Advanced search
Publication Cover
Molecular and Cellular Biology Volume 25, 2005 - Issue 12
Submit an article Journal homepage
130
Views
336
CrossRef citations to date
0
Altmetric
Mammalian Genetic Models with Minimal or Complex Phenotypes

MafA Is a Key Regulator of Glucose-Stimulated Insulin Secretion

Chuan Zhang1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Takashi Moriguchi1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan;2 University of Michigan Medical School, Ann Arbor, Michigan48109-0616
,
Miwako Kajihara1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Ritsuko Esaki1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Ayako Harada1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Homare Shimohata1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Hisashi Oishi1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Michito Hamada1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Naoki Morito1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Kazuteru Hasegawa1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
Takashi Kudo1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, Japan
,
James Douglas Engel2 University of Michigan Medical School, Ann Arbor, Michigan48109-0616
,
Masayuki Yamamoto3 Center for Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8577, Japan
&
Satoru Takahashi1 Institute of Basic Medical Sciences and Laboratory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba305-8575, JapanCorrespondence[email protected]
 show all
Pages 4969-4976 | Received 01 Oct 2004, Accepted 22 Mar 2005, Published online: 27 Mar 2023

Citations (336)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (13)

Melissa T. Adams & Barak Blum. (2022) Determinants and dynamics of pancreatic islet architecture. Islets 14:1, pages 82-100.
Read now
Gulibaikelamu Xiafukaiti, Shayida Maimaiti, Kiyohito Ogata, Akihiro Kuno, Takashi Kudo, Hossam H. Shawki, Hisashi Oishi & Satoru Takahashi. (2019) MafB Is Important for Pancreatic β-Cell Maintenance under a MafA-Deficient Condition. Molecular and Cellular Biology 39:17.
Read now
Megumi C. Katoh, Yunshin Jung, Chioma M. Ugboma, Miki Shimbo, Akihiro Kuno, Walaa A. Basha, Takashi Kudo, Hisashi Oishi & Satoru Takahashi. (2018) MafB Is Critical for Glucagon Production and Secretion in Mouse Pancreatic α Cells In Vivo. Molecular and Cellular Biology 38:8.
Read now
Hideaki Kaneto. (2016) Pancreatic β-cell failure in type 2 diabetes mellitus. Expert Review of Endocrinology & Metabolism 11:1, pages 1-2.
Read now
Reshmi Dassaye, Strini Naidoo & Marlon E. Cerf. (2016) Transcription factor regulation of pancreatic organogenesis, differentiation and maturation. Islets 8:1, pages 13-34.
Read now
Han-Hung Huang & Lisa Stehno-Bittel. (2015) Differences in insulin biosynthesis pathway between small and large islets do not correspond to insulin secretion. Islets 7:5.
Read now
Uma Gunasekaran, Courtney W. Hudgens, Brian T. Wright, Matthew F. Maulis & Maureen Gannon. (2012) Differential regulation of embryonic and adult β cell replication. Cell Cycle 11:13, pages 2431-2442.
Read now
Jingxuan Liu, Erik R. Walp & Catherine Lee May. (2012) Elevation of transcription factor Islet-1 levels in vivo increases β-cell function but not β-cell mass. Islets 4:3, pages 199-206.
Read now
Jeffrey C. Raum, Chad S. Hunter, Isabella Artner, Eva Henderson, Min Guo, Lynda Elghazi, Beatriz Sosa-Pineda, Takeshi Ogihara, Raghavendra G. Mirmira, Lori Sussel & Roland Stein. (2010) Islet β-Cell-Specific MafA Transcription Requires the 5′-Flanking Conserved Region 3 Control Domain. Molecular and Cellular Biology 30:17, pages 4234-4244.
Read now
Takeshi Miyatsuka, Taka-aki Matsuoka & Hideaki Kaneto. (2008) Transcription factors as therapeutic targets for diabetes. Expert Opinion on Therapeutic Targets 12:11, pages 1431-1442.
Read now
Song-iee Han, Shinsaku Aramata, Kunio Yasuda & Kohsuke Kataoka. (2007) MafA Stability in Pancreatic β Cells Is Regulated by Glucose and Is Dependent on Its Constitutive Phosphorylation at Multiple Sites by Glycogen Synthase Kinase 3. Molecular and Cellular Biology 27:19, pages 6593-6605.
Read now
Jeffrey C. Raum, Kevin Gerrish, Isabella Artner, Eva Henderson, Min Guo, Lori Sussel, Jonathan C. Schisler, Christopher B. Newgard & Roland Stein. (2006) FoxA2, Nkx2.2, and PDX-1 Regulate Islet β-Cell-Specific mafA Expression through Conserved Sequences Located between Base Pairs −8118 and −7750 Upstream from the Transcription Start Site. Molecular and Cellular Biology 26:15, pages 5735-5743.
Read now
Takashi Moriguchi, Michito Hamada, Naoki Morito, Tsumoru Terunuma, Kazuteru Hasegawa, Chuan Zhang, Tomomasa Yokomizo, Ritsuko Esaki, Etsushi Kuroda, Keigyou Yoh, Takashi Kudo, Michio Nagata, David R. Greaves, James Douglas Engel, Masayuki Yamamoto & Satoru Takahashi. (2006) MafB Is Essential for Renal Development and F4/80 Expression in Macrophages. Molecular and Cellular Biology 26:15, pages 5715-5727.
Read now

Articles from other publishers (323)

Haiqing Bu, Zhijia Li, Yingying Lu, Zhiyao Zhuang, Yongqi Zhen & Lan Zhang. (2023) Deciphering the multifunctional role of dual leucine zipper kinase (DLK) and its therapeutic potential in disease. European Journal of Medicinal Chemistry 255, pages 115404.
Crossref
Xinzhi Li, Ying Yang, Zhenzhi Li, Yuqin Wang, Jingting Qiao & Zheng Chen. (2023) Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice. Diabetologia 66:6, pages 1084-1096.
Crossref
Rahul Sharma, Sujay K. Maity, Partha Chakrabarti, Madhumohan R. Katika, Satyamoorthy Kapettu, Kishore V. L. Parsa & Parimal Misra. (2023) PIMT Controls Insulin Synthesis and Secretion through PDX1. International Journal of Molecular Sciences 24:9, pages 8084.
Crossref
Shunya Sadaki, Ryo Fujita, Takuto Hayashi, Ayano Nakamura, Yui Okamura, Sayaka Fuseya, Michito Hamada, Eiji Warabi, Akihiro Kuno, Akiko Ishii, Masafumi Muratani, Risa Okada, Dai Shiba, Takashi Kudo, Shin’ichi Takeda & Satoru Takahashi. (2023) Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination. Cell Reports 42:4, pages 112289.
Crossref
Rania Saeed, Abdul Khader Mohammed, Sarra E. Saleh, Khaled M. Aboshanab, Mohammad M. Aboulwafa & Jalal Taneera. (2023) Expression Silencing of Mitogen-Activated Protein Kinase 8 Interacting Protein-1 Conferred Its Role in Pancreatic β-Cell Physiology and Insulin Secretion. Metabolites 13:2, pages 307.
Crossref
Yalan Deng, Liqing Lu, Huajun Zhang, Ying Fu, Ting Liu & Yongheng Chen. (2023) The role and regulation of Maf proteins in cancer. Biomarker Research 11:1.
Crossref
Mohammad G MohammadRania SaeedAbdul Khader MohammedAnila KhaliqueMohamad HamadWaseem El-HuneidiMawieh Hamad & Jalal Taneera. (2023) GDF15 plays a critical role in insulin secretion in INS-1 cells and human pancreatic islets . Experimental Biology and Medicine 248:4, pages 339-349.
Crossref
Angelique Cercillieux, Joanna Ratajczak, Magali Joffraud, José Luis Sanchez-Garcia, Guillaume Jacot, Alix Zollinger, Sylviane Métairon, Judith Giroud-Gerbetant, Marie Rumpler, Eleonora Ciarlo, Miriam Valera-Alberni, Audrey Sambeat & Carles Canto. (2022) Nicotinamide riboside kinase 1 protects against diet and age-induced pancreatic β-cell failure. Molecular Metabolism 66, pages 101605.
Crossref
Jayron J. Habibe, Maria P. Clemente-Olivo, Torsten P. M. Scheithauer, Elena Rampanelli, Hilde Herrema, Mariska Vos, Arnout Mieremet, Max Nieuwdorp, Daniel H. van Raalte, Etto C. Eringa & Carlie J. M. de Vries. (2022) Glucose-mediated insulin secretion is improved in FHL2-deficient mice and elevated FHL2 expression in humans is associated with type 2 diabetes. Diabetologia 65:10, pages 1721-1733.
Crossref
Bodo C. Melnik & Gerd Schmitz. (2022) Milk Exosomal microRNAs: Postnatal Promoters of β Cell Proliferation but Potential Inducers of β Cell De-Differentiation in Adult Life. International Journal of Molecular Sciences 23:19, pages 11503.
Crossref
Chien-Wen Chen, Bo-Jhih Guan, Mohammed R. Alzahrani, Zhaofeng Gao, Long Gao, Syrena Bracey, Jing Wu, Cheikh A. Mbow, Raul Jobava, Leena Haataja, Ajay H. Zalavadia, Ashleigh E. Schaffer, Hugo Lee, Thomas LaFramboise, Ilya Bederman, Peter Arvan, Clayton E. Mathews, Ivan C. Gerling, Klaus H. Kaestner, Boaz Tirosh, Feyza Engin & Maria Hatzoglou. (2022) Adaptation to chronic ER stress enforces pancreatic β-cell plasticity. Nature Communications 13:1.
Crossref
Wenwen Jin & Wei Jiang. (2022) Stepwise differentiation of functional pancreatic β cells from human pluripotent stem cells. Cell Regeneration 11:1.
Crossref
Jennifer S Stancill, Polly A Hansen, Angela J Mathison, Edward E Schmidt & John A Corbett. (2022) Deletion of Thioredoxin Reductase Disrupts Redox Homeostasis and Impairs β-Cell Function. Function 3:4.
Crossref
Nan Wu, Weihua Jin, Yuchen Zhao, Hong Wang, Sunyue He, Wenjing Zhang & Jiaqiang Zhou. (2022) Sulfated Fucogalactan From Laminaria Japonica Ameliorates β-Cell Failure by Attenuating Mitochondrial Dysfunction via SIRT1–PGC1-α Signaling Pathway Activation. Frontiers in Endocrinology 13.
Crossref
Alexandra L. G. Mahoney, Najah T. Nassif, Bronwyn A. O’Brien & Ann M. Simpson. (2022) Pancreatic Transdifferentiation Using β-Cell Transcription Factors for Type 1 Diabetes Treatment. Cells 11:14, pages 2145.
Crossref
Laure Lecoin, Bowen Dempsey, Alexandra Garancher, Steeve Bourane, Pierre-Louis Ruffault, Marie-Pierre Morin-Surun, Nathalie Rocques, Martyn Goulding, Alain Eychène, Celio Pouponnot, Gilles Fortin & Jean Champagnat. (2022) Mafa-dependent GABAergic activity promotes mouse neonatal apneas. Nature Communications 13:1.
Crossref
Han-yu Yang, Ming Liu, Yun Sheng, Liang Zhu, Meng-meng Jin, Tian-xin Jiang, Lu Yang, Pei-hua Liu, Xiao-dong Liu & Li Liu. (2021) All-trans retinoic acid impairs glucose-stimulated insulin secretion by activating the RXR/SREBP-1c/UCP2 pathway. Acta Pharmacologica Sinica 43:6, pages 1441-1452.
Crossref
Eran Yanowski, Nancy S. Yacovzada, Eyal David, Amir Giladi, Diego Jaitin, Lydia Farack, Adi Egozi, Danny Ben-Zvi, Shalev Itzkovitz, Ido Amit & Eran Hornstein. (2022) Physically interacting beta-delta pairs in the regenerating pancreas revealed by single-cell sequencing. Molecular Metabolism 60, pages 101467.
Crossref
Ching-Chung Liang, Steven W Shaw, Yung-Hsin Huang & Tsong-Hai Lee. (2022) Human amniotic fluid stem cell therapy can help regain bladder function in type 2 diabetic rats. World Journal of Stem Cells 14:5, pages 330-346.
Crossref
Reinaldo Sousa Dos Santos, Regla María Medina-Gali, Ignacio Babiloni-Chust, Laura Marroqui & Angel Nadal. (2022) In Vitro Assays to Identify Metabolism-Disrupting Chemicals with Diabetogenic Activity in a Human Pancreatic β-Cell Model. International Journal of Molecular Sciences 23:9, pages 5040.
Crossref
Wataru Nishimura, Hiroaki Iwasa & Munkhtuya Tumurkhuu. (2022) Role of the Transcription Factor MAFA in the Maintenance of Pancreatic β-Cells. International Journal of Molecular Sciences 23:9, pages 4478.
Crossref
Christian Fottner, Stefanie Sollfrank, Mursal Ghiasi, Anke Adenaeuer, Thomas Musholt, Arno Schad, Matthias Miederer, Simin Schadmand-Fischer, Matthias M. Weber, Karl J. Lackner & Heidi Rossmann. (2022) Second MAFA Variant Causing a Phosphorylation Defect in the Transactivation Domain and Familial Insulinomatosis. Cancers 14:7, pages 1798.
Crossref
Ziyin Zhang, Yue Gao & Zhuo-Xian Meng. (2022) Transcriptional control of pancreatic β-cell identity and plasticity during the pathogenesis of type 2 diabetes. Journal of Genetics and Genomics 49:4, pages 316-328.
Crossref
Hideaki Kaneto, Tomohiko Kimura, Masashi Shimoda, Atsushi Obata, Junpei Sanada, Yoshiro Fushimi, Taka-aki Matsuoka & Kohei Kaku. (2022) Molecular Mechanism of Pancreatic β-Cell Failure in Type 2 Diabetes Mellitus. Biomedicines 10:4, pages 818.
Crossref
Jiani Liang, Margot Chirikjian, Utpal B. Pajvani & Alberto Bartolomé. (2022) MafA Regulation in β-Cells: From Transcriptional to Post-Translational Mechanisms. Biomolecules 12:4, pages 535.
Crossref
Rui Wu, Alexandros Karagiannopoulos, Lena Eliasson, Erik Renström, Cheng Luan & Enming Zhang. (2022) The Calcium Channel Subunit Gamma-4 as a Novel Regulator of MafA in Pancreatic Beta-Cell Controls Glucose Homeostasis. Biomedicines 10:4, pages 770.
Crossref
Luis Rodrigo Cataldo, Tania Singh, Kavya Achanta, Sara Bsharat, Rashmi B. Prasad, Cheng Luan, Erik Renström, Lena Eliasson & Isabella Artner. (2022) MAFA and MAFB regulate exocytosis‐related genes in human β‐cells. Acta Physiologica 234:2.
Crossref
Juan R. Alvarez-Dominguez & Douglas A. Melton. (2022) Cell maturation: Hallmarks, triggers, and manipulation. Cell 185:2, pages 235-249.
Crossref
Yi-Jung Hsu, Shih-Yen Wei, Teng-Yen Lin, Ling Fang, Yun-Ting Hsieh & Ying-Chieh Chen. (2022) A strategy to engineer vascularized tissue constructs by optimizing and maintaining the geometry. Acta Biomaterialia 138, pages 254-272.
Crossref
David W. Scoville & Anton M. Jetten. (2021) GLIS3: A Critical Transcription Factor in Islet β-Cell Generation. Cells 10:12, pages 3471.
Crossref
Yu Na Lee, Hye-Jin Yi, Eun Hye Seo, Jooyun Oh, Song Lee, Sarah Ferber, Teruo Okano, In Kyong Shim & Song Cheol Kim. (2021) Improvement of the therapeutic capacity of insulin-producing cells trans-differentiated from human liver cells using engineered cell sheet. Stem Cell Research & Therapy 12:1.
Crossref
Asghar Ghasemi. (2021) Uric acid‐induced pancreatic β-cell dysfunction. BMC Endocrine Disorders 21:1.
Crossref
Hirofumi Noguchi, Chika Miyagi-Shiohira, Takao Kinjo, Issei Saitoh & Masami Watanabe. (2021) In vivo evaluation of GG2–GG1/A2 element activity in the insulin promoter region using the CRISPR–Cas9 system. Scientific Reports 11:1.
Crossref
Shu-Yun Li, Xiaowei Gu, Anna Heinrich, Emily G Hurley, Blanche Capel & Tony DeFalco. (2021) Loss of Mafb and Maf distorts myeloid cell ratios and disrupts fetal mouse testis vascularization and organogenesis† . Biology of Reproduction 105:4, pages 958-975.
Crossref
Emily M. Walker, Jeeyeon Cha, Xin Tong, Min Guo, Jin-Hua Liu, Sophia Yu, Donato Iacovazzo, Franck Mauvais-Jarvis, Sarah E. Flanagan, Márta Korbonits, John Stafford, David A. Jacobson & Roland Stein. (2021) Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males. Cell Reports 37:2, pages 109813.
Crossref
Anthony S. Findley, Xinjun Zhang, Carly Boye, Yen Lung Lin, Cynthia A. Kalita, Luis Barreiro, Kirk E. Lohmueller, Roger Pique-Regi & Francesca Luca. (2021) A signature of Neanderthal introgression on molecular mechanisms of environmental responses. PLOS Genetics 17:9, pages e1009493.
Crossref
Ana Elena Rodriguez-Rodriguez, Esteban Porrini & Armando Torres. (2021) Beta-Cell Dysfunction Induced by Tacrolimus: A Way to Explain Type 2 Diabetes?. International Journal of Molecular Sciences 22:19, pages 10311.
Crossref
Hui Liu, Di Zhang, Yewen Zhou & Sheng Cui. (2021) MicroRNA-7a inhibits Isl1 expression to regulate insulin secretion by targeting Raf1 and Mapkap1 in NIT-1 cells. In Vitro Cellular & Developmental Biology - Animal 57:8, pages 817-824.
Crossref
Yichen Dai, Sonia Trigueros & Peter W. H. Holland. (2021) Compromised Function of the Pancreatic Transcription Factor PDX1 in a Lineage of Desert Rodents. Journal of Mammalian Evolution 28:3, pages 965-977.
Crossref
Luis Rodrigo Cataldo, Neelanjan Vishnu, Tania Singh, Ludivine Bertonnier-Brouty, Sara Bsharat, Cheng Luan, Erik Renström, Rashmi B. Prasad, Malin Fex, Hindrik Mulder & Isabella Artner. (2021) The MafA-target gene PPP1R1A regulates GLP1R-mediated amplification of glucose-stimulated insulin secretion in β-cells. Metabolism 118, pages 154734.
Crossref
Petra I. Lorenzo, Nadia Cobo-Vuilleumier, Eugenia Martín-Vázquez, Livia López-Noriega & Benoit R. Gauthier. (2021) Harnessing the Endogenous Plasticity of Pancreatic Islets: A Feasible Regenerative Medicine Therapy for Diabetes?. International Journal of Molecular Sciences 22:8, pages 4239.
Crossref
Xiaodong Zhu, Alexis Oguh, Morgan A. Gingerich, Scott A. Soleimanpour, Doris A. Stoffers & Maureen Gannon. (2021) Cell Cycle Regulation of the Pdx1 Transcription Factor in Developing Pancreas and Insulin-Producing β-Cells. Diabetes 70:4, pages 903-916.
Crossref
Min Zhu, Xiaohong Liu, Wen Liu, Yanrong Lu, Jingqiu Cheng & Younan Chen. (2021) β cell aging and age-related diabetes. Aging 13:5, pages 7691-7706.
Crossref
Emilie Blanchet, Laurence Pessemesse, Christine Feillet-Coudray, Charles Coudray, Chantal Cabello, Christelle Bertrand-Gaday & François Casas. (2021) p43, a Truncated Form of Thyroid Hormone Receptor α, Regulates Maturation of Pancreatic β Cells. International Journal of Molecular Sciences 22:5, pages 2489.
Crossref
Ji-Hyun Lee, Ji-Hyeon Lee & Sushil G Rane. (2021) TGF-β Signaling in Pancreatic Islet β Cell Development and Function. Endocrinology 162:3.
Crossref
J. Jason Collier, Heidi M. Batdorf, Thomas M. Martin, Kristen E. Rohli, David H. Burk, Danhong Lu, Chris R. Cooley, Michael D. Karlstad, Joseph W. Jackson, Tim E. Sparer, Jingying Zhang, Randall L. Mynatt & Susan J. Burke. (2021) Pancreatic, but not myeloid-cell, expression of interleukin-1alpha is required for maintenance of insulin secretion and whole body glucose homeostasis. Molecular Metabolism 44, pages 101140.
Crossref
Michela Novelli, Pascale Beffy, Matilde Masini, Chiara Vantaggiato, Luisa Martino, Lorella Marselli, Piero Marchetti & Vincenzo De Tata. (2021) Selective beta-cell toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin on isolated pancreatic islets. Chemosphere 265, pages 129103.
Crossref
Satoru Takahashi. (2021) Functional analysis of large MAF transcription factors and elucidation of their relationships with human diseases. Experimental Animals 70:3, pages 264-271.
Crossref
Ana Elena Rodríguez-Rodríguez, Esteban Porrini, Mads Hornum, Javier Donate-Correa, Raúl Morales-Febles, Simran Khemlani Ramchand, María Xixiang Molina Lima & Armando Torres. (2021) Post-Transplant Diabetes Mellitus and Prediabetes in Renal Transplant Recipients: An Update. Nephron 145:4, pages 317-329.
Crossref
Aharon Helman & Douglas A. Melton. (2021) A Stem Cell Approach to Cure Type 1 Diabetes. Cold Spring Harbor Perspectives in Biology 13:1, pages a035741.
Crossref
B.O.S. Camara, N.M. Ocarino, B.M. Bertassoli, C. Malm, F.R. Araújo, A.M.S. Reis, E.C. Jorge, E.G.L. Alves & R. Serakides. (2021) Differentiation of canine adipose mesenchymal stem cells into insulin-producing cells: comparison of different culture medium compositions. Domestic Animal Endocrinology 74, pages 106572.
Crossref
Bernhard Kleine & Winfried RossmanithBernhard Kleine & Winfried G. Rossmanith. 2021. Hormone und Hormonsystem - Lehrbuch der Endokrinologie. Hormone und Hormonsystem - Lehrbuch der Endokrinologie 397 560 .
Hideaki Kaneto, Atsushi Obata, Tomohiko Kimura, Masashi Shimoda, Junpei Sanada, Yoshiro Fushimi, Naoto Katakami, Takaaki Matsuoka & Kohei Kaku. (2020) Notable Underlying Mechanism for Pancreatic β-Cell Dysfunction and Atherosclerosis: Pleiotropic Roles of Incretin and Insulin Signaling. International Journal of Molecular Sciences 21:24, pages 9444.
Crossref
Jung Hun Oh, Allen Tannenbaum & Joseph O. Deasy. (2020) Identification of biological correlates associated with respiratory failure in COVID-19. BMC Medical Genomics 13:1.
Crossref
Ze Yan, Hetian Huang, Ellen Freebern, Daniel J. A. Santos, Dongmei Dai, Jingfang Si, Chong Ma, Jie Cao, Gang Guo, George E. Liu, Li Ma, Lingzhao Fang & Yi Zhang. (2020) Integrating RNA-Seq with GWAS reveals novel insights into the molecular mechanism underpinning ketosis in cattle. BMC Genomics 21:1.
Crossref
Vidul Goenka, Tanhai Borkar, Aska Desai & Raunak Kumar Das. (2020) Therapeutic potential of mesenchymal stem cells in treating both types of diabetes mellitus and associated diseases. Journal of Diabetes & Metabolic Disorders 19:2, pages 1979-1993.
Crossref
Xiankun Cao, Wenxin He, Yichuan Pang, Yu Cao & An Qin. (2020) Redox-dependent and independent effects of thioredoxin interacting protein. Biological Chemistry 401:11, pages 1215-1231.
Crossref
Yincheng Zhao, Hongyu Chen, Chunqing Li, Shanyuan Chen & Heng Xiao. (2020) Comparative Transcriptomics Reveals the Molecular Genetic Basis of Cave Adaptability in Sinocyclocheilus Fish Species. Frontiers in Ecology and Evolution 8.
Crossref
Bertrand Duvillié, Rayane Kourdoughli, Sabine Druillennec, Alain Eychène & Celio Pouponnot. (2020) Interplay Between Diabetes and Pancreatic Ductal Adenocarcinoma and Insulinoma: The Role of Aging, Genetic Factors, and Obesity. Frontiers in Endocrinology 11.
Crossref
Yanan Cao, Lin Li, Min Xu, Zhimin Feng, Xiaohui Sun, Jieli Lu, Yu Xu, Peina Du, Tiange Wang, Ruying Hu, Zhen Ye, Lixin Shi, Xulei Tang, Li Yan, Zhengnan Gao, Gang Chen, Yinfei Zhang, Lulu Chen, Guang Ning, Yufang Bi & Weiqing Wang. (2020) The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals. Cell Research 30:9, pages 717-731.
Crossref
Constantin Berger & Daniela Zdzieblo. (2020) Glucose transporters in pancreatic islets. Pflügers Archiv - European Journal of Physiology 472:9, pages 1249-1272.
Crossref
Hui Huang, Taylor N. Bader & Sha Jin. (2020) Signaling Molecules Regulating Pancreatic Endocrine Development from Pluripotent Stem Cell Differentiation. International Journal of Molecular Sciences 21:16, pages 5867.
Crossref
Zhaobin Deng, Yuka Matsumoto, Akihiro Kuno, Masami Ojima, Gulibaikelamu Xiafukaiti & Satoru Takahashi. (2020) An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout under MafA-Deficient Condition. International Journal of Molecular Sciences 21:16, pages 5606.
Crossref
Cathleen M. Courtney, Zeenat A. Shyr, Zihan Yan, Emily Jean Onufer, Allie E. Steinberger, Maria E. Tecos, Lauren K. Barron, Jun Guo, Maria S. Remedi & Brad W. Warner. (2020) Alterations in pancreatic islet cell function in response to small bowel resection. American Journal of Physiology-Gastrointestinal and Liver Physiology 319:1, pages G36-G42.
Crossref
Tijun Wu, Shuang Zhang, Jialiang Xu, Yaqin Zhang, Tong Sun, Yixue Shao, Jiahui Wang, Wei Tang, Fang Chen & Xiao Han. (2020) HRD1, an Important Player in Pancreatic β-Cell Failure and Therapeutic Target for Type 2 Diabetic Mice. Diabetes 69:5, pages 940-953.
Crossref
Aref G. Ebrahimi, Jennifer Hollister-Lock, Brooke A. Sullivan, Ryohei Tsuchida, Susan Bonner-Weir & Gordon C. Weir. (2020) Beta cell identity changes with mild hyperglycemia: Implications for function, growth, and vulnerability. Molecular Metabolism 35, pages 100959.
Crossref
Joan Camunas-Soler, Xiao-Qing Dai, Yan Hang, Austin Bautista, James Lyon, Kunimasa Suzuki, Seung K. Kim, Stephen R. Quake & Patrick E. MacDonald. (2020) Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes. Cell Metabolism 31:5, pages 1017-1031.e4.
Crossref
Aharon Helman, Andrew L. Cangelosi, Jeffrey C. Davis, Quan Pham, Arielle Rothman, Aubrey L. Faust, Juerg R. Straubhaar, David M. Sabatini & Douglas A. Melton. (2020) A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion. Cell Metabolism 31:5, pages 1004-1016.e5.
Crossref
Shuanshuan Xu, Dezhe Qin, Hong Yang, Chen He, Wenqing Liu, Na Tian, Yudong Wei, Xin He, Jinlian Hua & Sha Peng. (2020) SerpinB1 promotes the proliferation of porcine pancreatic stem cells through the STAT3 signaling pathway. The Journal of Steroid Biochemistry and Molecular Biology 198, pages 105537.
Crossref
Samuel Hamilton, Rafael de Cabo & Michel Bernier. (2020) Maternally expressed gene 3 in metabolic programming. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1863:4, pages 194396.
Crossref
Ke Zhu, Yumei Lai, Huiling Cao, Xiaochun Bai, Chuanju Liu, Qinnan Yan, Liting Ma, Di Chen, Giedrius Kanaporis, Junqi Wang, Luyuan Li, Tao Cheng, Yong Wang, Chuanyue Wu & Guozhi Xiao. (2020) Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice. Nature Communications 11:1.
Crossref
Shan Wan, Jie Zhang, Xiang Chen, Jiangli Lang, Li Li, Fei Chen, Li Tian, Yang Meng & Xijie Yu. (2020) MicroRNA-17-92 Regulates Beta-Cell Restoration After Streptozotocin Treatment. Frontiers in Endocrinology 11.
Crossref
Yu-Hsin Chang, Megumi C. Katoh, Ahmed M. Abdellatif, Guli Xiafukaiti, Abdelaziz Elzeftawy, Masami Ojima, Seiya Mizuno, Akihiro Kuno & Satoru Takahashi. (2020) Uncovering the role of MAFB in glucagon production and secretion in pancreatic α-cells using a new α-cell-specific <i>Mafb</i> conditional knockout mouse model. Experimental Animals 69:2, pages 178-188.
Crossref
Michito Hamada, Yuki Tsunakawa, Hyojung Jeon, Manoj Kumar Yadav & Satoru Takahashi. (2020) Role of MafB in macrophages. Experimental Animals 69:1, pages 1-10.
Crossref
Spencer R. Andrei & Maureen Gannon. 2020. Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas. Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas 171 182 .
Darshan Badal, Mahinder Paul, Neenu Jacob & Naresh Sachdeva. 2020. Advanced Concepts in Human Immunology: Prospects for Disease Control. Advanced Concepts in Human Immunology: Prospects for Disease Control 161 227 .
Tajudeen O. Yahaya & Titilola F. Salisu. (2019) A Review of Type 2 Diabetes Mellitus Predisposing Genes. Current Diabetes Reviews 16:1, pages 52-61.
Crossref
M. S Kaligin, A. A Titova, D. I Andreeva, M. A Titova, A. A Gumerova & A. P Kiyasov. (2019) IN EXPERIMENTAL RAT DIABETES TRANSCRIPTION FACTOR MAFA IS SYNTHESIZED IN DIFFERENTIATED PANCREATIC ISLET CELLS AND DOES NOT SERVE AS A MARKER OF PROGENITOR CELLS. Genes & Cells 14:3, pages 137-141.
Crossref
Jung-Hwa Han, Suji Kim, Suji Kim, Heejung Lee, So-Young Park & Chang-Hoon Woo. (2019) FMK, an Inhibitor of p90RSK, Inhibits High Glucose-Induced TXNIP Expression via Regulation of ChREBP in Pancreatic β Cells. International Journal of Molecular Sciences 20:18, pages 4424.
Crossref
Ashley A. Christensen & Maureen Gannon. (2019) The Beta Cell in Type 2 Diabetes. Current Diabetes Reports 19:9.
Crossref
Alexa K. Wade, Yanping Liu, Maigen M. Bethea, Eliana Toren, Hubert M. Tse & Chad S. Hunter. (2019) LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet β-cell function. Journal of Biological Chemistry 294:31, pages 11728-11740.
Crossref
Amanda Oakie, Zhi-Chao Feng, Jinming Li, Jenna Silverstein, Siu-Pok Yee & Rennian Wang. (2019) Long-term c-Kit overexpression in beta cells compromises their function in ageing mice. Diabetologia 62:8, pages 1430-1444.
Crossref
Tania Singh, Jesper K. Colberg, Luis Sarmiento, Patricia Chaves, Lisbeth Hansen, Sara Bsharat, Luis R. Cataldo, Monika Dudenhöffer-Pfeifer, Malin Fex, David Bryder, Dan Holmberg, Ewa Sitnicka, Corrado Cilio, Rashmi B. Prasad & Isabella Artner. (2019) Loss of MafA and MafB expression promotes islet inflammation. Scientific Reports 9:1.
Crossref
Mahmoud Hashemitabar & Elham Heidari. (2018) Redefining the signaling pathways from pluripotency to pancreas development: In vitro β‐cell differentiation. Journal of Cellular Physiology 234:6, pages 7811-7827.
Crossref
Alessia Mongelli, Fabio Martelli, Antonella Farsetti & Carlo Gaetano. (2019) The Dark That Matters: Long Non-coding RNAs as Master Regulators of Cellular Metabolism in Non-communicable Diseases. Frontiers in Physiology 10.
Crossref
Jackson Nteeba, Kaiyu Kubota, Wenfang Wang, Hao Zhu, Jay L Vivian, Guoli Dai & Michael J Soares. (2019) Pancreatic prolactin receptor signaling regulates maternal glucose homeostasis. Journal of Endocrinology 241:1, pages 71-83.
Crossref
Corinne Haller, Julie Piccand, Filippo De Franceschi, Yuki Ohi, Anindita Bhoumik, Christophe Boss, Umberto De Marchi, Guillaume Jacot, Sylviane Metairon, Patrick Descombes, Andreas Wiederkehr, Alessio Palini, Nicolas Bouche, Pascal Steiner, Olivia G. Kelly & Marine R.-C. Kraus. (2019) Macroencapsulated Human iPSC-Derived Pancreatic Progenitors Protect against STZ-Induced Hyperglycemia in Mice. Stem Cell Reports 12:4, pages 787-800.
Crossref
Maigen Bethea, Yanping Liu, Alexa K. Wade, Rachel Mullen, Rajesh Gupta, Vasily Gelfanov, Richard DiMarchi, Sushant Bhatnagar, Richard Behringer, Kirk M. Habegger & Chad S. Hunter. (2019) The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis. American Journal of Physiology-Endocrinology and Metabolism 316:3, pages E397-E409.
Crossref
Tania Singh, Luis Sarmiento, Cheng Luan, Rashmi B. Prasad, Jenny Johansson, Luis R. Cataldo, Erik Renström, Shamit Soneji, Corrado Cilio & Isabella Artner. (2018) MafA Expression Preserves Immune Homeostasis in Human and Mouse Islets. Genes 9:12, pages 644.
Crossref
Alberto Bartolome, Changyu Zhu, Lori Sussel & Utpal B. Pajvani. (2018) Notch signaling dynamically regulates adult β cell proliferation and maturity. Journal of Clinical Investigation 129:1, pages 268-280.
Crossref
Yanan Zhu, Yihui Li, Chengting Dai, Lu Sun, Lianghui You, Wei De, Qingxin Yuan, Ning Wang & Yuanyuan Chen. (2018) Inhibition of Lincpint expression affects insulin secretion and apoptosis in mouse pancreatic β cells. The International Journal of Biochemistry & Cell Biology 104, pages 171-179.
Crossref
Hiroki Matsuda. (2018) Zebrafish as a model for studying functional pancreatic β cells development and regeneration. Development, Growth & Differentiation 60:6, pages 393-399.
Crossref
Susan J. Burke, Heidi M. Batdorf, David H. Burk, Thomas M. Martin, Tamra Mendoza, Krisztian Stadler, Wateen Alami, Michael D. Karlstad, Matthew J. Robson, Randy D. Blakely, Randall L. Mynatt & J. Jason Collier. (2018) Pancreatic deletion of the interleukin-1 receptor disrupts whole body glucose homeostasis and promotes islet β-cell de-differentiation. Molecular Metabolism 14, pages 95-107.
Crossref
Nadiah GhazalliXiaoxing WuStephanie WalkerNancy TrieuLi-Yu HsinJustin ChoeChialin ChenJasper HsuJeanne LeBonMark T. KozlowskiJeffrey RawsonDavid A. TirrellM.L. Richard YipHsun Teresa Ku. (2018) Glucocorticoid Signaling Enhances Expression of Glucose-Sensing Molecules in Immature Pancreatic Beta-Like Cells Derived from Murine Embryonic Stem Cells In Vitro. Stem Cells and Development 27:13, pages 898-909.
Crossref
Liam J. Hawkins, Rasha Al-attar & Kenneth B. Storey. (2018) Transcriptional regulation of metabolism in disease: From transcription factors to epigenetics. PeerJ 6, pages e5062.
Crossref
Sirikul Kulanuwat, Prapaporn Jungtrakoon, Watip Tangjittipokin, Pa‑Thai Yenchitsomanus & Nattachet Plengvidhya. (2018) Fanconi anemia complementation group C protection against oxidative stress‑induced β‑cell apoptosis. Molecular Medicine Reports.
Crossref
Peter A. Kropp, Jennifer C. Dunn, Bethany A. Carboneau, Doris A. Stoffers & Maureen Gannon. (2018) Cooperative function of Pdx1 and Oc1 in multipotent pancreatic progenitors impacts postnatal islet maturation and adaptability. American Journal of Physiology-Endocrinology and Metabolism 314:4, pages E308-E321.
Crossref
Laura Villamayor, Elisa Rodríguez-Seguel, Raquel Araujo, Manuel Carrasco, Eva Bru-Tarí, José Manuel Mellado-Gil, Benoit R. Gauthier, Paola Martinelli, Iván Quesada, Bernat Soria, Franz Martín, David A. Cano & Anabel Rojas. (2018) GATA6 Controls Insulin Biosynthesis and Secretion in Adult β-Cells. Diabetes 67:3, pages 448-460.
Crossref
Ryo Iwaoka & Kohsuke Kataoka. (2018) Glucose regulates MafA transcription factor abundance and insulin gene expression by inhibiting AMP-activated protein kinase in pancreatic β-cells. Journal of Biological Chemistry 293:10, pages 3524-3534.
Crossref
Huijun Wang, Songshan Shi & Shunchun Wang. (2018) Can highly cited herbs in ancient Traditional Chinese medicine formulas and modern publications predict therapeutic targets for diabetes mellitus?. Journal of Ethnopharmacology 213, pages 101-110.
Crossref
Adrian Keong Kee Teo, Chang Siang Lim, Lih Feng Cheow, Tatsuya Kin, James A. Shapiro, Nam-Young Kang, William Burkholder & Hwee Hui Lau. (2018) Single-cell analyses of human islet cells reveal de-differentiation signatures. Cell Death Discovery 4:1.
Crossref
Mohammed Bensellam, Jean-Christophe Jonas & D Ross Laybutt. (2018) Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions. Journal of Endocrinology 236:2, pages R109-R143.
Crossref
Sara Al-Khawaga, Bushra Memon, Alexandra E. ButlerShahrad Taheri, Abdul B. Abou-Samra & Essam M. Abdelalim. (2018) Pathways governing development of stem cell-derived pancreatic β cells: lessons from embryogenesis. Biological Reviews 93:1, pages 364-389.
Crossref
Donato IacovazzoSarah E. FlanaganEmily WalkerRosana QuezadoFernando Antonio de Sousa BarrosRichard Caswell, Matthew B. JohnsonMatthew WakelingMichael BrändleMin GuoMary N. DangPlamena GabrovskaBruno NiederleEmanuel ChristStefan JenniBence SiposMaike NieserAndrea FrillingKetan DhatariyaPhilippe Chanson, Wouter W. de Herder, Björn Konukiewitz, Günter Klöppel, Roland SteinMárta KorbonitsSian Ellard. (2018) MAFA missense mutation causes familial insulinomatosis and diabetes mellitus . Proceedings of the National Academy of Sciences 115:5, pages 1027-1032.
Crossref
Adam Ramzy, Majid Mojibian & Timothy J Kieffer. (2018) Insulin-Deficient Mouse β -Cells Do Not Fully Mature but Can Be Remedied Through Insulin Replacement by Islet Transplantation . Endocrinology 159:1, pages 83-102.
Crossref
Yaxi Zhu, Qian Liu, Zhiguang Zhou & Yasuhiro Ikeda. (2017) PDX1, Neurogenin-3, and MAFA: critical transcription regulators for beta cell development and regeneration. Stem Cell Research & Therapy 8:1.
Crossref
Jason M. Spaeth, Manisha Gupte, Mark Perelis, Yu-Ping Yang, Holly Cyphert, Shuangli Guo, Jin-Hua Liu, Min Guo, Joseph Bass, Mark A. Magnuson, Christopher Wright & Roland Stein. (2017) Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning. Diabetes 66:11, pages 2830-2839.
Crossref
Aimée Bastidas-Ponce, Katharina Scheibner, Heiko Lickert & Mostafa Bakhti. (2017) Cellular and molecular mechanisms coordinating pancreas development. Development 144:16, pages 2873-2888.
Crossref
Junping Wen, Ting Xue, Ying Huang, Xiaoyan Chen, Ying Xue, Wei Lin, Lizhen Zhang, Jin Yao, Huibin Huang, Jixing Liang, Liantao Li, Lixiang Lin, Lidan Shi, Liangchun Cai, Zhuangli Zhu & Gang Chen. (2017) Is β-cell aging involved in the pathogenesis of diabetes?. Journal of Diabetes 9:7, pages 707-716.
Crossref
Jun Lu, Lingjing Lin, Huiyue Dong, Xin Meng, Fang Fang, Qinghua Wang, Lianghu Huang & Jianming Tan. (2017) Protein therapy using MafA fused to a polyarginine transduction domain attenuates glucose levels of streptozotocin-induced diabetic mice. Molecular Medicine Reports 15:6, pages 4041-4048.
Crossref
Hjalte List Larsen & Anne Grapin-Botton. (2017) The molecular and morphogenetic basis of pancreas organogenesis. Seminars in Cell & Developmental Biology 66, pages 51-68.
Crossref
Maxim Kaligin, Aleksandra Pliushkina, Angelina Titova, Marina Titova, Anisa Gumerova & Andrei Kiassov. (2016) Population Dynamics of MafA-Positive Cells During Ontogeny of Human Pancreas. BioNanoScience 7:2, pages 352-359.
Crossref
Taka-aki Matsuoka, Satoshi Kawashima, Takeshi Miyatsuka, Shugo Sasaki, Naoki Shimo, Naoto Katakami, Dan Kawamori, Satomi Takebe, Pedro L. Herrera, Hideaki Kaneto, Roland Stein & Iichiro Shimomura. (2017) Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells Into β-Cells In Vivo. Diabetes 66:5, pages 1293-1300.
Crossref
L. Shcherbina, A. Edlund, J.L.S. Esguerra, M. Abels, Y. Zhou, E. Ottosson-Laakso, C.B. Wollheim, O. Hansson, L. Eliasson & N. Wierup. (2017) Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes. Molecular and Cellular Endocrinology 447, pages 52-60.
Crossref
Kunio Hirano, Shuhei Konagaya, Alexander Turner, Yuichiro Noda, Shigeru Kitamura, Hidetoshi Kotera & Hiroo Iwata. (2017) Closed-channel culture system for efficient and reproducible differentiation of human pluripotent stem cells into islet cells. Biochemical and Biophysical Research Communications 487:2, pages 344-350.
Crossref
Tao Hao, Hongtao Zhang, Sheyu Li & Haoming Tian. (2017) Glucagon-like peptide 1 receptor agonist ameliorates the insulin resistance function of islet β cells via the activation of PDX-1/JAK signaling transduction in C57/BL6 mice with high-fat diet-induced diabetes. International Journal of Molecular Medicine 39:4, pages 1029-1036.
Crossref
Jennifer S.E. Liu & Matthias Hebrok. (2017) All mixed up: defining roles for β-cell subtypes in mature islets. Genes & Development 31:3, pages 228-240.
Crossref
Benjamin N. Ediger, Hee-Woong Lim, Christine Juliana, David N. Groff, LaQueena T. Williams, Giselle Dominguez, Jin-Hua Liu, Brandon L. Taylor, Erik R. Walp, Vasumathi Kameswaran, Juxiang Yang, Chengyang Liu, Chad S. Hunter, Klaus H. Kaestner, Ali Naji, Changhong Li, Maike Sander, Roland Stein, Lori Sussel, Kyoung-Jae Won, Catherine Lee May & Doris A. Stoffers. (2016) LIM domain–binding 1 maintains the terminally differentiated state of pancreatic β cells. Journal of Clinical Investigation 127:1, pages 215-229.
Crossref
Kristen E. SyringKayla A. BoortzJames K. OeserAlessandro UstioneKenneth A. Platt, Melanie K. Shadoan, Owen P. McGuinnessDavid W. PistonDavid R. Powell & Richard M. O’Brien. (2016) Combined Deletion of Slc30a7 and Slc30a8 Unmasks a Critical Role for ZnT8 in Glucose-Stimulated Insulin Secretion. Endocrinology 157:12, pages 4534-4541.
Crossref
Ting Yuan, Sahar Rafizadeh, Zahra Azizi, Blaz Lupse, Kanaka Durga Devi Gorrepati, Sushil Awal, Jose Oberholzer, Kathrin Maedler & Amin Ardestani. (2016) Proproliferative and antiapoptotic action of exogenously introduced YAP in pancreatic β cells. JCI Insight 1:18.
Crossref
Shumaila Usman, Irfan Khan, Nadia Naeem, Hana'a Iqbal, Anwar Ali, Sehrish Usman & Asmat Salim. (2016) Conditioned media trans-differentiate mature fibroblasts into pancreatic beta-like cells. Life Sciences 164, pages 52-59.
Crossref
Kiyoto Nishi, Yuichi Sato, Mikiko Ohno, Yoshinori Hiraoka, Sayaka Saijo, Jiro Sakamoto, Po-Min Chen, Yusuke Morita, Shintaro Matsuda, Kanako Iwasaki, Kazu Sugizaki, Norio Harada, Yoshiko Mukumoto, Hiroshi Kiyonari, Kenichiro Furuyama, Yoshiya Kawaguchi, Shinji Uemoto, Toru Kita, Nobuya Inagaki, Takeshi Kimura & Eiichiro Nishi. (2016) Nardilysin Is Required for Maintaining Pancreatic β-Cell Function. Diabetes 65:10, pages 3015-3027.
Crossref
Ling L. Chia, Ibrahim Jantan, Kien H. Chua, Kok W. Lam, Kamal Rullah & Mohd F. M. Aluwi. (2016) Effects of Tocotrienols on Insulin Secretion-Associated Genes Expression of Rat Pancreatic Islets in a Dynamic Culture. Frontiers in Pharmacology 7.
Crossref
Yanyan Zhao, Kun Shi, Xiaomei Su, Liqiang Xie & Yunjun Yan. (2016) Microcystin-LR induces dysfunction of insulin secretion in rat insulinoma (INS-1) cells: Implications for diabetes mellitus. Journal of Hazardous Materials 314, pages 11-21.
Crossref
Song-iee Han, Yukino Tsunekage & Kohsuke Kataoka. (2016) Phosphorylation of MafA enhances interaction with Beta2/NeuroD1. Acta Diabetologica 53:4, pages 651-660.
Crossref
Weiping Wang, Qiong Shi, Ting Guo, Zhe Yang, Zhuqing Jia, Ping Chen & Chunyan Zhou. (2016) PDX1 and ISL1 differentially coordinate with epigenetic modifications to regulate insulin gene expression in varied glucose concentrations. Molecular and Cellular Endocrinology 428, pages 38-48.
Crossref
Kathryn D. Henley, Diana E. Stanescu, Peter A. Kropp, Christopher V.E. Wright, Kyoung-Jae Won, Doris A. Stoffers & Maureen Gannon. (2016) Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function. Cell Reports 15:12, pages 2637-2650.
Crossref
Kenji Okita, Toru Mizuguchi, Ota Shigenori, Masayuki Ishii, Toshihiko Nishidate, Tomomi Ueki, Makoto Meguro, Yasutoshi Kimura, Naoki Tanimizu, Norihisa Ichinohe, Toshihiko Torigoe, Takashi Kojima, Toshihiro Mitaka, Noriyuki Sato, Norimasa Sawada & Koichi Hirata. (2015) Pancreatic regeneration: basic research and gene regulation. Surgery Today 46:6, pages 633-640.
Crossref
Elke Oetjen. (2016) Regulation of Beta-Cell Function and Mass by the Dual Leucine Zipper Kinase. Archiv der Pharmazie 349:6, pages 410-413.
Crossref
Leena Paul, Emily M. Walker, Yiannis Drosos, Holly A. Cyphert, Geoffrey Neale, Roland Stein, Jack South, Gerard Grosveld, Pedro L. Herrera & Beatriz Sosa-Pineda. (2016) Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells. Diabetes 65:3, pages 687-698.
Crossref
Hideaki Kaneto, Taka-aki Matsuoka, Tomohiko Kimura, Atsushi Obata, Masashi Shimoda, Shinji Kamei, Tomoatsu Mune & Kohei Kaku. (2016) Appropriate therapy for type 2 diabetes mellitus in view of pancreatic β-cell glucose toxicity: “the earlier, the better”. Journal of Diabetes 8:2, pages 183-189.
Crossref
Elvira Ganic, Tania Singh, Cheng Luan, João Fadista, Jenny K. Johansson, Holly Ann Cyphert, Hedvig Bennet, Petter Storm, Gaëlle Prost, Henrik Ahlenius, Erik Renström, Roland Stein, Leif Groop, Malin Fex & Isabella Artner. (2016) MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes. Cell Reports 14:8, pages 1991-2002.
Crossref
Ahmed M. Abdellatif, Hisashi Oishi, Takahiro Itagaki, Yunshin Jung, Hossam H. Shawki, Yukari Okita, Yoshikazu Hasegawa, Hiroyuki Suzuki, Salah E. El-Morsy, Mesbah A. El-Sayed, Mahmoud B. Shoaib, Fumihiro Sugiyama & Satoru Takahashi. (2016) β-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development. PLOS ONE 11:2, pages e0150010.
Crossref
Akihito Otsuki, Mikiko Suzuki, Fumiki Katsuoka, Kouhei Tsuchida, Hiromi Suda, Masanobu Morita, Ritsuko Shimizu & Masayuki Yamamoto. (2016) Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection. Free Radical Biology and Medicine 91, pages 45-57.
Crossref
Elizabeth ConradChunhua DaiJason SpaethMin GuoHolly A. CyphertDavid ScovilleJulie CarrollWei-Ming YuLisa V. GoodrichDavid M. HarlanKevin L. GroveCharles T. RobertsJr.Jr., Alvin C. Powers, Guoqiang Gu & Roland Stein. (2016) The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells. American Journal of Physiology-Endocrinology and Metabolism 310:1, pages E91-E102.
Crossref
Matthias Hebrok & Michael S. German. 2016. Endocrinology: Adult and Pediatric. Endocrinology: Adult and Pediatric 517 526.e5 .
Rosa Gasa, Ramon Gomis, Anna Novials & Joan-Marc Servitja. 2016. Molecular Nutrition and Diabetes. Molecular Nutrition and Diabetes 155 168 .
Vivian Anastasiou, Elpiniki Ninou, Dimitra Alexopoulou, Julia Stertmann, Andreas Müller, Andreas Dahl, Michele Solimena, Stephan Speier, Ioannis Serafimidis & Anthony Gavalas. (2015) Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice. Diabetologia 59:1, pages 139-150.
Crossref
Ananta Poudel, Omid Savari, Zehra Tekin & Manami Hara. 2016. Pancreatic Islet Biology. Pancreatic Islet Biology 49 63 .
Jennifer E. BruinAlireza RezaniaTimothy J. Kieffer. (2015) Replacing and safeguarding pancreatic β cells for diabetes. Science Translational Medicine 7:316.
Crossref
Jennifer E. Bruin, Ali Asadi, Jessica K. Fox, Suheda Erener, Alireza Rezania & Timothy J. Kieffer. (2015) Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice. Stem Cell Reports 5:6, pages 1081-1096.
Crossref
Ilham El Khattabi & Arun Sharma. (2015) Proper activation of MafA is required for optimal differentiation and maturation of pancreatic β-cells. Best Practice & Research Clinical Endocrinology & Metabolism 29:6, pages 821-831.
Crossref
Elvira Ganic, Jenny K. Johansson, Hedvig Bennet, Malin Fex & Isabella Artner. (2015) Islet-specific monoamine oxidase A and B expression depends on MafA transcriptional activity and is compromised in type 2 diabetes. Biochemical and Biophysical Research Communications 468:4, pages 629-635.
Crossref
Hiroshi Nomoto, Takuma Kondo, Hideaki Miyoshi, Akinobu Nakamura, Yoko Hida, Ken-ichiro Yamashita, Arun J. Sharma & Tatsuya Atsumi. (2015) Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion. Endocrinology 156:10, pages 3570-3580.
Crossref
Fang Chen, Jia Liu, Yanyang Wang, Tijun Wu, Wei Shan, Yunxia Zhu & Xiao Han. (2015) Aldosterone induces clonal β-cell failure through glucocorticoid receptor. Scientific Reports 5:1.
Crossref
Anthony I. Romer & Lori Sussel. (2015) Pancreatic islet cell development and regeneration. Current Opinion in Endocrinology, Diabetes & Obesity 22:4, pages 255-264.
Crossref
Junia C. Santos-Silva, Rosane Aparecida Ribeiro, Jean F. Vettorazzi, Esperanza Irles, Sarah Rickli, Patrícia C. Borck, Patricia M. Porciuncula, Ivan Quesada, Angel Nadal, Antonio C. Boschero & Everardo M. Carneiro. (2015) Taurine supplementation ameliorates glucose homeostasis, prevents insulin and glucagon hypersecretion, and controls β, α, and δ-cell masses in genetic obese mice. Amino Acids 47:8, pages 1533-1548.
Crossref
Aliashraf Godini, Asghar Ghasemi & Saleh Zahediasl. (2015) The Possible Mechanisms of the Impaired Insulin Secretion in Hypothyroid Rats. PLOS ONE 10:7, pages e0131198.
Crossref
Chun Yao, Hongqin Zhuang, Wei Cheng, Yan Lin, Pan Du, Bingya Yang, Xiaofeng Huang, Sheng Chen, Qingang Hu & Zi-Chun Hua. (2015) FADD phosphorylation impaired islet morphology and function. Journal of Cellular Physiology 230:7, pages 1448-1456.
Crossref
Huijun Wang, Songshan Shi, Bin Bao, Xiaojun Li & Shunchun Wang. (2015) Structure characterization of an arabinogalactan from green tea and its anti-diabetic effect. Carbohydrate Polymers 124, pages 98-108.
Crossref
Susan J. Burke, Amanda L. May, Robert C. Noland, Danhong Lu, Marcela Brissova, Alvin C. Powers, Elizabeth M. Sherrill, Michael D. Karlstad, Shawn R. Campagna, Jacqueline M. Stephens & J. Jason Collier. (2015) Thiobenzothiazole-modified Hydrocortisones Display Anti-inflammatory Activity with Reduced Impact on Islet β-Cell Function. Journal of Biological Chemistry 290:21, pages 13401-13416.
Crossref
Vincent Poitout, Roland Stein & Christopher J. Rhodes. 2015. International Textbook of Diabetes Mellitus. International Textbook of Diabetes Mellitus 82 95 .
Teresa L. Mastracci, Raghavendra G. Mirmira & Ryan M. Anderson. 2015. International Textbook of Diabetes Mellitus. International Textbook of Diabetes Mellitus 53 68 .
Talitha van der Meulen & Mark O Huising. (2015) Role of transcription factors in the transdifferentiation of pancreatic islet cells. Journal of Molecular Endocrinology 54:2, pages R103-R117.
Crossref
Hideaki Kaneto & Taka-aki Matsuoka. (2015) Role of Pancreatic Transcription Factors in Maintenance of Mature β-Cell Function. International Journal of Molecular Sciences 16:12, pages 6281-6297.
Crossref
Taka-aki Matsuoka, Hideaki Kaneto, Satoshi Kawashima, Takeshi Miyatsuka, Yoshihiro Tochino, Atsushi Yoshikawa, Akihisa Imagawa, Jun-ichi Miyazaki, Maureen Gannon, Roland Stein & Iichiro Shimomura. (2015) Preserving Mafa Expression in Diabetic Islet β-Cells Improves Glycemic Control in Vivo. Journal of Biological Chemistry 290:12, pages 7647-7657.
Crossref
Wataru Nishimura, Satoru Takahashi & Kazuki Yasuda. (2014) MafA is critical for maintenance of the mature beta cell phenotype in mice. Diabetologia 58:3, pages 566-574.
Crossref
Ahmed M. ABDELLATIF, Kiyohito OGATA, Takashi KUDO, Gulibaikelamu XIAFUKAITI, Yu-Hsin CHANG, Megumi C. KATOH, Salah E. EL-MORSY, Hisashi OISHI & Satoru TAKAHASHI. (2015) Role of large MAF transcription factors in the mouse endocrine pancreas. Experimental Animals 64:3, pages 305-312.
Crossref
Kimberly G. Riley & Maureen Gannon. 2015. Principles of Developmental Genetics. Principles of Developmental Genetics 565 590 .
Blair K. Gage, Rhonda D. Wideman & Timothy J. Kieffer. 2015. Islets of Langerhans. Islets of Langerhans 1335 1373 .
Manuel Carrasco, Anabel Rojas, Irene Delgado, Nadia Cobo Vuilleumier, Juan R. Tejedo, Francisco J. Bedoya, Benoit R. Gauthier, Bernat Soria & Franz Martín. 2015. Islets of Langerhans. Islets of Langerhans 109 128 .
Caitlin M. Braitsch & Ondine Cleaver. 2015. Tissue-Specific Stem Cell Niche. Tissue-Specific Stem Cell Niche 99 133 .
Bipasha Bose, Kishore Reddy Katikireddy & Sudheer Shenoy P. 2015. Obesity and Diabetes. Obesity and Diabetes 231 255 .
Jordan M. Thompson & Anna Di Gregorio. (2015) Insulin-like genes in ascidians: Findings in C iona and hypotheses on the evolutionary origins of the pancreas . genesis 53:1, pages 82-104.
Crossref
Yoshifumi Sato, Masahiro Inoue, Tatsuya Yoshizawa & Kazuya Yamagata. (2014) Moderate Hypoxia Induces β-Cell Dysfunction with HIF-1–Independent Gene Expression Changes. PLoS ONE 9:12, pages e114868.
Crossref
Benjamin N. Ediger, Aiping Du, Jingxuan Liu, Chad S. Hunter, Erik R. Walp, Jonathan Schug, Klaus H. Kaestner, Roland Stein, Doris A. Stoffers & Catherine L. May. (2014) Islet-1 Is Essential for Pancreatic β-Cell Function. Diabetes 63:12, pages 4206-4217.
Crossref
Julie Piccand, Perrine Strasser, David J. Hodson, Aline Meunier, Tao Ye, Céline Keime, Marie-Christine Birling, Guy A. Rutter & Gérard Gradwohl. (2014) Rfx6 Maintains the Functional Identity of Adult Pancreatic β Cells. Cell Reports 9:6, pages 2219-2232.
Crossref
Alireza Rezania, Jennifer E Bruin, Payal Arora, Allison Rubin, Irina Batushansky, Ali Asadi, Shannon O'Dwyer, Nina Quiskamp, Majid Mojibian, Tobias Albrecht, Yu Hsuan Carol Yang, James D Johnson & Timothy J Kieffer. (2014) Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nature Biotechnology 32:11, pages 1121-1133.
Crossref
Manpreet Kaur, Onkar Bedi, Shilpi Sachdeva, B. V. K. Krishna Reddy & Puneet Kumar. (2014) Rodent animal models: from mild to advanced stages of diabetic nephropathy. Inflammopharmacology 22:5, pages 279-293.
Crossref
Marie-Jeannette Stahnke, Corinna Dickel, Sabine Schröder, Diana Kaiser, Roland Blume, Roland Stein, Celio Pouponnot & Elke Oetjen. (2014) Inhibition of human insulin gene transcription and MafA transcriptional activity by the dual leucine zipper kinase. Cellular Signalling 26:9, pages 1792-1799.
Crossref
Koki Eto, Wataru Nishimura, Hisashi Oishi, Haruhide Udagawa, Miho Kawaguchi, Masaki Hiramoto, Toshiyoshi Fujiwara, Satoru Takahashi & Kazuki Yasuda. (2014) MafA Is Required for Postnatal Proliferation of Pancreatic β-Cells. PLoS ONE 9:8, pages e104184.
Crossref
Yan Hang, Tsunehiko Yamamoto, Richard K.P. Benninger, Marcela Brissova, Min Guo, Will Bush, David W. Piston, Alvin C. Powers, Mark Magnuson, Debbie C. Thurmond & Roland Stein. (2014) The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth. Diabetes 63:6, pages 1994-2005.
Crossref
Shiying Shao, Mingbo Nie, Cai Chen, Xi Chen, Muxun Zhang, Gang Yuan, Xuefeng Yu & Yan Yang. (2014) Protective Action of Liraglutide in Beta Cells Under Lipotoxic Stress Via PI3K/Akt/FoxO1 Pathway. Journal of Cellular Biochemistry 115:6, pages 1166-1175.
Crossref
Jacqueline V. Schiesser & James M. Wells. (2014) Generation of β cells from human pluripotent stem cells: Are we there yet?. Annals of the New York Academy of Sciences 1311:1, pages 124-137.
Crossref
Tao Zhang, Chiachen Chen, Mary B. Breslin, Kejing Song & Michael S. Lan. (2014) Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction. Cellular Signalling 26:4, pages 740-747.
Crossref
Hiroki Takeuchi, Norio Nakatsuji & Hirofumi Suemori. (2014) Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture. Scientific Reports 4:1.
Crossref
Tao Gao, Brian McKenna, Changhong Li, Maximilian Reichert, James Nguyen, Tarjinder Singh, Chenghua Yang, Archana Pannikar, Nicolai Doliba, Tingting Zhang, Doris A. Stoffers, Helena Edlund, Franz Matschinsky, Roland Stein & Ben Z. Stanger. (2014) Pdx1 Maintains β Cell Identity and Function by Repressing an α Cell Program. Cell Metabolism 19:2, pages 259-271.
Crossref
Michito Hamada, Megumi Nakamura, Mai Thi Nhu Tran, Takashi Moriguchi, Cynthia Hong, Takayuki Ohsumi, Tra Thi Huong Dinh, Manabu Kusakabe, Motochika Hattori, Tokio Katsumata, Satoko Arai, Katsuhiko Nakashima, Takashi Kudo, Etsushi Kuroda, Chien-Hui Wu, Pei-Han Kao, Masaharu Sakai, Hitoshi Shimano, Toru Miyazaki, Peter Tontonoz & Satoru Takahashi. (2014) MafB promotes atherosclerosis by inhibiting foam-cell apoptosis. Nature Communications 5:1.
Crossref
John F Mulley, Adam D Hargreaves, Matthew J Hegarty, R Heller & Martin T Swain. (2014) Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate pancreas function. BMC Genomics 15:1, pages 1074.
Crossref
Haizhao Luo, Rongping Chen, Rui Yang, Yan Liu, Youping Chen, Yi Shu & Hong Chen. (2014) Reprogramming of Mice Primary Hepatocytes into Insulin-Producing Cells by Transfection with Multicistronic Vectors. Journal of Diabetes Research 2014, pages 1-7.
Crossref
KaiHui Hu He, Kirstine Juhl, Michael Karadimos, Ilham El Khattabi, Connor Fitzpatrick, Susan Bonner-Weir & Arun Sharma. (2014) Differentiation of pancreatic endocrine progenitors reversibly blocked by premature induction of MafA. Developmental Biology 385:1, pages 2-12.
Crossref
Bipasha Bose, Kishore Reddy Katikireddy & Sudheer Shenoy P. 2014. The Pancreatic Beta Cell. The Pancreatic Beta Cell 223 248 .
Giacomo Lanzoni, Camillo Ricordi, Luca Inverardi & Juan Domínguez-Bendala. 2014. Regenerative Medicine Applications in Organ Transplantation. Regenerative Medicine Applications in Organ Transplantation 609 625 .
K.D. Henley & M. Gannon. 2014. Pathobiology of Human Disease. Pathobiology of Human Disease 2216 2228 .
Blair K. Gage, Rhonda D. Wideman & Timothy J. Kieffer. 2013. Islets of Langerhans, 2. ed.. Islets of Langerhans, 2. ed. 1 37 .
Franz Martín, Anabel Rojas, Manuel Carrasco, Irene Delgado, Nadia Cobo Vuilleumier, Juan R. Tejedo, Francisco. J. Bedoya, Dr. Benoit R. Gauthier & Bernat Soria. 2013. Islets of Langerhans, 2. ed.. Islets of Langerhans, 2. ed. 1 19 .
Blair K. Gage, Travis D. Webber & Timothy J. Kieffer. (2013) Initial Cell Seeding Density Influences Pancreatic Endocrine Development During in vitro Differentiation of Human Embryonic Stem Cells. PLoS ONE 8:12, pages e82076.
Crossref

Displaying 200 of 336 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.