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Review

Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections

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Pages 267-283 | Published online: 17 Jan 2008

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Rajesh Chavan, Vineet Zope, Nilesh Chavan, Kiran Patil, Ravindra Yeole, Sachin Bhagwat & Mahesh Patel. (2021) Assessment of the in vitro cytochrome P450 (CYP) inhibition potential of nafithromycin, a next generation lactone ketolide antibiotic. Xenobiotica 51:3, pages 251-261.
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Nafsika H Georgopapadakou. (2014) The wobbly status of ketolides: where do we stand?. Expert Opinion on Investigational Drugs 23:10, pages 1313-1319.
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Despoina Koulenti, Elena Xu, Andrew Song, Isaac Yin Sum Mok, Drosos E. Karageorgopoulos, Apostolos Armaganidis, Sotirios Tsiodras & Jeffrey Lipman. (2020) Emerging Treatment Options for Infections by Multidrug-Resistant Gram-Positive Microorganisms. Microorganisms 8:2, pages 191.
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Miljana Z. Jovandaric & Svetlana J. Milenkovic. 2019. Selected Topics in Myasthenia Gravis. Selected Topics in Myasthenia Gravis.
Jian-Ming He, Shi-Chang Sun, Zhong-Lin Sun, Jie-Tao Chen & Qing Mu. (2019) Isovalerylshikonin, a new resistance-modifying agent from Arnebia euchroma, supresses antimicrobial resistance of drug-resistant Staphylococcus aureus. International Journal of Antimicrobial Agents 53:1, pages 70-73.
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Françoise van Bambeke, Marie-Paule Mingeot-Leclercq, Youri Glupczynski & Paul M. Tulkens. 2017. Infectious Diseases. Infectious Diseases 1162 1180.e1 .
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V. Samuel Raj, Tarani Kanta Barman, Vandana Kalia, Kedar Purnapatre, Smita Dube, Ramkumar G., Pragya Bhateja, Tarun Mathur, Tridib Chaira, Dilip J. Upadhyay, Yogesh B. Surase, R. Venkataramanan, Anjan Chakrabarti, Biswajit Das & Pradip K. Bhatnagar. (2014) A Novel Ketolide, RBx 14255, with Activity against Multidrug-Resistant Streptococcus pneumoniae. Antimicrobial Agents and Chemotherapy 58:8, pages 4283-4289.
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Takayuki Katsube, Toshihiro Wajima, Yoshinori Yamano & Yoshitaka Yano. (2014) Pharmacokinetic/Pharmacodynamic Modeling for Concentration-Dependent Bactericidal Activity of a Bicyclolide, Modithromycin. Journal of Pharmaceutical Sciences 103:4, pages 1288-1297.
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Françoise Van Bambeke. 2014. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics 257 278 .
Pulkit Gupta, Krishna Kannan, Alexander S. Mankin & Nora Vázquez-Laslop. (2013) Regulation of Gene Expression by Macrolide-Induced Ribosomal Frameshifting. Molecular Cell 52:5, pages 629-642.
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Akiko Takaya, Yoshiharu Sato, Tatsuma Shoji & Tomoko Yamamoto. (2013) Methylation of 23S rRNA Nucleotide G748 by RlmA II Methyltransferase Renders Streptococcus pneumoniae Telithromycin Susceptible . Antimicrobial Agents and Chemotherapy 57:8, pages 3789-3796.
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Jie-Wei Jiang, Ying Sun, Ying Nie, Hui-Jing Zhi, Xiao-Jin Zhang, Xiang Li, Hao-Peng Sun & Qi-Dong You. (2013) Synthesis and antibacterial evaluation of a novel series of 10-hydroxyl ketolide derivatives. Bioorganic & Medicinal Chemistry Letters 23:11, pages 3452-3457.
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Mariya Morar, Kate Pengelly, Kalinka Koteva & Gerard D. Wright. (2012) Mechanism and Diversity of the Erythromycin Esterase Family of Enzymes. Biochemistry 51:8, pages 1740-1751.
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Ze-Qi Xu, Michael T. Flavin & David A. Eiznhamer. 2012. Antibiotic Discovery and Development. Antibiotic Discovery and Development 181 228 .
Yu-Hong Min, Eun-Jeong Yoon, Ae-Ran Kwon, Mi-Ja Shim & Eung-Chil Choi. (2011) Alterations in regulatory regions of erm(B) genes from clinical isolates of enterococci resistant to telithromycin. Archives of Pharmacal Research 34:12, pages 2149-2154.
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T. Sato, Y. Kawai, H. Matsuda, K. Tateda, S. Kimura, Y. Ishii, K. Yamaguchi & N. Gotoh. (2011) In vitro and in vivo antibacterial activity of modithromycin against streptococci and Haemophilus influenzae. Journal of Antimicrobial Chemotherapy 66:7, pages 1547-1554.
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Takafumi Sato, Kazuhiro Tateda, Soichiro Kimura, Morihiro Iwata, Yoshikazu Ishii & Keizo Yamaguchi. (2011) In Vitro Antibacterial Activity of Modithromycin, a Novel 6,11-Bridged Bicyclolide, against Respiratory Pathogens, Including Macrolide-Resistant Gram-Positive Cocci . Antimicrobial Agents and Chemotherapy 55:4, pages 1588-1593.
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Lisa S. McCoy, Yun Xie & Yitzhak Tor. (2011) Antibiotics that target protein synthesis. Wiley Interdisciplinary Reviews: RNA 2:2, pages 209-232.
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Mirjana Bukvić Krajačić, Miljenko Dumić, Predrag Novak, Mario Cindrić, Sanja Koštrun, Andrea Fajdetić, Sulejman Alihodžić, Karmen Brajša & Nedjeljko Kujundžić. (2011) Discovery of novel ureas and thioureas of 3-decladinosyl-3-hydroxy 15-membered azalides active against efflux-mediated resistant Streptococcus pneumoniae. Bioorganic & Medicinal Chemistry Letters 21:2, pages 853-856.
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Hidetoshi Furuie, Yutaka Saisho, Takayoshi Yoshikawa & Jingoro Shimada. (2010) Intrapulmonary Pharmacokinetics of S-013420, a Novel Bicyclolide Antibacterial, in Healthy Japanese Subjects. Antimicrobial Agents and Chemotherapy 54:2, pages 866-870.
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Françoise Van Bambeke, Youri Glupczynski, Marie-Paule Mingeot-Leclercq & Paul M. Tulkens. 2010. Infectious Diseases. Infectious Diseases 1288 1307 .
Sandrine Lemaire, Françoise Van Bambeke & Paul M. Tulkens. (2009) Cellular Accumulation and Pharmacodynamic Evaluation of the Intracellular Activity of CEM-101, a Novel Fluoroketolide, against Staphylococcus aureus , Listeria monocytogenes , and Legionella pneumophila in Human THP-1 Macrophages . Antimicrobial Agents and Chemotherapy 53:9, pages 3734-3743.
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Drosos E. Karageorgopoulos & Matthew E. Falagas. (2009) New antibiotics: optimal use in current clinical practice. International Journal of Antimicrobial Agents 34, pages S55-S62.
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Mark S. Butler. (2008) Natural products to drugs: natural product-derived compounds in clinical trials. Natural Product Reports 25:3, pages 475.
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