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Original Research

Prescription of opioids for breathlessness in end-stage COPD: a national population-based study

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Pages 2651-2657 | Published online: 21 Oct 2016

Keep up to date with the latest research on this topic with citation updates for this article.

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Gabriella Eliason, Christer Janson, Gunnar Johansson, Kjell Larsson, Anders Lindén, Claes-Göran Löfdahl, Thomas Sandström & Josefin Sundh. (2023) Comorbid conditions as predictors of mortality in severe COPD – an eight-year follow-up cohort study. European Clinical Respiratory Journal 10:1.
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Cornelia A. Verberkt, Marieke H. J. van den Beuken-van Everdingen, Carmen D. Dirksen, Jos M. G. A. Schols, Lowie E. G. W. Vanfleteren, Frits M. E. Franssen, Miriam T. J. Groenen, Emiel F. M. Wouters & Daisy J. A. Janssen. (2021) Healthcare and Societal Costs in Patients with COPD and Breathlessness after Completion of a Comprehensive Rehabilitation Program. COPD: Journal of Chronic Obstructive Pulmonary Disease 18:2, pages 170-180.
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Natasha Smallwood, David Currow, Sara Booth, Anna Spathis, Louis Irving & Jennifer Philip. (2018) Differing Approaches to Managing the Chronic Breathlessness Syndrome in Advanced COPD: A Multi-National Survey of Specialists. COPD: Journal of Chronic Obstructive Pulmonary Disease 15:3, pages 294-302.
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Nicholas T Vozoris. (2017) The need for greater opioid pharmacovigilance in COPD. International Journal of Chronic Obstructive Pulmonary Disease 12, pages 189-192.
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Articles from other publishers (29)

Hans-Peter KapfhammerHans-Peter Kapfhammer. 2022. Depression, Angst, traumatischer Stress und internistische Erkrankungen. Depression, Angst, traumatischer Stress und internistische Erkrankungen 289 378 .
Marlies van Dijk, Kris J. M. Mooren, Jan-Willem K. van den Berg, Wendy J. C. van Beurden-Moeskops, Roxane Heller-Baan, Sander M. de Hosson, Wai Yee Lam-Wong, Liesbeth Peters, Karin Pool & Huib A. M. Kerstjens. (2021) Opioids in patients with COPD and refractory dyspnea: literature review and design of a multicenter double blind study of low dosed morphine and fentanyl (MoreFoRCOPD). BMC Pulmonary Medicine 21:1.
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Han-Yee Neo, Chun-Wei Yap, Liang-Ming Teo, Liang-Tee Lee, Hong-Weng Tan, Hui-Ying Xu, Allyn Hum & John A. Abisheganaden. (2021) Palliative Rehabilitation Improves Health Care Utilization and Function in Frail Older Adults with Chronic Lung Diseases. Journal of the American Medical Directors Association 22:12, pages 2478-2485.e1.
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Heidi Jerpseth, Ingrid R. Knutsen, Kari T. Jensen & Kristin Halvorsen. (2021) Mirror of shame: Patients experiences of late‐stage COPD. A qualitative study. Journal of Clinical Nursing 30:19-20, pages 2854-2862.
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Nicolas Roche. (2021) Systemic Medications in Chronic Obstructive Pulmonary Disease. Thoracic Surgery Clinics 31:2, pages 97-106.
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Thomas Moran, Dominica Zentner, James Wong, Jennifer Philip & Natasha Smallwood. (2021) Chronic breathlessness in advanced cardiorespiratory disease: patient perceptions of opioid use. BMJ Supportive & Palliative Care, pages bmjspcare-2020-002853.
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Jenny Genberg, Joanna M. Davies, Zainab Ahmadi, David Currow, Miriam J. Johnson, Hanan Tanash, Sabrina Bajwah & Magnus Ekström. (2021) Indications and patterns of use of benzodiazepines and opioids in severe interstitial lung disease: a population-based longitudinal study. ERJ Open Research 7:1, pages 00716-2020.
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Matthias Villalobos & Michael Kreuter. 2021. Palliative Care in Lung Disease. Palliative Care in Lung Disease 27 41 .
David Hui & Eduardo Bruera. (2020) Use of short-acting opioids in the management of breathlessness: an evidence-based review. Current Opinion in Supportive & Palliative Care 14:3, pages 167-176.
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Nicolas Roche. (2020) Systemic Medications in Chronic Obstructive Pulmonary Disease. Clinics in Chest Medicine 41:3, pages 485-494.
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Nicholas T. Vozoris, Priscila Pequeno, Ping Li, Peter C. Austin, Denis E. O'Donnell & Andrea S. Gershon. (2020) Predictors of Opioid-related Adverse Pulmonary Events among Older Adults with Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society 17:8, pages 965-973.
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David C. Currow, Miriam J. Johnson, Allan Pollack, Diana H. Ferreira, Slavica Kochovska, Magnus Ekström & Christopher Harrison. (2020) Breathlessness and opioid prescribing in COPD in general practice: a cross-sectional, observational study. ERJ Open Research 6:2, pages 00299-2019.
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Damien Viglino, Raoul Daoust, Sebastien Bailly, Caroline Faivre-Pierret, Isma Charif, Matthieu Roustit, Jean Paquet, Guillaume Debaty, Jean-Louis Pépin, Maxime Maignan & Jean-Marc Chauny. (2020) Opioid drug use in emergency and adverse outcomes among patients with chronic obstructive pulmonary disease: a multicenter observational study. Scientific Reports 10:1.
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Tham Thi Le, Siyeon Park, Michelle Choi, Marniker Wijesinha, Bilal Khokhar & Linda Simoni-Wastila. (2020) Respiratory events associated with concomitant opioid and sedative use among Medicare beneficiaries with chronic obstructive pulmonary disease. BMJ Open Respiratory Research 7:1, pages e000483.
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Jacques Baillargeon, Gurinder Singh, Yong-Fang Kuo, Mukaila A. Raji, Jordan Westra & Gulshan Sharma. (2019) Association of Opioid and Benzodiazepine Use with Adverse Respiratory Events in Older Adults with Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society 16:10, pages 1245-1251.
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Kathleen Mechler & John Liantonio. (2019) Palliative Care Approach to Chronic Diseases. Primary Care: Clinics in Office Practice 46:3, pages 415-432.
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Zainab Ahmadi, Jacob Sandberg, Aaron Shannon-Honson, Zac Vandersman, David C. Currow & Magnus Ekström. (2018) Is chronic breathlessness less recognised and treated compared with chronic pain? A case-based randomised controlled trial. European Respiratory Journal 52:3, pages 1800887.
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Nicholas T. Vozoris. (2018) Opioids, Chronic Obstructive Pulmonary Disease, and Hyperbole. Journal of Palliative Medicine 21:6, pages 745-745.
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Marcus Waskiw-Ford, Anne Wu, Amar Mainra, Noah Marchand, Abdullatif Alhuzaim, Jean Bourbeau, Benjamin M. Smith & Dennis Jensen. (2018) Effect of Inhaled Nebulized Furosemide (40 and 120 mg) on Breathlessness during Exercise in the Presence of External Thoracic Restriction in Healthy Men. Frontiers in Physiology 9.
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Natasha Smallwood, Michelle Thompson, Matthew Warrender-Sparkes, Peter Eastman, Brian Le, Louis Irving & Jennifer Philip. (2018) Integrated respiratory and palliative care may improve outcomes in advanced lung disease. ERJ Open Research 4:1, pages 00102-2017.
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Rachel Lewis. (2018) End-of-life care in non-malignant conditions. InnovAiT: Education and inspiration for general practice 11:1, pages 41-47.
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Sara J. Abdallah, Courtney Wilkinson-Maitland, Nathalie Saad, Pei Zhi Li, Benjamin M. Smith, Jean Bourbeau & Dennis Jensen. (2017) Effect of morphine on breathlessness and exercise endurance in advanced COPD: a randomised crossover trial. European Respiratory Journal 50:4, pages 1701235.
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Nicholas T. Vozoris, Xuesong Wang, Peter C. Austin, Douglas S. Lee, Anne L. Stephenson, Denis E. O’Donnell, Sudeep S. Gill & Paula A. Rochon. (2017) Adverse cardiac events associated with incident opioid drug use among older adults with COPD. European Journal of Clinical Pharmacology 73:10, pages 1287-1295.
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Matthew Maddocks, Natasha Lovell, Sara Booth, William D-C Man & Irene J Higginson. (2017) Palliative care and management of troublesome symptoms for people with chronic obstructive pulmonary disease. The Lancet 390:10098, pages 988-1002.
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David Currow, Gareth John Watts, Miriam Johnson, Christine F McDonald, John O Miners, Andrew A Somogyi, Linda Denehy, Nicola McCaffrey, Danny J Eckert, Philip McCloud, Sandra Louw, Lawrence Lam, Aine Greene, Belinda Fazekas, Katherine C Clark, Kwun Fong, Meera R Agar, Rohit Joshi, Sharon Kilbreath, Diana Ferreira & Magnus Ekström. (2017) A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study protocol. BMJ Open 7:7, pages e018100.
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Adelle S. Jee, Tamera J. Corte, Stephen J. Wort, Neil D. Eves, Claire E. Wainwright & Amanda Piper. (2017) Year in review 2016: Interstitial lung disease, pulmonary vascular disease, pulmonary function, paediatric lung disease, cystic fibrosis and sleep. Respirology 22:5, pages 1022-1034.
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Nicholas T. Vozoris. (2017) Prescription opioid use in advanced COPD: benefits, perils and controversies. European Respiratory Journal 49:6, pages 1700479.
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Nicholas T. Vozoris, Denis E. O'Donnell, Chaim Bell, Sudeep S. Gill & Paula A. Rochon. (2017) Incident opioid use is associated with risk of respiratory harm in non-palliative COPD. European Respiratory Journal 49:3, pages 1602529.
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Magnus Ekström, Sabrina Bajwah & Miriam J. Johnson. (2017) Incident opioid drug use and adverse respiratory outcomes among older adults with COPD. European Respiratory Journal 49:3, pages 1602311.
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