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Review

Uncovering undetected hypoglycemic events

Pages 57-74 | Published online: 08 Mar 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

P. Chevalier, T. Vandebrouck, D. De Keyzer, A. Mertens & M. Lamotte. (2016) Cost and co-morbidities associated with hypoglycemic inpatients in Belgium. Journal of Medical Economics 19:1, pages 44-52.
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Meryl Brod, Michael Wolden, Danielle Groleau & Donald M. Bushnell. (2014) Understanding the economic, daily functioning, and diabetes management burden of non-severe nocturnal hypoglycemic events in Canada: differences between type 1 and type 2. Journal of Medical Economics 17:1, pages 11-20.
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Stewart B Harris, Kamlesh Khunti, Mona Landin-Olsson, Claus B Galbo-Jørgensen, Mette Bøgelund, Barrie Chubb, Jens Gundgaard & Marc Evans. (2013) Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective. Patient Preference and Adherence 7, pages 925-936.
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A.H. Barnett, R. Brice, W. Hanif, J. James & H. Langerman. (2013) Increasing awareness of hypoglycaemia in patients with Type 2 diabetes treated with oral agents. Current Medical Research and Opinion 29:11, pages 1503-1513.
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Meryl Brod, Azhar Rana & Anthony H. Barnett. (2012) Adherence patterns in patients with type 2 diabetes on basal insulin analogues: missed, mistimed and reduced doses. Current Medical Research and Opinion 28:12, pages 1933-1946.
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Articles from other publishers (39)

Julie Maria Bøggild Brøsen, Rikke Mette Agesen, Amra Ciric AlibegovicHenrik Ullits AndersenHenning Beck-NielsenPeter GustenhoffTroels Krarup HansenChristoffer Georg Riber HedetoftTonny Joran JensenCharlotte Røn StolbergClaus Bogh JuhlSusanne Søgaard LercheKirsten NørgaardHans-Henrik ParvingLise TarnowBirger ThorsteinssonUlrik Pedersen-Bjergaard. (2022) Continuous Glucose Monitoring-Recorded Hypoglycemia with Insulin Degludec or Insulin Glargine U100 in People with Type 1 Diabetes Prone to Nocturnal Severe Hypoglycemia. Diabetes Technology & Therapeutics 24:9, pages 643-654.
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Yixiang Deng, Lu Lu, Laura Aponte, Angeliki M. Angelidi, Vera Novak, George Em Karniadakis & Christos S. Mantzoros. (2021) Deep transfer learning and data augmentation improve glucose levels prediction in type 2 diabetes patients. npj Digital Medicine 4:1.
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Alexander Turchin & Luisa F. Florez Builes. (2021) Using Natural Language Processing to Measure and Improve Quality of Diabetes Care: A Systematic Review. Journal of Diabetes Science and Technology 15:3, pages 553-560.
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Wael A. Alanazi. (2020) Role of Carnitine on Hematological Parameters and Attenuation of Cardiac (Pro)renin Receptor and Caspase-3 Expression in Hypoglycemia-induced Cardiac Hypertrophy. International Journal of Pharmacology 16:3, pages 191-200.
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Jeremy H. Pettus, Fang Liz Zhou, Leah Shepherd, Katie Mercaldi, Ronald Preblick, Phillip R. Hunt, Sachin Paranjape, Kellee M. Miller & Steven V. Edelman. (2019) Differences between patients with type 1 diabetes with optimal and suboptimal glycaemic control: A real‐world study of more than 30 000 patients in a US electronic health record database. Diabetes, Obesity and Metabolism 22:4, pages 622-630.
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Ulrik Pedersen‐Bjergaard, Saud Alsifri, Ronnie Aronson, Maja Cigrovski Berković, Gagik Galstyan, Helge Gydesen, Jesper Barner Lekdorf, Bernhard Ludvik, Erik Moberg, Ambady Ramachandran & Kamlesh Khunti. (2019) Comparison of the HAT study, the largest global hypoglycaemia study to date, with similar large real‐world studies. Diabetes, Obesity and Metabolism 21:4, pages 844-853.
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Tanja Pate, Simona Klemenčič, Tadej Battelino & Nataša Bratina. (2016) Fear of hypoglycemia, anxiety, and subjective well-being in parents of children and adolescents with type 1 diabetes. Journal of Health Psychology 24:2, pages 209-218.
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Rodrigo Nunes Lamounier, Bruno Geloneze, Silmara Oliveira Leite, Renan MontenegroJr.Jr., Lenita Zajdenverg, Milene Fernandes, Fabiano de Oliveira Griciunas, Mariana Narbot Ermetice & António Roberto Chacra. (2018) Hypoglycemia incidence and awareness among insulin-treated patients with diabetes: the HAT study in Brazil. Diabetology & Metabolic Syndrome 10:1.
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Pranay Goel, Durga Parkhi, Amlan Barua, Mita Shah & Saroj Ghaskadbi. (2018) A Minimal Model Approach for Analyzing Continuous Glucose Monitoring in Type 2 Diabetes. Frontiers in Physiology 9.
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Marjorie R. Ortiz. (2017) Hypoglycemia in Diabetes. Nursing Clinics of North America 52:4, pages 565-574.
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Freddy Goldberg Eliaschewitz & Tânia Barreto. (2016) Concepts and clinical use of ultra-long basal insulin. Diabetology & Metabolic Syndrome 8:1.
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Anthony P. Nunes, Jing Yang, Larry Radican, Samuel S. Engel, Karen Kurtyka, Kaan Tunceli, Shengsheng Yu, Kristy Iglay, Michael C. Doherty & David D. Dore. (2016) Assessing occurrence of hypoglycemia and its severity from electronic health records of patients with type 2 diabetes mellitus. Diabetes Research and Clinical Practice 121, pages 192-203.
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Shi-Wei Yang, Kyoung-Ha Park & Yu-Jie Zhou. (2016) The Impact of Hypoglycemia on the Cardiovascular System. Angiology 67:9, pages 802-809.
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Pavika J Lyngsie, Sandra Lopes & Jens Olsen. (2016) Incidence and cost of hypoglycemic events requiring medical assistance in a hospital setting in Denmark. Journal of Comparative Effectiveness Research 5:3, pages 239-247.
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Gyuri Kim, Yong-ho Lee, Mi Hye Han, Eui-Kyung Lee, Chong Hwa Kim, Hyuk Sang Kwon, In Kyung Jeong, Eun Seok Kang & Dae Jung Kim. (2016) Economic Burden of Hypoglycemia in Patients with Type 2 Diabetes Mellitus from Korea. PLOS ONE 11:3, pages e0151282.
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Wendy Klein-Schwartz, Gina L. Stassinos & Geoffrey K. Isbister. (2016) Treatment of sulfonylurea and insulin overdose. British Journal of Clinical Pharmacology 81:3, pages 496-504.
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Lisa Elliott, Carrie Fidler, Andrea Ditchfield & Trine Stissing. (2016) Hypoglycemia Event Rates: A Comparison Between Real-World Data and Randomized Controlled Trial Populations in Insulin-Treated Diabetes. Diabetes Therapy 7:1, pages 45-60.
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Dimitrios Baltzis, Maria G. Grammatikopoulou, Nikolaos Papanas, Christina-Maria Trakatelli, Evangelia Kintiraki, Maria N. Hassapidou & Christos Manes. (2016) Obese Patients with Type 2 Diabetes on Conventional Versus Intensive Insulin Therapy: Efficacy of Low-Calorie Dietary Intervention. Advances in Therapy 33:3, pages 447-459.
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Nanette C. Schloot, Axel Haupt, Morten Schütt, Klaus Badenhoop, Markus Laimer, Claudia Nicolay, Matthew Reaney, Katharina Fink & Reinhard W. Holl. (2016) Risk of severe hypoglycemia in sulfonylurea-treated patients from diabetes centers in Germany/Austria: How big is the problem? Which patients are at risk?. Diabetes/Metabolism Research and Reviews 32:3, pages 316-324.
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Diethelm Tschöpe, Peter Bramlage, Steffen Schneider & Anselm K Gitt. (2015) Incidence, characteristics and impact of hypoglycaemia in patients receiving intensified treatment for inadequately controlled type 2 diabetes mellitus. Diabetes and Vascular Disease Research 13:1, pages 2-12.
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Katie Baker. (2016) Comparison of bioartificial and artificial pancreatic transplantation as promising therapies for Type I Diabetes Mellitus. Bioscience Horizons 9, pages hzw002.
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Meryl Brod, Lise Højbjerre, Donald M. Bushnell & Charlotte Thim Hansen. (2015) Assessing the impact of non-severe hypoglycemic events and treatment in adults: development of the Treatment-Related Impact Measure—Non-severe Hypoglycemic Events (TRIM-HYPO). Quality of Life Research 24:12, pages 2971-2984.
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Marina Vladimirovna Shestakova, Michail Vladimirovich Antciferov, Alexander Yur'evich Mayorov, Luydmila Alexandrovna Ruyatkina, Ludmila Alexandrovna Suplotova, Sergey Anatol'evich Dogadin, Nikolay Borisovich Lebedev & Yana Gennadievna Alekseeva. (2015) Insulin degludec: a new basal insulin analogue with an ultra-long duration of action. Safety and efficacy in Russian patients with diabetes. Diabetes mellitus 18:4, pages 130-141.
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Emmanuel D. Williams, Steven C. Rogers, Xiaomin Zhang, Gohar Azhar & Jeanne Y. Wei. (2015) Elevated oxygen consumption rate in response to acute low-glucose stress: Metformin restores rate to normal level. Experimental Gerontology 70, pages 157-162.
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Lukas SchauppKlaus DonsaKatharina M. NeubauerJulia K. MaderFelix AbererBernhard HöllStephan SpatThomas AugustinPeter BeckThomas R. PieberJohannes Plank. (2015) Taking a Closer Look—Continuous Glucose Monitoring in Non-Critically Ill Hospitalized Patients with Type 2 Diabetes Mellitus Under Basal-Bolus Insulin Therapy. Diabetes Technology & Therapeutics 17:9, pages 611-618.
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Julia A. Carlson, Kay Craven & Kathryn Kolasa. (2015) Feeding Insulin. Nutrition Today 50:3, pages 109-116.
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Martin M. Grajower. (2015) Adding Rapid-Acting Insulin or Glp-1 Receptor Agonist to Basal Insulin: Penny Wise and Pound Foolish?. Endocrine Practice 21:1, pages 88-90.
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C. S. Wendel, G. G. Fotieo, J. H. Shah, J. Felicetta, B. H. Curtis & G. H. Murata. (2014) Incidence of non-severe hypoglycaemia and intensity of treatment among veterans with Type 2 diabetes in the USA: a prospective observational study. Diabetic Medicine 31:12, pages 1524-1531.
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Peter N. Weissman, Molly C. Carr, June Ye, Deborah T. Cirkel, Murray Stewart, Caroline Perry & Richard Pratley. (2014) HARMONY 4: randomised clinical trial comparing once-weekly albiglutide and insulin glargine in patients with type 2 diabetes inadequately controlled with metformin with or without sulfonylurea. Diabetologia 57:12, pages 2475-2484.
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N. Munro & A. H. Barnett. (2014) Incidence, worry and discussion about dosing irregularities and self-treated hypoglycaemia amongst HCPs and patients with type 2 diabetes: results from the UK cohort of the Global Attitudes of Patient and Physicians (GAPP2) survey. International Journal of Clinical Practice 68:6, pages 692-699.
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Jerry D. MeeceTeresa L. PearsonLinda M. Siminerio. (2014) Complementary Approaches to Improving Glucose Control—Insulin and Incretins. The Diabetes Educator 40:1_suppl, pages 4S-26S.
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Meryl Brod, Michael Wolden, Torsten Christensen & Donald M. Bushnell. (2013) Understanding the Economic Burden of Nonsevere Nocturnal Hypoglycemic Events: Impact on Work Productivity, Disease Management, and Resource Utilization. Value in Health 16:8, pages 1140-1149.
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Jeff Unger. (2013) Educating Patients About Hypoglycemia Prevention and Self-Management. Clinical Diabetes 31:4, pages 179-188.
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Stephen C.L. GoughAnuj Bhargava, Rajeev Jain, Henriette Mersebach, Søren Rasmussen & Richard M. Bergenstal. (2013) Low-Volume Insulin Degludec 200 Units/mL Once Daily Improves Glycemic Control Similarly to Insulin Glargine With a Low Risk of Hypoglycemia in Insulin-Naïve Patients With Type 2 Diabetes. Diabetes Care 36:9, pages 2536-2542.
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M. Brod, M. Wolden, T. Christensen & D. M. Bushnell. (2013) A nine country study of the burden of non‐severe nocturnal hypoglycaemic events on diabetes management and daily function. Diabetes, Obesity and Metabolism 15:6, pages 546-557.
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R.-P. Radermecker, C. Fayolle, J.-F. Brun, J. Bringer & E. Renard. (2013) Accuracy assessment of online glucose monitoring by a subcutaneous enzymatic glucose sensor during exercise in patients with type 1 diabetes treated by continuous subcutaneous insulin infusion. Diabetes & Metabolism 39:3, pages 258-262.
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Sean Surman & Linda Fleeman. (2013) Continuous Glucose Monitoring in Small Animals. Veterinary Clinics of North America: Small Animal Practice 43:2, pages 381-406.
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Srikanth Bellary, Hillary Cameron, Kirsty Macleod, Michael Malecha, Krisna Koria, Praveen Raja, Jesús Diago Cabezudo & John Ellison. (2012) Clinical evaluation of a novel test strip technology for blood glucose monitoring: Accuracy at hypoglycaemic glucose levels. Diabetes Research and Clinical Practice 98:3, pages 430-435.
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Padhraig Ryan. (2012) Paying for Performance. International Journal of Public and Private Healthcare Management and Economics 2:2, pages 1-16.
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