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Erik O. Pettersen, Peter Ebbesen, Roben G. Gieling, Kaye J. Williams, Ludwig Dubois, Philippe Lambin, Carol Ward, James Meehan, Ian H. Kunkler, Simon P. Langdon, Anne H. Ree, Kjersti Flatmark, Heidi Lyng, Maria J. Calzada, Luis del Peso, Manuel O. Landazuri, Agnes Görlach, Hubert Flamm, Jochen Kieninger, Gerald Urban, Andreas Weltin, Dean C. Singleton, Syed Haider, Francesca M. Buffa, Adrian L. Harris, Andrea Scozzafava, Claudiu T. Supuran, Isabella Moser, Gerhard Jobst, Morten Busk, Kasper Toustrup, Jens Overgaard, Jan Alsner, Jacques Pouyssegur, Johanna Chiche, Nathalie Mazure, Ibtissam Marchiq, Scott Parks, Afshan Ahmed, Margaret Ashcroft, Silvia Pastorekova, Yihai Cao, Kasper M. Rouschop, Brad G. Wouters, Marianne Koritzinsky, Hilda Mujcic & Dan Cojocari. (2015) Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium. Journal of Enzyme Inhibition and Medicinal Chemistry 30:5, pages 689-721.
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Daniela Mennerich, Elitsa Y Dimova & Thomas Kietzmann. (2014) Direct phosphorylation events involved in HIF-1 regulation: the role of GSK-3. Hypoxia 2, pages 35-45.
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Carolyn Culver, Andrew Melvin, Sharon Mudie & Sonia Rocha. (2011) HIF-1α depletion results in SP1-mediated cell cycle disruption and alters the cellular response to chemotherapeutic drugs. Cell Cycle 10:8, pages 1249-1260.
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Daniela Flügel, Agnes Görlach, Carine Michiels & Thomas Kietzmann. (2007) Glycogen Synthase Kinase 3 Phosphorylates Hypoxia-Inducible Factor 1α and Mediates Its Destabilization in a VHL-Independent Manner. Molecular and Cellular Biology 27:9, pages 3253-3265.
Read now
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Rachida S Bel Aiba, Elitsa Y Dimova, Agnes Görlach & Thomas Kietzmann. (2006) The role of hypoxia inducible factor-1 in cell metabolism – a possible target in cancer therapy. Expert Opinion on Therapeutic Targets 10:4, pages 583-599.
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Susanne J Rogers, Carol Box, Kevin J Harrington, Chris Nutting, Peter Rhys-Evans & Suzanne A Eccles. (2005) The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck. Expert Opinion on Therapeutic Targets 9:4, pages 769-790.
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Anna Lasorella, Gerson Rothschild, Yoshifumi Yokota, Robert G. Russell & Antonio Iavarone. (2005) Id2 Mediates Tumor Initiation, Proliferation, and Angiogenesis in Rb Mutant Mice. Molecular and Cellular Biology 25:9, pages 3563-3574.
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Articles from other publishers (66)
Oana Gabriela Trifanescu, Laurentia Nicoleta Gales, Bogdan Cosmin Tanase, Serban Andrei Marinescu, Raluca Alexandra Trifanescu, Iuliana Maria Gruia, Mihai Andrei Paun, Laura Rebegea, Radu Mitrica, Luiza Serbanescu & Rodica Maricela Anghel. (2023) Prognostic Role of Vascular Endothelial Growth Factor and Correlation with Oxidative Stress Markers in Locally Advanced and Metastatic Ovarian Cancer Patients. Diagnostics 13:1, pages 166.
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Yinhong Zhu, Xiaoran Zhang, Shujuan Xie, Weijia Bao, Jingrou Chen, Qili Wu, Xiaorong Lai, Longshan Liu, Shiqiu Xiong & Yanwen Peng. (2022) Oxidative phosphorylation regulates interleukin‐10 production in regulatory B cells via the extracellular signal‐related kinase pathway. Immunology 167:4, pages 576-589.
Crossref
Crossref
Corbin C. Jensen & Noel A. Warfel. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology
438
468
.
Chaofeng Shi, Zhengchao Li, Yuqiang Wu, Xia Li, Yaxiao Li, Jinxia Wei, JianYu Li, Yongliang Zhang & Lingzhi Li. (2020) Euscaphic acid and Tormentic acid protect vascular endothelial cells against hypoxia-induced apoptosis via PI3K/AKT or ERK 1/2 signaling pathway. Life Sciences 252, pages 117666.
Crossref
Crossref
Brian Lam & Emilie Roudier. (2019) Considering the Role of Murine Double Minute 2 in the Cardiovascular System?. Frontiers in Cell and Developmental Biology 7.
Crossref
Crossref
Julian Aiken, Erin R Mandel, Michael C Riddell & Olivier Birot. (2018) Hyperglycaemia correlates with skeletal muscle capillary regression and is associated with alterations in the murine double minute-2/forkhead box O1/thrombospondin-1 pathway in type 1 diabetic BioBreeding rats. Diabetes and Vascular Disease Research 16:1, pages 28-37.
Crossref
Crossref
Youbang Xie, Xuefeng Shi, Kuo Sheng, Guoxiong Han, Wenqian Li, Qiangqiang Zhao, Baili Jiang, Jianming Feng, Jianping Li & Yuhai Gu. (2018) PI3K/Akt signaling transduction pathway, erythropoiesis and glycolysis in hypoxia (Review). Molecular Medicine Reports.
Crossref
Crossref
Paula M. Hauck, Eric R. Wolf, David J. OlivosIIIIII, Christopher N. Batuello, Kyle C. McElyea, Ciarán P. McAtarsney, R. Michael Cournoyer, George E. Sandusky & Lindsey D. Mayo. (2017) Early-Stage Metastasis Requires Mdm2 and Not p53 Gain of Function. Molecular Cancer Research 15:11, pages 1598-1607.
Crossref
Crossref
Julia Günter, Amalia Ruiz-Serrano, Christina Pickel, Roland H. Wenger & Carsten C. Scholz. (2017) The functional interplay between the HIF pathway and the ubiquitin system – more than a one-way road. Experimental Cell Research 356:2, pages 152-159.
Crossref
Crossref
Julian Aiken, Emilie Roudier, Joseph Ciccone, Genevieve Drouin, Anna Stromberg, Jovana Vojnovic, I. Mark Olfert, Tara Haas, Thomas Gustafsson, Guillaume Grenier & Olivier Birot. (2015)
Phosphorylation of murine double minute‐2 on Ser
166
is downstream of VEGF‐A in exercised skeletal muscle and regulates primary endothelial cell migration and
FoxO
gene expression
. The FASEB Journal 30:3, pages 1120-1134.
Crossref
Crossref
Thomas Kietzmann, Daniela Mennerich & Elitsa Y. Dimova. (2016) Hypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and Transactivity. Frontiers in Cell and Developmental Biology 4.
Crossref
Crossref
Ivano Amelio & Gerry Melino. (2015) The p53 family and the hypoxia-inducible factors (HIFs): determinants of cancer progression. Trends in Biochemical Sciences 40:8, pages 425-434.
Crossref
Crossref
Guo-Hua Dai, Pei-Ze Ma, Xian-Bo Song, Ning Liu, Tong Zhang & Bo Wu. (2014) MicroRNA-223-3p Inhibits the Angiogenesis of Ischemic Cardiac Microvascular Endothelial Cells via Affecting RPS6KB1/hif-1a Signal Pathway. PLoS ONE 9:10, pages e108468.
Crossref
Crossref
Shweta Joshi, Alok R. Singh & Donald L. Durden. (2014) MDM2 Regulates Hypoxic Hypoxia-inducible Factor 1α Stability in an E3 Ligase, Proteasome, and PTEN-Phosphatidylinositol 3-Kinase-AKT-dependent Manner. Journal of Biological Chemistry 289:33, pages 22785-22797.
Crossref
Crossref
Zsolt Fábián, Sivaramakrishnan Ramadurai, Georgina Shaw, Heinz-Peter Nasheuer, Walter Kolch, Cormac Taylor & Frank Barry. (2014) Basic fibroblast growth factor modifies the hypoxic response of human bone marrow stromal cells by ERK-mediated enhancement of HIF-1α activity. Stem Cell Research 12:3, pages 646-658.
Crossref
Crossref
E. Douglas Robertson, Kostyantyn Semenchenko & Bohdan Wasylyk. 2014. Mutant p53 and MDM2 in Cancer. Mutant p53 and MDM2 in Cancer
199
214
.
Jason A. Lehman, Paula M. Hauck, Jaimie M. Gendron, Christopher N. Batuello, Jacob A. Eitel, Allan Albig, Madhavi P. Kadakia & Lindsey D. Mayo. (2013) Serdemetan Antagonizes the Mdm2-HIF1α Axis Leading to Decreased Levels of Glycolytic Enzymes. PLoS ONE 8:9, pages e74741.
Crossref
Crossref
Emilie Roudier, Paul Forn, Mary Ellen Perry & Olivier Birot. (2012) Murine double minute‐2 expression is required for capillary maintenance and exercise‐induced angiogenesis in skeletal muscle. The FASEB Journal 26:11, pages 4530-4539.
Crossref
Crossref
MM Sun, MZ Zhang, Y Chen, SL Li, W Zhang, GW Ya & KS Chen. (2012) Mechanistic Target of Rapamycin Small Interfering RNA and Rapamycin Synergistically Inhibit Tumour Growth in a Mouse Xenograft Model of Human Oesophageal Carcinoma. Journal of International Medical Research 40:5, pages 1636-1643.
Crossref
Crossref
J-H Park, J-Y Lee, D-H Shin, K-S Jang, H-J Kim & Gu Kong. (2011) Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway. Oncogene 30:45, pages 4578-4589.
Crossref
Crossref
Danielle M. Patterson, Dongbing Gao, Denae N. Trahan, Brett A. Johnson, Andrew Ludwig, Eveline Barbieri, Zaowen Chen, Jose Diaz-Miron, Lyubomir Vassilev, Jason M. Shohet & Eugene S. Kim. (2011) Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma. Angiogenesis 14:3, pages 255-266.
Crossref
Crossref
C. Chargari, C. Leteur, C. Ferté, M. Deberne, B. Lahon, C. Rivera, J. Bourhis & É. Deutsch. (2011) Ciblage pharmacologique de Mdm2 : bases biologiques et perspectives de radiosensibilisation. Cancer/Radiothérapie 15:4, pages 316-322.
Crossref
Crossref
Ian P. Newton, Niall S. Kenneth, Paul L. Appleton, Inke Näthke & Sonia Rocha. (2010) Adenomatous Polyposis Coli and Hypoxia-inducible Factor-1α Have an Antagonistic Connection. Molecular Biology of the Cell 21:21, pages 3630-3638.
Crossref
Crossref
Hamid Reza Rezvani, Frédéric Mazurier, Fanny Morice-Picard, Thomas Jouary, Muriel Cario-André, Cécile Ged, Hubert de Verneuil & Alain Taïeb. (2010) Xeroderma pigmentosum: clues to understanding cancer initiation. Dermatologica Sinica 28:3, pages 93-101.
Crossref
Crossref
Majed S. Al Okail. (2010) Cobalt chloride, a chemical inducer of hypoxia-inducible factor-1α in U251 human glioblastoma cell line. Journal of Saudi Chemical Society 14:2, pages 197-201.
Crossref
Crossref
Paola Dongiovanni, Anna Ludovica Fracanzani, Gaetano Cairo, Chiara Paola Megazzini, Stefano Gatti, Raffaela Rametta, Silvia Fargion & Luca Valenti. (2010) Iron-Dependent Regulation of MDM2 Influences p53 Activity and Hepatic Carcinogenesis. The American Journal of Pathology 176:2, pages 1006-1017.
Crossref
Crossref
Shinako Araki, Jacob A. Eitel, Christopher N. Batuello, Khadijeh Bijangi-Vishehsaraei, Xian-Jin Xie, David Danielpour, Karen E. Pollok, David A. Boothman & Lindsey D. Mayo. (2010) TGF-β1–induced expression of human Mdm2 correlates with late-stage metastatic breast cancer. Journal of Clinical Investigation 120:1, pages 290-302.
Crossref
Crossref
Yan Liu, Csaba László, Yi Liu, Wei Liu, Xiaozhuo Chen, Susan C. Evans & Shiyong Wu. (2010) Regulation of G1 Arrest and Apoptosis in Hypoxia by PERK and GCN2-Mediated eIF2α Phosphorylation. Neoplasia 12:1, pages 61-IN6.
Crossref
Crossref
Hamid Reza Rezvani, Walid Mahfouf, Nsrein Ali, Cecile Chemin, Cecile Ged, Arianna L. Kim, Hubert de Verneuil, Alain Taïeb, David R. Bickers & Frédéric Mazurier. (2010) Hypoxia-inducible factor-1α regulates the expression of nucleotide excision repair proteins in keratinocytes. Nucleic Acids Research 38:3, pages 797-809.
Crossref
Crossref
Elitsa Y. Dimova & Thomas Kietzmann. 2010. Transcription Factors. Transcription Factors
215
236
.
Raushan T. Kurmasheva, Hajime Hosoi, Ken Kikuchi & Peter J. Houghton. 2010. Molecularly Targeted Therapy for Childhood Cancer. Molecularly Targeted Therapy for Childhood Cancer
425
458
.
Yoon-Mi Lee, Ji-Hong Lim, Yang-Sook Chun, Hyo-Eun Moon, Myung Kyu Lee, L.Eric Huang & Jong-Wan Park. (2009) Nutlin-3, an Hdm2 antagonist, inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated inactivation of HIF-1α. Carcinogenesis 30:10, pages 1768-1775.
Crossref
Crossref
Armina A. Kazi, Kristin Happ Molitoris & Robert D. Koos. (2009) Estrogen Rapidly Activates the PI3K/AKT Pathway and Hypoxia-Inducible Factor 1 and Induces Vascular Endothelial Growth Factor A Expression in Luminal Epithelial Cells of the Rat Uterus1. Biology of Reproduction 81:2, pages 378-387.
Crossref
Crossref
Mitsuhiro Nakamura, Jason M. Bodily, Melanie Beglin, Satoru Kyo, Masaki Inoue & Laimonis A. Laimins. (2009) Hypoxia-specific stabilization of HIF-1alpha by human papillomaviruses. Virology 387:2, pages 442-448.
Crossref
Crossref
Hena Alam, Jennifer Weck, Evelyn Maizels, Youngkyu Park, Eun Jig Lee, Margaret Ashcroft & Mary Hunzicker-Dunn. (2009) Role of the Phosphatidylinositol-3-Kinase and Extracellular Regulated Kinase Pathways in the Induction of Hypoxia-Inducible Factor (HIF)-1 Activity and the HIF-1 Target Vascular Endothelial Growth Factor in Ovarian Granulosa Cells in Response to Follicle-Stimulating Hormone. Endocrinology 150:2, pages 915-928.
Crossref
Crossref
Niall S. Kenneth, Sharon Mudie, Patrick van Uden & Sonia Rocha. (2009) SWI/SNF Regulates the Cellular Response to Hypoxia. Journal of Biological Chemistry 284:7, pages 4123-4131.
Crossref
Crossref
Francesca Pistollato, Hui-Ling Chen, Brian R. Rood, Hui-Zhen Zhang, Domenico D'Avella, Luca Denaro, Marina Gardiman, Geertruy te Kronnie, Philip H. Schwartz, Elena Favaro, Stefano Indraccolo, Giuseppe Basso & David M. Panchision. (2009) Hypoxia and HIF1α Repress the Differentiative Effects of BMPs in High-Grade Glioma. Stem Cells 27:1, pages 7-17.
Crossref
Crossref
Sarah Jane Lunt, Naz Chaudary & Richard P. Hill. (2008) The tumor microenvironment and metastatic disease. Clinical & Experimental Metastasis 26:1, pages 19-34.
Crossref
Crossref
Alex Galanis, Aglaia Pappa, Antonis Giannakakis, Evripidis Lanitis, Denarda Dangaj & Raphael Sandaltzopoulos. (2008) Reactive oxygen species and HIF-1 signalling in cancer. Cancer Letters 266:1, pages 12-20.
Crossref
Crossref
Madhusudhanan Narasimhan, Rajiv Rose, Ramugounder Ramakrishnan, Jason A. Zell & Appu Rathinavelu. (2008) Identification of HDM2 as a regulator of VEGF expression in cancer cells. Life Sciences 82:25-26, pages 1231-1241.
Crossref
Crossref
Sung-Soo Park, Insoo Bae & Yong J. Lee. (2008) Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1α/2α is mediated through chelation of iron. Journal of Cellular Biochemistry 103:6, pages 1989-1998.
Crossref
Crossref
Stéphane Supiot, Richard P. Hill & Robert G. Bristow. (2008) Nutlin-3 radiosensitizes hypoxic prostate cancer cells independent of p53. Molecular Cancer Therapeutics 7:4, pages 993-999.
Crossref
Crossref
Veronica A. Carroll & Margaret Ashcroft. (2008) Regulation of Angiogenic Factors by HDM2 in Renal Cell Carcinoma. Cancer Research 68:2, pages 545-552.
Crossref
Crossref
Bu-Yeon KimHyungsoo KimEun-Jung ChoHong-Duk Youn. (2008) Nur77 upregulates HIF-α by inhibiting pVHL-mediated degradation. Experimental and Molecular Medicine 40:1, pages 71.
Crossref
Crossref
K M Sutton, S Hayat, N-M Chau, S Cook, J Pouyssegur, A Ahmed, N Perusinghe, R Le Floch, J Yang & M Ashcroft. (2007) Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1. Oncogene 26:27, pages 3920-3929.
Crossref
Crossref
David A. Rempe, Katherine M. Lelli, Grace Vangeison, Randall S. Johnson & Howard J. Federoff. (2007) In Cultured Astrocytes, p53 and MDM2 Do Not Alter Hypoxia-inducible Factor-1α Function Regardless of the Presence of DNA Damage. Journal of Biological Chemistry 282:22, pages 16187-16201.
Crossref
Crossref
Hamid Reza Rezvani, Sophie Dedieu, Sophie North, Francis Belloc, Rodrigue Rossignol, Thierry Letellier, Hubert de Verneuil, Alain Taïeb & Frédéric Mazurier. (2007) Hypoxia-inducible Factor-1α, a Key Factor in the Keratinocyte Response to UVB Exposure. Journal of Biological Chemistry 282:22, pages 16413-16422.
Crossref
Crossref
Julian J. Lum, Thi Bui, Michaela Gruber, John D. Gordan, Ralph J. DeBerardinis, Kelly L. Covello, M. Celeste Simon & Craig B. Thompson. (2007) The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes & Development 21:9, pages 1037-1049.
Crossref
Crossref
Sudipta Biswas, Manveen Kaur Gupta, Debasis Chattopadhyay & Chinmay K. Mukhopadhyay. (2007) Insulin-induced activation of hypoxia-inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase. American Journal of Physiology-Heart and Circulatory Physiology 292:2, pages H758-H766.
Crossref
Crossref
Gretchen A. LaRusch, Mark W. Jackson, James D. Dunbar, Robert S. Warren, David B. Donner & Lindsey D. Mayo. (2007) Nutlin3 Blocks Vascular Endothelial Growth Factor Induction by Preventing the Interaction between Hypoxia Inducible Factor 1α and Hdm2. Cancer Research 67:2, pages 450-454.
Crossref
Crossref
E H Gort, A J Groot, T L P Derks van de Ven, P van der Groep, I Verlaan, T van Laar, P J van Diest, E van der Wall & A Shvarts. (2006) Hypoxia-inducible factor-1α expression requires PI 3-kinase activity and correlates with Akt1 phosphorylation in invasive breast carcinomas. Oncogene 25:45, pages 6123-6127.
Crossref
Crossref
Koh Nakayama & Ze'ev Ronai. 2006. Protein Degradation. Protein Degradation
132
148
.
Veronica A. Carroll & Margaret Ashcroft. (2006) Role of Hypoxia-Inducible Factor (HIF)-1α versus HIF-2α in the Regulation of HIF Target Genes in Response to Hypoxia, Insulin-Like Growth Factor-I, or Loss of von Hippel-Lindau Function: Implications for Targeting the HIF Pathway. Cancer Research 66:12, pages 6264-6270.
Crossref
Crossref
Naoyasu Umeda, Shu Kachi, Hideo Akiyama, Grit Zahn, Doerte Vossmeyer, Roland Stragies & Peter A. Campochiaro. (2006)
Suppression and Regression of Choroidal Neovascularization by Systemic Administration of an α
5
β
1
Integrin Antagonist
. Molecular Pharmacology 69:6, pages 1820-1828.
Crossref
Crossref
Zhuo Zhang, Hui Wang, Mao Li, Elizabeth R Rayburn, Sudhir Agrawal & Ruiwen Zhang. (2005) Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway. Oncogene 24:48, pages 7238-7247.
Crossref
Crossref
Thomas Kietzmann & Agnes Görlach. (2005) Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression. Seminars in Cell & Developmental Biology 16:4-5, pages 474-486.
Crossref
Crossref
Anna-Liisa Nieminen, Suparna Qanungo, Elizabeth A. Schneider, Bing-Hua Jiang & Faton H. Agani. (2005) Mdm2 and HIF-1α interaction in tumor cells during hypoxia. Journal of Cellular Physiology 204:2, pages 364-369.
Crossref
Crossref
Julia I. Bárdos & Margaret Ashcroft. (2005) Negative and positive regulation of HIF-1: A complex network. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1755:2, pages 107-120.
Crossref
Crossref
Noan-Minh Chau, Paul Rogers, Wynne Aherne, Veronica Carroll, Ian Collins, Edward McDonald, Paul Workman & Margaret Ashcroft. (2005) Identification of Novel Small Molecule Inhibitors of Hypoxia-Inducible Factor-1 That Differentially Block Hypoxia-Inducible Factor-1 Activity and Hypoxia-Inducible Factor-1α Induction in Response to Hypoxic Stress and Growth Factors. Cancer Research 65:11, pages 4918-4928.
Crossref
Crossref
Jing Fang, Chang Xia, Zongxian Cao, Jenny Z. Zheng, Eddie Reed & Bing-Hua Jiang. (2005) Apigenin inhibits VEGF and HIF‐1 expression via PI3K/AKT/p70S6K1 and HDM2/p53 pathways. The FASEB Journal 19:3, pages 342-353.
Crossref
Crossref
Rolf Schwarzer, Daniel Tondera, Wolfgang Arnold, Klaus Giese, Anke Klippel & Jörg Kaufmann. (2004) REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase. Oncogene 24:7, pages 1138-1149.
Crossref
Crossref
Stefan Hiendleder, Valeri Zakhartchenko & Eckhard Wolf. (2005) Mitochondria and the success of somatic cell nuclear transfer cloning: from nuclear - mitochondrial interactions to mitochondrial complementation and mitochondrial DNA recombination. Reproduction, Fertility and Development 17:2, pages 69.
Crossref
Crossref
Sophie North, Michel Moenner & Andreas Bikfalvi. (2005) Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors. Cancer Letters 218:1, pages 1-14.
Crossref
Crossref
Young-Gun Yoo, Myeong Goo Yeo, Dae Kyong Kim, Hyunsung Park & Mi-Ock Lee. (2004) Novel Function of Orphan Nuclear Receptor Nur77 in Stabilizing Hypoxia-inducible Factor-1α. Journal of Biological Chemistry 279:51, pages 53365-53373.
Crossref
Crossref
Jianhua Feng, Rastislav Tamaskovic, Zhongzhou Yang, Derek P. Brazil, Adrian Merlo, Daniel Hess & Brian A. Hemmings. (2004) Stabilization of Mdm2 via Decreased Ubiquitination Is Mediated by Protein Kinase B/Akt-dependent Phosphorylation. Journal of Biological Chemistry 279:34, pages 35510-35517.
Crossref
Crossref
Kurt W. Kohn, Joseph Riss, Olga Aprelikova, John N. Weinstein, Yves Pommier & J. Carl Barrett. (2004) Properties of Switch-like Bioregulatory Networks Studied by Simulation of the Hypoxia Response Control System. Molecular Biology of the Cell 15:7, pages 3042-3052.
Crossref
Crossref