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The role of microneedles for drug and vaccine delivery

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Anusha V. M.Sarasija Suresh, Avichal Kumar, Paranjyothy K.Reena N. M.Srinath Rangappa, S. Narasimha Murthy & Shivakumar H.N.. (2023) Overcoming challenges in dermal and transdermal delivery of herbal therapeutics with polymeric microneedles. Journal of Biomaterials Science, Polymer Edition 0:0, pages 1-33.
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Saki Yoneda, Tetsuo Torisu & Susumu Uchiyama. (2021) Development of syringes and vials for delivery of biologics: current challenges and innovative solutions. Expert Opinion on Drug Delivery 18:4, pages 459-470.
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Aoife Maria Rodgers, Ana Sara Cordeiro, Adrien Kissenpfennig & Ryan F Donnelly. (2018) Microneedle arrays for vaccine delivery: the possibilities, challenges and use of nanoparticles as a combinatorial approach for enhanced vaccine immunogenicity. Expert Opinion on Drug Delivery 15:9, pages 851-867.
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Jeong Woo Lee & Mark R. Prausnitz. (2018) Drug delivery using microneedle patches: not just for skin. Expert Opinion on Drug Delivery 15:6, pages 541-543.
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Thuy Trang Nguyen & Jung Hwan Park. (2018) Human studies with microneedles for evaluation of their efficacy and safety. Expert Opinion on Drug Delivery 15:3, pages 235-245.
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Raghu Raj Thakur Singh, Ismaiel Tekko, Kathryn McAvoy, Hannah McMillan, David Jones & Ryan F. Donnelly. (2017) Minimally invasive microneedles for ocular drug delivery. Expert Opinion on Drug Delivery 14:4, pages 525-537.
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Chao Wang, Yanqi Ye & Zhen Gu. (2017) Local delivery of checkpoints antibodies. Human Vaccines & Immunotherapeutics 13:1, pages 245-248.
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Adam C. Watkinson, Mary-Carmel Kearney, Helen L. Quinn, Aaron J. Courtenay & Ryan F. Donnelly. (2016) Future of the transdermal drug delivery market – have we barely touched the surface?. Expert Opinion on Drug Delivery 13:4, pages 523-532.
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Ibrahim A. Aljuffali, Yin-Ku Lin & Jia-You Fang. (2016) Noninvasive approach for enhancing small interfering RNA delivery percutaneously. Expert Opinion on Drug Delivery 13:2, pages 265-280.
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N. Sanoj Rejinold, Ju-Hyung Shin, Hae Yong Seok & Yeu-Chun Kim. (2016) Biomedical applications of microneedles in therapeutics: recent advancements and implications in drug delivery. Expert Opinion on Drug Delivery 13:1, pages 109-131.
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Articles from other publishers (115)

Dong Ha Lee, Sunyoung Lim, Sung Soo Kwak & Joohee Kim. (2023) Advancements in Skin‐Mediated Drug Delivery: Mechanisms, Techniques, and Applications. Advanced Healthcare Materials.
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Yiming Xia, Shunli Fu, Qingping Ma, Yongjun Liu & Na Zhang. (2023) Application of Nano-Delivery Systems in Lymph Nodes for Tumor Immunotherapy. Nano-Micro Letters 15:1.
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Shikha Mahant, Abhishek Kumar Sharma, Himanshu Gandhi, Ridhima Wadhwa, Kamal Dua & Deepak N. Kapoor. (2023) Emerging Trends and Potential Prospects in Vaginal Drug Delivery. Current Drug Delivery 20:6, pages 730-751.
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AMAN TIWARI, SHUBHAM SHARMA, PRAKASH KUMAR SONI & SURESH KUMAR PASWAN. (2023) FABRICATION AND DEVELOPMENT OF DISSOLVING MICRONEEDLE PATCH OF BUTORPHANOL TARTRATE. International Journal of Applied Pharmaceutics, pages 261-271.
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Martina Iapichino, Howard Maibach & Boris Stoeber. (2023) Quantification methods comparing in vitro and in vivo percutaneous permeation by microneedles and passive diffusion. International Journal of Pharmaceutics 638, pages 122885.
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Irina Iachina, André H. Eriksson, Malene Bertelsen, Karsten Petersson, Jörgen Jansson, Pernille Kemp, Karen M. Engell, Jonathan R. Brewer & Kim T. Nielsen. (2023) Dissolvable microneedles for transdermal drug delivery showing skin penetration and modified drug release. European Journal of Pharmaceutical Sciences 182, pages 106371.
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Seung‐Hwan Joo, Jaehyun Kim, Juhyeong Hong, Shayan Fakhraei Lahiji & Yong‐Hee Kim. (2023) Dissolvable Self‐Locking Microneedle Patches Integrated with Immunomodulators for Cancer Immunotherapy. Advanced Materials 35:10.
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Soraya Babaie, Arezou Taghvimi, Joo-Hyun Hong, Hamed Hamishehkar, Seongpil An & Ki Hyun Kim. (2022) Recent advances in pain management based on nanoparticle technologies. Journal of Nanobiotechnology 20:1.
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Yao Zhang, Youyu Sheng, Yibin Zeng, Ruiming Hu, Jun Zhao, Wuqing Wang & Qinping Yang. (2022) Randomized trial of microneedling combined with 2% minoxidil topical solution for the treatment of female pattern hair loss in a Chinese population. Journal of Cosmetic Dermatology 21:12, pages 6985-6991.
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Nimra Tariq, Muhammad Waseem Ashraf & Shahzadi Tayyaba. (2021) A Review on Solid Microneedles for Biomedical Applications. Journal of Pharmaceutical Innovation 17:4, pages 1464-1483.
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Jin Ah Kim, Soo Chan Park, Seung-Jun Lee & Jin-Chul Kim. (2022) Cellulose nanofiber-reinforced dissolving microneedles for transdermal delivery of a water-soluble compound. Cellulose 29:18, pages 9881-9897.
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Yuchen Wang & Guan Jiang. (2022) Advances in the Novel Nanotechnology for Targeted Tumor Therapy by Transdermal Drug Delivery. Anti-Cancer Agents in Medicinal Chemistry 22:15, pages 2708-2714.
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Yali Lin, Ruomei Shao, Tong Xiao & Shuqing Sun. (2022) Promotion of Hair Regrowth by Transdermal Dissolvable Microneedles Loaded with Rapamycin and Epigallocatechin Gallate Nanoparticles. Pharmaceutics 14:7, pages 1404.
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Nimra Tariq, Muhammad Waseem Ashraf, Shahzadi Tayyaba, Agustín L. Herrera-May & Enrique Delgado-Alvarado. (2022) Numerical Simulation, Analysis, and Fabrication of MEMS-Based Solid Ag and Cu Microneedles for Biomedical Applications. Mathematical Problems in Engineering 2022, pages 1-19.
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Abdulla Al Mamun & Feng Zhao. (2022) In-Plane Si Microneedles: Fabrication, Characterization, Modeling and Applications. Micromachines 13:5, pages 657.
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Deepanjan Datta, Girdhari Roy, Prashant Garg & Venkata Vamsi Krishna Venuganti. (2022) Ocular delivery of cyclosporine A using dissolvable microneedle contact lens. Journal of Drug Delivery Science and Technology 70, pages 103211.
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Xiaoxuan Jin, Xiangdong Zhang, Yibao Li, Mimi Xu, Yao Yao, Zongjian Wu, Yunfan He, Jianhua Gao & Bin Li. (2022) Long-acting microneedle patch loaded with adipose collagen fragment for preventing the skin photoaging in mice. Biomaterials Advances 135, pages 212744.
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Haojie Wei, Shuang Liu, Zexin Tong, Tiantian Chen, Ming Yang, Yuandong Guo, Huixuan Sun, Yao Wu, Yingying Chu & Lihong Fan. (2022) Hydrogel-based microneedles of chitosan derivatives for drug delivery. Reactive and Functional Polymers 172, pages 105200.
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Xiaoyan Lu, Yiying Sun, Meishan Han, Daoyuan Chen, Aiping Wang & Kaoxiang Sun. (2022) Silk fibroin double-layer microneedles for the encapsulation and controlled release of triptorelin. International Journal of Pharmaceutics 613, pages 121433.
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Xiao Peng Zhang, Bao Li Zhang, Bo Zhi Chen, Ze Qiang Zhao, Wen Min Fei, Yong Cui & Xin Dong Guo. (2021) Dissolving microneedle rollers for rapid transdermal drug delivery. Drug Delivery and Translational Research 12:2, pages 459-471.
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Minki Jin, Woo-Jin Jeon, Haesoo Lee, Minwoo Jung, Ha-Eun Kim, Hyelim Yoo, Jong-Hee Won, Jong Chan Kim, Jung-Hwan Park, Mi-Jin Yang, Hong-Ki Lee & Cheong-Weon Cho. (2021) Preparation and evaluation of rapid disintegrating formulation from coated microneedle. Drug Delivery and Translational Research 12:2, pages 415-425.
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Lalitkumar K. Vora, Kurtis Moffatt & Ryan F. Donnelly. 2022. Long-Acting Drug Delivery Systems. Long-Acting Drug Delivery Systems 249 287 .
Apoorva Panda, V. Anusha Matadh, Sarasija Suresh, H. N. Shivakumar & S. Narasimha Murthy. (2021) Non-dermal applications of microneedle drug delivery systems. Drug Delivery and Translational Research 12:1, pages 67-78.
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Jingbo Yang, Haoxiang Zhang, Tianli Hu, Chenjie Xu, Lelun Jiang, Yu Shrike Zhang & Maobin Xie. (2021) Recent advances of microneedles used towards stimuli-responsive drug delivery, disease theranostics, and bioinspired applications. Chemical Engineering Journal 426, pages 130561.
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Ciro Chiappini, Yaping Chen, Stella Aslanoglou, Anna Mariano, Valentina Mollo, Huanwen Mu, Enrica De Rosa, Gen He, Ennio Tasciotti, Xi Xie, Francesca Santoro, Wenting Zhao, Nicolas H. Voelcker & Roey Elnathan. (2021) Tutorial: using nanoneedles for intracellular delivery. Nature Protocols 16:10, pages 4539-4563.
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G. Cummins. (2021) Smart pills for gastrointestinal diagnostics and therapy. Advanced Drug Delivery Reviews 177, pages 113931.
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Abhay TharmattDanish MalhotraHamayal SharmaNeena Bedi. (2021) Pharmaceutical Perspective in Wearable Drug Delivery Systems. ASSAY and Drug Development Technologies 19:6, pages 386-401.
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Srividya Gorantla, Neha Dabholkar, Sudhanshu Sharma, Vamshi Krishna Rapalli, Amit Alexander & Gautam Singhvi. (2021) Chitosan-based microneedles as a potential platform for drug delivery through the skin: Trends and regulatory aspects. International Journal of Biological Macromolecules 184, pages 438-453.
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Satish Rojekar, Lalitkumar K. Vora, Ismaiel A. Tekko, Fabiana Volpe-Zanutto, Helen O. McCarthy, Pradeep R. Vavia & Ryan F .Donnelly. (2021) Etravirine-loaded dissolving microneedle arrays for long-acting delivery. European Journal of Pharmaceutics and Biopharmaceutics 165, pages 41-51.
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Vo Thi Nhat Linh, Sang-Gu Yim, ChaeWon Mun, Jun-Yeong Yang, Seunghun Lee, Yeon Woo Yoo, Dong Kyung Sung, Yong-Ill Lee, Dong-Ho Kim, Sung-Gyu Park, Seung Yun Yang & Ho Sang Jung. (2021) Bioinspired plasmonic nanoflower-decorated microneedle for label-free intradermal sensing. Applied Surface Science 551, pages 149411.
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Alejandro J. Paredes, Inken K. Ramöller, Peter E. McKenna, Marco T.A. Abbate, Fabiana Volpe-Zanutto, Lalitkumar K. Vora, Maggie Kilbourne-Brook, Courtney Jarrahian, Kurtis Moffatt, Chunyang Zhang, Ismaiel A. Tekko & Ryan F. Donnelly. (2021) Microarray patches: Breaking down the barriers to contraceptive care and HIV prevention for women across the globe. Advanced Drug Delivery Reviews 173, pages 331-348.
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C. M. de Korne, B. M. F. Winkel, M. N. van Oosterom, S. Chevalley-Maurel, H. M. Houwing, J. C. Sijtsma, S. Azargoshasb, E. Baalbergen, B. M. D. Franke-Fayard, F. W. B. van Leeuwen & M. Roestenberg. (2021) Clustering and Erratic Movement Patterns of Syringe-Injected versus Mosquito-Inoculated Malaria Sporozoites Underlie Decreased Infectivity. mSphere 6:2.
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Jesse O’Shea, Mark R. Prausnitz & Nadine Rouphael. (2021) Dissolvable Microneedle Patches to Enable Increased Access to Vaccines against SARS-CoV-2 and Future Pandemic Outbreaks. Vaccines 9:4, pages 320.
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Emrullah Korkmaz, Stephen C. Balmert, Tina L. Sumpter, Cara Donahue Carey, Geza Erdos & Louis D. FaloJrJr. (2021) Microarray patches enable the development of skin-targeted vaccines against COVID-19. Advanced Drug Delivery Reviews 171, pages 164-186.
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Faris Soloman Almadi & Saad I Mallah. (2021) STAR particles in context: a novel contender in the search for optimized drug-delivery systems. Therapeutic Delivery 12:3, pages 175-181.
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Hamed Amani, Mohammad-Ali Shahbazi, Carmine D'Amico, Flavia Fontana, Samin Abbaszadeh & Hélder A. Santos. (2021) Microneedles for painless transdermal immunotherapeutic applications. Journal of Controlled Release 330, pages 185-217.
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Lalit K. Vora, Kurtis Moffatt, Ismaiel A. Tekko, Alejandro J. Paredes, Fabiana Volpe-Zanutto, Deepakkumar Mishra, Ke Peng, Raghu Raj Singh Thakur & Ryan F. Donnelly. (2021) Microneedle array systems for long-acting drug delivery. European Journal of Pharmaceutics and Biopharmaceutics 159, pages 44-76.
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Ashana Puri, Hiep X Nguyen, Akeemat O Tijani & Ajay K Banga. (2021) Characterization of microneedles and microchannels for enhanced transdermal drug delivery. Therapeutic Delivery 12:1, pages 77-103.
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Dongdong Li, Doudou Hu, Hongxia Xu, Hirak K. Patra, Xiangrui Liu, Zhuxian Zhou, Jianbin Tang, Nigel Slater & Youqing Shen. (2021) Progress and perspective of microneedle system for anti-cancer drug delivery. Biomaterials 264, pages 120410.
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Emma McAlister, Melissa Kirkby & Ryan F. Donnelly. 2021. Microfluidic Devices for Biomedical Applications. Microfluidic Devices for Biomedical Applications 225 260 .
Sangwook Chu, Nikhil Uplekar, Sanwei Liu & Reza Ghodssi. (2020) Complementary Capillary System Integrated Microneedles for Autonomously Localized Therapeutics Loading. Journal of Microelectromechanical Systems 29:5, pages 912-917.
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Rigved Nagarkar, Mahima Singh, Hiep X. Nguyen & Sriramakamal Jonnalagadda. (2020) A review of recent advances in microneedle technology for transdermal drug delivery. Journal of Drug Delivery Science and Technology 59, pages 101923.
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Defu Zhi, Ting Yang, Justin O'Hagan, Shubiao Zhang & Ryan F. Donnelly. (2020) Photothermal therapy. Journal of Controlled Release 325, pages 52-71.
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Khater Ahmed Saeed AL-Japairai, Syed Mahmood, Samah Hamed Almurisi, Jayarama Reddy Venugopal, Ayah Rebhi Hilles, Motia Azmana & Subashini Raman. (2020) Current trends in polymer microneedle for transdermal drug delivery. International Journal of Pharmaceutics 587, pages 119673.
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Boris Stoeber, Raja K Sivamani & Howard I. MaibachJanet Tamada. 2020. Microneedling in Clinical Practice. Microneedling in Clinical Practice 109 118 .
Hongpeng Shi, Tong Xue, Yang YangChenyu Jiang, Shixing Huang, Qi YangDong LeiZhengwei YouTuo JinFei Wu, Qiang Zhao & Xiaofeng Ye. (2020) Microneedle-mediated gene delivery for the treatment of ischemic myocardial disease. Science Advances 6:25.
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Young-Guk Na, Minki Kim, Mingu Han, Hyun Wook Huh, Ji-Seok Kim, Jong Chan Kim, Jung-Hwan Park, Hong-Ki Lee & Cheong-Weon Cho. (2020) Characterization of Hepatitis B Surface Antigen Loaded Polylactic Acid-Based Microneedle and Its Dermal Safety Profile. Pharmaceutics 12:6, pages 531.
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Stephen A. Kelly, Aoife M. Rodgers, Séamus C. O’Brien, Ryan F. Donnelly & Brendan F. Gilmore. (2020) Gut Check Time: Antibiotic Delivery Strategies to Reduce Antimicrobial Resistance. Trends in Biotechnology 38:4, pages 447-462.
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Muamer Dervisevic, Maria Alba, Beatriz Prieto-Simon & Nicolas H. Voelcker. (2020) Skin in the diagnostics game: Wearable biosensor nano- and microsystems for medical diagnostics. Nano Today 30, pages 100828.
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Merima Sirbubalo, Mirela Camović, Amina Tucak, Kenan Muhamedagić, Ognjenka Rahić, Jasmina Hadžiabdić, Lamija Hindija, Ahmet Čekić, Marija Glavas-Dodov & Edina Vranić. (2020) Fabrication of 3D-printed PLA microneedles as physical permeation enhancers in transdermal delivery. Macedonian Pharmaceutical Bulletin 66:03, pages 147-148.
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Pragya Misra & Shailza Singh. 2020. Systems and Synthetic Immunology. Systems and Synthetic Immunology 1 52 .
Eman M. Migdadi & Ryan F. Donnelly. 2019. Imaging Technologies and Transdermal Delivery in Skin Disorders. Imaging Technologies and Transdermal Delivery in Skin Disorders 223 270 .
Mary-Carmel Kearney, Peter E. McKenna, Helen L. Quinn, Aaron J. Courtenay, Eneko Larrañeta & Ryan F. Donnelly. (2019) Design and Development of Liquid Drug Reservoirs for Microneedle Delivery of Poorly Soluble Drug Molecules. Pharmaceutics 11:11, pages 605.
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Srijanaki Paravastu Pattarabhiran, Anjana Saju, Kanchan Rajendra Sonawane, Raghuraman Manimaran, Shubhmita Bhatnagar, Girdhari Roy, Radha Balkrishna Kulkarni & Venkata Vamsi Krishna Venuganti. (2019) Dissolvable Microneedle-Mediated Transcutaneous Delivery of Tetanus Toxoid Elicits Effective Immune Response. AAPS PharmSciTech 20:7.
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Rohan S.J. Ingrole & Harvinder Singh Gill. (2019) Microneedle Coating Methods: A Review with a Perspective. Journal of Pharmacology and Experimental Therapeutics 370:3, pages 555-569.
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Iakovos Xenikakis, Manolis Tzimtzimis, Konstantinos Tsongas, Dimitrios Andreadis, Euterpi Demiri, Dimitrios Tzetzis & Dimitrios G. Fatouros. (2019) Fabrication and finite element analysis of stereolithographic 3D printed microneedles for transdermal delivery of model dyes across human skin in vitro. European Journal of Pharmaceutical Sciences 137, pages 104976.
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Jessica C. Joyce, Hila E. Sella, Heather Jost, Matthew J. Mistilis, E. Stein Esser, Pallab Pradhan, Randall Toy, Marcus L. Collins, Paul A. Rota, Krishnendu Roy, Ioanna Skountzou, Richard W. Compans, M. Steven Oberste, William C. Weldon, James J. Norman & Mark R. Prausnitz. (2019) Extended delivery of vaccines to the skin improves immune responses. Journal of Controlled Release 304, pages 135-145.
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Heather A.E. Benson, Jeffrey E. Grice, Yousuf Mohammed, Sarika Namjoshi & Michael S. Roberts. (2019) Topical and Transdermal Drug Delivery: From Simple Potions to Smart Technologies. Current Drug Delivery 16:5, pages 444-460.
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Catherine Hegarty, Aaron McConville, Ruairi J. McGlynn, Davide Mariotti & James Davis. (2019) Design of composite microneedle sensor systems for the measurement of transdermal pH. Materials Chemistry and Physics 227, pages 340-346.
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Ya Gao, Mengmeng Hou, Ruihao Yang, Lei Zhang, Zhigang Xu, Yuejun Kang & Peng Xue. (2019) Highly Porous Silk Fibroin Scaffold Packed in PEGDA/Sucrose Microneedles for Controllable Transdermal Drug Delivery. Biomacromolecules 20:3, pages 1334-1345.
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Tan Tang, Tujun Weng, Hongxing Jia, Sida Luo, Ye Xu, Liuhe Li & Peipei Zhang. (2019) Harnessing the layer-by-layer assembly technique to design biomaterials vaccines for immune modulation in translational applications. Biomaterials Science 7:3, pages 715-732.
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Seok Park, Min Kim, Seung-Ki Baek, Jung-Hwan Park & Seong-O Choi. (2019) Spray-Formed Layered Polymer Microneedles for Controlled Biphasic Drug Delivery. Polymers 11:2, pages 369.
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Amin GhavamiNejad, Brian Lu & Xiao Yu Wu. 2019. Biomimetic Nanoengineered Materials for Advanced Drug Delivery. Biomimetic Nanoengineered Materials for Advanced Drug Delivery 37 52 .
Monica Sharma. 2019. Applications of Targeted Nano Drugs and Delivery Systems. Applications of Targeted Nano Drugs and Delivery Systems 499 550 .
Rachel L. Creighton & Kim A. Woodrow. (2018) Microneedle‐Mediated Vaccine Delivery to the Oral Mucosa. Advanced Healthcare Materials, pages 1801180.
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Maelíosa T.C. Mc Crudden, Eneko Larrañeta, Annie Clark, Courtney Jarrahian, Annie Rein-Weston, Sophie Lachau-Durand, Nico Niemeijer, Peter Williams, Clement Haeck, Helen O. McCarthy, Darin Zehrung & Ryan F. Donnelly. (2018) Design, formulation and evaluation of novel dissolving microarray patches containing a long-acting rilpivirine nanosuspension. Journal of Controlled Release 292, pages 119-129.
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Ya Gao, Mengmeng Hou, Ruihao Yang, Lei Zhang, Zhigang Xu, Yuejun Kang & Peng Xue. (2018) PEGDA/PVP Microneedles with Tailorable Matrix Constitutions for Controllable Transdermal Drug Delivery. Macromolecular Materials and Engineering 303:12, pages 1800233.
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Nak Won Kim, Sun-Young Kim, Jung Eun Lee, Yue Yin, Jong Han Lee, Su Yeon Lim, E Seul Kim, Huu Thuy Trang Duong, Hong Kee Kim, Sohyun Kim, Jung-Eun Kim, Doo Sung Lee, Jaeyoon Kim, Min Sang Lee, Yong Taik Lim & Ji Hoon Jeong. (2018) Enhanced Cancer Vaccination by In Situ Nanomicelle-Generating Dissolving Microneedles . ACS Nano 12:10, pages 9702-9713.
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Monica B. Perez Cuevas, Maja Kodani, Youkyung Choi, Jessica Joyce, Siobhan M. O'Connor, Saleem Kamili & Mark R. Prausnitz. (2018) Hepatitis B vaccination using a dissolvable microneedle patch is immunogenic in mice and rhesus macaques. Bioengineering & Translational Medicine 3:3, pages 186-196.
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Boonnada Pamornpathomkul, Tanasait Ngawhirunpat, Ismaiel A. Tekko, Lalitkumar Vora, Helen O. McCarthy & Ryan F. Donnelly. (2018) Dissolving polymeric microneedle arrays for enhanced site-specific acyclovir delivery. European Journal of Pharmaceutical Sciences 121, pages 200-209.
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Mary-Carmel Kearney, Sarah Brown, Iman Hamdan & Ryan F. Donnelly. 2018. Microneedles for Drug and Vaccine Delivery and Patient Monitoring. Microneedles for Drug and Vaccine Delivery and Patient Monitoring 235 258 .
Ismaiel A. Tekko & Thakur Raghu Raj Singh. 2018. Microneedles for Drug and Vaccine Delivery and Patient Monitoring. Microneedles for Drug and Vaccine Delivery and Patient Monitoring 283 306 .
Aaron McConville, Catherine Hegarty & James Davis. (2018) Mini-Review: Assessing the Potential Impact of Microneedle Technologies on Home Healthcare Applications. Medicines 5:2, pages 50.
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Jessica C Joyce, Timothy D Carroll, Marcus L Collins, Min-hsin Chen, Linda Fritts, Joseph C Dutra, Tracy L Rourke, James L Goodson, Michael B McChesney, Mark R Prausnitz & Paul A Rota. (2018) A Microneedle Patch for Measles and Rubella Vaccination Is Immunogenic and Protective in Infant Rhesus Macaques. The Journal of Infectious Diseases 218:1, pages 124-132.
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Shubhmita Bhatnagar, Amala Saju, Krishna Deepthi Cheerla, Sudeep Kumar Gade, Prashant Garg & Venkata Vamsi Krishna Venuganti. (2017) Corneal delivery of besifloxacin using rapidly dissolving polymeric microneedles. Drug Delivery and Translational Research 8:3, pages 473-483.
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Min Jung Kim, Seok Chan Park, Binod Rizal, Giselle Guanes, Seung-Ki Baek, Jung-Hwan Park, Amy R. Betz & Seong-O Choi. (2018) Fabrication of Circular Obelisk-Type Multilayer Microneedles Using Micro-Milling and Spray Deposition. Frontiers in Bioengineering and Biotechnology 6.
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Ji Yeon Hong, Eun Jung Ko, Sun Young Choi, Kapsok Li, A Reum Kim, Jin O Park & Beom Joon Kim. (2018) Efficacy and safety of a novel, soluble microneedle patch for the improvement of facial wrinkle. Journal of Cosmetic Dermatology 17:2, pages 235-241.
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R.M. Fertig, A.C. Gamret, J. Cervantes & A. Tosti. (2018) Microneedling for the treatment of hair loss?. Journal of the European Academy of Dermatology and Venereology 32:4, pages 564-569.
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Theresa K. Resch, Yuhuan Wang, Sung-Sil Moon, Jessica Joyce, Song Li, Mark Prausnitz & Baoming Jiang. (2018) Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice. Scientific Reports 8:1.
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Sanjiv Sharma, Ahmed El-Laboudi, Monika Reddy, Narvada Jugnee, Sujan Sivasubramaniyam, Mohamed El Sharkawy, Pantelis Georgiou, Desmond Johnston, Nick Oliver & Anthony E. G. Cass. (2018) A pilot study in humans of microneedle sensor arrays for continuous glucose monitoring. Analytical Methods 10:18, pages 2088-2095.
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Maurizio Ventre, Valerio Coppola, Maria Iannone, Paolo A. Netti, Ismaiel Tekko, Eneko Larrañeta, Aoife M. Rodgers, Christopher J. Scott, Adrien Kissenpfennig, Ryan F. Donnelly, Shaheer Maher, Dusan Losic, Anne George & Amsaveni Ramachandran. 2018. Nanotechnologies in Preventive and Regenerative Medicine. Nanotechnologies in Preventive and Regenerative Medicine 93 206 .
Camila N. Lemos, Francieli Pereira, Luciana F. Dalmolin, Camila Cubayachi, Danielle N. Ramos & Renata F.V. Lopez. 2018. Nanostructures for the Engineering of Cells, Tissues and Organs. Nanostructures for the Engineering of Cells, Tissues and Organs 187 248 .
Jicheng Yu, Yuqi Zhang, Anna R Kahkoska & Zhen Gu. (2017) Bioresponsive transcutaneous patches. Current Opinion in Biotechnology 48, pages 28-32.
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Anureet Arora, Manju Nagpal & Geeta Aggarwal. (2017) Microneedle Mediated Vaccine Delivery: A Comprehensive Review. Journal of Pharmaceutical Technology, Research and Management 5:2, pages 163-184.
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Anne Marit de Groot, Guangsheng Du, Juha Mönkäre, Anouk C.M. Platteel, Femke Broere, Joke A. Bouwstra & Alice J.A.M. Sijts. (2017) Hollow microneedle-mediated intradermal delivery of model vaccine antigen-loaded PLGA nanoparticles elicits protective T cell-mediated immunity to an intracellular bacterium. Journal of Controlled Release 266, pages 27-35.
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Cristina G. Macedo, Amit K. Jain, Michelle Franz-Montan, Marcelo H. Napimoga, Juliana T. Clemente-Napimoga & Harvinder Singh Gill. (2017) Microneedles enhance topical delivery of 15-deoxy-Δ 12,14 -prostaglandin J 2 and reduce nociception in temporomandibular joint of rats. Journal of Controlled Release 265, pages 22-29.
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Shubhmita Bhatnagar, Kaushalkumar Dave & Venkata Vamsi Krishna Venuganti. (2017) Microneedles in the clinic. Journal of Controlled Release 260, pages 164-182.
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Chao Wang, Yanqi Ye, Quanyin Hu, Adriano Bellotti & Zhen Gu. (2017) Tailoring Biomaterials for Cancer Immunotherapy: Emerging Trends and Future Outlook. Advanced Materials 29:29, pages 1606036.
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E. Stein Esser, Joanna A. Pulit-Penaloza, Haripriya Kalluri, Devin McAllister, Elena V. Vassilieva, Elizabeth Q. Littauer, Nadia Lelutiu, Mark R. Prausnitz, Richard W. Compans & Ioanna Skountzou. (2017) Microneedle patch delivery of influenza vaccine during pregnancy enhances maternal immune responses promoting survival and long-lasting passive immunity to offspring. Scientific Reports 7:1.
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Mark R. Prausnitz. (2017) Engineering Microneedle Patches for Vaccination and Drug Delivery to Skin. Annual Review of Chemical and Biomolecular Engineering 8:1, pages 177-200.
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Ahlam A. Ali, Cian M. McCrudden, Joanne McCaffrey, John W. McBride, Grace Cole, Nicholas J. Dunne, Tracy Robson, Adrien Kissenpfennig, Ryan F. Donnelly & Helen O. McCarthy. (2017) DNA vaccination for cervical cancer; a novel technology platform of RALA mediated gene delivery via polymeric microneedles. Nanomedicine: Nanotechnology, Biology and Medicine 13:3, pages 921-932.
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Martha Chege, Aaron McConville & James Davis. (2017) Microneedle drug delivery systems: Appraising opportunities for improving safety and assessing areas of concern. Journal of Chemical Health & Safety 24:2, pages 6-14.
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Qin Zeng, Joshua M. Gammon, Lisa H. Tostanoski, Yu-Chieh Chiu & Christopher M. Jewell. (2016) In Vivo Expansion of Melanoma-Specific T Cells Using Microneedle Arrays Coated with Immune-Polyelectrolyte Multilayers . ACS Biomaterials Science & Engineering 3:2, pages 195-205.
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