Advanced search
Publication Cover
Expert Opinion on Drug Delivery Volume 10, 2013 - Issue 10
Submit an article Journal homepage
758
Views
61
CrossRef citations to date
0
Altmetric
Reviews

Strategies for triggered drug release from tumor targeted liposomes

Erik Oude BlenkeUtrecht University, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The [email protected]
,
Enrico MastrobattistaUtrecht University, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The [email protected]
&
Raymond M. SchiffelersUniversity Medical Center Utrecht, Department of Clinical Chemistry & Hematology, Utrecht, The Netherlands
Pages 1399-1410 | Published online: 25 Jun 2013

Citations (61)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Qiang Chen, Chunjing Guo, Zhongxin Liu, Min Cao, Wenxin Wang, Dandan Zhang, Hongxu Geng, Ningning Diao & Daquan Chen. (2023) Multifunctional nanoparticles with anti-inflammatory effect for improving metabolic syndromes. Journal of Drug Targeting 31:3, pages 286-295.
Read now
Sahand Mazloum-Ravasan, Maryam Mohammadi, Elaheh Madadi Hiagh, Alireza Ebrahimi, Joo-Hyun Hong, Hamed Hamishehkar & Ki Hyun Kim. (2022) Nano-liposomal zein hydrolysate for improved apoptotic activity and therapeutic index in lung cancer treatment. Drug Delivery 29:1, pages 1049-1059.
Read now
Atefeh Biabangard, Ahmad Asoodeh, Mahmoud Reza Jaafari & Mohammad Mashreghi. (2022) Study of FA12 peptide-modified PEGylated liposomal doxorubicin (PLD) as an effective ligand to target Muc1 in mice bearing C26 colon carcinoma: in silico, in vitro, and in vivo study. Expert Opinion on Drug Delivery 19:12, pages 1710-1724.
Read now
Yu. A. Tereshkina, T. I. Torkhovskaya, E. G. Tikhonova, L. V. Kostryukova, M. A. Sanzhakov, E. I. Korotkevich, Yu. Yu. Khudoklinova, N. A. Orlova & E. F. Kolesanova. (2022) Nanoliposomes as drug delivery systems: safety concerns. Journal of Drug Targeting 30:3, pages 313-325.
Read now
Cheng Wang, Min Han, Xuerong Liu, Shaoqing Chen, Fuqiang Hu, Jihong Sun & Hong Yuan. (2019) Mitoxantrone-preloaded water-responsive phospholipid-amorphous calcium carbonate hybrid nanoparticles for targeted and effective cancer therapy. International Journal of Nanomedicine 14, pages 1503-1517.
Read now
Bingtao Zhai, Yiying Zeng, Zhaowu Zeng, Nana Zhang, Chenxi Li, Yijun Zeng, Yu You, Shuling Wang, Xiabin Chen, Xinbing Sui & Tian Xie. (2018) Drug delivery systems for elemene, its main active ingredient β-elemene, and its derivatives in cancer therapy. International Journal of Nanomedicine 13, pages 6279-6296.
Read now
Tinghe Yu, Li Luo & Li Wang. (2016) Ultrasound as a cancer chemotherapy sensitizer: the gap between laboratory and bedside. Expert Opinion on Drug Delivery 13:1, pages 37-47.
Read now
Chih-Hsien Chang, Shin-Yi Liu, Chih-Wen Chi, Hsiang-Lin Yu, Tsui-Jung Chang, Tung-Hu Tsai, Te-Wei Lee & Yu-Jen Chen. (2015) External beam radiotherapy synergizes 188Re-liposome against human esophageal cancer xenograft and modulates 188Re-liposome pharmacokinetics. International Journal of Nanomedicine 10, pages 3641-3649.
Read now

Articles from other publishers (53)

Han Liu, Zhiyang Wen, Zihan Liu, Yanfang Yang, Hongliang Wang, Xuejun Xia, Jun Ye & Yuling Liu. (2023) Unlocking the potential of amorphous calcium carbonate: a star ascending in the realm of biomedical application. Acta Pharmaceutica Sinica B.
Crossref
Ekta Pardhi, Rati Yadav, Akash Chaurasiya, Jitender Madan, Santosh Kumar Guru, Shashi Bala Singh & Neelesh Kumar Mehra. (2023) Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies. Life Sciences 325, pages 121771.
Crossref
Zeynab Soosani, Behzad Rezaei, Esmaeil Heydari-Bafrooei & Ali A. Ensafi. (2023) Chemical Sensors Based on Molecularly Imprinted Polymers Can Determine Drug Release Kinetics from Nanocarriers without Filtration, Centrifugation, and Dialysis Steps. ACS Sensors 8:5, pages 1891-1900.
Crossref
Zhuoyan Xie, Junrui Wang, Yuanli Luo, Bin Qiao, Weixi Jiang, Leilei Zhu, Haitao Ran, Zhigang Wang, Wei Zhu, Jianli Ren & Zhiyi Zhou. (2023) Tumor-penetrating nanoplatform with ultrasound “unlocking” for cascade synergistic therapy and visual feedback under hypoxia. Journal of Nanobiotechnology 21:1.
Crossref
Anindita Behera, Santwana Padhi & Amit Kumar Nayak. 2023. Design and Applications of Theranostic Nanomedicines. Design and Applications of Theranostic Nanomedicines 75 108 .
Jian Li, Yanting Gao, Shihe Liu, Jiahui Cai, Qing Zhang, Kun Li, Zhiwei Liu, Ming Shi, Jidong Wang & Hongxia Cui. (2022) Aptamer-functionalized quercetin thermosensitive liposomes for targeting drug delivery and antitumor therapy. Biomedical Materials 17:6, pages 065003.
Crossref
Zhenfeng Shi, Jifang Liu, Lei Tian, Jingyi Li, Yue Gao, Yue Xing, Wenjing Yan, Chenyu Hua, Xiaolin Xie, Chang Liu & Chengyuan Liang. (2022) Insights into stimuli-responsive diselenide bonds utilized in drug delivery systems for cancer therapy. Biomedicine & Pharmacotherapy 155, pages 113707.
Crossref
Jinchao Lou, Megan L. Qualls, Macy M. Hudson, Dillon P. McBee, Joshua A. Baccile & Michael D. Best. (2022) Reactive Oxygen Species (ROS) Activated Liposomal Cell Delivery using a Boronate‐Caged Guanidine Lipid. Chemistry – A European Journal 28:46.
Crossref
Beatriz D. Cardoso, Vanessa F. Cardoso, Senetxu Lanceros-Méndez & Elisabete M. S. Castanheira. (2022) Solid Magnetoliposomes as Multi-Stimuli-Responsive Systems for Controlled Release of Doxorubicin: Assessment of Lipid Formulations. Biomedicines 10:5, pages 1207.
Crossref
Megan L. Qualls, Ruhani Sagar, Jinchao Lou & Michael D. Best. (2021) Demolish and Rebuild: Controlling Lipid Self-Assembly toward Triggered Release and Artificial Cells. The Journal of Physical Chemistry B 125:47, pages 12918-12933.
Crossref
Danli Sheng, Liming Deng, Pan Li, Zhigang Wang & Qunxia Zhang. (2021) Perfluorocarbon Nanodroplets with Deep Tumor Penetration and Controlled Drug Delivery for Ultrasound/Fluorescence Imaging Guided Breast Cancer Therapy. ACS Biomaterials Science & Engineering 7:2, pages 605-616.
Crossref
Xin Zhao, Yun Ye, Shuyu Ge, Pingping Sun & Ping Yu. (2020) Cellular and Molecular Targeted Drug Delivery in Central Nervous System Cancers: Advances in Targeting Strategies. Current Topics in Medicinal Chemistry 20:30, pages 2762-2776.
Crossref
Amalia Ruiz, Guanglong Ma, Jani Seitsonen, Sara G.T. Pereira, Janne Ruokolainen & Wafa T. Al-Jamal. (2020) Encapsulated doxorubicin crystals influence lysolipid temperature-sensitive liposomes release and therapeutic efficacy in vitro and in vivo. Journal of Controlled Release 328, pages 665-678.
Crossref
Chao Hong, Jianming Liang, Jiaxuan Xia, Ying Zhu, Yizhen Guo, Anni Wang, Chunyi Lu, Hongwei Ren, Chen Chen, Shiyi Li, Dan Wang, Huaxing Zhan & Jianxin Wang. (2020) One Stone Four Birds: A Novel Liposomal Delivery System Multi-functionalized with Ginsenoside Rh2 for Tumor Targeting Therapy. Nano-Micro Letters 12:1.
Crossref
Mixiao Tan, Yuli Chen, Yuan Guo, Chao Yang, Mingzhu Liu, Dan Guo, Zhigang Wang, Yang Cao & Haitao Ran. (2020) A low-intensity focused ultrasound-assisted nanocomposite for advanced triple cancer therapy: local chemotherapy, therapeutic extracellular vesicles and combined immunotherapy. Biomaterials Science 8:23, pages 6703-6717.
Crossref
Jinchao Lou & Michael D. Best. (2020) Reactive Oxygen Species-Responsive Liposomes via Boronate-Caged Phosphatidylethanolamine. Bioconjugate Chemistry 31:9, pages 2220-2230.
Crossref
Jing Zhang, Xiang Li & Leaf Huang. (2020) Anticancer activities of phytoconstituents and their liposomal targeting strategies against tumor cells and the microenvironment. Advanced Drug Delivery Reviews 154-155, pages 245-273.
Crossref
Huanan Li, Qianyan Li, Wei Hou, Jingni Zhang, Chenhao Yu, Deping Zeng, Gang Liu & Faqi Li. (2019) Enzyme-Catalytic Self-Triggered Release of Drugs from a Nanosystem for Efficient Delivery to Nuclei of Tumor Cells. ACS Applied Materials & Interfaces 11:46, pages 43581-43587.
Crossref
Hongshu Bi, Jianxiu Xue, Hong Jiang, Shan Gao, Dongjuan Yang, Yan Fang & Kai Shi. (2019) Current developments in drug delivery with thermosensitive liposomes. Asian Journal of Pharmaceutical Sciences 14:4, pages 365-379.
Crossref
Anand Lopez & Juewen Liu. (2018) DNA Oligonucleotide-Functionalized Liposomes: Bioconjugate Chemistry, Biointerfaces, and Applications. Langmuir 34:49, pages 15000-15013.
Crossref
Maria B.C. de Matos, Nataliia Beztsinna, Christoph Heyder, Marcel H.A.M. Fens, Enrico Mastrobattista, Raymond M. Schiffelers, Gero Leneweit & Robbert J. Kok. (2018) Thermosensitive liposomes for triggered release of cytotoxic proteins. European Journal of Pharmaceutics and Biopharmaceutics 132, pages 211-221.
Crossref
Susan Hua, Maria B. C. de Matos, Josbert M. Metselaar & Gert Storm. (2018) Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization. Frontiers in Pharmacology 9.
Crossref
Cheng Wang, Shaoqing Chen, Yunxin Wang, Xuerong Liu, Fuqiang Hu, Jihong Sun & Hong Yuan. (2018) Lipase‐Triggered Water‐Responsive “Pandora's Box” for Cancer Therapy: Toward Induced Neighboring Effect and Enhanced Drug Penetration. Advanced Materials 30:14.
Crossref
Chiara Lambruschini, Silvia Villa, Luca Banfi, Fabio Canepa, Fabio Morana, Annalisa Relini, Paola Riani, Renata Riva & Fulvio Silvetti. (2018) Enzymatically promoted release of organic molecules linked to magnetic nanoparticles. Beilstein Journal of Nanotechnology 9, pages 986-999.
Crossref
B. Børresen, A. E. Hansen, A. Kjaer, T. L. Andresen & A. T. Kristensen. (2018) Liposome-encapsulated chemotherapy: Current evidence for its use in companion animals. Veterinary and Comparative Oncology 16:1, pages E1-E15.
Crossref
Yuxin Guo, Yang Zhang, Jinyuan Ma, Qi Li, Yang Li, Xinyi Zhou, Dan Zhao, Hua Song, Qing Chen & Xuan Zhu. (2018) Light/magnetic hyperthermia triggered drug released from multi-functional thermo-sensitive magnetoliposomes for precise cancer synergetic theranostics. Journal of Controlled Release 272, pages 145-158.
Crossref
Nily Dan. 2018. Design and Development of New Nanocarriers. Design and Development of New Nanocarriers 1 55 .
Tatsuaki Tagami & Tetsuya Ozeki. (2017) Recent Trends in Clinical Trials Related to Carrier-Based Drugs. Journal of Pharmaceutical Sciences 106:9, pages 2219-2226.
Crossref
Houman Pourhassan, Gael Clergeaud, Anders E. Hansen, Ragnhild G. Østrem, Frederikke P. Fliedner, Fredrik Melander, Ole L. Nielsen, Ciara K. O'Sullivan, Andreas Kjær & Thomas L. Andresen. (2017) Revisiting the use of sPLA 2 -sensitive liposomes in cancer therapy. Journal of Controlled Release 261, pages 163-173.
Crossref
Kevin Plourde, Rabeb Mouna Derbali, Arnaud Desrosiers, Céline Dubath, Alexis Vallée-Bélisle & Jeanne Leblond. (2017) Aptamer-based liposomes improve specific drug loading and release. Journal of Controlled Release 251, pages 82-91.
Crossref
Qihang Sun, Zhuxian Zhou, Nasha Qiu & Youqing Shen. (2017) Rational Design of Cancer Nanomedicine: Nanoproperty Integration and Synchronization. Advanced Materials 29:14.
Crossref
E. Oude Blenke, M. Sleszynska, M. J. W. Evers, G. Storm, N. I. Martin & E. Mastrobattista. (2017) Strategies for the Activation and Release of the Membranolytic Peptide Melittin from Liposomes Using Endosomal pH as a Trigger. Bioconjugate Chemistry 28:2, pages 574-582.
Crossref
Shin Mizukami, Masayoshi Kashibe, Kengo Matsumoto, Yuichiro Hori & Kazuya Kikuchi. (2017) Enzyme-triggered compound release using functionalized antimicrobial peptide derivatives. Chemical Science 8:4, pages 3047-3053.
Crossref
Yunlu Dai, Can Xu, Xiaolian Sun & Xiaoyuan Chen. (2017) Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment. Chemical Society Reviews 46:12, pages 3830-3852.
Crossref
Nily Dan. 2017. Nanostructures for Drug Delivery. Nanostructures for Drug Delivery 63 105 .
Dandan Luo, Kevin A. Carter, Dyego Miranda & Jonathan F. Lovell. (2017) Chemophototherapy: An Emerging Treatment Option for Solid Tumors. Advanced Science 4:1, pages 1600106.
Crossref
Ritu Goyal, Lauren K. Macri, Hilton M. Kaplan & Joachim Kohn. (2016) Nanoparticles and nanofibers for topical drug delivery. Journal of Controlled Release 240, pages 77-92.
Crossref
Zibiao Li, Enyi Ye, David, Rajamani Lakshminarayanan & Xian Jun Loh. (2016) Recent Advances of Using Hybrid Nanocarriers in Remotely Controlled Therapeutic Delivery. Small 12:35, pages 4782-4806.
Crossref
Andrey V. Sybachin, Olga V. Zaborova, Kristina M. Imelbaeva, Vyacheslav V. Samoshin, Vasily A. Migulin, Felix A. Plamper & Alexander A. Yaroslavov. (2016) Effects of the electrostatic complexation between anionic pH-sensitive liposomes and star-shaped polycations on the release of the liposomal content. Mendeleev Communications 26:4, pages 276-278.
Crossref
S. L. Hopkins, B. Siewert, S. H. C. Askes, P. Veldhuizen, R. Zwier, Michal Heger & Sylvestre Bonnet. (2016) An in vitro cell irradiation protocol for testing photopharmaceuticals and the effect of blue, green, and red light on human cancer cell lines. Photochemical & Photobiological Sciences 15:5, pages 644-653.
Crossref
Cyril Lorenzato, Chris Oerlemans, Merel van Elk, Willie J. C. Geerts, Baudouin Denis de Senneville, Chrit Moonen & Clemens Bos. (2016) MRI monitoring of nanocarrier accumulation and release using Gadolinium-SPIO co-labelled thermosensitive liposomes. Contrast Media & Molecular Imaging 11:3, pages 184-194.
Crossref
Kayla Miller, Suraj Dixit, Amy-Lee Bredlau, Alfred Moore, Emilie McKinnon & Ann-Marie Broome. (2016) Delivery of a drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers. Nanomedicine 11:6, pages 581-595.
Crossref
Jing Li, Xuling Wang, Ting Zhang, Chunling Wang, Zhenjun Huang, Xiang Luo & Yihui Deng. (2015) A review on phospholipids and their main applications in drug delivery systems. Asian Journal of Pharmaceutical Sciences 10:2, pages 81-98.
Crossref
Ji Liu, Christophe Detrembleur, Stéphane Mornet, Christine Jérôme & Etienne Duguet. (2015) Design of hybrid nanovehicles for remotely triggered drug release: an overview. Journal of Materials Chemistry B 3:30, pages 6117-6147.
Crossref
Alexander A. Yaroslavov, Andrey V. Sybachin, Olga V. Zaborova, Vasiliy A. Migulin, Vyacheslav V. Samoshin, Matthias Ballauff, Ellina Kesselman, Judith Schmidt, Yeshayahu Talmon & Fredric M. Menger. (2015) Capacious and programmable multi-liposomal carriers. Nanoscale 7:5, pages 1635-1641.
Crossref
Mathias Viard & Anu Puri. 2015. 1 41 .
Harmesh Singh Aojula. 2015. Handbook of Vascular Biology Techniques. Handbook of Vascular Biology Techniques 325 341 .
Dorota Matyszewska. (2014) Drug delivery systems in the transport of doxorubicin. Surface Innovations 2:4, pages 201-210.
Crossref
XIAO-JIAN HAN, YONG-FANG WEI, YU-YING WAN, LI-PING JIANG, JIAN-FENG ZHANG & HONG-BO XIN. (2014) Development of a novel liposomal nanodelivery system for bioluminescence imaging and targeted drug delivery in ErbB2-overexpressing metastatic ovarian carcinoma. International Journal of Molecular Medicine 34:5, pages 1225-1232.
Crossref
Trinh Nguyen, Amy Tekrony, Kristin Yaehne & David T Cramb. (2014) Designing a better theranostic nanocarrier for cancer applications. Nanomedicine 9:15, pages 2371-2386.
Crossref
Sihem Ait-Oudhia, Donald Mager & Robert Straubinger. (2014) Application of Pharmacokinetic and Pharmacodynamic Analysis to the Development of Liposomal Formulations for Oncology. Pharmaceutics 6:1, pages 137-174.
Crossref
Peter Hinow & Ami E. Radunskaya. 2014. Mathematical Models of Tumor-Immune System Dynamics. Mathematical Models of Tumor-Immune System Dynamics 109 123 .
Anu Puri. (2013) Phototriggerable Liposomes: Current Research and Future Perspectives. Pharmaceutics 6:1, pages 1-25.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.