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Redox Report
Communications in Free Radical Research
Volume 17, 2012 - Issue 1
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Review article

NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns

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Pages 28-46 | Published online: 19 Jul 2013

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Jinzi Wu, Zhen Jin, Hong Zheng & Liang-Jun Yan. (2016) Sources and implications of NADH/NAD+ redox imbalance in diabetes and its complications. Diabetes, Metabolic Syndrome and Obesity 9, pages 145-153.
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Juan-Manuel Hernandez-Martinez, Caroline M. Forrest, L. Gail Darlington, Robert A. Smith & Trevor W. Stone. (2017) Quinolinic acid induces neuritogenesis in SH-SY5Y neuroblastoma cells independently of NMDA receptor activation. European Journal of Neuroscience 45:5, pages 700-711.
Crossref
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D. A. Knorre & F. F. Severin. (2016) Uncouplers of oxidation and phosphorylation as antiaging compounds. Biochemistry (Moscow) 81:12, pages 1438-1444.
Crossref
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Crossref
Samuel W. Caito & Michael Aschner. (2016) NAD + Supplementation Attenuates Methylmercury Dopaminergic and Mitochondrial Toxicity in Caenorhabditis Elegans . Toxicological Sciences 151:1, pages 139-149.
Crossref
Dong-Xia Zhang, Jia-Ping Zhang, Jiong-Yu Hu & Yue-Sheng Huang. (2016) The potential regulatory roles of NAD+ and its metabolism in autophagy. Metabolism 65:4, pages 454-462.
Crossref
Kevin E. Conley, Amir S. Ali, Brandon Flores, Sharon A. Jubrias & Eric G. Shankland. (2016) Mitochondrial NAD(P)H In vivo: Identifying Natural Indicators of Oxidative Phosphorylation in the 31P Magnetic Resonance Spectrum. Frontiers in Physiology 7.
Crossref
Ting Wang & Yasuhiro Takikawa. (2015) Carnosic acid protects normal mouse hepatocytes against H 2 O 2 ‐induced cytotoxicity via sirtuin 1‐mediated signaling . Hepatology Research 46:2, pages 239-246.
Crossref
Anna Henningham, Simon Döhrmann, Victor Nizet & Jason N. Cole. (2015) Mechanisms of group A Streptococcus resistance to reactive oxygen species . FEMS Microbiology Reviews 39:4, pages 488-508.
Crossref
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Crossref
Juan A Godoy, Juvenal A Rios, Juan M Zolezzi, Nady Braidy & Nibaldo C Inestrosa. (2014) Signaling pathway cross talk in Alzheimer’s disease. Cell Communication and Signaling 12:1.
Crossref
Juan A. Godoy, Juan M. Zolezzi, Nady Braidy & Nibaldo C. Inestrosa. (2014) Role of Sirt1 During the Ageing Process: Relevance to Protection of Synapses in the Brain. Molecular Neurobiology 50:3, pages 744-756.
Crossref
Huijuan Jia, Wanping Aw, Manaka Hanate, Shoko Takahashi, Kenji Saito, Hiroshi Tanaka, Masaru Tomita & Hisanori Kato. (2014) Multi-faceted integrated omics analysis revealed parsley (Petroselinum crispum) as a novel dietary intervention in dextran sodium sulphate induced colitic mice. Journal of Functional Foods 11, pages 438-448.
Crossref
Ana Laura Colín-González, Marisol Maya-López, José Pedraza-Chaverrí, Syed F. Ali, Anahí Chavarría & Abel Santamaría. (2014) The Janus faces of 3-hydroxykynurenine: Dual redox modulatory activity and lack of neurotoxicity in the rat striatum. Brain Research 1589, pages 1-14.
Crossref
Xingyin Liu, Christina Greer & Julie Secombe. (2014) KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress. PLoS Genetics 10:10, pages e1004676.
Crossref
Adrian C. Williams & Robin I.M. Dunbar. (2014) Big brains, meat, tuberculosis and the nicotinamide switches: Co-evolutionary relationships with modern repercussions on longevity and disease?. Medical Hypotheses 83:1, pages 79-87.
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Ling Liu, Ping Wang, Xinwei Liu, Dongwei He, Canxin Liang & Ying Yu. (2014) Exogenous NAD + supplementation protects H9c2 cardiac myoblasts against hypoxia/reoxygenation injury via Sirt1-p53 pathway . Fundamental & Clinical Pharmacology 28:2, pages 180-189.
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Min Liu, Jiantao Ye, Si Gao, Wei Fang, Hong Li, Biao Geng, Jian Zou, Xi Chen, Shaorui Chen, Luankun Zhang, Zhongbao Yue, Yunzi Ma, Hui Gao, Zhuoming Li & Peiqing Liu. (2014) Salvianolic acid B protects cardiomyocytes from angiotensin II-induced hypertrophy via inhibition of PARP-1. Biochemical and Biophysical Research Communications 444:3, pages 346-353.
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James N Cobley, George K Sakellariou, Scott Murray, Sarah Waldron, Warren Gregson, Jatin G Burniston, James P Morton, Lesley A Iwanejko & Graeme L Close. (2013) Lifelong endurance training attenuates age-related genotoxic stress in human skeletal muscle. Longevity & Healthspan 2:1.
Crossref
Nady Braidy, Chai K. Lim, Ross Grant, Bruce J. Brew & Gilles J. Guillemin. (2013) Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis. Brain Research 1537, pages 267-272.
Crossref
Adrian C. WilliamsRobin I.M. Dunbar. (2013) Big Brains, Meat, Tuberculosis, and the Nicotinamide Switches: Co-Evolutionary Relationships with Modern Repercussions?. International Journal of Tryptophan Research 6, pages IJTR.S12838.
Crossref
Rafael Lugo-Huitrón, Perla Ugalde Muñiz, Benjamin Pineda, José Pedraza-Chaverrí, Camilo Ríos & Verónica Pérez-de la Cruz. (2013) Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets. Oxidative Medicine and Cellular Longevity 2013, pages 1-14.
Crossref
Jingping Liu, Dan Wang, Younan Chen, Hongjie Sun, Sirong He, Chengshi Wang, Guang Yang, Meimei Shi, Jie Zhang, Yan Ren, Li Wang, Yanrong Lu & Jingqiu Cheng. (2013) 1H NMR-based metabonomic analysis of serum and urine in a nonhuman primate model of diabetic nephropathy. Molecular BioSystems 9:11, pages 2645.
Crossref
Ana Laura Colín-González, Perla D. Maldonado & Abel Santamaría. (2013) 3-Hydroxykynurenine: An intriguing molecule exerting dual actions in the Central Nervous System. NeuroToxicology 34, pages 189-204.
Crossref
H.A.M. Mutsaers, M.J.G. Wilmer, D. Reijnders, J. Jansen, P.H.H. van den Broek, M. Forkink, E. Schepers, G. Glorieux, R. Vanholder, L.P. van den Heuvel, J.G. Hoenderop & R. Masereeuw. (2013) Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1832:1, pages 142-150.
Crossref
Jeong-Soo Park. (2012) Safe Nuclear Factor-kappa B Inhibitor for Cachexia Management. Journal of Korean Biological Nursing Science 14:2, pages 129-138.
Crossref

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