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Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015)

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Pages 309-322 | Received 29 Nov 2015, Accepted 21 Jan 2016, Published online: 16 Feb 2016

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Hyun Seung Ban, Yoshikazu Uto & Hiroyuki Nakamura. (2021) Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2016–2020). Expert Opinion on Therapeutic Patents 31:5, pages 387-397.
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Abdul Rahman, Prashanth N, Nippu B N, H M Kumaraswamy, A N Rajeshwara & N D Satyanarayan. (2022) Synthesis and anticancer screening of some novel Pd-catalysed 3-methyl indole based analogues on Mia PaCa-2 cell line. Journal of Molecular Structure 1264, pages 133211.
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Josh W. DiGiacomo & Daniele M. Gilkes. (2018) Tumor Hypoxia As an Enhancer of Inflammation-Mediated Metastasis: Emerging Therapeutic Strategies. Targeted Oncology 13:2, pages 157-173.
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A. Al-Soudi, M.H. Kaaij & S.W. Tas. (2017) Endothelial cells: From innocent bystanders to active participants in immune responses. Autoimmunity Reviews 16:9, pages 951-962.
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Sanghyuck Lee, Oh Seok Kwon, Chang-Soo Lee, Misun Won, Hyun Seung Ban & Choon Sup Ra. (2017) Synthesis and biological evaluation of kresoxim-methyl analogues as novel inhibitors of hypoxia-inducible factor (HIF)-1 accumulation in cancer cells. Bioorganic & Medicinal Chemistry Letters 27:13, pages 3026-3029.
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Alejandro Roman-Gonzalez & Camilo Jimenez. (2017) Malignant pheochromocytoma–paraganglioma. Current Opinion in Endocrinology & Diabetes and Obesity 24:3, pages 174-183.
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Xiaobo Zhou, Ming Chen, Zhiyuan Zheng, Guo-Yuan Zhu, Zhi-Hong Jiang & Li-Ping Bai. (2017) Synthesis and evaluation of novel 12-aryl berberine analogues with hypoxia-inducible factor-1 inhibitory activity. RSC Advances 7:43, pages 26921-26929.
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F. Morinet, M. Parent, S. Pillet, M. Koken, C. Lebbé & C. Capron. (2017) Hypoxia inducible factor one alpha and human viral pathogens. Current Research in Translational Medicine 65:1, pages 7-9.
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Shinichiro Fuse, Toshiaki Ohuchi, Yasunobu Asawa, Shinichi Sato & Hiroyuki Nakamura. (2016) Development of 1-aryl-3-furanyl/thienyl-imidazopyridine templates for inhibitors against hypoxia inducible factor (HIF)-1 transcriptional activity. Bioorganic & Medicinal Chemistry Letters 26:24, pages 5887-5890.
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Hyun Seung Ban, Xuezhen Xu, Kusik Jang, Inhyub Kim, Bo-Kyung Kim, Kyeong Lee & Misun Won. (2016) A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration. PLOS ONE 11:9, pages e0162568.
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A.I. Karseladze. (2016) Intraepithelial ischemia is a principal factor promoting cancerization of the covering epithelial tissues. Medical Hypotheses 94, pages 154-160.
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Sarah E. Corcoran & Luke A.J. O’Neill. (2016) HIF1α and metabolic reprogramming in inflammation. Journal of Clinical Investigation 126:10, pages 3699-3707.
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Hyun Seung Ban, Ravi Naik, Hwan Mook Kim, Bo-Kyung Kim, Hongsub Lee, Inhyub Kim, Heechul Ahn, Yerin Jang, Kyusik Jang, Yumi Eo, Kyung Bin Song, Kyeong Lee & Misun Won. (2016) Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes. Bioconjugate Chemistry 27:8, pages 1911-1920.
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Susan Hua & Thilani H. Dias. (2016) Hypoxia-Inducible Factor (HIF) as a Target for Novel Therapies in Rheumatoid Arthritis. Frontiers in Pharmacology 7.
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