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Drug Profile

A review of paliperidone palmitate

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Pages 1383-1397 | Published online: 09 Jan 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Laura Deruyver, Clément Rigaut, Alejandro Gomez-Perez, Pierre Lambert, Benoit Haut & Jonathan Goole. (2023) In vitro Evaluation of Paliperidone Palmitate Loaded Cubosomes Effective for Nasal-to-Brain Delivery. International Journal of Nanomedicine 18, pages 1085-1106.
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Zheng Shen, Jilong Ge, Jian Chen & Baiwang Sun. (2023) An Improved and Efficient Approach for the Synthesis of Paliperidone. Organic Preparations and Procedures International 55:6, pages 549-554.
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Peter M. Haddad & Christoph U. Correll. (2023) Long-acting antipsychotics in the treatment of schizophrenia: opportunities and challenges. Expert Opinion on Pharmacotherapy 24:4, pages 473-493.
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Ziwei Ma, Hongjuan Zhang, Yanjiao Wang & Xing Tang. (2019) Development and evaluation of intramuscularly administered nano/microcrystal suspension. Expert Opinion on Drug Delivery 16:4, pages 347-361.
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Georgios Schoretsanitis, Edoardo Spina, Christoph Hiemke & Jose de Leon. (2018) A systematic review and combined analysis of therapeutic drug monitoring studies for long-acting paliperidone. Expert Review of Clinical Pharmacology 11:12, pages 1237-1253.
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Rosaria Di Lorenzo, Michela Cameli, Chiara Piemonte, Marisa Bolondi, Giulia Landi, Gabriella Pollutri, Ludovica Spattini, Valentina Moretti & Paola Ferri. (2018) Clinical improvement, relapse and treatment adherence with paliperidone palmitate 1-month formulation: 1-year treatment in a naturalistic outpatient setting. Nordic Journal of Psychiatry 72:3, pages 214-220.
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Pierre Chue & James Chue. (2016) A critical appraisal of paliperidone long-acting injection in the treatment of schizoaffective disorder. Therapeutics and Clinical Risk Management 12, pages 109-116.
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Pierre Chue & James Chue. (2016) A review of aripiprazole long-acting injection. Current Medical Research and Opinion 32:3, pages 441-452.
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Gokay Alpak, Ahmet Unal, Feridun Bulbul, Ihsan Aksoy, Bahadir Demir & Haluk Asuman Savas. (2014) Hyperprolactinemia due to Paliperidone Palmitate and Treatment with Aripiprazole. Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology 24:3, pages 253-256.
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Larry Alphs, Cynthia A Bossie, Dong-Jing Fu, Yi-Wen Ma & Jennifer Kern Sliwa. (2014) Onset and persistence of efficacy by symptom domain with long-acting injectable paliperidone palmitate in patients with schizophrenia. Expert Opinion on Pharmacotherapy 15:7, pages 1029-1042.
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Silvio Caccia, Roberto William Invernizzi, Alessandro Nobili & Luca Pasina. (2013) A new generation of antipsychotics: pharmacology and clinical utility of cariprazine in schizophrenia. Therapeutics and Clinical Risk Management 9, pages 319-328.
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Articles from other publishers (32)

Sayali A. Nangare, Asif H. Ali, Kakasaheb R. Mahadik & Sharvil S. Patil. (2023) Fabrication, optimization and characterization of an osmotic push-pull drug delivery system for paliperidone. Journal of Taibah University Medical Sciences 18:6, pages 1511-1518.
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Amit Dabke, Saikat Ghosh, Pallavi Dabke, Krutika Sawant & Ajay Khopade. (2023) Revisiting the in-vitro and in-vivo considerations for in-silico modelling of complex injectable drug products. Journal of Controlled Release 360, pages 185-211.
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Yuanchao Jia, Yuxin Jiang, Yonglong He, Wanting Zhang, Jiahui Zou, Kosheli Thapa Magar, Hamza Boucetta, Chao Teng & Wei He. (2023) Approved Nanomedicine against Diseases. Pharmaceutics 15:3, pages 774.
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Yuhong Shi, Lin Chen, Motao Zhu & Yuliang Zhao. 2023. Nanomedicine. Nanomedicine 847 873 .
Yuhong Shi, Lin Chen, Motao Zhu & Yuliang Zhao. 2020. Nanomedicine. Nanomedicine 1 28 .
Wonsuk Shin, Dong Hyeon Lee, Min‐Kyoung Kim, Sang‐Hyuk Lee, Doo‐Yeoun Cho & Minji Bang. (2021) Clinical effectiveness of early treatment with paliperidone palmitate in schizophrenia: A retrospective real‐world study in South Korea. Early Intervention in Psychiatry 15:6, pages 1759-1767.
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Yujie Shi, An Lu, Xiangyu Wang, Zakia Belhadj, Jiancheng Wang & Qiang Zhang. (2021) A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives. Acta Pharmaceutica Sinica B 11:8, pages 2396-2415.
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Francisco José Toja-Camba, Nerea Gesto-Antelo, Olalla Maroñas, Eduardo Echarri Arrieta, Irene Zarra-Ferro, Miguel González-Barcia, Enrique Bandín-Vilar, Victor Mangas Sanjuan, Fernando Facal, Manuel Arrojo Romero, Angel Carracedo, Cristina Mondelo-García & Anxo Fernández-Ferreiro. (2021) Review of Pharmacokinetics and Pharmacogenetics in Atypical Long-Acting Injectable Antipsychotics. Pharmaceutics 13:7, pages 935.
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Georgios SchoretsanitisPierre BaumannAndreas ConcaOtto DietmaierGiancarlo GiupponiGerhard GründerMartina HahnXenia HartUrsula Havemann-ReineckeGudrun HefnerMaxim KuzinRainald MössnerDaria PiacentinoWerner SteimerGerald Zernig & Christoph Hiemke. (2021) Therapeutic Drug Monitoring of Long-Acting Injectable Antipsychotic Drugs. Therapeutic Drug Monitoring 43:1, pages 79-102.
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Maytinee Srifuengfung, Thanisorn Sukakul, Chanika Liangcheep & Natee Viravan. (2020) Paliperidone palmitate-induced facial angioedema: A case report. World Journal of Clinical Cases 8:20, pages 4876-4882.
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Abdullah Q. Khudhur, Nidhal K. Maraie & Ayad M.R. Raauf. (2020) Highlight on lipids and its use for covalent and non-covalent conjugations. Al Mustansiriyah Journal of Pharmaceutical Sciences 20:3, pages 1-13.
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Jung Suk Lee, Je-Yeon Yun, Shi Hyun Kang, Seung Jae Lee, Joon-Ho Choi, Beomwoo Nam, Seung-Hwan Lee, Young-Chul Chung & Chan-Hyung Kim. (2020) Korean Medication Algorithm for Schizophrenia 2019, Second Revision: Treatment of Psychotic Symptoms. Clinical Psychopharmacology and Neuroscience 18:3, pages 386-394.
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Harshita Gupta, Rutu Panchal, Niyati Acharya & Priti Jignesh Mehta. (2020) Controlled Parenteral Formulations: An Efficacious and Favourable Way to Deliver the Anti-psychotic Drugs. Current Psychiatry Research and Reviews 16:1, pages 42-59.
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Allan Radaic & Daniel Martins-de-Souza. (2020) The state of the art of nanopsychiatry for schizophrenia diagnostics and treatment. Nanomedicine: Nanotechnology, Biology and Medicine 28, pages 102222.
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Samantha Alvarez-Herrera, Raúl Escamilla, Oscar Medina-Contreras, Ricardo Saracco, Yvonne Flores, Gabriela Hurtado-Alvarado, José Luis Maldonado-García, Enrique Becerril-Villanueva, Gilberto Pérez-Sánchez & Lenin Pavón. (2020) Immunoendocrine Peripheral Effects Induced by Atypical Antipsychotics. Frontiers in Endocrinology 11.
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Michał Jóźwiak, Anna Filipowska, Ferdinando Fiorino & Marta Struga. (2020) Anticancer activities of fatty acids and their heterocyclic derivatives. European Journal of Pharmacology 871, pages 172937.
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Tushar Date, Kaushani Paul, Navneet Singh & Sanyog Jain. (2019) Drug–Lipid Conjugates for Enhanced Oral Drug Delivery. AAPS PharmSciTech 20:2.
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Chulei Yang, Xinchao Ji, Wenli Pan, Yi Liu, Lingli Zhou, Qiuyue Chen & Xing Tang. (2018) Paliperidone ascending controlled-release pellets with osmotic core and driven by delayed osmotic pressure. Journal of Drug Delivery Science and Technology 48, pages 193-199.
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Manli Huang, Liang Yu, Fen Pan, Shaojia Lu, Shaohua Hu, Jianbo Hu, Jinkai Chen, Pingbo Jin, Hongli Qi & Yi Xu. (2018) A randomized, 13-week study assessing the efficacy and metabolic effects of paliperidone palmitate injection and olanzapine in first-episode schizophrenia patients. Progress in Neuro-Psychopharmacology and Biological Psychiatry 81, pages 122-130.
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Danielle Irby, Chengan Du & Feng Li. (2017) Lipid–Drug Conjugate for Enhancing Drug Delivery. Molecular Pharmaceutics 14:5, pages 1325-1338.
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Ruben Vardanyan. 2017. Piperidine-Based Drug Discovery. Piperidine-Based Drug Discovery 241 267 .
Edward Kim, Christoph U. Correll, Lian Mao, H. Lynn Starr & Larry Alphs. (2016) Once-monthly paliperidone palmitate compared with conventional and atypical daily oral antipsychotic treatment in patients with schizophrenia. CNS Spectrums 21:6, pages 466-477.
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A. Bogomolova, L. Kaberov, O. Sedlacek, S.K. Filippov, P. Stepanek, V. Král, X.Y. Wang, S.L. Liu, X.D. Ye & M. Hruby. (2016) Double stimuli-responsive polymer systems: How to use crosstalk between pH- and thermosensitivity for drug depots. European Polymer Journal 84, pages 54-64.
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Annika Tuomela, Jukka Saarinen, Clare J. Strachan, Jouni Hirvonen & Leena Peltonen. (2016) Production, applications and in vivo fate of drug nanocrystals. Journal of Drug Delivery Science and Technology 34, pages 21-31.
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Atul P. Sherje & Vaishali Londhe. (2015) Ternary Inclusion Complex of Paliperidone with β-Cyclodextrin and Hydrophilic Polymer for Solubility and Dissolution Enhancement. Journal of Pharmaceutical Innovation 10:4, pages 324-334.
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Nerea Palomares, Ana Montes, Marina Díaz-Marsá & José L. Carrasco. (2015) Effectiveness of long-acting paliperidone palmitate in borderline personality disorder. International Clinical Psychopharmacology 30:6, pages 338-341.
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Kadir Demirci, Süleyman Keleş, Arif Demirdaş & Cafer Çağrı Korucu. (2015) Manic Symptoms during a Switch from Paliperidone ER to Paliperidone Palmitate in a Patient with Schizophrenia. Case Reports in Psychiatry 2015, pages 1-3.
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Madaswamy S Muthu, Poornima Agrawal & Rahul Pratap Singh. (2014) Antipsychotic nanomedicine: a successful platform for clinical use. Nanomedicine 9:14, pages 2071-2074.
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Wanlop Atsariyasing & Morris Goldman. 2014. Schizophrenia. Schizophrenia 225 262 .
Paraskevi Nikolaidou, Marinos Chatzopoulos, Dionysis Seretis & Albert Michael. (2018) Paliperidone – a costly option for schizophrenia. The Psychiatrist 37:9, pages 308-309.
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Eun Ji Park, Sarmila Amatya, Myung Sun Kim, Jong Hoon Park, Eunyoung Seol, Heeyong Lee, Young-Hee Shin & Dong Hee Na. (2013) Long-acting injectable formulations of antipsychotic drugs for the treatment of schizophrenia. Archives of Pharmacal Research 36:6, pages 651-659.
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Rahul ManchandaPierre ChueAshok MallaPhil TibboMarc-André RoyRichard WilliamsSrividya IyerDanyael LutgensNicola Banks. (2017) Long-Acting Injectable Antipsychotics: Evidence of Effectiveness and Use. The Canadian Journal of Psychiatry 58:5_suppl, pages 5-13.
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