Advanced search
Publication Cover
Expert Review of Vaccines Volume 11, 2012 - Issue 6
Submit an article Journal homepage
825
Views
95
CrossRef citations to date
0
Altmetric
Review

Liposomes containing lipid A: an effective, safe, generic adjuvant system for synthetic vaccines

Carl R Alving Laboratory of Adjuvant and Antigen Research, US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA. [email protected]
,
Mangala Rao Laboratory of Adjuvant and Antigen Research, US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA
,
Nicholas J Steers Laboratory of Adjuvant and Antigen Research, US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA
,
Gary R Matyas Laboratory of Adjuvant and Antigen Research, US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA
&
Alexander V Mayorov Laboratory of Adjuvant and Antigen Research, US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA
Pages 733-744 | Published online: 09 Jan 2014

Citations (95)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Shiqi Zhou, Yuan Luo & Jonathan F. Lovell. (2023) Vaccine approaches for antigen capture by liposomes. Expert Review of Vaccines 22:1, pages 1022-1040.
Read now
Yarong Zeng, Feihong Zou, Ningshao Xia & Shaowei Li. (2023) In-depth review of delivery carriers associated with vaccine adjuvants: current status and future perspectives. Expert Review of Vaccines 22:1, pages 681-695.
Read now
Tamara Aghebati, Mahdieh Arabsalmani, Amir Hooshang Mohammadpour, Mohammad Afshar, Mahmoud Reza Jaafari, Khalil Abnous, Saeed Nazemi & Ali Badiee. (2020) Development of an effective liposomal cholesterol ester transfer protein (CETP) vaccine for protecting against atherosclerosis in rabbit model. Pharmaceutical Development and Technology 25:4, pages 432-439.
Read now
Carl R. Alving, Kristina K. Peachman, Gary R. Matyas, Mangala Rao & Zoltan Beck. (2020) Army Liposome Formulation (ALF) family of vaccine adjuvants. Expert Review of Vaccines 19:3, pages 279-292.
Read now
Xueting Wang, Ning Wang, Ning Li, Yuanyuan Zhen & Ting Wang. (2016) Multifunctional particle-constituted microneedle arrays as cutaneous or mucosal vaccine adjuvant-delivery systems. Human Vaccines & Immunotherapeutics 12:8, pages 2075-2089.
Read now
Carl R. Alving, Zoltan Beck, Gary R. Matyas & Mangala Rao. (2016) Liposomal adjuvants for human vaccines. Expert Opinion on Drug Delivery 13:6, pages 807-816.
Read now

Articles from other publishers (89)

Jonathan F. Lovell, Kazutoyo Miura, Yeong Ok Baik, Chankyu Lee, Jeong-Yoon Lee, Young-Shin Park, Ingi Hong, Jung Hyuk Lee, Taewoo Kim, Sang Hwan Seo, Jae-Ouk Kim, Manki Song, Chung-Jong Kim, Jae-Ki Choi, Jieun Kim, Eun Ju Choo & Jung-Hyun Choi. (2024) One-year antibody durability induced by EuCorVac-19, a liposome-displayed COVID-19 receptor binding domain subunit vaccine, in healthy Korean subjects. International Journal of Infectious Diseases 138, pages 73-80.
Crossref
Edurne Rujas, Beatriz Apellániz, Johana Torralba, David Andreu, Jose M.M. Caaveiro, Shixia Wang, Shan Lu & Jose L. Nieva. (2024) Liposome-based peptide vaccines to elicit immune responses against the membrane active domains of the HIV-1 Env glycoprotein. Biochimica et Biophysica Acta (BBA) - Biomembranes 1866:1, pages 184235.
Crossref
Dhruv N. Desai, Ahmed Mahal, Rajat Varshney, Ahmad J. Obaidullah, Bhawna Gupta, Pratikhya Mohanty, Priyabrata Pattnaik, Nrusingha Charan Mohapatra, Snehasish Mishra, Venkataramana Kandi, Ali A. Rabaan & Ranjan K. Mohapatra. (2023) Nanoadjuvants: Promising Bioinspired and Biomimetic Approaches in Vaccine Innovation. ACS Omega 8:31, pages 27953-27968.
Crossref
Valeria Castelletto, Jani Seitsonen & Ian W. Hamley. (2023) Effect of Glycosylation on Self-Assembly of Lipid A Lipopolysaccharides in Aqueous Solutions. Langmuir 39:24, pages 8516-8522.
Crossref
Huanyu Li, Xiaoyu Sun, Yanyun Zhao, Changzhu Zhang, Kai Jiang, Jie Ren, Lijuan Xing & Miao He. (2023) Pan-cancer analysis of TASL: a novel immune infiltration-related biomarker for tumor prognosis and immunotherapy response prediction. BMC Cancer 23:1.
Crossref
Zhen Wang, Aizhen Zhao, Chenhui Wang, Danyang Huang, Jing Yu, Letong Yu, Yuanming Wu & Xiaoyuan Wang. (2023) Metabolic engineering of Escherichia coli to efficiently produce monophosphoryl lipid A . Biotechnology and Applied Biochemistry 70:3, pages 1332-1345.
Crossref
Carl R. Alving, Mangala Rao & Gary R. Matyas. (2023) Similarities and differences of chemical compositions and physical and functional properties of adjuvant system 01 and army liposome formulation with QS21. Frontiers in Immunology 14.
Crossref
Hemanga Hazarika, Harshita Krishnatreyya, Bedanta Bhattacharjee, Damanbhalang Rynjah, Dharmajit Gogoi, Abdul Baquee Ahmed & Kamaruz Zaman. 2023. Malarial Drug Delivery Systems. Malarial Drug Delivery Systems 161 185 .
Yang Bo & Hua Wang. (2022) Materials‐based vaccines for infectious diseases. WIREs Nanomedicine and Nanobiotechnology 14:5.
Crossref
Shuenn-Jue Wu, Dan Ewing, Appavu K. Sundaram, Hua-Wei Chen, Zhaodong Liang, Ying Cheng, Vihasi Jani, Peifang Sun, Gregory D. Gromowski, Rafael A. De La Barrera, Megan A. Schilling, Nikolai Petrovsky, Kevin R. Porter & Maya Williams. (2022) Enhanced Immunogenicity of Inactivated Dengue Vaccines by Novel Polysaccharide-Based Adjuvants in Mice. Microorganisms 10:5, pages 1034.
Crossref
Edouard Alphandéry. (2022) Nano dimensions/adjuvants in COVID-19 vaccines. Journal of Materials Chemistry B 10:10, pages 1520-1552.
Crossref
D. S. Tretiakova & E. L. Vodovozova. (2022) Liposomes as Adjuvants and Vaccine Delivery Systems. Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology 16:1, pages 1-20.
Crossref
Alexander Tishchenko, Vladimir Terekhov, Nikolay Pimenov & Regina Ivannikova. (2022) Prevention of enterotoxigenic escherichiosis as a way to stabilize the ecological situation of anthropogenic pollution by antibiotic-resistant strains. IOP Conference Series: Earth and Environmental Science 981:4, pages 042067.
Crossref
Moustafa T. Mabrouk, Kevin ChiemEdurne Rujas, Wei-Chiao HuangDushyant Jahagirdar, Breandan Quinn, Meera Surendran Nair, Ruth H. Nissly, Victoria S. CavenerNina R. Boyle, Ty A. Sornberger, Suresh V. Kuchipudi, Joaquin OrtegaJean-Philippe Julien, Luis Martinez-Sobrido & Jonathan Lovell. (2021) Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice. Science Advances 7:49.
Crossref
Qiuting Chen, Nan Wu, Yuhui Gao, Xiaojun Wang, Jie Wu & Guanghui Ma. (2021) Alum Pickering Emulsion as Effective Adjuvant to Improve Malaria Vaccine Efficacy. Vaccines 9:11, pages 1244.
Crossref
Pooria Nakhaei, Ria Margiana, Dmitry O. Bokov, Walid Kamal Abdelbasset, Mohammad Amin Jadidi Kouhbanani, Rajender S. Varma, Faroogh Marofi, Mostafa Jarahian & Nasrin Beheshtkhoo. (2021) Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol. Frontiers in Bioengineering and Biotechnology 9.
Crossref
Kwinten Sliepen, Edith Schermer, Ilja Bontjer, Judith A. Burger, Réka Felfödiné Lévai, Philipp Mundsperger, Philip J. M. Brouwer, Monica Tolazzi, Attila Farsang, Dietmar Katinger, John P. Moore, Gabriella Scarlatti, Robin J. Shattock, Quentin J. Sattentau & Rogier W. Sanders. (2021) Interplay of diverse adjuvants and nanoparticle presentation of native-like HIV-1 envelope trimers. npj Vaccines 6:1.
Crossref
Patrick B. Memvanga & Christian I. Nkanga. (2021) Liposomes for malaria management: the evolution from 1980 to 2020. Malaria Journal 20:1.
Crossref
David Nardo, Caleb M. Akers, Nicholas E. Cheung, Cierra M. Isom, Jason T. Spaude, Daniel W. Pack & Vincent J. Venditto. (2021) Cyanuric chloride as the basis for compositionally diverse lipids. RSC Advances 11:40, pages 24752-24761.
Crossref
Clara J. Sei, Mangala Rao, Richard F. Schuman, Luke T. Daum, Gary R. Matyas, Nimisha Rikhi, Kevin Muema, Alexander Anderson, Ousman Jobe, Kellie A. Kroscher, Carl R. Alving & Gerald W. Fischer. (2021) Conserved Influenza Hemagglutinin, Neuraminidase and Matrix Peptides Adjuvanted with ALFQ Induce Broadly Neutralizing Antibodies. Vaccines 9:7, pages 698.
Crossref
Maria Montoya & Elma Z. Tchilian. 2021. Veterinary Vaccines. Veterinary Vaccines 11 23 .
Saed Abbasi & Satoshi Uchida. (2021) Multifunctional Immunoadjuvants for Use in Minimalist Nucleic Acid Vaccines. Pharmaceutics 13:5, pages 644.
Crossref
Jasmin Federizon, Conrard Giresse Tetsassi Feugmo, Wei-Chiao Huang, Xuedan He, Kazutoyo Miura, Aida Razi, Joaquin Ortega, Mikko Karttunen & Jonathan F. Lovell. (2021) Experimental and Computational Observations of Immunogenic Cobalt Porphyrin Lipid Bilayers: Nanodomain-Enhanced Antigen Association. Pharmaceutics 13:1, pages 98.
Crossref
Sahra Bashiri, Prashamsa Koirala, Istvan Toth & Mariusz Skwarczynski. (2020) Carbohydrate Immune Adjuvants in Subunit Vaccines. Pharmaceutics 12:10, pages 965.
Crossref
Ruoyu Cheng, Flavia Fontana, Junyuan Xiao, Zehua Liu, Patrícia Figueiredo, Mohammad-Ali Shahbazi, Shiqi Wang, Jing Jin, Giulia Torrieri, Jouni T. Hirvonen, Hongbo Zhang, Tongtong Chen, Wenguo Cui, Yong Lu & Hélder A. Santos. (2020) Recombination Monophosphoryl Lipid A-Derived Vacosome for the Development of Preventive Cancer Vaccines. ACS Applied Materials & Interfaces 12:40, pages 44554-44562.
Crossref
Johana Torralba, Igor de la Arada, Pablo Carravilla, Sara Insausti, Edurne Rujas, Eneko Largo, Christian EggelingJosé L. R. Arrondo, Beatriz Apellániz & José L. Nieva. (2020) Cholesterol Constrains the Antigenic Configuration of the Membrane-Proximal Neutralizing HIV-1 Epitope. ACS Infectious Diseases 6:8, pages 2155-2168.
Crossref
Pushpendra Singh, Gary R. Matyas, Alexander Anderson & Zoltan Beck. (2020) Biophysical characterization of polydisperse liposomal adjuvant formulations. Biochemical and Biophysical Research Communications 529:2, pages 362-365.
Crossref
Hyo‐Jung Park, Eun‐Kyoung Bang, Jung Joo Hong, Sang‐Myeong Lee, Hae Li Ko, Hye Won Kwak, Hyelim Park, Kyung Won Kang, Rhoon‐Ho Kim, Seung Rok Ryu, Green Kim, Hanseul Oh, Hye‐Jung Kim, Kyuri Lee, Minjeong Kim, Soo Young Kim, Jae‐Ouk Kim, Karim El‐Baz, Hyukjin Lee, Manki Song, Dae Gwin Jeong, Gyochang Keum & Jae‐Hwan Nam. (2020) Nanoformulated Single‐Stranded RNA‐Based Adjuvant with a Coordinative Amphiphile as an Effective Stabilizer: Inducing Humoral Immune Response by Activation of Antigen‐Presenting Cells. Angewandte Chemie International Edition 59:28, pages 11540-11549.
Crossref
Hyo‐Jung Park, Eun‐Kyoung Bang, Jung Joo Hong, Sang‐Myeong Lee, Hae Li Ko, Hye Won Kwak, Hyelim Park, Kyung Won Kang, Rhoon‐Ho Kim, Seung Rok Ryu, Green Kim, Hanseul Oh, Hye‐Jung Kim, Kyuri Lee, Minjeong Kim, Soo Young Kim, Jae‐Ouk Kim, Karim El‐Baz, Hyukjin Lee, Manki Song, Dae Gwin Jeong, Gyochang Keum & Jae‐Hwan Nam. (2020) Nanoformulated Single‐Stranded RNA‐Based Adjuvant with a Coordinative Amphiphile as an Effective Stabilizer: Inducing Humoral Immune Response by Activation of Antigen‐Presenting Cells. Angewandte Chemie 132:28, pages 11637-11646.
Crossref
William Wheat, Lyndah Chow, Vanessa Rozo, Julia Herman, Kelly Still Brooks, Aimee Colbath, Randy Hunter & Steven Dow. (2020) Non-specific protection from respiratory tract infections in cattle generated by intranasal administration of an innate immune stimulant. PLOS ONE 15:6, pages e0235422.
Crossref
Collin T. Inglut, Aaron J. Sorrin, Thilinie Kuruppu, Shruti Vig, Julia Cicalo, Haroon Ahmad & Huang-Chiao Huang. (2020) Immunological and Toxicological Considerations for the Design of Liposomes. Nanomaterials 10:2, pages 190.
Crossref
Justin R. Adams, Sujata Senapati, Shannon L. Haughney, Michael J. Wannemuehler, Balaji Narasimhan & Surya K. Mallapragada. (2019) Safety and biocompatibility of injectable vaccine adjuvants composed of thermogelling block copolymer gels. Journal of Biomedical Materials Research Part A 107:8, pages 1754-1762.
Crossref
Binbin Zheng, Jiaojiao Xu, Gaoxian Chen, Sihang Zhang, Zeyu Xiao & Wei Lu. (2019) Bacterium‐Mimicking Vector with Enhanced Adjuvanticity for Cancer Immunotherapy and Minimized Toxicity. Advanced Functional Materials 29:33, pages 1901437.
Crossref
Pushpendra Singh, Jeffrey Bodycomb, Bill Travers, Kuba Tatarkiewicz, Sean Travers, Gary R. Matyas & Zoltan Beck. (2019) Particle size analyses of polydisperse liposome formulations with a novel multispectral advanced nanoparticle tracking technology. International Journal of Pharmaceutics 566, pages 680-686.
Crossref
Dagmar Hildebrand, Camila Metz-Zumaran, Greta Jaschkowitz & Klaus Heeg. (2019) Silencing SOCS1 via Liposome-Packed siRNA Sustains TLR4-Ligand Adjuvant. Frontiers in Immunology 10.
Crossref
Ning Wang, Minnan Chen & Ting Wang. (2019) Liposomes used as a vaccine adjuvant-delivery system: From basics to clinical immunization. Journal of Controlled Release 303, pages 130-150.
Crossref
Dunwan Zhu, Chunyan Hu, Fan Fan, Yu Qin, Chenlu Huang, Zhiming Zhang, Lu Lu, Hai Wang, Hongfan Sun, Xigang Leng, Chun Wang, Deling Kong & Linhua Zhang. (2019) Co-delivery of antigen and dual agonists by programmed mannose-targeted cationic lipid-hybrid polymersomes for enhanced vaccination. Biomaterials 206, pages 25-40.
Crossref
Diego A. Espinosa, P. Robert Beatty, Gabrielle L. Reiner, Kelsey E. Sivick, Laura Hix Glickman, Thomas W. DubenskyJr.Jr. & Eva Harris. (2019) Cyclic Dinucleotide–Adjuvanted Dengue Virus Nonstructural Protein 1 Induces Protective Antibody and T Cell Responses. The Journal of Immunology 202:4, pages 1153-1162.
Crossref
Lien Lybaert, Karim Vermaelen, Bruno G. De Geest & Lutz Nuhn. (2018) Immunoengineering through cancer vaccines – A personalized and multi-step vaccine approach towards precise cancer immunity. Journal of Controlled Release 289, pages 125-145.
Crossref
Marc J. Braunstein, John Kucharczyk & Sylvia Adams. (2018) Targeting Toll-Like Receptors for Cancer Therapy. Targeted Oncology 13:5, pages 583-598.
Crossref
Marc Baay, Kaatje Bollaerts & Thomas Verstraeten. (2018) A systematic review and meta-analysis on the safety of newly adjuvanted vaccines among older adults. Vaccine 36:29, pages 4207-4214.
Crossref
Sunita Minz & Ravi Shankar Pandey. (2018) Development of Adjuvanted Solid Fat Nanoemulsions for Pulmonary Hepatitis B Vaccination. Journal of Pharmaceutical Sciences 107:6, pages 1701-1712.
Crossref
Zoltan Beck, Oscar B. Torres, Gary R. Matyas, David E. Lanar & Carl R. Alving. (2018) Immune response to antigen adsorbed to aluminum hydroxide particles: Effects of co-adsorption of ALF or ALFQ adjuvant to the aluminum-antigen complex. Journal of Controlled Release 275, pages 12-19.
Crossref
Roberto Nisini, Noemi Poerio, Sabrina Mariotti, Federica De Santis & Maurizio Fraziano. (2018) The Multirole of Liposomes in Therapy and Prevention of Infectious Diseases. Frontiers in Immunology 9.
Crossref
Agnieszka Sulima, Rashmi Jalah, Joshua F. G. Antoline, Oscar B. Torres, Gregory H. Imler, Jeffrey R. Deschamps, Zoltan Beck, Carl R. Alving, Arthur E. Jacobson, Kenner C. Rice & Gary R. Matyas. (2017) A Stable Heroin Analogue That Can Serve as a Vaccine Hapten to Induce Antibodies That Block the Effects of Heroin and Its Metabolites in Rodents and That Cross-React Immunologically with Related Drugs of Abuse. Journal of Medicinal Chemistry 61:1, pages 329-343.
Crossref
Jerrold Weiss & Jason Barker. (2018) Diverse pro-inflammatory endotoxin recognition systems of mammalian innate immunity. F1000Research 7, pages 516.
Crossref
Tianshu Li & Shinji Takeoka. 2018. Smart Nanoparticles for Biomedicine. Smart Nanoparticles for Biomedicine 31 47 .
Pengxia Song, Shenyi He, Aihua Zhou, Gang Lv, Jingjing Guo, Jian Zhou, Yali Han, Huaiyu Zhou, Zhen Hao & Hua Cong. (2017) Vaccination with toxofilin DNA in combination with an alum-monophosphoryl lipid A mixed adjuvant induces significant protective immunity against Toxoplasma gondii. BMC Infectious Diseases 17:1.
Crossref
Ruijing Liang, Jun Xie, Jun Li, Ke Wang, Liping Liu, Yujie Gao, Mubashir Hussain, Guanxin Shen, Jintao Zhu & Juan Tao. (2017) Liposomes-coated gold nanocages with antigens and adjuvants targeted delivery to dendritic cells for enhancing antitumor immune response. Biomaterials 149, pages 41-50.
Crossref
Rein Verbeke, Ine Lentacker, Laura Wayteck, Karine Breckpot, Mieke Van Bockstal, Benedicte Descamps, Christian Vanhove, Stefaan C. De Smedt & Heleen Dewitte. (2017) Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy: Restoring the immunogenicity of immunosilent mRNA. Journal of Controlled Release 266, pages 287-300.
Crossref
Zheng Liu & Jun Guo. (2017) NKT-cell glycolipid agonist as adjuvant in synthetic vaccine. Carbohydrate Research 452, pages 78-90.
Crossref
Atefeh Razazan, Javad Behravan, Atefeh Arab, Nastaran Barati, Leila Arabi, Zahra Gholizadeh, Mahdi Hatamipour, Amin Reza Nikpoor, Amir Abbas Momtazi-Borojeni, Fatemeh Mosaffa, Mohamad Hosein Ghahremani & Mahmoud Reza Jaafari. (2017) Conjugated nanoliposome with the HER2/neu-derived peptide GP2 as an effective vaccine against breast cancer in mice xenograft model. PLOS ONE 12:10, pages e0185099.
Crossref
Jun Xie, Chaohua Yang, Qianqian Liu, Jun Li, Ruijing Liang, Chen Shen, Yi Zhang, Ke Wang, Liping Liu, Khurram Shezad, Martin Sullivan, Yong Xu, Guanxin Shen, Juan Tao, Jintao Zhu & Zhiping Zhang. (2017) Encapsulation of Hydrophilic and Hydrophobic Peptides into Hollow Mesoporous Silica Nanoparticles for Enhancement of Antitumor Immune Response. Small 13:40, pages 1701741.
Crossref
Kamal El Bissati, Ying Zhou, Sara Maria Paulillo, Senthil Kumar Raman, Christopher P. Karch, Craig W. Roberts, David E. Lanar, Steve Reed, Chris Fox, Darrick Carter, Jeff Alexander, Alessandro Sette, John Sidney, Hernan Lorenzi, Ian J. Begeman, Peter Burkhard & Rima McLeod. (2017) Protein nanovaccine confers robust immunity against Toxoplasma. npj Vaccines 2:1.
Crossref
Oscar B. Torres, Gary R. Matyas, Mangala Rao, Kristina K. Peachman, Rashmi Jalah, Zoltan Beck, Nelson L. Michael, Kenner C. Rice, Arthur E. Jacobson & Carl R. Alving. (2017) Heroin-HIV-1 (H2) vaccine: induction of dual immunologic effects with a heroin hapten-conjugate and an HIV-1 envelope V2 peptide with liposomal lipid A as an adjuvant. npj Vaccines 2:1.
Crossref
Eiji Yuba, Ayaka Yamaguchi, Yuta Yoshizaki, Atsushi Harada & Kenji Kono. (2017) Bioactive polysaccharide-based pH-sensitive polymers for cytoplasmic delivery of antigen and activation of antigen-specific immunity. Biomaterials 120, pages 32-45.
Crossref
Valerie P. O'brien, Thomas J. Hannan, Hailyn V. Nielsen & Scott J. Hultgren. 2017. Urinary Tract Infections. Urinary Tract Infections 589 646 .
Ning Wang, Yuanyuan Zhen, Yiguang Jin, Xueting Wang, Ning Li, Shaohong Jiang & Ting Wang. (2017) Combining different types of multifunctional liposomes loaded with ammonium bicarbonate to fabricate microneedle arrays as a vaginal mucosal vaccine adjuvant-dual delivery system (VADDS). Journal of Controlled Release 246, pages 12-29.
Crossref
C.B. Fox, D. Carter, R.M. Kramer, A.M. Beckmann & S.G. Reed. 2017. Immunopotentiators in Modern Vaccines. Immunopotentiators in Modern Vaccines 105 127 .
Mangala Rao & Carl R. Alving. (2016) Adjuvants for HIV vaccines. Current Opinion in HIV and AIDS 11:6, pages 585-592.
Crossref
Erik Őrfi & János Szebeni. (2016) The immune system of the gut and potential adverse effects of oral nanocarriers on its function. Advanced Drug Delivery Reviews 106, pages 402-409.
Crossref
Ying Liu & Chunying Chen. (2016) Role of nanotechnology in HIV/AIDS vaccine development. Advanced Drug Delivery Reviews 103, pages 76-89.
Crossref
Eiji Yuba. (2016) Design of pH-sensitive polymer-modified liposomes for antigen delivery and their application in cancer immunotherapy. Polymer Journal 48:7, pages 761-771.
Crossref
Ramesh AkkinaAtef AllamAlejandro B. BalazsJoel N. BlanksonJohn C. BurnettSofia CasaresJ. Victor GarciaKim J. HasenkrugFatah KashanchiScott G. KitchenFlorian KleinPriti KumarAndrew D. LusterLarisa Y. PoluektovaMangala RaoBrigitte E. Sanders-BeerLeonard D. ShultzJerome A. Zack. (2016) Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary. AIDS Research and Human Retroviruses 32:2, pages 109-119.
Crossref
Jorgen Stassijns, Kaatje Bollaerts, Marc Baay & Thomas Verstraeten. (2016) A systematic review and meta-analysis on the safety of newly adjuvanted vaccines among children. Vaccine 34:6, pages 714-722.
Crossref
Valerie P. O’Brien, Thomas J. Hannan, Hailyn V. Nielsen & Scott J. Hultgren. (2016) Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections. Microbiology Spectrum 4:1.
Crossref
Matthias GieseMatthias Giese. 2016. Introduction to Molecular Vaccinology. Introduction to Molecular Vaccinology 165 198 .
Oscar B. Torres, Carl R. Alving, Arthur E. Jacobson, Kenner C. Rice & Gary R. Matyas. 2016. Biologics to Treat Substance Use Disorders. Biologics to Treat Substance Use Disorders 397 424 .
Ning Wang & Ting Wang. 2016. Vaccine Design. Vaccine Design 635 649 .
Zoltan Beck, Gary R. Matyas, Rashmi Jalah, Mangala Rao, Victoria R. Polonis & Carl R. Alving. (2015) Differential immune responses to HIV-1 envelope protein induced by liposomal adjuvant formulations containing monophosphoryl lipid A with or without QS21. Vaccine 33:42, pages 5578-5587.
Crossref
Yuanyuan Zhen, Ning Wang, Zibin Gao, Xiaoyu Ma, Biao Wei, Yihui Deng & Ting Wang. (2015) Multifunctional liposomes constituting microneedles induced robust systemic and mucosal immunoresponses against the loaded antigens via oral mucosal vaccination. Vaccine 33:35, pages 4330-4340.
Crossref
Yuchen Fan, Preety Sahdev, Lukasz J. Ochyl, Jonathan J. Akerberg & James J. Moon. (2015) Cationic liposome–hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens. Journal of Controlled Release 208, pages 121-129.
Crossref
Beatriz Apellániz, Edurne Rujas, Soraya Serrano, Koldo Morante, Kouhei Tsumoto, Jose M.M. Caaveiro, M. Ángeles Jiménez & José L. Nieva. (2015) The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region. Journal of Biological Chemistry 290:21, pages 12999-13015.
Crossref
Zoltan Beck, Gary R. Matyas & Carl R. Alving. (2015) Detection of liposomal cholesterol and monophosphoryl lipid A by QS-21 saponin and Limulus polyphemus amebocyte lysate. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848:3, pages 775-780.
Crossref
Melissa C. Hanson, Wuhbet Abraham, Monica P. Crespo, Stephanie H. Chen, Haipeng Liu, Greg Lee Szeto, Mikyung Kim, Ellis L. Reinherz & Darrell J. Irvine. (2015) Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides. Vaccine 33:7, pages 861-868.
Crossref
Beatriz Apellániz & José L. Nieva. 2015. Peptide and Protein Vaccines. Peptide and Protein Vaccines 15 54 .
Reto A. Schwendener. (2014) Liposomes as vaccine delivery systems: a review of the recent advances. Therapeutic Advances in Vaccines 2:6, pages 159-182.
Crossref
Carl R. Alving, Gary R. Matyas, Oscar Torres, Rashmi Jalah & Zoltan Beck. (2014) Adjuvants for vaccines to drugs of abuse and addiction. Vaccine 32:42, pages 5382-5389.
Crossref
Ning Wang, Ting Wang, Meiling Zhang, Ruonan Chen, Ruowen Niu & Yihui Deng. (2014) Mannose derivative and lipid A dually decorated cationic liposomes as an effective cold chain free oral mucosal vaccine adjuvant-delivery system. European Journal of Pharmaceutics and Biopharmaceutics 88:1, pages 194-206.
Crossref
Kacee H. Sims, Ewan M. Tytler, John Tipton, Kasey L. Hill, Stephen W. Burgess & Walter A. Shaw. (2014) Avanti lipid tools: Connecting lipids, technology, and cell biology. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1841:8, pages 1038-1048.
Crossref
Soraya Serrano, Aitziber Araujo, Beatriz Apellániz, Steve Bryson, Pablo Carravilla, Igor de la Arada, Nerea Huarte, Edurne Rujas, Emil F. Pai, José L.R. Arrondo, Carmen Domene, María Angeles Jiménez & José L. Nieva. (2014) Structure and Immunogenicity of a Peptide Vaccine, Including the Complete HIV-1 gp41 2F5 Epitope. Journal of Biological Chemistry 289:10, pages 6565-6580.
Crossref
Gary R. Matyas, Kenner C. Rice, Kejun Cheng, Fuying Li, Joshua F.G. Antoline, Malliga R. Iyer, Arthur E. Jacobson, Alexander V. Mayorov, Zoltan Beck, Oscar B. Torres & Carl R. Alving. (2014) Facial recognition of heroin vaccine opiates: Type 1 cross-reactivities of antibodies induced by hydrolytically stable haptenic surrogates of heroin, 6-acetylmorphine, and morphine. Vaccine 32:13, pages 1473-1479.
Crossref
Harshad P. Patil, Senthil Murugappan, Wouter ter Veer, Tjarko Meijerhof, Aalzen de Haan, Henderik W. Frijlink, Jan Wilschut, Wouter L.J. Hinrichs & Anke Huckriede. (2014) Evaluation of monophosphoryl lipid A as adjuvant for pulmonary delivered influenza vaccine. Journal of Controlled Release 174, pages 51-62.
Crossref
Jaroslav Turánek, Josef Mašek, Michal Křupka & Milan Raška. 2014. Molecular Vaccines. Molecular Vaccines 561 577 .
Mark T. Orr, Christopher B. Fox, Susan L. Baldwin, Sandra J. Sivananthan, Elyse Lucas, Susan Lin, Tony Phan, James J. Moon, Thomas S. Vedvick, Steven G. Reed & Rhea N. Coler. (2013) Adjuvant formulation structure and composition are critical for the development of an effective vaccine against tuberculosis. Journal of Controlled Release 172:1, pages 190-200.
Crossref
Shruti Chopra, Natarajan Venkatesan & Guru V. Betageri. (2013) Liposomes as nanocarriers for anti-HIV therapy. Drug Delivery and Translational Research 3:5, pages 471-478.
Crossref
Shannon L. Haughney, Latrisha K. Petersen, Amy D. Schoofs, Amanda E. Ramer-Tait, Janice D. King, David E. Briles, Michael J. Wannemuehler & Balaji Narasimhan. (2013) Retention of structure, antigenicity, and biological function of pneumococcal surface protein A (PspA) released from polyanhydride nanoparticles. Acta Biomaterialia 9:9, pages 8262-8271.
Crossref
Gary R. Matyas, Alexander V. Mayorov, Kenner C. Rice, Arthur E. Jacobson, Kejun Cheng, Malliga R. Iyer, Fuying Li, Zoltan Beck, Kim D. Janda & Carl R. Alving. (2013) Liposomes containing monophosphoryl lipid A: A potent adjuvant system for inducing antibodies to heroin hapten analogs. Vaccine 31:26, pages 2804-2810.
Crossref
Jonathan W. Lockner, Sam On Ho, Karen C. McCague, Su Ming Chiang, Thai Q. Do, Gary Fujii & Kim D. Janda. (2013) Enhancing nicotine vaccine immunogenicity with liposomes. Bioorganic & Medicinal Chemistry Letters 23:4, pages 975-978.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.