24
Views
92
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

The Brn-2 Transcription Factor Links Activated BRAF to Melanoma Proliferation

, , , , &
Pages 2923-2931 | Received 04 Dec 2003, Accepted 02 Jan 2004, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Heather M Shaw & Paul D Nathan. (2013) Vemurafenib in melanoma. Expert Review of Anticancer Therapy 13:5, pages 513-522.
Read now
Elise Bonvin, Paola Falletta, Heather Shaw, Veronique Delmas & Colin R. Goding. (2012) A Phosphatidylinositol 3-Kinase–Pax3 Axis Regulates Brn-2 Expression in Melanoma. Molecular and Cellular Biology 32:22, pages 4674-4683.
Read now
Irina Berlin, Laurence Denat, Anne-Lise Steunou, Isabel Puig, Delphine Champeval, Sophie Colombo, Karen Roberts, Elise Bonvin, Yveline Bourgeois, Irwin Davidson, Véronique Delmas, Laurence Nieto, Colin R. Goding & Lionel Larue. (2012) Phosphorylation of BRN2 Modulates Its Interaction with the Pax3 Promoter To Control Melanocyte Migration and Proliferation. Molecular and Cellular Biology 32:7, pages 1237-1247.
Read now
Guadalupe Camarero, Oleg Yu Tyrsin, Chaomei Xiang, Verena Pfeiffer, Sandra Pleiser, Stefan Wiese, Rudolf Götz & Ulf R. Rapp. (2006) Cortical Migration Defects in Mice Expressing A-RAF from the B-RAF Locus. Molecular and Cellular Biology 26:19, pages 7103-7115.
Read now
Jane Goodall, Silvia Martinozzi, Timothy J. Dexter, Delphine Champeval, Suzanne Carreira, Lionel Larue & Colin R. Goding. (2004) Brn-2 Expression Controls Melanoma Proliferation and Is Directly Regulated by β-Catenin. Molecular and Cellular Biology 24:7, pages 2915-2922.
Read now

Articles from other publishers (87)

Mitchell E. Fane, Yash Chhabra, Loredana Spoerri, Jacinta L. Simmons, Raquelle Ludwig, Elise Bonvin, Colin R. Goding, Richard A. Sturm, Glen M. Boyle, Nikolas K. Haass, Michael Piper & Aaron G. Smith. (2022) Reciprocal Regulation of BRN2 and NOTCH1/2 Signaling Synergistically Drives Melanoma Cell Migration and Invasion. Journal of Investigative Dermatology 142:7, pages 1845-1857.
Crossref
Ryan F. Leung, Ankita M. George, Enola M. Roussel, Maree C. Faux, Jeffrey T. Wigle & David D. Eisenstat. (2022) Genetic Regulation of Vertebrate Forebrain Development by Homeobox Genes. Frontiers in Neuroscience 16.
Crossref
Fan Huang, François Santinon, Raúl Ernesto Flores González & Sonia V. del Rincón. (2021) Melanoma Plasticity: Promoter of Metastasis and Resistance to Therapy. Frontiers in Oncology 11.
Crossref
Michael Hamm, Pierre Sohier, Valérie Petit, Jérémy H. Raymond, Véronique Delmas, Madeleine Le Coz, Franck Gesbert, Colin Kenny, Zackie Aktary, Marie Pouteaux, Florian Rambow, Alain Sarasin, Nisamanee Charoenchon, Alfonso Bellacosa, Luis Sanchez-del-Campo, Laura Mosteo, Martin Lauss, Dies Meijer, Eirikur Steingrimsson, Göran B. Jönsson, Robert A. Cornell, Irwin Davidson, Colin R. Goding & Lionel Larue. (2021) BRN2 is a non-canonical melanoma tumor-suppressor. Nature Communications 12:1.
Crossref
Rakshitha Pandulal Miskin, Janine S. A. Warren, Abibatou Ndoye, Lei Wu, John M. Lamar & C. Michael DiPersio. (2021) Integrin α3β1 Promotes Invasive and Metastatic Properties of Breast Cancer Cells through Induction of the Brn-2 Transcription Factor. Cancers 13:3, pages 480.
Crossref
Jacinta L. Simmons, Mei Fong Ng, Hannah M. Neuendorf & Glen M. Boyle. 2021. Anoikis. Anoikis 137 160 .
Romi Gupta, Radoslav Janostiak & Narendra Wajapeyee. (2020) Transcriptional regulators and alterations that drive melanoma initiation and progression. Oncogene 39:48, pages 7093-7105.
Crossref
Carly J. Pierce, Jacinta L. Simmons, Natasa Broit, Deshapriya Karunarathne, Mei Fong Ng & Glen M. Boyle. (2020) BRN2 expression increases anoikis resistance in melanoma. Oncogenesis 9:7.
Crossref
Arash Chitsazan, Duncan Lambie, Blake Ferguson, Herlina Y. Handoko, Brian Gabrielli, Graeme J. Walker & Glen M. Boyle. (2020) Unexpected High Levels of BRN2/POU3F2 Expression in Human Dermal Melanocytic Nevi. Journal of Investigative Dermatology 140:6, pages 1299-1302.e4.
Crossref
Colin R. Goding & Heinz Arnheiter. (2019) MITF—the first 25 years. Genes & Development 33:15-16, pages 983-1007.
Crossref
Fernanda F.M. da Cunha, Katia C.U. Mugnol, Filipe M. de Melo, Marta V.S.Q. Nascimento, Ricardo A. de Azevedo, Raquel T.S. Santos, Jéssica A. Magalhães, Danilo C. Miguel, Dayane B. Tada, Renato A. Mortara, Luiz R. Travassos & Denise C. Arruda. (2019) Peptide R18H from BRN2 Transcription Factor POU Domain Displays Antitumor Activity In Vitro and In Vivo and Induces Apoptosis in B16F10-Nex2 Cells. Anti-Cancer Agents in Medicinal Chemistry 19:3, pages 389-401.
Crossref
Katharine Herbert, Romuald Binet, Jean-Philippe Lambert, Pakavarin Louphrasitthiphol, Halime Kalkavan, Laura Sesma-Sanz, Carla Daniela Robles-Espinoza, Sovan Sarkar, Eda Suer, Sarah Andrews, Jagat Chauhan, Nicola D. Roberts, Mark R. Middleton, Anne-Claude Gingras, Jean-Yves Masson, Lionel Larue, Paola Falletta & Colin R. Goding. (2019) BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma. Genes & Development 33:5-6, pages 310-332.
Crossref
Mitchell E. Fane, Yash Chhabra, Aaron G. Smith & Richard A. Sturm. (2018) BRN 2, a POU erful driver of melanoma phenotype switching and metastasis . Pigment Cell & Melanoma Research 32:1, pages 9-24.
Crossref
Ken Noguchi, Toros A. Dincman, Annamarie C. Dalton, Breege V. Howley, Buckley J. McCall, Bidyut K. Mohanty & Philip H. Howe. (2018) Interleukin-like EMT inducer (ILEI) promotes melanoma invasiveness and is transcriptionally up-regulated by upstream stimulatory factor-1 (USF-1). Journal of Biological Chemistry 293:29, pages 11401-11414.
Crossref
Wei Song, Yimin Sun, Jie Lin & Xiaoqin Bi. (2017) Current research on head and neck cancer-associated long noncoding RNAs. Oncotarget 9:1, pages 1403-1425.
Crossref
Jacinta L. Simmons, Carly J. Pierce, Fares Al-Ejeh & Glen M. Boyle. (2017) MITF and BRN2 contribute to metastatic growth after dissemination of melanoma. Scientific Reports 7:1.
Crossref
Min Keun Chee, Seong Kyeong Jo, Kyung Cheol Sohn, Chang Deok Kim, Jeung-Hoon Lee & Young Ho Lee. (2017) Effects of Brn2 overexpression on eccrine sweat gland development in the mouse paw. Biochemical and Biophysical Research Communications 490:3, pages 901-905.
Crossref
Wing Tak Wong, Gianfranco Matrone, XiaoYu Tian, Simion Alin Tomoiaga, Kin Fai Au, Shu Meng, Sayumi Yamazoe, Daniel Sieveking, Kaifu Chen, David M Burns, James K Chen, Helen M Blau & John P Cooke. (2017) Discovery of novel determinants of endothelial lineage using chimeric heterokaryons. eLife 6.
Crossref
Esther Diana Rossi, Maurizio Martini, Tommaso Bizzarro, Fernando Schmitt, Adhemar Longatto-Filho & Luigi Maria Larocca. (2016) Somatic mutations in solid tumors: a spectrum at the service of diagnostic armamentarium or an indecipherable puzzle? The morphological eyes looking for BRAF and somatic molecular detections on cyto-histological samples . Oncotarget 8:2, pages 3746-3760.
Crossref
Jennifer L. Bishop, Daksh Thaper, Sepideh Vahid, Alastair Davies, Kirsi Ketola, Hidetoshi Kuruma, Randy Jama, Ka Mun Nip, Arkhjamil Angeles, Fraser Johnson, Alexander W. Wyatt, Ladan Fazli, Martin E. Gleave, Dong Lin, Mark A. Rubin, Colin C. Collins, Yuzhuo Wang, Himisha Beltran & Amina Zoubeidi. (2017) The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate Cancer. Cancer Discovery 7:1, pages 54-71.
Crossref
Yann Cheli, Eric Lau & Ze’ev A. Ronai. 2017. Melanoma Development. Melanoma Development 177 207 .
Ivan Evangelista do Vale Coelho, Denise Costa Arruda & Alex Gutterres Taranto. (2016) In silico studies of the interaction between BRN2 protein and MORE DNA. Journal of Molecular Modeling 22:9.
Crossref
Hung Chen, Yi Lee, Huei Chen, Chia Yeh, Pin Chueh & Yi-Mei Lin. (2016) Capsaicin Inhibited Aggressive Phenotypes through Downregulation of Tumor-Associated NADH Oxidase (tNOX) by POU Domain Transcription Factor POU3F2. Molecules 21:6, pages 733.
Crossref
Dong Wang, Junyun Wang, Nan Ding, Yongjun Li, Yaran Yang, Xiangdong Fang & Hua Zhao. (2016) MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation. Biochemical and Biophysical Research Communications 473:4, pages 959-965.
Crossref
Lekshmi R. Nath, S. N. Kumar, Arya A. Das, Bala Nambisan, A. Shabna, Chellapan Mohandas & Ruby John Anto. (2016) In Vitro Evaluation of the Antioxidant, 3,5-Dihydroxy-4-ethyl-trans-stilbene (DETS) Isolated from Bacillus cereus as a Potent Candidate against Malignant Melanoma. Frontiers in Microbiology 7.
Crossref
Kevin M. Poindexter, Susanne Matthew, Ida Aronchik & Gary L. Firestone. (2016) Cooperative antiproliferative signaling by aspirin and indole-3-carbinol targets microphthalmia-associated transcription factor gene expression and promoter activity in human melanoma cells. Cell Biology and Toxicology 32:2, pages 103-119.
Crossref
Motoshi Nagao, Toru Ogata, Yasuhiro Sawada & Yukiko Gotoh. (2016) Zbtb20 promotes astrocytogenesis during neocortical development. Nature Communications 7:1.
Crossref
Simone Ribero, Caterina Longo, Dan Glass, Paul Nathan & Veronique Bataille. (2016) What Is New in Melanoma Genetics and Treatment?. Dermatology 232:3, pages 259-264.
Crossref
Junyun Wang, Nan Ding, Yongjun Li, Hua Cheng, Dong Wang, Qiong Yang, Youhui Deng, Yaran Yang, Yanming Li, Xiuyan Ruan, Fang Xie, Hua Zhao & Xiangdong Fang. (2015) Insulin-like growth factor binding protein 5 (IGFBP5) functions as a tumor suppressor in human melanoma cells. Oncotarget 6:24, pages 20636-20649.
Crossref
Claudia Wellbrock & Imanol Arozarena. (2015) Microphthalmia‐associated transcription factor in melanoma development and MAP ‐kinase pathway targeted therapy . Pigment Cell & Melanoma Research 28:4, pages 390-406.
Crossref
Jiri Vachtenheim & Lubica Ondrušová. (2015) Microphthalmia-associated transcription factor expression levels in melanoma cells contribute to cell invasion and proliferation. Experimental Dermatology 24:7, pages 481-484.
Crossref
Jayesh Antony, Minakshi Saikia, Vinod. V, Lekshmi. R. Nath, Mohana Rao Katiki, M.S.R. Murty, Anju Paul, Shabna A, Harsha Chandran, Sophia Margaret Joseph, Nishanth Kumar. S, Elizabeth Jayex Panakkal, Sriramya I. V, Sridivya I. V, Sophia Ran, Sankar S, Easwary Rajan & Ruby John Anto. (2015) DW-F5: A novel formulation against malignant melanoma from Wrightia tinctoria. Scientific Reports 5:1.
Crossref
Estibaliz Alegre, Miguel Sammamed, Sara Fernández-Landázuri, Leyre Zubiri & Álvaro González. 2015. 47 89 .
Aanchal Mehrotra, Srinivas Vinod Saladi, Archit R. Trivedi, Shweta Aras, Huiling Qi, Ashika Jayanthy, Vijayasaradhi Setaluri & Ivana L. de la Serna. (2014) Modulation of BRAHMA expression by the mitogen-activated protein kinase/extracellular signal regulated kinase pathway is associated with changes in melanoma proliferation. Archives of Biochemistry and Biophysics 563, pages 125-135.
Crossref
Emanuela Bastonini, Magdalena Jeznach, Megan Field, Katarzyna Juszczyk, Emily Corfield, Mehrnoush Dezfouli, Nurfilza Ahmat, Aimee Smith, Howard Womersley, Philip Jordan, Aroul Ramadass, Alexandre Akoulitchev & Colin R. Goding. (2014) Chromatin barcodes as biomarkers for melanoma. Pigment Cell & Melanoma Research 27:5, pages 788-800.
Crossref
Eun-Gyung Cho, Bum-Ho Bin, Hyunjung Choi, Phil June Park, Hak Hee Kang & Tae Ryong Lee. (2014) Novel method for isolating human melanoblasts from keratinocyte culture. Pigment Cell & Melanoma Research 27:3, pages 489-494.
Crossref
Robert Besch & Carola Berking. (2014) POU transcription factors in melanocytes and melanoma. European Journal of Cell Biology 93:1-2, pages 55-60.
Crossref
Ewa Aladowicz, Leda Ferro, Giulio Cesare Vitali, Elisabetta Venditti, Lorenzo Fornasari & Luisa Lanfrancone. (2013) Molecular networks in melanoma invasion and metastasis. Future Oncology 9:5, pages 713-726.
Crossref
Jun Ishii, Hanako Sato, Masashi Sakaeda, Yukiko Shishido-Hara, Chie Hiramatsu, Hiroshi Kamma, Hiroaki Shimoyamada, Masachika Fujiwara, Tetsuya Endo, Ichiro Aoki & Takuya Yazawa. (2013) POU domain transcription factor BRN2 is crucial for expression of ASCL1, ND1 and neuroendocrine marker molecules and cell growth in small cell lung cancer. Pathology International 63:3, pages 158-168.
Crossref
Dana Koludrovic & Irwin Davidson. (2013) MITF, the Janus transcription factor of melanoma. Future Oncology 9:2, pages 235-244.
Crossref
Jose L. Orgaz & Victoria Sanz-Moreno. (2013) Emerging molecular targets in melanoma invasion and metastasis. Pigment Cell & Melanoma Research 26:1, pages 39-57.
Crossref
Lisa Ellmann, Manjunath B Joshi, Therese J Resink, Anja K Bosserhoff & Silke Kuphal. (2012) BRN2 is a transcriptional repressor of CDH13 (T-cadherin) in melanoma cells. Laboratory Investigation 92:12, pages 1788-1800.
Crossref
Maria Wehbe, Saïdi M. Soudja, Amandine Mas, Lionel Chasson, Rodolphe Guinamard, Céline Powis de Tenbossche, Grégory Verdeil, Benoît Van den Eynde & Anne-Marie Schmitt-Verhulst. (2012) Epithelial-Mesenchymal-Transition-Like and TGFβ Pathways Associated with Autochthonous Inflammatory Melanoma Development in Mice. PLoS ONE 7:11, pages e49419.
Crossref
Nathan V. Lee, Maruja E. Lira, Adam Pavlicek, Jingjing Ye, Dana Buckman, Shubha Bagrodia, Sreesha P. Srinivasa, Yongjun Zhao, Samuel Aparicio, Paul A. Rejto, James G. Christensen & Keith A. Ching. (2012) A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation. PLoS ONE 7:6, pages e39653.
Crossref
Mizue Terai, Masumi Eto, Garbo D. Young, David Berd, Michael J. Mastrangelo, Yutaka Tamura, Kenichi Harigaya & Takami Sato. (2011) Interleukin 6 mediates production of interleukin 10 in metastatic melanoma. Cancer Immunology, Immunotherapy 61:2, pages 145-155.
Crossref
Ichiro Yajima, Mayuko Y. Kumasaka, Nguyen Dinh Thang, Yuji Goto, Kozue Takeda, Osamu Yamanoshita, Machiko Iida, Nobutaka Ohgami, Haruka Tamura, Yoshiyuki Kawamoto & Masashi Kato. (2012) RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy. Dermatology Research and Practice 2012, pages 1-5.
Crossref
Paolo Antonio Ascierto, Maria Libera Ascierto, Mariaelena Capone, Zendee Elaba, Michael J. Murphy & Giuseppe Palmieri. 2012. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma. Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma 19 37 .
Takami Sato, Mizue Terai, Yutaka Tamura, Vitali Alexeev, Michael J. Mastrangelo & Senthamil R. Selvan. (2011) Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy. Immunologic Research 51:2-3, pages 170-182.
Crossref
Pablo Lopez-Bergami. (2011) The role of mitogen- and stress-activated protein kinase pathways in melanoma. Pigment Cell & Melanoma Research 24:5, pages 902-921.
Crossref
Glen M. Boyle, Susan L. Woods, Vanessa F. Bonazzi, Mitchell S. Stark, Elke Hacker, Lauren G. Aoude, Ken Dutton-Regester, Anthony L. Cook, Richard A. Sturm & Nicholas K. Hayward. (2011) Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor. Pigment Cell & Melanoma Research 24:3, pages 525-537.
Crossref
Aaron G. Smith, Wen Lim, Michael Pearen, George E. O. Muscat & Richard A. Sturm. (2011) Regulation of NR4A nuclear receptor expression by oncogenic BRAF in melanoma cells. Pigment Cell & Melanoma Research 24:3, pages 551-563.
Crossref
Sandy Giuliano, Mickaël Ohanna, Robert Ballotti & Corine Bertolotto. (2011) Advances in melanoma senescence and potential clinical application. Pigment Cell & Melanoma Research 24:2, pages 295-308.
Crossref
Alvaro C. Laga, Qian Zhan, Carsten Weishaupt, Jie Ma, Markus H. Frank & George F. Murphy. (2011) SOX2 and nestin expression in human melanoma: an immunohistochemical and experimental study. Experimental Dermatology 20:4, pages 339-345.
Crossref
Keith T. Flaherty. (2011) Taking stock of translational research in melanoma at the 2010 Society for Melanoma Research Congress. Pigment Cell & Melanoma Research 24:1, pages 107-109.
Crossref
Imanol Arozarena, Berta Sanchez-Laorden, Leisl Packer, Cristina Hidalgo-Carcedo, Robert Hayward, Amaya Viros, Erik Sahai & Richard Marais. (2011) Oncogenic BRAF Induces Melanoma Cell Invasion by Downregulating the cGMP-Specific Phosphodiesterase PDE5A. Cancer Cell 19:1, pages 45-57.
Crossref
Eric Lau & Ze’ev A. Ronai. 2011. Melanoma Development. Melanoma Development 137 163 .
Keith S. Hoek & Colin R. Goding. (2010) Cancer stem cells versus phenotype-switching in melanoma. Pigment Cell & Melanoma Research 23:6, pages 746-759.
Crossref
Ge Shi, Kyung-Cheol Sohn, Dae-Kyoung Choi, Yu-Jin Kim, Seong-Jin Kim, Bai-Sheng Ou, Yong-Jun Piao, Young Ho Lee, Tae-Jin Yoon, Young Lee, Young-Joon Seo, Chang Deok Kim & Jeung-Hoon Lee. (2010) Brn2 Is a Transcription Factor Regulating Keratinocyte Differentiation with a Possible Role in the Pathogenesis of Lichen Planus. PLoS ONE 5:10, pages e13216.
Crossref
Renato M. Bakos, Tanja Maier, Robert Besch, Dominik S. Mestel, Thomas Ruzicka, Richard A. Sturm & Carola Berking. (2009) Nestin and SOX9 and SOX10 transcription factors are coexpressed in melanoma. Experimental Dermatology 19:8, pages e89-e94.
Crossref
Dominique Kobi, Anne-Lise Steunou, Doulaye Dembélé, Stéphanie Legras, Lionel Larue, Laurence Nieto & Irwin Davidson. (2010) Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene. Pigment Cell & Melanoma Research 23:3, pages 404-418.
Crossref
M. Lynn Lamoreux, Véronique Delmas, Lionel Larue & Dorothy C. Bennett. 2010. The Colors of Mice. The Colors of Mice 243 285 .
Ethan V. Abel & Andrew E. Aplin. (2010) FOXD3 Is a Mutant B-RAF–Regulated Inhibitor of G1-S Progression in Melanoma Cells. Cancer Research 70:7, pages 2891-2900.
Crossref
Leisl M Packer, Philip East, Jorge S Reis-Filho & Richard Marais. (2009) Identification of direct transcriptional targets of V600E BRAF/MEK signalling in melanoma . Pigment Cell & Melanoma Research 22:6, pages 785-798.
Crossref
Sophie Pinner, Peter Jordan, Kirsty Sharrock, Laura Bazley, Lucy Collinson, Richard Marais, Elise Bonvin, Colin Goding & Erik Sahai. (2009) Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination. Cancer Research 69:20, pages 7969-7977.
Crossref
Anna Flammiger, Robert Besch, Anthony L. Cook, Tanja Maier, Richard A. Sturm & Carola Berking. (2009) SOX9 and SOX10 but Not BRN2 Are Required for Nestin Expression in Human Melanoma Cells. Journal of Investigative Dermatology 129:4, pages 945-953.
Crossref
William M. Old, John B. Shabb, Stephane Houel, Hong Wang, Kasey L. Couts, Chia-yu Yen, Elizabeth S. Litman, Carrie H. Croy, Karen Meyer-Arendt, Jose G. Miranda, Robert A. Brown, Eric S. Witze, Rebecca E. Schweppe, Katheryn A. Resing & Natalie G. Ahn. (2009) Functional Proteomics Identifies Targets of Phosphorylation by B-Raf Signaling in Melanoma. Molecular Cell 34:1, pages 115-131.
Crossref
Aaron G. Smith, Kimberley A. Beaumont, Darren J. Smit, Amy E. Thurber, Anthony L. Cook, Glen M. Boyle, Peter G. Parsons, Richard A. Sturm & George E.O. Muscat. (2009) PPARγ agonists attenuate proliferation and modulate Wnt/β-catenin signalling in melanoma cells. The International Journal of Biochemistry & Cell Biology 41:4, pages 844-852.
Crossref
Béatrice Cabos-Siguier, Anne-Lise Steunou, Gérard Joseph, Robert Alazard, Manuelle Ducoux-Petit, Laurence Nieto, Bernard Monsarrat, Monique Erard & Eric Clottes. (2009) Expression and purification of human full-length N Oct-3, a transcription factor involved in melanoma growth. Protein Expression and Purification 64:1, pages 39-46.
Crossref
Jennifer D. Kubic, Kacey P. Young, Rebecca S. Plummer, Anton E. Ludvik & Deborah Lang. (2008) Pigmentation PAX-ways: the role of Pax3 in melanogenesis, melanocyte stem cell maintenance, and disease. Pigment Cell & Melanoma Research 21:6, pages 627-645.
Crossref
Anthony L. Cook & Richard A. Sturm. (2008) POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis. Pigment Cell & Melanoma Research 21:6, pages 611-626.
Crossref
Jane Goodall, Suzanne Carreira, Laurence Denat, Dominique Kobi, Irwin Davidson, Paolo Nuciforo, Richard A. Sturm, Lionel Larue & Colin R. Goding. (2008) Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor–Negative Melanoma Cells. Cancer Research 68:19, pages 7788-7794.
Crossref
Naomi M. Richmond-Sinclair, Eva Lee, Margaret C. Cummings, Richard Williamson, H. Konrad Muller, Adèle C. Green, Nicholas K. Hayward & David C. Whiteman. (2008) Histologic and epidemiologic correlates of P-MAPK, Brn-2, pRb, p53, and p16 immunostaining in cutaneous melanomas. Melanoma Research 18:5, pages 336-345.
Crossref
Claudia Wellbrock, Sareena Rana, Hugh Paterson, Helen Pickersgill, Thijn Brummelkamp & Richard Marais. (2008) Oncogenic BRAF Regulates Melanoma Proliferation through the Lineage Specific Factor MITF. PLoS ONE 3:7, pages e2734.
Crossref
C Michaloglou, L C W Vredeveld, W J Mooi & D S Peeper. (2007) BRAFE600 in benign and malignant human tumours. Oncogene 27:7, pages 877-895.
Crossref
Heejei Yoon, Huiling He, Rebecca Nagy, Ramana Davuluri, Saul Suster, Daniel Schoenberg, Natalia Pellegata & Albert de la Chapelle. (2007) Identification of a novel noncoding RNA gene, NAMA , that is downregulated in papillary thyroid carcinoma with BRAF mutation and associated with growth arrest . International Journal of Cancer 121:4, pages 767-775.
Crossref
Robert Alazard, Lionel Mourey, Christine Ebel, Peter V. Konarev, Maxim V. Petoukhov, Dmitri I. Svergun & Monique Erard. (2007) Fine-tuning of intrinsic N-Oct-3 POU domain allostery by regulatory DNA targets. Nucleic Acids Research 35:13, pages 4420-4432.
Crossref
Laurence Nieto, Gérard Joseph, Alexandre Stella, Pauline Henri, Odile Burlet-Schiltz, Bernard Monsarrat, Eric Clottes & Monique Erard. (2007) Differential Effects of Phosphorylation on DNA Binding Properties of N Oct-3 Are Dictated by Protein/DNA Complex Structures. Journal of Molecular Biology 370:4, pages 687-700.
Crossref
Vanessa Gray-Schopfer, Claudia Wellbrock & Richard Marais. (2007) Melanoma biology and new targeted therapy. Nature 445:7130, pages 851-857.
Crossref
J A Ellerhorst, S Ekmekcioglu, M K Johnson, C P Cooke, M M Johnson & E A Grimm. (2006) Regulation of iNOS by the p44/42 mitogen-activated protein kinase pathway in human melanoma. Oncogene 25:28, pages 3956-3962.
Crossref
Nancy E. Thomas. (2006) BRAF somatic mutations in malignant melanoma and melanocytic naevi. Melanoma Research 16:2, pages 97-103.
Crossref
Anthony L. Cook, Glen M. Boyle, J. Helen Leonard, Peter G. Parsons & Richard A. Sturm. 2006. From Melanocytes to Melanoma. From Melanocytes to Melanoma 149 167 .
Claudia Wellbrock. 2006. From Melanocytes to Melanoma. From Melanocytes to Melanoma 247 263 .
Birgit Schittek, Tobias Sinnberg & Friedegund Meier. 2006. Management des Melanoms. Management des Melanoms 13 30 .
Jade Homsi, Mohammed Kashani-SabetJane L. Messina & Adil Daud. (2017) Cutaneous Melanoma: Prognostic Factors. Cancer Control 12:4, pages 223-229.
Crossref
Bi-ke Zhu & Steven C. Pruitt. (2005) Determination of transcription factors and their possible roles in the regulation of Pax3 gene expression in the mouse B16 F1 melanoma cell line. Melanoma Research 15:5, pages 363-373.
Crossref
Anthony L. Cook, Aaron G. Smith, Darren J. Smit, J. Helen Leonard & Richard A. Sturm. (2005) Co-expression of SOX9 and SOX10 during melanocytic differentiation in vitro. Experimental Cell Research 308:1, pages 222-235.
Crossref
Keith W. Vance & Colin R. Goding. (2004) The Transcription Network Regulating Melanocyte Development and Melanoma. Pigment Cell Research 17:4, pages 318-325.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.