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Original Research

Preparation and evaluation of quercetin-loaded lecithin-chitosan nanoparticles for topical delivery

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Pages 1621-1630 | Published online: 10 Aug 2011

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Amit K. Jain, Sakshi Jain, Mohammed A. S. Abourehab, Parul Mehta & Prashant Kesharwani. (2022) An insight on topically applied formulations for management of various skin disorders. Journal of Biomaterials Science, Polymer Edition 33:18, pages 2406-2432.
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Yanqi Zhang, Lingyan Kong & Libo Tan. (2022) Effectiveness of nanoscale delivery systems on improving the bioavailability of lutein in rodent models: a systematic review. Critical Reviews in Food Science and Nutrition 62:9, pages 2375-2390.
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Poonam Parashar, Ifrah Mazhar, Jovita Kanoujia, Abhishek Yadav, Pranesh Kumar, Shubhini A. Saraf & Sudipta Saha. (2022) Appraisal of anti-gout potential of colchicine-loaded chitosan nanoparticle gel in uric acid-induced gout animal model. Archives of Physiology and Biochemistry 128:2, pages 547-557.
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Soad A Mohamad, Eman Maher Zahran, Maha Raafat Abdel Fadeel, Amgad Albohy & Mohamed A Safwat. (2021) New Acaciin-Loaded Self-Assembled Nanofibers as MPro Inhibitors Against BCV as a Surrogate Model for SARS-CoV-2. International Journal of Nanomedicine 16, pages 1789-1804.
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Wujun Dong, Jun Ye, Weijue Wang, Yanfang Yang, Hongliang Wang, Tong Sun, Lili Gao & Yuling Liu. (2020) Self-Assembled Lecithin/Chitosan Nanoparticles Based on Phospholipid Complex: A Feasible Strategy to Improve Entrapment Efficiency and Transdermal Delivery of Poorly Lipophilic Drug. International Journal of Nanomedicine 15, pages 5629-5643.
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Qingming Ma, Yang Gao, Wentao Sun, Jie Cao, Yan Liang, Shangcong Han, Xinyu Wang & Yong Sun. (2020) Self-Assembled chitosan/phospholipid nanoparticles: from fundamentals to preparation for advanced drug delivery. Drug Delivery 27:1, pages 200-215.
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Xiao-Yang Chu, Wei Huang, Yu-Li Wang, Ling-Wei Meng, Li-Qing Chen, Ming-Ji Jin, Lu Chen, Chun-Hong Gao, Cheng Ge, Zhong-Gao Gao & Chun-Sheng Gao. (2019) Improving antitumor outcomes for palliative intratumoral injection therapy through lecithin– chitosan nanoparticles loading paclitaxel– cholesterol complex. International Journal of Nanomedicine 14, pages 689-705.
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Sara Salatin, Farzaneh Lotfipour & Mitra Jelvehgari. (2019) A brief overview on nano-sized materials used in the topical treatment of skin and soft tissue bacterial infections. Expert Opinion on Drug Delivery 16:12, pages 1313-1331.
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Lenin Das, Monika Kaurav & Ravi Shankar Pandey. (2019) Phospholipid–polymer hybrid nanoparticle-mediated transfollicular delivery of quercetin: prospective implement for the treatment of androgenic alopecia. Drug Development and Industrial Pharmacy 45:10, pages 1654-1663.
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Swati Chauhan, Neha Gulati & Upendra Nagaich. (2019) Fabrication and evaluation of ultra deformable vesicles for atopic dermatitis as topical delivery. International Journal of Polymeric Materials and Polymeric Biomaterials 68:5, pages 266-277.
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Shahira F El-Menshawe, Adel A Ali, Mohamed A Rabeh & Nermeen M Khalil. (2018) Nanosized soy phytosome-based thermogel as topical anti-obesity formulation: an approach for acceptable level of evidence of an effective novel herbal weight loss product. International Journal of Nanomedicine 13, pages 307-318.
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Miaomiao Wu, Chenhui Li, Wenwen Du, Xiaoyuan Yang & Zunying Liu. (2018) Preparation of Chitosan/Rosemary Extract Nanoparticles and their Application for Inhibiting Lipid Oxidation in Grass Carp (Ctenopharyngodon idellus) during Cold Storage. Journal of Aquatic Food Product Technology 27:6, pages 759-770.
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Sedef Ilk, Necdet Saglam & Mustafa Özgen. (2017) Kaempferol loaded lecithin/chitosan nanoparticles: preparation, characterization, and their potential applications as a sustainable antifungal agent. Artificial Cells, Nanomedicine, and Biotechnology 45:5, pages 907-916.
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Liyao Liu, Cuiping Zhou, Xuejun Xia & Yuling Liu. (2016) Self-assembled lecithin/chitosan nanoparticles for oral insulin delivery: preparation and functional evaluation. International Journal of Nanomedicine 11, pages 761-769.
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Yosra SR Elnaggar, Sara M Talaat, Mohammed Bahey-El-Din & Ossama Y Abdallah. (2016) Novel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies. International Journal of Nanomedicine 11, pages 5531-5547.
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Giada Maramaldi, Stefano Togni, Ivan Pagin, Luca Giacomelli, Roberta Cattaneo, Roberto Eggenhöffner & Samuele E Burastero. (2016) Soothing and anti-itch effect of quercetin phytosome in human subjects: a single-blind study. Clinical, Cosmetic and Investigational Dermatology 9, pages 55-62.
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İpek Eroğlu, Erkan Azizoğlu, Mine Özyazıcı, Merve Nenni, Hande Gürer Orhan, Seda Özbal, Işıl Tekmen, İlgen Ertam, İdil Ünal & Özgen Özer. (2016) Effective topical delivery systems for corticosteroids: dermatological and histological evaluations. Drug Delivery 23:5, pages 1502-1513.
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Afreen Qidwai, Saba Khan, Shadab Md, Mohammad Fazil, Sanjula Baboota, Jasjeet K. Narang & Javed Ali. (2016) Nanostructured lipid carrier in photodynamic therapy for the treatment of basal-cell carcinoma. Drug Delivery 23:4, pages 1476-1485.
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Yingjie Zhai, Lili Zhao, Zimin Wang & Guangxi Zhai. (2016) RETRACTED ARTICLE: Preparation and characterization of novel lipid nanocapsules of ropivacaine for transdermal delivery. Drug Delivery 23:2, pages (619)-(628).
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Ying-Chen Chen, Chia-Yu Su, Hua-Jun Jhan, Hsiu-O Ho & Ming-Thau Sheu. (2015) Physical characterization and in vivo pharmacokinetic study of self-assembling amphotericin B-loaded lecithin-based mixed polymeric micelles. International Journal of Nanomedicine 10, pages 7265-7274.
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Rebekah Watkins, Ling Wu, Chenming Zhang, Richey M Davis & Bin Xu. (2015) Natural product-based nanomedicine: recent advances and issues. International Journal of Nanomedicine 10, pages 6055-6074.
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Guo Dong Zhao, Rui Sun, Shi Lei Ni & Qiang Xia. (2015) Development and characterisation of a novel chitosan-coated antioxidant liposome containing both coenzyme Q10 and alpha-lipoic acid. Journal of Microencapsulation 32:2, pages 157-165.
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Sandra Elisa Haas, Cristiane de Andrade, Pedro Ernesto da Silva Sansone, Silvia Guterres & Teresa Dalla Costa. (2014) Development of innovative oil-core self-organized nanovesicles prepared with chitosan and lecithin using a 23 full-factorial design. Pharmaceutical Development and Technology 19:7, pages 769-778.
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B.V.NAGAVARMA NAMBURI, HEMANTK. S. YADAV, HEMANTH S.AYAZ AHMED, VASUDHA LAKSHMI SUREDDY & H.G. SHIVAKUMAR. (2014) Formulation and Evaluation of Polymeric Nanoparticulate Gel for Topical Delivery. International Journal of Polymeric Materials and Polymeric Biomaterials 63:9, pages 476-485.
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Chellampillai Bothiraja, Bhagwat D Yojana, Atmaram P Pawar, Karimunnisa S Shaikh & Uday H Thorat. (2014) Fisetin-loaded nanocochleates: formulation, characterisation, in vitro anticancer testing, bioavailability and biodistribution study. Expert Opinion on Drug Delivery 11:1, pages 17-29.
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İpek Özcan, Erkan Azizoğlu, Taner Şenyiğit, Mine Özyazıcı & Özgen Özer. (2013) Enhanced dermal delivery of diflucortolone valerate using lecithin/chitosan nanoparticles: in-vitro and in-vivo evaluations. International Journal of Nanomedicine 8, pages 461-475.
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İpek Özcan, Erkan Azizoğlu, Taner Şenyiğit, Mine Özyazıcı & Özgen Özer. (2013) Comparison of PLGA and lecithin/chitosan nanoparticles for dermal targeting of betamethasone valerate. Journal of Drug Targeting 21:6, pages 542-550.
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Devasier Bennet & Sanghyo Kim. (2013) A Transdermal Delivery System to Enhance Quercetin Nanoparticle Permeability. Journal of Biomaterials Science, Polymer Edition 24:2, pages 185-209.
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Devasier Bennet, Mohana Marimuthu, Sanghyo Kim & Jeongho An. (2012) Dual drug-loaded nanoparticles on self-integrated scaffold for controlled delivery. International Journal of Nanomedicine 7, pages 3399-3419.
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