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International Journal of Chronic Obstructive Pulmonary Disease Volume 13, 2018 - Issue
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Original Research

Neutrophil to lymphocyte ratio is a better indicator of COPD exacerbation severity in neutrophilic endotypes than eosinophilic endotypes

Emine AksoyRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
,
Zuhal KarakurtRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]Correspondence[email protected]
,
Sinem GungorRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
,
Birsen OcakliRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
,
İpek OzmenRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
,
Elif YildirimRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
,
Eylem TuncayRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
,
Meltem Coban AgcaRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
,
Nezihe Ciftaslan GoksenogluRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
&
Nalan AdigüzelRespiratory Intensive Care Unit Clinic, Sureyyapasa Chest Diseases and Thoracic Surgery Teaching and Research Hospital, Istanbul, Turkey, [email protected]
 show all
Pages 2721-2730 | Published online: 04 Sep 2018

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Tzu-Tao Chen, Kang-Yun Lee, Jer-Hwa Chang, Chi-Li Chung, Huan Minh Tran, Amja Manullang, Shu-Chuan Ho, Kuan-Yuan Chen, Chien-Hua Tseng, Sheng-Ming Wu & Hsiao-Chi Chuang. (2023) Prediction value of neutrophil and eosinophil count at risk of COPD exacerbation. Annals of Medicine 55:2.
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Michal Mleko, Kazimierz Pitynski, Elzbieta Pluta, Aleksandra Czerw, Katarzyna Sygit, Beata Karakiewicz & Tomasz Banas. (2021) Role of Systemic Inflammatory Reaction in Female Genital Organ Malignancies – State of the Art. Cancer Management and Research 13, pages 5491-5508.
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Peter J. Barnes. (2021) Endo-phenotyping of COPD patients. Expert Review of Respiratory Medicine 15:1, pages 27-37.
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Giordana Gava, Alexa Núñez, Cristina Esquinas, Mikel Sarasate, Eduardo Loeb, Pietro Pirina, Marc Miravitlles & Miriam Barrecheguren. (2020) Analysis of Blood Biomarkers in Patients with Chronic Obstructive Pulmonary Disease (COPD) and with Asthma-COPD Overlap (ACO). COPD: Journal of Chronic Obstructive Pulmonary Disease 17:3, pages 306-310.
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Alexa Nuñez, Viviana Marras, Matevz Harlander, Evgeni Mekov, Cristina Esquinas, Matjaz Turel, David Lestan, Rosen Petkov, Nikolay Yanev, Pietro Pirina, Silvia Negri, Marc Miravitlles & Miriam Barrecheguren. (2020) Association Between Routine Blood Biomarkers and Clinical Phenotypes and Exacerbations in Chronic Obstructive Pulmonary Disease. International Journal of Chronic Obstructive Pulmonary Disease 15, pages 681-690.
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Ahmed Gouda El-Gazzar, Mohammed Hussein Kamel, Ola Kamal Mohammad Elbahnasy & Marwa El-Sayed El-Naggar. (2020) Prognostic value of platelet and neutrophil to lymphocyte ratio in COPD patients. Expert Review of Respiratory Medicine 14:1, pages 111-116.
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Articles from other publishers (8)

Weihong Qiu, Heng He, Bin Wang, Dongming Wang, Ge Mu, Tao Xu, Min Zhou, Zi Ye, Jixuan Ma & Weihong Chen. (2023) Short-term impacts of air pollution on the platelet-lymphocyte ratio and neutrophil-lymphocyte ratio among urban adults in China. Journal of Environmental Sciences 125, pages 101-111.
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Ching-Hsiung Lin, Yi-Rong Li, Pei Ru Lin, Bing-Yen Wang, Sheng-Hao Lin, Kuo-Yang Huang & Chew-Teng Kor. (2022) Blood monocyte levels predict the risk of acute exacerbations of chronic obstructive pulmonary disease: a retrospective case–control study. Scientific Reports 12:1.
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Alvar Agustí, Stephanie Christenson, MeiLan Han & Dave Singh. (2022) New Frontiers in Chronic Obstructive Pulmonary Disease: Where Are We Heading?. EMJ Respiratory, pages 2-10.
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Yu-Ping Chang, Yu-Mu Chen, Ya-Chun Chang, Shih-Feng Liu, Wen-Feng Fang, Tung-Ying Chao, Chao-Chien Wu, Huang-Chih Chang, Meng-Chih Lin & Yung-Che Chen. (2022) Association of baseline parameters with year 0 and year 1 acute exacerbations in male patients with chronic obstructive pulmonary disease. International Journal of Immunopathology and Pharmacology 36, pages 039463202210990.
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Muhammed EMİN & Aydın BALCI. (2021) Effects Of Age, Body Mass Index, Complete Blood Count Parameters, and Biochemical Parameters on Stable COPD PatientsStabil KOAH hastalarında yaş, vücut kitle indeksi, tam kan sayımı ve biyokimyasal parametrelerin etkileri. Journal of Contemporary Medicine 11:1, pages 7-11.
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Tao Liu, Zi-Jian Xiang, Xiao-Meng Hou, Jing-Jing Chai, Yan-Li Yang & Xiao-Tong Zhang. (2021) Blood eosinophil count-guided corticosteroid therapy and as a prognostic biomarker of exacerbations of chronic obstructive pulmonary disease: a systematic review and meta-analysis. Therapeutic Advances in Chronic Disease 12, pages 204062232110287.
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Lindong Yuan, Lili Li, Tong Yu, Ziyun Yang, Tingting Jiang, Qiuxia Ma, Jun Qi, Yan Shi & Peige Zhao. (2020) The correlational study about neutrophil-to-lymphocyte ratio and exercise tolerance of chronic obstructive pulmonary disease patients. Medicine 99:33, pages e21550.
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Peter J. Barnes. (2019) Inflammatory endotypes in COPD. Allergy.
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