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Jiaomeng Pan, Mao Zhang, Liangqing Dong, Shuyi Ji, Juan Zhang, Shu Zhang, Youpei Lin, Xiaoying Wang, Zhenbin Ding, Shuangjian Qiu, Daming Gao, Jian Zhou, Jia Fan & Qiang Gao. (2023) Genome-Scale CRISPR screen identifies LAPTM5 driving lenvatinib resistance in hepatocellular carcinoma. Autophagy 19:4, pages 1184-1198.
Read now
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Fan Zhang, Siti Mariam Zakaria, Vedrana Högqvist Tabor, Madhurendra Singh, Susanna Tronnersjö, Jacob Goodwin, Galina Selivanova, Jiri Bartek, Alina Castell & Lars-Gunnar Larsson. (2018) MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts. Cell Cycle 17:24, pages 2697-2715.
Read now
Read now
K. Pham, A. Kan, L. Whitehead, R. J. Hennessy, K. Rogers & P. D. Hodgkin. (2018) Converse Smith-Martin cell cycle kinetics by transformed B lymphocytes. Cell Cycle 17:16, pages 2041-2051.
Read now
Read now
Tinke L. Vormer, Floris Foijer, Camiel L. C. Wielders & Hein te Riele. (2008) Anchorage-Independent Growth of Pocket Protein-Deficient Murine Fibroblasts Requires Bypass of G2 Arrest and Can Be Accomplished by Expression of TBX2. Molecular and Cellular Biology 28:24, pages 7263-7273.
Read now
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Poppy P. Fotiadou, Chiaki Takahashi, Hasan N. Rajabi & Mark E. Ewen. (2007) Wild-Type NRas and KRas Perform Distinct Functions during Transformation. Molecular and Cellular Biology 27:19, pages 6742-6755.
Read now
Read now
Xiaowei Zhang, Jiyoung Kim, Robin Ruthazer, Michael A. McDevitt, David E. Wazer, K. Eric Paulson & Amy S. Yee. (2006) The HBP1 Transcriptional Repressor Participates in RAS-Induced Premature Senescence. Molecular and Cellular Biology 26:22, pages 8252-8266.
Read now
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Articles from other publishers (123)
Tianzhuo Wang, Huiying Guo, Lei Zhang, Miao Yu, Qianchen Li, Jing Zhang, Yan Tang, Hongquan Zhang & Jun Zhan. (2023) FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression. Frontiers of Medicine.
Crossref
Crossref
Ricardo Iván Martínez-Zamudio, Alketa Stefa, José Américo Nabuco Leva Ferreira Freitas, Themistoklis Vasilopoulos, Mark Simpson, Gregory Doré, Pierre-François Roux, Mark A. Galan, Ravi J. Chokshi, Oliver Bischof & Utz Herbig. (2023) Escape from oncogene-induced senescence is controlled by POU2F2 and memorized by chromatin scars. Cell Genomics 3:4, pages 100293.
Crossref
Crossref
Terrance J. HaanenIIIIII, Caitlin M. O'Connor & Goutham Narla. (2022) Biased holoenzyme assembly of protein phosphatase 2A (PP2A): From cancer to small molecules. Journal of Biological Chemistry 298:12, pages 102656.
Crossref
Crossref
Tianzhuo Wang, Huiying Guo, Qianchen Li, Weijie Wu, Miao Yu, Lei Zhang, Cuicui Li, Jiagui Song, Zhenbin Wang, Jing Zhang, Yan Tang, Lei Kang, Hongquan Zhang & Jun Zhan. (2022) The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations. Cell Reports 40:8, pages 111210.
Crossref
Crossref
Masahiro Shimizu, Hiroshi Shibuya & Nobuyuki Tanaka. (2022) Enhanced O-GlcNAc modification induced by the RAS/MAPK/CDK1 pathway is required for SOX2 protein expression and generation of cancer stem cells. Scientific Reports 12:1.
Crossref
Crossref
Xiangpeng Dai, Xiaoling Zhang, Qing Yin, Jia Hu, Jianping Guo, Yang Gao, Aidan H. Snell, Hiroyuki Inuzuka, Lixin Wan & Wenyi Wei. (2022) Acetylation-dependent regulation of BRAF oncogenic function. Cell Reports 38:3, pages 110250.
Crossref
Crossref
Liangqing Dong, Dayun Lu, Ran Chen, Youpei Lin, Hongwen Zhu, Zhou Zhang, Shangli Cai, Peng Cui, Guohe Song, Dongning Rao, Xinpei Yi, Yingcheng Wu, Nixue Song, Fen Liu, Yunhao Zou, Shu Zhang, Xiaoming Zhang, Xiaoying Wang, Shuangjian Qiu, Jian Zhou, Shisheng Wang, Xu Zhang, Yongyong Shi, Daniel Figeys, Li Ding, Pei Wang, Bing Zhang, Henry Rodriguez, Qiang Gao, Daming Gao, Hu Zhou & Jia Fan. (2022) Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma. Cancer Cell 40:1, pages 70-87.e15.
Crossref
Crossref
Qiwei Jiang, Nana Zheng, Lang Bu, Xiaomei Zhang, Xiaoling Zhang, Yuanzhong Wu, Yaqing Su, Lei Wang, Xiaomin Zhang, Shancheng Ren, Xiangpeng Dai, Depei Wu, Wei Xie, Wenyi Wei, Yasheng Zhu & Jianping Guo. (2021) SPOP-mediated ubiquitination and degradation of PDK1 suppresses AKT kinase activity and oncogenic functions. Molecular Cancer 20:1.
Crossref
Crossref
Lynette M Phillips, Shoudong Li, Joy Gumin, Marc Daou, Daniel Ledbetter, Jing Yang, Sanjay Singh, Brittany C Parker Kerrigan, Anwar Hossain, Ying Yuan, Candelaria Gomez-Manzano, Juan Fueyo & Frederick F Lang. (2021) An immune-competent, replication-permissive Syrian Hamster glioma model for evaluating Delta-24-RGD oncolytic adenovirus. Neuro-Oncology 23:11, pages 1911-1921.
Crossref
Crossref
Udit Parekh, Daniella McDonald, Amir Dailamy, Yan Wu, Thekla Cordes, Kun Zhang, Ann Tipps, Christian Metallo & Prashant Mali. (2021) Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas. iScience 24:10, pages 103149.
Crossref
Crossref
Biswajyoti Sahu, Päivi Pihlajamaa, Kaiyang Zhang, Kimmo Palin, Saija Ahonen, Alejandra Cervera, Ari Ristimäki, Lauri A. Aaltonen, Sampsa Hautaniemi & Jussi Taipale. (2021) Human cell transformation by combined lineage conversion and oncogene expression. Oncogene 40:36, pages 5533-5547.
Crossref
Crossref
Duygu Kuzuoglu-Ozturk, Zhiqiang Hu, Martina Rama, Emily Devericks, Jacob Weiss, Gary G. Chiang, Stephen T. Worland, Steven E. Brenner, Hani Goodarzi, Luke A. Gilbert & Davide Ruggero. (2021) Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome. Cell Reports 35:13, pages 109321.
Crossref
Crossref
Ziran Zhao, Holly Fowle, Henkel Valentine, Zemin Liu, Yinfei Tan, Jianming Pei, Simone Badal, Joseph R. Testa & Xavier Graña. (2020) Immortalization of human primary prostate epithelial cells via CRISPR inactivation of the CDKN2A locus and expression of telomerase. Prostate Cancer and Prostatic Diseases 24:1, pages 233-243.
Crossref
Crossref
Çağrı Öner & Ertuğrul Çolak. (2021) PIWI Interacting RNA-651 Inhibition Transforms the Genetic Features of MCF-7 Breast Cancer Cells. Oncologie 23:3, pages 393-407.
Crossref
Crossref
Jing Liu, Yunhua Peng, Le Shi, Lixin Wan, Hiroyuki Inuzuka, Jiangang Long, Jianping Guo, Jinfang Zhang, Min Yuan, Shuangxi Zhang, Xun Wang, Jing Gao, Xiangpeng Dai, Shozo Furumoto, Lijun Jia, Pier Paolo Pandolfi, John M. Asara, William G. KaelinJr.Jr., Jiankang Liu & Wenyi Wei. (2020) Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle. Cell Research 31:1, pages 80-93.
Crossref
Crossref
Jonathan M Geisinger & Tim Stearns. (2020) CRISPR/Cas9 treatment causes extended TP53-dependent cell cycle arrest in human cells. Nucleic Acids Research 48:16, pages 9067-9081.
Crossref
Crossref
Parastoo Shahrouzi, Ianire Astobiza, Ana R. Cortazar, Verónica Torrano, Alice Macchia, Juana M. Flores, Chiara Niespolo, Isabel Mendizabal, Ruben Caloto, Amaia Ercilla, Laura Camacho, Leire Arreal, Maider Bizkarguenaga, Maria L. Martinez-Chantar, Xose R. Bustelo, Edurne Berra, Endre Kiss-Toth, Guillermo Velasco, Amaia Zabala-Letona & Arkaitz Carracedo. (2020) Genomic and Functional Regulation of TRIB1 Contributes to Prostate Cancer Pathogenesis. Cancers 12:9, pages 2593.
Crossref
Crossref
Mitsuo Sato, Jerry W. Shay & John D. Minna. (2020) Immortalized normal human lung epithelial cell models for studying lung cancer biology. Respiratory Investigation 58:5, pages 344-354.
Crossref
Crossref
Giacomo Canesin, Annalisa Di Ruscio, Mailin Li, Simone Ummarino, Andreas Hedblom, Reeham Choudhury, Agnieszka Krzyzanowska, Eva Csizmadia, Macarena Palominos, Anna Stiehm, Alexander Ebralidze, Shao-Yong Chen, Mahmoud A. Bassal, Ping Zhao, Emanuela Tolosano, Laurence Hurley, Anders Bjartell, Daniel G. Tenen & Barbara Wegiel. (2020) Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases. Cell Reports 32:12, pages 108181.
Crossref
Crossref
Maria Grzes, Magdalena Oron, Zuzanna Staszczak, Akanksha Jaiswar, Magdalena Nowak-Niezgoda & Dawid Walerych. (2020) A Driver Never Works Alone—Interplay Networks of Mutant p53, MYC, RAS, and Other Universal Oncogenic Drivers in Human Cancer. Cancers 12:6, pages 1532.
Crossref
Crossref
Jia Liu, Qinyu Yao, Lei Xiao, Wen Ma, Fan Li, Baochang Lai & Nanping Wang. (2019)
PPAR
γ induces
NEDD
4 gene expression to promote autophagy and insulin action
. The FEBS Journal 287:3, pages 529-545.
Crossref
Crossref
Wenjian Gan, Xiaoming Dai, Xiangpeng Dai, Jun Xie, Shasha Yin, Junjie Zhu, Chen Wang, Yuchen Liu, Jianping Guo, Min Wang, Jing Liu, Jia Hu, Ryan J. Quinton, Neil J. Ganem, Pengda Liu, John M. Asara, Pier Paolo Pandolfi, Yingzi Yang, Zhigang He, Guangping Gao & Wenyi Wei. (2020) LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nature Cell Biology 22:2, pages 246-256.
Crossref
Crossref
Jong Wook Kim, Christian Berrios, Miju Kim, Amy E Schade, Guillaume Adelmant, Huwate Yeerna, Emily Damato, Amanda Balboni Iniguez, Laurence Florens, Michael P Washburn, Kim Stegmaier, Nathanael S Gray, Pablo Tamayo, Ole Gjoerup, Jarrod A Marto, James DeCaprio & William C Hahn. (2020) STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells. eLife 9.
Crossref
Crossref
Ralitsa R. Madsen & Bart Vanhaesebroeck. (2020) Cracking the context-specific PI3K signaling code. Science Signaling 13:613.
Crossref
Crossref
Maliheh Khademi-Shirvan, Mahsa Ghorbaninejad, Samaneh Hosseini & Mohamadreza Baghaban Eslaminejad. 2020. Cell Biology and Translational Medicine, Volume 9. Cell Biology and Translational Medicine, Volume 9
87
102
.
Eros Di Giorgio, Harikrishnareddy Paluvai, Raffaella Picco & Claudio Brancolini. (2019) Genetic Programs Driving Oncogenic Transformation: Lessons from In Vitro Models. International Journal of Molecular Sciences 20:24, pages 6283.
Crossref
Crossref
Shigekazu Murakami, Ivan Nemazanyy, Shannon M. White, Hengye Chen, Chan D.K. Nguyen, Garrett T. Graham, Dieter Saur, Mario Pende & Chunling Yi. (2019) A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas. Developmental Cell 51:1, pages 113-128.e9.
Crossref
Crossref
Qiang Gao, Hongwen Zhu, Liangqing Dong, Weiwei Shi, Ran Chen, Zhijian Song, Chen Huang, Junqiang Li, Xiaowei Dong, Yanting Zhou, Qian Liu, Lijie Ma, Xiaoying Wang, Jian Zhou, Yansheng Liu, Emily Boja, Ana I. Robles, Weiping Ma, Pei Wang, Yize Li, Li Ding, Bo Wen, Bing Zhang, Henry Rodriguez, Daming Gao, Hu Zhou & Jia Fan. (2019) Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma. Cell 179:2, pages 561-577.e22.
Crossref
Crossref
Tao Han, Shulong Jiang, Hong Zheng, Qing Yin, Mengyu Xie, Margaret R Little, Xiu Yin, Ming Chen, Su Jung Song, Amer A. Beg, Pier Paolo Pandolfi & Lixin Wan. (2019) Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. Nature Communications 10:1.
Crossref
Crossref
Qing Yin, Tao Han, Bin Fang, Guolin Zhang, Chao Zhang, Evan R. Roberts, Victoria Izumi, Mengmeng Zheng, Shulong Jiang, Xiu Yin, Minjung Kim, Jianfeng Cai, Eric B. Haura, John M. Koomen, Keiran S. M. Smalley & Lixin Wan. (2019) K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling. Nature Communications 10:1.
Crossref
Crossref
Miodrag Dragoj, Jasna Bankovic, Ana Podolski-Renic, Sonja Stojkovic Buric, Milica Pesic, Nikola Tanic & Tijana Stankovic. (2019) Association of overexpressed MYC gene with altered PHACTR3 and E2F4 genes contributes to non-small cell lung carcinoma pathogenesis. Journal of Medical Biochemistry 38:2, pages 188-195.
Crossref
Crossref
Shujing Liu, Gao Zhang, Jianping Guo, Xiang Chen, Jingce Lei, Kan Ze, Liyun Dong, Xiangpeng Dai, Yang Gao, Daisheng Song, Brett L. Ecker, Ruifeng Yang, Caitlin Feltcher, Kai Peng, Cheng Feng, Hui Chen, Rebecca X. Lee, Heddy Kerestes, Jingwen Niu, Suresh Kumar, Weiting Xu, Jie Zhang, Zhi Wei, James S. Martin, Xiaoming Liu, Gordon Mills, Yiling Lu, Wei Guo, Lunquan Sun, Lin Zhang, Ashani Weeraratna, Meenhard Herlyn, Wenyi Wei, Frank S. Lee & Xiaowei Xu. (2018) Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis. Nature Communications 9:1.
Crossref
Crossref
Harikrishnareddy Paluvai, Eros Di Giorgio & Claudio Brancolini. (2018)
Unscheduled
HDAC
4 repressive activity in human fibroblasts triggers
TP
53‐dependent senescence and favors cell transformation
. Molecular Oncology 12:12, pages 2165-2181.
Crossref
Crossref
Xiaoduo Xie, Hongli Hu, Xinyuan Tong, Long Li, Xiangyuan Liu, Min Chen, Huairui Yuan, Xia Xie, Qingrun Li, Yuxue Zhang, Huafang Ouyang, Mengqi Wei, Jing Huang, Pengda Liu, Wenjian Gan, Yong Liu, Anyong Xie, Xiaoling Kuai, Gung-Wei Chirn, Hu Zhou, Rong Zeng, Ronggui Hu, Jun Qin, Fei-Long Meng, Wenyi Wei, Hongbin Ji & Daming Gao. (2018) The mTOR–S6K pathway links growth signalling to DNA damage response by targeting RNF168. Nature Cell Biology 20:3, pages 320-331.
Crossref
Crossref
Lixin Wan, Kexin Xu, Yongkun Wei, Jinfang Zhang, Tao Han, Christopher Fry, Zhao Zhang, Yao Vickie Wang, Liyu Huang, Min Yuan, Weiya Xia, Wei-Chao Chang, Wen-Chien Huang, Chien-Liang Liu, Yuan-Ching Chang, Jinsong Liu, Yun Wu, Victor X. Jin, Xiangpeng Dai, Jianfeng Guo, Jia Liu, Shulong Jiang, Jin Li, John M. Asara, Myles Brown, Mien-Chie Hung & Wenyi Wei. (2018) Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Molecular Cell 69:2, pages 279-291.e5.
Crossref
Crossref
Susan J. Gelman, Fuad Naser, Nathaniel G. Mahieu, Lisa D. McKenzie, Gavin P. Dunn, Milan G. Chheda & Gary J. Patti. (2018) Consumption of NADPH for 2-HG Synthesis Increases Pentose Phosphate Pathway Flux and Sensitizes Cells to Oxidative Stress. Cell Reports 22:2, pages 512-522.
Crossref
Crossref
Zhe Yang, John Maciejowski & Titia de Lange. (2017) Nuclear Envelope Rupture Is Enhanced by Loss of p53 or Rb. Molecular Cancer Research 15:11, pages 1579-1586.
Crossref
Crossref
Marika Mannerström, Tarja Toimela, Jertta-Riina Sarkanen & Tuula Heinonen. (2017)
Human BJ Fibroblasts is an Alternative to Mouse BALB/c 3T3 Cells in
In Vitro
Neutral Red Uptake Assay
. Basic & Clinical Pharmacology & Toxicology 121, pages 109-115.
Crossref
Crossref
Xiangpeng Dai, Wenjian Gan, Xiaoning Li, Shangqian Wang, Wei Zhang, Ling Huang, Shengwu Liu, Qing Zhong, Jianping Guo, Jinfang Zhang, Ting Chen, Kouhei Shimizu, Francisco Beca, Mirjam Blattner, Divya Vasudevan, Dennis L Buckley, Jun Qi, Lorenz Buser, Pengda Liu, Hiroyuki Inuzuka, Andrew H Beck, Liewei Wang, Peter J Wild, Levi A Garraway, Mark A Rubin, Christopher E Barbieri, Kwok-Kin Wong, Senthil K Muthuswamy, Jiaoti Huang, Yu Chen, James E Bradner & Wenyi Wei. (2017) Prostate cancer–associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nature Medicine 23:9, pages 1063-1071.
Crossref
Crossref
Arman Javadi, Ravi K Deevi, Emma Evergren, Elodie Blondel-Tepaz, George S Baillie, Mark GH Scott & Frederick C Campbell. (2017) PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex. eLife 6.
Crossref
Crossref
Lixin Wan, Ming Chen, Juxiang Cao, Xiangpeng Dai, Qing Yin, Jinfang Zhang, Su-Jung Song, Ying Lu, Jing Liu, Hiroyuki Inuzuka, Jesse M. Katon, Kelsey Berry, Jacqueline Fung, Christopher Ng, Pengda Liu, Min Sup Song, Lian Xue, Roderick T. Bronson, Marc W. Kirschner, Rutao Cui, Pier Paolo Pandolfi & Wenyi Wei. (2017) The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function. Cancer Discovery 7:4, pages 424-441.
Crossref
Crossref
Mert Ozturk, Yinghui Li & Vinay Tergaonkar. (2017) Current Insights to Regulation and Role of Telomerase in Human Diseases. Antioxidants 6:1, pages 17.
Crossref
Crossref
Dana Hamam, Mohamed Abdouh, Zu-Hua Gao, Vincenzo Arena, Manuel Arena & Goffredo Orazio Arena. (2016) Transfer of malignant trait to BRCA1 deficient human fibroblasts following exposure to serum of cancer patients. Journal of Experimental & Clinical Cancer Research 35:1.
Crossref
Crossref
Fang Li, Xinjian Liu, John H. Sampson, Darell D. Bigner & Chuan-Yuan Li. (2016) Rapid Reprogramming of Primary Human Astrocytes into Potent Tumor-Initiating Cells with Defined Genetic Factors. Cancer Research 76:17, pages 5143-5150.
Crossref
Crossref
Yunhua Peng, Jing Liu, Le Shi, Ying Tang, Dan Gao, Jiangang Long & Jiankang Liu. (2016) Mitochondrial dysfunction precedes depression of AMPK/AKT signaling in insulin resistance induced by high glucose in primary cortical neurons. Journal of Neurochemistry 137:5, pages 701-713.
Crossref
Crossref
Rui Shao, Jia Liu, Guang Yan, Jinfang Zhang, Yujiao Han, Jianfeng Guo, Zhan Xu, Zhu Yuan, Jiankang Liu, Marcos Malumbres, Lixin Wan, Wenyi Wei & Weiguo Zou. (2016) Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid. Cell Research 26:6, pages 699-712.
Crossref
Crossref
Laurent Jacqueroud, Charlotte Bouard, Geoffrey Richard, Léa Payen, Mojgan Devouassoux-Shisheboran, Douglas B. Spicer, Julie Caramel, Guillaume Collin, Alain Puisieux, Agnès Tissier & Stéphane Ansieau. (2016) The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells. Neoplasia 18:5, pages 317-327.
Crossref
Crossref
Philippe Rousseau, Shanjadia Khondaker, Shusen Zhu, Catherine Lauzon, Sabine Mai & Chantal Autexier. (2016) An intact putative mouse telomerase essential N-terminal domain is necessary for proper telomere maintenance. Biology of the Cell 108:4, pages 96-112.
Crossref
Crossref
A Saalfrank, K-P Janssen, M Ravon, K Flisikowski, S Eser, K Steiger, T Flisikowska, P Müller-Fliedner, É Schulze, C Brönner, A Gnann, E Kappe, B Böhm, B Schade, U Certa, D Saur, I Esposito, A Kind & A Schnieke. (2016) A porcine model of osteosarcoma. Oncogenesis 5:3, pages e210-e210.
Crossref
Crossref
Jia Liu, Lixin Wan, Jing Liu, Zhu Yuan, Jinfang Zhang, Jianfeng Guo, Marcos Malumbres, Jiankang Liu, Weiguo Zou & Wenyi Wei. (2016) Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner. Cell Discovery 2:1.
Crossref
Crossref
Nitesh Sharma, Vera Magistroni, Rocco Piazza, Stefania Citterio, Caterina Mezzatesta, Praveen Khandelwal, Alessandra Pirola & Carlo Gambacorti-Passerini. (2015) BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene. Molecular Cancer 14:1.
Crossref
Crossref
Juxiang CaoXiangpeng DaiLixin WanHongshen WangJinfang ZhangPhilip S. GoffElena V. SviderskayaZhenyu XuanZhixiang XuXiaowei XuPhilip HindsKeith T. FlahertyDouglas V. FallerColin R. GodingYongjun WangWenyi WeiRutao Cui. (2015)
The E3 ligase APC/C
Cdh1
promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth
. Science Signaling 8:392.
Crossref
Crossref
Wilhelm Engström, Philippa Darbre, Staffan Eriksson, Linda Gulliver, Tove Hultman, Michalis V. Karamouzis, James E. Klaunig, Rekha Mehta, Kim Moorwood, Thomas Sanderson, Hideko Sone, Pankaj Vadgama, Gerard Wagemaker, Andrew Ward, Neetu Singh, Fahd Al-Mulla, Rabeah Al-Temaimi, Amedeo Amedei, Anna Maria Colacci, Monica Vaccari, Chiara Mondello, A.Ivana Scovassi, Jayadev Raju, Roslida A. Hamid, Lorenzo Memeo, Stefano Forte, Rabindra Roy, Jordan Woodrick, Hosni K. Salem, Elizabeth Ryan, Dustin G. Brown & William H. Bisson. (2015) The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling. Carcinogenesis 36:Suppl 1, pages S38-S60.
Crossref
Crossref
Masao Takeuchi, Atsunori Higashino, Kikuko Takeuchi, Yutaro Hori, Kazuko Koshiba-Takeuchi, Hatsune Makino, Yoko Monobe, Marina Kishida, Jun Adachi, Jun Takeuchi, Takeshi Tomonaga, Akihiro Umezawa, Yosuke Kameoka & Ken-ichi Akagi. (2015) Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation. PLOS ONE 10:5, pages e0126562.
Crossref
Crossref
Erica Salvati, Angela Rizzo, Sara Iachettini, Pasquale Zizza, Chiara Cingolani, Carmen D'Angelo, Manuela Porru, Chiara Mondello, Aurora Aiello, Antonella Farsetti, Eric Gilson, Carlo Leonetti & Annamaria Biroccio. (2015) A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds. Nucleic Acids Research 43:3, pages 1759-1769.
Crossref
Crossref
. 2015. Systems Biology of Cancer. Systems Biology of Cancer
169
322
.
. 2015. Systems Biology of Cancer. Systems Biology of Cancer
93
168
.
L. E. Becker, A. A. L. Takwi, Z. Lu & Y. Li. (2014) The role of miR-200a in mammalian epithelial cell transformation. Carcinogenesis 36:1, pages 2-12.
Crossref
Crossref
Mohamed Abdouh, Shufeng Zhou, Vincenzo Arena, Manuel Arena, Anthoula Lazaris, Ronald Onerheim, Peter Metrakos & Goffredo Orazio Arena. (2014) Transfer of malignant trait to immortalized human cells following exposure to human cancer serum. Journal of Experimental & Clinical Cancer Research 33:1.
Crossref
Crossref
NINGJING LEI, BO PENG & JIAN-YING ZHANG. (2014) CIP2A regulates cell proliferation via the AKT signaling pathway in human lung cancer. Oncology Reports 32:4, pages 1683-1694.
Crossref
Crossref
Eyal Ben-David, Assaf C. Bester, Sagiv Shifman & Batsheva Kerem. (2014) Transcriptional Dynamics in Colorectal Carcinogenesis: New Insights into the Role of c-Myc and miR17 in Benign to Cancer Transformation. Cancer Research 74:19, pages 5532-5540.
Crossref
Crossref
Sam D Molyneux, Paul D Waterhouse, Dawne Shelton, Yang W Shao, Christopher M Watling, Qing-Lian Tang, Isaac S Harris, Brendan C Dickson, Pirashaanthy Tharmapalan, Geir K Sandve, Xiaoyang Zhang, Swneke D Bailey, Hal Berman, Jay S Wunder, Zsuzsanna Izsvák, Mathieu Lupien, Tak W Mak & Rama Khokha. (2014) Human somatic cell mutagenesis creates genetically tractable sarcomas. Nature Genetics 46:9, pages 964-972.
Crossref
Crossref
Pavan Kumar P, Uchenna Emechebe, Richard Smith, Sarah Franklin, Barry Moore, Mark Yandell, Stephen L Lessnick & Anne M Moon. (2014) Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. eLife 3.
Crossref
Crossref
Hongmei Yang, Xuanyu Chen, Xuegang Wang, Yansheng Li, Shaoyong Chen, Xiaohui Qian, Rong Wang, Li Chen, Weiwei Han, Anming Ruan, Quansheng Du, Aria F. Olumi & Xiaoping Zhang. (2014) Inhibition of PP2A Activity Confers a TRAIL-Sensitive Phenotype during Malignant Transformation. Molecular Cancer Research 12:2, pages 217-227.
Crossref
Crossref
Xiaosong Huang, Siddharth Shah, Jing Wang, Zhaohui Ye, Sarah N Dowey, Kit Man Tsang, Laurel G Mendelsohn, Gregory J Kato, Thomas S Kickler & Linzhao Cheng. (2014) Extensive Ex Vivo Expansion of Functional Human Erythroid Precursors Established From Umbilical Cord Blood Cells by Defined Factors. Molecular Therapy 22:2, pages 451-463.
Crossref
Crossref
Ishaan C. Jagan, Ravi K. Deevi, Aliya Fatehullah, Rebecca Topley, Joshua Eves, Michael Stevenson, Maurice Loughrey, Kenneth Arthur & Frederick Charles Campbell. (2013) PTEN Phosphatase-Independent Maintenance of Glandular Morphology in a Predictive Colorectal Cancer Model System. Neoplasia 15:11, pages 1218-1230.
Crossref
Crossref
Pengda Liu, Wenjian Gan, Hiroyuki Inuzuka, Adam S. Lazorchak, Daming Gao, Omotooke Arojo, Dou Liu, Lixin Wan, Bo Zhai, Yonghao Yu, Min Yuan, Byeong Mo Kim, Shavali Shaik, Suchithra Menon, Steven P. Gygi, Tae Ho Lee, John M. Asara, Brendan D. Manning, John Blenis, Bing Su & Wenyi Wei. (2013) Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis. Nature Cell Biology 15:11, pages 1340-1350.
Crossref
Crossref
Hidefumi Fukushima, Kohei Ogura, Lixin Wan, Ying Lu, Victor Li, Daming Gao, Pengda Liu, Alan W. Lau, Tao Wu, Marc W. Kirschner, Hiroyuki Inuzuka & Wenyi Wei. (2013) SCF-Mediated Cdh1 Degradation Defines a Negative Feedback System that Coordinates Cell-Cycle Progression. Cell Reports 4:4, pages 803-816.
Crossref
Crossref
Riccardo Di Fiore, Antonella D'Anneo, Giovanni Tesoriere & Renza Vento. (2013) RB1 in cancer: Different mechanisms of RB1 inactivation and alterations of pRb pathway in tumorigenesis. Journal of Cellular Physiology 228:8, pages 1676-1687.
Crossref
Crossref
Alan W Lau, Hiroyuki Inuzuka, Hidefumi Fukushima, Lixin Wan, Pengda Liu, Daming Gao, Yi Sun & Wenyi Wei. (2013) Regulation of APCCdh1 E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7. Cell Research 23:7, pages 947-961.
Crossref
Crossref
Mitsuo Sato, Jill E. Larsen, Woochang Lee, Han Sun, David S. Shames, Maithili P. Dalvi, Ruben D. Ramirez, Hao Tang, John Michael DiMaio, Boning Gao, Yang Xie, Ignacio I. Wistuba, Adi F. Gazdar, Jerry W. Shay & John D. Minna. (2013) Human Lung Epithelial Cells Progressed to Malignancy through Specific Oncogenic Manipulations. Molecular Cancer Research 11:6, pages 638-650.
Crossref
Crossref
Ulrike Ulbricht, Anette Sommer, Georg Beckmann, Manuel Lutzenberger, Henrik Seidel, Bertolt Kreft & Luisella Toschi. (2013) Isogenic human mammary epithelial cell lines: novel tools for target identification and validation. Breast Cancer Research and Treatment 138:2, pages 437-456.
Crossref
Crossref
I Jagan, A Fatehullah, R K Deevi, V Bingham & F C Campbell. (2012) Rescue of glandular dysmorphogenesis in PTEN-deficient colorectal cancer epithelium by PPARγ-targeted therapy. Oncogene 32:10, pages 1305-1315.
Crossref
Crossref
S Thaler, M Schmidt, A Schad & J P Sleeman. (2012) RASSF1A inhibits estrogen receptor alpha expression and estrogen-independent signalling: implications for breast cancer development. Oncogene 31:47, pages 4912-4922.
Crossref
Crossref
Kirti Magudia, Aurelia Lahoz & Alan Hall. (2012) K-Ras and B-Raf oncogenes inhibit colon epithelial polarity establishment through up-regulation of c-myc. Journal of Cell Biology 198:2, pages 185-194.
Crossref
Crossref
Y Shrestha, E J Schafer, J S Boehm, S R Thomas, F He, J Du, S Wang, J Barretina, B A Weir, J J Zhao, K Polyak, T R Golub, R Beroukhim & W C Hahn. (2011) PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling. Oncogene 31:29, pages 3397-3408.
Crossref
Crossref
Hiroyuki Inuzuka, Daming Gao, Lydia W.S. Finley, Wen Yang, Lixin Wan, Hidefumi Fukushima, Y. Rebecca Chin, Bo Zhai, Shavali Shaik, Alan W. Lau, Zhiwei Wang, Steven P. Gygi, Keiko Nakayama, Julie Teruya-Feldstein, Alex Toker, Marcia C. Haigis, Pier Paolo Pandolfi & Wenyi Wei. (2012) Acetylation-Dependent Regulation of Skp2 Function. Cell 150:1, pages 179-193.
Crossref
Crossref
Maryline Herbet, Aude Salomon, Jean-Jacques Feige & Michaël Thomas. (2012) Acquisition Order of Ras and p53 Gene Alterations Defines Distinct Adrenocortical Tumor Phenotypes. PLoS Genetics 8:5, pages e1002700.
Crossref
Crossref
Naoko OkamotoMami YasukawaChristine NguyenVivi KasimYoshiko MaidaRichard PossematoTatsuhiro Shibata, Keith L. LigonKiyoko FukamiWilliam C. Hahn & Kenkichi Masutomi. (2011) Maintenance of tumor initiating cells of defined genetic composition by nucleostemin. Proceedings of the National Academy of Sciences 108:51, pages 20388-20393.
Crossref
Crossref
Hiu Wing Cheung, Jinyan Du, Jesse S. Boehm, Frank He, Barbara A. Weir, Xiaoxing Wang, Mohit Butaney, Lecia V. Sequist, Biao Luo, Jeffrey A. Engelman, David E. Root, Matthew Meyerson, Todd R. Golub, Pasi A. Jänne & William C. Hahn. (2011)
Amplification of
CRKL
Induces Transformation and Epidermal Growth Factor Receptor Inhibitor Resistance in Human Non–Small Cell Lung Cancers
. Cancer Discovery 1:7, pages 608-625.
Crossref
Crossref
Lixin Wan, Weiguo Zou, Daming Gao, Hiroyuki Inuzuka, Hidefumi Fukushima, Anders H. Berg, Rebecca Drapp, Shavali Shaik, Dorothy Hu, Chantel Lester, Manuel Eguren, Marcos Malumbres, Laurie H. Glimcher & Wenyi Wei. (2011) Cdh1 Regulates Osteoblast Function through an APC/C-Independent Modulation of Smurf1. Molecular Cell 44:5, pages 721-733.
Crossref
Crossref
R Deevi, A Fatehullah, I Jagan, M Nagaraju, V Bingham & F C Campbell. (2011) PTEN regulates colorectal epithelial apoptosis through Cdc42 signalling. British Journal of Cancer 105:9, pages 1313-1321.
Crossref
Crossref
Daming Gao, Hiroyuki Inuzuka, Meng-Kwang Marcus Tan, Hidefumi Fukushima, Jason W. Locasale, Pengda Liu, Lixin Wan, Bo Zhai, Y. Rebecca Chin, Shavali Shaik, Costas A. Lyssiotis, Steven P. Gygi, Alex Toker, Lewis C. Cantley, John M. Asara, J. Wade Harper & Wenyi Wei. (2011) mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTOR. Molecular Cell 44:2, pages 290-303.
Crossref
Crossref
Byeong-Moo Kim, Janghee Woo, Chryssa Kanellopoulou & Ramesh A. Shivdasani. (2011) Regulation of mouse stomach development and Barx1 expression by specific microRNAs. Development 138:6, pages 1081-1086.
Crossref
Crossref
Mark M. Pomerantz, Yashaswi Shrestha, Richard J. Flavin, Meredith M. Regan, Kathryn L. Penney, Lorelei A. Mucci, Meir J. Stampfer, David J. Hunter, Stephen J. Chanock, Eric J. Schafer, Jennifer A. Chan, Josep Tabernero, José Baselga, Andrea L. Richardson, Massimo Loda, William K. Oh, Philip W. Kantoff, William C. Hahn & Matthew L. Freedman. (2010) Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis. PLoS Genetics 6:11, pages e1001204.
Crossref
Crossref
Daming Gao, Lixin Wan, Hiroyuki Inuzuka, Anders H. Berg, Alan Tseng, Bo Zhai, Shavali Shaik, Eric Bennett, Adriana E. Tron, Jessica A. Gasser, Alan Lau, Steven P. Gygi, J. Wade Harper, James A. DeCaprio, Alex Toker & Wenyi Wei. (2010) Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction. Molecular Cell 39:5, pages 797-808.
Crossref
Crossref
Wolfgang WagnerAnthony D. HoMartin Zenke. (2010) Different Facets of Aging in Human Mesenchymal Stem Cells. Tissue Engineering Part B: Reviews 16:4, pages 445-453.
Crossref
Crossref
Claire JosseRenaud SchoemansNeville-Andrew NiessenMarie DelgaudineAnne-Cécile HellinChristian HerensPhilippe DelvenneVincent Bours. (2010) Systematic Chromosomal Aberrations Found in Murine Bone Marrow-Derived Mesenchymal Stem Cells. Stem Cells and Development 19:8, pages 1167-1173.
Crossref
Crossref
Hiroyuki Inuzuka, Alan Tseng, Daming Gao, Bo Zhai, Qing Zhang, Shavali Shaik, Lixin Wan, Xiaolu L. Ang, Caroline Mock, Haoqiang Yin, Jayne M. Stommel, Steven Gygi, Galit Lahav, John Asara, Zhi-Xiong Jim Xiao, William G. KaelinJr.Jr., J. Wade Harper & Wenyi Wei. (2010) Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase. Cancer Cell 18:2, pages 147-159.
Crossref
Crossref
Johans Fakhoury, Delphine Tamara Marie-Egyptienne, José-Arturo Londoño-Vallejo & Chantal Autexier. (2010) Telomeric function of mammalian telomerases at short telomeres. Journal of Cell Science 123:10, pages 1693-1704.
Crossref
Crossref
Weinong Han, Mei Ming, Tong-Chuan He & Yu-Ying He. (2010) Immunosuppressive Cyclosporin A Activates AKT in Keratinocytes through PTEN Suppression. Journal of Biological Chemistry 285:15, pages 11369-11377.
Crossref
Crossref
Ami Albihn, John Inge Johnsen & Marie Arsenian Henriksson. 2010.
163
224
.
Elena Sotillo & Xavier Graña. 2010. Cell Cycle Deregulation in Cancer. Cell Cycle Deregulation in Cancer
3
22
.
Qing Zhang, Jinming Gu, Lianjie Li, Jiayun Liu, Biao Luo, Hiu-Wing Cheung, Jesse S. Boehm, Min Ni, Christoph Geisen, David E. Root, Kornelia Polyak, Myles Brown, Andrea L. Richardson, William C. Hahn, William G. KaelinJr.Jr. & Archana Bommi-Reddy. (2009) Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase. Cancer Cell 16:5, pages 413-424.
Crossref
Crossref
Bala S. Balakumaran, Alessandro Porrello, David S. Hsu, Wayne Glover, Adam Foye, Janet Y. Leung, Beth A. Sullivan, William C. Hahn, Massimo Loda & Phillip G. Febbo. (2009) MYC Activity Mitigates Response to Rapamycin in Prostate Cancer through Eukaryotic Initiation Factor 4E–Binding Protein 1–Mediated Inhibition of Autophagy. Cancer Research 69:19, pages 7803-7810.
Crossref
Crossref
Jingwei Cheng, James A. DeCaprio, Michele M. Fluck & Brian S. Schaffhausen. (2009) Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens. Seminars in Cancer Biology 19:4, pages 218-228.
Crossref
Crossref
Daming GaoHiroyuki InuzukaMichael Korenjak, Alan TsengTao Wu, Lixin WanMarc Kirschner, Nicholas Dyson & Wenyi Wei. (2009) Cdh1 Regulates Cell Cycle through Modulating the Claspin/Chk1 and the Rb/E2F1 Pathways. Molecular Biology of the Cell 20:14, pages 3305-3316.
Crossref
Crossref
Angela C. Hirbe, Anke J. Roelofs, Desiree H. Floyd, Hongju Deng, Stephanie N. Becker, Lisa G. Lanigan, Anthony J. Apicelli, Zhiqiang Xu, Julie L. Prior, Mark C. Eagleton, David Piwnica-Worms, Michael J. Rogers & Katherine Weilbaecher. (2009) The bisphosphonate zoledronic acid decreases tumor growth in bone in mice with defective osteoclasts. Bone 44:5, pages 908-916.
Crossref
Crossref
Delphine T. Marie-Egyptienne, Marie Eve Brault, Graeme A.M. Nimmo, J. Arturo Londoño-Vallejo & Chantal Autexier. (2009) Growth defects in mouse telomerase RNA-deficient cells expressing a template-mutated mouse telomerase RNA. Cancer Letters 275:2, pages 266-276.
Crossref
Crossref
Ian F. Dunn & William C. Hahn. 2009. Oncology of Infancy and Childhood. Oncology of Infancy and Childhood
41
55
.
D Zhuang, S Mannava, V Grachtchouk, W-H Tang, S Patil, J A Wawrzyniak, A E Berman, T J Giordano, E V Prochownik, M S Soengas & M A Nikiforov. (2008) C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells. Oncogene 27:52, pages 6623-6634.
Crossref
Crossref
K Araki, K Kawauchi & N Tanaka. (2008) IKK/NF-κB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors. Oncogene 27:43, pages 5696-5705.
Crossref
Crossref
Ricardo D. Coletta, Kimberly L. Christensen, Douglas S. Micalizzi, Paul Jedlicka, Marileila Varella-Garcia & Heide L. Ford. (2008) Six1 Overexpression in Mammary Cells Induces Genomic Instability and Is Sufficient for Malignant Transformation. Cancer Research 68:7, pages 2204-2213.
Crossref
Crossref
Jukka Westermarck & William C. Hahn. (2008) Multiple pathways regulated by the tumor suppressor PP2A in transformation. Trends in Molecular Medicine 14:4, pages 152-160.
Crossref
Crossref
Alka M. Mahale, Zahid A.T. Khan, Makoto Igarashi, Gouri J. Nanjangud, Rui Fang Qiao, Shen Yao, Sam W. Lee & Stuart A. Aaronson. (2008) Clonal Selection in Malignant Transformation of Human Fibroblasts Transduced with Defined Cellular Oncogenes. Cancer Research 68:5, pages 1417-1426.
Crossref
Crossref
Na-Kyung Yoo, Chul-Woong Pyo, Youngho Kim, Byung-Yoon Ahn & Sang-Yun Choi. (2008) Vaccinia virus-mediated cell cycle alteration involves inactivation of tumour suppressors associated with Brf1 and TBP. Cellular Microbiology 10:3, pages 583-592.
Crossref
Crossref
Mona L. Gauthier, Hal K. Berman, Caroline Miller, Krystyna Kozakeiwicz, Karen Chew, Dan Moore, Joseph Rabban, Yunn Yi Chen, Karla Kerlikowske & Thea D. Tlsty. (2007) Abrogated Response to Cellular Stress Identifies DCIS Associated with Subsequent Tumor Events and Defines Basal-like Breast Tumors. Cancer Cell 12:5, pages 479-491.
Crossref
Crossref
Hiroyuki Konishi, Bedri Karakas, Abde M. Abukhdeir, Josh Lauring, John P. Gustin, Joseph P. Garay, Yuko Konishi, Eike Gallmeier, Kurtis E. Bachman & Ben Ho Park. (2007)
Knock-in of Mutant K-
ras
in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-
ras
–Mediated Transformation
. Cancer Research 67:18, pages 8460-8467.
Crossref
Crossref
Paolo Neviani, Ramasamy Santhanam, Joshua J. Oaks, Anna M. Eiring, Mario Notari, Bradley W. Blaser, Shujun Liu, Rossana Trotta, Natarajan Muthusamy, Carlo Gambacorti-Passerini, Brian J. Druker, Jorge Cortes, Guido Marcucci, Ching-Shih Chen, Nicole M. Verrills, Denis C. Roy, Michael A. Caligiuri, Clara D. Bloomfield, John C. Byrd & Danilo Perrotti. (2007) FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia. Journal of Clinical Investigation 117:9, pages 2408-2421.
Crossref
Crossref
Mekala Gunaratnam, Olga Greciano, Cristina Martins, Anthony P. Reszka, Christoph M. Schultes, Hamid Morjani, Jean-Francois Riou & Stephen Neidle. (2007) Mechanism of acridine-based telomerase inhibition and telomere shortening. Biochemical Pharmacology 74:5, pages 679-689.
Crossref
Crossref
Jiahuai Han & Peiqing Sun. (2007) The pathways to tumor suppression via route p38. Trends in Biochemical Sciences 32:8, pages 364-371.
Crossref
Crossref
Jing Jiao, Shunyou Wang, Rong Qiao, Igor Vivanco, Philip A. Watson, Charles L. Sawyers & Hong Wu. (2007)
Murine Cell Lines Derived from
Pten
Null Prostate Cancer Show the Critical Role of PTEN in Hormone Refractory Prostate Cancer Development
. Cancer Research 67:13, pages 6083-6091.
Crossref
Crossref
Aubrey D.N.J. de Grey. (2007) Protagonistic pleiotropy: Why cancer may be the only pathogenic effect of accumulating nuclear mutations and epimutations in aging. Mechanisms of Ageing and Development 128:7-8, pages 456-459.
Crossref
Crossref
Jesse S. Boehm, Jean J. Zhao, Jun Yao, So Young Kim, Ron Firestein, Ian F. Dunn, Sarah K. Sjostrom, Levi A. Garraway, Stanislawa Weremowicz, Andrea L. Richardson, Heidi Greulich, Carly J. Stewart, Laura A. Mulvey, Rhine R. Shen, Lauren Ambrogio, Tomoko Hirozane-Kishikawa, David E. Hill, Marc Vidal, Matthew Meyerson, Jennifer K. Grenier, Greg Hinkle, David E. Root, Thomas M. Roberts, Eric S. Lander, Kornelia Polyak & William C. Hahn. (2007) Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene. Cell 129:6, pages 1065-1079.
Crossref
Crossref
Anna A. Sablina, Wen Chen, Jason D. Arroyo, Laura Corral, Melissa Hector, Sara E. Bulmer, James A. DeCaprio & William C. Hahn. (2007) The Tumor Suppressor PP2A Aβ Regulates the RalA GTPase. Cell 129:5, pages 969-982.
Crossref
Crossref
Cristina Martins, Mekala Gunaratnam, John Stuart, Vaidahi Makwana, Olga Greciano, Anthony P. Reszka, Lloyd R. Kelland & Stephen Neidle. (2007) Structure-based design of benzylamino-acridine compounds as G-quadruplex DNA telomere targeting agents. Bioorganic & Medicinal Chemistry Letters 17:8, pages 2293-2298.
Crossref
Crossref
Kristi L. Berger, Felicia Barriga, Michael J. Lace, Lubomir P. Turek, Gideon J. Zamba, Frederick E. Domann, John H. Lee & Aloysius J. Klingelhutz. (2006) Cervical keratinocytes containing stably replicating extrachromosomal HPV-16 are refractory to transformation by oncogenic H-Ras. Virology 356:1-2, pages 68-78.
Crossref
Crossref
Seok-Geun LeeZao-Zhong SuLuni EmdadDevanand SarkarPaul B. Fisher. (2006)
Astrocyte elevated gene-1 (
AEG-1
) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc
. Proceedings of the National Academy of Sciences 103:46, pages 17390-17395.
Crossref
Crossref
Erik S. Knudsen & Karen E. Knudsen. (2016) Retinoblastoma Tumor Suppressor: Where Cancer Meets the Cell Cycle. Experimental Biology and Medicine 231:7, pages 1271-1281.
Crossref
Crossref
M T McCabe, J A Low, M J Imperiale & M L Day. (2006) Human polyomavirus BKV transcriptionally activates DNA methyltransferase 1 through the pRb/E2F pathway. Oncogene 25:19, pages 2727-2735.
Crossref
Crossref
Paul A. Khavari. (2006) Modelling cancer in human skin tissue. Nature Reviews Cancer 6:4, pages 270-280.
Crossref
Crossref
Elizabeth S. Yeh, Brian O. Lew & Anthony R. Means. (2006) The Loss of PIN1 Deregulates Cyclin E and Sensitizes Mouse Embryo Fibroblasts to Genomic Instability. Journal of Biological Chemistry 281:1, pages 241-251.
Crossref
Crossref
Gitta Goessel, Michael Quante, William C. Hahn, Hideki Harada, Steffen Heeg, Yasir Suliman, Michaela Doebele, Alexander von Werder, Christine Fulda, Hiroshi Nakagawa, Anil K. Rustgi, Hubert E. Blum & Oliver G. Opitz. (2005) Creating oral squamous cancer cells: A cellular model of oral–esophageal carcinogenesis. Proceedings of the National Academy of Sciences 102:43, pages 15599-15604.
Crossref
Crossref