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Review

Current and novel drug therapies for idiopathic pulmonary fibrosis

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Pages 261-272 | Published online: 26 Sep 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Jun Fukihara & Yasuhiro Kondoh. (2016) Nintedanib (OFEV) in the treatment of idiopathic pulmonary fibrosis. Expert Review of Respiratory Medicine 10:12, pages 1247-1254.
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Jinqing Hu, Dewei Shang, Xinwen Xu, Xiuling He, Xiaojia Ni, Ming Zhang, Zhanzhang Wang, Chang Qiu, Shuhua Deng, Haoyang Lu, Xiuqing Zhu, Wencan Huang & Yuguan Wen. (2016) Effect of grapefruit juice and food on the pharmacokinetics of pirfenidone in healthy Chinese volunteers: a diet–drug interaction study. Xenobiotica 46:6, pages 516-521.
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David N O’Dwyer, Michelle E Armstrong, Minesh Kooblall & Seamas C Donnelly. (2015) Targeting defective Toll-like receptor-3 function and idiopathic pulmonary fibrosis. Expert Opinion on Therapeutic Targets 19:4, pages 507-514.
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James D. Williamson, Laura R. Sadofsky & Simon P. Hart. (2015) The pathogenesis of bleomycin-induced lung injury in animals and its applicability to human idiopathic pulmonary fibrosis. Experimental Lung Research 41:2, pages 57-73.
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Venerino Poletti, Claudia Ravaglia & Sara Tomassetti. (2014) Pirfenidone for the treatment of idiopathic pulmonary fibrosis. Expert Review of Respiratory Medicine 8:5, pages 539-545.
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Sushmita Chakraborty, Puneet Chopra, Senthil V Ambi, Sunanda G Dastidar & Abhijit Ray. (2014) Emerging therapeutic interventions for idiopathic pulmonary fibrosis. Expert Opinion on Investigational Drugs 23:7, pages 893-910.
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Yanfei Shen, Wanru Cai, Shu Lei & Zhongheng Zhang. (2014) Effect of High/Low Dose N-Acetylcysteine on Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis. COPD: Journal of Chronic Obstructive Pulmonary Disease 11:3, pages 351-358.
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Markus Bosmann & Peter A Ward. (2014) Protein-based therapies for acute lung injury: targeting neutrophil extracellular traps. Expert Opinion on Therapeutic Targets 18:6, pages 703-714.
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Articles from other publishers (8)

Kiran Dudhat & Harsha Patel. (2022) Preparation and evaluation of pirfenidone loaded chitosan nanoparticles pulmonary delivery for idiopathic pulmonary fibrosis. Future Journal of Pharmaceutical Sciences 8:1.
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Heshen Tian, Yumin Zhou, Longhui Tang, Fan Wu, Zhishan Deng, Bijia Lin, Peiyu Huang, Shaodan Wei, Dongxing Zhao, Jingping Zheng, Nanshan Zhong & Pixin Ran. (2020) High-dose N-acetylcysteine for long-term, regular treatment of early-stage chronic obstructive pulmonary disease (GOLD I–II): study protocol for a multicenter, double-blinded, parallel-group, randomized controlled trial in China. Trials 21:1.
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Evgenii Skurikhin, Vladimir Nebolsin, Darius Widera, Natalia Ermakova, Olga Pershina, Angelina Pakhomova, Vyacheslav Krupin, Edgar Pan, Mariia Zhukova, Fedor Novikov, Lubov Sandrikina, Sergey Morozov, Aslan Kubatiev & Alexander Dygai. (2020) Antifibrotic and Regenerative Effects of Treamid in Pulmonary Fibrosis. International Journal of Molecular Sciences 21:21, pages 8380.
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M. Molina-Molina, C. Machahua-Huamani, V. Vicens-Zygmunt, R. Llatjós, I. Escobar, E. Sala-Llinas, P. Luburich-Hernaiz, J. Dorca & A. Montes-Worboys. (2018) Anti-fibrotic effects of pirfenidone and rapamycin in primary IPF fibroblasts and human alveolar epithelial cells. BMC Pulmonary Medicine 18:1.
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Xingcai ZhangYuli CaiWei ZhangXianhai Chen. (2018) Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling. Biochemistry and Cell Biology 96:6, pages 742-751.
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Kohei Togami, Aki Miyao, Kei Miyakoshi, Yukimune Kanehira, Hitoshi Tada & Sumio Chono. (2015) Efficient Delivery to Human Lung Fibroblasts (WI-38) of Pirfenidone Incorporated into Liposomes Modified with Truncated Basic Fibroblast Growth Factor and Its Inhibitory Effect on Collagen Synthesis in Idiopathic Pulmonary Fibrosis. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 38:2, pages 270-276.
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Ping Zhao, Wen-Cheng Zhou, De-Lin Li, Xiao-Ting Mo, Liang Xu, Liu-Cheng Li, Wen-Hui Cui & Jian Gao. (2015) Total Glucosides of Danggui Buxue Tang Attenuate BLM-Induced Pulmonary Fibrosis via Regulating Oxidative Stress by Inhibiting NOX4. Oxidative Medicine and Cellular Longevity 2015, pages 1-10.
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Zheng Wang, Xiaoju Zhang, Yi Kang, Yanli Zeng, Hongmei Liu, Xiaoqian Chen & Lijun Ma. (2013) Stem cell therapy for idiopathic pulmonary fibrosis: How far are we from the bench to the bedside?. Journal of Biomedical Science and Engineering 06:08, pages 24-31.
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