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Expert Review of Neurotherapeutics Volume 7, 2007 - Issue 6
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Review

Genetics of Parkinson’s disease and parkinsonism

Michael R Douglas Clinical Lecturer, University of Birmingham Medical School, Vincent Drive, Edgbaston, Birmingham, B15 2TT, UK. [email protected]
,
Alistair J Lewthwaite Clinical Research Fellow, University of Birmingham Medical School, Edgbaston, Birmingham B15 2TT, UK. [email protected]
&
David J Nicholl Neurology Consultant and Honorary Senior Lecturer, Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK. [email protected]
Pages 657-666 | Published online: 10 Jan 2014

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Elena Miñones-Moyano, Marc R. Friedländer, Joan Pallares, Birgit Kagerbauer, Sílvia Porta, Georgia Escaramís, Isidre Ferrer, Xavier Estivill & Eulàlia Martí. (2013) Upregulation of a small vault RNA (svtRNA2-1a) is an early event in Parkinson disease and induces neuronal dysfunction. RNA Biology 10:7, pages 1093-1106.
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Michael R Douglas. (2013) Gene therapy for Parkinson’s disease: state-of-the-art treatments for neurodegenerative disease. Expert Review of Neurotherapeutics 13:6, pages 695-705.
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Miao Cai, Jun Tian, Guo-hua Zhao, Wei Luo & Bao-rong Zhang. (2011) Study of Methylation Levels of Parkin Gene Promoter in Parkinson's Disease Patients. International Journal of Neuroscience 121:9, pages 497-502.
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Roberto Santucci, Federica Sinibaldi, Antonella Patriarca, Daniele Santucci & Laura Fiorucci. (2010) Misfolded proteins and neurodegeneration: role of non-native cytochrome c in cell death. Expert Review of Proteomics 7:4, pages 507-517.
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George R. Uhl, Tomas Drgon, Catherine Johnson & Qing-Rong Liu. (2009) Addiction Genetics and Pleiotropic Effects of Common Haplotypes that Make Polygenic Contributions to Vulnerability to Substance Dependence. Journal of Neurogenetics 23:3, pages 272-282.
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I. S. Pienaar, L. A. Kellaway, V. A. Russell, A. D. Smith, D. J. Stein, M. J. Zigmond & W. M. U. Daniels. (2008) Maternal separation exaggerates the toxic effects of 6-hydroxydopamine in rats: Implications for neurodegenerative disorders. Stress 11:6, pages 448-456.
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Kah-Leong Lim. (2007) Ubiquitin–proteasome system dysfunction in Parkinson’s disease: current evidence and controversies. Expert Review of Proteomics 4:6, pages 769-781.
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Articles from other publishers (17)

Gian Pal, Lola Cook, Jeanine Schulze, Jennifer Verbrugge, Roy N. Alcalay, Marcelo Merello, Carolyn M. Sue, Soraya Bardien, Vincenzo Bonifati, Sun Ju Chung, Tatiana Foroud, Emilia Gatto, Anne Hall, Nobutaka Hattori, Tim Lynch, Karen Marder, Deborah Mascalzoni, Ivana Novaković, Avner Thaler, Deborah Raymond, Mehri Salari, Ali Shalash, Oksana Suchowersky, Niccolò E. Mencacci, Tanya Simuni, Rachel Saunders‐Pullman & Christine Klein. (2023) Genetic Testing in Parkinson's Disease. Movement Disorders 38:8, pages 1384-1396.
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Saima Owais & Yasir Hasan Siddique. (2023) A Comprehensive Study of miRNAs in Parkinson’s Disease: Diagnostics and Therapeutic Approaches. CNS & Neurological Disorders - Drug Targets 22:3, pages 353-380.
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Lamei Yuan, Xiangyu Chen, Zhi Song, Weidong Le, Wen Zheng, Xin Liu & Hao Deng. (2020) Extended Study of NUS1 Gene Variants in Parkinson's Disease. Frontiers in Neurology 11.
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Amy R. Dunn, Kristen M.S. O’Connell & Catherine C. Kaczorowski. (2019) Gene-by-environment interactions in Alzheimer’s disease and Parkinson’s disease. Neuroscience & Biobehavioral Reviews 103, pages 73-80.
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Shamsuzzama, Lalit Kumar & Aamir Nazir. (2017) Modulation of Alpha-synuclein Expression and Associated Effects by MicroRNA Let-7 in Transgenic C. elegans. Frontiers in Molecular Neuroscience 10.
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Lilach Soreq, Alessandro Guffanti, Nathan Salomonis, Alon Simchovitz, Zvi Israel, Hagai Bergman & Hermona Soreq. (2014) Long Non-Coding RNA and Alternative Splicing Modulations in Parkinson's Leukocytes Identified by RNA Sequencing. PLoS Computational Biology 10:3, pages e1003517.
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Lance M. Bollinger, Celsi E. Cowan & Thomas P. LaFontaine. (2012) Parkinson's Disease. Strength & Conditioning Journal 34:2, pages 50-54.
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Rachel Denyer & Michael R. Douglas. (2012) Gene Therapy for Parkinson's Disease. Parkinson's Disease 2012, pages 1-13.
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Elena Miñones-Moyano, Sílvia Porta, Georgia Escaramís, Raquel Rabionet, Susana Iraola, Birgit Kagerbauer, Yolanda Espinosa-Parrilla, Isidre Ferrer, Xavier Estivill & Eulàlia Martí. (2011) MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function. Human Molecular Genetics 20:15, pages 3067-3078.
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Oswaldo Lorenzo-Betancor, Lluís Samaranch, Elena García-Martín, Sebastián Cervantes, José A.G. Agúndez, Félix J. Jiménez-Jiménez, Hortensia Alonso-Navarro, Antonio Luengo, Francisco Coria, Elena Lorenzo, Jaione Irigoyen & Pau Pastor. (2011) LINGO1 gene analysis in Parkinson's disease phenotypes . Movement Disorders 26:4, pages 722-727.
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Donglai Sheng, Dianbo Qu, Ken Hon Hung Kwok, Seok Shin Ng, Adrian Yin Ming Lim, Sharon Siqi Aw, Charlie Wah Heng Lee, Wing Kin Sung, Eng King Tan, Thomas Lufkin, Suresh Jesuthasan, Mathavan Sinnakaruppan & Jianjun Liu. (2010) Deletion of the WD40 Domain of LRRK2 in Zebrafish Causes Parkinsonism-Like Loss of Neurons and Locomotive Defect. PLoS Genetics 6:4, pages e1000914.
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Derya R. Shimshek, Matthias Mueller, Christoph Wiessner, Tatjana Schweizer & P. Herman van der Putten. (2010) The HSP70 Molecular Chaperone Is Not Beneficial in a Mouse Model of α-synucleinopathy. PLoS ONE 5:4, pages e10014.
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George R. Uhl, Tomas Drgon, Catherine Johnson & Qing-Rong Liu. 2011. Addiction Medicine. Addiction Medicine 201 223 .
George R. Uhl, Tomas Drgon, Catherine Johnson, Chuan-Yun Li, Carlo Contoreggi, Judith Hess, Daniel Naiman & Qing-Rong Liu. (2008) Molecular Genetics of Addiction and Related Heritable Phenotypes. Annals of the New York Academy of Sciences 1141:1, pages 318-381.
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Marie-Francoise Chesselet, Sheila Fleming, Farzad Mortazavi & Bernd Meurers. (2008) Strengths and limitations of genetic mouse models of Parkinson's disease. Parkinsonism & Related Disorders 14, pages S84-S87.
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Marie-Francoise Chesselet & Pierre-Olivier Fernagut. 2008. Parkinson's Disease. Parkinson's Disease 285 294 .
Edith G McGeer & Patrick L McGeer. (2007) The Role of Anti-Inflammatory Agents in Parkinson???s Disease. CNS Drugs 21:10, pages 789-797.
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