W. Burt & David M. Virshup. (2006) Disease-associated casein kinase I δ mutation may promote adenomatous polyps formation via a Wnt/β-catenin independent mechanism. International Journal of Cancer 120:5, pages 1005-1012.
Crossref
Vítězslav Bryja, Gunnar Schulte, Nina Rawal, Alexandra Grahn & Ernest Arenas. (2007) Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. Journal of Cell Science 120:4, pages 586-595.
Crossref
D Kimelman & W Xu. (2006) β-Catenin destruction complex: insights and questions from a structural perspective. Oncogene 25:57, pages 7482-7491.
Crossref
Lei Zhang, Jianhang Jia, Bing Wang, Kazuhito Amanai, Keith A. WhartonJr.Jr. & Jin Jiang. (2006) Regulation of wingless signaling by the CKI family in Drosophila limb development. Developmental Biology 299:1, pages 221-237.
Crossref
Laura K. Klimowski, Benjamin A. Garcia, Jeffrey Shabanowitz, Donald F. Hunt & David M. Virshup. (2006) Site-specific casein kinase 1ε-dependent phosphorylation of Dishevelled modulates β-catenin signaling. FEBS Journal 273:20, pages 4594-4602.
Crossref
Thomas J. Klein, Andreas Jenny, Alexandre Djiane & Marek Mlodzik. (2006) CKIɛ/discs overgrown Promotes Both Wnt-Fz/β-Catenin and Fz/PCP Signaling in Drosophila. Current Biology 16:13, pages 1337-1343.
Crossref
Helen Strutt, Mary Ann Price & David Strutt. (2006) Planar Polarity Is Positively Regulated by Casein Kinase Iɛ in Drosophila. Current Biology 16:13, pages 1329-1336.
Crossref
Nan Zhong, Robert P. Gersch & Michael Hadjiargyrou. (2006) Wnt signaling activation during bone regeneration and the role of Dishevelled in chondrocyte proliferation and differentiation. Bone 39:1, pages 5-16.
Crossref
Wojciech Swiatek, Heeseog Kang, Benjamin A. Garcia, Jeffery Shabanowitz, Gary S. Coombs, Donald F. Hunt & David M. Virshup. (2006) Negative Regulation of LRP6 Function by Casein Kinase I ϵ Phosphorylation. Journal of Biological Chemistry 281:18, pages 12233-12241.
Crossref
Birgit Gustafson & Ulf Smith. (2006) Cytokines Promote Wnt Signaling and Inflammation and Impair the Normal Differentiation and Lipid Accumulation in 3T3-L1 Preadipocytes. Journal of Biological Chemistry 281:14, pages 9507-9516.
Crossref
Stephane Angers, Chris J. Thorpe, Travis L. Biechele, Seth J. Goldenberg, Ning Zheng, Michael J. MacCoss & Randall T. Moon. (2006) The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation. Nature Cell Biology 8:4, pages 348-357.
Crossref
Mary Ann Price. (2006) CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling. Genes & Development 20:4, pages 399-410.
Crossref
Ken M. Cadigan & Yan I. Liu. (2006) Wnt signaling: complexity at the surface. Journal of Cell Science 119:3, pages 395-402.
Crossref
Trevor Dale. (2006) Kinase cogs go forward and reverse in the Wnt signaling machine. Nature Structural & Molecular Biology 13:1, pages 9-11.
Crossref
John B. Wallingford & Raymond Habas. (2005) The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development 132:20, pages 4421-4436.
Crossref
Sakura Saburi & Helen McNeill. (2005) Organising cells into tissues: new roles for cell adhesion molecules in planar cell polarity. Current Opinion in Cell Biology 17:5, pages 482-488.
Crossref
M. Sen. (2005) Wnt signalling in rheumatoid arthritis. Rheumatology 44:6, pages 708-713.
Crossref
Tae Joo Park, Ryan S. Gray, Akira Sato, Raymond Habas & John B. Wallingford. (2005) Subcellular Localization and Signaling Properties of Dishevelled in Developing Vertebrate Embryos. Current Biology 15:11, pages 1039-1044.
Crossref
Uwe Knippschild, Andreas Gocht, Sonja Wolff, Nadine Huber, Jürgen Löhler & Martin Stöter. (2005) The casein kinase 1 family: participation in multiple cellular processes in eukaryotes. Cellular Signalling 17:6, pages 675-689.
Crossref
Sun-Cheol Choi & Jin-Kwan Han. (2005) Rap2 is required for Wnt/β-catenin signaling pathway in Xenopus early development. The EMBO Journal 24:5, pages 985-996.
Crossref
Gunnar Schulte, Vítězslav Bryja, Nina Rawal, Goncalo Castelo-Branco, Kyle M. Sousa & Ernest Arenas. (2005) Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. Journal of Neurochemistry 92:6, pages 1550-1553.
Crossref
Daniel Kalderon. (2005) Hedgehog Signaling: An Arrestin Connection?. Current Biology 15:5, pages R175-R178.
Crossref
Timothy Walston, Christina Tuskey, Lois Edgar, Nancy Hawkins, Gregory Ellis, Bruce Bowerman, William Wood & Jeff Hardin. (2004) Multiple Wnt Signaling Pathways Converge to Orient the Mitotic Spindle in Early C. elegans Embryos. Developmental Cell 7:6, pages 831-841.
Crossref
Feng Cong, Liang Schweizer & Harold Varmus. (2004) Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development 131:20, pages 5103-5115.
Crossref
Wei Jun PAN, Shu Zhao PANG, Tao HUANG, Hui Yun GUO, Dianqing WU & Lin LI. (2004) Characterization of Function of Three Domains in Dishevelled-1: DEP Domain is Responsible for Membrane Translocation of Dishevelled-1. Cell Research 14:4, pages 324-330.
Crossref

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