Serene M.L. Lee, Armin KernKarl-Walter JauchReinhard ThaslerHanno NiessWolfgang E. Thasler. (2023) Cold Preservation of Human Hepatocytes with High Viability. Biopreservation and Biobanking 21:4, pages 367-377.
Crossref
Melissa Anne Tutty, Dania Movia & Adriele Prina-Mello. (2022) Three-dimensional (3D) liver cell models - a tool for bridging the gap between animal studies and clinical trials when screening liver accumulation and toxicity of nanobiomaterials. Drug Delivery and Translational Research 12:9, pages 2048-2074.
Crossref
Sheila Annie Peters. 2021. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations
193
216
.
Camilla Bernasconi, Olavi Pelkonen, Tommy B. Andersson, Judy Strickland, Iwona Wilk-Zasadna, David Asturiol, Thomas Cole, Roman Liska, Andrew Worth, Ursula Müller-Vieira, Lysiane Richert, Christophe Chesne & Sandra Coecke. (2019) Validation of in vitro methods for human cytochrome P450 enzyme induction: Outcome of a multi-laboratory study. Toxicology in Vitro 60, pages 212-228.
Crossref
P. Viviani, A. L. Lifschitz, M. L. Maté, J. P. García, C. E. Lanusse & G. L. Virkel. (2018) Assessment of the pharmacological interactions between the nematodicidal fenbendazole and the flukicidal triclabendazole: In vitro studies with bovine liver microsomes and slices. Journal of Veterinary Pharmacology and Therapeutics 41:3, pages 476-484.
Crossref
Nicole Beißner, Antonio Bolea Albero, Jendrik Füller, Thomas Kellner, Lothar Lauterboeck, Jinghu Liang, Markus Böl, Birgit Glasmacher, Christel C. Müller-Goymann & Stephan Reichl. (2018) Improved in vitro models for preclinical drug and formulation screening focusing on 2D and 3D skin and cornea constructs. European Journal of Pharmaceutics and Biopharmaceutics 126, pages 57-66.
Crossref
Alba Balmori, Mourad Chioua, Raimon Puig de la Bellacasa, Roger Estrada‐Tejedor, Lhassane Ismaili, José Marco‐Contelles & José I. Borrell. (2017)
5‐Amino‐6,7,8,9‐Tetrahydrobenzo[
b
][1,8]Naphthyridin‐2(1
H
)‐One: The first Example of a new Family of HuperTacrines for Alzheimer's Disease Therapy
. ChemistrySelect 2:8, pages 2605-2610.
Crossref
Xiaoqian Zhang, Juan Lu, Bin He, Lingling Tang, Xiaoli Liu, Danhua Zhu, Hongcui Cao, Yingjie Wang & Lanjuan Li. (2017) A tryptophan derivative, ITE, enhances liver cell metabolic functions in vitro. International Journal of Molecular Medicine 39:1, pages 101-112.
Crossref
Leonard J. Nelson, Katie Morgan, Philipp Treskes, Kay Samuel, Catherine J. Henderson, Claire LeBled, Natalie Homer, M. Helen Grant, Peter C. Hayes & John N. Plevris. (2017) Human Hepatic HepaRG Cells Maintain an Organotypic Phenotype with High Intrinsic CYP450 Activity/Metabolism and Significantly Outperform Standard HepG2/C3A Cells for Pharmaceutical and Therapeutic Applications. Basic & Clinical Pharmacology & Toxicology 120:1, pages 30-37.
Crossref
T. Hartung. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III
150
155
.
Ran‐Ran Zhang, Yun‐Wen Zheng & Hideki Taniguchi. 2016. Stem Cells in Toxicology and Medicine. Stem Cells in Toxicology and Medicine
145
154
.
Bernardo Brito Palma, Daniela Moutinho, Philippe Urban, José Rueff & Michel Kranendonk. (2016) Cytochrome P450 expression system for high-throughput real-time detection of genotoxicity: Application to the study of human CYP1A2 variants. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 806, pages 24-33.
Crossref
Madison Davis & Brendan D. Stamper. (2016) TAMH: A Useful In Vitro Model for Assessing Hepatotoxic Mechanisms. BioMed Research International 2016, pages 1-9.
Crossref
Vaishali Sahasrabudhe, Tong Zhu, Alfin Vaz & Susanna Tse. (2015) Drug Metabolism and Drug Interactions: Potential Application to Antituberculosis Drugs. Journal of Infectious Diseases 211:suppl 3, pages S107-S114.
Crossref
Robim M. Rodrigues, Joery De Kock, Tatyana Y. Doktorova, Vera Rogiers & Tamara Vanhaecke. 2015. Protocols in In Vitro Hepatocyte Research. Protocols in In Vitro Hepatocyte Research
279
285
.
Sonia Sentellas, Oriol Morales-Ibanez, Miriam Zanuy & Joan J. Albertí. (2014) GSSG/GSH ratios in cryopreserved rat and human hepatocytes as a biomarker for drug induced oxidative stress. Toxicology in Vitro 28:5, pages 1006-1015.
Crossref
Wan Yahya, Nahrizul Kadri & Fatimah Ibrahim. (2014) Cell Patterning for Liver Tissue Engineering via Dielectrophoretic Mechanisms. Sensors 14:7, pages 11714-11734.
Crossref
Alan Boobis, Alessandro Chiodini, Jeljer Hoekstra, Pagona Lagiou, Hildegard Przyrembel, Josef Schlatter, Katrin Schütte, Hans Verhagen & Bernhard Watzl. (2013) Critical appraisal of the assessment of benefits and risks for foods, ‘BRAFO Consensus Working Group’. Food and Chemical Toxicology 55, pages 659-675.
Crossref
Frank A Barile. 2013. Principles of Toxicology Testing. Principles of Toxicology Testing
118
127
.
Han Hui CheongJeyakumar MasilamaniChun Yong Eric ChanSui Yung ChanToan Thang Phan. (2013) Metabolically Functional Hepatocyte-Like Cells from Human Umbilical Cord Lining Epithelial Cells. ASSAY and Drug Development Technologies 11:2, pages 130-138.
Crossref
N. C. Talbot, T. J. Caperna & W. M. Garrett. (2013) GROWTH AND DEVELOPMENT SYMPOSIUM: Development, characterization, and use of a porcine epiblast-derived liver stem cell line: ARS-PICM-1912. Journal of Animal Science 91:1, pages 66-77.
Crossref
Alexander V. LyubimovHiroshi Komura & Masahiro Iwaki. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
41
.
Yi Ling Teo, Manit Saetaew, Suthan Chanthawong, Yoon Sim Yap, Eric Chun Yong Chan, Han Kiat Ho & Alexandre Chan. (2012) Effect of CYP3A4 inducer dexamethasone on hepatotoxicity of lapatinib: clinical and in vitro evidence. Breast Cancer Research and Treatment 133:2, pages 703-711.
Crossref
Vasiliy N. Goral & Po Ki Yuen. (2011) Microfluidic Platforms for Hepatocyte Cell Culture: New Technologies and Applications. Annals of Biomedical Engineering 40:6, pages 1244-1254.
Crossref
Brigitte Altmann, Ralf Ahrens, Alexander Welle, Heinz Dinglreiter, Marc Schneider & Andreas Schober. (2011) Microstructuring of multiwell plates for three-dimensional cell culture applications by ultrasonic embossing. Biomedical Microdevices 14:2, pages 291-301.
Crossref
Sheila Annie Peters. 2012. Physiologically‐Based Pharmacokinetic (PBPK) Modeling and Simulations. Physiologically‐Based Pharmacokinetic (PBPK) Modeling and Simulations
119
151
.
Alexander V. LyubimovLin Xu, Biplab Das & Chandra Prakash. 2011. Encyclopedia of Drug Metabolism and Interactions. Encyclopedia of Drug Metabolism and Interactions
1
35
.
Chunqi Li, Liqing Luo, Jessica Awerman & Patricia McGrath. 2011. Zebrafish. Zebrafish
103
115
.
Chih-Chieh Chu, Kao-Lu Pan, Hsien-Tsung Yao & John Tsu-An Hsu. (2011) Development of a whole-cell screening system for evaluation of the human CYP1A2-mediated metabolism. Biotechnology and Bioengineering 108:12, pages 2932-2940.
Crossref
Ian E. Templeton, J. Brian Houston & Aleksandra Galetin. (2011) Predictive Utility of In Vitro Rifampin Induction Data Generated in Fresh and Cryopreserved Human Hepatocytes, Fa2N-4, and HepaRG Cells. Drug Metabolism and Disposition 39:10, pages 1921-1929.
Crossref
Tom De Bruyn, Zhi-Wei Ye, Annelies Peeters, Jasminder Sahi, Myriam Baes, Patrick F. Augustijns & Pieter P. Annaert. (2011) Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes. European Journal of Pharmaceutical Sciences 43:4, pages 297-307.
Crossref
Benjamin Lemaire, Michaël Beck, Mélanie Jaspart, Cathy Debier, Pedro Buc Calderon, Jean-Pierre Thomé & Jean-François Rees. (2011) Precision-Cut Liver Slices of Salmo salar as a tool to investigate the oxidative impact of CYP1A-mediated PCB 126 and 3-methylcholanthrene metabolism. Toxicology in Vitro 25:1, pages 335-342.
Crossref
Rui M. Tostões, Sofia B. Leite, Joana P. Miranda, Marcos Sousa, Daniel I.C. Wang, Manuel J.T. Carrondo & Paula M. Alves. (2011) Perfusion of 3D encapsulated hepatocytes-A synergistic effect enhancing long-term functionality in bioreactors. Biotechnology and Bioengineering 108:1, pages 41-49.
Crossref
Michael Sinz, Sean Kim, Stephen Ferguson & Edward LeCluyse. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia
1
31
.
Lilian G. Yengi. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia
1
23
.
Ryan R. Willard, Nancy W. Shappell, John H. Meekin, Neil C. Talbot & Thomas J. Caperna. (2009) Cytochrome P450 expression profile of the PICM-19H pig liver cell line: potential application to rapid liver toxicity assays. In Vitro Cellular & Developmental Biology - Animal 46:1, pages 11-19.
Crossref
Ragini Vuppugalla, Sean Kim, Tatyana Zvyaga, Yong-hae Han, Praveen Balimane, Punit Marathe & A. David Rodrigues. 2010. Enzyme- and Transporter-Based Drug-Drug Interactions. Enzyme- and Transporter-Based Drug-Drug Interactions
585
624
.
Jens Niklas, Fozia Noor & Elmar Heinzle. (2009) Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2. Toxicology and Applied Pharmacology 240:3, pages 327-336.
Crossref
Dermot F. McGinnity, George Zhang, Jane R. Kenny, Geraldine A. Hamilton, Sara Otmani, Karen R. Stams, Suzzette Haney, Patrick Brassil, David M. Stresser & Robert J. Riley. (2009) Evaluation of Multiple in Vitro Systems for Assessment of CYP3A4 Induction in Drug Discovery: Human Hepatocytes, Pregnane X Receptor Reporter Gene, and Fa2N-4 and HepaRG Cells. Drug Metabolism and Disposition 37:6, pages 1259-1268.
Crossref
Marc Vermeir, Alex Hemeryck, Filip Cuyckens, Andres Francesch, Marc Bockx, Jos Van Houdt, Kathleen Steemans, Geert Mannens, Pablo Avilés & Roland De Coster. (2009) In vitro studies on the metabolism of trabectedin (YONDELIS®) in monkey and man, including human CYP reaction phenotyping. Biochemical Pharmacology 77:10, pages 1642-1654.
Crossref
Deepak Dalvie, R. Scott Obach, Ping Kang, Chandra Prakash, Cho-Ming Loi, Susan Hurst, Angus Nedderman, Lance Goulet, Evan Smith, Hai-Zhi Bu & Dennis A. Smith. (2009) Assessment of Three Human in Vitro Systems in the Generation of Major Human Excretory and Circulating Metabolites. Chemical Research in Toxicology 22:2, pages 357-368.
Crossref
Lilian G. Yengi. 2009. Drug Metabolism Handbook. Drug Metabolism Handbook
65
87
.
Michael Sinz, Sean Kim, Stephen Ferguson & Edward Lecluyse. 2009. Drug Metabolism Handbook. Drug Metabolism Handbook
359
389
.
Kazunobu Aoyama, Kouichi Yoshinari, Hye-Ji Kim, Kiyoshi Nagata & Yasushi Yamazoe. (2009) Simultaneous Expression of Plural Forms of Human Cytochrome P450 at Desired Ratios in HepG2 Cells: Adenovirus-mediated Tool for Cytochrome P450 Reconstitution. Drug Metabolism and Pharmacokinetics 24:3, pages 209-217.
Crossref
Matthew D. Thompson & Henry J. Thompson. 2009.
1
54
.
Raymond F. Schinazi, Steven J. Coats, Leda C. Bassit, Johan Lennerstrand, James H. Nettles & Selwyn J. Hurwitz. 2009. Antiviral Strategies. Antiviral Strategies
25
51
.
José V. Castell & María José Gómez-Lechón. 2009. Hepatocyte Transplantation. Hepatocyte Transplantation
35
46
.
Amelie Lupp, Reinhild Glöckner, Joachim Etzrodt & Dieter Müller. (2008) Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility. Analytical and Bioanalytical Chemistry 392:6, pages 1173-1184.
Crossref
Olavi Pelkonen, Miia Turpeinen, Jukka Hakkola, Paavo Honkakoski, Janne Hukkanen & Hannu Raunio. (2008) Inhibition and induction of human cytochrome P450 enzymes: current status. Archives of Toxicology 82:10, pages 667-715.
Crossref
Esther G. van de Kerkhof, Inge A. M. de Graaf, Anna-Lena B. Ungell & Geny M. M. Groothuis. (2008) Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro. Drug Metabolism and Disposition 36:3, pages 604-613.
Crossref
Michael J. Liguori, Eric A.G. Blomme & Jeffrey F. Waring. (2008) Trovafloxacin-Induced Gene Expression Changes in Liver-Derived in Vitro Systems: Comparison of Primary Human Hepatocytes to HepG2 Cells. Drug Metabolism and Disposition 36:2, pages 223-233.
Crossref
P Martin, R Riley, D J Back & A Owen. (2008) Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells. British Journal of Pharmacology 153:4, pages 805-819.
Crossref
Kevin J. Coe, Yankai Jia, Han Kiat Ho, Peter Rademacher, Theo K. Bammler, Richard P. Beyer, Frederico M. Farin, Libby Woodke, Stephen R. Plymate, Nelson Fausto & Sidney D. Nelson. (2007) Comparison of the Cytotoxicity of the Nitroaromatic Drug Flutamide to Its Cyano Analogue in the Hepatocyte Cell Line TAMH: Evidence for Complex I Inhibition and Mitochondrial Dysfunction Using Toxicogenomic Screening. Chemical Research in Toxicology 20:9, pages 1277-1290.
Crossref
Frank Barile. 2007. Principles of Toxicology Testing. Principles of Toxicology Testing
175
202
.
María José Gómez-Lechón, José Vicente Castell & María Teresa Donato. (2007) Hepatocytes—the choice to investigate drug metabolism and toxicity in man: In vitro variability as a reflection of in vivo. Chemico-Biological Interactions 168:1, pages 30-50.
Crossref
Michael W. Sinz & Sean Kim. (2006) Stem cells, immortalized cells and primary cells in ADMET assays. Drug Discovery Today: Technologies 3:1, pages 79-85.
Crossref