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Original Research

Point-of-care procalcitonin test to reduce antibiotic exposure in patients hospitalized with acute exacerbation of COPD

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Pages 1381-1389 | Published online: 22 Jun 2016

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Read on this site (7)

Dina Elnajdy & Faris El-Dahiyat. (2022) Antibiotics duration guided by biomarkers in hospitalized adult patients; a systematic review and meta-analysis. Infectious Diseases 54:6, pages 387-402.
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Mihaela S. Stefan, Kerry A. Spitzer, Sehar Zulfiqar, Brent D. Heineman, Timothy P. Hogan, Lauren M. Westafer, Michael S. Pulia, Victor M. Pinto-Plata & Peter K. Lindenauer. (2022) Uncertainty as a critical determinant of antibiotic prescribing in patients with an asthma exacerbation: a qualitative study. Journal of Asthma 59:2, pages 352-361.
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Wentao Ni, Jing Bao, Donghong Yang, Wen Xi, Keqiang Wang, Yu Xu, Rongbao Zhang & Zhancheng Gao. (2019) Potential of serum procalcitonin in predicting bacterial exacerbation and guiding antibiotic administration in severe COPD exacerbations: a systematic review and meta-analysis. Infectious Diseases 51:9, pages 639-650.
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Philipp Schuetz, Rebekka Bolliger, Meret Merker, Mirjam Christ-Crain, Daiana Stolz, Michael Tamm, Charles E Luyt, Michel Wolff, Stefan Schroeder, Vandack Nobre, Konrad Reinhart, Angela Branche, Pierre Damas, Maarten Nijsten, Rodrigo O. Deliberato, Alessia Verduri, Bianca Beghé, Bin Cao, Yahya Shehabi, Jens-Ulrik S. Jensen, Albertus Beishuizen, Evelien de Jong, Matthias Briel, Tobias Welte & Beat Mueller. (2018) Procalcitonin-guided antibiotic therapy algorithms for different types of acute respiratory infections based on previous trials. Expert Review of Anti-infective Therapy 16:7, pages 555-564.
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David MG Halpin, Marc Miravitlles, Norbert Metzdorf & Bartolomé Celli. (2017) Impact and prevention of severe exacerbations of COPD: a review of the evidence. International Journal of Chronic Obstructive Pulmonary Disease 12, pages 2891-2908.
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Aiyuan Zhou, Zijing Zhou, Yiyang Zhao & Ping Chen. (2017) The recent advances of phenotypes in acute exacerbations of COPD. International Journal of Chronic Obstructive Pulmonary Disease 12, pages 1009-1018.
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Mario Cazzola, Paola Rogliani, Stefano Aliberti, Francesco Blasi & Maria Gabriella Matera. (2017) An update on the pharmacotherapeutic management of lower respiratory tract infections. Expert Opinion on Pharmacotherapy 18:10, pages 973-988.
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Articles from other publishers (31)

Alexander Jordan, Pradeesh Sivapalan, Valdemar Rømer & Jens-Ulrik Jensen. (2023) Time-Updated Phenotypic Guidance of Corticosteroids and Antibiotics in COPD: Rationale, Perspective and a Proposed Method. Biomedicines 11:5, pages 1395.
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Allison B Chambliss, Khushbu Patel, Jessica M Colón-Franco, Joshua Hayden, Sophie E Katz, Emi Minejima & Alison Woodworth. (2023) AACC Guidance Document on the Clinical Use of Procalcitonin. The Journal of Applied Laboratory Medicine 8:3, pages 598-634.
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Wan Fadzlina Wan Muhd Shukeri, Mohd Basri Mat-Nor, Azrina MD Ralib, Mohd Zulfakar Mazlan & Mohd Hasyizan Hassan. (2022) Point-of-Care Procalcitonin to Guide the Discontinuation of Antibiotic Treatment in the Intensive Care Unit: A Malaysian Randomised Controlled Trial. Malaysian Journal of Medicine and Health Sciences 18:6, pages 65-71.
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Pelin Uysal. 2022. Biomarkers in Medicine. Biomarkers in Medicine 425 439 .
Evdoxia Kyriazopoulou & Evangelos J. Giamarellos-Bourboulis. (2022) Antimicrobial Stewardship Using Biomarkers: Accumulating Evidence for the Critically Ill. Antibiotics 11:3, pages 367.
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Pradeesh Sivapalan & Jens-Ulrik Jensen. (2022) Biomarkers in Chronic Obstructive Pulmonary Disease: Emerging Roles of Eosinophils and Procalcitonin. Journal of Innate Immunity 14:2, pages 89-97.
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Cédric Daubin, François Fournel, Fabrice Thiollière, Fabrice Daviaud, Michel Ramakers, Andréa Polito, Bernard Flocard, Xavier Valette, Damien Du Cheyron, Nicolas Terzi, Muriel Fartoukh, Stephane Allouche & Jean-Jacques Parienti. (2021) Ability of procalcitonin to distinguish between bacterial and nonbacterial infection in severe acute exacerbation of chronic obstructive pulmonary syndrome in the ICU. Annals of Intensive Care 11:1.
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Shih-Lung Cheng, Ching-Hsiung Lin, Kuo-An Chu, Kuo-Liang Chiu, Sheng-Hao Lin, Horng-Chyuan Lin, Hsin-Kuo Ko, Yung-Che Chen, Chia-Hung Chen, Chau-Chyun Sheu, Wei-Chang Huang, Tsung-Ming Yang, Yu-Feng Wei, Jung-Yien Chien, Hao-Chien Wang & Meng-Chih Lin. (2021) Update on guidelines for the treatment of COPD in Taiwan using evidence and GRADE system-based recommendations. Journal of the Formosan Medical Association 120:10, pages 1821-1844.
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Jiaqi Di, Xuanlin Li, Yang Xie, Shuguang Yang & Xueqing Yu. (2021) Procalcitonin‐guided antibiotic therapy in AECOPD patients: Overview of systematic reviews. The Clinical Respiratory Journal 15:6, pages 579-594.
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Ahmed Yousuf, Hamish McAuley, Omer Elneima & Christopher E Brightling. (2021) The different phenotypes of COPD. British Medical Bulletin 137:1, pages 82-97.
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Pradeesh Sivapalan, Barbara Bonnesen & Jens-Ulrik Jensen. (2020) Novel Perspectives Regarding the Pathology, Inflammation, and Biomarkers of Acute Respiratory Distress Syndrome. International Journal of Molecular Sciences 22:1, pages 205.
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Ken Chen, Katherine A. Pleasants, Roy A. Pleasants, Tatsiana Beiko, Ronald G. Washburn, Zhiheng Yu, Suodi Zhai & M. Bradley Drummond. (2020) Procalcitonin for Antibiotic Prescription in Chronic Obstructive Pulmonary Disease Exacerbations: Systematic Review, Meta-Analysis, and Clinical Perspective. Pulmonary Therapy 6:2, pages 201-214.
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Diana Borre-Naranjo, Amilkar Almanza-Hurtado, Guillermo Ortiz-Ruiz & Carmelo Dueñas-Castell. (2020) Procalcitonina en el paciente crítico: ¿herramienta diagnóstica, guía intervención o marcador pronóstico?. Acta Colombiana de Cuidado Intensivo 20:4, pages 253-260.
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Andrew W. Creamer, Alice E. Kent & Maha Albur. (2019) Procalcitonin in respiratory disease: use as a biomarker for diagnosis and guiding antibiotic therapy. Breathe 15:4, pages 296-304.
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Kristina Vermeersch, Maria Gabrovska, Joseph Aumann, Ingel K. Demedts, Jean-Louis Corhay, Eric Marchand, Hans Slabbynck, Christel Haenebalcke, Michiel Haerens, Shane Hanon, Paul Jordens, Rudi Peché, Antoine Fremault, Tine Lauwerier, Anja Delporte, Bert Vandenberk, Rik Willems, Stephanie Everaerts, Ann Belmans, Kris Bogaerts, Geert M. Verleden, Thierry Troosters, Vincent Ninane, Guy G. Brusselle & Wim Janssens. (2019) Azithromycin during Acute Chronic Obstructive Pulmonary Disease Exacerbations Requiring Hospitalization (BACE). A Multicenter, Randomized, Double-Blind, Placebo-controlled Trial. American Journal of Respiratory and Critical Care Medicine 200:7, pages 857-868.
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Gregory L. Damhorst, Erika A. Tyburski, Oliver Brand, Greg S. Martin & Wilbur A. Lam. (2019) Diagnosis of acute serious illness: the role of point-of-care technologies. Current Opinion in Biomedical Engineering 11, pages 22-34.
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Daniel D. Murray, Theis Skovsgaard Itenov, Pradeesh Sivapalan, Josefin Viktoria Eklöf, Freja Stæhr Holm, Philipp Schuetz & Jens Ulrik Jensen. (2019) Biomarkers of Acute Lung Injury The Individualized Approach: for Phenotyping, Risk Stratification and Treatment Surveillance. Journal of Clinical Medicine 8:8, pages 1163.
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Zhuying Li, Xingxing Yuan, Ling Yu, Bingyu Wang, Fengli Gao & Jian Ma. (2019) Procalcitonin-guided antibiotic therapy in acute exacerbation of chronic obstructive pulmonary disease. Medicine 98:32, pages e16775.
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Jinxiang Wang & Bin Cao. (2019) Procalcitonin and other markers to guide antibiotic use in chronic obstructive pulmonary disease exacerbations in the era of antimicrobial resistance. Current Opinion in Pulmonary Medicine 25:2, pages 158-164.
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Hiang Ping Chan & Tow Keang Lim. (2019) Procalcitonin and antibiotics in moderate–severe acute exacerbation of chronic obstructive pulmonary disease. Current Opinion in Pulmonary Medicine 25:2, pages 150-157.
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Fiona Mendelson, Rulan Griesel, Nicki Tiffin, Molebogeng Rangaka, Andrew Boulle, Marc Mendelson & Gary Maartens. (2018) C-reactive protein and procalcitonin to discriminate between tuberculosis, Pneumocystis jirovecii pneumonia, and bacterial pneumonia in HIV-infected inpatients meeting WHO criteria for seriously ill: a prospective cohort study. BMC Infectious Diseases 18:1.
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Lotte SteutenJanne MewesIsabelle Lepage-NefkensHubertus Vrijhoef. (2018) Is Procalcitonin Biomarker-Guided Antibiotic Therapy a Cost-Effective Approach to Reduce Antibiotic Resistant and Clostridium difficile Infections in Hospitalized Patients? . OMICS: A Journal of Integrative Biology 22:9, pages 616-625.
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Elizabeth W. Covington, Megan Z. Roberts & Jenny Dong. (2018) Procalcitonin Monitoring as a Guide for Antimicrobial Therapy: A Review of Current Literature. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 38:5, pages 569-581.
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Cédric Daubin, Xavier Valette, Fabrice Thiollière, Jean-Paul Mira, Pascal Hazera, Djillali Annane, Vincent Labbe, Bernard Floccard, François Fournel, Nicolas Terzi, Damien Du Cheyron & Jean-Jacques Parienti. (2018) Procalcitonin algorithm to guide initial antibiotic therapy in acute exacerbations of COPD admitted to the ICU: a randomized multicenter study. Intensive Care Medicine 44:4, pages 428-437.
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Alex Pizzini, Wojciech Filipiak, Johannes Wille, Clemens Ager, Helmut Wiesenhofer, Róbert Kubinec, Jaroslav Blaško, Christoph Tschurtschenthaler, Chris A Mayhew, Günter Weiss & Rosa Bellmann-Weiler. (2018) Analysis of volatile organic compounds in the breath of patients with stable or acute exacerbation of chronic obstructive pulmonary disease. Journal of Breath Research 12:3, pages 036002.
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Philipp Schuetz, Yannick Wirz, Ramon Sager, Mirjam Christ-Crain, Daiana Stolz, Michael Tamm, Lila Bouadma, Charles E Luyt, Michel Wolff, Jean Chastre, Florence Tubach, Kristina B Kristoffersen, Olaf Burkhardt, Tobias Welte, Stefan Schroeder, Vandack Nobre, Long Wei, Heiner C Bucher, Djillali Annane, Konrad Reinhart, Ann R Falsey, Angela Branche, Pierre Damas, Maarten Nijsten, Dylan W de Lange, Rodrigo O Deliberato, Carolina F Oliveira, Vera Maravić-Stojković, Alessia Verduri, Bianca Beghé, Bin Cao, Yahya Shehabi, Jens-Ulrik S Jensen, Caspar Corti, Jos A H van Oers, Albertus Beishuizen, Armand R J Girbes, Evelien de Jong, Matthias Briel & Beat Mueller. (2018) Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis. The Lancet Infectious Diseases 18:1, pages 95-107.
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Dharani K. Narendra & Nicola A. Hanania. (2017) Procalcitonin in Chronic Obstructive Pulmonary Disease Exacerbations: Is It Ready for Primetime Use?. Annals of the American Thoracic Society 14:12, pages 1757-1758.
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Peter K. Lindenauer, Meng-Shiou Shieh, Mihaela S. Stefan, Kimberly A. Fisher, Sarah D. Haessler, Penelope S. Pekow, Michael B. Rothberg, Jerry A. Krishnan & Allan J. Walkey. (2017) Hospital Procalcitonin Testing and Antibiotic Treatment of Patients Admitted for Chronic Obstructive Pulmonary Disease Exacerbation. Annals of the American Thoracic Society 14:12, pages 1779-1785.
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Ramon Sager, Alexander Kutz, Beat Mueller & Philipp Schuetz. (2017) Procalcitonin-guided diagnosis and antibiotic stewardship revisited. BMC Medicine 15:1.
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Philipp Schuetz, Yannick Wirz, Ramon Sager, Mirjam Christ-Crain, Daiana Stolz, Michael Tamm, Lila Bouadma, Charles E Luyt, Michel Wolff, Jean Chastre, Florence Tubach, Kristina B Kristoffersen, Olaf Burkhardt, Tobias Welte, Stefan Schroeder, Vandack Nobre, Long Wei, Heiner C C Bucher, Neera Bhatnagar, Djillali Annane, Konrad Reinhart, Angela Branche, Pierre Damas, Maarten Nijsten, Dylan W de Lange, Rodrigo O Deliberato, Stella SS Lima, Vera Maravić-Stojković, Alessia Verduri, Bin Cao, Yahya Shehabi, Albertus Beishuizen, Jens-Ulrik S Jensen, Caspar Corti, Jos A Van Oers, Ann R Falsey, Evelien de Jong, Carolina F Oliveira, Bianca Beghe, Matthias Briel & Beat Mueller. (2017) Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. Cochrane Database of Systematic Reviews 2019:5.
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Alexander G. Mathioudakis, Victoria Chatzimavridou-Grigoriadou, Alexandru Corlateanu & Jørgen Vestbo. (2017) Procalcitonin to guide antibiotic administration in COPD exacerbations: a meta-analysis. European Respiratory Review 26:143, pages 160073.
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