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Drug Safety Evaluation

Efficacy, safety, and current applications of brimonidine

, MD, , MD & , MD
Pages 795-799 | Published online: 04 Nov 2008

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Read on this site (9)

Jihei Sara Lee & Chan Yun Kim. (2022) Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy. Expert Review of Clinical Pharmacology 15:8, pages 911-919.
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Pankaj Kumar Sharma & Meenakshi Kanwar Chauhan. (2021) Optimization and Characterization of Brimonidine Tartrate Nanoparticles-loaded In Situ Gel for the Treatment of Glaucoma. Current Eye Research 46:11, pages 1703-1716.
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Pankaj Kumar Sharma, Nidhi Sandal & Meenakshi Kanwar Chauhan. (2021) Evaluation of precorneal residence time of brimonidine tartrate nanoparticles loaded in situ gel using gamma scintigraphy. Inorganic and Nano-Metal Chemistry 51:5, pages 701-708.
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Stacey L Ackerman, Gail L Torkildsen, Eugene Mclaurin & Jason L Vittitow. (2019) Low‐dose brimonidine for relief of ocular redness: integrated analysis of four clinical trials. Clinical and Experimental Optometry 102:2, pages 131-139.
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Gail L. Torkildsen, Christine M. Sanfilippo, Heleen H. DeCory & Paul J. Gomes. (2018) Evaluation of Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution, 0.025% for Treatment of Ocular Redness. Current Eye Research 43:1, pages 43-51.
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Sky K Chew, Simon E Skalicky & Ivan Goldberg. (2014) Brinzolamide plus brimonidine for the treatment of glaucoma: an update. Expert Opinion on Pharmacotherapy 15:16, pages 2461-2471.
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Elad Moisseiev, Shimon Kurtz, Moshe Lazar & Gabi Shemesh. (2013) Intraocular pressure reduction using a fixed combination of timolol maleate 0.5% and brimonidine tartrate 0.2% administered three times daily. Clinical Ophthalmology 7, pages 1269-1273.
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M Reza Razeghinejad, Andrea K Sawchyn & L Jay Katz. (2010) Fixed combinations of dorzolamide-timolol and brimonidine-timolol in the management of glaucoma. Expert Opinion on Pharmacotherapy 11:6, pages 959-968.
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Ciro Costagliola, Roberto dell'Omo, Mario R Romano, Michele Rinaldi, Lucia Zeppa & Francesco Parmeggiani. (2009) Pharmacotherapy of intraocular pressure: part I. Parasympathomimetic, sympathomimetic and sympatholytics. Expert Opinion on Pharmacotherapy 10:16, pages 2663-2677.
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Articles from other publishers (28)

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Fikret Ucar & Halil İbrahim Yener. (2022) Can bleeding in trabeculectomy be decreased? Effectiveness of brimonidine pre-treatment. European Journal of Ophthalmology 32:6, pages 3476-3481.
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Julien Ringuet, Caroline Lajoie, Serge Bourgault, David Simonyan & Marie‐Claude Houle. (2022) The benefit of scratch patch testing to demonstrate ocular contact allergy to brimonidine tartrate. Contact Dermatitis 87:4, pages 336-342.
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Nada M. El Hoffy, Engy A. Abdel Azim, Rania M. Hathout, Marwa A. Fouly & Seham A. Elkheshen. (2021) Glaucoma: Management and Future Perspectives for Nanotechnology-Based Treatment Modalities. European Journal of Pharmaceutical Sciences 158, pages 105648.
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N Cimolai. (2020) A review of neuropsychiatric adverse events from topical ophthalmic brimonidine. Human & Experimental Toxicology 39:10, pages 1279-1290.
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Alexander K. Schuster, Carl Erb, Esther M. Hoffmann, Thomas Dietlein & Norbert Pfeiffer. (2020) The Diagnosis and Treatment of Glaucoma. Deutsches Ärzteblatt international.
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Doina Gherghel. (2020) The use of ophthalmic medications in pregnancy: What should we know?. Optician 2020:2, pages 8224-1.
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Sunu Mathew, Alon Harris, Colin M. Ridenour, Barbara M. Wirostko, Kendall M. Burgett, Molly D. Scripture & Brent Siesky. (2019) Management of Glaucoma in Pregnancy. Journal of Glaucoma 28:10, pages 937-944.
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Eugene McLaurin, Megan E. Cavet, Paul J. Gomes & Joseph B. Ciolino. (2018) Brimonidine Ophthalmic Solution 0.025% for Reduction of Ocular Redness: A Randomized Clinical Trial. Optometry and Vision Science 95:3, pages 264-271.
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Yuxiang Yuan, Ying Zhu, Yinwei Song, Yin Zhao, Xiaoqin Yan, Wei Chen, Mu Li, Jieling Gong, Ketao Mu, Junming Wang, Hong Zhang & Zhiqi Chen. (2018) Morphological and Functional Changes of Locus Coeruleus in Patients with Primary Open-Angle Glaucoma and Animal Models. Neuroscience 372, pages 141-153.
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Paul Harasymowycz, Catherine Birt, Patrick Gooi, Lisa Heckler, Cindy Hutnik, Delan Jinapriya, Lesya Shuba, David Yan & Radmila Day. (2016) Medical Management of Glaucoma in the 21st Century from a Canadian Perspective. Journal of Ophthalmology 2016, pages 1-22.
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Samin Hong, Sueng-Han Han, Chan Yun Kim, Kang Yoon Kim, Yoo Kyung Song & Gong Je Seong. (2015) Brimonidine reduces TGF-beta-induced extracellular matrix synthesis in human Tenon’s fibroblasts. BMC Ophthalmology 15:1.
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Deepak Sambhara & Ahmad A. Aref. (2013) Glaucoma management: relative value and place in therapy of available drug treatments. Therapeutic Advances in Chronic Disease 5:1, pages 30-43.
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MASAHIKO AYAKI, ATSUO IWASAWA & YOSHIMI NIWANO. (2012) Cell Viability Score as an Integrated Indicator for Cytotoxicity of Benzalkonium Chloride-Containing Antiglaucoma Eyedrops. Biocontrol Science 17:3, pages 121-128.
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Matthias GruebJoerg MielkeJens Martin RohrbachTorsten Schlote. (2011) Effect of Brimonidine on Corneal Thickness. Journal of Ocular Pharmacology and Therapeutics 27:5, pages 503-509.
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M. Reza Razeghinejad, Tak Yee Tania Tai, Scott J. Fudemberg & L. Jay Katz. (2011) Pregnancy and Glaucoma. Survey of Ophthalmology 56:4, pages 324-335.
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Gabi Shemesh, Elad Moisseiev, Moshe Lazar & Anat Kesler. (2011) Effect of brimonidine tartrate 0.10% ophthalmic solution on pupil diameter. Journal of Cataract and Refractive Surgery 37:3, pages 486-489.
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Alan R. Katritzky, C. Dennis Hall, Bahaa El-Dien M. El-Gendy & Bogdan Draghici. (2010) Tautomerism in drug discovery. Journal of Computer-Aided Molecular Design 24:6-7, pages 475-484.
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P. J. Fitzgerald. (2009) Is elevated noradrenaline an aetiological factor in a number of diseases?. Autonomic and Autacoid Pharmacology 29:4, pages 143-156.
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