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Drug Design, Development and Therapy Volume 10, 2016 - Issue
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Review

MEK inhibitors and their potential in the treatment of advanced melanoma: the advantages of combination therapy

Khiem A Tran1 Department of Dermatology, University of California, Davis, Sacramento, CA, USA
,
Michelle Y Cheng1 Department of Dermatology, University of California, Davis, Sacramento, CA, USA
,
Anupam Mitra1 Department of Dermatology, University of California, Davis, Sacramento, CA, USA
,
Hiromi Ogawa1 Department of Dermatology, University of California, Davis, Sacramento, CA, USA
,
Vivian Y Shi1 Department of Dermatology, University of California, Davis, Sacramento, CA, USA
,
Laura P Olney1 Department of Dermatology, University of California, Davis, Sacramento, CA, USA
,
April M Kloxin2 Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA
&
Emanual Maverakis1 Department of Dermatology, University of California, Davis, Sacramento, CA, USACorrespondence[email protected]
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Pages 43-52 | Published online: 21 Dec 2015

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Sheila López-Cobo, Natalia Pieper, Carmen Campos-Silva, Eva M. García-Cuesta, Hugh T. Reyburn, Annette Paschen & Mar Valés-Gómez. (2018) Impaired NK cell recognition of vemurafenib-treated melanoma cells is overcome by simultaneous application of histone deacetylase inhibitors. OncoImmunology 7:2.
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Peter Norman. (2016) Orphan drug approvals of 2015: Europe and the United States. Expert Opinion on Orphan Drugs 4:5, pages 491-500.
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Articles from other publishers (6)

Van Trung Hoang, Hoang Anh Thi Van, Cong Thao Trinh, Ngoc Trinh Thi Pham, Chinh Huynh, To Nguyen Ha, Phuong Hai Huynh, Hoang Quan Nguyen, Uyen Giao Vo & Thanh Thao Nguyen. (2021) Uterine Arteriovenous Malformation: A Pictorial Review of Diagnosis and Management. Journal of Endovascular Therapy 28:5, pages 659-675.
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Daniel-Clement Osei-Bordom, Sivesh Kamarajah & Niki Christou. (2021) Colorectal Cancer, Liver Metastases and Biotherapies. Biomedicines 9:8, pages 894.
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Diep Nguyen, Linda Yingqi Lin, Jeffrey O. Zhou, Emily Kibby, Twan W. Sia, Tiara D. Tillis, Narine Vapuryan, Ming-Ray Xu, Rajiv Potluri, YongJoon Shin, Elizabeth A. Erler, Naomi Bronkema, Daniel J. Boehlmer, Christopher D. Chung, Caroline Burkhard, Shirley H. Zeng, Michael Grasso, Lucila A. Acevedo, Ronen Marmorstein & Daniela Fera. (2020) Identification and Characterization of a B-Raf Kinase α-Helix Critical for the Activity of MEK Kinase in MAPK Signaling. Biochemistry 59:50, pages 4755-4765.
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João T. Barata & Mariana L. Oliveira. 2019. Molecular and Cell Biology of Cancer. Molecular and Cell Biology of Cancer 31 49 .
Carlos Alves, Inês Ribeiro, Ana Penedones, Diogo Mendes & Francisco Batel Marques. (2017) Risk of Ophthalmic Adverse Effects in Patients Treated with MEK Inhibitors: A Systematic Review and Meta-Analysis. Ophthalmic Research 57:1, pages 60-69.
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Viera Bajčiová. (2016) Malignant melanoma and new options of treatment. Onkologie 10:6, pages 256-262.
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