Advanced search
Publication Cover
Expert Opinion on Biological Therapy Volume 6, 2006 - Issue 7
Submit an article Journal homepage
459
Views
72
CrossRef citations to date
0
Altmetric
Technology Evaluation

Application of encapsulated cell technology for retinal degenerative diseases

Weng Tao Neurotech USA, Inc., 6 Blackstone Valley Place, Suite 500, Lincoln, RI 02865, USA. [email protected]
Pages 717-726 | Published online: 29 Jun 2006

Citations (72)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (11)

Federico Rissotto, Riccardo Sacconi, Aurelio Apuzzo, Gloria Oldoni, Emanuele Fusi, Andrea Servillo, Francesco Bandello & Giuseppe Querques. (2023) What is on the horizon for dry age-related macular degeneration drug treatment?. Expert Review of Ophthalmology 18:5, pages 289-301.
Read now
Maryam Ghasemi, Effat Alizadeh, Khatereh Saei Arezoumand, Behzad Fallahi Motlagh & Nosratollah Zarghami. (2018) Ciliary neurotrophic factor (CNTF) delivery to retina: an overview of current research advancements. Artificial Cells, Nanomedicine, and Biotechnology 46:8, pages 1694-1707.
Read now
Vibhuti Agrahari, Vivek Agrahari, Abhirup Mandal, Dhananjay Pal & Ashim K. Mitra. (2017) How are we improving the delivery to back of the eye? Advances and challenges of novel therapeutic approaches. Expert Opinion on Drug Delivery 14:10, pages 1145-1162.
Read now
Jennifer J. Kang-Mieler, Emily Dosmar, Wenqiang Liu & William F. Mieler. (2017) Extended ocular drug delivery systems for the anterior and posterior segments: biomaterial options and applications. Expert Opinion on Drug Delivery 14:5, pages 611-620.
Read now
Henry Klassen. (2016) Stem cells in clinical trials for treatment of retinal degeneration. Expert Opinion on Biological Therapy 16:1, pages 7-14.
Read now
Hongming Chen. (2015) Recent developments in ocular drug delivery. Journal of Drug Targeting 23:7-8, pages 597-604.
Read now
Jennifer J Kang-Mieler, Christian R Osswald & William F Mieler. (2014) Advances in ocular drug delivery: emphasis on the posterior segment. Expert Opinion on Drug Delivery 11:10, pages 1647-1660.
Read now
Mitsuru Nakazawa. (2014) Therapy options for retinitis pigmentosa. Expert Opinion on Orphan Drugs 2:1, pages 37-52.
Read now
Joanne E Sutherland & Megan A Day. (2011) Advantages and disadvantages of molecular testing in ophthalmology. Expert Review of Ophthalmology 6:2, pages 221-245.
Read now
Gordon S Lynch. (2008) Update on emerging drugs for sarcopenia – age-related muscle wasting. Expert Opinion on Emerging Drugs 13:4, pages 655-673.
Read now
Konstantin Petrukhin. (2007) New therapeutic targets in atrophic age-related macular degeneration. Expert Opinion on Therapeutic Targets 11:5, pages 625-639.
Read now

Articles from other publishers (61)

Yeji Ham, Hemal Mehta, Jennifer Kang-Mieler, William F. Mieler & Andrew Chang. (2023) Novel Drug Delivery Methods and Approaches for the Treatment of Retinal Diseases. Asia-Pacific Journal of Ophthalmology 12:4, pages 402-413.
Crossref
Sachiko Imaichi-Kobayashi, Rayan Kassab, Alessandra Piersigilli, Robbie Robertson, Christopher Leonard, Nathaniel Long, Brenda Dean, Matthew Phaneuf & Vincent Ling. (2023) An electrospun macrodevice for durable encapsulation of human cells with consistent secretion of therapeutic antibodies. Biomaterials 298, pages 122123.
Crossref
Yuening Shen, Jianguo Sun & Xinghuai Sun. (2023) Intraocular nano-microscale drug delivery systems for glaucoma treatment: design strategies and recent progress. Journal of Nanobiotechnology 21:1.
Crossref
Emilie Audouard, Fanny Michel, Vanessa Pierroz, Taeuk Kim, Lisa Rousselot, Béatrix Gillet-Legrand, Gaëlle Dufayet-Chauffaut, Peter Buchmann, Michael Florea, Alexander Khel, Kamilya Altynbekova, Claudia Delgaldo, Encarna Escudero, Alejandra Ben Aissa Soler, Nathalie Cartier, Francoise Piguet & Marc Folcher. (2022) Bioelectronic cell-based device provides a strategy for the treatment of the experimental model of multiple sclerosis. Journal of Controlled Release 352, pages 994-1008.
Crossref
Atul Garkal, Priyanka Bangar, Amarjitsing Rajput, Prashant Pingale, Namdev Dhas, Anam Sami, Khushboo Mathur, Shubham Joshi, Sonika Dhuri, Dhaivat Parikh, Srinivas Mutalik & Tejal Mehta. (2022) Long-acting formulation strategies for protein and peptide delivery in the treatment of PSED. Journal of Controlled Release 350, pages 538-568.
Crossref
Yolanda Jiménez-Gómez, David Alba-Molina, Mario Blanco-Blanco, Lorena Pérez-Fajardo, Felisa Reyes-Ortega, Laura Ortega-Llamas, Marta Villalba-González, Ignacio Fernández-Choquet de Isla, Francisco Pugliese, Indira Stoikow & Miguel González-Andrades. (2022) Novel Treatments for Age-Related Macular Degeneration: A Review of Clinical Advances in Sustained Drug Delivery Systems. Pharmaceutics 14:7, pages 1473.
Crossref
Maitri Bhatt & Pravin Shende. (2021) Modulated approaches for strategic transportation of proteins and peptides via ocular route. Journal of Drug Delivery Science and Technology 66, pages 102835.
Crossref
Mariana Y. García-Bermúdez, Kristine K. Freude, Zaynab A. Mouhammad, Peter van Wijngaarden, Keith K. Martin & Miriam Kolko. (2021) Glial Cells in Glaucoma: Friends, Foes, and Potential Therapeutic Targets. Frontiers in Neurology 12.
Crossref
Fabiana Mallone, Marta Sacchetti, Alice Bruscolini, Luca Scuderi, Marco Marenco & Alessandro Lambiase. (2020) Neurotrophic Factors in Glaucoma and Innovative Delivery Systems. Applied Sciences 10:24, pages 9015.
Crossref
Jennifer J. Kang-Mieler, Kayla M. Rudeen, Wenqiang Liu & William F. Mieler. (2020) Advances in ocular drug delivery systems. Eye 34:8, pages 1371-1379.
Crossref
Jennifer J. Kang-Mieler, Kayla M. Rudeen, Wenqiang Liu & William F. Mieler. 2020. Macular Surgery. Macular Surgery 577 591 .
Chandrasekar Ponnusamy, Abimanyu Sugumaran, Venkateshwaran Krishnaswami, Ruckmani Kandasamy & Subramanian Natesan. (2019) Design and development of artemisinin and dexamethasone loaded topical nanodispersion for the effective treatment of age‐related macular degeneration. IET Nanobiotechnology 13:8, pages 868-874.
Crossref
Vrinda Gote, Sadia Sikder, Jeff Sicotte & Dhananjay Pal. (2019) Ocular Drug Delivery: Present Innovations and Future Challenges. Journal of Pharmacology and Experimental Therapeutics 370:3, pages 602-624.
Crossref
Jeremie D. Oliver & Krishna S. Vyas. 2019. Handbook of Tissue Engineering Scaffolds: Volume Two. Handbook of Tissue Engineering Scaffolds: Volume Two 711 720 .
Odysseas Georgiadis, Peter J. Coffey & Lyndon da Cruz. 2019. Cell-Based Therapy for Degenerative Retinal Disease. Cell-Based Therapy for Degenerative Retinal Disease 167 192 .
Marita Pietrucha-Dutczak, Marialaura Amadio, Stefano Govoni, Joanna Lewin-Kowalik & Adrian Smedowski. (2018) The Role of Endogenous Neuroprotective Mechanisms in the Prevention of Retinal Ganglion Cells Degeneration. Frontiers in Neuroscience 12.
Crossref
Deepa Talreja, Siobhan M. Cashman, Bhanu Dasari, Binit Kumar & Rajendra Kumar-Singh. (2018) G-quartet oligonucleotide mediated delivery of functional X-linked inhibitor of apoptosis protein into retinal cells following intravitreal injection. Experimental Eye Research 175, pages 20-31.
Crossref
Paul A. Roberts, Eamonn A. Gaffney, Philip J. Luthert, Alexander J.E. Foss & Helen M. Byrne. (2017) Mathematical models of retinitis pigmentosa: The oxygen toxicity hypothesis. Journal of Theoretical Biology 425, pages 53-71.
Crossref
Rini Rachel Joseph & Subbu S Venkatraman. (2017) Drug delivery to the eye: what benefits do nanocarriers offer?. Nanomedicine 12:6, pages 683-702.
Crossref
. (2017) New Treatment Modalities for Geographic Atrophy. Asia-Pacific Journal of Ophthalmology.
Crossref
. 2016. Drug Delivery. Drug Delivery 305 330 .
Rajinder K. Bhardwaj. 2016. Pharmacology of Ocular Therapeutics. Pharmacology of Ocular Therapeutics 13 35 .
Jayabalan Nirmal & Gaurav K. Jain. 2016. Pharmacology of Ocular Therapeutics. Pharmacology of Ocular Therapeutics 479 515 .
Lihteh Wu. (2015) When is macular edema not macular edema? An update on macular telangiectasia type 2. Taiwan Journal of Ophthalmology 5:4, pages 149-155.
Crossref
Rajni Parthasarathy, K. Martin Chow, Zahra Derafshi, Michael P. Fautsch, John R. Hetling, David W. Rodgers, Louis B. Hersh & David R. Pepperberg. (2015) Reduction of amyloid-beta levels in mouse eye tissues by intra-vitreally delivered neprilysin. Experimental Eye Research 138, pages 134-144.
Crossref
Marie Vandecasteele, Yann-Suhan Senova, Stéphane Palfi & Guillaume P. Dugué. (2015) Potentiel thérapeutique de la neuromodulation optogénétique. médecine/sciences 31:4, pages 404-416.
Crossref
Edoardo Abed, Giovanni Corbo & Benedetto Falsini. (2014) Neurotrophin Family Members as Neuroprotectants in Retinal Degenerations. BioDrugs 29:1, pages 1-13.
Crossref
Ina Meiser, Sabine C. Müller, Friederike Ehrhart, Stephen G. Shirley & Heiko Zimmermann. (2013) A new validation method for clinical grade micro-encapsulation: quantitative high speed video analysis of alginate capsule. Microsystem Technologies 21:1, pages 75-84.
Crossref
Yoo Chun Kim, Bryce Chiang, Xianggen Wu & Mark R. Prausnitz. (2014) Ocular delivery of macromolecules. Journal of Controlled Release 190, pages 172-181.
Crossref
Chikako Harada & Takayuki Harada. 2014. Neuroprotection and Neuroregeneration for Retinal Diseases. Neuroprotection and Neuroregeneration for Retinal Diseases 99 112 .
Sara BrennerEman Elhawy & John Danias. 2013. The Clinical Nanomedicine Handbook. The Clinical Nanomedicine Handbook 195 212 .
M El Sanharawi, E Touchard, R Benard, P Bigey, V Escriou, C Mehanna, M-C Naud, M Berdugo, J-C Jeanny & F Behar-Cohen. (2013) Long-term efficacy of ciliary muscle gene transfer of three sFlt-1 variants in a rat model of laser-induced choroidal neovascularization. Gene Therapy 20:11, pages 1093-1103.
Crossref
Lihteh Wu, Teodoro Evans & J. Fernando Arevalo. (2013) Idiopathic macular telangiectasia type 2 (idiopathic juxtafoveolar retinal telangiectasis type 2A, Mac Tel 2). Survey of Ophthalmology 58:6, pages 536-559.
Crossref
Michael E. Boulton, Sayak K. Mitter, Haripriya Vittal Rao & William A. DunnJrJr. 2013. Retina. Retina 537 552 .
Roshni S. Rainbow & Michael J. Lysaght. 2013. Biomaterials Science. Biomaterials Science 1306 1316 .
Deepak Thassu & Gerald ChaderGerald Chader & Deepak Thassu. 2012. Ocular Drug Delivery Systems. Ocular Drug Delivery Systems 17 40 .
Kang Zhang, Liangfang Zhang & Robert N. Weinreb. (2012) Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma. Nature Reviews Drug Discovery 11:7, pages 541-559.
Crossref
Constance L. Cepko. (2012) Emerging Gene Therapies for Retinal Degenerations. The Journal of Neuroscience 32:19, pages 6415-6420.
Crossref
Krisztina Szabadfi, Tamas Atlasz, Peter Kiss, Dora Reglodi, Aliz Szabo, Krisztina Kovacs, Balint Szalontai, Gyorgy SetaloJr.Jr., Eszter Banki, Katalin Csanaky, Andrea Tamas & Robert Gabriel. (2012) Protective effects of the neuropeptide PACAP in diabetic retinopathy. Cell and Tissue Research 348:1, pages 37-46.
Crossref
Rong Wen, Weng Tao, Yiwen Li & Paul A. Sieving. (2012) CNTF and retina. Progress in Retinal and Eye Research 31:2, pages 136-151.
Crossref
Crystel Bonnet & Aziz El-Amraoui. (2012) Usher syndrome (sensorineural deafness and retinitis pigmentosa). Current Opinion in Neurology 25:1, pages 42-49.
Crossref
C.M. Poloschek & H. Jägle. (2012) Pharmakologische Ansätze in der Therapie erblicher NetzhautdegenerationenPharmacological concepts to treat hereditary retinal degenerations. Der Ophthalmologe 109:2, pages 112-120.
Crossref
Rong Wen, Weng Tao, Lingyu Luo, Deqiang Huang, Konrad Kauper, Paul Stabila, Matthew M. LaVail, Alan M. Laties & Yiwen Li. 2012. Retinal Degenerative Diseases. Retinal Degenerative Diseases 93 99 .
Therese Cronin & Jean Bennett. (2011) Switching on the Lights: The Use of Optogenetics to Advance Retinal Gene Therapy. Molecular Therapy 19:7, pages 1190-1192.
Crossref
Kang ZhangJill J. HopkinsJeffrey S. HeierDavid G. BirchLawrence S. HalperinThomas A. AlbiniDavid M. BrownGlenn J. JaffeWeng Tao & George A. Williams. (2011) Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration. Proceedings of the National Academy of Sciences 108:15, pages 6241-6245.
Crossref
Rong Zhang, Haijuan Zhang, Liang Xu, Ke Ma, Christine Wallrapp & Jost B Jonas. (2011) INTRAVITREAL CELL-BASED PRODUCTION OF GLUCAGON-LIKE PEPTIDE-1. Retina 31:4, pages 785-789.
Crossref
An Truong, Tien Y. Wong & Levon M. Khachigian. (2010) Emerging therapeutic approaches in the management of retinal angiogenesis and edema. Journal of Molecular Medicine 89:4, pages 343-361.
Crossref
Rutledge Ellis-Behnke & Jost B. Jonas. (2011) Redefining tissue engineering for nanomedicine in ophthalmology. Acta Ophthalmologica 89:2, pages e108-e114.
Crossref
Darcie L Moore & Jeffrey L Goldberg. (2010) Four Steps to Optic Nerve Regeneration. Journal of Neuro-Ophthalmology 30:4, pages 347-360.
Crossref
M. El Sanharawi, L. Kowalczuk, E. Touchard, S. Omri, Y. de Kozak & F. Behar-Cohen. (2010) Protein delivery for retinal diseases: From basic considerations to clinical applications. Progress in Retinal and Eye Research 29:6, pages 443-465.
Crossref
H. Dollfus, Y. Perdomo-Trujillo & V. Pelletier. (2010) Rétinopathies pigmentaires. EMC - Ophtalmologie 7:2, pages 1-18.
Crossref
Muhammad Ali Memon & Joseph F RizzoIIIIII. 2010. Ocular Disease. Ocular Disease 590 598 .
Jacob M. Jones, Trevor McFarland & J. Timothy Stout. 2011. Therapeutic Angiogenesis for Vascular Diseases. Therapeutic Angiogenesis for Vascular Diseases 67 80 .
Ying Yang, Saddek Mohand-Said, Aude Danan, Manuel Simonutti, Valérie Fontaine, Emmanuelle Clerin, Serge Picaud, Thierry Léveillard & José-Alain Sahel. (2009) Functional Cone Rescue by RdCVF Protein in a Dominant Model of Retinitis Pigmentosa. Molecular Therapy 17:5, pages 787-795.
Crossref
Saffar Mansoor, Baruch D. Kuppermann & M. Cristina Kenney. (2009) Intraocular Sustained-Release Delivery Systems for Triamcinolone Acetonide. Pharmaceutical Research 26:4, pages 770-784.
Crossref
Brian G. Short. (2008) Safety Evaluation of Ocular Drug Delivery Formulations: Techniques and Practical Considerations. Toxicologic Pathology 36:1, pages 49-62.
Crossref
ROBERT J. WORDINGER & ABBOT F. CLARK. 2008. Ocular Therapeutics. Ocular Therapeutics 87 116 .
ALAN L. WEINER. 2008. Ocular Therapeutics. Ocular Therapeutics 7 43 .
Xuyang Liu, Curtis R. Brandt, Carol A. Rasmussen & Paul L. Kaufman. (2007) Ocular drug delivery: Molecules, cells, and genes. Canadian Journal of Ophthalmology 42:3, pages 447-454.
Crossref
Ian M. MacDonald, Yves Sauvé & Paul A. Sieving. (2007) Preventing blindness in retinal disease: ciliary neurotrophic factor intraocular implants. Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie 42:3, pages 399-402.
Crossref
Martin Friedlander. (2007) Fibrosis and diseases of the eye. Journal of Clinical Investigation 117:3, pages 576-586.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.