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Review

Cyclodextrins in drug delivery

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Pages 335-351 | Published online: 12 May 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Ahmed AH Abdellatif, Fatma Ahmed, Ahmed M Mohammed, Mansour Alsharidah, Amal Al-Subaiyel, Waad A Samman, Aisha A Alhaddad, Samiah Hamad Al-Mijalli, Mohammed A Amin, Hassan Barakat & Shaaban K Osman. (2023) Recent Advances in the Pharmaceutical and Biomedical Applications of Cyclodextrin-Capped Gold Nanoparticles. International Journal of Nanomedicine 18, pages 3247-3281.
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Ji-Hyun Kang, Ji-Eun Lee, So-Jeong Jeong, Chun-Woong Park, Dong-Wook Kim & Kwon-Yeon Weon. (2022) Design and Optimization of Rivaroxaban-Cyclodextrin-Polymer Triple Complex Formulation with Improved Solubility. Drug Design, Development and Therapy 16, pages 4279-4289.
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Jabson Herber Profiro de Oliveira, Igor Eduardo Silva Arruda, José Izak Ribeiro de Araújo, Luise Lopes Chaves, Mônica Felts de La Rocca Soares & José Lamartine Soares-Sobrinho. (2022) Why do few drug delivery systems to combat neglected tropical diseases reach the market? An analysis from the technology’s stages. Expert Opinion on Therapeutic Patents 32:1, pages 89-114.
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Nazlı Erdoğar, Safiye Akkın, Gamze Varan & Erem Bilensoy. (2021) Erlotinib complexation with randomly methylated β-cyclodextrin improves drug solubility, intestinal permeability, and therapeutic efficacy in non-small cell lung cancer. Pharmaceutical Development and Technology 26:7, pages 797-806.
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Mahima Mathur & Kusum Devi Vemula. (2018) Investigation of different types of nano drug delivery systems of atorvastatin for the treatment of hyperlipidemia. Drug Development and Industrial Pharmacy 44:12, pages 2048-2060.
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Rana Obaidat, Nizar Al-Shar'i, Bassam Tashtoush & Tamara Athamneh. (2018) Enhancement of levodopa stability when complexed with β-cyclodextrin in transdermal patches. Pharmaceutical Development and Technology 23:10, pages 986-997.
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Victoria J. Valerón Bergh, Elin Johannessen, Therese Andersen & Hanne Hjorth Tønnesen. (2018) Evaluation of porphyrin loaded dry alginate foams containing poloxamer 407 and β-cyclodextrin-derivatives intended for wound treatment. Pharmaceutical Development and Technology 23:8, pages 761-770.
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Wipada Samprasit, Prasert Akkaramongkolporn, Ruchadaporn Kaomongkolgit & Praneet Opanasopit. (2018) Cyclodextrin-based oral dissolving films formulation of taste-masked meloxicam. Pharmaceutical Development and Technology 23:5, pages 530-539.
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Vahid Ramezani, Alireza Vatanara, Mohammad Seyedabadi, Mohsen Nabi Meibodi & Hamed Fanaei. (2017) Application of cyclodextrins in antibody microparticles: potentials for antibody protection in spray drying. Drug Development and Industrial Pharmacy 43:7, pages 1103-1111.
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Neha Sharma & Ashish Baldi. (2016) Exploring versatile applications of cyclodextrins: an overview. Drug Delivery 23:3, pages 729-747.
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Tahsin F Kellici, George Liapakis, Andreas G Tzakos & Thomas Mavromoustakos. (2015) Pharmaceutical compositions for antihypertensive treatments: a patent review. Expert Opinion on Therapeutic Patents 25:11, pages 1305-1317.
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GB de Oliveira Makson, Adriana G Guimarães, AS Araújo Adriano, SS Quintans Jullyana, Márcio RV Santos & Lucindo J Quintans-Júnior. (2015) Cyclodextrins: improving the therapeutic response of analgesic drugs: a patent review. Expert Opinion on Therapeutic Patents 25:8, pages 897-907.
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Srinivasa M. Sammeta, Li Wang, Shravan K. Mutyam, Kathleen O’Loughlin, Carol E. Green, Milton H. Werner, Terence Kelly & Gita N. Shankar. (2015) Formulation approaches to improving the delivery of an antiviral drug with activity against seasonal flu. Pharmaceutical Development and Technology 20:2, pages 169-175.
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Mahendra Nath Roy, Palash Chakraborti & Deepak Ekka. (2014) Exploration of interactions between bioactive solutes and vitamin B9 in aqueous medium by physico-chemical contrivances. Molecular Physics 112:17, pages 2215-2226.
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Jun Chen, Wen-Li Lu, Wei Gu, Shan-Shan Lu, Zhi-Peng Chen, Bao-Chang Cai & Xi-Xiong Yang. (2014) Drug-in-cyclodextrin-in-liposomes: a promising delivery system for hydrophobic drugs. Expert Opinion on Drug Delivery 11:4, pages 565-577.
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Amit K. Shah & Christy M. Wyandt. (2013) Factors affecting solubilization of a poorly soluble novel tubulin-binding agent. Pharmaceutical Development and Technology 18:6, pages 1319-1328.
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Alessandro Marinelli & Alessandro Capucci. (2012) Amiodarone (Nexterone) injection for the treatment and prophylaxis of frequently recurring ventricular fibrillation. Expert Opinion on Pharmacotherapy 13:4, pages 573-584.
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Abhishek Singh, Zelalem Ayenew Worku & Guy Van den Mooter. (2011) Oral formulation strategies to improve solubility of poorly water-soluble drugs. Expert Opinion on Drug Delivery 8:10, pages 1361-1378.
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A.L. Laza-Knoerr, R. Gref & P. Couvreur. (2010) Cyclodextrins for drug delivery. Journal of Drug Targeting 18:9, pages 645-656.
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Paul F Souney, Warren D Cooper & Daniel J Cushing. (2010) PM101: intravenous amiodarone formulation changes can improve medication safety. Expert Opinion on Drug Safety 9:2, pages 319-333.
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Yi Shi, William Porter, Thomas Merdan & Luk Chiu Li. (2009) Recent advances in intravenous delivery of poorly water-soluble compounds. Expert Opinion on Drug Delivery 6:12, pages 1261-1282.
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R. Ravichandran. (2009) Nanoparticles in Drug Delivery: Potential Green Nanobiomedicine Applications. International Journal of Green Nanotechnology: Biomedicine 1:2, pages B108-B130.
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Mark Welliver, John McDonough, Nicholas Kalynych & Robert Redfern. (2008) Discovery, development, and clinical application of sugammadex sodium, a selective relaxant binding agent. Drug Design, Development and Therapy 2, pages 49-59.
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Clifford L. Kear, Jing Yang, Donald A. Godwin & Linda A. Felton. (2008) Investigation into the Mechanism by Which Cyclodextrins Influence Transdermal Drug Delivery. Drug Development and Industrial Pharmacy 34:7, pages 692-697.
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Tongalp H Tezel. (2007) Intraocular pharmacotherapy: specificity and safety issues. Expert Review of Ophthalmology 2:5, pages 671-675.
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Alfred Fahr & Xiangli Liu. (2007) Drug delivery strategies for poorly water-soluble drugs. Expert Opinion on Drug Delivery 4:4, pages 403-416.
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Hailiang Chen, Jianqing Gao, Fei Wang & Wenquan Liang. (2007) Preparation, Characterization and Pharmacokinetics of Liposomes-Encapsulated Cyclodextrins Inclusion Complexes for Hydrophobic Drugs. Drug Delivery 14:4, pages 201-208.
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