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Original Research

Operationalizing a frailty index using routine blood and urine tests

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Pages 1029-1040 | Published online: 28 Jun 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Samuel Schülein, Cornel Christian Sieber, Karl-Günter Gaßmann & Martin Ritt. (2020) Frail Older Individuals Maintaining a Steady Standing Position: Associations Between Sway Measurements with Frailty Status Across Four Different Frailty Instruments. Clinical Interventions in Aging 15, pages 451-467.
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Yuting Wang, Rui Zhang, Yanjiao Shen, Lin Su, Birong Dong & Qiukui Hao. (2019) Prediction of chemotherapy adverse reactions and mortality in older patients with primary lung cancer through frailty index based on routine laboratory data. Clinical Interventions in Aging 14, pages 1187-1197.
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Jakob Jäger, Cornel Christian Sieber, Karl-Günter Gaßmann & Martin Ritt. (2019) Changes of a frailty index based on common blood and urine tests during a hospital stay on geriatric wards predict 6-month and 1-year mortality in older people. Clinical Interventions in Aging 14, pages 473-484.
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Teng Ma, Jian Cai, Yin-Sheng Zhu, Xue-Feng Chu, Yong Wang, Guo-Ping Shi, Zheng-Dong Wang, Shun Yao, Xiao-Feng Wang & Xiao-Yan Jiang. (2018) Association between a frailty index based on common laboratory tests and QTc prolongation in older adults: the Rugao Longevity and Ageing Study. Clinical Interventions in Aging 13, pages 797-804.
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Articles from other publishers (33)

Faisal F. Hakeem, Asri Maharani, Chris Todd & Terence W O'Neill. (2023) Development, validation and performance of laboratory frailty indices: A scoping review. Archives of Gerontology and Geriatrics 111, pages 104995.
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Elisa Heikkilä, Marika Salminen, Anna Viljanen, Taina Katajamäki, Marja-Kaisa Koivula, Kari Pulkki, Raimo Isoaho, Sirkka-Liisa Kivelä, Matti Viitanen, Minna Löppönen, Tero Vahlberg, Mikko S. Venäläinen, Laura L. Elo, Laura Viikari & Kerttu Irjala. (2023) A novel easy-to-use index to predict institutionalization and death in older population – a 10-year population-based follow-up study. BMC Geriatrics 23:1.
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Natasha Melo Resendes, A. Chada, A. Torres-Morales, M. Fernandez, A. Diaz-Quiñones, C. Gomez, S. Oomrigar, L. Burton & J. G. Ruiz. (2023) Association between a Frailty Index from Common Laboratory Values and Vital Signs (FI-LAB) and Hospital and Post-Hospital Outcomes in Veterans with COVID-19 Infection. The journal of nutrition, health & aging.
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Kai Wang, Quan She, Min Li, Hongye Zhao, Weihong Zhao, Bo Chen & Jianqing Wu. (2023) Prognostic significance of frailty status in patients with primary lung cancer. BMC Geriatrics 23:1.
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David G Sapp, Brianna M Cormier, Kenneth Rockwood, Susan E Howlett & Stefan S Heinze. (2023) The frailty index based on laboratory test data as a tool to investigate the impact of frailty on health outcomes: a systematic review and meta-analysis. Age and Ageing 52:1.
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Lena Schulte-Kemna, David Kühne, Lukas Bettac, Hannes Herrmann, Ulla Ludwig, Martin Kächele & Bernd Schröppel. (2022) Therapieansprechen und Komplikationen von älteren Patienten mit ANCA(antineutrophile cytoplasmatische Antikörper)-assoziierten VaskulitidenTreatment response and complications of older patients with ANCA(antineutrophil cytoplasmatic antibody)-associated vasculitis. Zeitschrift für Gerontologie und Geriatrie.
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Weimin Bai, Benchuan Hao, Lijun Xu, Ji Qin, Weihao Xu & Lijie Qin. (2022) Frailty index based on laboratory tests improves prediction of short-and long-term mortality in patients with critical acute myocardial infarction. Frontiers in Medicine 9.
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Otoniel Ysea‐Hill, Christian J. Gomez, Natalie Mansour, Kamal Wahab, Mihn Hoang, Mabel Labrada & Jorge G. Ruiz. (2022) The association of a frailty index from laboratory tests and vital signs with clinical outcomes in hospitalized older adults. Journal of the American Geriatrics Society 70:11, pages 3163-3175.
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Olivia Reid, Janet Ngo, Samanta Lalic, Elizabeth Su & Rohan A. Elliott. (2022) Paracetamol dosing in hospital and on discharge for older people who are frail or have low body weight. British Journal of Clinical Pharmacology 88:10, pages 4565-4572.
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Chunxiu Wang, Xianghua Fang, Zhe Tang, Yang Hua, Zhongying Zhang, Xiang Gu, Beibei Liu & Xunming Ji. (2022) A frailty index based on routine laboratory data predicts increased risk of mortality in Chinese community-dwelling adults aged over 55 years: a five-year prospective study. BMC Geriatrics 22:1.
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Sha Huang, Yan Wang, Lanlan Chen & Xiaoyan Chen. (2022) Use of a frailty index based upon routine laboratory data to predict complication and mortality in older community-acquired pneumonia patients. Archives of Gerontology and Geriatrics 101, pages 104692.
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Yoonjoo Kim, Kijun Song, Chang Moo Kang & Hyangkyu Lee. (2022) Impact of preoperative laboratory frailty index on mortality and clinical outcomes in older surgical patients with cancer. Scientific Reports 12:1.
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Joanna M Blodgett, Mario U Pérez-Zepeda, Judith Godin, D Scott Kehler, Melissa K Andrew, Susan Kirkland, Kenneth Rockwood & Olga Theou. (2022) Frailty indices based on self-report, blood-based biomarkers and examination-based data in the Canadian Longitudinal Study on Aging. Age and Ageing 51:5.
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Deborah Lekan, Thomas P. McCoy, Marjorie Jenkins, Somya Mohanty & Prashanti Manda. (2021) Frailty and In-Hospital Mortality Risk Using EHR Nursing Data. Biological Research For Nursing 24:2, pages 186-201.
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Lihuan Guan, Cheng Hwee Soh, Esmee M. Reijnierse, Wen Kwang Lim & Andrea B. Maier. (2022) Association of a modified laboratory frailty index with adverse outcomes in geriatric rehabilitation inpatients: RESORT. Mechanisms of Ageing and Development 203, pages 111648.
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Arum Lim, JiYeon Choi, Hyunju Ji & Hyangkyu Lee. (2022) Frailty assessment using routine clinical data: An integrative review. Archives of Gerontology and Geriatrics 99, pages 104612.
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Marta Kałużna-Oleksy, Agata Kukfisz, Jacek Migaj, Magdalena Dudek, Helena Krysztofiak, Filip Sawczak, Magdalena Szczechla, Katarzyna Przytarska, Ewa Straburzyńska-Migaj, Marta Wleklik & Izabella Uchmanowicz. (2021) A Simple Risk Score Based on Routine Clinical Parameters Can Predict Frailty in Hospitalized Heart Failure Patients. Journal of Clinical Medicine 10:24, pages 5963.
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Elisa Heikkilä, Marika Salminen, Anna Viljanen, Taina Katajamäki, Marja-Kaisa Koivula, Kari Pulkki, Raimo Isoaho, Sirkka-Liisa Kivelä, Matti Viitanen, Minna Löppönen, Tero Vahlberg, Laura Viikari & Kerttu Irjala. (2021) A practical laboratory index to predict institutionalization and mortality – an 18-year population-based follow-up study. BMC Geriatrics 21:1.
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Neil G. Docherty, Christian Delles, Patrick D’Haese, Anita T. Layton, Carlos Martínez-Salgado, Benjamin A. Vervaet & Francisco J. López-Hernández. (2021) Haemodynamic frailty – A risk factor for acute kidney injury in the elderly. Ageing Research Reviews 70, pages 101408.
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Xi Jin, Yue Ren, Li Shao, Zengqing Guo, Chang Wang, Ying He, Lan Zhou, Minghua Cong, Hu Ma, Wei Wang, Chunling Zhou, Yongdong Feng, Yi Ba, Jianguo Gao, Miaomiao Lu, Mengmeng Zhang, Xue‐wei Gu, Chunhua Song, Hongxia Xu & Hanping Shi. (2021) Prevalence of frailty and prediction of mortality in Chinese cancer patients using a frailty index‐based clinical algorithm—A multicentre study. Cancer Medicine 10:18, pages 6207-6217.
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O. N. Tkacheva, Yu. V. Kotovskaya, A. S. Mil'to, N. K. Runihina, E. V. Frolova, A. V. Naumov, E. N. Dudinskaya, L. V. Matchekhina, N. M. Vorobyeva, A. V. Rozanov, V. S. Ostapenko, E. A. Mkhitaryan, N. V. Sharashkina, N. O. Khovasova, E. A. TyukhmenevI. V. Babenko, O. M. Lesnyak, K. Yu. Belova, L. P. Evstigneeva & O. B. Ershova. (2021) Falls in older and senile patients. Clinical giudelines. Russian Journal of Geriatric Medicine:2, pages 153-185.
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Jaclyn Kapilow, Junho Ahn, Kathryn Gallaway & Megan Sorich. (2021) Early Outcomes After Surgical Management of Geriatric Patella Fractures. Geriatric Orthopaedic Surgery & Rehabilitation 12, pages 215145932098769.
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O. N. Tkacheva, Yu. V. Kotovskaya, N. K. Runikhina, E. V. Frolova, A. V. Naumov, N. M. Vorobyeva, V. S. Ostapenko, E. A. Mkhitaryan, N. V. Sharashkina, E. A. Tyukhmenev, A. P. Pereverzev & E. N. Dudinskaya. (2020) Clinical guidelines frailty. Part 2. Russian Journal of Geriatric Medicine:2, pages 115-130.
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O. N. Tkacheva, Yu. V. Kotovskaya, N. K. Runikhina, E. V. Frolova, A. V. Naumov, N. M. Vorobyeva, V. S. Ostapenko, E. A. Mkhitaryan, N. V. Sharashkina, E. A. Tyukhmenev, A. P. Pereverzev & E. N. Dudinskaya. (2020) Clinical guidelines on frailty. Russian Journal of Geriatric Medicine:1, pages 11-46.
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D.S. Kehler, O. Theou & K. Rockwood. (2019) Bed rest and accelerated aging in relation to the musculoskeletal and cardiovascular systems and frailty biomarkers: A review. Experimental Gerontology 124, pages 110643.
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Lea Becker, Dorothee Volkert, Cornel Christian Sieber, Karl-Günter Gaßmann & Martin Ritt. (2019) Predictability of a modified Mini- Nutritional- Assessment version on six-month and one-year mortality in hospitalized geriatric patients: a comparative analysis. Scientific Reports 9:1.
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Kenneth Rockwood & Susan E. Howlett. (2019) Age-related deficit accumulation and the diseases of ageing. Mechanisms of Ageing and Development 180, pages 107-116.
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Joanna M. Blodgett, Olga Theou, Arnold Mitnitski, Susan E. Howlett & Kenneth Rockwood. (2019) Associations between a laboratory frailty index and adverse health outcomes across age and sex. AGING MEDICINE 2:1, pages 11-17.
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Qiukui Hao, Xuelian Sun, Ming Yang, Biao Dong, Birong Dong & Yuquan Wei. (2019) Prediction of mortality in Chinese very old people through the frailty index based on routine laboratory data. Scientific Reports 9:1.
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Kali S Thomas, Jessica A Ogarek, Joan M Teno, Pedro L Gozalo & Vincent Mor. (2019) Development and Validation of the Nursing Home Minimum Data Set 3.0 Mortality Risk Score (MRS3). The Journals of Gerontology: Series A 74:2, pages 219-225.
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Kevin Thomas, Ka Hin Wong, Susan C. Steelman & Analiz Rodriguez. (2019) Surgical Risk Assessment and Prevention in Elderly Spinal Deformity Patients. Geriatric Orthopaedic Surgery & Rehabilitation 10, pages 215145931985168.
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Ming Yang, Yan Zhuo, Xiaoyi Hu & Lingling Xie. (2018) Predictive validity of two frailty tools for mortality in Chinese nursing home residents: frailty index based on common laboratory tests (FI-Lab) versus FRAIL-NH. Aging Clinical and Experimental Research 30:12, pages 1445-1452.
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Ghalib A. Bello, Roberto G. Lucchini, Susan L. Teitelbaum, Moshe Shapiro, Michael A. Crane & Andrew C. Todd. (2018) Development of a Physiological Frailty Index for the World Trade Center General Responder Cohort. Current Gerontology and Geriatrics Research 2018, pages 1-12.
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