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Review

Status of and strategies for improving adherence to COPD treatment

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Pages 1503-1515 | Published online: 10 Jul 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (14)

Miguel Turégano-Yedro, Eva Trillo-Calvo, Fernando Navarro i Ros, José David Maya-Viejo, Cruz González Villaescusa, Jose Maria Echave Sustaeta, Esperanza Doña & Bernardino Alcázar Navarrete. (2023) Inhaler Adherence in COPD: A Crucial Step Towards the Correct Treatment. International Journal of Chronic Obstructive Pulmonary Disease 18, pages 2887-2893.
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Patricia Muñoz-Villegas, Humberto Martínez-Bautista & Oscar Olvera-Montaño. (2023) Determinants of adherence to treatment in patients with ophthalmic conditions. Expert Review of Clinical Pharmacology 16:12, pages 1249-1259.
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Ingmar Bergs, Katja S Just, Annegret Müller, Julia C Stingl & Michael Dreher. (2022) Emergency Department Visits Due to Dyspnea: Association with Inhalation Therapy in COPD and Cases with Adverse Drug Reactions. International Journal of Chronic Obstructive Pulmonary Disease 17, pages 1827-1834.
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Fernando González-Torralba, Adolfo Baloira, Araceli Abad, Antonia Fuster, Juan Luis García-Rivero, Patricia García-Sidro, Eduardo Márquez-Martín, Marta Palop, Néstor Soler & José Luis Velasco. (2022) FIDEPOC: Consensus on Inspiratory Flow and Lung Deposition as Key Decision Factors in COPD Inhaled Therapy. International Journal of Chronic Obstructive Pulmonary Disease 17, pages 1005-1015.
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Rita Georges Nohra, Taghrid Chaaban, Hala Sacre, Pascale Salameh, Zeina Aoun Bacha, Beatrice Le Bon Chami, Fadi Abou Rizk, Paul Makhlouf & Monique Rothan-Tondeur. (2022) Evaluating the Feasibility and Pretesting the Impact of an Educational and Telemonitoring Program for COPD Patients in Lebanon. International Journal of Chronic Obstructive Pulmonary Disease 17, pages 949-965.
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Javier Martínez-Guiu, Ivan Arroyo-Fernández & Raül Rubio. (2022) Impact of patients’ attitudes and dynamics in needs and life experiences during their journey in COPD: an ethnographic study. Expert Review of Respiratory Medicine 16:1, pages 121-132.
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Yating Peng, Jiaxi Duan, Xin Li, Yuqin Zeng, Zijing Zhou, Minghua Deng, Ruoyun Ouyang, Yan Chen, Shan Cai & Ping Chen. (2021) Adherence to Inhaled Therapy in Patients with COPD Associated to Pneumoconiosis. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 2697-2706.
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Adolfo Baloira, Araceli Abad, Antonia Fuster, Juan Luis García Rivero, Patricia García-Sidro, Eduardo Márquez-Martín, Marta Palop, Néstor Soler, J L Velasco & Fernando González-Torralba. (2021) Lung Deposition and Inspiratory Flow Rate in Patients with Chronic Obstructive Pulmonary Disease Using Different Inhalation Devices: A Systematic Literature Review and Expert Opinion. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 1021-1033.
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Jean Bourbeau, Mona Bafadhel, Neil C Barnes, Chris Compton, Valentina Di Boscio, David A Lipson, Paul W Jones, Neil Martin, Gudrun Weiss & David M G Halpin. (2021) Benefit/Risk Profile of Single-Inhaler Triple Therapy in COPD. International Journal of Chronic Obstructive Pulmonary Disease 16, pages 499-517.
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Anne Tschacher, Cordula Cadus, Sebastian Schildge, Jens Peter Diedrich, Prashant N. Chhajed, Anne B. Leuppi-Taegtmeyer & Jörg Daniel Leuppi. (2021) Switching COPD patients from the disposable to the new reusable Respimat soft mist inhaler: a real-world study from Switzerland. Current Medical Research and Opinion 37:11, pages 2019-2033.
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Alessia Romagnoli, Fiorenzo Santoleri & Alberto Costantini. (2020) Adherence and persistence analysis after three years in real-life of inhalation therapies used in the treatment of COPD. Current Medical Research and Opinion 36:12, pages 2055-2061.
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Ruth Barlow, Ben Jones, Mike Rogerson, Hannah Bannister, Rebecca Stuart, Jawadh Iqbal, Leanne Andrews & Izzie Easton. (2020) An Evaluation of Service Provision and Novel Strength Assessment on Patient Outcomes in a UK-Based Pulmonary Rehabilitation Setting. COPD: Journal of Chronic Obstructive Pulmonary Disease 17:3, pages 280-288.
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Kaho Akimoto, Kuniaki Hirai, Tomohiro Matsunaga, Keisuke Kaneko, Hatsuko Mikuni, Tomoko Kawahara, Tomoki Uno, Akiko Fujiwara, Yoshito Miyata, Shin Ohta, Tetsuya Homma, Hideki Inoue, Fumihiro Yamaguchi, Sojiro Kusumoto, Shintaro Suzuki, Akihiko Tanaka & Hironori Sagara. (2020) The Relationship Between the “Adherence Starts with Knowledge-20” Questionnaire and Clinical Factors in Patients with COPD: A Multi-Center, Cross-Sectional Study. International Journal of Chronic Obstructive Pulmonary Disease 15, pages 3201-3211.
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Articles from other publishers (41)

Ning Xie, Zheng Zheng, Qilian Yang, Man Li & Xiaofen Ye. (2023) Nurses in China lack knowledge of inhaler devices: A cross-sectional study. Frontiers in Pharmacology 14.
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Ling Lin, Cong Liu, Wei Cheng, Qing Song, Yuqin Zeng, Xin Li, Dingding Deng, Dan Liu, Yan Chen, Shan Cai & Ping Chen. (2023) Comparison of treatment persistence, adherence, and risk of exacerbation in patients with COPD treated with single-inhaler versus multiple-inhaler triple therapy: A prospective observational study in China. Frontiers in Pharmacology 14.
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Li-Anne Audet, Mélanie Lavoie-Tremblay, Éric Tchouaket & Kelley Kilpatrick. (2023) The level of adherence to best-practice guidelines by interprofessional teams with and without acute care nurse practitioners in cardiac surgery: A study protocol. PLOS ONE 18:3, pages e0282467.
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Anna Katharina Mayr & Arschang Valipour. (2023) Modern Bronchoscopic Treatment Options for Patients with Chronic Bronchitis. Journal of Clinical Medicine 12:5, pages 1854.
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Beatrice Benatti, Nicolaja Girone, Dario Conti, Maddalena Cocchi, Francesco Achilli, Silvia Leo, Gianmarco Putti, Monica Bosi & Bernardo Dell’Osso. (2023) The Role of Lifestyle on Adherence to Treatment in a Sample of Patients with Unipolar and Bipolar Depression. International Journal of Environmental Research and Public Health 20:3, pages 1994.
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Seyed Iman Mirzadeh, Asiful Arefeen, Jessica Ardo, Ramin Fallahzadeh, Bryan Minor, Jung-Ah Lee, Janett A. Hildebrand, Diane Cook, Hassan Ghasemzadeh & Lorraine S. Evangelista. (2022) Use of machine learning to predict medication adherence in individuals at risk for atherosclerotic cardiovascular disease. Smart Health 26, pages 100328.
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Raja Dhar, Deepak Talwar, Prince James, Ashwini Mishra, Judo Vachaparambil, Saiprasad Patil, Nishtha Khatri, Sagar Bhagat & Hanmant Barkate. (2022) ICS/Ultra LABA in the Treatment of Obstructive Airway Diseases: A Consensus of Indian Experts. Advances in Respiratory Medicine 90:5, pages 407-424.
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Theresa R. Prosser & Suzanne G. Bollmeier. (2022) Concordance between reported medication taking behavior and prescription instructions for patients with chronic obstructive pulmonary disease visiting community pharmacies. Journal of the American Pharmacists Association 62:4, pages 1280-1286.
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Aizhamal Tabyshova, Talant Sooronbaev, Azamat Akylbekov, Maamed Mademilov, Aida Isakova, Aidai Erkinbaeva, Kamila Magdieva, Niels H. Chavannes, Maarten J. Postma & Job F. M. van Boven. (2022) Medication availability and economic barriers to adherence in asthma and COPD patients in low-resource settings. npj Primary Care Respiratory Medicine 32:1.
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Yingjian Yang, Wei Li, Yingwei Guo, Yang Liu, Qiang Li, Kai Yang, Shicong Wang, Nanrong Zeng, Wenxin Duan, Ziran Chen, Huai Chen, Xian Li, Wei Zhao, Rongchang Chen & Yan Kang. (2022) Early COPD Risk Decision for Adults Aged From 40 to 79 Years Based on Lung Radiomics Features. Frontiers in Medicine 9.
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Dominic P. Coppolo, Judy Schloss, Jason A. Suggett & Jolyon P. Mitchell. (2021) Non-Pharmaceutical Techniques for Obstructive Airway Clearance Focusing on the Role of Oscillating Positive Expiratory Pressure (OPEP): A Narrative Review. Pulmonary Therapy 8:1, pages 1-41.
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Daljeet Singh Dhanjal, Parvarish Sharma, Meenu Mehta, Murtaza M Tambuwala, Parteek Prasher, Keshav R Paudel, Gang Liu, Shakti D Shukla, Philip M Hansbro, Dinesh Kumar Chellappan, Kamal Dua & Saurabh Satija. (2022) Concepts of advanced therapeutic delivery systems for the management of remodeling and inflammation in airway diseases. Future Medicinal Chemistry 14:4, pages 271-288.
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Constança Monteiro, Tiago Maricoto, Filipe Prazeres, Pedro Augusto Simões & José Augusto Simões. (2022) Determining factors associated with inhaled therapy adherence on asthma and COPD: A systematic review and meta-analysis of the global literature. Respiratory Medicine 191, pages 106724.
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H. I. Shumko, T. V. Reva, V. O. Shuper, M. I. Shumko & V. P. Polataichuk. (2021) Influence of Clinical Anamnestic and Psychological Factors on Adherence to Treatment of Patients with Chronic Obstructive Pulmonary Disease. Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 6:6, pages 158-163.
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Boyuk Moradkhani, Samaneh Mollazadeh, Parastoo Niloofar, Afsaneh Bashiri & Mohammad Bagher Oghazian. (2021) Association between medication adherence and health-related quality of life in patients with chronic obstructive pulmonary disease. Journal of Pharmaceutical Health Care and Sciences 7:1.
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Monika Fekete, Vince Fazekas-Pongor, Peter Balazs, Stefano Tarantini, Anna N. Nemeth & Janos Tamas Varga. (2021) Role of new digital technologies and telemedicine in pulmonary rehabilitation. Wiener klinische Wochenschrift 133:21-22, pages 1201-1207.
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E. V. Bolotova, A. V. Dudnikova & L. V. Shulzhenko. (2021) Increased treatment adherence in patients with chronic obstructive pulmonary disease when using a fixed triple combination. Meditsinskiy sovet = Medical Council:16, pages 10-16.
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Tamara Alonso-Pérez, Elena García-Castillo & José Luis López-Campos. (2021) Escalando y desescalando el tratamiento en la enfermedad pulmonar obstructiva crónica. ¿El inhalador importa?. Archivos de Bronconeumología 57:9, pages 604-605.
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José Luis López-Campos, Myriam Calle Rubio, José Luis Izquierdo Alonso, Alberto Fernández-Villar, Beatriz Abascal-Bolado, Bernardino Alcázar, Francisco García-Río, Germán Peces-Barba, Joan Serra Batlles, José Javier Martínez Garcerán, Juan Antonio Riesco Miranda, Juan Marco Figueira-Gonçalves, Juan José Soler-Cataluña, Mikel Temprano, Francisco Ortega Ruiz, Salud Santos Pérez & Carlos José Álvarez Martínez. (2021) Consenso sobre el diagnóstico, tratamiento y seguimiento de la EPOC: Grupo de trabajo EPOC Forum. Archivos de Bronconeumología 57:9, pages 596-599.
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Tamara Alonso-Pérez, Elena García-Castillo & José Luis López-Campos. (2021) Escalation and de-escalation of therapy in chronic obstructive pulmonary disease. Is the inhaler important?. Archivos de Bronconeumología (English Edition) 57:9, pages 604-605.
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José Luis López-Campos, Myriam Calle Rubio, José Luis Izquierdo Alonso, Alberto Fernández-Villar, Beatriz Abascal-Bolado, Bernardino Alcázar, Francisco García-Río, Germán Peces-Barba, Joan Serra Batlles, José Javier Martínez Garcerán, Juan Antonio Riesco Miranda, Juan Marco Figueira-Gonçalves, Juan José Soler-Cataluña, Mikel Temprano, Francisco Ortega Ruiz, Salud Santos Pérez & Carlos José Álvarez Martínez. (2021) Forum COPD working group consensus on the diagnosis, treatment and follow-up of COPD. Archivos de Bronconeumología (English Edition) 57:9, pages 596-599.
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Joshua Holmes & Liam G. Heaney. (2021) Measuring adherence to therapy in airways disease. Breathe 17:2, pages 210037.
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Simona Maria Ţîrcă, Marius Sorin Ciontea, Elena Vlad & Florin Dumitru Mihălţan. (2021) Distant Compliance with Treatment in Patients with Chronic Respiratory Diseases: Asthma, Copd and Asthma-Copd Overlap Syndrome. Prospective Study. Internal Medicine 18:2, pages 15-47.
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Laura Carrasco Hernández, Candela Caballero Eraso, Borja Ruiz-Duque, María Abad Arranz, Eduardo Márquez Martín, Carmen Calero Acuña & Jose Luis Lopez-Campos. (2021) Predictors of Single Bronchodilation Treatment Response for COPD: An Observational Study with the Trace Database Cohort. Journal of Clinical Medicine 10:8, pages 1708.
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David M.G. Halpin, Sally Worsley, Afisi S. Ismaila, Kai-Michael Beeh, Dawn Midwinter, Janwillem W.H. Kocks, Elaine Irving, Jose M. Marin, Neil Martin, Maggie Tabberer, Neil G. Snowise & Chris Compton. (2021) INTREPID: single- versus multiple-inhaler triple therapy for COPD in usual clinical practice . ERJ Open Research 7:2, pages 00950-2020.
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Robert Janknegt, johan Kooistra, Esther Metting & Richard Dekhuijzen. (2021) Rational selection of inhalation devices in the treatment of chronic obstructive pulmonary disease by means of the System of Objectified Judgement Analysis (SOJA). European Journal of Hospital Pharmacy 28:2, pages e4-e4.
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Lindsay G S BengtsonTim BancroftCraig SchillingAmi R BuikemaRichard H Stanford. (2021) Development and validation of a drug adherence index for COPD. Journal of Managed Care & Specialty Pharmacy 27:2, pages 198-209.
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Michael Dreher, David Price, Asparuh Gardev, Pascale Peeters, Satish Arora, Simone van der Sar – van der Brugge, Richard Dekhuijzen & Omar S Usmani. (2021) Patient perceptions of the re-usable Respimat ® Soft Mist™ inhaler in current users and those switching to the device: A real-world, non-interventional COPD study . Chronic Respiratory Disease 18, pages 147997312098622.
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José-Luis Lopez-Campos, Borja Ruiz-Duque, Laura Carrasco-Hernandez & Candelaria Caballero-Eraso. (2021) Einbeziehung von Komorbiditäten und phänotypbasierter Medizin beim patientenzentrierten COPD-Management. Kompass Pneumologie 9:2, pages 60-67.
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Christian Taube, Valentina Bayer, Christoph Michael Zehendner & Arschang Valipour. (2020) Assessment of Patient Experiences with Respimat® in Everyday Clinical Practice. Pulmonary Therapy 6:2, pages 371-380.
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Carlo Baggio, Jalene V. Velazquez, Marco Fragai, Tara M. Nordgren & Maurizio Pellecchia. (2020) Therapeutic Targeting of MMP-12 for the Treatment of Chronic Obstructive Pulmonary Disease. Journal of Medicinal Chemistry 63:21, pages 12911-12920.
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Malin Axelsson, Benita Björk, Ulrika Berg & Karin Persson. (2020) Effect of an Educational Program on Healthcare Professionals’ Readiness to Support Patients with Asthma, Allergies, and Chronic Obstructive Lung Disease for Improved Medication Adherence. Nursing Research and Practice 2020, pages 1-11.
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José Luis Lopez-Campos, Borja Ruiz-Duque, Laura Carrasco-Hernandez & Candelaria Caballero-Eraso. (2020) Integrating Comorbidities and Phenotype-Based Medicine in Patient-Centered Medicine in COPD. Journal of Clinical Medicine 9:9, pages 2745.
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Ruxandra-Mioara Rajnoveanu, Armand-Gabriel Rajnoveanu, Andreea-Bianca Ardelean, Doina Adina Todea, Carmen-Monica Pop, Sabina Antonela Antoniu, Nicoleta Stefania Motoc, Ana Florica Chis, Ariadna Petronela Fildan & Milena Adina Man. (2020) Pulmonologists Adherence to the Chronic Obstructive Pulmonary Disease GOLD Guidelines: A Goal to Improve. Medicina 56:9, pages 422.
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Joël Ladner, Mahinour El Badrawy, Anas Nofal, Joseph Saba & Etienne Audureau. (2020) A cohort study of medication adherence among patients with chronic obstructive pulmonary disease in Egypt. npj Primary Care Respiratory Medicine 30:1.
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Hyun Jung Noh, Su Hyun Kim & Woo Joung Joung. (2020) Disease Awareness and Treatment Experience of Patients with Chronic Obstructive Pulmonary Disease. Journal of Korean Academy of Fundamentals of Nursing 27:2, pages 188-197.
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Ichraf Anane, Fatma Guezguez, Hend Knaz & Helmi Ben Saad. (2020) How to Stage Airflow Limitation in Stable Chronic Obstructive Pulmonary Disease Male Patients?. American Journal of Men's Health 14:3, pages 155798832092263.
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José Luis López-Campos, Laura Carrasco-Hernández, Lucas Román Rodríguez, Esther Quintana-Gallego, Carmen Carmona Bernal & Bernardino Alcázar Navarrete. (2020) Implicaciones clínicas del uso de la triple terapia en combinación de dosis fija en EPOC: del ensayo al paciente. Archivos de Bronconeumología 56:4, pages 242-248.
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José Luis López-Campos, Laura Carrasco-Hernández, Lucas Román Rodríguez, Esther Quintana-Gallego, Carmen Carmona Bernal & Bernardino Alcázar Navarrete. (2020) The clinical implications of triple therapy in fixed-dose combination in COPD: from the trial to the patient. Archivos de Bronconeumología (English Edition) 56:4, pages 242-248.
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Manuela Latorre, Giulia Parri & Pierluigi Paggiaro. (2020) Is adherence to treatment influenced by the ability to use inhaled devices in patients with COPD correctly?. Pulmonology 26:2, pages 63-65.
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Sana Aissa, Asma Knaz, Jihene Maatoug, Ahmed Khedher, Wafa Benzarti, Ahmed Abdelghani, Abdelhamid Garrouche, Abdelaziz Hayouni, Mohamed Benzarti, Imen Gargouri & Helmi Ben Saad. (2020) Adherence of North-African Pulmonologists to the 2017-Global Initiative for Chronic Obstructive Lung Disease (GOLD) Pharmacological Treatment Guidelines (PTGs) of Stable Chronic Obstructive Pulmonary Disease (COPD). BioMed Research International 2020, pages 1-12.
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