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Original Article

Patient characteristics, drug adherence patterns, and hypoglycemia costs for patients with type 2 diabetes mellitus newly initiated on exenatide or insulin glargine

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Pages 777-786 | Accepted 30 Dec 2008, Published online: 10 Feb 2009

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Read on this site (20)

Daniel C. Beachler, Gail Fernandes, Gaurav Deshpande, Jamileh Jemison, Jennifer G. Lyons, Stephan Lanes, Jinan Liu & Annie McNeill. (2018) Patient and prescriber characteristics among patients with type 2 diabetes mellitus continuing or discontinuing sulfonylureas following insulin initiation: data from a large commercial database. Current Medical Research and Opinion 34:6, pages 1061-1069.
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Wendy S. Lane, James Weatherall, Jens Gundgaard & Richard F. Pollock. (2018) Insulin degludec versus insulin glargine U100 for patients with type 1 or type 2 diabetes in the US: a budget impact analysis with rebate tables. Journal of Medical Economics 21:2, pages 144-151.
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Jieruo Liu, Rosa Wang, Michael L. Ganz, Yurek Paprocki, Doron Schneider & James Weatherall. (2018) The burden of severe hypoglycemia in type 2 diabetes. Current Medical Research and Opinion 34:1, pages 179-186.
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Mirko V Sikirica, Alan A Martin, Robert Wood, Andrea Leith, James Piercy & Victoria Higgins. (2017) Reasons for discontinuation of GLP1 receptor agonists: data from a real-world cross-sectional survey of physicians and their patients with type 2 diabetes. Diabetes, Metabolic Syndrome and Obesity 10, pages 403-412.
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James Weatherall, Lisa Bloudek & Sarah Buchs. (2017) Budget impact of treating commercially insured type 1 and type 2 diabetes patients in the United States with insulin degludec compared to insulin glargine. Current Medical Research and Opinion 33:2, pages 231-238.
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Volker Foos, Nebibe Varol, Bradley H. Curtis, Kristina S. Boye, David Grant, James L. Palmer & Phil McEwan. (2015) Economic impact of severe and non-severe hypoglycemia in patients with Type 1 and Type 2 diabetes in the United States. Journal of Medical Economics 18:6, pages 420-432.
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Stuart Samuel, Devesh Goswami, Kenny Shum, Kristina S. Boye, Badri Rengarajan, Bradley Curtis & Sarah E. Curtis. (2015) A model of mild hypoglycemia. Current Medical Research and Opinion 31:4, pages 633-641.
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Michael L. Ganz, Neil S. Wintfeld, Qian Li, Yuan-Chi Lee, Elyse Gatt & Joanna C. Huang. (2014) Severe hypoglycemia rates and associated costs among type 2 diabetics starting basal insulin therapy in the United States. Current Medical Research and Opinion 30:10, pages 1991-2000.
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Sheila A Doggrell. (2013) Exenatide extended-release; clinical trials, patient preference, and economic considerations. Patient Preference and Adherence 7, pages 35-45.
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Claes-Göran Östenson, Stephan Matthaei, Matthew Reaney, Thure Krarup, Bruno Guerci, Jacek Kiljanski, Carole Salaun-Martin, Hélène Sapin, David Bruhn, Chantal Mathieu & Michael Theodorakis. (2013) Treatment outcomes after initiation of exenatide twice daily or insulin in clinical practice: 12-month results from CHOICE in six European countries. Diabetes, Metabolic Syndrome and Obesity 6, pages 171-185.
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Meryl Brod, Azhar Rana & Anthony H. Barnett. (2012) Adherence patterns in patients with type 2 diabetes on basal insulin analogues: missed, mistimed and reduced doses. Current Medical Research and Opinion 28:12, pages 1933-1946.
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Eric Q. Wu, Steve Zhou, Andrew Yu, Mei Lu, Hari Sharma, Jasvinder Gill & Thomas Graf. (2012) Outcomes Associated with Post-Discharge Insulin Continuity in US Patients with Type 2 Diabetes Mellitus Initiating Insulin in the Hospital. Hospital Practice 40:4, pages 40-48.
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Morgan Bron, Maryna Marynchenko, Hongbo Yang, Andrew P. Yu & Eric Q. Wu. (2012) Hypoglycemia, Treatment Discontinuation, and Costs in Patients with Type 2 Diabetes Mellitus on Oral Antidiabetic Drugs. Postgraduate Medicine 124:1, pages 124-132.
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Richard M. Bergenstal, Louis P. Garrison$suffix/text()$suffix/text(), Lesley-Ann Miller, Likun Hou, Amy Blickensderfer, Anthony Zagar, Shelley Stanley, Anuj Bhargava, Rolin Wade & William H. Herman. (2011) Exenatide BID Observational Study (ExOS): results for primary and secondary endpoints of a prospective research study to evaluate the clinical effectiveness of exenatide BID use in patients with type 2 diabetes in a real-world setting. Current Medical Research and Opinion 27:12, pages 2335-2342.
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Richard M. Bergenstal, Louis P. Garrison$suffix/text()$suffix/text(), Matthew Wintle, Amy Blickensderfer, Rolin Wade, Likun Hou, Lesley-Ann Miller, Jamie Scism-Bacon, Anthony Zagar, Derek Misurski & William H. Herman. (2011) Exenatide bid observational study (ExOS): baseline population characteristics of a prospective research study to evaluate the clinical effectiveness of exenatide bid use in patients with type 2 diabetes in a real-world setting. Current Medical Research and Opinion 27:3, pages 531-540.
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Onur Baser, Wenhui Wei, Erdem Baser & Lin Xie. (2011) Clinical and economic outcomes in patients with type 2 diabetes initiating insulin glargine disposable pen versus exenatide BID. Journal of Medical Economics 14:6, pages 673-680.
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Machaon MK Bonafede, Anupama Kalsekar, Manjiri Pawaskar, Kimberly M Ruiz, Amelito M Torres, Karen R Kelly & Suellen M Curkendall. (2010) A retrospective database analysis of insulin use patterns in insulin-naïve patients with type 2 diabetes initiating basal insulin or mixtures. Patient Preference and Adherence 4, pages 147-156.
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Thomas Blevins, Jenny Han, Dawn Nicewarner, Steve Chen, Juliana H. A. Oliveira & Stephen Aronoff. (2010) Exenatide is Non-inferior to Insulin in Reducing HbA1c: An Integrated Analysis of 1423 Patients with Type 2 Diabetes. Postgraduate Medicine 122:3, pages 118-128.
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Carol H. Wysham. (2010) New Perspectives in Type 2 Diabetes, Cardiovascular Risk, and Treatment Goals. Postgraduate Medicine 122:3, pages 52-60.
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Li Wang, Xiangyang Liu, Wenjuan Yang, Jingbo Lai, Xinwen Yu, Jianrong Liu, Xiling Gao, Jie Ming, Kaiyan Ma, Jing Xu, Zhufang Tian, Qingzhen He & Qiuhe Ji. (2020) Comparison of Blood Glucose Variability Between Exenatide and Biphasic Insulin Aspart 30 in Chinese Participants with Type 2 Diabetes Inadequately Controlled with Metformin Monotherapy: A Multicenter, Open-Label, Randomized Trial. Diabetes Therapy 11:10, pages 2313-2328.
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Thomas Wilke, Sabrina Mueller, Andreas Fuchs, Margit S. Kaltoft, Stefan Kipper & Malgorzata Cel. (2020) Diabetes-Related Effectiveness and Cost of Liraglutide or Insulin in German Patients with Type 2 Diabetes: A 5-Year Retrospective Claims Analysis. Diabetes Therapy 11:10, pages 2357-2370.
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Asnakew Achaw Ayele, Henok Getachew Tegegn, Tadesse Awoke Ayele & Mohammed Biset Ayalew. (2019) Medication regimen complexity and its impact on medication adherence and glycemic control among patients with type 2 diabetes mellitus in an Ethiopian general hospital. BMJ Open Diabetes Research & Care 7:1, pages e000685.
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Shuyan Gu, Xiaoyong Wang, Qing Qiao, Weiguo Gao, Jian Wang & Hengjin Dong. (2017) Cost‐effectiveness of exenatide twice daily vs insulin glargine as add‐on therapy to oral antidiabetic agents in patients with type 2 diabetes in China. Diabetes, Obesity and Metabolism 19:12, pages 1688-1697.
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Samuel StolpeMichel A. KroesNeil WebbTami Wisniewski. (2016) A Systematic Review of Insulin Adherence Measures in Patients with Diabetes. Journal of Managed Care & Specialty Pharmacy 22:11, pages 1224-1246.
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Qing Qiao, Susan Grandy, Josh Hiller & Karel Kostev. (2016) Clinical and Patient-Related Variables Associated with Initiating GLP-1 Receptor Agonist Therapy in Type 2 Diabetes Patients in Primary Care in Germany. PLOS ONE 11:3, pages e0152281.
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Thomas Wilke, Sabrina Mueller, Antje Groth, Bjoern Berg, Andreas Fuchs, Mirko Sikirica, John Logie, Alan Martin & Ulf Maywald. (2015) Non-Persistence and Non-Adherence of Patients with Type 2 Diabetes Mellitus in Therapy with GLP-1 Receptor Agonists: A Retrospective Analysis. Diabetes Therapy 7:1, pages 105-124.
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Sang Youl Rhee, Soo Min Hong, Suk Chon, Kyu Jeung Ahn, Sung Hoon Kim, Sei Hyun Baik, Yong Soo Park, Moon Suk Nam, Kwan Woo Lee, Jeong-Taek Woo & Young Seol Kim. (2016) Hypoglycemia and Medical Expenses in Patients with Type 2 Diabetes Mellitus: An Analysis Based on the Korea National Diabetes Program Cohort. PLOS ONE 11:2, pages e0148630.
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Kam CapocciaPeggy S. OdegardNancy Letassy. (2015) Medication Adherence With Diabetes Medication. The Diabetes Educator 42:1, pages 34-71.
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Philip Levin, Steve Zhou, Emily Durden, Amanda M. Farr, Jasvinder Gill & Wenhui Wei. (2016) Clinical and Economic Outcomes Associated With the Timing of Initiation of Basal Insulin in Patients With Type 2 Diabetes Mellitus Previously Treated With Oral Antidiabetes Drugs. Clinical Therapeutics 38:1, pages 110-121.
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Paul L. McCormack. (2014) Exenatide Twice Daily: A Review of Its Use in the Management of Patients with Type 2 Diabetes Mellitus. Drugs 74:3, pages 325-351.
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Manjiri Pawaskar, Machaon Bonafede, Barbara Johnson, Robert Fowler, Gregory Lenhart & Byron Hoogwerf. (2013) Medication utilization patterns among type 2 diabetes patients initiating Exenatide BID or insulin glargine: a retrospective database study. BMC Endocrine Disorders 13:1.
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Jaime A. Davidson. (2013) Incretin-Based Therapies: Focus on Effects Beyond Glycemic Control Alone. Diabetes Therapy 4:2, pages 221-238.
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Robert R. Henry, Julio Rosenstock, Douglas K. Logan, Thomas R. Alessi, Kenneth Luskey & Michelle A. Baron. (2013) Randomized Trial of Continuous Subcutaneous Delivery of Exenatide by ITCA 650 Versus Twice-Daily Exenatide Injections in Metformin-Treated Type 2 Diabetes. Diabetes Care 36:9, pages 2559-2565.
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P Karagianni, SA Polyzos, N Kartali, I Zografou & C Sambanis. (2013) Comparative efficacy of exenatide versus insulin glargine on glycemic control in type 2 diabetes mellitus patients inadequately treated with metformin monotherapy. Advances in Medical Sciences 58:1, pages 38-43.
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Robert R. Henry, Douglas Logan, Thomas Alessi & Michelle A. Baron. (2013) A Randomized, Open-Label, Multicenter, 4-Week Study to Evaluate the Tolerability and Pharmacokinetics of ITCA 650 in Patients With Type 2 Diabetes☆☆This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.. Clinical Therapeutics 35:5, pages 634-645.e1.
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Stephan Matthaei, Matthew Reaney, Chantal Mathieu, Claes-Göran Östenson, Thure Krarup, Bruno Guerci, Jacek Kiljanski, Helmut Petto, David Bruhn & Michael Theodorakis. (2012) Patients with Type 2 Diabetes Initiating Exenatide Twice Daily or Insulin in Clinical Practice: CHOICE Study. Diabetes Therapy 3:1.
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Eric Q. Wu, Steve Zhou, Andrew Yu, Mei Lu, Hari Sharma, Jasvinder Gill & Thomas Graf. (2012) Outcomes Associated With Insulin Therapy Disruption After Hospital Discharge Among Patients with Type 2 Diabetes Mellitus who Had Used Insulin Before and During Hospitalization. Endocrine Practice 18:5, pages 651-659.
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