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Review

Fast-dissolving intraoral drug delivery systems

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Pages 981-986 | Published online: 25 Feb 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Eman Magdy Maher, Ahmed Mahmoud Abdelhaleem Ali, Heba Farouk Salem & Ahmed Abdelbary Abdelrahman. (2016) In vitro/in vivo evaluation of an optimized fast dissolving oral film containing olanzapine co-amorphous dispersion with selected carboxylic acids. Drug Delivery 23:8, pages 3088-3100.
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Motaz Farid, Doaa Ahmed El-Setouhy, Mohamed Ahmed El-Nabarawi & Tahany El-Bayomi. (2016) Particle engineering/different film approaches for earlier absorption of meloxicam. Drug Delivery 23:7, pages 2309-2317.
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Felipe L Lopez, Terry B Ernest, Catherine Tuleu & Mine Orlu Gul. (2015) Formulation approaches to pediatric oral drug delivery: benefits and limitations of current platforms. Expert Opinion on Drug Delivery 12:11, pages 1727-1740.
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Muhammad Hanif, Muhammad Zaman & Vesh Chaurasiya. (2015) Polymers used in buccal film: a review. Designed Monomers and Polymers 18:2, pages 105-111.
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Kai Bin Liew, Yvonne Tze Fung Tan & Kok-Khiang Peh. (2014) Effect of polymer, plasticizer and filler on orally disintegrating film. Drug Development and Industrial Pharmacy 40:1, pages 110-119.
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Shyamali Saha, Catherine Tomaro-Duchesneau, Jamal T Daoud, Maryam Tabrizian & Satya Prakash. (2013) Novel probiotic dissolvable carboxymethyl cellulose films as oral health biotherapeutics: in vitro preparation and characterization. Expert Opinion on Drug Delivery 10:11, pages 1471-1482.
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Lu Xiao, Tao Yi & Ying Liu. (2013) A new self-microemulsifying mouth dissolving film to improve the oral bioavailability of poorly water soluble drugs. Drug Development and Industrial Pharmacy 39:9, pages 1284-1290.
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Ji-Hee Lee, Goeun Choi, Yeon-Ji Oh, Je Won Park, Young Bin Choy, Mung Chul Park, Yeo Joon Yoon, Hwa Jeong Lee, Hee Chul Chang & Jin-Ho Choy. (2012) A nanohybrid system for taste masking of sildenafil. International Journal of Nanomedicine 7, pages 1635-1649.
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Aliasgar Shahiwala. (2011) Formulation approaches in enhancement of patient compliance to oral drug therapy. Expert Opinion on Drug Delivery 8:11, pages 1521-1529.
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Eva Maria Hoffmann, Armin Breitenbach & Jörg Breitkreutz. (2011) Advances in orodispersible films for drug delivery. Expert Opinion on Drug Delivery 8:3, pages 299-316.
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Nitin Saigal, Sanjula Baboota, Alka Ahuja & Javed Ali. (2008) Fast-dissolving intra-oral drug delivery systems. Expert Opinion on Therapeutic Patents 18:7, pages 769-781.
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Articles from other publishers (41)

Cong Xu, Munkh-Amgalan Gantumur, Jialu Sun, Jiahui Guo, Jiage Ma, Zhanmei Jiang, Wan Wang, Jing Zhang, Yue Ma, Juncai Hou & David Julian McClements. (2024) Design of probiotic delivery systems for targeted release. Food Hydrocolloids 149, pages 109588.
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Yuhao Geng & Gareth R. Williams. (2023) Developing and scaling up captopril-loaded electrospun ethyl cellulose fibers for sustained-release floating drug delivery. International Journal of Pharmaceutics 648, pages 123557.
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Indhu Annie Chacko, Gayathri Ramachandran & M.S. Sudheesh. (2023) Unmet technological demands in orodispersible films for age-appropriate paediatric drug delivery. Drug Delivery and Translational Research.
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Nura Brimo, Dilek Çökeliler Serdaroğlu, Tansel Uyar, Busra Uysal, Elif Bahar Çakıcı, Miris Dikmen & Zerrin Canturk. (2023) Novel Electrospun Polymeric Nanofibers Loaded Different Medicaments as Drug Delivery Systems for Regenerative Endodontics. Current Drug Delivery 20:7, pages 992-1014.
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Jiyao Xing, Miao Zhang, Xinlin Liu, Chao Wang, Nannan Xu & Dongming Xing. (2023) Multi-material electrospinning: from methods to biomedical applications. Materials Today Bio 21, pages 100710.
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Mario A. Cano-Vega, Laura M. Arango-Salazar & Rodolfo Pinal. (2023) Tunable Drug Release Rate Using Modular Oral Dosage Forms. Pharmaceutics 15:7, pages 1905.
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Ekapol Limpongsa, Peera Tabboon, Thaned Pongjanyakul & Napaphak Jaipakdee. (2022) Preparation and Evaluation of Directly Compressible Orally Disintegrating Tablets of Cannabidiol Formulated Using Liquisolid Technique. Pharmaceutics 14:11, pages 2407.
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Sana Javed, Amjad Hussain, Pervaiz Akhtar Shah, Syed Atif Raza, Ubaid Ullah Anwer, Rahat Shamim, Fatima Rasool, Muhammad Ahsan Hafiz & Nadeem Irfan Bukhari. (2022) Development of Optimized Sumatriptan–Prochlorperazine Combined Orodispersible Films Without Disintegrant: in vitro, ex vivo and in vivo Characterization. AAPS PharmSciTech 23:5.
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Hye-Ryeong Park, Su Hyun Seok, Kyu-Mok Hwang, Ju-Young Kim, Chun-Woong Park & Eun-Seok Park. (2022) Formulation of sustained-release orodispersible film containing drug–resin complexes of donepezil hydrochloride. Journal of Pharmaceutical Investigation 52:2, pages 259-272.
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Mohammadali Poursharifi Ghourichay, Seyed Hossein Kiaie, Ali Nokhodchi & Yousef Javadzadeh. (2021) Formulation and Quality Control of Orally Disintegrating Tablets (ODTs): Recent Advances and Perspectives. BioMed Research International 2021, pages 1-12.
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Fatima Akbar Sheikh, Muhammad Naeem Aamir, Muhammad Tahir Haseeb, Syed Nasir Abbas Bukhari, Muhammad Farid ul Haq & Naveed Akhtar. (2021) Design, physico-chemical assessment and pharmacokinetics of a non-toxic orodispersible film for potential application in musculo-skeletal disorder. Journal of Drug Delivery Science and Technology 65, pages 102726.
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Maria Mushtaq, Nosheen Fazal & Amna Niaz. (2020) Formulation and Evaluation of Fast-disintegrating Tablets of Flurbiprofen and Metoclopramide. Journal of Pharmaceutical Innovation 16:3, pages 419-438.
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Sanika KOLE, Ashwin KUCHEKAR & Dnyanesh LİMAYE. (2021) Advancements in Formulation Approaches to Pediatric Oral Drug Delivery systems. Hacettepe University Journal of the Faculty of Pharmacy.
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Phuong H.L. Tran, Beom-Jin Lee & Thao T.D. Tran. (2021) Fast-Dissolving Solid Dispersions for the Controlled Release of Poorly Watersoluble Drugs. Current Pharmaceutical Design 27:12, pages 1498-1506.
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Kwadwo Amanor Mfoafo, Masoud Omidian, Charise Dallazem Bertol, Yadollah Omidi & Hossein Omidian. (2021) Neonatal and pediatric oral drug delivery: Hopes and hurdles. International Journal of Pharmaceutics 597, pages 120296.
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Olga Kiefer, Björn Fischer & Jörg Breitkreutz. (2021) Fundamental Investigations into Metoprolol Tartrate Deposition on Orodispersible Films by Inkjet Printing for Individualised Drug Dosing. Pharmaceutics 13:2, pages 247.
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Yuhao Geng, Fenglei Zhou & Gareth R. Williams. (2021) Developing and scaling up fast-dissolving electrospun formulations based on poly(vinylpyrrolidone) and ketoprofen. Journal of Drug Delivery Science and Technology 61, pages 102138.
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Bo Sun, Weijun Wang, Zhibin He, Min Zhang, Fangong Kong & Mohini Sain. (2020) Biopolymer Substrates in Buccal Drug Delivery: Current Status and Future Trend. Current Medicinal Chemistry 27:10, pages 1661-1669.
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Asli Celebioglu & Tamer Uyar. (2020) Hydrocortisone/cyclodextrin complex electrospun nanofibers for a fast-dissolving oral drug delivery system. RSC Medicinal Chemistry 11:2, pages 245-258.
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Asli Celebioglu & Tamer Uyar. (2019) Metronidazole/Hydroxypropyl-β-Cyclodextrin inclusion complex nanofibrous webs as fast-dissolving oral drug delivery system. International Journal of Pharmaceutics 572, pages 118828.
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R. Bernasconi, N. Favara, S. Turri & L. Magagnin. (2019) Electrodeposited Nanoporous Polypyrrole Layers for Controlled Drug Release. Journal of The Electrochemical Society 166:10, pages G122-G129.
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V.V Pande, A.A. Patel, V.P. Patel & P.V. Khedkar. (2018) FORMULATION AND EVALUATION OF FAST DISSOLVING FILM OF FOSINOPRIL. INDIAN DRUGS 55:12, pages 34-40.
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Muhammad Zaman & Muhammad Hanif. (2018) In vitro and ex vivo assessment of hydrophilic polymer- and plasticizer-based thin buccal films designed by using central composite rotatable design for the delivery of meloxicam. Advances in Polymer Technology 37:6, pages 1823-1836.
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Vipul D. Prajapati, Anita M. Chaudhari, Abhishek K. Gandhi & Pankaj Maheriya. (2018) Pullulan based oral thin film formulation of zolmitriptan: Development and optimization using factorial design. International Journal of Biological Macromolecules 107, pages 2075-2085.
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Sara Bahrainian, Mohammadreza Abbaspour, Maryam Kouchak & Pooria Taghavi Moghadam. (2016) A Review on Fast Dissolving Systems: From Tablets to Nanofibers. Jundishapur Journal of Natural Pharmaceutical Products 12:2.
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Sara Bahrainian, Mohammadreza Abbaspour, Maryam Kouchak & Pooria Taghavi Moghadam. (2016) A Review on Fast Dissolving Systems: From Tablets to Nanofibers. Jundishapur Journal of Natural Pharmaceutical Products InPress:InPress.
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Raphael Krampe, Daniel Sieber, Miriam Pein-Hackelbusch & Jörg Breitkreutz. (2016) A new biorelevant dissolution method for orodispersible films. European Journal of Pharmaceutics and Biopharmaceutics 98, pages 20-25.
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U. Eranka Illangakoon, Hardyal Gill, Gemma C. Shearman, Maryam Parhizkar, Sunthar Mahalingam, Nicholas P. Chatterton & Gareth R. Williams. (2014) Fast dissolving paracetamol/caffeine nanofibers prepared by electrospinning. International Journal of Pharmaceutics 477:1-2, pages 369-379.
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Jong-Il Kim, Sang-Min Cho, Jing-Hao Cui, Qing-Ri Cao, Euichaul Oh & Beom-Jin Lee. (2013) In vitro and in vivo correlation of disintegration and bitter taste masking using orally disintegrating tablet containing ion exchange resin-drug complex. International Journal of Pharmaceutics 455:1-2, pages 31-39.
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Birgit J. Teubl, Markus Absenger, Eleonore Fröhlich, Gerd Leitinger, Andreas Zimmer & Eva Roblegg. (2013) The oral cavity as a biological barrier system: Design of an advanced buccal in vitro permeability model. European Journal of Pharmaceutics and Biopharmaceutics 84:2, pages 386-393.
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Yeon-Ji Oh, Goeun Choi, Young Bin Choy, Je Won Park, Jung Hyun Park, Hwa Jeong Lee, Yeo Joon Yoon, Hee Chul Chang & Jin-Ho Choy. (2013) AripiprazoleMontmorillonite: A New Organic-Inorganic Nanohybrid Material for Biomedical Applications. Chemistry - A European Journal 19:15, pages 4869-4875.
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Xiaoqiang Li, Muzafar A. Kanjwal, Lin Lin & Ioannis S. Chronakis. (2013) Electrospun polyvinyl-alcohol nanofibers as oral fast-dissolving delivery system of caffeine and riboflavin. Colloids and Surfaces B: Biointerfaces 103, pages 182-188.
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Xiaoqiang Li, Lin Lin, Yanan Zhu, Wanwan Liu, Tianshi Yu & Mingqiao Ge. (2013) Preparation of ultrafine fast-dissolving cholecalciferol-loaded poly(vinyl pyrrolidone) fiber mats via electrospinning. Polymer Composites 34:2, pages 282-287.
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Johannes Kraemer, Jayachandar Gajendran, Alexis Guillot, Julian Schichtel & Akif Tuereli. (2012) Dissolution testing of orally disintegrating tablets. Journal of Pharmacy and Pharmacology 64:7, pages 911-918.
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Jing Quan, Yang Yu, Christopher Branford-White, Gareth R. Williams, Deng-Guang Yu, Wei Nie & Li-Min Zhu. (2011) Preparation of ultrafine fast-dissolving feruloyl-oleyl-glycerol-loaded polyvinylpyrrolidone fiber mats via electrospinning. Colloids and Surfaces B: Biointerfaces 88:1, pages 304-309.
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Bhatu Badgujar & Atish Mundada. (2011) The technologies used for developing orally disintegrating tablets: A review. Acta Pharmaceutica 61:2, pages 117-139.
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João F. Pinto. (2010) Site-specific drug delivery systems within the gastro-intestinal tract: From the mouth to the colon. International Journal of Pharmaceutics 395:1-2, pages 44-52.
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Deng-Guang Yu, Wei Nie, Li-Min Zhu & Christopher Branford-White. (2010) Fast Dissolution Nanofiber Membrane of Ferulic Acid Prepared Using Electrospinning. Fast Dissolution Nanofiber Membrane of Ferulic Acid Prepared Using Electrospinning.
Deng-Guang Yu, Xia-Xia Shen, Chris Branford-White, Kenneth White, Li-Min Zhu & S W Annie Bligh. (2009) Oral fast-dissolving drug delivery membranes prepared from electrospun polyvinylpyrrolidone ultrafine fibers. Nanotechnology 20:5, pages 055104.
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Aditya Dinge & Mangal Nagarsenker. (2008) Formulation and Evaluation of Fast Dissolving Films for Delivery of Triclosan to the Oral Cavity. AAPS PharmSciTech 9:2, pages 349-356.
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F Ndindayino, C Vervaet, G Van den Mooter & J.P Remon. (2002) Bioavailability of hydrochlorothiazide from isomalt-based moulded tablets. International Journal of Pharmaceutics 246:1-2, pages 199-202.
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