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Review

From nose to brain: understanding transport capacity and transport rate of drugs

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Pages 1159-1168 | Published online: 25 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (18)

Nitish Kumar, Bharat Khurana & Daisy Arora. (2023) Nose-to-brain drug delivery for the treatment of glioblastoma multiforme: nanotechnological interventions. Pharmaceutical Development and Technology 0:0, pages 1-16.
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Jie Li, Jiaqian Zhao, Tiantian Tan, Mengmeng Liu, Zhaowu Zeng, Yiying Zeng, Lele Zhang, Chaomei Fu, Dajing Chen & Tian Xie. (2020) Nanoparticle Drug Delivery System for Glioma and Its Efficacy Improvement Strategies: A Comprehensive Review. International Journal of Nanomedicine 15, pages 2563-2582.
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Rania M. Hathout, Sherweit H. El-Ahmady & AbdelKader A. Metwally. (2018) Curcumin or bisdemethoxycurcumin for nose-to-brain treatment of Alzheimer disease? A bio/chemo-informatics case study. Natural Product Research 32:24, pages 2873-2881.
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Amrish Kumar & Sunil Kumar Jain. (2017) Preliminary studies for the development of intranasal nanoemulsion containing CNS agent: emphasizing the utilization of cut and weigh method. Artificial Cells, Nanomedicine, and Biotechnology 45:3, pages 515-521.
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Juilee A. Kulkarni & Amelia M. Avachat. (2017) Pharmacodynamic and pharmacokinetic investigation of cyclodextrin-mediated asenapine maleate in situ nasal gel for improved bioavailability. Drug Development and Industrial Pharmacy 43:2, pages 234-245.
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Guangxiu Deng & Lan Jin. (2017) The effects of vasoactive intestinal peptide in neurodegenerative disorders. Neurological Research 39:1, pages 65-72.
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Adryana Clementino, Mellissa Batger, Gabriela Garrastazu, Michele Pozzoli, Elena Del Favero, Valeria Rondelli, Bianca Gutfilen, Thiago Barboza, Maria B Sukkar, Sergio A L Souza, Laura Cantù & Fabio Sonvico. (2016) The nasal delivery of nanoencapsulated statins – an approach for brain delivery. International Journal of Nanomedicine 11, pages 6575-6590.
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Débora B Vieira & Lionel F Gamarra. (2016) Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier. International Journal of Nanomedicine 11, pages 5381-5414.
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Surjyanarayan Mandal, Snigdha Das Mandal, Krishna Chuttani, Krutika K Sawant & Bharat Bhushan Subudhi. (2016) Design and evaluation of mucoadhesive microemulsion for neuroprotective effect of ibuprofen following intranasal route in the MPTP mice model. Drug Development and Industrial Pharmacy 42:8, pages 1340-1350.
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P. R. Ravi, N. Aditya, S. Patil & L. Cherian. (2015) Nasal in-situ gels for delivery of rasagiline mesylate: improvement in bioavailability and brain localization. Drug Delivery 22:7, pages 903-910.
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Sylvain Martel. (2015) Learning from our failures in blood–brain permeability: what can be done for new drug discovery?. Expert Opinion on Drug Discovery 10:3, pages 207-211.
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Sumit Sharma, Shikha Lohan & R. S. R. Murthy. (2014) Formulation and characterization of intranasal mucoadhesive nanoparticulates and thermo-reversible gel of levodopa for brain delivery. Drug Development and Industrial Pharmacy 40:7, pages 869-878.
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Xingguo Zhang, Lin Liu, Guobao Chai, Xiangyi Zhang & Fanzhu Li. (2013) Brain pharmacokinetics of neurotoxin-loaded PLA nanoparticles modified with chitosan after intranasal administration in awake rats. Drug Development and Industrial Pharmacy 39:11, pages 1618-1624.
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Sermin Genc, Zeynep Zadeoglulari, Meryem Gulfem Oner, Kursad Genc & Murat Digicaylioglu. (2011) Intranasal erythropoietin therapy in nervous system disorders. Expert Opinion on Drug Delivery 8:1, pages 19-32.
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Barbara Luppi, Federica Bigucci, Teresa Cerchiara & Vittorio Zecchi. (2010) Chitosan-based hydrogels for nasal drug delivery: from inserts to nanoparticles. Expert Opinion on Drug Delivery 7:7, pages 811-828.
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Murat Digicaylioglu. (2010) Erythropoietin in stroke: quo vadis. Expert Opinion on Biological Therapy 10:6, pages 937-949.
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Mellar P Davis. (2010) Recent development in therapeutics for breakthrough pain. Expert Review of Neurotherapeutics 10:5, pages 757-773.
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Bin Kong, Yong Sun, Yongjian Li & Dejian Hu. (2009) Preparation and the Influencing Factors of Timozolomide Liposomes. Artificial Cells, Blood Substitutes, and Biotechnology 37:6, pages 279-282.
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